Nek1 kinase associates with ATR-ATRIP and primes ATR for efficient DNA damage signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 6, 2013, Pages 2175-2180

  Liu, Shizhou ^a,b   Ho, Chu Kwen ^a   Ouyang, Jian ^a   Zou, Lee ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b CHINA MEDICAL UNIVERSITY   (China)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; ATRIP PROTEIN; DNA; NEK1 KINASE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CELL DAMAGE; CELL FUNCTION; CELL TYPE; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BASE SEQUENCE; CELL CYCLE PROTEINS; DNA DAMAGE; DNA-BINDING PROTEINS; GENE KNOCKDOWN TECHNIQUES; HCT116 CELLS; HEK293 CELLS; HUMANS; MULTIPROTEIN COMPLEXES; PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84873443175     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1217781110     Document Type: Article

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