Cutting edge: Requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells

Journal of Immunology

Volumn 168, Issue 10, 2002, Pages 4827-4831

  Schluns, Kimberly S ^a   Williams, Kristina ^a   Ma, Averil ^a   Zheng, Xin X ^a   Lefrançois, Leo ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; HERMES ANTIGEN; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR;

ANIMAL CELL; ANTIGEN SPECIFICITY; ANTIVIRAL ACTIVITY; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; EFFECTOR CELL; GENE EXPRESSION; LYMPHOCYTE PROLIFERATION; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; VESICULAR STOMATITIS VIRUS;

EID: 0037093844     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.10.4827     Document Type: Article

References (23)

1. Interleukin 15: Biology and relevance to human disease
2. Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for immunotherapy
3. Cloning of a T cell growth factor that interacts with the β chain of the interleukin-2, receptor
4. Utilization of the β and γ chains of the IL-2 receptor by the novel cytokine IL-15
5. Identification and cloning of a novel IL-15 binding protein that is structurally related to the α chain of the IL-2 receptor
6. Functional characterization of the human interleukin-15 receptor α chain and close linkage of IL15RA and IL2RA genes
7. + T cell in vivo by IL-15
8. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
9. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin-15-deficient mice
10. Turnover of naive- and memory-phenotype T cells
11. + memory T cells by opposing cytokines
12. The interaction of antibody with the major surface glycoprotein of vesicular stomatitis virus
13. Age-dependent intestinal lymphoproliferative disorder due to stem cell factor receptor deficiency: Parameters in small and large intestine
14. Preferential localization of effector memory cells in nonlymphoid tissue
15. Phenotypic analysis of antigen-specific T lymphocytes
16. Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection
17. Targeting the IL-15 receptor with an antagonist IL-15 mutant/Fcγ2a protein blocks delayed-type hypersensitivity
18. Determination of lymphocyte division by flow cytometry
19. Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: Effector function is linked to proliferative capacity
20. Viruses and T cell turnover: Evidence for bystander proliferation
21. + T-cell memory determined by clonal burst size
22. Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells
23. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo