Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly

Development

Volumn 127, Issue 22, 2000, Pages 4949-4958

  Wagner, K U ^a   Claudio, E ^a   Rucker III, E B ^a   Riedlinger, G ^a   Broussard, C ^a   Schwartzberg, P L ^a   Siebenlist, U ^a   Hennighausen, L ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Bax; Bc12 family; Bel x; Cre recombinase; Erythropoiesis; Hyperplasia; MMTV LTR

Indexed keywords

CRE RECOMBINASE; PROTEIN BAX; PROTEIN BCL X;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL DEATH; CELL HYPERPLASIA; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROID CELL; ERYTHROPOIESIS; GENE DELETION; GENE EXPRESSION; GENE LOCUS; GENETIC RECOMBINATION; HEMOLYTIC ANEMIA; HYPOXEMIA; MEGAKARYOCYTE; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; MUTANT; NONHUMAN; PRIORITY JOURNAL; RETICULOCYTE; SPLEEN; SPLENOMEGALY; STEM CELL; THROMBOCYTOPENIA;

ANEMIA, HEMOLYTIC; ANIMALS; APOPTOSIS; BASE SEQUENCE; BCL-X PROTEIN; CELL DIFFERENTIATION; CELL SURVIVAL; DNA PRIMERS; ERYTHROBLASTS; ERYTHROCYTES; GENE DELETION; INTEGRASES; MAMMARY TUMOR VIRUS, MOUSE; MEGAKARYOCYTES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS C-BCL-2; RETICULOCYTES; SPLEEN; SPLENOMEGALY; THROMBOCYTOPENIA; VIRAL PROTEINS;

EID: 0033635616     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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