p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation

Cell Death and Differentiation

Volumn 10, Issue 4, 2003, Pages 451-460

  Schuler, M ^a,b   Maurer, U ^a   Goldstein, J C ^a   Breitenbucher F ^b   Hoffarth, S ^b   Waterhouse, N J ^a   Green, D R ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Apoptosis; Bax; Cytochrome c; Noxa; p53

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CYTOCHROME C; ONCOPROTEIN; PROTEIN BAX; PROTEIN BCL XL; PROTEIN MDM2; PROTEIN NOXA; PROTEIN P53; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; CONTROLLED STUDY; DOWN REGULATION; EMBRYO CELL; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; FIBROBLAST; GENE EXPRESSION; GENE INDUCTION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; STRESS; WILD TYPE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARRIER PROTEINS; CASPASES; CELLS, CULTURED; CYTOCHROME C GROUP; DOWN-REGULATION; ENZYME INHIBITORS; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; FETUS; FIBROBLASTS; GENE EXPRESSION REGULATION; MICE; MICE, KNOCKOUT; MITOCHONDRIA; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0037513376     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401180     Document Type: Review

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