HELB Is a Feedback Inhibitor of DNA End Resection

Molecular Cell

Volumn 61, Issue 3, 2016, Pages 405-418

  Tkáč, Ján ^a,b   Xu, Guotai ^c   Adhikary, Hemanta ^d,e   Young, Jordan T F ^a,b   Gallo, David ^b   Escribano Díaz, Cristina ^a   Krietsch, Jana ^d,e   Orthwein, Alexandre ^a   Munro, Meagan ^a   Sol, Wendy ^c   Al Hakim, Abdallah ^a   Lin, Zhen Yuan ^a   Jonkers, Jos ^c   Borst, Piet ^c   Brown, Grant W ^b   Gingras, Anne Claude ^a,b   Rottenberg, Sven ^c,f   Masson, Jean Yves ^d,e   Durocher, Daniel ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d Université Laval   (Canada)

^e UNIVERSITÉ LAVAL   (Canada)

^f UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA HELICASE; DNA HELICASE B; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; BLOOM SYNDROME HELICASE; BRCA1 PROTEIN; BRCA1 PROTEIN, HUMAN; BRCA1 PROTEIN, MOUSE; DNA LIGASE; DNA2 PROTEIN, HUMAN; EXO1 PROTEIN, HUMAN; EXO1 PROTEIN, MOUSE; EXODEOXYRIBONUCLEASE; HELB PROTEIN, HUMAN; HELB PROTEIN, MOUSE; OLAPARIB; PHTHALAZINE DERIVATIVE; PIPERAZINE DERIVATIVE; RECQ HELICASE; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CANCER CELL; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA DETERMINATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; 129 MOUSE; ANIMAL; C57BL MOUSE; DEFICIENCY; DNA END JOINING REPAIR; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; KNOCKOUT MOUSE; MAMMARY NEOPLASMS, EXPERIMENTAL; METABOLISM; MOUSE; PATHOLOGY; RNA INTERFERENCE; TIME FACTOR;

ANIMALS; BRCA1 PROTEIN; DNA END-JOINING REPAIR; DNA HELICASES; DNA REPAIR ENZYMES; EXODEOXYRIBONUCLEASES; FEEDBACK, PHYSIOLOGICAL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HELA CELLS; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; PHTHALAZINES; PIPERAZINES; POLY(ADP-RIBOSE) POLYMERASE INHIBITORS; RECQ HELICASES; RNA INTERFERENCE; S PHASE; TIME FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84957436995     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.12.013     Document Type: Article

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