메뉴 건너뛰기




Volumn 21, Issue 12, 2001, Pages 3913-3925

Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; MESYLIC ACID METHYL ESTER; PHOSPHATIDYLINOSITOL KINASE; PROTEIN MEC1; UNCLASSIFIED DRUG;

EID: 0035019655     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.12.3913-3925.2001     Document Type: Article
Times cited : (99)

References (64)
  • 1
    • 0024445751 scopus 로고
    • RADH, a gene of saccharomyces cerevisiae encoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene
    • Aboussekhra, A., R. Chanet, Z. Zgaga, C. Cassier-Chauvat, M. Heude, and F. Fabre. 1989. RADH, a gene of Saccharomyces cerevisiae encoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene. Nucleic Acids Res. 17:7211-7219.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 7211-7219
    • Aboussekhra, A.1    Chanet, R.2    Zgaga, Z.3    Cassier-Chauvat, C.4    Heude, M.5    Fabre, F.6
  • 2
    • 0027968012 scopus 로고
    • The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast
    • Alien, J. B., Z. Zhou, W. Siede, E. C. Friedberg, and S. J. Elledge. 1994. The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast. Genes Dev. 8:2416-2428.
    • (1994) Genes Dev. , vol.8 , pp. 2416-2428
    • Alien, J.B.1    Zhou, Z.2    Siede, W.3    Friedberg, E.C.4    Elledge, S.J.5
  • 5
    • 0030479885 scopus 로고    scopus 로고
    • The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast
    • Brush, G. S., D. M. Morrow, P. Hieter, and T. J. Kelly. 1996. The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast. Proc. Natl. Acad. Sci. USA 93:15075-15080.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 15075-15080
    • Brush, G.S.1    Morrow, D.M.2    Hieter, P.3    Kelly, T.J.4
  • 6
    • 0031044684 scopus 로고    scopus 로고
    • sp DNA structure checkpoint pathway
    • sp DNA structure checkpoint pathway. Curr. Opin. Genet. Dev. 7:93-98.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 93-98
    • Carr, A.M.1
  • 7
    • 0033579443 scopus 로고    scopus 로고
    • Yeast Sml 1, a protein inhibitor of ribonucleotide reductase
    • Chabes, A., V. Domkin, and L. Thelander. 1999. Yeast Sml 1, a protein inhibitor of ribonucleotide reductase. J. Biol. Chem. 274:36679-36683.
    • (1999) J. Biol. Chem. , vol.274 , pp. 36679-36683
    • Chabes, A.1    Domkin, V.2    Thelander, L.3
  • 8
    • 0033617368 scopus 로고    scopus 로고
    • Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl
    • Chen, G., et al. 1999. Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl. J. Biol. Chem. 274:12748-12752.
    • (1999) J. Biol. Chem. , vol.274 , pp. 12748-12752
    • Chen, G.1
  • 9
    • 0032472330 scopus 로고    scopus 로고
    • Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints
    • Cliby, W. A., C. J. Roberts, K. A. Cimprich, C. M. Stringer, J. R. Lamb, S. L. Schreiber, and S. H. Friend. 1998. Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints. EMBO J. 17:159-169.
    • (1998) EMBO J. , vol.17 , pp. 159-169
    • Cliby, W.A.1    Roberts, C.J.2    Cimprich, K.A.3    Stringer, C.M.4    Lamb, J.R.5    Schreiber, S.L.6    Friend, S.H.7
  • 10
    • 0031460633 scopus 로고    scopus 로고
    • The anaphase inhibitor of saccharomyces cerevisiae Pdslp is a target of the DNA damage checkpoint pathway
    • Cohen-Fix, O., and D. Koshland. 1997. The anaphase inhibitor of Saccharomyces cerevisiae Pdslp is a target of the DNA damage checkpoint pathway. Proc. Natl. Acad. Sci. USA 94:14361-14366.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14361-14366
    • Cohen-Fix, O.1    Koshland, D.2
  • 11
    • 0033527717 scopus 로고    scopus 로고
    • Requirement of ATM-dependent phosphorylation of Brca 1 in the DNA damage response to double-strand breaks
    • Cortez, D., Y. Wang, J. Quin, and S. J. Elledge. 1999. Requirement of ATM-dependent phosphorylation of Brca 1 in the DNA damage response to double-strand breaks. Science 286:1162-1166.
    • (1999) Science , vol.286 , pp. 1162-1166
    • Cortez, D.1    Wang, Y.2    Quin, J.3    Elledge, S.J.4
  • 13
    • 0032530824 scopus 로고    scopus 로고
    • Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway
    • Desany, B. A., A. A. Alcasabas, J. B. Bachant, and S. J. Elledge. 1998. Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes Dev. 12:2956-2970.
    • (1998) Genes Dev. , vol.12 , pp. 2956-2970
    • Desany, B.A.1    Alcasabas, A.A.2    Bachant, J.B.3    Elledge, S.J.4
  • 14
    • 0032133216 scopus 로고    scopus 로고
    • MEC1-dependent phosphorylation of Rad9p in response to DNA damage
    • Emili, A. 1998. MEC1-dependent phosphorylation of Rad9p in response to DNA damage. Mol. Cell 2:183-189.
    • (1998) Mol. Cell , vol.2 , pp. 183-189
    • Emili, A.1
  • 16
    • 0024266139 scopus 로고
    • New yeast-escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six base-pair restriction sites
    • Gietz, R. D., and A. Sugino. 1988. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six base-pair restriction sites. Gene 74:527-534.
    • (1988) Gene , vol.74 , pp. 527-534
    • Gietz, R.D.1    Sugino, A.2
  • 17
    • 0029088371 scopus 로고
    • TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene
    • Greenwell, P. W., S. L. Kronmal, S. E. Porter, J. Gassenhuber, B. Obermaier, and T. D. Petes. 1995. TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82:823-829.
    • (1995) Cell , vol.82 , pp. 823-829
    • Greenwell, P.W.1    Kronmal, S.L.2    Porter, S.E.3    Gassenhuber, J.4    Obermaier, B.5    Petes, T.D.6
  • 18
    • 0032822543 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choice
    • Grushcow, J. M., T. M. Holzen, K. J. Park, T. Weinert, M. Lichten, and D. K. Bishop. 1999. Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choice. Genetics 153:607-620.
    • (1999) Genetics , vol.153 , pp. 607-620
    • Grushcow, J.M.1    Holzen, T.M.2    Park, K.J.3    Weinert, T.4    Lichten, M.5    Bishop, D.K.6
  • 19
    • 0032864259 scopus 로고    scopus 로고
    • Many faces of ATM: Eighth international workshop on ataxia-telangiectasia
    • Halazonetis, T. D., and Y. Shiloh. 1999. Many faces of ATM: Eighth International Workshop on Ataxia-Telangiectasia. Biochim. Biophys. Acta 1424: R45-R55.
    • (1999) Biochim. Biophys. Acta , vol.1424
    • Halazonetis, T.D.1    Shiloh, Y.2
  • 20
    • 0029089618 scopus 로고
    • The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene
    • Hari, K. L., A. Santerre, J. J. Sekelsky, K. S. McKim, J. B. Boyd, and R. S. Hawley. 1995. The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene. Cell 82:815-821.
    • (1995) Cell , vol.82 , pp. 815-821
    • Hari, K.L.1    Santerre, A.2    Sekelsky, J.J.3    McKim, K.S.4    Boyd, J.B.5    Hawley, R.S.6
  • 21
    • 0028800996 scopus 로고
    • PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints
    • Keith, C. T., and S. L. Schreiber. 1995. PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints. Science 270:50-51.
    • (1995) Science , vol.270 , pp. 50-51
    • Keith, C.T.1    Schreiber, S.L.2
  • 22
    • 0032775010 scopus 로고    scopus 로고
    • Epitope tagging of yeast genes using a PCR-based strategy: More tags and improved practical routines
    • Knop, M., K. Siegers, G. Pereira, W. Zachariae, B. Winsor, K. Nasmyth, and E. Schiebel. 1999. Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines. Yeast 15:963-972.
    • (1999) Yeast , vol.15 , pp. 963-972
    • Knop, M.1    Siegers, K.2    Pereira, G.3    Zachariae, W.4    Winsor, B.5    Nasmyth, K.6    Schiebel, E.7
  • 23
    • 0032962928 scopus 로고    scopus 로고
    • Role of a complex containing Rad17, Mec3, and Ddcl in the yeast DNA damage checkpoint pathway
    • Kondo, T., K. Matsumoto, and K. Sugimoto. 1999. Role of a complex containing Rad17, Mec3, and Ddcl in the yeast DNA damage checkpoint pathway. Mol. Cell. Biol. 19:1136-1143.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1136-1143
    • Kondo, T.1    Matsumoto, K.2    Sugimoto, K.3
  • 24
    • 0034644220 scopus 로고    scopus 로고
    • Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response
    • Li, S., N. S. Y. Ting, L. Zheng, P.-L. Chen, Y. Ziv, Y. Shiloh, E. Y.-H. P. Lee, and W.-H. Lee. 2000. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature 406:210-215.
    • (2000) Nature , vol.406 , pp. 210-215
    • Li, S.1    Ting, N.S.Y.2    Zheng, L.3    Chen, P.-L.4    Ziv, Y.5    Shiloh, Y.6    Lee, E.Y.-H.P.7    Lee, W.-H.8
  • 25
    • 0034665462 scopus 로고    scopus 로고
    • Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity
    • Liberi, G., I. Chiolo, A. Pellicioli, M. Lopes, P. Plevani, M. Muzi-Falconi, and M. Foiani. 2000. Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity. EMBO J. 19:5027-5038.
    • (2000) EMBO J. , vol.19 , pp. 5027-5038
    • Liberi, G.1    Chiolo, I.2    Pellicioli, A.3    Lopes, M.4    Plevani, P.5    Muzi-Falconi, M.6    Foiani, M.7
  • 28
    • 0033870408 scopus 로고    scopus 로고
    • Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast
    • Longhese, M. P., V. Paciotti, H. Neecke, and G. Lucchini. 2000. Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. Genetics 155:1577-1591.
    • (2000) Genetics , vol.155 , pp. 1577-1591
    • Longhese, M.P.1    Paciotti, V.2    Neecke, H.3    Lucchini, G.4
  • 29
    • 0030804309 scopus 로고    scopus 로고
    • The novel DNA damage checkpoint protein ddclp is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast
    • Longhese, M. P., V. Paciotti, R. Fraschini, P. Plevani, and G. Lucchini. 1997. The novel DNA damage checkpoint protein Ddclp is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast. EMBO J. 16:5216-5226.
    • (1997) EMBO J. , vol.16 , pp. 5216-5226
    • Longhese, M.P.1    Paciotti, V.2    Fraschini, R.3    Plevani, P.4    Lucchini, G.5
  • 31
    • 0034610290 scopus 로고    scopus 로고
    • Protein kinase activity of Tel1p and Mec1p, two saccharomyces cerevisiae proteins related to the human ATM protein kinase
    • Mallory, J. C., and T. D. Petes. 2000. Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. Proc. Natl. Acad. Sci. USA 97:13749-13754.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13749-13754
    • Mallory, J.C.1    Petes, T.D.2
  • 32
    • 0027306104 scopus 로고
    • High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia
    • Meyn, M. S. 1993. High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia. Science 260:1327-1330.
    • (1993) Science , vol.260 , pp. 1327-1330
    • Meyn, M.S.1
  • 33
    • 0034141562 scopus 로고    scopus 로고
    • The controlling role of ATM in homologous recombinational repair of DNA damage
    • Morrison, C., E. Sonoda, N. Takao, A. Shinohara, K. Yamamoto, and S. Takeda. 2000. The controlling role of ATM in homologous recombinational repair of DNA damage. EMBO J. 19:463-471.
    • (2000) EMBO J. , vol.19 , pp. 463-471
    • Morrison, C.1    Sonoda, E.2    Takao, N.3    Shinohara, A.4    Yamamoto, K.5    Takeda, S.6
  • 34
    • 0029150855 scopus 로고
    • TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
    • Morrow, D. M., D. A. Tagle, Y. Shiloh, F. S. Collins, and P. Hieter. 1995. TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell 82:831-840.
    • (1995) Cell , vol.82 , pp. 831-840
    • Morrow, D.M.1    Tagle, D.A.2    Shiloh, Y.3    Collins, F.S.4    Hieter, P.5
  • 35
    • 0032527776 scopus 로고    scopus 로고
    • Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddclp, which physically interacts with Mec3p
    • Paciotti, V., G. Lucchini, P. Plevani, and M. P. Longhese. 1998. Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddclp, which physically interacts with Mec3p. EMBO J. 17:101-111.
    • (1998) EMBO J. , vol.17 , pp. 101-111
    • Paciotti, V.1    Lucchini, G.2    Plevani, P.3    Longhese, M.P.4
  • 36
    • 0034663809 scopus 로고    scopus 로고
    • The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast
    • Paciotti, V., M. Clerici, G. Lucchini, and M. P. Longhese. 2000. The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. Genes Dev. 14:2046-2059.
    • (2000) Genes Dev. , vol.14 , pp. 2046-2059
    • Paciotti, V.1    Clerici, M.2    Lucchini, G.3    Longhese, M.P.4
  • 37
    • 1842366037 scopus 로고    scopus 로고
    • Two pathways for removal of nonhomologous DNA ends during double-strand break repair in saccharomyces cerevisiae
    • Paques, F., and J. E. Haber. 1997. Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae. Mol. Cell. Biol. 17:6765-6771.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6765-6771
    • Paques, F.1    Haber, J.E.2
  • 38
    • 0029085781 scopus 로고
    • A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage
    • Paulovich, A. G., and L. H. Hartwell. 1995. A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell 82:841-847.
    • (1995) Cell , vol.82 , pp. 841-847
    • Paulovich, A.G.1    Hartwell, L.H.2
  • 40
    • 0029976805 scopus 로고    scopus 로고
    • The use of dominant-negative mutations to elucidate signal transduction pathways in lymphocytes
    • Perlmutter, R. M., and I. J. Alberola. 1996. The use of dominant-negative mutations to elucidate signal transduction pathways in lymphocytes. Curr. Opin. Immunol. 8:285-290.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 285-290
    • Perlmutter, R.M.1    Alberola, I.J.2
  • 42
    • 0034329474 scopus 로고    scopus 로고
    • LCD1: An essential gene involved in checkpoint control and regulation of the MEC1 signaling pathway in saccharomyces cerevisiae
    • Rouse, J., and S. P. Jackson. 2000. LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signaling pathway in Saccharomyces cerevisiae. EMBO J. 19:5801-5812.
    • (2000) EMBO J. , vol.19 , pp. 5801-5812
    • Rouse, J.1    Jackson, S.P.2
  • 43
    • 0030593033 scopus 로고    scopus 로고
    • Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
    • Sanchez, Y., B. A. Desany, W. J. Jones, Q. Liu, B. Wang, and S. J. Elledge. 1996. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science 271:357-360.
    • (1996) Science , vol.271 , pp. 357-360
    • Sanchez, Y.1    Desany, B.A.2    Jones, W.J.3    Liu, Q.4    Wang, B.5    Elledge, S.J.6
  • 44
    • 0033527787 scopus 로고    scopus 로고
    • Control of the DNA damage checkpoint by Chk1 and Rad53 protein kinases through distinct mechanisms
    • Sanchez, Y., J. Bachant, H. Wang, F. H. Hu, D. Liu, M. Tezlaff, and S. J. Elledge. 1999. Control of the DNA damage checkpoint by Chk1 and Rad53 protein kinases through distinct mechanisms. Science 286:1166-1171.
    • (1999) Science , vol.286 , pp. 1166-1171
    • Sanchez, Y.1    Bachant, J.2    Wang, H.3    Hu, F.H.4    Liu, D.5    Tezlaff, M.6    Elledge, S.J.7
  • 45
    • 0029057336 scopus 로고
    • A single ataxia telangiectasia gene with a product similar to PI-3 kinase
    • Savitsky, K., et al. 1995. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 286:1749-1753.
    • (1995) Science , vol.286 , pp. 1749-1753
    • Savitsky, K.1
  • 46
    • 0030992749 scopus 로고    scopus 로고
    • Interaction between ATM protein and c-Abl in response to DNA damage
    • Shafman, T., et al. 1997. Interaction between ATM protein and c-Abl in response to DNA damage. Nature 387:520-523.
    • (1997) Nature , vol.387 , pp. 520-523
    • Shafman, T.1
  • 47
    • 0027338038 scopus 로고
    • 1 arrest defines a second checkpoint for damaged DNA in the cell cycle of saccharomyces cerevisiae
    • 1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 90:7985-7989.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7985-7989
    • Siede, W.1    Friedberg, A.S.2    Friedberg, E.C.3
  • 48
    • 0029928222 scopus 로고    scopus 로고
    • Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways
    • Sun, Z., D. S. Fay, F. Marini, M. Foiani, and D. F. Stern. 1996. Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways. Genes Dev. 10:395-406.
    • (1996) Genes Dev. , vol.10 , pp. 395-406
    • Sun, Z.1    Fay, D.S.2    Marini, F.3    Foiani, M.4    Stern, D.F.5
  • 49
    • 0032504069 scopus 로고    scopus 로고
    • Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint
    • Sun, Z., J. Hsiao, D. S. Fay, and D. F. Stern. 1998. Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint. Science 281:272-274.
    • (1998) Science , vol.281 , pp. 272-274
    • Sun, Z.1    Hsiao, J.2    Fay, D.S.3    Stern, D.F.4
  • 50
    • 0033582906 scopus 로고    scopus 로고
    • A sliding clamp model for the Rad 1 family of cell cycle checkpoint proteins
    • Thelen, M. P., C. Venclovas, and K. Fidelis. 1999. A sliding clamp model for the Rad 1 family of cell cycle checkpoint proteins. Cell 96:769-770.
    • (1999) Cell , vol.96 , pp. 769-770
    • Thelen, M.P.1    Venclovas, C.2    Fidelis, K.3
  • 51
    • 0032820031 scopus 로고    scopus 로고
    • Genetic control of recombination partner preference in yeast meiosis: Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination
    • Thompson, D. A., and F. W. Stahl. 1999. Genetic control of recombination partner preference in yeast meiosis: isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination. Genetics 153:621-641.
    • (1999) Genetics , vol.153 , pp. 621-641
    • Thompson, D.A.1    Stahl, F.W.2
  • 52
    • 0031960691 scopus 로고    scopus 로고
    • Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism
    • Umezu, K., N. Sugawara, C. Chen, J. E. Haber, and R. D. Kolodner. 1998. Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics 148:989-1005.
    • (1998) Genetics , vol.148 , pp. 989-1005
    • Umezu, K.1    Sugawara, N.2    Chen, C.3    Haber, J.E.4    Kolodner, R.D.5
  • 53
    • 0032189952 scopus 로고    scopus 로고
    • The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tell-dependent hyperphosphorylation and interacts with Rad53 after DNA damage
    • Vialard, J. E., C. S. Gilbert, C. M. Green, and N. F. Lowndes. 1998. The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tell-dependent hyperphosphorylation and interacts with Rad53 after DNA damage. EMBO J. 17:5679-5688.
    • (1998) EMBO J. , vol.17 , pp. 5679-5688
    • Vialard, J.E.1    Gilbert, C.S.2    Green, C.M.3    Lowndes, N.F.4
  • 54
    • 0028676232 scopus 로고
    • New heterologous modules for classical or PCR-based gene disruption in saccharomyces cerevisiae
    • Wach, A., A. Brachat, R. Pohlmann, and P. Philippsen. 1994. New heterologous modules for classical or PCR-based gene disruption in Saccharomyces cerevisiae. Yeast 10:1793-1808.
    • (1994) Yeast , vol.10 , pp. 1793-1808
    • Wach, A.1    Brachat, A.2    Pohlmann, R.3    Philippsen, P.4
  • 55
    • 0031663505 scopus 로고    scopus 로고
    • The DNA replication fork in eukaryotic cells
    • Waga, S., and B. Stillman. 1998. The DNA replication fork in eukaryotic cells. Annu. Rev. Biochem. 67:721-751.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 721-751
    • Waga, S.1    Stillman, B.2
  • 56
    • 0030988654 scopus 로고    scopus 로고
    • Yeast checkpoint controls and relevance to cancer
    • Weinert, T. 1997. Yeast checkpoint controls and relevance to cancer. Cancer Surv. 29:109-132.
    • (1997) Cancer Surv. , vol.29 , pp. 109-132
    • Weinert, T.1
  • 57
    • 0032483562 scopus 로고    scopus 로고
    • DNA damage and checkpoint pathways: Molecular anatomy and interactions with repair
    • Weinert, T. 1998. DNA damage and checkpoint pathways: molecular anatomy and interactions with repair. Cell 94:555-558.
    • (1998) Cell , vol.94 , pp. 555-558
    • Weinert, T.1
  • 58
    • 0023712476 scopus 로고
    • The RAD9 gene controls the cell cycle response to DNA damage in saccharomyces cerevisiae
    • Weinert, T. A., and L. H. Hartwell. 1988. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241: 317-322.
    • (1988) Science , vol.241 , pp. 317-322
    • Weinert, T.A.1    Hartwell, L.H.2
  • 59
    • 0027212282 scopus 로고
    • Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint
    • Weinert, T. A., and L. H. Hartwell. 1993. Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint. Genetics 134:63-80.
    • (1993) Genetics , vol.134 , pp. 63-80
    • Weinert, T.A.1    Hartwell, L.H.2
  • 60
    • 0028353634 scopus 로고
    • Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
    • Weinert, T. A., G. L. Kiser, and L. H. Hartwell. 1994. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev. 8:652-665.
    • (1994) Genes Dev. , vol.8 , pp. 652-665
    • Weinert, T.A.1    Kiser, G.L.2    Hartwell, L.H.3
  • 62
    • 0029127643 scopus 로고
    • ATM-related genes: What do they tell us about functions of the human gene?
    • Zakian, V. A. 1995. ATM-related genes: what do they tell us about functions of the human gene? Cell 82:685-687.
    • (1995) Cell , vol.82 , pp. 685-687
    • Zakian, V.A.1
  • 63
    • 0034713393 scopus 로고    scopus 로고
    • Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products
    • Zhao, S., Y. C. Weng, S.-S. F. Yuan, Y.-T. Lin, H.-C. Hsu, S.-C. J. Lin, et al. 2000. Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products. Nature 405:473-477.
    • (2000) Nature , vol.405 , pp. 473-477
    • Zhao, S.1    Weng, Y.C.2    Yuan, S.-S.F.3    Lin, Y.-T.4    Hsu, H.-C.5    Lin, S.-C.J.6
  • 64
    • 0032161269 scopus 로고    scopus 로고
    • A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools
    • Zhao, X., E. G. D. Muller, and R. Rothstein. 1998. A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools. Mol. Cell 2:329-340.
    • (1998) Mol. Cell , vol.2 , pp. 329-340
    • Zhao, X.1    Muller, E.G.D.2    Rothstein, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.