bcl-xL is critical for dendritic cell survival in vivo

Journal of Immunology

Volumn 173, Issue 7, 2004, Pages 4425-4432

  Hon, Huiming ^a   Rucker III, Edmund B ^b   Hennighausen, Lothar ^c   Jacob, Joshy ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; DNA VACCINE; GREEN FLUORESCENT PROTEIN; PROTEIN BCL XL; SMALL INTERFERING RNA; BCL2L1 PROTEIN, MOUSE; GLYCOPROTEIN P 15095; INFLUENZA VIRUS HEMAGGLUTININ; ISOPROTEIN; PROTEIN BCL 2; PROTEIN BCL X; VIRUS ANTIBODY;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDERMIS CELL; FLOW CYTOMETRY; IMMUNE RESPONSE; IMMUNIZATION; INFLUENZA VIRUS A; KNOCKOUT GENE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; ANIMAL; APOPTOSIS; BIOLISTIC TRANSFORMATION; BIOSYNTHESIS; C57BL MOUSE; CELL MOTION; CYTOLOGY; GENE SILENCING; GENE TARGETING; GENETIC COMPLEMENTATION; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; METHODOLOGY; MOUSE MUTANT; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, CD11C; APOPTOSIS; BCL-X PROTEIN; BIOLISTICS; CELL MOVEMENT; CELL SURVIVAL; DENDRITIC CELLS; GENE SILENCING; GENE TARGETING; GENETIC COMPLEMENTATION TEST; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; ORTHOMYXOVIRIDAE INFECTIONS; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA INTERFERENCE; VACCINES, DNA;

EID: 4644350391     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.7.4425     Document Type: Article

References (40)

1. Banchereau, J., F. Briere, C. Caux, J. Davoust, S. Lebecque, Y. J. Liu, B. Pulendran, and K. Palucka. 2000. Immunobiology of dendritic cells. Annu. Rev. Immunol. 18:767.
2. Guermonprez, P., J. Valladeau, L. Zitvogel, C. Thery, and S. Amigorena. 2002. Antigen presentation and T cell stimulation by dendritic cells. Annu. Rev. Immunol. 20:621.
3. Garg, S., A. Oran, J. Wajchman, S. Sasaki, C. H. Maris, J. A. Kapp, and J. Jacob. 2003. Genetic tagging shows increased frequency and longevity of antigen-presenting, skin-derived dendritic cells in vivo. Nat. Immunol. 4:907.
4. Riedl, E., H. Strobl, O. Majdic, and W. Knapp. 1997. TGF-β1 promotes in vitro generation of dendritic cells by protecting progenitor cells from apoptosis. J. Immunol. 158:1591.
5. L potentially regulate the susceptibility of human peripheral blood monocyte-derived dendritic cells to cell death at different developmental stages. Biomed. Pharmacother. 56:144.
6. Koch, F., C. Heufler, E. Kampgen, D. Schneeweiss, G. Bock, and G. Schuler. 1990. Tumor necrosis factor a maintains the viability of murine epidermal Langerhans cells in culture, but in contrast to granulocyte/macrophage colony-stimulating factor, without inducing their functional maturation. J. Exp. Med. 171:159.
7. Witmer-Pack, M. D., W. Olivier, J. Valinsky, G. Schuler, and R. M. Steinman. 1987. Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells. J. Exp. Med. 166:1484.
8. Rabinovich, G. A., C. M. Riera, and P. Iribarren. 1999. Granulocyte-macrophage colony-stimulating factor protects dendritic cells from liposome-encapsulated dichloromethylene diphosphonate-induced apoptosis through a Bcl-2-mediated pathway. Eur. J. Immunol. 29:563.
9. + dendritic cell precursors from multipotent progenitors is regulated by a discrete fas-mediated apoptotic schedule. J. Leukocyte Biol. 62:493.
10. Wong, B. R., R. Josien, S. Y. Lee, B. Sauter, H. L. Li, R. M. Steinman, and Y. Choi. 1997. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J. Exp. Med. 186:2075.
11. Koppi, T. A., T. Tough-Bement, D. M. Lewinsohn, D. H. Lynch, and M. R. Alderson. 1997. CD40 ligand inhibits Fas/CD95-mediated apoptosis of human blood-derived dendritic cells. Eur. J. Immunol. 27:3161.
12. Miga, A. J., S. R. Masters, B. G. Durell, M. Gonzalez, M. K. Jenkins, C. Maliszewski, H. Kikutani, W. F. Wade, and R. J. Noelle. 2001. Dendritic cell longevity and T cell persistence is controlled by CD154-CD40 interactions. Eur. J. Immunol. 31:959.
13. Granucci, F., C. Vizzardelli, N. Pavelka, S. Feau, M. Persico, E. Virzi, M. Rescigno, G. Moro, and P. Ricciardi-Castagnoli. 2001. Inducible IL-2 production by dendritic cells revealed by global gene expression analysis. Nat. Immunol. 2:882.
14. Boise, L. H., M. Gonzalez-Garcia, C. E. Postema, L. Ding, T. Lindsten, L. A. Turka, X. Mao, G. Nunez, and C. B. Thompson. 1993. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74:597.
15. L. Nature 379:554.
16. Grillot, D. A., M. Gonzalez-Garcia, D. Ekhterae, L, Duan, N. Inohara, S. Ohta, M. F. Seidin, and G. Nunez. 1997. Genomic organization, promoter region analysis, and chromosome localization of the mouse bcl-x gene. J. Immunol. 158:4750.
17. Motoyama, N., F. Wang, K, A. Roth, H. Sawa, K. Nakayama, K. Nakayama, I. Negishi, S. Senju, Q. Zhang, S. Fujii, et al. 1995. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science 267:1506.
18. Rucker, E. B., III, P. Dierisseau, K. U. Wagner, L. Garrett, A. Wynshaw-Boris, J. A. Flaws, and L. Hennighausen. 2000. Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis. Mol. Endocrinol. 14:1038.
19. Wagner, K. U., E. Claudio, E. B. Rucker III, G. Riedlinger, C. Broussard, P. L. Schwartzberg, U. Siebenlist, and L. Hennighausen. 2000. Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly. Development 127:4949.
20. + T cells after gene gun immunization. J. Exp. Med. 188:1075.
21. Tuschl, T. 2001. RNA interference and small interfering RNAs. Chembiochem. 2:239.
22. Sui, G., C. Soohoo, E. B. Affar, F. Gay, Y. Shi, and W. C. Forrester. 2002. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA 99:5515.
23. Zambrowicz, B. P., A. Imamoto, S. Fiering, L. A. Herzenberg, W.G. Kerr, and P. Soriano. 1997. Disruption of overlapping transcripts in the ROSA β geo 26 gene trap strain leads to widespread expression of β-galactosidase in mouse embryos and hematopoietic cells. Proc. Natl. Acad. Sci. USA 94:3789.
24. Soriano, P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21:70.
25. Nolan, G. P., S. Fiering, J. F. Nicholas, and L. A. Herzenberg. 1988. Fluorescence-activated cell analysis and sorting of viable mammalian cells based on β-D-galactosidase activity after transduction of Escherichia colt lacZ. Proc. Natl. Acad. Sci. USA 85:2603.
26. Bender, B. S., and P. A. Small, Jr. 1992. Influenza: pathogenesis and host defense. Semin. Respir. Infect. 7:38.
27. Ulmer, J. B. 2002. Influenza DNA vaccines. Vaccine 20(Suppl. 2):S74.
28. Sledz, C. A., M. Holko, M. J. de Veer, R. H. Silverman, and B. R. Williams. 2003. Activation of the interferon system by short-interfering RNAs. Nat. Cell Biol. 5:834.
29. Kim, T. W., C. F. Hung, M. Ling, J. Juang, L. He, J. M. Hardwick, S. Kumar, and T. C. Wu. 2003. Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins. J. Clin. Invest. 112:109.
30. Lincreases their resistance to prostate cancer-induced apoptosis and antitumor effect in mice. J. Immunol. 165:1956.
31. Nopora, A., and T. Brocker. 2002. Bcl-2 controls dendritic cell longevity in vivo. J. Immunol. 169:3006.
32. Bjorck, P., J. Banchereau, and L. Flores-Romo. 1997. CD40 ligation counteracts Fas-induced apoptosis of human dendritic cells. Int. Immunol. 9:365.
33. Sparwasser, T., R. M. Vabulas, B. Villmow, G. B. Lipford, and H. Wagner. 2000. Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins. Eur. J. Immunol. 30:3591.
34. Josien, R., H. L. Li, E. Ingulli, S. Sarma, B. R. Wong, M. Vologodskaia, R. M. Steinman, and Y. Choi. 2000. TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo. J. Exp. Med. 191:495.
35. van Stipdonk, M. J., E. E. Lemmens, and S. P. Schoenberger. 2001. Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation. Nat. Immunol. 2:423.
36. Iezzi, G., K. Karjalainen, and A. Lanzavecchia. 1998. The duration of antigenic stimulation determines the fate of naive and effector T cells. Immunity 8:89.
37. Mempel, T. R., S. E. Henrickson, and U. H. Von Andrian. 2004. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427:154.
38. Chattergoon, M. A., J. J. Kim, J. S. Yang, T. M. Robinson, D. J. Lee, T. Dentchev, D. M. Wilson, V. Ayyavoo, and D. B. Weiner. 2000. Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered Fas-mediated apoptosis. Nat. Biotechnol. 18:974.
39. Sasaki, S., R. R. Amara, A. E. Oran, J. M. Smith, and H. L. Robinson. 2001. Apoptosis-mediated enhancement of DNA-raised immune responses by mutant caspases. Nat. Biotechnol. 19:543.
40. Sasaki, S., K. Q. Xin, K. Okudela, K. Okuda, and N. Ishii. 2002. Immunomodulation by apoptosis-inducing caspases for an influenza DNA vaccine delivered by gene gun. Gene Ther. 9:828.