The CD40-inducible Bcl-2 family member A1 protects B cells from antigen receptor-mediated apoptosis

Cellular Immunology

Volumn 200, Issue 1, 2000, Pages 56-62

  Craxton, Andrew ^a   Chuang, Peter I ^a   Shu, Geraldine ^a   Harlan, John M ^a   Clark, Edward A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE ANTIGEN; CD40 ANTIGEN; IMMUNOGLOBULIN M ANTIBODY; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X;

ANIMAL CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL PROTECTION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0034712193     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1006/cimm.2000.1616     Document Type: Article

References (22)

1. Scott D. W., Tuttle J., Livnat D., Haynes W., Cogswell J. P., Keng P. Lymphoma models for B-cell activation and tolerance. II. Growth inhibition by anti-mu of WEHI-231 and the selection and properties of resistant mutants. Cell. Immunol. 93:1985;124-131.
2. Tsubata T., Wu J., Honjo T. B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40. Nature (London). 364:1993;645-648.
3. Choi M. S., Boise L. H., Gottschalk A. R., Quintans J., Thompson C. B., Klaus G. G. The role of bcl-XL in CD40-mediated rescue from anti-mu-induced apoptosis in WEHI-231 B lymphoma cells. Eur. J. Immunol. 25:1995;1352-1357.
4. Wang Z., Karras J. G., Howard R. G., Rothstein T. L. Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells. J. Immunol. 155:1995;3722-3725.
5. Lin E. Y., Orlofsky A., Berger M. S., Prystowsky M. B. Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2. J. Immunol. 151:1993;1979-1988.
6. Karsan A., Yee E., Kaushansky K., Harlan J. M. Cloning of a human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells. Blood. 87:1996;3089-3096.
7. Tomayko M. M., Cancro M. P. Long-lived B cells are distinguished by elevated expression of A1. J. Immunol. 160:1998;107-111.
8. Clark E. A., Ledbetter J. A. Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50. Proc. Natl. Acad. Sci. USA. 83:1986;4494-4498.
9. Craxton A., Shu G., Graves J. D., Saklatvala J., Krebs E. G., Clark E. A. p38 MAPK is required for CD40-induced gene expression and proliferation in B lymphocytes. J. Immunol. 161:1998;3225-3236.
10. Pascual V., Liu Y-J., Magalski A., de Bouteiller O., Banchereau J., Capra J. D. Analysis of somatic mutation in five B cell subsets of human tonsil. J. Exp. Med. 180:1994;329-339.
11. Jakway J. P., Usinger W. R., Gold M. R., Mishell R. I., DeFranco A. L. Growth regulation of the B lymphoma cell line WEHI-231 by anti-immunoglobulin, lipopolysaccharide, and other bacterial products. J. Immunol. 137:1986;2225-2231.
12. Hoyt D. G., Mannix R. J., Rusnak J. M., Pitt B. R., Lazo J. S. Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells. Am. J. Physiol. 269:1995;L171-L177.
13. Van Kooten C., Banchereau J. CD40-CD40 ligand: A multifunctional receptor ligand pair. Adv. Immunol. 61:1996;1-77.
14. Sater R. A., Sandel P. C., Monroe J. G. B cell receptor-induced apoptosis in primary transitional murine B cells: signaling requirements and modulation by T cell help. Int. Immunol. 10:1998;1673-1682.
15. Valentine M. A., Licciardi K. A. Rescue from anti-IgM-induced programmed cell death by the B cell surface proteins CD20 and CD40. Eur. J. Immunol. 22:1992;3141-3148.
16. Schauer S. L., Wang Z., Sonenshein G. E., Rothstein T. L. Maintenance of nuclear factor-κB/Rel and c-myc expression during CD40 ligand rescue of WEHI 231 early B cells from receptor-mediated apoptosis through modulation of IκB proteins. J. Immunol. 157:1996;81-86.
17. WAF1/CIP1 in receptor-mediated apoptosis of WEHI 231 B lymphoma cells. J. Exp. Med. 187:1998;1671-1679.
18. Lee H. H., Dadgostar H., Cheng Q., Shu J., Cheng G. NF-κB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes. Proc. Natl. Acad. Sci. USA. 96:1999;9136-9141.
19. Kuss A. W., Knödel M., Berberich-Siebelt F., Lindemann D., Schimpl A., Berberich I. A1 expression is stimulated by CD40 in B cells and rescues WEHI 231 cells from anti-IgM-induced cell death. Eur. J. Immunol. 29:1999;3077-3088.
20. Wang C. Y., Mayo M. W., Korneluk R. G., Goeddel D. V., Baldwin A. S. Jr. NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science. 281:1998;1680-1683.
21. Grumont R. J., Rourke I. J., Gerondakis S. Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. Genes Dev. 13:1999;400-411.
22. Adams J. M., Cory S. The Bcl-2 protein family: Arbiters of cell survival. Science. 281:1998;1322-1326.