Erratum: A Mechanism for Controlled Breakage of Under-replicated Chromosomes during Mitosis (Developmental Cell (2016) 39(6) (740–755)(S1534580716308292)(10.1016/j.devcel.2016.11.017));A Mechanism for Controlled Breakage of Under-replicated Chromosomes during Mitosis

Developmental Cell

Volumn 39, Issue 6, 2016, Pages 740-755

  Duda, Heike ^a   Arter, Meret ^a   Gloggnitzer, Jiradet ^a   Teloni, Federico ^b   Wild, Philipp ^a   Blanco, Miguel G ^c   Altmeyer, Matthias ^b   Matos, Joao ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c Universidade de Santiago de Compostela and Instituto de Investigación Sanitaria de Santiago de Compostela   (Spain)

Author keywords

CDK1; cell cycle; chromosome pulverization; DNA replication; EME2; MUS81; PLK1; SLX4; WEE1

Indexed keywords

CYCLIN DEPENDENT KINASE 1; ENDONUCLEASE; MUS81 NUCLEASE; NUCLEASE; POLO LIKE KINASE 1; PROTEIN KINASE; SCAFFOLD PROTEIN; SLX4 PROTEIN; UNCLASSIFIED DRUG; WEE1 KINASE; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; MUS81 PROTEIN, HUMAN; PROTEIN BINDING; RECOMBINASE; SLX4 PROTEIN, HUMAN;

ARTICLE; CELL CYCLE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CHROMOSOME; CHROMOSOME REPLICATION; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA REPLICATION; DNA STRAND BREAKAGE; ENZYME ACTIVITY; ENZYME SUBSTRATE; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOSIS; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; BIOLOGICAL MODEL; CELL DEATH; CELL SURVIVAL; DNA DAMAGE; DNA FRAGMENTATION; HUMAN CHROMOSOME; METABOLISM; PHOSPHORYLATION;

CDC2 PROTEIN KINASE; CELL CYCLE PROTEINS; CELL DEATH; CELL SURVIVAL; CHROMOSOMES, HUMAN; DNA DAMAGE; DNA FRAGMENTATION; DNA REPLICATION; DNA-BINDING PROTEINS; ENDONUCLEASES; HELA CELLS; HUMANS; MITOSIS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN BINDING; RECOMBINASES; S PHASE;

EID: 85006355436     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2017.02.015     Document Type: Erratum

References (53)

1. Aarts, M., Sharpe, R., Garcia-Murillas, I., Gevensleben, H., Hurd, M.S., Shumway, S.D., Toniatti, C., Ashworth, A., Turner, N.C., Forced mitotic entry of S-phase cells as a therapeutic strategy induced by inhibition of WEE1. Cancer Discov. 2 (2012), 524–539.
2. Beck, H., Nahse, V., Larsen, M.S., Groth, P., Clancy, T., Lees, M., Jorgensen, M., Helleday, T., Syljuasen, R.G., Sorensen, C.S., Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase. J. Cell Biol. 188 (2010), 629–638.
3. Beck, H., Nahse-Kumpf, V., Larsen, M.S., O'Hanlon, K.A., Patzke, S., Holmberg, C., Mejlvang, J., Groth, A., Nielsen, O., Syljuasen, R.G., et al. Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption. Mol. Cell. Biol. 32 (2012), 4226–4236.
4. Castor, D., Nair, N., Declais, A.C., Lachaud, C., Toth, R., Macartney, T.J., Lilley, D.M., Arthur, J.S., Rouse, J., Cooperative control of Holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases. Mol. Cell 52 (2013), 221–233.
5. Coudreuse, D., Nurse, P., Driving the cell cycle with a minimal CDK control network. Nature 468 (2010), 1074–1079.
6. Crasta, K., Ganem, N.J., Dagher, R., Lantermann, A.B., Ivanova, E.V., Pan, Y., Nezi, L., Protopopov, A., Chowdhury, D., Pellman, D., DNA breaks and chromosome pulverization from errors in mitosis. Nature 482 (2012), 53–58.
7. Dominguez-Kelly, R., Martin, Y., Koundrioukoff, S., Tanenbaum, M.E., Smits, V.A., Medema, R.H., Debatisse, M., Freire, R., Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease. J. Cell Biol. 194 (2011), 567–579.
8. Enoch, T., Nurse, P., Coupling M phase and S phase: controls maintaining the dependence of mitosis on chromosome replication. Cell 65 (1991), 921–923.
9. Eykelenboom, J.K., Harte, E.C., Canavan, L., Pastor-Peidro, A., Calvo-Asensio, I., Llorens-Agost, M., Lowndes, N.F., ATR activates the S-M checkpoint during unperturbed growth to ensure sufficient replication prior to mitotic onset. Cell Rep. 5 (2013), 1095–1107.
10. Fekairi, S., Scaglione, S., Chahwan, C., Taylor, E.R., Tissier, A., Coulon, S., Dong, M.Q., Ruse, C., Yates, J.R. 3rd, Russell, P., et al. Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases. Cell 138 (2009), 78–89.
11. Forment, J.V., Blasius, M., Guerini, I., Jackson, S.P., Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation. PLoS One, 6, 2011, e23517.
12. Forment, J.V., Kaidi, A., Jackson, S.P., Chromothripsis and cancer: causes and consequences of chromosome shattering. Nat. Rev. Cancer 12 (2012), 663–670.
13. Gallo-Fernandez, M., Saugar, I., Ortiz-Bazan, M.A., Vazquez, M.V., Tercero, J.A., Cell cycle-dependent regulation of the nuclease activity of Mus81-Eme1/Mms4. Nucleic Acids Res. 40 (2012), 8325–8335.
14. Gritenaite, D., Princz, L.N., Szakal, B., Bantele, S.C., Wendeler, L., Schilbach, S., Habermann, B.H., Matos, J., Lisby, M., Branzei, D., et al. A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication. Genes Dev. 28 (2014), 1604–1619.
15. Guervilly, J.H., Takedachi, A., Naim, V., Scaglione, S., Chawhan, C., Lovera, Y., Despras, E., Kuraoka, I., Kannouche, P., Rosselli, F., et al. The SLX4 complex is a SUMO E3 ligase that impacts on replication stress outcome and genome stability. Mol. Cell 57 (2015), 123–137.
16. Hanada, K., Budzowska, M., Davies, S.L., van Drunen, E., Onizawa, H., Beverloo, H.B., Maas, A., Essers, J., Hickson, I.D., Kanaar, R., The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks. Nat. Struct. Mol. Biol. 14 (2007), 1096–1104.
17. Hartwell, L.H., Weinert, T.A., Checkpoints: controls that ensure the order of cell cycle events. Science 246 (1989), 629–634.
18. Heald, R., McLoughlin, M., McKeon, F., Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase. Cell 74 (1993), 463–474.
19. Hirai, H., Iwasawa, Y., Okada, M., Arai, T., Nishibata, T., Kobayashi, M., Kimura, T., Kaneko, N., Ohtani, J., Yamanaka, K., et al. Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents. Mol. Cancer Ther. 8 (2009), 2992–3000.
20. Jackson, S.P., Bartek, J., The DNA-damage response in human biology and disease. Nature 461 (2009), 1071–1078.
21. Jin, P., Hardy, S., Morgan, D.O., Nuclear localization of cyclin B1 controls mitotic entry after DNA damage. J. Cell Biol. 141 (1998), 875–885.
22. Kim, Y., Spitz, G.S., Veturi, U., Lach, F.P., Auerbach, A.D., Smogorzewska, A., Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4. Blood 121 (2013), 54–63.
23. Lee, K.S., Burke, T.R. Jr., Park, J.E., Bang, J.K., Lee, E., Recent advances and new strategies in targeting Plk1 for anticancer therapy. Trends Pharmacol. Sci. 36 (2015), 858–877.
24. Liu, P., Erez, A., Nagamani, S.C., Dhar, S.U., Kolodziejska, K.E., Dharmadhikari, A.V., Cooper, M.L., Wiszniewska, J., Zhang, F., Withers, M.A., et al. Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell 146 (2011), 889–903.
25. Magiera, M.M., Gueydon, E., Schwob, E., DNA replication and spindle checkpoints cooperate during S phase to delay mitosis and preserve genome integrity. J. Cell Biol. 204 (2014), 165–175.
26. Malumbres, M., Barbacid, M., Cell cycle, CDKs and cancer: a changing paradigm. Nat. Rev. Cancer 9 (2009), 153–166.
27. Mankouri, H.W., Huttner, D., Hickson, I.D., How unfinished business from S-phase affects mitosis and beyond. EMBO J. 32 (2013), 2661–2671.
28. Matos, J., Blanco, M.G., Maslen, S., Skehel, J.M., West, S.C., Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis. Cell 147 (2011), 158–172.
29. Matos, J., Blanco, M.G., West, S.C., Cell-cycle kinases coordinate the resolution of recombination intermediates with chromosome segregation. Cell Rep. 4 (2013), 76–86.
30. Minocherhomji, S., Ying, S., Bjerregaard, V.A., Bursomanno, S., Aleliunaite, A., Wu, W., Mankouri, H.W., Shen, H., Liu, Y., Hickson, I.D., Replication stress activates DNA repair synthesis in mitosis. Nature 528 (2015), 286–290.
31. Moore, J.D., Kirk, J.A., Hunt, T., Unmasking the S-phase-promoting potential of cyclin B1. Science 300 (2003), 987–990.
32. Munoz, I.M., Hain, K., Declais, A.C., Gardiner, M., Toh, G.W., Sanchez-Pulido, L., Heuckmann, J.M., Toth, R., Macartney, T., Eppink, B., et al. Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. Mol. Cell 35 (2009), 116–127.
33. Nagata, S., Nagase, H., Kawane, K., Mukae, N., Fukuyama, H., Degradation of chromosomal DNA during apoptosis. Cell Death Differ. 10 (2003), 108–116.
34. Naim, V., Wilhelm, T., Debatisse, M., Rosselli, F., ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis. Nat. Cell Biol. 15 (2013), 1008–1015.
35. Nasmyth, K., Evolution of the cell cycle. Philos. Trans. R. Soc. Lond. B Biol. Sci. 349 (1995), 271–281.
36. Neelsen, K.J., Zanini, I.M., Herrador, R., Lopes, M., Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates. J. Cell Biol. 200 (2013), 699–708.
37. Pedersen, R.T., Kruse, T., Nilsson, J., Oestergaard, V.H., Lisby, M., TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells. J. Cell Biol. 210 (2015), 565–582.
38. Pepe, A., West, S.C., MUS81-EME2 promotes replication fork restart. Cell Rep. 7 (2014), 1048–1055.
39. Pepe, A., West, S.C., Substrate specificity of the MUS81-EME2 structure selective endonuclease. Nucleic Acids Res. 42 (2014), 3833–3845.
40. Peters, J.M., King, R.W., Hoog, C., Kirschner, M.W., Identification of BIME as a subunit of the anaphase-promoting complex. Science 274 (1996), 1199–1201.
41. Pines, J., Four-dimensional control of the cell cycle. Nat. Cell Biol. 1 (1999), E73–E79.
42. Russell, P., Nurse, P., Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog. Cell 49 (1987), 559–567.
43. Schmitz, M.H., Held, M., Janssens, V., Hutchins, J.R., Hudecz, O., Ivanova, E., Goris, J., Trinkle-Mulcahy, L., Lamond, A.I., Poser, I., et al. Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells. Nat. Cell Biol. 12 (2010), 886–893.
44. Stephens, P.J., Greenman, C.D., Fu, B., Yang, F., Bignell, G.R., Mudie, L.J., Pleasance, E.D., Lau, K.W., Beare, D., Stebbings, L.A., et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144 (2011), 27–40.
45. Stern, B., Nurse, P., A quantitative model for the cdc2 control of S phase and mitosis in fission yeast. Trends Genet. 12 (1996), 345–350.
46. Svendsen, J.M., Smogorzewska, A., Sowa, M.E., O'Connell, B.C., Gygi, S.P., Elledge, S.J., Harper, J.W., Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Cell 138 (2009), 63–77.
47. Szakal, B., Branzei, D., Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover. EMBO J. 32 (2013), 1155–1167.
48. Techer, H., Koundrioukoff, S., Carignon, S., Wilhelm, T., Millot, G.A., Lopez, B.S., Brison, O., Debatisse, M., Signaling from Mus81-Eme2-Dependent DNA damage elicited by Chk1 deficiency modulates replication fork speed and origin usage. Cell Rep. 14 (2016), 1114–1127.
49. Toledo, L.I., Altmeyer, M., Rask, M.B., Lukas, C., Larsen, D.H., Povlsen, L.K., Bekker-Jensen, S., Mailand, N., Bartek, J., Lukas, J., ATR prohibits replication catastrophe by preventing global exhaustion of RPA. Cell 155 (2013), 1088–1103.
50. Wild, P., Matos, J., Cell cycle control of DNA joint molecule resolution. Curr. Opin. Cell Biol. 40 (2016), 74–80.
51. Wyatt, H.D., Sarbajna, S., Matos, J., West, S.C., Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells. Mol. Cell 52 (2013), 234–247.
52. Ying, S., Minocherhomji, S., Chan, K.L., Palmai-Pallag, T., Chu, W.K., Wass, T., Mankouri, H.W., Liu, Y., Hickson, I.D., MUS81 promotes common fragile site expression. Nat. Cell Biol. 15 (2013), 1001–1007.
53. Zhou, B.B., Elledge, S.J., The DNA damage response: putting checkpoints in perspective. Nature 408 (2000), 433–439.