Moonlighting at replication forks – a new life for homologous recombination proteins BRCA1, BRCA2 and RAD51

FEBS Letters

Volumn 591, Issue 8, 2017, Pages 1083-1100

  Kolinjivadi, Arun Mouli ^a   Sannino, Vincenzo ^a   de Antoni, Anna ^a   Técher, Hervé ^a   Baldi, Giorgio ^a   Costanzo, Vincenzo ^a  

^a FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

Author keywords

DNA recombination; DNA replication; genome stability

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DEOXYRIBONUCLEASE; DOUBLE STRANDED DNA; MRE11 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEPTIDES AND PROTEINS; RAD51 PROTEIN; RECA PROTEIN; REPLICATION FACTOR; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; BRCA1 PROTEIN, HUMAN; BRCA2 PROTEIN, HUMAN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; DNA LIGASE; MRE11A PROTEIN, HUMAN; NBN PROTEIN, HUMAN; NUCLEAR PROTEIN; RAD50 PROTEIN, HUMAN; RAD51 PROTEIN, HUMAN; REPLICATION FACTOR A;

CANCER CELL; CANCER CHEMOTHERAPY; CELL VIABILITY; DNA DEGRADATION; DNA REPAIR; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; EGG EXTRACT; ENZYME REPRESSION; EUKARYOTE; HOMOLOGOUS RECOMBINATION; HUMAN; MOLECULAR INTERACTION; MUTATIONAL ANALYSIS; NONHUMAN; PROKARYOTE; PROTEIN FUNCTION; REVIEW; XENOPUS LAEVIS; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; CHEMISTRY; CHROMOSOMAL INSTABILITY; DNA STRAND BREAKAGE; METABOLISM; PROTEIN MULTIMERIZATION;

ANIMALS; BRCA1 PROTEIN; BRCA2 PROTEIN; CELL CYCLE PROTEINS; CHROMOSOMAL INSTABILITY; DNA BREAKS; DNA REPAIR ENZYMES; DNA REPLICATION; DNA-BINDING PROTEINS; HOMOLOGOUS RECOMBINATION; HUMANS; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; PROTEIN MULTIMERIZATION; RAD51 RECOMBINASE; REPLICATION PROTEIN A;

EID: 85011290982     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1002/1873-3468.12556     Document Type: Review

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