CD27 is required for generation and long-term maintenance of T cell immunity

Nature Immunology

Volumn 1, Issue 5, 2000, Pages 433-440

  Hendriks, Jenny ^a   Gravestein, Loes A ^a   Tesselaar, Kiki ^b   Van Lier, René A W ^b   Schumacher, Ton N M ^a   Borst, Jannie ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b CENTRAL LABORATORY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL; ARTICLE; C57BL MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL DIVISION; CYTOLOGY; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; IN VITRO STUDY; INFLUENZA VIRUS A; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; MOUSE MUTANT; ORTHOMYXOVIRUS INFECTION; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD27; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL DIVISION; IMMUNOLOGIC MEMORY; INFLUENZA A VIRUS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORTHOMYXOVIRIDAE INFECTIONS; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 0034329745     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/80877     Document Type: Article

References (54)

1. Arch, R. H., Gedrich, R. W. & Thompson, C. B. Tumor necrosis factor receptor-associated factors (TRAFs)- a family of adapter proteins that regulates life and death. Genes Dev. 12, 2821-2830 (1998).
2. Gravestein, L. A. & Borst, J. Tumor necrosis factor receptor family members in the immune response. Sem. Immunol. 10, 423-434 (1998).
3. Anderson, D. M. et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 390, 175-179 (1997).
4. Koch, F. et al. High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-10. J. Exp. Med. 184, 741-746 (1996).
5. Grell, M. et al. Induction of cell death by tumor necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-RI activation by endogenous membrane-anchored TNF. EMBO J. 18, 3034-3043 (1999).
6. Xu, Y., Cheng, G. & Baltimore, D. Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. Immunity 5, 407-415 (1996).
7. Yeh, W.-C. et al. Early lethality, functional NF-κB activation & increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity 7, 715-725 (1997).
8. Lee, S. Y., Reichlin, A., Santana, A., Sokol, K. A. Nussenzweig, M. C. & Choi, Y. TRAF2 is essential for JNK but not NF-κB activation and regulates lymphocyte proliferation and survival. Immunity 7, 703-713 (1997).
9. Rothe, M., Pan, M., G., Henzel, W. J., Ayres, T. M. & Goeddel, D. V. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 83, 1243-1232 (1995).
10. Liu, Z. -G., Hsu, H., Goeddel, D. V. & Karin, M. Dissection of TNF receptor I effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 87, 565-576 (1996).
11. Camerini, D., Walz, G., Loenen, W. A. M., Borst, J. & Seed, B. The T cell activation antigen CD27 is a member of the NGF/TNF receptor gene family. J. Immunol. 147, 3165-3169 (1991).
12. Gravestein, L. A. et al. Cloning and expression of murine CD27: comparison with 4-1BB another lymphocyte-specific member of the nerve growth factor receptor family. Eur. J. Immunol. 23, 943-950 (1993).
13. Goodwin, R. G. et al. Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor. Cell 73, 447-456 (1993).
14. Bowman, M. R. et al. The cloning of CD70 and its identification as the ligand for CD27. J. Immunol. 152, 1756-1761 (1994).
15. Tesselaar, K., Gravestein, L. A., van Schijndel, G. M. W., Borst, J. & van Lier, R. A. W. Characterizaton of murine CD70, the ligand of the TNF receptor family member CD27. J. Immunol. 159, 4959-4965 (1997).
16. Oshima, H. et al. Characterization of murine CD70 by molecular cloning and mAb. Int. Immunol. 10, 517-526 (1998).
17. Lens, S. M., Tesselaar, K., van Oers, M. H. J. & van Lier, R. A. W. Control of lymphocyte function through CD27-CD70 interactions. Sem. Immunol. 10, 491-499 (1998).
18. Van Lier, R. A. W. et al. Tissue distribution and biochemical and functional properties of Tp55 (CD27), an novel T cell differentiation antigen. J. Immunol. 139, 1589-1596 (1987).
19. Hintzen, R. Q., de Jong, R., Lens, S. M. A. & van Lier, R. A. W. CD27: marker and mediator of T-cell activation. Immunol. Today 15, 307-311 (1994).
20. Gravestein, L. A., Nieland, J. D., Kruisbeek, A. M. & Borst, J. Novel mAbs reveal potent co-stimulatory activity of murine CD27. Int. Immunol. 7, 551-557 (1995).
21. + T cells. J. Exp. Med. 186, 1-12 (1997).
22. + B lymphocyte subset. J. Immunol. 148, 3700-3705 (1992).
23. + peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J. Exp. Med. 188, 1679-1689 (1998).
24. Vinay, D. S. & Kwon, B. S. Role of 4-1BB in immune responses. Sem. Immunol. 10, 481-489 (1998).
25. Weinberg, A. D., Vella, A. T. & Croft, M. OX-40: life beyond the effector T cell stage. Sem. Immunol. 10, 471-480 (1998).
26. Hintzen, R. Q. et al. CD70 represents the human ligand for CD27. Int. Immunol. 6, 477-480 (1994).
27. Akiba, H. et al. Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis. J. Exp. Med. 191, 375-380 (2000).
28. Kobata, T., Agematsu, K., Kameoka, J., Schlossman, S. F., Morimoto, C. CD27 is a signal-transducing molecule involved in CD45RA+ naïve T cell cistimulation. J. Immunol. 153, 5422-5432 (1994).
29. Hintzen, R. Q. et al. Engagement of CD27 with its ligand CD70 provides a second signal for T cell activation. J. Immunol. 154, 2612-2623 (1995).
30. + T lymphocytes. J. Immunol. 154, 3686-3695 (1995).
31. Agematsu, K. et al. Generation of plasma cells from peripheral blood memory B cells: Synergistic effect of interleukin-10 and CD27/CD70 interaction. Blood 91, 173-180 (1998).
32. Lenschow, D. J., Walunas, T. L. & Bluestone, J. A. CD28/B7 system of T cell co-stimulation. Annu. Rev. Immunol. 14: 233-258 (1996).
33. + T cells in primary and secondary influenza pneumonia. Immunity 8, 683-691 (1998).
34. + memory T cells by viral variants. J. Exp. Med. 190, 1319-1328 (1999).
35. Gravestein, L. A., van Ewijk, W., Ossendorp, F. & Borst, J. CD27 cooperates with the pre-T cell receptor in the regulation of murine T cell development. J. Exp. Med. 184, 675-685 (1996).
36. Gravestein, L. A. et al. The Tumor Necrosis Factor receptor family member CD27 signals to Jun N-terminal kinase via Traf-2. Eur. J. Immunol 28, 2208-2216 (1998).
37. Akiba, H. et al. CD27, a member of the Tumor Necrosis Factor receptor superfamily, activates NF-kappaB and Stress-activated protein kinase/c-Jun N-terminal kinase via TRAF-2, TRAF-5 and NF-kappaB-inducing kinase. J. Biol. Chem. 273, 13353-13358 (1998).
38. Nakano, H. et al. Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation. Proc. Natl. Acad. Sci. USA 96, 9803-9808 (1999).
39. Grewal, I. S, Xu, J. & Flavell, R. A. Impairment of antigen-specific T cell priming in mice lacking CD40 ligand. Nature 378, 617-620 (1995).
40. Schoenberger, S. P., Toes, R. E. M., van derVoort, E. I. H., Offringa, R. & Melief, C. J. M. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 393, 480-483 (1998).
41. Bennett, S. R. M. et al. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature 393, 478-480 (1998).
42. DeBenedette, M., Wen T., Bachmann, M., Ohashi, P. S., Barber, B. H., Stocking, K. L., Peschon, J. J. & Watts, T. Analysis of 4-1BB Ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus. J. Immunol. 163, 4833-4841 (1999).
43. Tan, J. T., Whitmire, J. K., Ahmed, R., Pearson, T. C. & Larsen, C. P. 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses. J. Immunol. 163, 4859-4868 (1999).
44. Kopf, M., Ruedl, C., Schmitz, N., Gallimore, A., Lefrang, K., Ecabert, B., Odermatt, B. & Bachmann, M. F. OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL responses after virus infection. Immunity 11, 699-708 (1999).
45. Murata, K., Ishii, N., Takano, H., Miura, S., Ndhlovu, L. C., Nose, M., Noda, T. & Sugamura, K. Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand. J. Exp. Med. 191, 365-374 (2000).
46. Shahinian, A. et al. Differential T cell costimulatory requirements in CD28-deficient mice. Science 261, 609-612 (1993).
47. Whitmire, J. K. et al. CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection. J. Virol. 70, 8375-8381 (1996).
48. + T cell functions. J. Exp. Med. 183, 2209-2218 (1996).
49. Liu, Y., Wenger, R. H., Zhao, M. & Nielsen, P. J. Distinct costimulatory molecules are required for the induction of effector and memory cytotoxic T cell responses. J. Exp. Med. 185, 251-262 (1997).
50. Lumsden, J. M., Roberts, J. M., Harris, N. L., Peach, R. J. & Ronchese, F. Differential requirement for CD80 and CD80/CD86-dependent costimulation in the lung immune response to influenza virus. J. Immunol. 164, 79-85 (2000).
51. Chen, A. I., McAdam, A. J., Buhlmann, J. E., Scott, S., Lupher, M. L., Greenfield, E. A., Baum, P. R., Fanslow, W. C., Calderhead, D. M., Freeman, G. J. & Sharpe, A. H. Ox40-ligand has a critical costimulatory role in dendritic cell:T cell interactions. Immunity 11, 689-698 (1999).
52. + CTL response. J. Exp. Med. 183, 2129-2142 (1996).
53. Maxwell, J. R., Weinberg, A., Prell, R. A. & Vella, A. T. Danger and OX40 receptor synergize to enhance memory T cell survival by inhibiting peripheral deletion. J. Immunol. 164, 107-112 (2000).
54. Walker, L. S. K. et al. Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers. J. Exp. Med. 190, 1115-1122 (1999).