메뉴 건너뛰기




Volumn 12, Issue 18, 1998, Pages 2956-2970

Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway

Author keywords

Checkpoint pathway; DNA replication; Nucleotide levels; Ribonucleotide reductase; S phase

Indexed keywords

DNA; RIBONUCLEOTIDE REDUCTASE; RNA;

EID: 0032530824     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.18.2956     Document Type: Article
Times cited : (391)

References (48)
  • 1
    • 0028198383 scopus 로고
    • Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast
    • Al-Khodairy, F., E. Fotou, K.S. Sheldrick, D.J.F. Griffiths, A.R. Lehmann, and A.M. Carr. 1994. Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast. Mol. Biol. Cell 5: 147-160.
    • (1994) Mol. Biol. Cell , vol.5 , pp. 147-160
    • Al-Khodairy, F.1    Fotou, E.2    Sheldrick, K.S.3    Griffiths, D.J.F.4    Lehmann, A.R.5    Carr, A.M.6
  • 2
    • 0027984387 scopus 로고
    • A family of vectors that facilitate transposon and insertional mutagenesis of cloned genes in yeast
    • Allen, J.B. and S.J. Elledge. 1994. A family of vectors that facilitate transposon and insertional mutagenesis of cloned genes in yeast. Yeast 10: 1267-1272.
    • (1994) Yeast , vol.10 , pp. 1267-1272
    • Allen, J.B.1    Elledge, S.J.2
  • 3
    • 0027968012 scopus 로고
    • The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast
    • Allen, J.B., Z. Zhou, W. Siede, E.C. Friedberg, and S.J. Elledge. 1994. The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast. Genes & Dev. 8: 2416-2428.
    • (1994) Genes & Dev. , vol.8 , pp. 2416-2428
    • Allen, J.B.1    Zhou, Z.2    Siede, W.3    Friedberg, E.C.4    Elledge, S.J.5
  • 5
    • 0029379619 scopus 로고
    • The chk1 pathway is required to prevent mitosis following cell-cycle arrest at 'start'
    • Carr, A.M., M. Moudjou, N.J. Bentley, and I.M. Hagan. 1995. The chk1 pathway is required to prevent mitosis following cell-cycle arrest at 'start'. Curr. Biol. 5: 1179-1190.
    • (1995) Curr. Biol. , vol.5 , pp. 1179-1190
    • Carr, A.M.1    Moudjou, M.2    Bentley, N.J.3    Hagan, I.M.4
  • 6
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: Preventing an identity crisis
    • Elledge, S.J. 1996. Cell cycle checkpoints: preventing an identity crisis. Science 274: 1664-1672.
    • (1996) Science , vol.274 , pp. 1664-1672
    • Elledge, S.J.1
  • 7
    • 0025350420 scopus 로고
    • Two genes differentially regulated in the cell cycle and by DNA-damaging agents encode alternative regulatory subunits of ribonucleotide reductase
    • Elledge, S.J. and R.W. Davis. 1990. Two genes differentially regulated in the cell cycle and by DNA-damaging agents encode alternative regulatory subunits of ribonucleotide reductase. Genes & Dev. 4: 740-751.
    • (1990) Genes & Dev. , vol.4 , pp. 740-751
    • Elledge, S.J.1    Davis, R.W.2
  • 8
    • 0026022605 scopus 로고
    • Lambda YES: A multifunctional cDNA expression vector for the isolation of genes by complementation of yeast and E. coli mutations
    • Elledge, S.J., J. Mulligan, S. Ramer, M. Spottswood, and R.W. Davis 1991. Lambda YES: A multifunctional cDNA expression vector for the isolation of genes by complementation of yeast and E. coli mutations. Proc. Natl. Acad. Sci. 88: 1731-1734.
    • (1991) Proc. Natl. Acad. Sci. , vol.88 , pp. 1731-1734
    • Elledge, S.J.1    Mulligan, J.2    Ramer, S.3    Spottswood, M.4    Davis, R.W.5
  • 9
    • 0026582672 scopus 로고
    • Ribonucleotide reductase: Regulation, regulation, regulation
    • Elledge, S.J., Z. Zhou, and J.B. Allen. 1992. Ribonucleotide reductase: Regulation, regulation, regulation. Trends Bioehem. Sci. 17: 119-123.
    • (1992) Trends Bioehem. Sci. , vol.17 , pp. 119-123
    • Elledge, S.J.1    Zhou, Z.2    Allen, J.B.3
  • 11
    • 0026482601 scopus 로고
    • Fission yeast genes involved in coupling mitosis to completion of DNA replication
    • Enoch, T., A. Carr, and P. Nurse. 1992. Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes & Dev. 6: 2035-2046.
    • (1992) Genes & Dev. , vol.6 , pp. 2035-2046
    • Enoch, T.1    Carr, A.2    Nurse, P.3
  • 12
    • 0018712697 scopus 로고
    • Fidelity of replication of phage phi X174 DNA by DNA polymerase III holoenzyme: Spontaneous mutation by misincorporation
    • Fersht, A.R. 1979. Fidelity of replication of phage phi X174 DNA by DNA polymerase III holoenzyme: Spontaneous mutation by misincorporation. Proc. Natl. Acad Sci. 76: 4946-4950.
    • (1979) Proc. Natl. Acad Sci. , vol.76 , pp. 4946-4950
    • Fersht, A.R.1
  • 17
    • 0030768948 scopus 로고    scopus 로고
    • Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase
    • Furnari, B., N. Rhind, and P. Russell. 1997. Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase Science 277: 1495-1497.
    • (1997) Science , vol.277 , pp. 1495-1497
    • Furnari, B.1    Rhind, N.2    Russell, P.3
  • 18
    • 0024266139 scopus 로고
    • New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
    • Gietz, R.D. and A. Sugino. 1988. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74: 527-534.
    • (1988) Gene , vol.74 , pp. 527-534
    • Gietz, R.D.1    Sugino, A.2
  • 19
    • 0029088371 scopus 로고
    • TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene
    • Greenwell, P.W., S.L. Kronmal, S.E. Porter, J. Gassenhuber, B. Obermaier, and T.D. Petes. 1995. TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82: 823-829.
    • (1995) Cell , vol.82 , pp. 823-829
    • Greenwell, P.W.1    Kronmal, S.L.2    Porter, S.E.3    Gassenhuber, J.4    Obermaier, B.5    Petes, T.D.6
  • 20
    • 0025821897 scopus 로고
    • A group of interacting yeast DNA replication genes
    • Hennessy, K.M., A. Lee, E. Chen, and D. Botstein. 1991. A group of interacting yeast DNA replication genes. Genes & Dev 5: 958-969.
    • (1991) Genes & Dev , vol.5 , pp. 958-969
    • Hennessy, K.M.1    Lee, A.2    Chen, E.3    Botstein, D.4
  • 21
    • 0030813561 scopus 로고    scopus 로고
    • Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae
    • Huang, M. and S.J. Elledge. 1997. Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae. Mol. Cell. Biol. 17: 6105-6113.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6105-6113
    • Huang, M.1    Elledge, S.J.2
  • 22
    • 0027192941 scopus 로고
    • Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein
    • Jackson, A.L., P.M. Pahl, K. Harrison, J. Rosamond, and R.A. Sclafani. 1993. Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein. Mol. Cell. Biol. 13: 2899-1908.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2899-2908
    • Jackson, A.L.1    Pahl, P.M.2    Harrison, K.3    Rosamond, J.4    Sclafani, R.A.5
  • 23
    • 0008124615 scopus 로고
    • Pulsed field gel electrophoresis
    • (ed. J.R. Johnston), Oxford University Press, Oxford, UK
    • Johnston, J.R. 1994. Pulsed field gel electrophoresis. In Molecular genetics of yeast: A practical approach. (ed. J.R. Johnston), pp. 83-95. Oxford University Press, Oxford, UK.
    • (1994) Molecular Genetics of Yeast: A Practical Approach , pp. 83-95
    • Johnston, J.R.1
  • 26
    • 0027971222 scopus 로고
    • An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae
    • Kato, R. and H. Ogawa. 1994. An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae. Nucleic. Acids Res. 22: 3104-3112.
    • (1994) Nucleic. Acids Res. , vol.22 , pp. 3104-3112
    • Kato, R.1    Ogawa, H.2
  • 27
    • 0029048775 scopus 로고
    • ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome
    • Liang, C., M. Weinreich, and B. Stillman. 1995. ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome. Cell 81: 667-676.
    • (1995) Cell , vol.81 , pp. 667-676
    • Liang, C.1    Weinreich, M.2    Stillman, B.3
  • 30
    • 0028880649 scopus 로고
    • Ataxia-telangiectasia and cellular responses to DNA damage
    • Meyn, M.S. 1995. Ataxia-telangiectasia and cellular responses to DNA damage. Cancer Res. 55: 5991-6001.
    • (1995) Cancer Res. , vol.55 , pp. 5991-6001
    • Meyn, M.S.1
  • 31
    • 0029150855 scopus 로고
    • TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
    • Morrow, D.M., D.A. Tagle, Y. Shiloh, F.S. Collins, and P. Hieter. 1995. TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell 82: 831-840.
    • (1995) Cell , vol.82 , pp. 831-840
    • Morrow, D.M.1    Tagle, D.A.2    Shiloh, Y.3    Collins, F.S.4    Hieter, P.5
  • 32
    • 0005583165 scopus 로고
    • The construction and use of cDNA libraries for genetic selections
    • (ed. J.R. Johnston), Oxford University Press, Oxford, UK
    • Mulligan, J.T. and S.J. Elledge. 1994. The construction and use of cDNA libraries for genetic selections. In Molecular genetics of yeast: A practical approach (ed. J.R. Johnston), pp. 65-81. Oxford University Press, Oxford, UK.
    • (1994) Molecular Genetics of Yeast: A Practical Approach , pp. 65-81
    • Mulligan, J.T.1    Elledge, S.J.2
  • 33
    • 0028945424 scopus 로고
    • A kinase from fission yeast responsible for blocking mitosis in S phase
    • Murakami, H. and H. Okayama. 1995. A kinase from fission yeast responsible for blocking mitosis in S phase. Nature 374: 817-819.
    • (1995) Nature , vol.374 , pp. 817-819
    • Murakami, H.1    Okayama, H.2
  • 34
    • 0028979332 scopus 로고
    • DNA polymerase ∈ links the DNA replicational machinery to the S phase checkpoint
    • Navas, T.A., Z. Zhou, and S.J. Elledge. 1995. DNA polymerase ∈ links the DNA replicational machinery to the S phase checkpoint. Cell 80: 29-39.
    • (1995) Cell , vol.80 , pp. 29-39
    • Navas, T.A.1    Zhou, Z.2    Elledge, S.J.3
  • 35
    • 0030912117 scopus 로고    scopus 로고
    • Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA
    • Pati, D., C. Keller, M. Groudine, and S.E. Plon. 1997. Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA. Mol. Cell Biol. 17: 3037-3046.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 3037-3046
    • Pati, D.1    Keller, C.2    Groudine, M.3    Plon, S.E.4
  • 36
    • 0030611095 scopus 로고    scopus 로고
    • Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
    • Peng, C.Y., P.R. Graves, R.S. Thoma, Z. Wu, A.S. Shaw, and H. Piwnica-Worms. 1997. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277: 1501-1505.
    • (1997) Science , vol.277 , pp. 1501-1505
    • Peng, C.Y.1    Graves, P.R.2    Thoma, R.S.3    Wu, Z.4    Shaw, A.S.5    Piwnica-Worms, H.6
  • 37
    • 0030593033 scopus 로고    scopus 로고
    • Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
    • Sanchez, Y., B.A. Desany, W. Jones, Q. Liu, B. Wang, and S.J. Elledge. 1996. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science 271: 357-360.
    • (1996) Science , vol.271 , pp. 357-360
    • Sanchez, Y.1    Desany, B.A.2    Jones, W.3    Liu, Q.4    Wang, B.5    Elledge, S.J.6
  • 38
    • 0030867582 scopus 로고    scopus 로고
    • Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
    • Sanchez, Y., C. Wong, R.S. Thomas, R. Richman, Z. Wu, H. Piwnica-Worms, and S.J. Elledge. 1997. Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25. Science 277: 1497-1501.
    • (1997) Science , vol.277 , pp. 1497-1501
    • Sanchez, Y.1    Wong, C.2    Thomas, R.S.3    Richman, R.4    Wu, Z.5    Piwnica-Worms, H.6    Elledge, S.J.7
  • 39
    • 0032497529 scopus 로고    scopus 로고
    • A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication
    • in press
    • Santocanale, S. and J.F.X. Diffley. 1998. A Mec1-and Rad53-dependent checkpoint controls late-firing origins of DNA replication. Nature (in press).
    • (1998) Nature
    • Santocanale, S.1    Diffley, J.F.X.2
  • 40
    • 0024669291 scopus 로고
    • A system of shuttle vectors and host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R.S. and P. Hieter. 1989. A system of shuttle vectors and host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 41
    • 0029928222 scopus 로고    scopus 로고
    • Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways
    • Sun, Z., D.S. Fay, F. Marini, and D.F. Stern. 1996. Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways. Genes &. Dev. 10: 395-406.
    • (1996) Genes &. Dev. , vol.10 , pp. 395-406
    • Sun, Z.1    Fay, D.S.2    Marini, F.3    Stern, D.F.4
  • 42
    • 0029664616 scopus 로고    scopus 로고
    • Rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint
    • Walworth, N. and R. Bernards. 1996. rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint. Science 271: 353-356.
    • (1996) Science , vol.271 , pp. 353-356
    • Walworth, N.1    Bernards, R.2
  • 43
    • 0027208148 scopus 로고
    • Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2
    • Walworth, N., S. Davey, and D. Beach. 1993. Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2. Nature 363: 368-371.
    • (1993) Nature , vol.363 , pp. 368-371
    • Walworth, N.1    Davey, S.2    Beach, D.3
  • 44
    • 0027212282 scopus 로고
    • Cell cycle arrest of cdc mutants and specificity of the RADX9, checkpoint
    • Weinen, T.A. and L.H. Hartwell. 1993. Cell cycle arrest of cdc mutants and specificity of the RADX9, checkpoint. Genetics 134: 63-80.
    • (1993) Genetics , vol.134 , pp. 63-80
    • Weinen, T.A.1    Hartwell, L.H.2
  • 45
    • 0028353634 scopus 로고
    • Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
    • Weinert, T.A., G.L. Kiser, and L.H. Hartwell. 1994. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes & Dev. 8: 652-665.
    • (1994) Genes & Dev. , vol.8 , pp. 652-665
    • Weinert, T.A.1    Kiser, G.L.2    Hartwell, L.H.3
  • 46
    • 0029844048 scopus 로고    scopus 로고
    • Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma
    • Xu, Y., T. Ashley, E.E. Brainerd, R.T. Bronson, M.S. Meyn, and D. Baltimore. 1996. Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Genes & Dev. 10: 2411-2422.
    • (1996) Genes & Dev. , vol.10 , pp. 2411-2422
    • Xu, Y.1    Ashley, T.2    Brainerd, E.E.3    Bronson, R.T.4    Meyn, M.S.5    Baltimore, D.6
  • 47
    • 0026651652 scopus 로고
    • Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae
    • Zhou, Z. and S.J. Elledge. 1992. Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae. Genetics 131: 851-866.
    • (1992) Genetics , vol.131 , pp. 851-866
    • Zhou, Z.1    Elledge, S.J.2
  • 48
    • 0027145127 scopus 로고
    • DUN1 encodes a protein kinase that controls the DNA damage response in yeast
    • _. 1993. DUN1 encodes a protein kinase that controls the DNA damage response in yeast. Cell 75: 1119-1127.
    • (1993) Cell , vol.75 , pp. 1119-1127


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.