The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage

Nature Communications

Volumn 6, Issue , 2015, Pages

  Fu, Haiqing ^a   Martin, Melvenia M ^a   Regairaz, Marie ^a   Huang, Liang ^a   You, Yang ^a   Lin, Chi Mei ^a   Ryan, Michael ^b   Kim, Ryangguk ^b   Shimura, Tsutomu ^c   Pommier, Yves ^a   Aladjem, Mirit I ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b In Silico Solutions   (United States)

^c NATIONAL INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; DOUBLE STRANDED DNA; ENDONUCLEASE; ENDONUCLEASE MUS81; OKAZAKI FRAGMENT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; MUS81 PROTEIN, HUMAN; XERODERMA PIGMENTOSUM GROUP F PROTEIN;

DNA; ENZYME ACTIVITY; GENE EXPRESSION; GROWTH;

ARTICLE; CANCER CELL; CELL CYCLE CHECKPOINT; CELL CYCLE PROGRESSION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA REPLICATION ORIGIN; DNA STRAND; DNA STRAND BREAKAGE; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME PHOSPHORYLATION; FLUORESCENCE IN SITU HYBRIDIZATION; HCT116 CELL LINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PHENOTYPE; SITE DIRECTED MUTAGENESIS; CELL CYCLE; COMET ASSAY; GENE INACTIVATION; GENE SILENCING; GENETICS; HCT 116 CELL LINE; METABOLISM;

CELL CYCLE; CELL SURVIVAL; COMET ASSAY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA-BINDING PROTEINS; ENDONUCLEASES; GENE KNOCKDOWN TECHNIQUES; GENE KNOCKOUT TECHNIQUES; HCT116 CELLS; HUMANS;

EID: 84928019072     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7746     Document Type: Article

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