Recruitment of TNF receptor 1 to lipid rafts is essential for TNFα-mediated NF-κB activation

Immunity

Volumn 18, Issue 5, 2003, Pages 655-664

  Legler, Daniel F ^a,b   Micheau, Olivier ^a   Doucey, Marie Agnès ^a   Tschopp, Jürg ^a   Bron, Claude ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CHOLESTEROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPID; PROTEASOME; PROTEIN RIP; PROTEIN SERINE THREONINE KINASE; SPHINGOLIPID; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 1 ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CHEMICAL PROCEDURES; DYNAMICS; HUMAN; HUMAN CELL; MEMBRANE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SENSITIZATION;

EID: 0038742813     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(03)00092-X     Document Type: Article

References (56)

1. Algeciras-Schimnich A., Shen L., Barnhart B.C., Murmann A.E., Burkhardt J.K., Peter M.E. Molecular ordering of the initial signaling events of CD95. Mol. Cell. Biol. 22:2002;207-220.
2. Aravind L., Dixit V.M., Koonin E.V. Apoptotic molecular machinery. vastly increased complexity in vertebrates revealed by genome comparisons Science. 291:2001;1279-1284.
3. Ashkenazi A., Dixit V.M. Death receptors. signaling and modulation Science. 281:1998;1305-1308.
4. Baker S.J., Reddy E.P. Modulation of life and death by the TNF receptor superfamily. Oncogene. 17:1998;3261-3270.
5. Baldwin A.S. Jr. The NF-κB and IκB proteins. new discoveries and insights Annu. Rev. Immunol. 14:1996;649-683.
6. Balkwill F., Foxwell B., Brennan F. TNF is here to stay! Immunol. Today. 21:2000;470-471.
7. Baud V., Karin M. Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol. 11:2001;372-377.
8. Boldin M.P., Mett I.L., Wallach D. A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain'. FEBS Lett. 367:1995;39-44.
9. Brown D.A., London E. Structure and origin of ordered lipid domains in biological membranes. J. Membr. Biol. 164:1998;103-114.
10. Brown D.A., London E. Structure and function of sphingolipid- and cholesterol-rich membrane rafts. J. Biol. Chem. 275:2000;17221-17224.
11. Brown K.D., Hostager B.S., Bishop G.A. Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1). J. Exp. Med. 193:2001;943-954.
12. Budd R.C. Activation-induced cell death. Curr. Opin. Immunol. 13:2001;356-362.
13. Chen G., Cao P., Goeddel D.V. TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90. Mol. Cell. 9:2002;401-410.
14. Cottin V., Doan J.E., Riches D.W. Restricted localization of the TNF receptor CD120a to lipid rafts. a novel role for the death domain J. Immunol. 168:2002;4095-4102.
15. Cremesti A., Paris F., Grassme H., Holler N., Tschopp J., Fuks Z., Gulbins E., Kolesnick R. Ceramide enables Fas to cap and kill. J. Biol. Chem. 276:2001;23954-23961.
16. Deng L., Wang C., Spencer E., Yang L., Braun A., You J., Slaughter C., Pickart C., Chen Z.J. Activation of the IκB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell. 103:2000;351-361.
17. Devin A., Cook A., Lin Y., Rodriguez Y., Kelliher M., Liu Z. The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1. TRAF2 recruits IKK to TNFR1 while RIP mediates IKK activation Immunity. 12:2000;419-429.
18. Dhein J., Daniel P.T., Trauth B.C., Oehm A., Moller P., Krammer P.H. Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens. J. Immunol. 149:1992;3166-3173.
19. Feng X., Gaeta M.L., Madge L.A., Yang J.H., Bradley J.R., Pober J.S. Caveolin-1 associates with TRAF2 to form a complex that is recruited to tumor necrosis factor receptors. J. Biol. Chem. 276:2001;8341-8349.
20. Gajate C., Mollinedo F. The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells. Blood. 98:2001;3860-3863.
21. Grassme H., Jekle A., Riehle A., Schwarz H., Berger J., Sandhoff K., Kolesnick R., Gulbins E. CD95 signaling via ceramide-rich membrane rafts. J. Biol. Chem. 276:2001;20589-20596. a.
22. Grassme H., Schwarz H., Gulbins E. Molecular mechanisms of ceramide-mediated CD95 clustering. Biochem. Biophys. Res. Commun. 284:2001;1016-1030. b.
23. Harder T., Scheiffele P., Verkade P., Simons K. Lipid domain structure of the plasma membrane revealed by patching of membrane components. J. Cell Biol. 141:1998;929-942.
24. Holler N., Zaru R., Micheau O., Thome M., Attinger A., Valitutti S., Bodmer J.L., Schneider P., Seed B., Tschopp J. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat. Immunol. 1:2000;489-495.
25. Hostager B.S., Catlett I.M., Bishop G.A. Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling. J. Biol. Chem. 275:2000;15392-15398.
26. Hsu H., Xiong J., Goeddel D.V. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell. 81:1995;495-504.
27. Hsu H., Shu H.B., Pan M.G., Goeddel D.V. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell. 84:1996;299-308.
28. Hueber A.O., Bernard A.M., Herincs Z., Couzinet A., He H.T. An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes. EMBO Rep. 3:2002;190-196.
29. Janes P.W., Ley S.C., Magee A.I. Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor. J. Cell Biol. 147:1999;447-461.
30. Karin M., Ben-Neriah Y. Phosphorylation meets ubiquitination. the control of NF-κB activity Annu. Rev. Immunol. 18:2000;621-663.
31. Kaykas A., Worringer K., Sugden B. CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex. EMBO J. 20:2001;2641-2654.
32. Kelliher M.A., Grimm S., Ishida Y., Kuo F., Stanger B.Z., Leder P. The death domain kinase RIP mediates the TNF-induced NF-κB signal. Immunity. 8:1998;297-303.
33. Ko Y.G., Lee J.S., Kang Y.S., Ahn J.H., Seo J.S. TNFα-mediated apoptosis is initiated in caveolae-like domains. J. Immunol. 162:1999;7217-7223.
34. Krammer P.H. CD95's deadly mission in the immune system. Nature. 407:2000;789-795.
35. Lafont F., Simons K. Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling. Proc. Natl. Acad. Sci. USA. 98:2001;3180-3184.
36. Legler D.F., Doucey M.A., Cerottini J.C., Bron C., Luescher I.F. Selective inhibition of CTL activation by a dipalmitoyl-phospholipid that prevents the recruitment of signaling molecules to lipid rafts. FASEB J. 15:2001;1601-1603.
37. Liu Z.G., Hsu H., Goeddel D.V., Karin M. Dissection of TNF receptor 1 effector functions. JNK activation is not linked to apoptosis while NF-κB activation prevents cell death Cell. 87:1996;565-576.
38. Locksley R.M., Killeen N., Lenardo M.J. The TNF and TNF receptor superfamilies. integrating mammalian biology Cell. 104:2001;487-501.
39. Micheau O., Lens S., Gaide O., Alevizopoulos K., Tschopp J. NF-κB signals induce the expression of c-FLIP. Mol. Cell. Biol. 21:2001;5299-5305.
40. Muller S., Hoege C., Pyrowolakis G., Jentsch S. SUMO, ubiquitin's mysterious cousin. Nat. Rev. Mol. Cell Biol. 2:2001;202-210.
41. Natoli G., Costanzo A., Guido F., Moretti F., Levrero M. Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signaling. Biochem. Pharmacol. 56:1998;915-920.
42. Pham L.V., Tamayo A.T., Yoshimura L.C., Lo P., Terry N., Reid P.S., Ford R.J. A CD40 signalosome anchored in lipid rafts leads to constitutive activation of NF-κB and autonomous cell growth in B cell lymphomas. Immunity. 16:2002;37-50.
43. Rietveld A., Simons K. The differential miscibility of lipids as the basis for the formation of functional membrane rafts. Biochim. Biophys. Acta. 1376:1998;467-479.
44. Rothe M., Sarma V., Dixit V.M., Goeddel D.V. TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40. Science. 269:1995;1424-1427.
45. Sedwick, C.E., and Altman, A. (2002). Ordered just so: lipid rafts and lymphocyte function. Science's STKE, http://stke.sciencemag.org/cgi/content/full/sigtrans ;2002/122/re2.
46. Shen Z., Reznikoff G., Dranoff G., Rock K.L. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J. Immunol. 158:1997;2723-2730.
47. Simons K., Toomre D. Lipid rafts and signal transduction. Nat. Rev. Mol. Cell Biol. 1:2000;31-39.
48. Ting A.T., Pimentel-Muinos F.X., Seed B. RIP mediates tumor necrosis factor receptor 1 activation of NF-κB but not Fas/APO-1-initiated apoptosis. EMBO J. 15:1996;6189-6196.
49. Treier M., Staszewski L.M., Bohmann D. Ubiquitin-dependent c-Jun degradation in vivo is mediated by the Δ domain. Cell. 78:1994;787-798.
50. Veldman R.J., Maestre N., Aduib O.M., Medin J.A., Salvayre R., Levade T. A neutral sphingomyelinase resides in sphingolipid-enriched microdomains and is inhibited by the caveolin-scaffolding domain. potential implications in tumour necrosis factor signalling Biochem. J. 355:2001;859-868.
51. Vidalain P.O., Azocar O., Servet-Delprat C., Rabourdin-Combe C., Gerlier D., Manie S. CD40 signaling in human dendritic cells is initiated within membrane rafts. EMBO J. 19:2000;3304-3313.
52. Wallach D., Varfolomeev E.E., Malinin N.L., Goltsev Y.V., Kovalenko A.V., Boldin M.P. Tumor necrosis factor receptor and Fas signaling mechanisms. Annu. Rev. Immunol. 17:1999;331-367.
53. Wang C.Y., Mayo M.W., Korneluk R.G., Goeddel D.V., Baldwin A.S. Jr. NF-κB antiapoptosis. induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation Science. 281:1998;1680-1683.
54. Wang C., Deng L., Hong M., Akkaraju G.R., Inoue J., Chen Z.J. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature. 412:2001;346-351.
55. Zhang W., Trible R.P., Samelson L.E. LAT palmitoylation. its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation Immunity. 9:1998;239-246.
56. Zhang S.Q., Kovalenko A., Cantarella G., Wallach D. Recruitment of the IKK signalosome to the p55 TNF receptor. RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation Immunity. 12:2000;301-311.