-
1
-
-
0032576768
-
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
-
Aladjem, M.I., B.T. Spike, L.W. Rodewald, T.J. Hope, M. Klemm, R. Jaenisch, and G.M. Wahl. 1998. ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Curr. Biol. 8: 145-155.
-
(1998)
Curr. Biol.
, vol.8
, pp. 145-155
-
-
Aladjem, M.I.1
Spike, B.T.2
Rodewald, L.W.3
Hope, T.J.4
Klemm, M.5
Jaenisch, R.6
Wahl, G.M.7
-
2
-
-
0028198383
-
Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast
-
Al-Khodairy, F., E. Fotou, K.S. Sheldrick, D.J. Griffiths, A.R. Lehmann, and A.M. Carr. 1994. Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast. Mol. Biol. Cell. 5: 147-160.
-
(1994)
Mol. Biol. Cell.
, vol.5
, pp. 147-160
-
-
Al-Khodairy, F.1
Fotou, E.2
Sheldrick, K.S.3
Griffiths, D.J.4
Lehmann, A.R.5
Carr, A.M.6
-
3
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
Banin, S., L. Moyal, S. Shieh, Y. Taya, C.W. Anderson, L. Chessa, N.I. Smorodinsky, C. Prives, Y. Reiss, Y. Shiloh et al. 1998. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281: 1674-1677.
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Shieh, S.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
Smorodinsky, N.I.7
Prives, C.8
Reiss, Y.9
Shiloh, Y.10
-
4
-
-
15844426692
-
Atm-deficient mice: A paradigm of ataxia telangiectasia
-
Barlow, C., S. Hirotsune, R. Paylor, M. Liyanage, M. Eckhaus, F. Collins, Y. Shiloh, J.N. Crawley, T. Ried, D. Tagle et al. 1996. Atm-deficient mice: A paradigm of ataxia telangiectasia. Cell 86: 159-171.
-
(1996)
Cell
, vol.86
, pp. 159-171
-
-
Barlow, C.1
Hirotsune, S.2
Paylor, R.3
Liyanage, M.4
Eckhaus, M.5
Collins, F.6
Shiloh, Y.7
Crawley, J.N.8
Ried, T.9
Tagle, D.10
-
5
-
-
0033552873
-
A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase
-
Blasina, A., D. Weyer IV, M.C. Laus, W.H. Luyten, A.E. Parker, and C.H. McGowan. 1999. A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase. Curr. Biol. 9: 1-10.
-
(1999)
Curr. Biol.
, vol.9
, pp. 1-10
-
-
Blasina, A.1
Weyer D. IV2
Laus, M.C.3
Luyten, W.H.4
Parker, A.E.5
McGowan, C.H.6
-
6
-
-
0032496322
-
Replication checkpoint enforced by kinases Cds1 and Chk1
-
Boddy, M.N., B. Furnari, O. Mondesert, and P. Russell. 1998. Replication checkpoint enforced by kinases Cds1 and Chk1. Science 280: 909-912.
-
(1998)
Science
, vol.280
, pp. 909-912
-
-
Boddy, M.N.1
Furnari, B.2
Mondesert, O.3
Russell, P.4
-
7
-
-
0033616828
-
A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage
-
Brown, A.L., C.H. Lee, J.K. Schwarz, N. Mitiku, H. Piwnica-Worms, and J.H. Chung. 1999. A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage. Proc. Natl. Acad. Sci. 96: 3745-3750.
-
(1999)
Proc. Natl. Acad. Sci.
, vol.96
, pp. 3745-3750
-
-
Brown, A.L.1
Lee, C.H.2
Schwarz, J.K.3
Mitiku, N.4
Piwnica-Worms, H.5
Chung, J.H.6
-
8
-
-
0034102337
-
ATR disruption leads to chromosomal fragmentation and early embryonic lethality
-
Brown, E.J. and D. Baltimore. 2000. ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes & Dev. 14: 397-402.
-
(2000)
Genes & Dev.
, vol.14
, pp. 397-402
-
-
Brown, E.J.1
Baltimore, D.2
-
9
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz, F., A. Dutriaux, C. Lengauer, T. Waldman, S. Zhou, J.P. Brown, J.M. Sedivy, K.W. Kinzler, and B. Vogelstein. 1998. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282: 1497-1501.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
10
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
Canman, C.E., D.S. Lim, K.A. Cimprich, Y. Taya, K. Tamai, K. Sakaguchi, E. Appella, M. B. Kastan, and J.D. Siliciano. 1998. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281: 1677-1679.
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Siliciano, J.D.9
-
11
-
-
0033533612
-
14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage
-
Chan, T.A., H. Hermeking, C. Lengauer, K.W. Kinzler, and B. Vogelstein. 1999. 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature 401: 616-620.
-
(1999)
Nature
, vol.401
, pp. 616-620
-
-
Chan, T.A.1
Hermeking, H.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
-
12
-
-
0033566082
-
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
-
Chaturvedi, P., W.K. Eng, Y. Zhu, M.R. Mattern, R. Mishra, M.R. Hurle, X. Zhang, R.S. Annan, Q. Lu, L.F. Faucette et al. 1999. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene 18: 4047-4054.
-
(1999)
Oncogene
, vol.18
, pp. 4047-4054
-
-
Chaturvedi, P.1
Eng, W.K.2
Zhu, Y.3
Mattern, M.R.4
Mishra, R.5
Hurle, M.R.6
Zhang, X.7
Annan, R.S.8
Lu, Q.9
Faucette, L.F.10
-
13
-
-
0034142325
-
Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53
-
Chehab, N.H., A. Malikzay, M. Appel, and T.D. Halazonetis. 2000. Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. Genes & Dev. 14: 278-288.
-
(2000)
Genes & Dev.
, vol.14
, pp. 278-288
-
-
Chehab, N.H.1
Malikzay, A.2
Appel, M.3
Halazonetis, T.D.4
-
14
-
-
0033558882
-
Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage
-
Chen, L., T.H. Liu, and N.C. Walworth. 1999. Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage. Genes & Dev. 13: 675-685.
-
(1999)
Genes & Dev.
, vol.13
, pp. 675-685
-
-
Chen, L.1
Liu, T.H.2
Walworth, N.C.3
-
15
-
-
9244229490
-
cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein
-
Cimprich, K.A., T.B. Shin, C.T. Keith, and S.L. Schreiber. 1996. cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein. Proc. Nad. Acad. Sci. 93: 2850-2855.
-
(1996)
Proc. Nad. Acad. Sci.
, vol.93
, pp. 2850-2855
-
-
Cimprich, K.A.1
Shin, T.B.2
Keith, C.T.3
Schreiber, S.L.4
-
16
-
-
0032472330
-
Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints
-
Cliby, W.A., C.J. Roberts, K.A. Cimprich, C.M. Stringer, J.R. Lamb, S.L. Schreiber, and S.H. Friend. 1998. Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints. EMBO J. 17: 159-169.
-
(1998)
EMBO J.
, vol.17
, pp. 159-169
-
-
Cliby, W.A.1
Roberts, C.J.2
Cimprich, K.A.3
Stringer, C.M.4
Lamb, J.R.5
Schreiber, S.L.6
Friend, S.H.7
-
17
-
-
0033527717
-
Requirement of ATM-dependent phosphorylation of Brca1 in the DNA damage response to double-strand breaks
-
Cortez, D., Y. Wang, J. Qin, and S.J. Elledge. 1999. Requirement of ATM-dependent phosphorylation of Brca1 in the DNA damage response to double-strand breaks. Science 286: 1162-1166.
-
(1999)
Science
, vol.286
, pp. 1162-1166
-
-
Cortez, D.1
Wang, Y.2
Qin, J.3
Elledge, S.J.4
-
18
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors
-
Donehower, L.A., M. Harvey, B.L. Slagle, M.J. McArthur, C.A. Montgonery Jr., J.S. Butel, and A. Bradley. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature 356: 215-221.
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgonery C.A., Jr.5
Butel, J.S.6
Bradley, A.7
-
19
-
-
0028951801
-
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability
-
Donehower, L.A., L.A. Godley, C.M. Aldaz, R. Pyle, Y.P. Shi, D. Pinkel, J. Gray, A. Bradley, D. Medina, and H.E. Varmus. 1995. Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability. Genes & Dev. 9: 882-895.
-
(1995)
Genes & Dev.
, vol.9
, pp. 882-895
-
-
Donehower, L.A.1
Godley, L.A.2
Aldaz, C.M.3
Pyle, R.4
Shi, Y.P.5
Pinkel, D.6
Gray, J.7
Bradley, A.8
Medina, D.9
Varmus, H.E.10
-
20
-
-
0029808466
-
Cell cycle checkpoints: Preventing an identity crisis
-
Elledge, S.J. 1996. Cell cycle checkpoints: Preventing an identity crisis. Science 274: 1664-1672.
-
(1996)
Science
, vol.274
, pp. 1664-1672
-
-
Elledge, S.J.1
-
21
-
-
0032511848
-
The murine gene p27Kip1 is haplo-insufficient for tumour suppression
-
Fero, M.L., E. Randel, K.E. Gurley, J.M. Roberts, and C.J. Kemp. 1998. The murine gene p27Kip1 is haplo-insufficient for tumour suppression. Nature 396: 177-180.
-
(1998)
Nature
, vol.396
, pp. 177-180
-
-
Fero, M.L.1
Randel, E.2
Gurley, K.E.3
Roberts, J.M.4
Kemp, C.J.5
-
22
-
-
0031172845
-
The Drosophila grapes gene is related to checkpoint gene chk1/ rad27 and is required for late syncytial division fidelity
-
Fogarty, P., S.D. Campbell, R. Abu-Shumays, B.S. Phalle, K.R. Yu, G.L. Uy, M.L. Goldberg, and W. Sullivan. 1997. The Drosophila grapes gene is related to checkpoint gene chk1/ rad27 and is required for late syncytial division fidelity. Curr. Biol. 7: 418-426.
-
(1997)
Curr. Biol.
, vol.7
, pp. 418-426
-
-
Fogarty, P.1
Campbell, S.D.2
Abu-Shumays, R.3
Phalle, B.S.4
Yu, K.R.5
Uy, G.L.6
Goldberg, M.L.7
Sullivan, W.8
-
23
-
-
0030768948
-
Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase
-
Furnari, B., N. Rhind, and P. Russell. 1997. Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase. Science 177: 1495-1497.
-
(1997)
Science
, vol.177
, pp. 1495-1497
-
-
Furnari, B.1
Rhind, N.2
Russell, P.3
-
24
-
-
15844371372
-
The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse
-
Hakem, R., J.L. de la Pompa, C. Sirard, R. Mo, M. Woo, A. Hakem, A. Wakeham, J. Potter, A. Reitmair, F. Billia et al. 1996. The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse. Cell 85: 1009-1023.
-
(1996)
Cell
, vol.85
, pp. 1009-1023
-
-
Hakem, R.1
De La Pompa, J.L.2
Sirard, C.3
Mo, R.4
Woo, M.5
Hakem, A.6
Wakeham, A.7
Potter, J.8
Reitmair, A.9
Billia, F.10
-
25
-
-
0034629072
-
DNA damage-induced activation of p53 by the checkpoint kinase Chk2
-
Hirao A., Y. Kong, S. Matsuoka, A. Wakeham, J. Ruland, H. Yoshida, D. Liu, S.J. Elledge, and T.W. Mak. 2000. DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science 287: 1824-1827.
-
(2000)
Science
, vol.287
, pp. 1824-1827
-
-
Hirao, A.1
Kong, Y.2
Matsuoka, S.3
Wakeham, A.4
Ruland, J.5
Yoshida, H.6
Liu, D.7
Elledge, S.J.8
Mak, T.W.9
-
26
-
-
0032587889
-
Heterozygosity of p21 WAF1/CIP1 enhances tumor cell proliferation and cyclin D1-associated kinase activity in a murine mammary cancer model
-
Jones, J.M., X.-S. Cui, D. Medina, and L.A. Donehower. 1999. Heterozygosity of p21 WAF1/CIP1 enhances tumor cell proliferation and cyclin D1-associated kinase activity in a murine mammary cancer model. Cell Growth Differ. 10: 213-222.
-
(1999)
Cell Growth Differ.
, vol.10
, pp. 213-222
-
-
Jones, J.M.1
Cui, X.-S.2
Medina, D.3
Donehower, L.A.4
-
27
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
Kastan, M.B., Q. Zhan, W.S. el-Deiry, F. Carrier, T. Jacks, W.V. Walsh, B.S. Plunkett, B. Vogelstein, and A.J. Fomace. 1992. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71: 587-597.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fomace, A.J.9
-
28
-
-
10244227923
-
The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes
-
Keegan, K.S., D.A. Holtzman, A.W. Plug, E.R. Christenson, E.E. Brainerd, G. Flaggs, N.J. Bentley, E.M. Taylor, M.S. Meyn, S.B. Moss et al. 1996. The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes. Genes & Dev. 10: 2423-2437.
-
(1996)
Genes & Dev.
, vol.10
, pp. 2423-2437
-
-
Keegan, K.S.1
Holtzman, D.A.2
Plug, A.W.3
Christenson, E.R.4
Brainerd, E.E.5
Flaggs, G.6
Bentley, N.J.7
Taylor, E.M.8
Meyn, M.S.9
Moss, S.B.10
-
29
-
-
0033621392
-
Substrate specificities and identification of putative substrates of ATM kinase family members
-
Kim, S.T., D.S. Lim, C.E. Canman, and M.B. Kastan. 1999. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274: 37538-37543.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37538-37543
-
-
Kim, S.T.1
Lim, D.S.2
Canman, C.E.3
Kastan, M.B.4
-
30
-
-
0033134794
-
Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25
-
Kumagai, A. and W.G. Dunphy. 1999. Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25. Genes & Dev. 13: 1067-1072.
-
(1999)
Genes & Dev.
, vol.13
, pp. 1067-1072
-
-
Kumagai, A.1
Dunphy, W.G.2
-
31
-
-
0032555924
-
The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts
-
Kumagai A., Z. Guo, K.H. Emami, S.X. Wang, and W.G. Dunphy. 1998. The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts. J. Cell. Biol. 142: 1559-1569.
-
(1998)
J. Cell. Biol.
, vol.142
, pp. 1559-1569
-
-
Kumagai, A.1
Guo, Z.2
Emami, K.H.3
Wang, S.X.4
Dunphy, W.G.5
-
32
-
-
0029909565
-
A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53
-
Lim, D.S. and P. Hasty. 1996. A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53. Mol. Cell. Biol. 16: 7133-7143.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 7133-7143
-
-
Lim, D.S.1
Hasty, P.2
-
33
-
-
0032004942
-
S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe
-
Lindsay, H.D., D.J. Griffiths, R.J. Edwards, P.U. Christensen, J.M. Murray, F. Osman, N. Walworth, and A.M. Carr. 1998. S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. Genes & Dev. 12: 382-395.
-
(1998)
Genes & Dev.
, vol.12
, pp. 382-395
-
-
Lindsay, H.D.1
Griffiths, D.J.2
Edwards, R.J.3
Christensen, P.U.4
Murray, J.M.5
Osman, F.6
Walworth, N.7
Carr, A.M.8
-
34
-
-
0033552943
-
Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein
-
Lopez-Girona, A., B. Furnari, O. Mondesert, and P. Russell. 1999. Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein. Nature 397: 172-175.
-
(1999)
Nature
, vol.397
, pp. 172-175
-
-
Lopez-Girona, A.1
Furnari, B.2
Mondesert, O.3
Russell, P.4
-
35
-
-
0027332996
-
Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosome instability syndromes?
-
Lu, X. and D.P. Lane. 1993. Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosome instability syndromes? Cell 75: 765-778.
-
(1993)
Cell
, vol.75
, pp. 765-778
-
-
Lu, X.1
Lane, D.P.2
-
36
-
-
0033594904
-
Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation
-
Luo, G., M.S. Yao, C.F. Bender, M. Mills, A.R. Bladl, A. Bradley, and J.H. Petrini. 1999. Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation. Proc. Natl. Acad. Sci. 96: 7376-7381.
-
(1999)
Proc. Natl. Acad. Sci.
, vol.96
, pp. 7376-7381
-
-
Luo, G.1
Yao, M.S.2
Bender, C.F.3
Mills, M.4
Bladl, A.R.5
Bradley, A.6
Petrini, J.H.7
-
37
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
-
Matsuoka, S., M. Huang, and S.J. Elledge. 1998. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 282: 1893-1897.
-
(1998)
Science
, vol.282
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
38
-
-
0033559207
-
Involvement of Chk1 kinase in prophase I arrest of Xenopus oocytes
-
Nakajo, N., T. Oe, K. Uto, and N. Sagata. 1999. Involvement of Chk1 kinase in prophase I arrest of Xenopus oocytes. Dev. Biol. 207: 432-444.
-
(1999)
Dev. Biol.
, vol.207
, pp. 432-444
-
-
Nakajo, N.1
Oe, T.2
Uto, K.3
Sagata, N.4
-
39
-
-
0031035528
-
Chk1 is a weel kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation
-
O'Connell, M.J., J.M. Raleigh, H.M. Verkade, and P. Nurse. 1997. Chk1 is a weel kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. EMBO J. 16: 545-554.
-
(1997)
EMBO J.
, vol.16
, pp. 545-554
-
-
O'Connell, M.J.1
Raleigh, J.M.2
Verkade, H.M.3
Nurse, P.4
-
40
-
-
0025747964
-
Programmed cell death (apoptosis) in murine blastocysts: Extracellular free-radicals, polyamines, and other cytotoxic agents
-
Parchment, R.E. 1991. Programmed cell death (apoptosis) in murine blastocysts: Extracellular free-radicals, polyamines, and other cytotoxic agents. In Vivo 5: 493-500.
-
(1991)
In Vivo
, vol.5
, pp. 493-500
-
-
Parchment, R.E.1
-
41
-
-
0030611095
-
Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
-
Peng, C-Y., P.R. Graves, R.S. Thoma, Z. Wu, A.S. Shaw, and H. Piwnica-Worms. 1997. Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277: 1501-1505.
-
(1997)
Science
, vol.277
, pp. 1501-1505
-
-
Peng, C.-Y.1
Graves, P.R.2
Thoma, R.S.3
Wu, Z.4
Shaw, A.S.5
Piwnica-Worms, H.6
-
42
-
-
0030593033
-
Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
-
Sanchez, Y., B.A. Desany, W.J. Jones, Q, Liu, B. Wang, and S.J. Elledge. 1996. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast Cell Cycle Checkpoint Pathways. Science 271: 357-360.
-
(1996)
Science
, vol.271
, pp. 357-360
-
-
Sanchez, Y.1
Desany, B.A.2
Jones, W.J.3
Liu, Q.4
Wang, B.5
Elledge, S.J.6
-
43
-
-
0030867582
-
Conservation of the Chk1 checkpoint pathway in mammals: Linkage DNA damage to Cdk regulation through Cdc25
-
Sanchez, Y., C. Wong, R.S. Thoma, R. Richman, Z. Wu, H. Piwnica-Worms, and S.J. Elledge. 1997. Conservation of the Chk1 checkpoint pathway in mammals: Linkage DNA damage to Cdk regulation through Cdc25. Science 277: 1497-1501.
-
(1997)
Science
, vol.277
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
Elledge, S.J.7
-
44
-
-
0033527787
-
Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms
-
Sanchez, Y., J. Bachant, H. Wang, F. Hu, D. Liu, M. Tetzlaff, and S.J. Elledge. 1999. Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms. Science 286: 1166-1171.
-
(1999)
Science
, vol.286
, pp. 1166-1171
-
-
Sanchez, Y.1
Bachant, J.2
Wang, H.3
Hu, F.4
Liu, D.5
Tetzlaff, M.6
Elledge, S.J.7
-
45
-
-
0029057336
-
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky, K., A. Bar-Shira, S. Gilad, G. Rotman, Y. Ziv, L. Vanagaite, D.A. Tagle, S. Smith, T. Uziel, S. Sfez et al. 1995. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268: 1749-1753.
-
(1995)
Science
, vol.268
, pp. 1749-1753
-
-
Savitsky, K.1
Bar-Shira, A.2
Gilad, S.3
Rotman, G.4
Ziv, Y.5
Vanagaite, L.6
Tagle, D.A.7
Smith, S.8
Uziel, T.9
Sfez, S.10
-
46
-
-
0030933762
-
Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
-
Sharan, S.K., M. Morimatsu, U. Albrecht, D.S. Lim, E. Regel, C. Dinh, A. Sands, G. Eichele, P. Hasty, and A. Bradley. 1997. Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2. Nature 386: 804-810.
-
(1997)
Nature
, vol.386
, pp. 804-810
-
-
Sharan, S.K.1
Morimatsu, M.2
Albrecht, U.3
Lim, D.S.4
Regel, E.5
Dinh, C.6
Sands, A.7
Eichele, G.8
Hasty, P.9
Bradley, A.10
-
47
-
-
0034142034
-
The human homologs of checkpoint kinases chk1 and cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
-
Shieh, S.Y., J. Ahn, K. Tamai, Y. Taya, and C. Prives. 2000. The human homologs of checkpoint kinases chk1 and cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes & Dev. 14: 289-300.
-
(2000)
Genes & Dev.
, vol.14
, pp. 289-300
-
-
Shieh, S.Y.1
Ahn, J.2
Tamai, K.3
Taya, Y.4
Prives, C.5
-
48
-
-
0030744385
-
DNA-replication checkpoint control at the Drosophila midblastula transition
-
Sibon, O.C., V.A. Stevenson, and W.E. Theurkauf. 1997. DNA-replication checkpoint control at the Drosophila midblastula transition. Nature 388: 93-97.
-
(1997)
Nature
, vol.388
, pp. 93-97
-
-
Sibon, O.C.1
Stevenson, V.A.2
Theurkauf, W.E.3
-
49
-
-
0033602478
-
The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition
-
Sibon, O.C., A. Laurencon, R. Hawley, and W.E. Theurkauf. 1999. The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition. Curr. Biol. 9: 302-312.
-
(1999)
Curr. Biol.
, vol.9
, pp. 302-312
-
-
Sibon, O.C.1
Laurencon, A.2
Hawley, R.3
Theurkauf, W.E.4
-
50
-
-
0033606968
-
Drosophila grapes/CHK1 mutants are defective in cyclin proteolysis and coordination of mitotic events
-
Su, T.T., S.D. Campbell, and P.H. O'Farrell. 1999. Drosophila grapes/CHK1 mutants are defective in cyclin proteolysis and coordination of mitotic events. Curr. Biol. 9: 919-922.
-
(1999)
Curr. Biol.
, vol.9
, pp. 919-922
-
-
Su, T.T.1
Campbell, S.D.2
O'Farrell, P.H.3
-
51
-
-
0029928222
-
Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways
-
Sun, Z., D.S. Fay, F. Marini, M. Foiani, and D.F. Stern. 1996. Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways. Genes & Dev. 10: 395-406.
-
(1996)
Genes & Dev.
, vol.10
, pp. 395-406
-
-
Sun, Z.1
Fay, D.S.2
Marini, F.3
Foiani, M.4
Stern, D.F.5
-
52
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
Tibbetts, R.S., K.M. Brumbaugh, J.M. Williams, J.N. Sarkaria, W.A. Cliby, S.Y. Shieh, Y. Taya, C. Prives, and R.T. Abraham. 1999. A role for ATR in the DNA damage-induced phosphorylation of p53. Genes & Dev. 13: 152-157.
-
(1999)
Genes & Dev.
, vol.13
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, J.M.3
Sarkaria, J.N.4
Cliby, W.A.5
Shieh, S.Y.6
Taya, Y.7
Prives, C.8
Abraham, R.T.9
-
53
-
-
0024162530
-
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
-
Tsukamoto, A.S., R. Grosschedl, R.C. Guman, T. Parslow, and H.E. Varmus. 1988. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell 55: 619-625.
-
(1988)
Cell
, vol.55
, pp. 619-625
-
-
Tsukamoto, A.S.1
Grosschedl, R.2
Guman, R.C.3
Parslow, T.4
Varmus, H.E.5
-
54
-
-
0032541321
-
Retention of wild-type p53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation
-
Venkatachalam, S., Y.P. Shi, S.N. Jones, H. Vogel, A. Bradley, D. Pinkel, and L.A. Donehower. 1998. Retention of wild-type p53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation. EMBO J. 17: 4657-4667.
-
(1998)
EMBO J.
, vol.17
, pp. 4657-4667
-
-
Venkatachalam, S.1
Shi, Y.P.2
Jones, S.N.3
Vogel, H.4
Bradley, A.5
Pinkel, D.6
Donehower, L.A.7
-
55
-
-
0029664616
-
Rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint
-
Walworth, N.C. and R. Bernards. 1996. Rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint. Science 271: 353-356.
-
(1996)
Science
, vol.271
, pp. 353-356
-
-
Walworth, N.C.1
Bernards, R.2
-
56
-
-
0027208148
-
Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2
-
Walworth, N., S. Davey, and D. Beach. 1993. Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2. Nature 363: 368-371.
-
(1993)
Nature
, vol.363
, pp. 368-371
-
-
Walworth, N.1
Davey, S.2
Beach, D.3
-
57
-
-
0032560556
-
Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control
-
Wright, J.A., K.S. Keegan, D.R. Herendeen, N.J. Bentley, A.M. Carr, M.F. Hoekstra, and P. Concannon. 1998. Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control. Proc. Natl Acad. Sci. 95: 7445-7450.
-
(1998)
Proc. Natl Acad. Sci.
, vol.95
, pp. 7445-7450
-
-
Wright, J.A.1
Keegan, K.S.2
Herendeen, D.R.3
Bentley, N.J.4
Carr, A.M.5
Hoekstra, M.F.6
Concannon, P.7
-
58
-
-
0029844048
-
Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma
-
Xu, Y., T. Ashley, E.E. Brainerd, R.T. Bronson, M.S. Meyn, and D. Baltimore. 1996. Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Genes & Dev. 10: 2411-2422.
-
(1996)
Genes & Dev.
, vol.10
, pp. 2411-2422
-
-
Xu, Y.1
Ashley, T.2
Brainerd, E.E.3
Bronson, R.T.4
Meyn, M.S.5
Baltimore, D.6
-
59
-
-
0033485758
-
Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells
-
Yamaguchi-Iwai, Y., E. Sonoda, M.S. Sasaki, C. Morrison, T. Haraguchi, Y. Hiraoka, Y.M. Yamashita, T. Yagi, M. Takata, C. Price et al. 1999. Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells. EMBO J. 18: 6619-6629.
-
(1999)
EMBO J.
, vol.18
, pp. 6619-6629
-
-
Yamaguchi-Iwai, Y.1
Sonoda, E.2
Sasaki, M.S.3
Morrison, C.4
Haraguchi, T.5
Hiraoka, Y.6
Yamashita, Y.M.7
Yagi, T.8
Takata, M.9
Price, C.10
-
60
-
-
0033561439
-
Maintenance of G2 arrest in the Xenopus oocyte: A role for 14-3-3-mediated inhibition of Cdc25 nuclear import
-
Yang, J., K. Winkler, M. Yoshida, and S. Kornbluth. 1999. Maintenance of G2 arrest in the Xenopus oocyte: A role for 14-3-3-mediated inhibition of Cdc25 nuclear import. EMBO J. 18: 2174-2183.
-
(1999)
EMBO J.
, vol.18
, pp. 2174-2183
-
-
Yang, J.1
Winkler, K.2
Yoshida, M.3
Kornbluth, S.4
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