Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

Nature

Volumn 419, Issue 6907, 2002, Pages 634-637

  Marsden, Vanessa S ^a   O’Connor, Liam ^a,g   O’Reilly, Lorraine A ^a   Silke, John ^a   Metcalf, Donald ^a   Ekert, Paul G ^a,b   Huang, David C S ^a   Cecconi, Francesco ^c   Kuida, Keisuke ^d   Tomaselli, Kevin J ^e   Roy, Sophie ^f   Nicholson, Don W ^f   Vaux, David L ^a   Bouillet, Philippe ^a   Adams, Jerry M ^a   Strasser, Andreas ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d VERTEX PHARMACEUTICALS   (United States)

^e PFIZER INC   (United States)

^f MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^g Department of Life Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; NEUROLOGY;

APOPTOSIS;

ENZYMES;

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE; CASPASE 9; CYTOCHROME C; ENZYME INHIBITOR; PROTEIN BCL 2;

CYTOLOGY;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; LYMPHOCYTE COUNT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; B-LYMPHOCYTES; CASPASE 9; CASPASES; CELLS, CULTURED; CYTOCHROME C GROUP; ENZYME ACTIVATION; HEMATOPOIESIS; MICE; MICE, INBRED C57BL; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; T-LYMPHOCYTES;

ANIMALIA; MAMMALIA;

EID: 0037057629     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01101     Document Type: Article

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