Requirement for CD4 T cell help in generating functional CD8 T cell memory

Science

Volumn 300, Issue 5617, 2003, Pages 337-339

  Shedlock, Devon J ^a   Shen, Hao ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CYTOLOGY;

CELL MEMORY;

CELLS;

CD4 ANTIGEN; CD8 ANTIGEN;

BIOLOGY; INFECTIVITY; MEMORY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DEPLETION; IMMUNE RESPONSE; INFECTION; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REINFECTION; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; ARENAVIRIDAE INFECTIONS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; IMMUNIZATION; IMMUNIZATION, SECONDARY; IMMUNOLOGIC MEMORY; LISTERIA INFECTIONS; LISTERIA MONOCYTOGENES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; RECOMBINANT PROTEINS; SPLEEN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER;

ANIMALIA;

EID: 0037432787     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1082305     Document Type: Article

References (23)

1. S. M. Kaech, E. J. Wherry, R. Ahmed, Nature Rev. Immunol. 2, 251 (2002).
2. J. P. Ridge, F. Di Rosa, P. Matzinger, Nature 393, 474 (1998).
3. S. R. Bennett et al., Nature 393, 478 (1998).
4. S. P. Schoenberger, R. E. Toes, E. I. van der Voort, R. Offringa, C. J. Melief, Nature 393, 480 (1998).
5. J. M. den Haan, M. J. Bevan, Proc. Natl. Acad. Sci. U.S.A. 97, 12950 (2000).
6. C. Bourgeois, B. Rocha, C. Tanchot, Science 297, 2060 (2002).
7. D. J. Shedlock et al., J. Immunol. 170, 2053 (2003).
8. H. Matloubian, R. J. Concepcion, R. Ahmed, J. Virol. 68, 8056 (1994).
9. M. G. von Herrath, M. Yokoyama, J. Dockter, M. B. Oldstone, J. L. Whitton, J. Virol. 70, 1072 (1996).
10. A. Rahemtulla et al., Nature 353, 180 (1991).
11. C. A. Janeway Jr., R. Medzhitov, Annu. Rev. Immunol. 20, 197 (2002).
12. J. Schneider et al., Immunol. Rev. 170, 29 (1999).
13. J. L. Whitton, N. Sheng, M. B. Oldstone, T. A. McKee, J. Virol. 67, 348 (1993).
14. Material and methods are available as supporting material on Science Online.
15. b/GP34-41. Recombinant VV expressing the GP33-41 epitope (MG34) was provided by J. L. Whitton (Scripps, La Jolla, CA) and is referred to, for clarity, as "rVV33" in this report.
16. K. E. Foulds et al., J. Immunol. 168, 1528 (2002).
17. K. Murali-Krishna et al., Immunity 8, 177 (1998).
18. G. T. Belz, P. G. Stevenson, M. R. Castrucci, J. D. Altman, P. C. Doherty, Proc. Natl. Acad. Sci. U.S.A. 97, 2725 (2000).
19. H. Liu, S. Andreansky, G. Diaz, T. Hogg, P. C. Doherty, J. Immunol. 168, 3477 (2002).
20. A. J. Zajac et al., J. Exp. Med. 188, 2205 (1998).
21. J. M. Riberdy, J. P. Christensen, K. Branum, P. C. Doherty, J. Virol. 74, 9762 (2000).
22. E. M. Janssen et al., Nature 421, 852 (2003).
23. We thank C. A. Hunter, J. L. Whitton, and J. D. Altman for providing reagents, and E. J. Pearce, M. Yuk, P. Bates, and members of the Shen laboratory for discussion and critical reading of this manuscript. Supported by NIH grant AI45025 (H.S.) and NIH training grant AI07632 (D.J.5.).