Replication Catastrophe: When a Checkpoint Fails because of Exhaustion

Molecular Cell

Volumn 66, Issue 6, 2017, Pages 735-749

  Toledo, Luis ^a,b   Neelsen, Kai John ^a   Lukas, Jiri ^a  

^a University of Copenhagen   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

ATR; cancer therapy; catastrophe; checkpoint; CHK1; DNA damage; DNA replication; RPA; WEE1

Indexed keywords

CANCER THERAPY; CELL CYCLE CHECKPOINT; CELL DIVISION; CELL PROLIFERATION; DNA REPLICATION; DNA STRAND BREAKAGE; GENOME; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL DEATH; DNA DAMAGE; DNA REPAIR; GENETICS; GENOMIC INSTABILITY; HUMAN; METABOLISM; NEOPLASMS; PATHOLOGY;

DNA; REPLICATION FACTOR A;

ANIMALS; CELL DEATH; CELL PROLIFERATION; DNA; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; GENOMIC INSTABILITY; HUMANS; NEOPLASMS; REPLICATION PROTEIN A;

EID: 85020771576     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2017.05.001     Document Type: Review

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