메뉴 건너뛰기




Volumn 32, Issue 24, 2012, Pages 4986-4997

Continued DNA synthesis in replication checkpoint mutants leads to fork collapse

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CHECKPOINT KINASE 2; DNA; HELICASE; HISTONE H2A; HYDROXYUREA; MINICHROMOSOME MAINTENANCE PROTEIN; PROTEIN MRC1; RAD52 PROTEIN; REPLICATION FACTOR A; UNCLASSIFIED DRUG;

EID: 84871880035     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01060-12     Document Type: Article
Times cited : (48)

References (66)
  • 1
    • 67349097341 scopus 로고    scopus 로고
    • Differential regulation of homologous recombination at DNA breaks and replication forks by the Mrc1 branch of the S-phase checkpoint
    • Alabert C, Bianco JN, Pasero P. 2009. Differential regulation of homologous recombination at DNA breaks and replication forks by the Mrc1 branch of the S-phase checkpoint. EMBO J. 28:1131-1141.
    • (2009) EMBO J. , vol.28 , pp. 1131-1141
    • Alabert, C.1    Bianco, J.N.2    Pasero, P.3
  • 2
    • 0035735472 scopus 로고    scopus 로고
    • Mrc1 transduces signals of DNA replication stress to activate Rad53
    • Alcasabas AA, et al. 2001. Mrc1 transduces signals of DNA replication stress to activate Rad53. Nat. Cell Biol. 3:958 -965.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 958-965
    • Alcasabas, A.A.1
  • 3
    • 34548789595 scopus 로고    scopus 로고
    • Replication in hydroxyurea: it's a matter of time
    • Alvino GM, et al. 2007. Replication in hydroxyurea: it's a matter of time. Mol. Cell. Biol. 27:6396-6406.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 6396-6406
    • Alvino, G.M.1
  • 4
    • 0030886099 scopus 로고    scopus 로고
    • Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase
    • Aparicio OM, Weinstein DM, Bell SP. 1997. Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase. Cell 91:59-69.
    • (1997) Cell , vol.91 , pp. 59-69
    • Aparicio, O.M.1    Weinstein, D.M.2    Bell, S.P.3
  • 5
    • 40749107055 scopus 로고    scopus 로고
    • Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote S-phase genome stability
    • Bailis JM, Luche DD, Hunter T, Forsburg SL. 2008. Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote S-phase genome stability. Mol. Cell. Biol. 28:1724 -1738.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 1724-1738
    • Bailis, J.M.1    Luche, D.D.2    Hunter, T.3    Forsburg, S.L.4
  • 6
    • 0032496322 scopus 로고    scopus 로고
    • Replication checkpoint enforced by kinases Cds1 and Chk1
    • Boddy MN, Furnari B, Mondesert O, Russell P. 1998. Replication checkpoint enforced by kinases Cds1 and Chk1. Science 280:909 -912.
    • (1998) Science , vol.280 , pp. 909-912
    • Boddy, M.N.1    Furnari, B.2    Mondesert, O.3    Russell, P.4
  • 7
    • 0034462093 scopus 로고    scopus 로고
    • Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1
    • Boddy MN, et al. 2000. Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1. Mol. Cell. Biol. 20:8758-8766.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8758-8766
    • Boddy, M.N.1
  • 8
    • 0032973830 scopus 로고    scopus 로고
    • Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases
    • Brondello JM, Boddy MN, Furnari B, Russell P. 1999. Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases.Mol. Cell. Biol. 19:4262- 4269.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4262-4269
    • Brondello, J.M.1    Boddy, M.N.2    Furnari, B.3    Russell, P.4
  • 9
    • 18244371925 scopus 로고    scopus 로고
    • Functional uncoupling ofMCMhelicase and DNA polymerase activities activates the ATR-dependent checkpoint
    • Byun TS, Pacek M, Yee MC, Walter JC, Cimprich KA. 2005. Functional uncoupling ofMCMhelicase and DNA polymerase activities activates the ATR-dependent checkpoint. Genes Dev. 19:1040 -1052.
    • (2005) Genes Dev. , vol.19 , pp. 1040-1052
    • Byun, T.S.1    Pacek, M.2    Yee, M.C.3    Walter, J.C.4    Cimprich, K.A.5
  • 10
    • 29144486147 scopus 로고    scopus 로고
    • Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations
    • Cobb JA, et al. 2005. Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. Genes Dev. 19:3055-3069.
    • (2005) Genes Dev. , vol.19 , pp. 3055-3069
    • Cobb, J.A.1
  • 11
    • 84858053395 scopus 로고    scopus 로고
    • Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases
    • De Piccoli G, et al. 2012. Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases. Mol. Cell 45:696 -704.
    • (2012) Mol. Cell , vol.45 , pp. 696-704
    • Piccoli, D.G.1
  • 12
    • 33645152790 scopus 로고    scopus 로고
    • Genomic mapping of single-stranded DNA in hydroxyurea- challenged yeasts identifies origins of replication
    • Feng W, et al. 2006. Genomic mapping of single-stranded DNA in hydroxyurea- challenged yeasts identifies origins of replication. Nat. Cell Biol. 8:148 -155.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 148-155
    • Feng, W.1
  • 13
    • 84868130069 scopus 로고    scopus 로고
    • Replication stress-induced chromosome breakage is correlated with replication fork progression and is preceded by single-stranded DNA formation
    • Feng W, Di Rienzi SC, Raghuraman MK, Brewer BJ. 2011. Replication stress-induced chromosome breakage is correlated with replication fork progression and is preceded by single-stranded DNA formation. G3 (Bethesda)1:327-335.
    • (2011) G3 Bethesda , vol.1 , pp. 327-335
    • Feng, W.1    Rienzi, D.S.C.2    Raghuraman, M.K.3    Brewer, B.J.4
  • 14
    • 39449123590 scopus 로고    scopus 로고
    • Cleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpoint
    • Froget B, Blaisonneau J, Lambert S, Baldacci G. 2008. Cleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpoint. Mol. Biol. Cell 19:445- 456.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 445-456
    • Froget, B.1    Blaisonneau, J.2    Lambert, S.3    Baldacci, G.4
  • 15
    • 68349125909 scopus 로고    scopus 로고
    • Microscopy techniques to examine DNA replication in fission yeast
    • Green MD, Sabatinos SA, Forsburg SL. 2009. Microscopy techniques to examine DNA replication in fission yeast. Methods Mol. Biol. 521:463- 482.
    • (2009) Methods Mol. Biol. , vol.521 , pp. 463-482
    • Green, M.D.1    Sabatinos, S.A.2    Forsburg, S.L.3
  • 16
    • 0032934063 scopus 로고    scopus 로고
    • The S/M checkpoint at 37 degrees C and the recovery of viability of the mutant poldeltats3 require the crb2+/rhp9+ gene in fission yeast
    • Grenon M, Tillit J, Piard K, Baldacci G, Francesconi S. 1999. The S/M checkpoint at 37 degrees C and the recovery of viability of the mutant poldeltats3 require the crb2+/rhp9+ gene in fission yeast. Mol. Gen.Genet. 260:522-534.
    • (1999) Mol. Gen.Genet. , vol.260 , pp. 522-534
    • Grenon, M.1    Tillit, J.2    Piard, K.3    Baldacci, G.4    Francesconi, S.5
  • 17
    • 79958075422 scopus 로고    scopus 로고
    • Mrc1 marks earlyfiring origins and coordinates timing and efficiency of initiation in fission yeast
    • Hayano M, Kanoh Y, Matsumoto S, Masai H. 2011. Mrc1 marks earlyfiring origins and coordinates timing and efficiency of initiation in fission yeast. Mol. Cell. Biol. 31:2380 -2391.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 2380-2391
    • Hayano, M.1    Kanoh, Y.2    Matsumoto, S.3    Masai, H.4
  • 18
    • 33947110984 scopus 로고    scopus 로고
    • Genome-wide localization of pre-RC sites and identification of replication origins in fission yeast
    • Hayashi M, et al. 2007. Genome-wide localization of pre-RC sites and identification of replication origins in fission yeast. EMBO J. 26:1327-1339.
    • (2007) EMBO J. , vol.26 , pp. 1327-1339
    • Hayashi, M.1
  • 19
    • 33750438774 scopus 로고    scopus 로고
    • Genome-wide characterization of fission yeast DNA replication origins
    • Heichinger C, Penkett CJ, Bahler J, Nurse P. 2006. Genome-wide characterization of fission yeast DNA replication origins. EMBO J. 25: 5171-5179.
    • (2006) EMBO J. , vol.25 , pp. 5171-5179
    • Heichinger, C.1    Penkett, C.J.2    Bahler, J.3    Nurse, P.4
  • 20
    • 0032559794 scopus 로고    scopus 로고
    • Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells
    • Jackson DA, Pombo A. 1998. Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells. J. Cell Biol.140:1285-1295.
    • (1998) J. Cell Biol. , vol.140 , pp. 1285-1295
    • Jackson, D.A.1    Pombo, A.2
  • 21
    • 84871851637 scopus 로고    scopus 로고
    • Heat induction of a novel Rad9 variant from a cryptic translation initiation site reduces mitotic commitment
    • [Epub ahead of print.] doi:10.1242/jcs.104075.
    • Janes S, et al. 13 July 2012. Heat induction of a novel Rad9 variant from a cryptic translation initiation site reduces mitotic commitment. J. Cell Sci. [Epub ahead of print.] doi:10.1242/jcs.104075.
    • (2012) J. Cell Sci.
    • Janes, S.1
  • 22
    • 17444416489 scopus 로고    scopus 로고
    • Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress
    • Kai M, Boddy MN, Russell P, Wang TS. 2005. Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Genes Dev. 19:919 -932.
    • (2005) Genes Dev. , vol.19 , pp. 919-932
    • Kai, M.1    Boddy, M.N.2    Russell, P.3    Wang, T.S.4
  • 23
    • 0042865938 scopus 로고    scopus 로고
    • S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex
    • Katou Y, et al. 2003. S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex. Nature 424:1078 -1083.
    • (2003) Nature , vol.424 , pp. 1078-1083
    • Katou, Y.1
  • 24
    • 0035503004 scopus 로고    scopus 로고
    • Regulation of replication timing in fission yeast
    • Kim SM, Huberman JA. 2001. Regulation of replication timing in fission yeast. EMBO J. 20:6115- 6126.
    • (2001) EMBO J. , vol.20 , pp. 6115-6126
    • Kim, S.M.1    Huberman, J.A.2
  • 25
    • 0345791546 scopus 로고    scopus 로고
    • Hydroxyurea arrests DNA replication by a mechanism that preserves basal dNTP pools
    • Koc A, Wheeler LJ, Mathews CK, Merrill GF. 2004. Hydroxyurea arrests DNA replication by a mechanism that preserves basal dNTP pools. J. Biol. Chem. 279:223-230.
    • (2004) J. Biol. Chem. , vol.279 , pp. 223-230
    • Koc, A.1    Wheeler, L.J.2    Mathews, C.K.3    Merrill, G.F.4
  • 26
    • 0032004942 scopus 로고    scopus 로고
    • S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe
    • Lindsay HD, et al. 1998. S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. Genes Dev. 12:382-395.
    • (1998) Genes Dev. , vol.12 , pp. 382-395
    • Lindsay, H.D.1
  • 27
    • 0035797383 scopus 로고    scopus 로고
    • The DNA replication checkpoint response stabilizes stalled replication forks
    • Lopes M, et al. 2001. The DNA replication checkpoint response stabilizes stalled replication forks. Nature 412:557-561.
    • (2001) Nature , vol.412 , pp. 557-561
    • Lopes, M.1
  • 28
    • 53149135030 scopus 로고    scopus 로고
    • Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint
    • Lou H, et al. 2008. Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint. Mol. Cell 32:106-117.
    • (2008) Mol. Cell , vol.32 , pp. 106-117
    • Lou, H.1
  • 29
    • 1442351990 scopus 로고    scopus 로고
    • Checkpoint-mediated control of replisome-forkassociation and signalling in response to replication pausing
    • Lucca C, et al. 2004. Checkpoint-mediated control of replisome-forkassociation and signalling in response to replication pausing. Oncogene 23:1206 -1213.
    • (2004) Oncogene , vol.23 , pp. 1206-1213
    • Lucca, C.1
  • 30
    • 13944261496 scopus 로고    scopus 로고
    • Temporal separation of replication and recombination requires the intra-S checkpoint
    • Meister P, et al. 2005. Temporal separation of replication and recombination requires the intra-S checkpoint. J. Cell Biol. 168:537-544.
    • (2005) J. Cell Biol. , vol.168 , pp. 537-544
    • Meister, P.1
  • 31
    • 33645210879 scopus 로고    scopus 로고
    • Rhp51- dependent recombination intermediates that do not generate checkpoint signal are accumulated in Schizosaccharomyces pombe rad60 and smc5/6 mutants after release from replication arrest
    • Miyabe I, Morishita T, Hishida T, Yonei S, Shinagawa H. 2006. Rhp51- dependent recombination intermediates that do not generate checkpoint signal are accumulated in Schizosaccharomyces pombe rad60 and smc5/6 mutants after release from replication arrest. Mol. Cell. Biol. 26:343-353.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 343-353
    • Miyabe, I.1    Morishita, T.2    Hishida, T.3    Yonei, S.4    Shinagawa, H.5
  • 32
    • 70350349896 scopus 로고    scopus 로고
    • Schizosaccharomyces pombe Cds1Chk2 regulates homologous recombination at stalled replication forks through the phosphorylation of recombination protein Rad60
    • Miyabe I, Morishita T, Shinagawa H, Carr AM. 2009. Schizosaccharomyces pombe Cds1Chk2 regulates homologous recombination at stalled replication forks through the phosphorylation of recombination protein Rad60. J. Cell Sci. 122:3638 -3643.
    • (2009) J. Cell Sci. , vol.122 , pp. 3638-3643
    • Miyabe, I.1    Morishita, T.2    Shinagawa, H.3    Carr, A.M.4
  • 33
    • 0028945424 scopus 로고
    • A kinase from fission yeast responsible for blocking mitosis in S phase
    • Murakami H, Okayama H. 1995. A kinase from fission yeast responsible for blocking mitosis in S phase. Nature 374:817- 819.
    • (1995) Nature , vol.374 , pp. 817-819
    • Murakami, H.1    Okayama, H.2
  • 34
    • 7644232348 scopus 로고    scopus 로고
    • Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway
    • Nakada D, Hirano Y, Sugimoto K. 2004. Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway. Mol. Cell. Biol. 24:10016 -10025.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 10016-10025
    • Nakada, D.1    Hirano, Y.2    Sugimoto, K.3
  • 35
    • 3042793923 scopus 로고    scopus 로고
    • Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast
    • Nakamura TM, Du LL, Redon C, Russell P. 2004. Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast. Mol. Cell. Biol. 24:6215- 6230.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 6215-6230
    • Nakamura, T.M.1    Du, L.L.2    Redon, C.3    Russell, P.4
  • 36
    • 31444452984 scopus 로고    scopus 로고
    • ATRIP associates with replication protein Acoated ssDNA through multiple interactions
    • Namiki Y, Zou L. 2006. ATRIP associates with replication protein Acoated ssDNA through multiple interactions. Proc. Natl. Acad. Sci. U. S. A. 103:580 -585.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 580-585
    • Namiki, Y.1    Zou, L.2
  • 37
    • 14744299899 scopus 로고    scopus 로고
    • Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex
    • Nedelcheva MN, et al. 2005. Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex. J. Mol. Biol. 347:509 -521.
    • (2005) J. Mol. Biol. , vol.347 , pp. 509-521
    • Nedelcheva, M.N.1
  • 38
    • 77953072305 scopus 로고    scopus 로고
    • Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms
    • Nestoras K, et al. 2010. Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms. Genes Dev. 24:1145-1159.
    • (2010) Genes Dev. , vol.24 , pp. 1145-1159
    • Nestoras, K.1
  • 39
    • 51349134176 scopus 로고    scopus 로고
    • Mcm4 C-terminal domain ofMCMhelicase prevents excessive formation of single-stranded DNA at stalled replication forks
    • Nitani N, Yadani C, Yabuuchi H, Masukata H, Nakagawa T. 2008. Mcm4 C-terminal domain ofMCMhelicase prevents excessive formation of single-stranded DNA at stalled replication forks. Proc. Natl. Acad. Sci.U. S. A. 105:12973-12978.
    • (2008) Proc. Natl. Acad. Sci.U. S. A. , vol.105 , pp. 12973-12978
    • Nitani, N.1    Yadani, C.2    Yabuuchi, H.3    Masukata, H.4    Nakagawa, T.5
  • 40
    • 0142027841 scopus 로고    scopus 로고
    • Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1
    • Noguchi E, Noguchi C, Du LL, Russell P. 2003. Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1. Mol. Cell. Biol. 23: 7861-7874.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 7861-7874
    • Noguchi, E.1    Noguchi, C.2    Du, L.L.3    Russell, P.4
  • 41
    • 0038506000 scopus 로고    scopus 로고
    • Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53
    • Osborn AJ, Elledge SJ. 2003. Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53. Genes Dev. 17:1755-1767.
    • (2003) Genes Dev. , vol.17 , pp. 1755-1767
    • Osborn, A.J.1    Elledge, S.J.2
  • 42
    • 32444450705 scopus 로고    scopus 로고
    • Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication
    • Pacek M, Tutter AV, Kubota Y, Takisawa H, Walter JC. 2006. Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. Mol. Cell 21:581-587.
    • (2006) Mol. Cell , vol.21 , pp. 581-587
    • Pacek, M.1    Tutter, A.V.2    Kubota, Y.3    Takisawa, H.4    Walter, J.C.5
  • 43
    • 5044236667 scopus 로고    scopus 로고
    • A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication
    • Pacek M, Walter JC. 2004. A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication. EMBO J. 23:3667-3676.
    • (2004) EMBO J. , vol.23 , pp. 3667-3676
    • Pacek, M.1    Walter, J.C.2
  • 45
    • 84857060479 scopus 로고    scopus 로고
    • dNTP pools determine fork progression and origin usage under replication stress
    • Poli J, et al. 2012. dNTP pools determine fork progression and origin usage under replication stress. EMBO J. 31:883- 894.
    • (2012) EMBO J. , vol.31 , pp. 883-894
    • Poli, J.1
  • 46
    • 84855271946 scopus 로고    scopus 로고
    • National Institutes of Health, Bethesda,MD.
    • Rasband, W. S. 2011. ImageJ. National Institutes of Health, Bethesda, MD. http://imagej.nih.gov/ij/.
    • (2011) ImageJ
    • Rasband, W.S.1
  • 47
    • 33745541640 scopus 로고    scopus 로고
    • Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover
    • Robert T, Dervins D, Fabre F, Gangloff S. 2006. Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover.EMBOJ. 25:2837-2846.
    • (2006) EMBOJ. , vol.25 , pp. 2837-2846
    • Robert, T.1    Dervins, D.2    Fabre, F.3    Gangloff, S.4
  • 48
    • 77956048941 scopus 로고    scopus 로고
    • Molecular genetics of Schizosaccharomyces pombe
    • Sabatinos SA, Forsburg SL. 2010. Molecular genetics of Schizosaccharomyces pombe. Methods Enzymol. 470:759 -795.
    • (2010) Methods Enzymol. , vol.470 , pp. 759-795
    • Sabatinos, S.A.1    Forsburg, S.L.2
  • 49
    • 0032497529 scopus 로고    scopus 로고
    • A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication
    • Santocanale C, Diffley JF. 1998. A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication. Nature 395:615-618.
    • (1998) Nature , vol.395 , pp. 615-618
    • Santocanale, C.1    Diffley, J.F.2
  • 50
    • 46249122812 scopus 로고    scopus 로고
    • Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks
    • Segurado M, Diffley JF. 2008. Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks. Genes Dev.22:1816 -1827.
    • (2008) Genes Dev. , vol.22 , pp. 1816-1827
    • Segurado, M.1    Diffley, J.F.2
  • 51
    • 0033781393 scopus 로고    scopus 로고
    • Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity
    • Snaith HA, Brown GW, Forsburg SL. 2000. Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity. Mol. Cell. Biol. 20:7922-7932.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7922-7932
    • Snaith, H.A.1    Brown, G.W.2    Forsburg, S.L.3
  • 52
    • 0037178740 scopus 로고    scopus 로고
    • Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
    • Sogo JM, Lopes M, Foiani M. 2002. Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 297:599-602.
    • (2002) Science , vol.297 , pp. 599-602
    • Sogo, J.M.1    Lopes, M.2    Foiani, M.3
  • 53
    • 24044463869 scopus 로고    scopus 로고
    • Mrc1 is required for normal progression of replication forks throughout chromatin in S. cerevisiae
    • Szyjka SJ, Viggiani CJ, Aparicio OM. 2005. Mrc1 is required for normal progression of replication forks throughout chromatin in S. cerevisiae. Mol. Cell 19:691- 697.
    • (2005) Mol. Cell , vol.19 , pp. 691-697
    • Szyjka, S.J.1    Viggiani, C.J.2    Aparicio, O.M.3
  • 54
    • 0034765174 scopus 로고    scopus 로고
    • Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast
    • Takeda T, et al. 2001. Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast. Mol. Biol. Cell 12:1257-1274.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1257-1274
    • Takeda, T.1
  • 55
    • 0035034925 scopus 로고    scopus 로고
    • Threonine-11, phosphorylated by Rad3 and atm in vitro, is required for activation of fission yeast checkpoint kinase Cds1
    • Tanaka K, Boddy MN, Chen XB, McGowan CH, Russell P. 2001. Threonine-11, phosphorylated by Rad3 and atm in vitro, is required for activation of fission yeast checkpoint kinase Cds1. Mol. Cell. Biol. 21: 3398-3404.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3398-3404
    • Tanaka, K.1    Boddy, M.N.2    Chen, X.B.3    Mcgowan, C.H.4    Russell, P.5
  • 56
    • 3542999251 scopus 로고    scopus 로고
    • Cds1 phosphorylation by Rad3-Rad26 kinase is mediated by forkhead-associated domain interaction with Mrc1
    • Tanaka K, Russell P. 2004. Cds1 phosphorylation by Rad3-Rad26 kinase is mediated by forkhead-associated domain interaction with Mrc1. J. Biol. Chem. 279:32079 -32086.
    • (2004) J. Biol. Chem. , vol.279 , pp. 32079-32086
    • Tanaka, K.1    Russell, P.2
  • 57
    • 0035736486 scopus 로고    scopus 로고
    • Mrc1 channels the DNA replication arrestsignal to checkpoint kinase Cds1
    • Tanaka K, Russell P. 2001. Mrc1 channels the DNA replication arrestsignal to checkpoint kinase Cds1. Nat. Cell Biol. 3:966 -972.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 966-972
    • Tanaka, K.1    Russell, P.2
  • 58
    • 78650054963 scopus 로고    scopus 로고
    • Fission yeast Swi1-Swi3 complex facilitates DNA binding of Mrc1
    • Tanaka T, et al. 2010. Fission yeast Swi1-Swi3 complex facilitates DNA binding of Mrc1. J. Biol. Chem. 285:39609 -39622.
    • (2010) J. Biol. Chem. , vol.285 , pp. 39609-39622
    • Tanaka, T.1
  • 59
    • 35349012676 scopus 로고    scopus 로고
    • Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1
    • Tsolou A, Lydall D. 2007. Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1. DNA Repair 6:1607-1617.
    • (2007) DNA Repair , vol.6 , pp. 1607-1617
    • Tsolou, A.1    Lydall, D.2
  • 60
    • 13744262292 scopus 로고    scopus 로고
    • Mcl1p is a polymerase alpha replication accessory factor important for S-phase DNA damage survival
    • Williams DR, McIntosh JR. 2005. Mcl1p is a polymerase alpha replication accessory factor important for S-phase DNA damage survival. Eukaryot. Cell 4:166 -177.
    • (2005) Eukaryot. Cell , vol.4 , pp. 166-177
    • Williams, D.R.1    Mcintosh, J.R.2
  • 61
    • 64049103676 scopus 로고    scopus 로고
    • Mus81, Rhp51(Rad51), and Rqh1 form an epistatic pathway required for the S-phase DNA damage checkpoint
    • Willis N, Rhind N. 2009. Mus81, Rhp51(Rad51), and Rqh1 form an epistatic pathway required for the S-phase DNA damage checkpoint. Mol.Biol. Cell 20:819-833.
    • (2009) Mol.Biol. Cell , vol.20 , pp. 819-833
    • Willis, N.1    Rhind, N.2
  • 62
    • 61349201535 scopus 로고    scopus 로고
    • Establishing the program of origin firing during S phase in fission yeast
    • Wu PY, Nurse P. 2009. Establishing the program of origin firing during S phase in fission yeast. Cell 136:852- 864.
    • (2009) Cell , vol.136 , pp. 852-864
    • Wu, P.Y.1    Nurse, P.2
  • 63
    • 33645846943 scopus 로고    scopus 로고
    • Two-stage mechanism for activation of theDNAreplication checkpoint kinase Cds1 in fission yeast
    • Xu YJ, Davenport M, Kelly TJ. 2006. Two-stage mechanism for activation of theDNAreplication checkpoint kinase Cds1 in fission yeast. Genes Dev. 20:990 -1003.
    • (2006) Genes Dev. , vol.20 , pp. 990-1003
    • Xu, Y.J.1    Davenport, M.2    Kelly, T.J.3
  • 64
    • 67650152234 scopus 로고    scopus 로고
    • Autoinhibition and autoactivation of the DNA replication checkpoint kinase Cds1
    • Xu YJ, Kelly TJ. 2009. Autoinhibition and autoactivation of the DNA replication checkpoint kinase Cds1. J. Biol. Chem. 284:16016 -16027.
    • (2009) J. Biol. Chem. , vol.284 , pp. 16016-16027
    • Xu, Y.J.1    Kelly, T.J.2
  • 65
    • 0032190082 scopus 로고    scopus 로고
    • Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1
    • Zeng Y, et al. 1998. Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1. Nature 395:507-510.
    • (1998) Nature , vol.395 , pp. 507-510
    • Zeng, Y.1
  • 66
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou L, Elledge SJ. 2003. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300:1542-1548.
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.