-
1
-
-
78649747039
-
Body-mass index and mortality among 1.46 million white adults
-
Berrington de Gonzalez A, Hartge P, Cerhan JR, Flint AJ, Hannan L, MacInnis RJ, Moore SC, Tobias GS, Anton-Culver H, Freeman LB, Beeson WL, Clipp SL, English DR, Folsom AR, Freedman DM, Giles G, Hakansson N, Henderson KD, Hoffman-Bolton J, Hoppin JA, Koenig KL, Lee I-M, Linet MS, Park Y, Pocobelli G, Schatzkin A, Sesso HD, Weiderpass E, Willcox BJ, Wolk A, Zeleniuch-Jacquotte A, Willett WC, Thun MJ. Body-mass index and mortality among 1.46 million white adults. N Engl J Med. 2010;363(23):2211-2219.
-
(2010)
N Engl J Med
, vol.363
, Issue.23
, pp. 2211-2219
-
-
Berrington de Gonzalez, A.1
Hartge, P.2
Cerhan, J.R.3
Flint, A.J.4
Hannan, L.5
MacInnis, R.J.6
Moore, S.C.7
Tobias, G.S.8
Anton-Culver, H.9
Freeman, L.B.10
Beeson, W.L.11
Clipp, S.L.12
English, D.R.13
Folsom, A.R.14
Freedman, D.M.15
Giles, G.16
Hakansson, N.17
Henderson, K.D.18
Hoffman-Bolton, J.19
Hoppin, J.A.20
Koenig, K.L.21
Lee, I.-M.22
Linet, M.S.23
Park, Y.24
Pocobelli, G.25
Schatzkin, A.26
Sesso, H.D.27
Weiderpass, E.28
Willcox, B.J.29
Wolk, A.30
Zeleniuch-Jacquotte, A.31
Willett, W.C.32
Thun, M.J.33
more..
-
2
-
-
84881221754
-
Recruited brown adipose tissue as an antiobesity agent in humans
-
Yoneshiro T, Aita S, Matsushita M, Kayahara T, Kameya T, Kawai Y, Iwanaga T, Saito M. Recruited brown adipose tissue as an antiobesity agent in humans. J Clin Invest. 2013;123(8):3404-3408.
-
(2013)
J Clin Invest
, vol.123
, Issue.8
, pp. 3404-3408
-
-
Yoneshiro, T.1
Aita, S.2
Matsushita, M.3
Kayahara, T.4
Kameya, T.5
Kawai, Y.6
Iwanaga, T.7
Saito, M.8
-
3
-
-
82555186955
-
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
-
Nguyen KD, Qiu Y, Cui X, Goh YPS, Mwangi J, David T, Mukundan L, Brombacher F, Locksley RM, Chawla A. Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis. Nature. 2011;480(7375):104-108.
-
(2011)
Nature
, vol.480
, Issue.7375
, pp. 104-108
-
-
Nguyen, K.D.1
Qiu, Y.2
Cui, X.3
Goh, Y.P.S.4
Mwangi, J.5
David, T.6
Mukundan, L.7
Brombacher, F.8
Locksley, R.M.9
Chawla, A.10
-
4
-
-
84920940721
-
Activated type 2 innate lymphoid cells regulate beige fat biogenesis
-
Lee M-W, Odegaard JI, Mukundan L, Qiu Y, Molofsky AB, Nussbaum JC, Yun K, Locksley RM, Chawla A. Activated type 2 innate lymphoid cells regulate beige fat biogenesis. Cell. 2015; 160(1-2):74-87.
-
(2015)
Cell
, vol.160
, Issue.1-2
, pp. 74-87
-
-
Lee, M.-W.1
Odegaard, J.I.2
Mukundan, L.3
Qiu, Y.4
Molofsky, A.B.5
Nussbaum, J.C.6
Yun, K.7
Locksley, R.M.8
Chawla, A.9
-
5
-
-
84902094655
-
Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat
-
Qiu Y, Nguyen KD, Odegaard JI, Cui X, Tian X, Locksley RM, Palmiter RD, Chawla A. Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat. Cell. 2014;157(6):1292-1308.
-
(2014)
Cell
, vol.157
, Issue.6
, pp. 1292-1308
-
-
Qiu, Y.1
Nguyen, K.D.2
Odegaard, J.I.3
Cui, X.4
Tian, X.5
Locksley, R.M.6
Palmiter, R.D.7
Chawla, A.8
-
6
-
-
84924969384
-
Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity
-
Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P, Artis D. Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity. Nature. 2014;519(7542):242-246.
-
(2014)
Nature
, vol.519
, Issue.7542
, pp. 242-246
-
-
Brestoff, J.R.1
Kim, B.S.2
Saenz, S.A.3
Stine, R.R.4
Monticelli, L.A.5
Sonnenberg, G.F.6
Thome, J.J.7
Farber, D.L.8
Lutfy, K.9
Seale, P.10
Artis, D.11
-
7
-
-
0025293261
-
Influence of mild cold on 24 h energy expenditure in 'normally' clothed adults
-
Warwick PM, Busby R. Influence of mild cold on 24 h energy expenditure in 'normally' clothed adults. Br JNutr. 2007;63(3):481-488.
-
(2007)
Br JNutr
, vol.63
, Issue.3
, pp. 481-488
-
-
Warwick, P.M.1
Busby, R.2
-
8
-
-
0033794456
-
Physiological blocking of the mechanisms of cold death: theoretical and experimental considerations
-
Ivanov KP. Physiological blocking of the mechanisms of cold death: theoretical and experimental considerations. J Therm Biol. 2000;25(6):467-479.
-
(2000)
J Therm Biol
, vol.25
, Issue.6
, pp. 467-479
-
-
Ivanov, K.P.1
-
9
-
-
64349095231
-
Cold-activated brown adipose tissue in healthy men
-
van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM, Drossaerts JMAFL, Kemerink GJ, Bouvy ND, Schrauwen P, Teule GJJ. Cold-activated brown adipose tissue in healthy men.NEngl J Med. 2009;360(15):1500-1508.
-
(2009)
NEngl J Med
, vol.360
, Issue.15
, pp. 1500-1508
-
-
van Marken Lichtenbelt, W.D.1
Vanhommerig, J.W.2
Smulders, N.M.3
Drossaerts, J.M.A.F.L.4
Kemerink, G.J.5
Bouvy, N.D.6
Schrauwen, P.7
Teule, G.J.J.8
-
10
-
-
0006815637
-
Thermoregulatory and adaptive behavior of brown adipose tissue
-
Smith RE. Thermoregulatory and adaptive behavior of brown adipose tissue. Science. 1964;146(3652):1686-1689.
-
(1964)
Science
, vol.146
, Issue.3652
, pp. 1686-1689
-
-
Smith, R.E.1
-
11
-
-
84931039048
-
A stringent validation of mouse adipose tissue identity markers
-
de Jong JMA, Larsson O, Cannon B, Nedergaard J. A stringent validation of mouse adipose tissue identity markers. Am J Physiol Endocrinol Metab. 2015;308(12):E1085-E1105.
-
(2015)
Am J Physiol Endocrinol Metab
, vol.308
, Issue.12
, pp. E1085-E1105
-
-
de Jong, J.M.A.1
Larsson, O.2
Cannon, B.3
Nedergaard, J.4
-
12
-
-
37549014480
-
A thermosensory pathway that controls body temperature
-
Nakamura K, Morrison SF. A thermosensory pathway that controls body temperature. Nat Neurosci. 2007;11(1):62-71.
-
(2007)
Nat Neurosci
, vol.11
, Issue.1
, pp. 62-71
-
-
Nakamura, K.1
Morrison, S.F.2
-
13
-
-
46149086585
-
Central control of thermogenesis in mammals
-
Morrison SF, Nakamura K, Madden CJ. Central control of thermogenesis in mammals. Exp Physiol. 2008;93(7):773-797.
-
(2008)
Exp Physiol
, vol.93
, Issue.7
, pp. 773-797
-
-
Morrison, S.F.1
Nakamura, K.2
Madden, C.J.3
-
14
-
-
0034611678
-
Towards a molecular understanding of adaptive thermogenesis
-
Lowell BB, Spiegelman BM. Towards a molecular understanding of adaptive thermogenesis. Nature. 2000;404(6778):652-660.
-
(2000)
Nature
, vol.404
, Issue.6778
, pp. 652-660
-
-
Lowell, B.B.1
Spiegelman, B.M.2
-
15
-
-
0347989317
-
Brown adipose tissue: function and physiological significance
-
Cannon B, Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev. 2004;84(1):277-359.
-
(2004)
Physiol Rev
, vol.84
, Issue.1
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
16
-
-
84868213635
-
Brown adipose tissue and the regulation of nonshivering thermogenesis
-
van Marken Lichtenbelt W. Brown adipose tissue and the regulation of nonshivering thermogenesis. Curr Opin Clin Nutr Metab Care. 2012;15(6):547-552.
-
(2012)
Curr Opin Clin Nutr Metab Care
, vol.15
, Issue.6
, pp. 547-552
-
-
van Marken Lichtenbelt, W.1
-
17
-
-
1642293248
-
p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene
-
Cao W, Daniel KW, Robidoux J, Puigserver P, Medvedev AV, Bai X, Floering LM, Spiegelman BM, Collins S. p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. Mol Cell Biol. 2004;24(7):3057-3067.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.7
, pp. 3057-3067
-
-
Cao, W.1
Daniel, K.W.2
Robidoux, J.3
Puigserver, P.4
Medvedev, A.V.5
Bai, X.6
Floering, L.M.7
Spiegelman, B.M.8
Collins, S.9
-
18
-
-
0037326196
-
Peroxisome proliferator-activated receptor-g coactivator 1 a (PGC-1 a): transcriptional coactivator and metabolic regulator
-
Puigserver P, Spiegelman BM. Peroxisome proliferator-activated receptor-g coactivator 1 a (PGC-1 a): transcriptional coactivator and metabolic regulator. Endocr Rev. 2003;24(1):78-90.
-
(2003)
Endocr Rev
, vol.24
, Issue.1
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
19
-
-
77952958684
-
Brown adipose tissue-a new role in humans?
-
Lidell ME, Enerbäck S. Brown adipose tissue-a new role in humans? Nat Rev Endocrinol. 2010;6(6):319-325.
-
(2010)
Nat Rev Endocrinol
, vol.6
, Issue.6
, pp. 319-325
-
-
Lidell, M.E.1
Enerbäck, S.2
-
20
-
-
34248372084
-
Myogenic gene expression signature establishes that brown and white adipocytes originate fromdistinct cell lineages
-
Timmons JA, Wennmalm K, Larsson O, Walden TB, Lassmann T, Petrovic N, Hamilton DL, Gimeno RE, Wahlestedt C, Baar K, Nedergaard J, Cannon B. Myogenic gene expression signature establishes that brown and white adipocytes originate fromdistinct cell lineages. Proc Natl Acad Sci USA. 2007;104(11):4401-4406.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.11
, pp. 4401-4406
-
-
Timmons, J.A.1
Wennmalm, K.2
Larsson, O.3
Walden, T.B.4
Lassmann, T.5
Petrovic, N.6
Hamilton, D.L.7
Gimeno, R.E.8
Wahlestedt, C.9
Baar, K.10
Nedergaard, J.11
Cannon, B.12
-
21
-
-
84883354892
-
A heterogeneous lineage origin underlies the phenotypic and molecular differences of white and beige adipocytes
-
Liu W, Shan T, Yang X, Liang S, Zhang P, Liu Y, Liu X, Kuang S. A heterogeneous lineage origin underlies the phenotypic and molecular differences of white and beige adipocytes. J Cell Sci. 2013;126(16):3527-3532.
-
(2013)
J Cell Sci
, vol.126
, Issue.16
, pp. 3527-3532
-
-
Liu, W.1
Shan, T.2
Yang, X.3
Liang, S.4
Zhang, P.5
Liu, Y.6
Liu, X.7
Kuang, S.8
-
22
-
-
84869233588
-
Human BAT possesses molecular signatures that resemble beige/brite cells
-
Sharp LZ, Shinoda K, Ohno H, ScheelDW, Tomoda E, Ruiz L, Hu H, Wang L, Pavlova Z, Gilsanz V, Kajimura S. Human BAT possesses molecular signatures that resemble beige/brite cells. PLoS One. 2012;7(11):e49452.
-
(2012)
PLoS One
, vol.7
, Issue.11
-
-
Sharp, L.Z.1
Shinoda, K.2
Ohno, H.3
Scheel, D.W.4
Tomoda, E.5
Ruiz, L.6
Hu, H.7
Wang, L.8
Pavlova, Z.9
Gilsanz, V.10
Kajimura, S.11
-
23
-
-
84864287504
-
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human
-
Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang A-H, Khandekar M, Virtanen KA, Nuutila P, Schaart G, Huang K, Tu H, van Marken Lichtenbelt WD, Hoeks J, Enerbäck S, Schrauwen P, Spiegelman BM. Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell. 2012;150(2):366-376.
-
(2012)
Cell
, vol.150
, Issue.2
, pp. 366-376
-
-
Wu, J.1
Boström, P.2
Sparks, L.M.3
Ye, L.4
Choi, J.H.5
Giang, A.-H.6
Khandekar, M.7
Virtanen, K.A.8
Nuutila, P.9
Schaart, G.10
Huang, K.11
Tu, H.12
van Marken Lichtenbelt, W.D.13
Hoeks, J.14
Enerbäck, S.15
Schrauwen, P.16
Spiegelman, B.M.17
-
24
-
-
50049122271
-
PRDM16 controls a brown fat/skeletalmuscle switch
-
Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scimè A, Devarakonda S, Conroe HM, Erdjument-Bromage H, Tempst P, Rudnicki MA, Beier DR, Spiegelman BM. PRDM16 controls a brown fat/skeletalmuscle switch.Nature. 2008;454(7207):961-967.
-
(2008)
Nature
, vol.454
, Issue.7207
, pp. 961-967
-
-
Seale, P.1
Bjork, B.2
Yang, W.3
Kajimura, S.4
Chin, S.5
Kuang, S.6
Scimè, A.7
Devarakonda, S.8
Conroe, H.M.9
Erdjument-Bromage, H.10
Tempst, P.11
Rudnicki, M.A.12
Beier, D.R.13
Spiegelman, B.M.14
-
25
-
-
69349088117
-
Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-β transcriptional complex
-
Kajimura S, Seale P, Kubota K, Lunsford E, Frangioni JV, Gygi SP, Spiegelman BM. Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-β transcriptional complex. Nature. 2009; 460(7259):1154-1158.
-
(2009)
Nature
, vol.460
, Issue.7259
, pp. 1154-1158
-
-
Kajimura, S.1
Seale, P.2
Kubota, K.3
Lunsford, E.4
Frangioni, J.V.5
Gygi, S.P.6
Spiegelman, B.M.7
-
26
-
-
52649150323
-
Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARgamma agonist
-
Petrovic N, Shabalina IG, Timmons JA, Cannon B, Nedergaard J. Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARgamma agonist. Am J Physiol Endocrinol Metab. 2008;295(2):E287-E296.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
, Issue.2
, pp. E287-E296
-
-
Petrovic, N.1
Shabalina, I.G.2
Timmons, J.A.3
Cannon, B.4
Nedergaard, J.5
-
27
-
-
84865792944
-
PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors
-
Sanchez-Gurmaches J, Hung C-M, Sparks CA, Tang Y, Li H, Guertin DA. PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors. Cell Metab. 2012;16(3):348-362.
-
(2012)
Cell Metab
, vol.16
, Issue.3
, pp. 348-362
-
-
Sanchez-Gurmaches, J.1
Hung, C.-M.2
Sparks, C.A.3
Tang, Y.4
Li, H.5
Guertin, D.A.6
-
28
-
-
84903127498
-
Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed
-
Sanchez-Gurmaches J, Guertin DA. Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed. Nat Commun. 2014;5:4099.
-
(2014)
Nat Commun
, vol.5
, pp. 4099
-
-
Sanchez-Gurmaches, J.1
Guertin, D.A.2
-
29
-
-
84881259220
-
Distinct populations of adipogenic and myogenic Myf5-lineage progenitors in white adipose tissues
-
Shan T, Liang X, Bi P, Zhang P, Liu W, Kuang S. Distinct populations of adipogenic and myogenic Myf5-lineage progenitors in white adipose tissues. J Lipid Res. 2013;54(8):2214-2224.
-
(2013)
J Lipid Res
, vol.54
, Issue.8
, pp. 2214-2224
-
-
Shan, T.1
Liang, X.2
Bi, P.3
Zhang, P.4
Liu, W.5
Kuang, S.6
-
30
-
-
84907683854
-
Ebf2 is a selective marker of brown and beige adipogenic precursor cells
-
Wang W, Kissig M, Rajakumari S, Huang L, Lim HW, Won K-J, Seale P. Ebf2 is a selective marker of brown and beige adipogenic precursor cells. Proc Natl Acad Sci USA. 2014;111(40):14466-14471.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.40
, pp. 14466-14471
-
-
Wang, W.1
Kissig, M.2
Rajakumari, S.3
Huang, L.4
Lim, H.W.5
Won, K.-J.6
Seale, P.7
-
31
-
-
0027051199
-
Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization
-
Cousin B, Cinti S, Morroni M, Raimbault S, Ricquier D, Pénicaud L, Casteilla L. Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization. J Cell Sci. 1992;103(pt 4):931-942.
-
(1992)
J Cell Sci
, vol.103
, pp. 931-942
-
-
Cousin, B.1
Cinti, S.2
Morroni, M.3
Raimbault, S.4
Ricquier, D.5
Pénicaud, L.6
Casteilla, L.7
-
32
-
-
0033825933
-
Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes
-
Himms-Hagen J, Melnyk A, Zingaretti MC, Ceresi E, Barbatelli G, Cinti S. Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes. Am J Physiol Cell Physiol. 2000;279(3):C670-C681.
-
(2000)
Am J Physiol Cell Physiol
, vol.279
, Issue.3
, pp. C670-C681
-
-
Himms-Hagen, J.1
Melnyk, A.2
Zingaretti, M.C.3
Ceresi, E.4
Barbatelli, G.5
Cinti, S.6
-
33
-
-
25144489034
-
Metabolic and cellular plasticity in white adipose tissue I: effects of b3-adrenergic receptor activation
-
Granneman JG, Li P, Zhu Z, Lu Y. Metabolic and cellular plasticity in white adipose tissue I: effects of b3-adrenergic receptor activation. Am J Physiol Endocrinol Metab. 2005;289(4): E608-E616.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
, Issue.4
, pp. E608-E616
-
-
Granneman, J.G.1
Li, P.2
Zhu, Z.3
Lu, Y.4
-
34
-
-
84928114276
-
Activation and recruitment of brown adipose tissue as anti-obesity regimens in humans
-
Yoneshiro T, Saito M. Activation and recruitment of brown adipose tissue as anti-obesity regimens in humans. Ann Med. 2015;47(2):133-141.
-
(2015)
Ann Med
, vol.47
, Issue.2
, pp. 133-141
-
-
Yoneshiro, T.1
Saito, M.2
-
35
-
-
84924365670
-
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
-
Berbée JFP, Boon MR, Khedoe PPSJ, Bartelt A, Schlein C, Worthmann A, Kooijman S, Hoeke G, Mol IM, John C, Jung C, Vazirpanah N, Brouwers LPJ, Gordts PLSM, Esko JD, Hiemstra PS, Havekes LM, Scheja L, Heeren J, Rensen PCN. Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development. Nat Commun. 2015;6:6356.
-
(2015)
Nat Commun
, vol.6
, pp. 6356
-
-
Berbée, J.F.P.1
Boon, M.R.2
Khedoe, P.P.S.J.3
Bartelt, A.4
Schlein, C.5
Worthmann, A.6
Kooijman, S.7
Hoeke, G.8
Mol, I.M.9
John, C.10
Jung, C.11
Vazirpanah, N.12
Brouwers, L.P.J.13
Gordts, P.L.S.M.14
Esko, J.D.15
Hiemstra, P.S.16
Havekes, L.M.17
Scheja, L.18
Heeren, J.19
Rensen, P.C.N.20
more..
-
36
-
-
78650945931
-
Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
-
Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, Cohen P, Cinti S, Spiegelman BM. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. J Clin Invest. 2011;121(1):96-105.
-
(2011)
J Clin Invest
, vol.121
, Issue.1
, pp. 96-105
-
-
Seale, P.1
Conroe, H.M.2
Estall, J.3
Kajimura, S.4
Frontini, A.5
Ishibashi, J.6
Cohen, P.7
Cinti, S.8
Spiegelman, B.M.9
-
37
-
-
84902097377
-
Meteorinlike is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis
-
Rao RR, Long JZ, White JP, Svensson KJ, Lou J, Lokurkar I, Jedrychowski MP, Ruas JL, Wrann CD, Lo JC, Camera DM, Lachey J, Gygi S, Seehra J, Hawley JA, Spiegelman BM.Meteorinlike is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis. Cell. 2014;157(6):1279-1291.
-
(2014)
Cell
, vol.157
, Issue.6
, pp. 1279-1291
-
-
Rao, R.R.1
Long, J.Z.2
White, J.P.3
Svensson, K.J.4
Lou, J.5
Lokurkar, I.6
Jedrychowski, M.P.7
Ruas, J.L.8
Wrann, C.D.9
Lo, J.C.10
Camera, D.M.11
Lachey, J.12
Gygi, S.13
Seehra, J.14
Hawley, J.A.15
Spiegelman, B.M.16
-
38
-
-
84907485620
-
Browning of white adipose cells by intermediate metabolites: an adaptive mechanism to alleviate redox pressure
-
Carrière A, Jeanson Y, Berger-Müller S, André M, Chenouard V, Arnaud E, Barreau C, Walther R, Galinier A, Wdziekonski B, Villageois P, Louche K, Collas P, Moro C, Dani C, Villarroya F, Casteilla L. Browning of white adipose cells by intermediate metabolites: an adaptive mechanism to alleviate redox pressure. Diabetes. 2014;63(10):3253-3265.
-
(2014)
Diabetes
, vol.63
, Issue.10
, pp. 3253-3265
-
-
Carrière, A.1
Jeanson, Y.2
Berger-Müller, S.3
André, M.4
Chenouard, V.5
Arnaud, E.6
Barreau, C.7
Walther, R.8
Galinier, A.9
Wdziekonski, B.10
Villageois, P.11
Louche, K.12
Collas, P.13
Moro, C.14
Dani, C.15
Villarroya, F.16
Casteilla, L.17
-
39
-
-
84862776702
-
A PGC1-a-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Højlund K, Gygi SP, Spiegelman BMA. A PGC1-a-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012;481(7382):463-468.
-
(2012)
Nature
, vol.481
, Issue.7382
, pp. 463-468
-
-
Boström, P.1
Wu, J.2
Jedrychowski, M.P.3
Korde, A.4
Ye, L.5
Lo, J.C.6
Rasbach, K.A.7
Boström, E.A.8
Choi, J.H.9
Long, J.Z.10
Kajimura, S.11
Zingaretti, M.C.12
Vind, B.F.13
Tu, H.14
Cinti, S.15
Højlund, K.16
Gygi, S.P.17
Spiegelman, B.M.A.18
-
40
-
-
84863012022
-
FGF21 regulates PGC-1a and browning of white adipose tissues in adaptive thermogenesis
-
Fisher FM, Kleiner S, Douris N, Fox EC, Mepani RJ, Verdeguer F, Wu J, Kharitonenkov A, Flier JS, Maratos-Flier E, Spiegelman BM. FGF21 regulates PGC-1a and browning of white adipose tissues in adaptive thermogenesis. Genes Dev. 2012;26(3):271-281.
-
(2012)
Genes Dev
, vol.26
, Issue.3
, pp. 271-281
-
-
Fisher, F.M.1
Kleiner, S.2
Douris, N.3
Fox, E.C.4
Mepani, R.J.5
Verdeguer, F.6
Wu, J.7
Kharitonenkov, A.8
Flier, J.S.9
Maratos-Flier, E.10
Spiegelman, B.M.11
-
41
-
-
84874450879
-
BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis
-
Qian S-W, Tang Y, Li X, Liu Y, Zhang Y-Y, Huang H-Y, Xue R-D, Yu H-Y, Guo L, Gao H-D, Liu Y, Sun X, Li Y-M, Jia W-P, Tang Q-Q. BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis. Proc Natl Acad Sci USA. 2013;110(9):E798-E807.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.9
, pp. E798-E807
-
-
Qian, S.-W.1
Tang, Y.2
Li, X.3
Liu, Y.4
Zhang, Y.-Y.5
Huang, H.-Y.6
Xue, R.-D.7
Yu, H.-Y.8
Guo, L.9
Gao, H.-D.10
Liu, Y.11
Sun, X.12
Li, Y.-M.13
Jia, W.-P.14
Tang, Q.-Q.15
-
42
-
-
84884183691
-
BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality
-
Boon MR, van den Berg SAA, Wang Y, van den Bossche J, Karkampouna S, Bauwens M, De Saint-HubertM, van der Horst G, Vukicevic S, de Winther MPJ, Havekes LM, Jukema JW, Tamsma JT, van der Pluijm G, van Dijk KW, Rensen PCN. BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality. PLoS One. 2013;8(9):e74083.
-
(2013)
PLoS One
, vol.8
, Issue.9
-
-
Boon, M.R.1
van den Berg, S.A.A.2
Wang, Y.3
van den Bossche, J.4
Karkampouna, S.5
Bauwens, M.6
De Saint-Hubert, M.7
van der Horst, G.8
Vukicevic, S.9
de Winther, M.P.J.10
Havekes, L.M.11
Jukema, J.W.12
Tamsma, J.T.13
van der Pluijm, G.14
van Dijk, K.W.15
Rensen, P.C.N.16
-
43
-
-
77952623888
-
The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation
-
Barbatelli G, Murano I, Madsen L, Hao Q, Jimenez M, Kristiansen K, Giacobino JP, De Matteis R, Cinti S. The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation. Am J Physiol Endocrinol Metab. 2010;298(6): E1244-E1253.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
, Issue.6
, pp. E1244-E1253
-
-
Barbatelli, G.1
Murano, I.2
Madsen, L.3
Hao, Q.4
Jimenez, M.5
Kristiansen, K.6
Giacobino, J.P.7
De Matteis, R.8
Cinti, S.9
-
44
-
-
0036862318
-
Adipocyte differentiation and transdifferentiation: plasticity of the adipose organ
-
Cinti S. Adipocyte differentiation and transdifferentiation: plasticity of the adipose organ. J Endocrinol Invest. 2014;25(10): 823-835.
-
(2014)
J Endocrinol Invest
, vol.25
, Issue.10
, pp. 823-835
-
-
Cinti, S.1
-
45
-
-
84859465056
-
In vivo identification of bipotential adipocyte progenitors recruited by b3-adrenoceptor activation and high-fat feeding
-
Lee Y-H, Petkova AP, Mottillo EP, Granneman JG. In vivo identification of bipotential adipocyte progenitors recruited by b3-adrenoceptor activation and high-fat feeding. Cell Metab. 2012; 15(4):480-491.
-
(2012)
Cell Metab
, vol.15
, Issue.4
, pp. 480-491
-
-
Lee, Y.-H.1
Petkova, A.P.2
Mottillo, E.P.3
Granneman, J.G.4
-
46
-
-
84925787770
-
Cellular origins of cold-induced brown adipocytes in adult mice
-
Lee Y-H, Petkova AP, Konkar AA, Granneman JG. Cellular origins of cold-induced brown adipocytes in adult mice. FASEB J. 2014;29(1):286-299.
-
(2014)
FASEB J
, vol.29
, Issue.1
, pp. 286-299
-
-
Lee, Y.-H.1
Petkova, A.P.2
Konkar, A.A.3
Granneman, J.G.4
-
47
-
-
84878525220
-
Bi-directional interconversion of brite and white adipocytes
-
RosenwaldM, Perdikari A, Rülicke T, Wolfrum C. Bi-directional interconversion of brite and white adipocytes. Nat Cell Biol. 2013; 15(6):659-667.
-
(2013)
Nat Cell Biol
, vol.15
, Issue.6
, pp. 659-667
-
-
Rosenwald, M.1
Perdikari, A.2
Rülicke, T.3
Wolfrum, C.4
-
48
-
-
84887502374
-
Tracking adipogenesis during white adipose tissue development, expansion and regeneration
-
Wang QA, Tao C, Gupta RK, Scherer PE. Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nat Med. 2013;19(10):1338-1344.
-
(2013)
Nat Med
, vol.19
, Issue.10
, pp. 1338-1344
-
-
Wang, Q.A.1
Tao, C.2
Gupta, R.K.3
Scherer, P.E.4
-
49
-
-
84945456543
-
Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase
-
Ye R, Wang QA, Tao C, Vishvanath L, Shao M, McDonald JG, Gupta RK, Scherer PE. Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase. Mol Metab. 2015;4(11):771-778.
-
(2015)
Mol Metab
, vol.4
, Issue.11
, pp. 771-778
-
-
Ye, R.1
Wang, Q.A.2
Tao, C.3
Vishvanath, L.4
Shao, M.5
McDonald, J.G.6
Gupta, R.K.7
Scherer, P.E.8
-
50
-
-
84899755491
-
Vascular rarefaction mediates whitening of brown fat in obesity
-
Shimizu I, Aprahamian T, Kikuchi R, Shimizu A, Papanicolaou KN, MacLauchlan S, Maruyama S, Walsh K. Vascular rarefaction mediates whitening of brown fat in obesity. J Clin Invest. 2014; 124(5):2099-2112.
-
(2014)
J Clin Invest
, vol.124
, Issue.5
, pp. 2099-2112
-
-
Shimizu, I.1
Aprahamian, T.2
Kikuchi, R.3
Shimizu, A.4
Papanicolaou, K.N.5
MacLauchlan, S.6
Maruyama, S.7
Walsh, K.8
-
51
-
-
84930443140
-
Adipose VEGF links the white-to-brown fat switch with environmental, genetic, and pharmacological stimuli in male mice
-
During MJ, Liu X, Huang W, Magee D, Slater A, McMurphy T, Wang C, Cao L. Adipose VEGF links the white-to-brown fat switch with environmental, genetic, and pharmacological stimuli in male mice. Endocrinology. 2015;156(6):2059-2073.
-
(2015)
Endocrinology
, vol.156
, Issue.6
, pp. 2059-2073
-
-
During, M.J.1
Liu, X.2
Huang, W.3
Magee, D.4
Slater, A.5
McMurphy, T.6
Wang, C.7
Cao, L.8
-
52
-
-
84904433925
-
Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease
-
Hung C-M, Calejman CM, Sanchez-Gurmaches J, Li H, Clish CB, Hettmer S, Wagers AJ, Guertin DA. Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease. Cell Reports. 2014;8(1): 256-271.
-
(2014)
Cell Reports
, vol.8
, Issue.1
, pp. 256-271
-
-
Hung, C.-M.1
Calejman, C.M.2
Sanchez-Gurmaches, J.3
Li, H.4
Clish, C.B.5
Hettmer, S.6
Wagers, A.J.7
Guertin, D.A.8
-
53
-
-
84930216250
-
Prolonged daily light exposure increases body fat mass through attenuation of brown adipose tissue activity
-
Kooijman S, van den Berg R, Ramkisoensing A, Boon MR, Kuipers EN, Loef M, Zonneveld TCM, Lucassen EA, Sips HCM, Chatzispyrou IA, Houtkooper RH, Meijer JH, Coomans CP, Biermasz NR, Rensen PCN. Prolonged daily light exposure increases body fat mass through attenuation of brown adipose tissue activity. Proc Natl Acad Sci USA. 2015;112(21):6748-6753.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, Issue.21
, pp. 6748-6753
-
-
Kooijman, S.1
van den Berg, R.2
Ramkisoensing, A.3
Boon, M.R.4
Kuipers, E.N.5
Loef, M.6
Zonneveld, T.C.M.7
Lucassen, E.A.8
Sips, H.C.M.9
Chatzispyrou, I.A.10
Houtkooper, R.H.11
Meijer, J.H.12
Coomans, C.P.13
Biermasz, N.R.14
Rensen, P.C.N.15
-
54
-
-
1842409029
-
Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese
-
Enerbäck S, Jacobsson A, Simpson EM, Guerra C, Yamashita H, Harper M-E, Kozak LP. Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese. Nature. 1997;387(6628): 90-94.
-
(1997)
Nature
, vol.387
, Issue.6628
, pp. 90-94
-
-
Enerbäck, S.1
Jacobsson, A.2
Simpson, E.M.3
Guerra, C.4
Yamashita, H.5
Harper, M.-E.6
Kozak, L.P.7
-
55
-
-
23844474515
-
UCP1 deficiency increases susceptibility to diet-induced obesity with age
-
Kontani Y, Wang Y, Kimura K, Inokuma KI, Saito M, Suzuki-Miura T, Wang Z, Sato Y, Mori N, Yamashita H. UCP1 deficiency increases susceptibility to diet-induced obesity with age. Aging Cell. 2005;4(3):147-155.
-
(2005)
Aging Cell
, vol.4
, Issue.3
, pp. 147-155
-
-
Kontani, Y.1
Wang, Y.2
Kimura, K.3
Inokuma, K.I.4
Saito, M.5
Suzuki-Miura, T.6
Wang, Z.7
Sato, Y.8
Mori, N.9
Yamashita, H.10
-
56
-
-
58749091645
-
UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
-
Feldmann HM, Golozoubova V, Cannon B, Nedergaard J. UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab. 2009;9(2):203-209.
-
(2009)
Cell Metab
, vol.9
, Issue.2
, pp. 203-209
-
-
Feldmann, H.M.1
Golozoubova, V.2
Cannon, B.3
Nedergaard, J.4
-
57
-
-
0027731309
-
Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
-
Lowell BB, S-Susulic V, Hamann A, Lawitts JA, Himms-Hagen J, Boyer BB, Kozak LP, Flier JS. Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature. 1993; 366(6457):740-742.
-
(1993)
Nature
, vol.366
, Issue.6457
, pp. 740-742
-
-
Lowell, B.B.1
S-Susulic, V.2
Hamann, A.3
Lawitts, J.A.4
Himms-Hagen, J.5
Boyer, B.B.6
Kozak, L.P.7
Flier, J.S.8
-
58
-
-
0037008157
-
betaAR signaling required for diet-induced thermogenesis and obesity resistance
-
Bachman ES, Dhillon H, Zhang C-Y, Cinti S, Bianco AC, Kobilka BK, Lowell BB. betaAR signaling required for diet-induced thermogenesis and obesity resistance. Science. 2002;297(5582): 843-845.
-
(2002)
Science
, vol.297
, Issue.5582
, pp. 843-845
-
-
Bachman, E.S.1
Dhillon, H.2
Zhang, C.-Y.3
Cinti, S.4
Bianco, A.C.5
Kobilka, B.K.6
Lowell, B.B.7
-
59
-
-
0030991928
-
Thermoregulatory and metabolic phenotypes of mice lacking noradrenaline and adrenaline
-
Thomas SA, Palmiter RD. Thermoregulatory and metabolic phenotypes of mice lacking noradrenaline and adrenaline. Nature. 1997;387(6628):94-97.
-
(1997)
Nature
, vol.387
, Issue.6628
, pp. 94-97
-
-
Thomas, S.A.1
Palmiter, R.D.2
-
60
-
-
33645841079
-
Leptin is required for uncoupling protein-1-independent thermogenesis during cold stress
-
Ukropec J, Anunciado RV, Ravussin Y, Kozak LP. Leptin is required for uncoupling protein-1-independent thermogenesis during cold stress. Endocrinology. 2006;147(5):2468-2480.
-
(2006)
Endocrinology
, vol.147
, Issue.5
, pp. 2468-2480
-
-
Ukropec, J.1
Anunciado, R.V.2
Ravussin, Y.3
Kozak, L.P.4
-
61
-
-
84897138397
-
Fatty acid binding protein 4 and 5 play a crucial role in thermogenesis under the conditions of fasting and cold stress
-
Syamsunarno MRAA, Iso T, Yamaguchi A, Hanaoka H, Putri M, Obokata M, Sunaga H, Koitabashi N, Matsui H, Maeda K, Endo K, Tsushima Y, Yokoyama T, Kurabayashi M. Fatty acid binding protein 4 and 5 play a crucial role in thermogenesis under the conditions of fasting and cold stress. PLoS One. 2014;9(3):e90825.
-
(2014)
PLoS One
, vol.9
, Issue.3
-
-
Syamsunarno, M.R.A.A.1
Iso, T.2
Yamaguchi, A.3
Hanaoka, H.4
Putri, M.5
Obokata, M.6
Sunaga, H.7
Koitabashi, N.8
Matsui, H.9
Maeda, K.10
Endo, K.11
Tsushima, Y.12
Yokoyama, T.13
Kurabayashi, M.14
-
62
-
-
84873842067
-
p62 links b-adrenergic input to mitochondrial function and thermogenesis
-
Müller TD, Lee SJ, Jastroch M, Kabra D, Stemmer K, Aichler M, Abplanalp B, Ananthakrishnan G, Bhardwaj N, Collins S, Divanovic S, Endele M, Finan B, Gao Y, Habegger KM, Hembree J, Heppner KM, Hofmann S, Holland J, Küchler D, Kutschke M, Krishna R, Lehti M, Oelkrug R, Ottaway N, Perez-Tilve D, Raver C, Walch AK, Schriever SC, Speakman J, Tseng Y-H, Diaz-Meco M, Pfluger PT, Moscat J, Tschö p MH. p62 links b-adrenergic input to mitochondrial function and thermogenesis. J Clin Invest. 2012;123(1):469-478.
-
(2012)
J Clin Invest
, vol.123
, Issue.1
, pp. 469-478
-
-
Müller, T.D.1
Lee, S.J.2
Jastroch, M.3
Kabra, D.4
Stemmer, K.5
Aichler, M.6
Abplanalp, B.7
Ananthakrishnan, G.8
Bhardwaj, N.9
Collins, S.10
Divanovic, S.11
Endele, M.12
Finan, B.13
Gao, Y.14
Habegger, K.M.15
Hembree, J.16
Heppner, K.M.17
Hofmann, S.18
Holland, J.19
Küchler, D.20
Kutschke, M.21
Krishna, R.22
Lehti, M.23
Oelkrug, R.24
Ottaway, N.25
Perez-Tilve, D.26
Raver, C.27
Walch, A.K.28
Schriever, S.C.29
Speakman, J.30
Tseng, Y.-H.31
Diaz-Meco, M.32
Pfluger, P.T.33
Moscat, J.34
Tschöp, M.H.35
more..
-
63
-
-
84898470352
-
Effect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in mice
-
Ravussin Y, Xiao C, Gavrilova O, Reitman ML. Effect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in mice. PLoS One. 2014;9(1):e85876.
-
(2014)
PLoS One
, vol.9
, Issue.1
-
-
Ravussin, Y.1
Xiao, C.2
Gavrilova, O.3
Reitman, M.L.4
-
64
-
-
79751503329
-
Brown adipose tissue activity controls triglyceride clearance
-
Bartelt A, Bruns OT, Reimer R, Hohenberg H, Ittrich H, Peldschus K, KaulMG, TromsdorfUI, WellerH, WaurischC, Eychmüller A, Gordts PLSM, Rinninger F, Bruegelmann K, Freund B, Nielsen P, Merkel M, Heeren J. Brown adipose tissue activity controls triglyceride clearance. Nat Med. 2011;17(2):200-205.
-
(2011)
Nat Med
, vol.17
, Issue.2
, pp. 200-205
-
-
Bartelt, A.1
Bruns, O.T.2
Reimer, R.3
Hohenberg, H.4
Ittrich, H.5
Peldschus, K.6
Kaul, M.G.7
Tromsdorf, U.I.8
Weller, H.9
Waurisch, C.10
Eychmüller, A.11
Gordts, P.L.S.M.12
Rinninger, F.13
Bruegelmann, K.14
Freund, B.15
Nielsen, P.16
Merkel, M.17
Heeren, J.18
-
65
-
-
84879846992
-
Cold exposure promotes atherosclerotic plaque growth and instability via UCP1-dependent lipolysis
-
Dong M, Yang X, Lim S, Cao Z, Honek J, Lu H, Zhang C, Seki T, Hosaka K, Wahlberg E, Yang J, Zhang L, Länne T, Sun B, Li X, Liu Y, Zhang Y, Cao Y. Cold exposure promotes atherosclerotic plaque growth and instability via UCP1-dependent lipolysis. Cell Metab. 2013;18(1):118-129.
-
(2013)
Cell Metab
, vol.18
, Issue.1
, pp. 118-129
-
-
Dong, M.1
Yang, X.2
Lim, S.3
Cao, Z.4
Honek, J.5
Lu, H.6
Zhang, C.7
Seki, T.8
Hosaka, K.9
Wahlberg, E.10
Yang, J.11
Zhang, L.12
Länne, T.13
Sun, B.14
Li, X.15
Liu, Y.16
Zhang, Y.17
Cao, Y.18
-
66
-
-
0028224485
-
Effect of CL-316, 243, a thermogenic beta 3-agonist, on energy balance and brown and white adipose tissues in rats
-
Himms-Hagen J, Cui J, Danforth E, Jr, Taatjes DJ, Lang SS, Waters BL, Claus TH. Effect of CL-316, 243, a thermogenic beta 3-agonist, on energy balance and brown and white adipose tissues in rats. Am J Physiol. 1994;266(4, pt 2):R1371-R1382.
-
(1994)
Am J Physiol
, vol.266
, Issue.4
, pp. R1371-R1382
-
-
Himms-Hagen, J.1
Cui, J.2
Danforth, E.3
Taatjes, D.J.4
Lang, S.S.5
Waters, B.L.6
Claus, T.H.7
-
67
-
-
0028865142
-
Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity
-
Kopecky J, Clarke G, Enerbäck S, Spiegelman B, Kozak LP. Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity. J Clin Invest. 1995; 96(6):2914-2923.
-
(1995)
J Clin Invest
, vol.96
, Issue.6
, pp. 2914-2923
-
-
Kopecky, J.1
Clarke, G.2
Enerbäck, S.3
Spiegelman, B.4
Kozak, L.P.5
-
68
-
-
17944377509
-
FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance
-
Cederberg A, Grønning LM, Ahrén B, Taskén K, Carlsson P, Enerbäck S. FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance. Cell. 2001;106(5):563-573.
-
(2001)
Cell
, vol.106
, Issue.5
, pp. 563-573
-
-
Cederberg, A.1
Grønning, L.M.2
Ahrén, B.3
Taskén, K.4
Carlsson, P.5
Enerbäck, S.6
-
69
-
-
20044386339
-
Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance
-
Kim JK, Kim H-J, Park S-Y, Cederberg A, Westergren R, Nilsson D, Higashimori T, Cho Y-R, Liu Z-X, Dong J, Cline GW, Enerback S, Shulman GI. Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance. Diabetes. 2005;54(6):1657-1663.
-
(2005)
Diabetes
, vol.54
, Issue.6
, pp. 1657-1663
-
-
Kim, J.K.1
Kim, H.-J.2
Park, S.-Y.3
Cederberg, A.4
Westergren, R.5
Nilsson, D.6
Higashimori, T.7
Cho, Y.-R.8
Liu, Z.-X.9
Dong, J.10
Cline, G.W.11
Enerback, S.12
Shulman, G.I.13
-
70
-
-
0041353552
-
Cidea-deficient mice have lean phenotype and are resistant to obesity
-
Zhou Z, Yon Toh S, Chen Z, Guo K, Ng CP, Ponniah S, Lin S-C, Hong W, Li P. Cidea-deficient mice have lean phenotype and are resistant to obesity. Nat Genet. 2003;35(1):49-56.
-
(2003)
Nat Genet
, vol.35
, Issue.1
, pp. 49-56
-
-
Zhou, Z.1
Yon Toh, S.2
Chen, Z.3
Guo, K.4
Ng, C.P.5
Ponniah, S.6
Lin, S.-C.7
Hong, W.8
Li, P.9
-
71
-
-
84857408775
-
Reversal of type 1 diabetes in mice by brown adipose tissue transplant
-
Gunawardana SC, Piston DW. Reversal of type 1 diabetes in mice by brown adipose tissue transplant. Diabetes. 2012;61(3): 674-682.
-
(2012)
Diabetes
, vol.61
, Issue.3
, pp. 674-682
-
-
Gunawardana, S.C.1
Piston, D.W.2
-
72
-
-
84873854027
-
Brown adipose tissue regulates glucose homeostasis and insulin sensitivity
-
Stanford KI, Middelbeek RJW, Townsend KL, An D, Nygaard EB, HitchcoxKM, MarkanKR, NakanoK, HirshmanMF, Tseng Y-H, Goodyear LJ. Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. J Clin Invest. 2012;123(1): 215-223.
-
(2012)
J Clin Invest
, vol.123
, Issue.1
, pp. 215-223
-
-
Stanford, K.I.1
Middelbeek, R.J.W.2
Townsend, K.L.3
An, D.4
Nygaard, E.B.5
Hitchcox, K.M.6
Markan, K.R.7
Nakano, K.8
Hirshman, M.F.9
Tseng, Y.-H.10
Goodyear, L.J.11
-
73
-
-
84889674445
-
Enhanced sympathetic activity in mice with brown adipose tissue transplantation (transBATation)
-
Zhu Z, Spicer EG, Gavini CK, Goudjo-Ako AJ, Novak CM, Shi H. Enhanced sympathetic activity in mice with brown adipose tissue transplantation (transBATation). Physiol Behav. 2014;125: 21-29.
-
(2014)
Physiol Behav
, vol.125
, pp. 21-29
-
-
Zhu, Z.1
Spicer, E.G.2
Gavini, C.K.3
Goudjo-Ako, A.J.4
Novak, C.M.5
Shi, H.6
-
74
-
-
84977139404
-
Pharmacological and genetic manipulation of p53 in brown fat at adult but not embryonic stages regulates thermogenesis and body weight in male mice
-
Al-Massadi O, Porteiro B, Kuhlow D, Köhler M, Gonzalez-Rellan MJ, Garcia-Lavandeira M, Díaz-Rodríguez E, Quiñones M, Senra A, Alvarez CV, Ló pez M, Diéguez C, Schulz TJ, Nogueiras R. Pharmacological and genetic manipulation of p53 in brown fat at adult but not embryonic stages regulates thermogenesis and body weight in male mice. Endocrinology. 2016;157(7):2735-2749.
-
(2016)
Endocrinology
, vol.157
, Issue.7
, pp. 2735-2749
-
-
Al-Massadi, O.1
Porteiro, B.2
Kuhlow, D.3
Köhler, M.4
Gonzalez-Rellan, M.J.5
Garcia-Lavandeira, M.6
Díaz-Rodríguez, E.7
Quiñones, M.8
Senra, A.9
Alvarez, C.V.10
López, M.11
Diéguez, C.12
Schulz, T.J.13
Nogueiras, R.14
-
75
-
-
84970938019
-
USF1 deficiency activates brown adipose tissue and improves cardiometabolic health
-
Laurila P-P, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SAA, Autio A, Sarin A-P, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttil ä J, Mäkel ä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppäl ä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen M-R, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PCN, Suomalainen A, Jauhiainen M. USF1 deficiency activates brown adipose tissue and improves cardiometabolic health. Sci Transl Med. 2016;8:323ra313.
-
(2016)
Sci Transl Med
, vol.8
-
-
Laurila, P.-P.1
Soronen, J.2
Kooijman, S.3
Forsström, S.4
Boon, M.R.5
Surakka, I.6
Kaiharju, E.7
Coomans, C.P.8
Van Den Berg, S.A.A.9
Autio, A.10
Sarin, A.-P.11
Kettunen, J.12
Tikkanen, E.13
Manninen, T.14
Metso, J.15
Silvennoinen, R.16
Merikanto, K.17
Ruuth, M.18
Perttilä, J.19
Mäkelä, A.20
Isomi, A.21
Tuomainen, A.M.22
Tikka, A.23
Ramadan, U.A.24
Seppälä, I.25
Lehtimäki, T.26
Eriksson, J.27
Havulinna, A.28
Jula, A.29
Karhunen, P.J.30
Salomaa, V.31
Perola, M.32
Ehnholm, C.33
Lee-Rueckert, M.34
Van Eck, M.35
Roivainen, A.36
Taskinen, M.-R.37
Peltonen, L.38
Mervaala, E.39
Jalanko, A.40
Hohtola, E.41
Olkkonen, V.M.42
Ripatti, S.43
Kovanen, P.T.44
Rensen, P.C.N.45
Suomalainen, A.46
Jauhiainen, M.47
more..
-
76
-
-
84940449753
-
Diet-induced obesity causes insulin resistance in mouse brown adipose tissue
-
Roberts-Toler C, O'Neill BT, Cypess AM. Diet-induced obesity causes insulin resistance in mouse brown adipose tissue. Obesity (Silver Spring). 2015;23(9):1765-1770.
-
(2015)
Obesity (Silver Spring)
, vol.23
, Issue.9
, pp. 1765-1770
-
-
Roberts-Toler, C.1
O'Neill, B.T.2
Cypess, A.M.3
-
77
-
-
84913602920
-
A switch from white to brown fat increases energy expenditure in cancer-associated cachexia
-
Petruzzelli M, SchweigerM, Schreiber R, Campos-Olivas R, Tsoli M, Allen J, Swarbrick M, Rose-John S, Rincon M, Robertson G, Zechner R, Wagner EF. A switch from white to brown fat increases energy expenditure in cancer-associated cachexia. Cell Metab. 2014;20(3):433-447.
-
(2014)
Cell Metab
, vol.20
, Issue.3
, pp. 433-447
-
-
Petruzzelli, M.1
Schweiger, M.2
Schreiber, R.3
Campos-Olivas, R.4
Tsoli, M.5
Allen, J.6
Swarbrick, M.7
Rose-John, S.8
Rincon, M.9
Robertson, G.10
Zechner, R.11
Wagner, E.F.12
-
78
-
-
84923797462
-
Brown adipose tissue harbors a distinct sub-population of regulatory T cells
-
Medrikova D, Sijmonsma TP, Sowodniok K, Richards DM, Delacher M, Sticht C, Gretz N, Schafmeier T, Feuerer M, Herzig S. Brown adipose tissue harbors a distinct sub-population of regulatory T cells. PLoS One. 2015;10(2):e0118534.
-
(2015)
PLoS One
, vol.10
, Issue.2
-
-
Medrikova, D.1
Sijmonsma, T.P.2
Sowodniok, K.3
Richards, D.M.4
Delacher, M.5
Sticht, C.6
Gretz, N.7
Schafmeier, T.8
Feuerer, M.9
Herzig, S.10
-
79
-
-
84938747174
-
Adiponectin enhances cold-induced browning of subcutaneous adipose tissue via promoting M2 macrophage proliferation
-
Hui X, Gu P, Zhang J, Nie T, Pan Y, Wu D, Feng T, Zhong C, Wang Y, Lam KS, Xu A. Adiponectin enhances cold-induced browning of subcutaneous adipose tissue via promoting M2 macrophage proliferation. Cell Metab. 2015;22(2):279-290.
-
(2015)
Cell Metab
, vol.22
, Issue.2
, pp. 279-290
-
-
Hui, X.1
Gu, P.2
Zhang, J.3
Nie, T.4
Pan, Y.5
Wu, D.6
Feng, T.7
Zhong, C.8
Wang, Y.9
Lam, K.S.10
Xu, A.11
-
80
-
-
84949551974
-
Microbiota depletion promotes browning of white adipose tissue and reduces obesity
-
Suárez-Zamorano N, Fabbiano S, Chevalier C, Stojanović O, Colin DJ, Stevanović A, Veyrat-Durebex C, Tarallo V, Rigo D, Germain S, Ilievska M, Montet X, Seimbille Y, Hapfelmeier S, TrajkovskiM. Microbiota depletion promotes browning of white adipose tissue and reduces obesity. Nat Med. 2015;21(12): 1497-1501.
-
(2015)
Nat Med
, vol.21
, Issue.12
, pp. 1497-1501
-
-
Suárez-Zamorano, N.1
Fabbiano, S.2
Chevalier, C.3
Stojanović, O.4
Colin, D.J.5
Stevanović, A.6
Veyrat-Durebex, C.7
Tarallo, V.8
Rigo, D.9
Germain, S.10
Ilievska, M.11
Montet, X.12
Seimbille, Y.13
Hapfelmeier, S.14
Trajkovski, M.15
-
81
-
-
84949489607
-
Gut microbiota orchestrates energy homeostasis during cold
-
Chevalier C, Stojanović O, Colin DJ, Suarez-Zamorano N, Tarallo V, Veyrat-Durebex C, Rigo D, Fabbiano S, Stevanović A, Hagemann S, Montet X, Seimbille Y, Zamboni N, Hapfelmeier S, Trajkovski M. Gut microbiota orchestrates energy homeostasis during cold. Cell. 2015;163(6):1360-1374.
-
(2015)
Cell
, vol.163
, Issue.6
, pp. 1360-1374
-
-
Chevalier, C.1
Stojanović, O.2
Colin, D.J.3
Suarez-Zamorano, N.4
Tarallo, V.5
Veyrat-Durebex, C.6
Rigo, D.7
Fabbiano, S.8
Stevanović, A.9
Hagemann, S.10
Montet, X.11
Seimbille, Y.12
Zamboni, N.13
Hapfelmeier, S.14
Trajkovski, M.15
-
82
-
-
84983756971
-
Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 expression in mice
-
Sakamoto T, Nitta T, Maruno K, Yeh YS, Kuwata H, Tomita K, Goto T, Takahashi N, Kawada T. Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 expression in mice. Am J Physiol Endocrinol Metab. 2016;310:2015.
-
(2016)
Am J Physiol Endocrinol Metab
, vol.310
, pp. 2015
-
-
Sakamoto, T.1
Nitta, T.2
Maruno, K.3
Yeh, Y.S.4
Kuwata, H.5
Tomita, K.6
Goto, T.7
Takahashi, N.8
Kawada, T.9
-
83
-
-
84897042421
-
Role of IL-6 in exercise training-and cold-induced UCP1 expression in subcutaneous white adipose tissue
-
Knudsen JG, Murholm M, Carey AL, Biensø RS, Basse AL, Allen TL, Hidalgo J, Kingwell BA, Febbraio MA, Hansen JB, Pilegaard H. Role of IL-6 in exercise training-and cold-induced UCP1 expression in subcutaneous white adipose tissue. PLoS One. 2014; 9(1):e84910.
-
(2014)
PLoS One
, vol.9
, Issue.1
-
-
Knudsen, J.G.1
Murholm, M.2
Carey, A.L.3
Biensø, R.S.4
Basse, A.L.5
Allen, T.L.6
Hidalgo, J.7
Kingwell, B.A.8
Febbraio, M.A.9
Hansen, J.B.10
Pilegaard, H.11
-
84
-
-
84907702213
-
Deficiency in adipocyte chemokine receptor CXCR4 exacerbates obesity and compromises thermoregulatory responses of brown adipose tissue in a mouse model of diet-induced obesity
-
Yao L, Heuser-Baker J, Herlea-Pana O, Zhang N, Szweda LI, Griffin TM, Barlic-Dicen J. Deficiency in adipocyte chemokine receptor CXCR4 exacerbates obesity and compromises thermoregulatory responses of brown adipose tissue in a mouse model of diet-induced obesity. FASEB J. 2014;28(10):4534-4550.
-
(2014)
FASEB J
, vol.28
, Issue.10
, pp. 4534-4550
-
-
Yao, L.1
Heuser-Baker, J.2
Herlea-Pana, O.3
Zhang, N.4
Szweda, L.I.5
Griffin, T.M.6
Barlic-Dicen, J.7
-
85
-
-
61349178824
-
The b3-adrenoceptor as a therapeutic target: current perspectives
-
Ursino MG, Vasina V, Raschi E, Crema F, De Ponti F. The b3-adrenoceptor as a therapeutic target: current perspectives. Pharmacol Res. 2009;59(4):221-234.
-
(2009)
Pharmacol Res
, vol.59
, Issue.4
, pp. 221-234
-
-
Ursino, M.G.1
Vasina, V.2
Raschi, E.3
Crema, F.4
De Ponti, F.5
-
86
-
-
84932626659
-
In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis
-
Labbé SM, Caron A, Bakan I, Laplante M, Carpentier AC, Lecomte R, Richard D. In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis. FASEB J. 2015;29(5):2046-2058.
-
(2015)
FASEB J
, vol.29
, Issue.5
, pp. 2046-2058
-
-
Labbé, S.M.1
Caron, A.2
Bakan, I.3
Laplante, M.4
Carpentier, A.C.5
Lecomte, R.6
Richard, D.7
-
87
-
-
0026647148
-
Cold exposure increases glucose utilization and glucose transporter expression in brown adipose tissue
-
Nikami H, Shimizu Y, Endoh D, Yano H, Saito M. Cold exposure increases glucose utilization and glucose transporter expression in brown adipose tissue. Biochem Biophys Res Commun. 1992; 185(3):1078-1082.
-
(1992)
Biochem Biophys Res Commun
, vol.185
, Issue.3
, pp. 1078-1082
-
-
Nikami, H.1
Shimizu, Y.2
Endoh, D.3
Yano, H.4
Saito, M.5
-
88
-
-
84950323666
-
ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure
-
Dijk W, Heine M, Vergnes L, Boon MR, Schaart G, Hesselink MKC, Reue K, van Marken Lichtenbelt WD, Olivecrona G, Rensen PCN, Heeren J, Kersten S. ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure. eLife. 2015;4:e08428.
-
(2015)
eLife
, vol.4
-
-
Dijk, W.1
Heine, M.2
Vergnes, L.3
Boon, M.R.4
Schaart, G.5
Hesselink, M.K.C.6
Reue, K.7
van Marken Lichtenbelt, W.D.8
Olivecrona, G.9
Rensen, P.C.N.10
Heeren, J.11
Kersten, S.12
-
89
-
-
84954564100
-
Role of brown fat in lipoprotein metabolism and atherosclerosis
-
Hoeke G, Kooijman S, Boon MR, Rensen PCN, Berbée JFP. Role of brown fat in lipoprotein metabolism and atherosclerosis. Circ Res. 2016;118(1):173-182.
-
(2016)
Circ Res
, vol.118
, Issue.1
, pp. 173-182
-
-
Hoeke, G.1
Kooijman, S.2
Boon, M.R.3
Rensen, P.C.N.4
Berbée, J.F.P.5
-
90
-
-
84920700786
-
Brown adipose tissue takes up plasma triglycerides mostly after lipolysis
-
Khedoe PPSJ, Hoeke G, Kooijman S, Dijk W, Buijs JT, Kersten S, Havekes LM, Hiemstra PS, Berbée JFP, Boon MR, Rensen PCN. Brown adipose tissue takes up plasma triglycerides mostly after lipolysis. J Lipid Res. 2014;56(1):51-59.
-
(2014)
J Lipid Res
, vol.56
, Issue.1
, pp. 51-59
-
-
Khedoe, P.P.S.J.1
Hoeke, G.2
Kooijman, S.3
Dijk, W.4
Buijs, J.T.5
Kersten, S.6
Havekes, L.M.7
Hiemstra, P.S.8
Berbée, J.F.P.9
Boon, M.R.10
Rensen, P.C.N.11
-
91
-
-
44649099112
-
Downregulation of AMP-activated protein kinase by Cideamediated ubiquitination and degradation in brown adipose tissue
-
Qi J, Gong J, Zhao T, Zhao J, Lam P, Ye J, Li JZ, WuJ, Zhou HM, Li P. Downregulation of AMP-activated protein kinase by Cideamediated ubiquitination and degradation in brown adipose tissue. EMBO J. 2008;27(11):1537-1548.
-
(2008)
EMBO J
, vol.27
, Issue.11
, pp. 1537-1548
-
-
Qi, J.1
Gong, J.2
Zhao, T.3
Zhao, J.4
Lam, P.5
Ye, J.6
Li, J.Z.7
Wu, J.8
Zhou, H.M.9
Li, P.10
-
92
-
-
84894412290
-
Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice
-
Geerling JJ, Boon MR, van der Zon GC, van den Berg SAA, van den Hoek AM, Lombès M, Princen HMG, Havekes LM, Rensen PCN, Guigas B. Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice. Diabetes. 2013;63(3):880-891.
-
(2013)
Diabetes
, vol.63
, Issue.3
, pp. 880-891
-
-
Geerling, J.J.1
Boon, M.R.2
van der Zon, G.C.3
van den Berg, S.A.A.4
van den Hoek, A.M.5
Lombès, M.6
Princen, H.M.G.7
Havekes, L.M.8
Rensen, P.C.N.9
Guigas, B.10
-
93
-
-
18244363982
-
Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes
-
Maeda K, Cao H, Kono K, Gorgun CZ, Furuhashi M, Uysal KT, Cao Q, Atsumi G, Malone H, Krishnan B, Minokoshi Y, Kahn BB, Parker RA, Hotamisligil GS. Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Cell Metab. 2005;1(2):107-119.
-
(2005)
Cell Metab
, vol.1
, Issue.2
, pp. 107-119
-
-
Maeda, K.1
Cao, H.2
Kono, K.3
Gorgun, C.Z.4
Furuhashi, M.5
Uysal, K.T.6
Cao, Q.7
Atsumi, G.8
Malone, H.9
Krishnan, B.10
Minokoshi, Y.11
Kahn, B.B.12
Parker, R.A.13
Hotamisligil, G.S.14
-
94
-
-
67650242165
-
High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity
-
Saito M, Okamatsu-Ogura Y, Matsushita M, Watanabe K, Yoneshiro T, Nio-Kobayashi J, Iwanaga T, Miyagawa M, Kameya T, Nakada K, Kawai Y, Tsujisaki M. High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes. 2009; 58(7):1526-1531.
-
(2009)
Diabetes
, vol.58
, Issue.7
, pp. 1526-1531
-
-
Saito, M.1
Okamatsu-Ogura, Y.2
Matsushita, M.3
Watanabe, K.4
Yoneshiro, T.5
Nio-Kobayashi, J.6
Iwanaga, T.7
Miyagawa, M.8
Kameya, T.9
Nakada, K.10
Kawai, Y.11
Tsujisaki, M.12
-
95
-
-
64349123664
-
Functional brown adipose tissue in healthy adults
-
Virtanen KA, Lidell ME, Orava J, Heglind M, Westergren R, Niemi T, Taittonen M, Laine J, Savisto N-J, Enerbäck S, Nuutila P. Functional brown adipose tissue in healthy adults. N Engl J Med. 2009;360(15):1518-1525.
-
(2009)
N Engl J Med
, vol.360
, Issue.15
, pp. 1518-1525
-
-
Virtanen, K.A.1
Lidell, M.E.2
Orava, J.3
Heglind, M.4
Westergren, R.5
Niemi, T.6
Taittonen, M.7
Laine, J.8
Savisto, N.-J.9
Enerbäck, S.10
Nuutila, P.11
-
96
-
-
79960945989
-
Different metabolic responses of human brown adipose tissue to activation by cold and insulin
-
Orava J, Nuutila P, Lidell ME, Oikonen V, Noponen T, Viljanen T, Scheinin M, Taittonen M, Niemi T, Enerbäck S, Virtanen KA. Different metabolic responses of human brown adipose tissue to activation by cold and insulin. Cell Metab. 2011;14(2):272-279.
-
(2011)
Cell Metab
, vol.14
, Issue.2
, pp. 272-279
-
-
Orava, J.1
Nuutila, P.2
Lidell, M.E.3
Oikonen, V.4
Noponen, T.5
Viljanen, T.6
Scheinin, M.7
Taittonen, M.8
Niemi, T.9
Enerbäck, S.10
Virtanen, K.A.11
-
97
-
-
84856529575
-
Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans
-
Ouellet V, Labbé SM, Blondin DP, Phoenix S, Guérin B, Haman F, Turcotte EE, Richard D, Carpentier AC. Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans. J Clin Invest. 2012;122(2): 545-552.
-
(2012)
J Clin Invest
, vol.122
, Issue.2
, pp. 545-552
-
-
Ouellet, V.1
Labbé, S.M.2
Blondin, D.P.3
Phoenix, S.4
Guérin, B.5
Haman, F.6
Turcotte, E.E.7
Richard, D.8
Carpentier, A.C.9
-
98
-
-
34247485758
-
Low-dose oral propranolol could reduce brown adipose tissue F-18 FDG uptake in patients undergoing PET scans
-
Parysow O, Mollerach AM, Jager V, Racioppi S, San Roman J, Gerbaudo VH. Low-dose oral propranolol could reduce brown adipose tissue F-18 FDG uptake in patients undergoing PET scans. Clin Nucl Med. 2007;32(5):351-357.
-
(2007)
Clin Nucl Med
, vol.32
, Issue.5
, pp. 351-357
-
-
Parysow, O.1
Mollerach, A.M.2
Jager, V.3
Racioppi, S.4
San Roman, J.5
Gerbaudo, V.H.6
-
99
-
-
84920627180
-
Activation of human brown adipose tissue by a b3-adrenergic receptor agonist
-
Cypess AM, Weiner LS, Roberts-Toler C, Franquet Elía E, Kessler SH, Kahn PA, English J, Chatman K, Trauger SA, Doria A, Kolodny GM. Activation of human brown adipose tissue by a b3-adrenergic receptor agonist. Cell Metab. 2015;21(1):33-38.
-
(2015)
Cell Metab
, vol.21
, Issue.1
, pp. 33-38
-
-
Cypess, A.M.1
Weiner, L.S.2
Roberts-Toler, C.3
Franquet Elía, E.4
Kessler, S.H.5
Kahn, P.A.6
English, J.7
Chatman, K.8
Trauger, S.A.9
Doria, A.10
Kolodny, G.M.11
-
100
-
-
84936773588
-
Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes
-
Xue R, Lynes MD, Dreyfuss JM, Shamsi F, Schulz TJ, Zhang H, Huang TL, Townsend KL, Li Y, Takahashi H, Weiner LS, White AP, Lynes MS, Rubin LL, Goodyear LJ, Cypess AM, Tseng Y-H. Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes. Nat Med. 2015;21(7):760-768.
-
(2015)
Nat Med
, vol.21
, Issue.7
, pp. 760-768
-
-
Xue, R.1
Lynes, M.D.2
Dreyfuss, J.M.3
Shamsi, F.4
Schulz, T.J.5
Zhang, H.6
Huang, T.L.7
Townsend, K.L.8
Li, Y.9
Takahashi, H.10
Weiner, L.S.11
White, A.P.12
Lynes, M.S.13
Rubin, L.L.14
Goodyear, L.J.15
Cypess, A.M.16
Tseng, Y.-H.17
-
101
-
-
84936771989
-
Genetic and functional characterization of clonally derived adult human brown adipocytes
-
Shinoda K, Luijten IHN, HasegawaY, Hong H, Sonne SB, Kim M, Xue R, Chondronikola M, Cypess AM, Tseng Y-H, Nedergaard J, Sidossis LS, Kajimura S. Genetic and functional characterization of clonally derived adult human brown adipocytes. Nat Med. 2015;21(4):389-394.
-
(2015)
Nat Med
, vol.21
, Issue.4
, pp. 389-394
-
-
Shinoda, K.1
Luijten, I.H.N.2
Hasegawa, Y.3
Hong, H.4
Sonne, S.B.5
Kim, M.6
Xue, R.7
Chondronikola, M.8
Cypess, A.M.9
Tseng, Y.-H.10
Nedergaard, J.11
Sidossis, L.S.12
Kajimura, S.13
-
102
-
-
84877331455
-
Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat
-
Cypess AM, White AP, Vernochet C, Schulz TJ, Xue R, Sass CA, Huang TL, Roberts-Toler C, Weiner LS, Sze C, Chacko AT, Deschamps LN, Herder LM, Truchan N, Glasgow AL, Holman AR, Gavrila A, Hasselgren P-O, Mori MA, Molla M, Tseng Y-H. Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat. Nat Med. 2013; 19(5):635-639.
-
(2013)
Nat Med
, vol.19
, Issue.5
, pp. 635-639
-
-
Cypess, A.M.1
White, A.P.2
Vernochet, C.3
Schulz, T.J.4
Xue, R.5
Sass, C.A.6
Huang, T.L.7
Roberts-Toler, C.8
Weiner, L.S.9
Sze, C.10
Chacko, A.T.11
Deschamps, L.N.12
Herder, L.M.13
Truchan, N.14
Glasgow, A.L.15
Holman, A.R.16
Gavrila, A.17
Hasselgren, P.-O.18
Mori, M.A.19
Molla, M.20
Tseng, Y.-H.21
more..
-
103
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
Cypess AM, Lehman S, Williams G, Tal I, Rodman D, Goldfine AB, Kuo FC, Palmer EL, Tseng Y-H, Doria A, Kolodny GM, Kahn CR. Identification and importance of brown adipose tissue in adult humans. N Engl J Med. 2009;360(15):1509-1517.
-
(2009)
N Engl J Med
, vol.360
, Issue.15
, pp. 1509-1517
-
-
Cypess, A.M.1
Lehman, S.2
Williams, G.3
Tal, I.4
Rodman, D.5
Goldfine, A.B.6
Kuo, F.C.7
Palmer, E.L.8
Tseng, Y.-H.9
Doria, A.10
Kolodny, G.M.11
Kahn, C.R.12
-
104
-
-
70350536563
-
Brown adipose tissue and seasonal variation in humans
-
Au-Yong ITH, Thorn N, Ganatra R, Perkins AC, Symonds ME. Brown adipose tissue and seasonal variation in humans. Diabetes. 2009;58(11):2583-2587.
-
(2009)
Diabetes
, vol.58
, Issue.11
, pp. 2583-2587
-
-
Au-Yong, I.T.H.1
Thorn, N.2
Ganatra, R.3
Perkins, A.C.4
Symonds, M.E.5
-
105
-
-
84934317617
-
Selective impairment of glucose but not fatty acid or oxidative metabolism in brown adipose tissue of subjects with type 2 diabetes
-
Blondin DP, Labbé SM, Noll C, Kunach M, Phoenix S, Guérin B, Turcotte E E, Haman F, Richard D, Carpentier AC. Selective impairment of glucose but not fatty acid or oxidative metabolism in brown adipose tissue of subjects with type 2 diabetes. Diabetes. 2015;64(7):2388-2397.
-
(2015)
Diabetes
, vol.64
, Issue.7
, pp. 2388-2397
-
-
Blondin, D.P.1
Labbé, S.M.2
Noll, C.3
Kunach, M.4
Phoenix, S.5
Guérin, B.6
Turcotte, E.E.7
Haman, F.8
Richard, D.9
Carpentier, A.C.10
-
106
-
-
84862495484
-
Increase in brown adipose tissue activity after weight loss in morbidly obese subjects
-
Vijgen GH, Bouvy ND, Teule GJ, Brans B, Hoeks J, Schrauwen P, van Marken Lichtenbelt WD. Increase in brown adipose tissue activity after weight loss in morbidly obese subjects. J Clin Endocrinol Metab. 2012;97(7):E1229-E1233.
-
(2012)
J Clin Endocrinol Metab
, vol.97
, Issue.7
, pp. E1229-E1233
-
-
Vijgen, G.H.1
Bouvy, N.D.2
Teule, G.J.3
Brans, B.4
Hoeks, J.5
Schrauwen, P.6
van Marken Lichtenbelt, W.D.7
-
107
-
-
84881260642
-
Cold acclimation recruits human brown fat and increases nonshivering thermogenesis
-
van der Lans AAJJ, Hoeks J, Brans B, Vijgen GHEJ, Visser MGW, Vosselman MJ, Hansen J, J örgensen JA, Wu J, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD. Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. J Clin Invest. 2013;123(8):3395-3403.
-
(2013)
J Clin Invest
, vol.123
, Issue.8
, pp. 3395-3403
-
-
van der Lans, A.A.J.J.1
Hoeks, J.2
Brans, B.3
Vijgen, G.H.E.J.4
Visser, M.G.W.5
Vosselman, M.J.6
Hansen, J.7
Jörgensen, J.A.8
Wu, J.9
Mottaghy, F.M.10
Schrauwen, P.11
van Marken Lichtenbelt, W.D.12
-
108
-
-
84955587698
-
Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice
-
Min SY, Kady J, Nam M, Rojas-Rodriguez R, Berkenwald A, Kim JH, Noh H-L, Kim JK, Cooper MP, Fitzgibbons T, Brehm MA, Corvera S. Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice. Nat Med. 2016;22(3):312-318.
-
(2016)
Nat Med
, vol.22
, Issue.3
, pp. 312-318
-
-
Min, S.Y.1
Kady, J.2
Nam, M.3
Rojas-Rodriguez, R.4
Berkenwald, A.5
Kim, J.H.6
Noh, H.-L.7
Kim, J.K.8
Cooper, M.P.9
Fitzgibbons, T.10
Brehm, M.A.11
Corvera, S.12
-
109
-
-
84911896533
-
Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans
-
Chondronikola M, Volpi E, Børsheim E, Porter C, Annamalai P, Enerbäck S, LidellME, Saraf MK, Labbe SM, HurrenNM, Yfanti C, Chao T, Andersen CR, Cesani F, Hawkins H, Sidossis LS. Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans. Diabetes. 2014;63(12):4089-4099.
-
(2014)
Diabetes
, vol.63
, Issue.12
, pp. 4089-4099
-
-
Chondronikola, M.1
Volpi, E.2
Børsheim, E.3
Porter, C.4
Annamalai, P.5
Enerbäck, S.6
Lidell, M.E.7
Saraf, M.K.8
Labbe, S.M.9
Hurren, N.M.10
Yfanti, C.11
Chao, T.12
Andersen, C.R.13
Cesani, F.14
Hawkins, H.15
Sidossis, L.S.16
-
110
-
-
84907973405
-
Temperatureacclimated brown adipose tissue modulates insulin sensitivity in humans
-
Lee P, Smith S, Linderman J, Courville AB, Brychta RJ, Dieckmann W, Werner CD, Chen KY, Celi FS. Temperatureacclimated brown adipose tissue modulates insulin sensitivity in humans. Diabetes. 2014;63(11):3686-3698.
-
(2014)
Diabetes
, vol.63
, Issue.11
, pp. 3686-3698
-
-
Lee, P.1
Smith, S.2
Linderman, J.3
Courville, A.B.4
Brychta, R.J.5
Dieckmann, W.6
Werner, C.D.7
Chen, K.Y.8
Celi, F.S.9
-
111
-
-
84982797849
-
Supraclavicular brown adipose tissue 18F-FDG uptake and cardiovascular disease
-
Takx RA, Ishai A, Truong QA, MacNabb MH, Scherrer-Crosbie M, Tawakol A. Supraclavicular brown adipose tissue 18F-FDG uptake and cardiovascular disease. J Nucl Med. 2016;57(8): 1221-1225.
-
(2016)
J Nucl Med
, vol.57
, Issue.8
, pp. 1221-1225
-
-
Takx, R.A.1
Ishai, A.2
Truong, Q.A.3
MacNabb, M.H.4
Scherrer-Crosbie, M.5
Tawakol, A.6
-
112
-
-
84939496204
-
High prevalence of cardiovascular disease in South Asians: central role for brown adipose tissue?
-
Boon MR, Bakker LEH, van der Linden RAD, van Ouwerkerk AF, de Goeje PL, Counotte J, Jazet IM, Rensen PCN. High prevalence of cardiovascular disease in South Asians: central role for brown adipose tissue? Crit Rev Clin Lab Sci. 2015;52(3): 150-157.
-
(2015)
Crit Rev Clin Lab Sci
, vol.52
, Issue.3
, pp. 150-157
-
-
Boon, M.R.1
Bakker, L.E.H.2
van der Linden, R.A.D.3
van Ouwerkerk, A.F.4
de Goeje, P.L.5
Counotte, J.6
Jazet, I.M.7
Rensen, P.C.N.8
-
113
-
-
84962028277
-
Brown adipose tissue exhibits a glucose-responsive thermogenic biorhythm in humans
-
Lee P, Bova R, Schofield L, Bryant W, Dieckmann W, Slattery A, Govendir MA, Emmett L, Greenfield JR. Brown adipose tissue exhibits a glucose-responsive thermogenic biorhythm in humans. Cell Metab. 2016;23(4):602-609.
-
(2016)
Cell Metab
, vol.23
, Issue.4
, pp. 602-609
-
-
Lee, P.1
Bova, R.2
Schofield, L.3
Bryant, W.4
Dieckmann, W.5
Slattery, A.6
Govendir, M.A.7
Emmett, L.8
Greenfield, J.R.9
-
114
-
-
84925519476
-
Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance
-
HanssenMJW, Wierts R, Hoeks J, Gemmink A, Brans B, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD. Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance. Diabetologia. 2014;58(3):586-595.
-
(2014)
Diabetologia
, vol.58
, Issue.3
, pp. 586-595
-
-
Hanssen, M.J.W.1
Wierts, R.2
Hoeks, J.3
Gemmink, A.4
Brans, B.5
Mottaghy, F.M.6
Schrauwen, P.7
van Marken Lichtenbelt, W.D.8
-
115
-
-
84919779595
-
Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity
-
Boon MR, Kooijman S, van Dam AD, Pelgrom LR, Berbée JFP, Visseren CAR, van Aggele RC, van den Hoek AM, Sips HCM, Lombès M, Havekes LM, Tamsma JT, Guigas B, Meijer OC, Jukema JW, Rensen PCN. Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity. FASEB J. 2014;28(12):5361-5375.
-
(2014)
FASEB J
, vol.28
, Issue.12
, pp. 5361-5375
-
-
Boon, M.R.1
Kooijman, S.2
van Dam, A.D.3
Pelgrom, L.R.4
Berbée, J.F.P.5
Visseren, C.A.R.6
van Aggele, R.C.7
van den Hoek, A.M.8
Sips, H.C.M.9
Lombès, M.10
Havekes, L.M.11
Tamsma, J.T.12
Guigas, B.13
Meijer, O.C.14
Jukema, J.W.15
Rensen, P.C.N.16
-
116
-
-
84933545180
-
Salsalate activates brown adipose tissue in mice
-
van Dam AD, Nahon KJ, Kooijman S, van den Berg SM, Kanhai AA, Kikuchi T, Heemskerk MM, van Harmelen V, Lombès M, van den Hoek AM, deWinther MPJ, Lutgens E, Guigas B, Rensen PCN, Boon MR. Salsalate activates brown adipose tissue in mice. Diabetes. 2014;64(5):1544-1554.
-
(2014)
Diabetes
, vol.64
, Issue.5
, pp. 1544-1554
-
-
van Dam, A.D.1
Nahon, K.J.2
Kooijman, S.3
van den Berg, S.M.4
Kanhai, A.A.5
Kikuchi, T.6
Heemskerk, M.M.7
van Harmelen, V.8
Lombès, M.9
van den Hoek, A.M.10
deWinther, M.P.J.11
Lutgens, E.12
Guigas, B.13
Rensen, P.C.N.14
Boon, M.R.15
-
117
-
-
84942991914
-
Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice
-
Kooijman S, Wang Y, Parlevliet ET, Boon MR, Edelschaap D, Snaterse G, Pijl H, Romijn JA, Rensen PCN. Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice. Diabetologia. 2015;58(11):2637-2646.
-
(2015)
Diabetologia
, vol.58
, Issue.11
, pp. 2637-2646
-
-
Kooijman, S.1
Wang, Y.2
Parlevliet, E.T.3
Boon, M.R.4
Edelschaap, D.5
Snaterse, G.6
Pijl, H.7
Romijn, J.A.8
Rensen, P.C.N.9
-
118
-
-
79957920754
-
Inflammatory links between obesity and metabolic disease
-
Lumeng CN, Saltiel AR. Inflammatory links between obesity and metabolic disease. J Clin Invest. 2011;121(6):2111-2117.
-
(2011)
J Clin Invest
, vol.121
, Issue.6
, pp. 2111-2117
-
-
Lumeng, C.N.1
Saltiel, A.R.2
-
119
-
-
79151484704
-
Adipokines in inflammation and metabolic disease
-
Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol. 2011; 11(2):85-97.
-
(2011)
Nat Rev Immunol
, vol.11
, Issue.2
, pp. 85-97
-
-
Ouchi, N.1
Parker, J.L.2
Lugus, J.J.3
Walsh, K.4
-
120
-
-
80355133234
-
Macrophage-mediated inflammation in metabolic disease
-
Chawla A, Nguyen KD, Goh YPS. Macrophage-mediated inflammation in metabolic disease. Nat Rev Immunol. 2011;11(11): 738-749.
-
(2011)
Nat Rev Immunol
, vol.11
, Issue.11
, pp. 738-749
-
-
Chawla, A.1
Nguyen, K.D.2
Goh, Y.P.S.3
-
121
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993;259(5091):87-91.
-
(1993)
Science
, vol.259
, Issue.5091
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
122
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003;112(12): 1796-1808.
-
(2003)
J Clin Invest
, vol.112
, Issue.12
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.6
-
123
-
-
84878785347
-
Immunological goings-on in visceral adipose tissue
-
Mathis D. Immunological goings-on in visceral adipose tissue. Cell Metab. 2013;17(6):851-859.
-
(2013)
Cell Metab
, vol.17
, Issue.6
, pp. 851-859
-
-
Mathis, D.1
-
124
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest. 2007;117(1):175-184.
-
(2007)
J Clin Invest
, vol.117
, Issue.1
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
126
-
-
0034770292
-
Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle
-
Perreault M, Marette A. Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle. Nat Med. 2001;7(10):1138-1143.
-
(2001)
Nat Med
, vol.7
, Issue.10
, pp. 1138-1143
-
-
Perreault, M.1
Marette, A.2
-
127
-
-
52749092267
-
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
-
Patsouris D, Li P-P, Thapar D, Chapman J, Olefsky JM, Neels JG. Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metab. 2008;8(4):301-309.
-
(2008)
Cell Metab
, vol.8
, Issue.4
, pp. 301-309
-
-
Patsouris, D.1
Li, P.-P.2
Thapar, D.3
Chapman, J.4
Olefsky, J.M.5
Neels, J.G.6
-
128
-
-
53149119231
-
Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding
-
Elgazar-Carmon V, Rudich A, Hadad N, Levy R. Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding. J Lipid Res. 2008;49(9):1894-1903.
-
(2008)
J Lipid Res
, vol.49
, Issue.9
, pp. 1894-1903
-
-
Elgazar-Carmon, V.1
Rudich, A.2
Hadad, N.3
Levy, R.4
-
129
-
-
84868671526
-
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
-
Talukdar S, Oh DY, Bandyopadhyay G, Li D, Xu J, McNelis J, Lu M, Li P, Yan Q, Zhu Y, Ofrecio J, Lin M, Brenner MB, Olefsky JM. Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med. 2012;18(9):1407-1412.
-
(2012)
Nat Med
, vol.18
, Issue.9
, pp. 1407-1412
-
-
Talukdar, S.1
Oh, D.Y.2
Bandyopadhyay, G.3
Li, D.4
Xu, J.5
McNelis, J.6
Lu, M.7
Li, P.8
Yan, Q.9
Zhu, Y.10
Ofrecio, J.11
Lin, M.12
Brenner, M.B.13
Olefsky, J.M.14
-
130
-
-
79953815551
-
Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis
-
Wu D, Molofsky AB, Liang H-E, Ricardo-Gonzalez RR, Jouihan HA, Bando JK, Chawla A, Locksley RM. Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis. Science. 2011;332(6026):243-247.
-
(2011)
Science
, vol.332
, Issue.6026
, pp. 243-247
-
-
Wu, D.1
Molofsky, A.B.2
Liang, H.-E.3
Ricardo-Gonzalez, R.R.4
Jouihan, H.A.5
Bando, J.K.6
Chawla, A.7
Locksley, R.M.8
-
131
-
-
34347354309
-
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
-
Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Red Eagle A, Vats D, Brombacher F, Ferrante AW, Chawla A. Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature. 2007;447(7148):1116-1120.
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
Red Eagle, A.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
132
-
-
70349563430
-
Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators
-
Duffaut C, Zakaroff-Girard A, Bourlier V, Decaunes P, Maumus M, Chiotasso P, Sengenès C, Lafontan M, Galitzky J, Bouloumié A. Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators. Arterioscler Thromb Vasc Biol. 2009; 29(10):1608-1614.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, Issue.10
, pp. 1608-1614
-
-
Duffaut, C.1
Zakaroff-Girard, A.2
Bourlier, V.3
Decaunes, P.4
Maumus, M.5
Chiotasso, P.6
Sengenès, C.7
Lafontan, M.8
Galitzky, J.9
Bouloumié, A.10
-
133
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
Feuerer M, Herrero L, Cipolletta D, Naaz A, Wong J, Nayer A, Lee J, Goldfine AB, Benoist C, Shoelson S, Mathis D. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med. 2009;15(8):930-939.
-
(2009)
Nat Med
, vol.15
, Issue.8
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
Naaz, A.4
Wong, J.5
Nayer, A.6
Lee, J.7
Goldfine, A.B.8
Benoist, C.9
Shoelson, S.10
Mathis, D.11
-
134
-
-
68349150756
-
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Ueki K, Sugiura S, Yoshimura K, Kadowaki T, Nagai R. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med. 2009;15(8):914-920.
-
(2009)
Nat Med
, vol.15
, Issue.8
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Eto, K.4
Yamashita, H.5
Ohsugi, M.6
Otsu, M.7
Hara, K.8
Ueki, K.9
Sugiura, S.10
Yoshimura, K.11
Kadowaki, T.12
Nagai, R.13
-
135
-
-
84866107224
-
Lymphocytes in obesity-related adipose tissue inflammation
-
Chatzigeorgiou A, Karalis KP, Bornstein SR, Chavakis T. Lymphocytes in obesity-related adipose tissue inflammation. Diabetologia. 2012;55(10):2583-2592.
-
(2012)
Diabetologia
, vol.55
, Issue.10
, pp. 2583-2592
-
-
Chatzigeorgiou, A.1
Karalis, K.P.2
Bornstein, S.R.3
Chavakis, T.4
-
136
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
Winer S, Chan Y, Paltser G, Truong D, Tsui H, Bahrami J, Dorfman R, Wang Y, Zielenski J, Mastronardi F, Maezawa Y, Drucker DJ, Engleman E, Winer D, Dosch HM. Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med. 2009;15(8):921-929.
-
(2009)
Nat Med
, vol.15
, Issue.8
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
Truong, D.4
Tsui, H.5
Bahrami, J.6
Dorfman, R.7
Wang, Y.8
Zielenski, J.9
Mastronardi, F.10
Maezawa, Y.11
Drucker, D.J.12
Engleman, E.13
Winer, D.14
Dosch, H.M.15
-
137
-
-
84866358717
-
The adaptive immune system as a fundamental regulator of adipose tissue inflammation and insulin resistance
-
Winer S, Winer DA. The adaptive immune system as a fundamental regulator of adipose tissue inflammation and insulin resistance. Immunol Cell Biol. 2012;90(8):755-762.
-
(2012)
Immunol Cell Biol
, vol.90
, Issue.8
, pp. 755-762
-
-
Winer, S.1
Winer, D.A.2
-
138
-
-
85027938385
-
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
-
Winer DA, Winer S, Shen L, Wadia PP, Yantha J, Paltser G, Tsui H, Wu P, Davidson MG, Alonso MN, Leong HX, Glassford A, Caimol M, Kenkel JA, Tedder TF, McLaughlin T, Miklos DB, Dosch HM, Engleman EG. B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. Nat Med. 2011;17(5):610-617.
-
(2011)
Nat Med
, vol.17
, Issue.5
, pp. 610-617
-
-
Winer, D.A.1
Winer, S.2
Shen, L.3
Wadia, P.P.4
Yantha, J.5
Paltser, G.6
Tsui, H.7
Wu, P.8
Davidson, M.G.9
Alonso, M.N.10
Leong, H.X.11
Glassford, A.12
Caimol, M.13
Kenkel, J.A.14
Tedder, T.F.15
McLaughlin, T.16
Miklos, D.B.17
Dosch, H.M.18
Engleman, E.G.19
-
139
-
-
68349160704
-
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
-
Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, Shi G-P. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med. 2009;15(8):940-945.
-
(2009)
Nat Med
, vol.15
, Issue.8
, pp. 940-945
-
-
Liu, J.1
Divoux, A.2
Sun, J.3
Zhang, J.4
Clément, K.5
Glickman, J.N.6
Sukhova, G.K.7
Wolters, P.J.8
Du, J.9
Gorgun, C.Z.10
Doria, A.11
Libby, P.12
Blumberg, R.S.13
Kahn, B.B.14
Hotamisligil, G.S.15
Shi, G.-P.16
-
140
-
-
84955359487
-
Thermoneutral housing accelerates metabolic inflammation to potentiate atherosclerosis but not insulin resistance [published correction appears in Cell Metab 2016;23(2):386]
-
Tian XY, Ganeshan K, Hong C, Nguyen KD, Qiu Y, Kim J, Tangirala RK, Tontonoz P, Chawla A. Thermoneutral housing accelerates metabolic inflammation to potentiate atherosclerosis but not insulin resistance [published correction appears in Cell Metab. 2016;23(2):386]. Cell Metab. 2016;23(1):165-178.
-
(2016)
Cell Metab
, vol.23
, Issue.1
, pp. 165-178
-
-
Tian, X.Y.1
Ganeshan, K.2
Hong, C.3
Nguyen, K.D.4
Qiu, Y.5
Kim, J.6
Tangirala, R.K.7
Tontonoz, P.8
Chawla, A.9
-
141
-
-
84928929483
-
Thermoneutral housing is a critical factor for immune function and diet-induced obesity in C57BL/6 nude mice
-
Stemmer K, Kotzbeck P, Zani F, Bauer M, Neff C, Müller TD, Pfluger PT, Seeley RJ, Divanovic S. Thermoneutral housing is a critical factor for immune function and diet-induced obesity in C57BL/6 nude mice. Int J Obes. 2014;39(5):791-797.
-
(2014)
Int J Obes
, vol.39
, Issue.5
, pp. 791-797
-
-
Stemmer, K.1
Kotzbeck, P.2
Zani, F.3
Bauer, M.4
Neff, C.5
Müller, T.D.6
Pfluger, P.T.7
Seeley, R.J.8
Divanovic, S.9
-
142
-
-
84960864098
-
The circadian clock in the ventromedial hypothalamus controls cyclic energy expenditure
-
Orozco-Solis R, Aguilar-Arnal L, Murakami M, Peruquetti R, Ramadori G, Coppari R, Sassone-Corsi P. The circadian clock in the ventromedial hypothalamus controls cyclic energy expenditure. Cell Metab. 2016;23(3):467-478.
-
(2016)
Cell Metab
, vol.23
, Issue.3
, pp. 467-478
-
-
Orozco-Solis, R.1
Aguilar-Arnal, L.2
Murakami, M.3
Peruquetti, R.4
Ramadori, G.5
Coppari, R.6
Sassone-Corsi, P.7
-
143
-
-
84904043360
-
Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK
-
Martínez de Morentin PB, González-García I, Martins L, Lage R, Fernández-Mallo D, Martínez-Sánchez N, Ruíz-Pino F, Liu J, Morgan DA, Pinilla L, Gallego R, Saha AK, Kalsbeek A, Fliers E, Bisschop PH, Diéguez C, Nogueiras R, Rahmouni K, Tena-Sempere M, Ló pez M. Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK. Cell Metab. 2014;20(1): 41-53.
-
(2014)
Cell Metab
, vol.20
, Issue.1
, pp. 41-53
-
-
Martínez de Morentin, P.B.1
González-García, I.2
Martins, L.3
Lage, R.4
Fernández-Mallo, D.5
Martínez-Sánchez, N.6
Ruíz-Pino, F.7
Liu, J.8
Morgan, D.A.9
Pinilla, L.10
Gallego, R.11
Saha, A.K.12
Kalsbeek, A.13
Fliers, E.14
Bisschop, P.H.15
Diéguez, C.16
Nogueiras, R.17
Rahmouni, K.18
Tena-Sempere, M.19
López, M.20
more..
-
144
-
-
66449086930
-
Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity
-
Rogers NH, Perfield JW II, Strissel KJ, Obin MS, Greenberg AS. Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity. Endocrinology. 2009;150(5):2161-2168.
-
(2009)
Endocrinology
, vol.150
, Issue.5
, pp. 2161-2168
-
-
Rogers, N.H.1
Perfield, J.W.2
Strissel, K.J.3
Obin, M.S.4
Greenberg, A.S.5
-
145
-
-
84862008430
-
Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet
-
Hatori M, Vollmers C, Zarrinpar A, DiTacchio L, Bushong EA, Gill S, Leblanc M, Chaix A, Joens M, Fitzpatrick JA, Ellisman MH, Panda S. Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell Metab. 2012;15(6):848-860.
-
(2012)
Cell Metab
, vol.15
, Issue.6
, pp. 848-860
-
-
Hatori, M.1
Vollmers, C.2
Zarrinpar, A.3
DiTacchio, L.4
Bushong, E.A.5
Gill, S.6
Leblanc, M.7
Chaix, A.8
Joens, M.9
Fitzpatrick, J.A.10
Ellisman, M.H.11
Panda, S.12
-
146
-
-
84907495079
-
GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK
-
Beiroa D, Imbernon M, Gallego R, Senra A, Herranz D, Villarroya F, Serrano M, Fernø J, Salvador J, Escalada J, Dieguez C, Lopez M, Frühbeck G, Nogueiras R. GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK. Diabetes. 2014;63(10):3346-3358.
-
(2014)
Diabetes
, vol.63
, Issue.10
, pp. 3346-3358
-
-
Beiroa, D.1
Imbernon, M.2
Gallego, R.3
Senra, A.4
Herranz, D.5
Villarroya, F.6
Serrano, M.7
Fernø, J.8
Salvador, J.9
Escalada, J.10
Dieguez, C.11
Lopez, M.12
Frühbeck, G.13
Nogueiras, R.14
-
147
-
-
84866055251
-
Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes
-
Lee YS, Park MS, Choung JS, Kim SS, Oh HH, Choi CS, Ha SY, Kang Y, Kim Y, Jun HS. Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes. Diabetologia. 2012;55(9):2456-2468.
-
(2012)
Diabetologia
, vol.55
, Issue.9
, pp. 2456-2468
-
-
Lee, Y.S.1
Park, M.S.2
Choung, J.S.3
Kim, S.S.4
Oh, H.H.5
Choi, C.S.6
Ha, S.Y.7
Kang, Y.8
Kim, Y.9
Jun, H.S.10
-
148
-
-
84892402412
-
Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration
-
Wang Y, Parlevliet ET, Geerling JJ, van der Tuin SJL, Zhang H, Bieghs V, Jawad AHM, Shiri-Sverdlov R, Bot I, de Jager SCA, Havekes LM, Romijn JA, Willems van Dijk K, Rensen PCN. Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration. Br J Pharmacol. 2014;171(3):723-734.
-
(2014)
Br J Pharmacol
, vol.171
, Issue.3
, pp. 723-734
-
-
Wang, Y.1
Parlevliet, E.T.2
Geerling, J.J.3
van der Tuin, S.J.L.4
Zhang, H.5
Bieghs, V.6
Jawad, A.H.M.7
Shiri-Sverdlov, R.8
Bot, I.9
de Jager, S.C.A.10
Havekes, L.M.11
Romijn, J.A.12
Willems van Dijk, K.13
Rensen, P.C.N.14
-
149
-
-
84892613505
-
Time-course microarrays reveal modulation of developmental, lipid metabolism and immune gene networks in intrascapular brown adipose tissue during the development of diet-induced obesity
-
McGregor RA, Kwon EY, Shin SK, Jung UJ, Kim E, Park JHY, Yu R, Yun JW, Choi MS. Time-course microarrays reveal modulation of developmental, lipid metabolism and immune gene networks in intrascapular brown adipose tissue during the development of diet-induced obesity. Int J Obes. 2013;37(12):1524-1531.
-
(2013)
Int J Obes
, vol.37
, Issue.12
, pp. 1524-1531
-
-
McGregor, R.A.1
Kwon, E.Y.2
Shin, S.K.3
Jung, U.J.4
Kim, E.5
Park, J.H.Y.6
Yu, R.7
Yun, J.W.8
Choi, M.S.9
-
150
-
-
84900554588
-
Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration
-
Bae J, Ricciardi CJ, Esposito D, Komarnytsky S, Hu P, Curry BJ, Brown PL, Gao Z, Biggerstaff JP, Chen J, Zhao L. Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration. Am J Physiol Cell Physiol. 2014; 306(10):C918-C930.
-
(2014)
Am J Physiol Cell Physiol
, vol.306
, Issue.10
, pp. C918-C930
-
-
Bae, J.1
Ricciardi, C.J.2
Esposito, D.3
Komarnytsky, S.4
Hu, P.5
Curry, B.J.6
Brown, P.L.7
Gao, Z.8
Biggerstaff, J.P.9
Chen, J.10
Zhao, L.11
-
151
-
-
84962240969
-
M1-M2 balancing act in white adipose tissue browning-a new role for RIP140
-
Liu P-S, Lin Y-W, Burton FH, Wei L-N. M1-M2 balancing act in white adipose tissue browning-a new role for RIP140. Adipocyte. 2015;4(2):146-148.
-
(2015)
Adipocyte
, vol.4
, Issue.2
, pp. 146-148
-
-
Liu, P.-S.1
Lin, Y.-W.2
Burton, F.H.3
Wei, L.-N.4
-
152
-
-
0037311624
-
Catecholamines in a macrophage cell line
-
Brown SW, MeyersRT, BrennanKM, Rumble JM, Narasimhachari N, Perozzi EF, Ryan JJ, Stewart JK, Fischer-Stenger K. Catecholamines in a macrophage cell line. J Neuroimmunol. 2003;135(1-2): 47-55.
-
(2003)
J Neuroimmunol
, vol.135
, Issue.1-2
, pp. 47-55
-
-
Brown, S.W.1
Meyers, R.T.2
Brennan, K.M.3
Rumble, J.M.4
Narasimhachari, N.5
Perozzi, E.F.6
Ryan, J.J.7
Stewart, J.K.8
Fischer-Stenger, K.9
-
153
-
-
84874114458
-
Adrenal hormone deprivation affects macrophage catecholamine metabolism and b2-adrenoceptor density, but not propranolol stimulation of tumour necrosis factor-α production
-
Stanojević S, Dimitrijević M, Kustrimović N, Mitić K, Vujić V, Leposavić G. Adrenal hormone deprivation affects macrophage catecholamine metabolism and b2-adrenoceptor density, but not propranolol stimulation of tumour necrosis factor-α production. Exp Physiol. 2013;98(3):665-678.
-
(2013)
Exp Physiol
, vol.98
, Issue.3
, pp. 665-678
-
-
Stanojević, S.1
Dimitrijević, M.2
Kustrimović, N.3
Mitić, K.4
Vujić, V.5
Leposavić, G.6
-
154
-
-
84906938319
-
Induction of M2 regulatory macrophages through the b2-αdrenergic receptor with protection during endotoxemia and acute lung injury
-
Grailer JJ, Haggadone MD, Sarma JV, Zetoune FS, Ward PA. Induction of M2 regulatory macrophages through the b2-αdrenergic receptor with protection during endotoxemia and acute lung injury. J Innate Immun. 2014;6(5):607-618.
-
(2014)
J Innate Immun
, vol.6
, Issue.5
, pp. 607-618
-
-
Grailer, J.J.1
Haggadone, M.D.2
Sarma, J.V.3
Zetoune, F.S.4
Ward, P.A.5
-
155
-
-
84925873107
-
Immune regulation of metabolic homeostasis in health and disease
-
Brestoff JR, Artis D. Immune regulation of metabolic homeostasis in health and disease. Cell. 2015;161(1):146-160.
-
(2015)
Cell
, vol.161
, Issue.1
, pp. 146-160
-
-
Brestoff, J.R.1
Artis, D.2
-
156
-
-
84922934617
-
Adipose tissue: ILC2 crank up the heat
-
Flach M, Diefenbach A. Adipose tissue: ILC2 crank up the heat. Cell Metab. 2015;21(2):152-153.
-
(2015)
Cell Metab
, vol.21
, Issue.2
, pp. 152-153
-
-
Flach, M.1
Diefenbach, A.2
-
157
-
-
84991467178
-
IL-33-driven ILC2/eosinophil axis in fat is induced by sympathetic tone and suppressed by obesity
-
Ding X, Luo Y, Zhang X, ZhengH, Yang X, Yang X, LiuM. IL-33-driven ILC2/eosinophil axis in fat is induced by sympathetic tone and suppressed by obesity. J Endocrinol. 2016;231(1):35-48.
-
(2016)
J Endocrinol
, vol.231
, Issue.1
, pp. 35-48
-
-
Ding, X.1
Luo, Y.2
Zhang, X.3
Zheng, H.4
Yang, X.5
Yang, X.6
Liu, M.7
-
158
-
-
84990845574
-
Caloric restriction leads to browning of white adipose tissue through type 2 immune signaling
-
Fabbiano S, Suárez-Zamorano N, Rigo D, Veyrat-Durebex C, Stevanovic Dokic A, Colin DJ, Trajkovski M. Caloric restriction leads to browning of white adipose tissue through type 2 immune signaling. Cell Metab. 2016;24(3):434-446.
-
(2016)
Cell Metab
, vol.24
, Issue.3
, pp. 434-446
-
-
Fabbiano, S.1
Suárez-Zamorano, N.2
Rigo, D.3
Veyrat-Durebex, C.4
Stevanovic Dokic, A.5
Colin, D.J.6
Trajkovski, M.7
-
159
-
-
84987786665
-
IRF3 promotes adipose inflammation and insulin resistance and represses browning
-
Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED. IRF3 promotes adipose inflammation and insulin resistance and represses browning. J Clin Invest. 2016;126(8):2839-2854.
-
(2016)
J Clin Invest
, vol.126
, Issue.8
, pp. 2839-2854
-
-
Kumari, M.1
Wang, X.2
Lantier, L.3
Lyubetskaya, A.4
Eguchi, J.5
Kang, S.6
Tenen, D.7
Roh, H.C.8
Kong, X.9
Kazak, L.10
Ahmad, R.11
Rosen, E.D.12
-
160
-
-
84946050866
-
Activation of Toll-like receptor 4 (TLR4) attenuates adaptive thermogenesis via endoplasmic reticulum stress
-
Okla M, Wang W, Kang I, Pashaj A, Carr T, Chung S. Activation of Toll-like receptor 4 (TLR4) attenuates adaptive thermogenesis via endoplasmic reticulum stress. J Biol Chem. 2015;290(44): 26476-26490.
-
(2015)
J Biol Chem
, vol.290
, Issue.44
, pp. 26476-26490
-
-
Okla, M.1
Wang, W.2
Kang, I.3
Pashaj, A.4
Carr, T.5
Chung, S.6
-
161
-
-
84903989695
-
IRF4 is a key thermogenic transcriptional partner of PGC-1a
-
Kong X, Banks A, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng Y-H, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, Rosen ED. IRF4 is a key thermogenic transcriptional partner of PGC-1a. Cell. 2014;158(1):69-83.
-
(2014)
Cell
, vol.158
, Issue.1
, pp. 69-83
-
-
Kong, X.1
Banks, A.2
Liu, T.3
Kazak, L.4
Rao, R.R.5
Cohen, P.6
Wang, X.7
Yu, S.8
Lo, J.C.9
Tseng, Y.-H.10
Cypess, A.M.11
Xue, R.12
Kleiner, S.13
Kang, S.14
Spiegelman, B.M.15
Rosen, E.D.16
-
162
-
-
77956954197
-
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
-
Satoh T, Takeuchi O, Vandenbon A, Yasuda K, Tanaka Y, Kumagai Y, Miyake T, Matsushita K, Okazaki T, Saitoh T, Honma K, Matsuyama T, Yui K, Tsujimura T, Standley DM, Nakanishi K, Nakai K, Akira S. The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat Immunol. 2010;11(10):936-944.
-
(2010)
Nat Immunol
, vol.11
, Issue.10
, pp. 936-944
-
-
Satoh, T.1
Takeuchi, O.2
Vandenbon, A.3
Yasuda, K.4
Tanaka, Y.5
Kumagai, Y.6
Miyake, T.7
Matsushita, K.8
Okazaki, T.9
Saitoh, T.10
Honma, K.11
Matsuyama, T.12
Yui, K.13
Tsujimura, T.14
Standley, D.M.15
Nakanishi, K.16
Nakai, K.17
Akira, S.18
-
163
-
-
84937760401
-
Hypoxia potentiates tumor necrosis factor-α induced expression of inducible nitric oxide synthase and cyclooxygenase-2 in white and brown adipocytes
-
Bhattacharya I, Domínguez AP, Drägert K, Humar R, Haas E, Battegay EJ. Hypoxia potentiates tumor necrosis factor-α induced expression of inducible nitric oxide synthase and cyclooxygenase-2 in white and brown adipocytes. BiochemBiophys Res Commun. 2015;461(2):287-292.
-
(2015)
BiochemBiophys Res Commun
, vol.461
, Issue.2
, pp. 287-292
-
-
Bhattacharya, I.1
Domínguez, A.P.2
Drägert, K.3
Humar, R.4
Haas, E.5
Battegay, E.J.6
-
164
-
-
0034608894
-
Tumor necrosis factor a mediates apoptosis of brown adipocytes and defective brown adipocyte function in obesity
-
Nisoli E, Briscini L, Giordano A, Tonello C, Wiesbrock SM, Uysal KT, Cinti S, Carruba MO, Hotamisligil GS. Tumor necrosis factor a mediates apoptosis of brown adipocytes and defective brown adipocyte function in obesity. Proc Natl Acad Sci USA. 2000; 97(14):8033-8038.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.14
, pp. 8033-8038
-
-
Nisoli, E.1
Briscini, L.2
Giordano, A.3
Tonello, C.4
Wiesbrock, S.M.5
Uysal, K.T.6
Cinti, S.7
Carruba, M.O.8
Hotamisligil, G.S.9
-
165
-
-
33749442351
-
TNF-α downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents
-
Valerio A, Cardile A, Cozzi V, Bracale R, Tedesco L, Pisconti A, Palomba L, Cantoni O, Clementi E, Moncada S, Carruba MO, Nisoli E. TNF-α downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents. J Clin Invest. 2006;116(10):2791-2798.
-
(2006)
J Clin Invest
, vol.116
, Issue.10
, pp. 2791-2798
-
-
Valerio, A.1
Cardile, A.2
Cozzi, V.3
Bracale, R.4
Tedesco, L.5
Pisconti, A.6
Palomba, L.7
Cantoni, O.8
Clementi, E.9
Moncada, S.10
Carruba, M.O.11
Nisoli, E.12
-
166
-
-
84878650010
-
Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes
-
Sakamoto T, TakahashiN, SawaragiY, Naknukool S, Yu R, Goto T, Kawada T. Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes. Am J Physiol Cell Physiol. 2013;304(8):C729-C738.
-
(2013)
Am J Physiol Cell Physiol
, vol.304
, Issue.8
, pp. C729-C738
-
-
Sakamoto, T.1
Takahashi, N.2
Sawaragi, Y.3
Naknukool, S.4
Yu, R.5
Goto, T.6
Kawada, T.7
-
167
-
-
84925857018
-
White-to-brown metabolic conversion of human adipocytes by JAK inhibition
-
Moisan A, Lee Y-K, Zhang JD, Hudak CS, Meyer CA, Prummer M, Zoffmann S, Truong HH, Ebeling M, Kiialainen A, Gérard R, Xia F, Schinzel RT, Amrein KE, Cowan CA. White-to-brown metabolic conversion of human adipocytes by JAK inhibition. Nat Cell Biol. 2014;17(1):57-67.
-
(2014)
Nat Cell Biol
, vol.17
, Issue.1
, pp. 57-67
-
-
Moisan, A.1
Lee, Y.-K.2
Zhang, J.D.3
Hudak, C.S.4
Meyer, C.A.5
Prummer, M.6
Zoffmann, S.7
Truong, H.H.8
Ebeling, M.9
Kiialainen, A.10
Gérard, R.11
Xia, F.12
Schinzel, R.T.13
Amrein, K.E.14
Cowan, C.A.15
-
168
-
-
84899124414
-
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
-
Mauer J, Chaurasia B, Goldau J, Vogt MC, Ruud J, Nguyen KD, Theurich S, Hausen AC, Schmitz J, Brö nnekeHS, Estevez E, Allen TL, Mesaros A, Partridge L, FebbraioMA, Chawla A, Wunderlich FT, Brüning JC. Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nat Immunol. 2014;15(5):423-430.
-
(2014)
Nat Immunol
, vol.15
, Issue.5
, pp. 423-430
-
-
Mauer, J.1
Chaurasia, B.2
Goldau, J.3
Vogt, M.C.4
Ruud, J.5
Nguyen, K.D.6
Theurich, S.7
Hausen, A.C.8
Schmitz, J.9
Brönneke, H.S.10
Estevez, E.11
Allen, T.L.12
Mesaros, A.13
Partridge, L.14
Febbraio, M.A.15
Chawla, A.16
Wunderlich, F.T.17
Brüning, J.C.18
-
169
-
-
2542548063
-
Obesity and the metabolic syndrome in children and adolescents
-
Weiss R, Dziura J, Burgert TS, Tamborlane WV, Taksali SE, Yeckel CW, Allen K, Lopes M, Savoye M, Morrison J, Sherwin RS, Caprio S. Obesity and the metabolic syndrome in children and adolescents. N Engl J Med. 2004;350(23):2362-2374.
-
(2004)
N Engl J Med
, vol.350
, Issue.23
, pp. 2362-2374
-
-
Weiss, R.1
Dziura, J.2
Burgert, T.S.3
Tamborlane, W.V.4
Taksali, S.E.5
Yeckel, C.W.6
Allen, K.7
Lopes, M.8
Savoye, M.9
Morrison, J.10
Sherwin, R.S.11
Caprio, S.12
-
170
-
-
12144290761
-
Differential effects of interleukin-6 and-10 on skeletal muscle and liver insulin action in vivo
-
Kim H-J, Higashimori T, Park S-Y, Choi H, Dong J, Kim Y-J, Noh H-L, Cho Y-R, Cline G, Kim Y-B, Kim JK. Differential effects of interleukin-6 and-10 on skeletal muscle and liver insulin action in vivo. Diabetes. 2004;53(4):1060-1067.
-
(2004)
Diabetes
, vol.53
, Issue.4
, pp. 1060-1067
-
-
Kim, H.-J.1
Higashimori, T.2
Park, S.-Y.3
Choi, H.4
Dong, J.5
Kim, Y.-J.6
Noh, H.-L.7
Cho, Y.-R.8
Cline, G.9
Kim, Y.-B.10
Kim, J.K.11
-
171
-
-
0036152683
-
Interleukin-6-deficient mice develop mature-onset obesity
-
Wallenius V, Wallenius K, Ahrén B, Rudling M, Carlsten H, Dickson SL, Ohlsson C, Jansson J-O. Interleukin-6-deficient mice develop mature-onset obesity. Nat Med. 2002;8(1):75-79.
-
(2002)
Nat Med
, vol.8
, Issue.1
, pp. 75-79
-
-
Wallenius, V.1
Wallenius, K.2
Ahrén, B.3
Rudling, M.4
Carlsten, H.5
Dickson, S.L.6
Ohlsson, C.7
Jansson, J.-O.8
-
172
-
-
3042739678
-
Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity
-
Di Gregorio GB, Hensley L, Lu T, Ranganathan G, Kern PA. Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity.AmJ Physiol Endocrinol Metab. 2004;287(1):E182-E187.
-
(2004)
AmJ Physiol Endocrinol Metab
, vol.287
, Issue.1
, pp. E182-E187
-
-
Di Gregorio, G.B.1
Hensley, L.2
Lu, T.3
Ranganathan, G.4
Kern, P.A.5
-
173
-
-
33748466547
-
Reduced stress-and cold-induced increase in energy expenditure in interleukin-6-deficient mice
-
Wernstedt I, Edgley A, Berndtsson A, Fäldt J, Bergström G, Wallenius V, Jansson J-O. Reduced stress-and cold-induced increase in energy expenditure in interleukin-6-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2006;291(3):R551-R557.
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.291
, Issue.3
, pp. R551-R557
-
-
Wernstedt, I.1
Edgley, A.2
Berndtsson, A.3
Fäldt, J.4
Bergström, G.5
Wallenius, V.6
Jansson, J.-O.7
-
174
-
-
84943638331
-
Sympathetic nerve activity maintains an anti-inflammatory state in adipose tissue in male mice by inhibiting TNF-α gene expression in macrophages
-
Tang L, Okamoto S, Shiuchi T, Toda C, Takagi K, Sato T, Saito K, Yokota S, Minokoshi Y. Sympathetic nerve activity maintains an anti-inflammatory state in adipose tissue in male mice by inhibiting TNF-α gene expression in macrophages. Endocrinology. 2015;156(10):3680-3694.
-
(2015)
Endocrinology
, vol.156
, Issue.10
, pp. 3680-3694
-
-
Tang, L.1
Okamoto, S.2
Shiuchi, T.3
Toda, C.4
Takagi, K.5
Sato, T.6
Saito, K.7
Yokota, S.8
Minokoshi, Y.9
-
176
-
-
34748836407
-
Chemotaxis and differentiation of human adipose tissue CD34+/CD312 progenitor cells: role of stromal derived factor-1 released by adipose tissue capillary endothelial cells
-
Sengenès C, Miranville A, Maumus M, de Barros S, Busse R, Bouloumié A. Chemotaxis and differentiation of human adipose tissue CD34+/CD312 progenitor cells: role of stromal derived factor-1 released by adipose tissue capillary endothelial cells. Stem Cells. 2009;25(9):2269-2276.
-
(2009)
Stem Cells
, vol.25
, Issue.9
, pp. 2269-2276
-
-
Sengenès, C.1
Miranville, A.2
Maumus, M.3
de Barros, S.4
Busse, R.5
Bouloumié, A.6
-
177
-
-
33847258328
-
Constitutive and regulated expression and secretion of interferon-gamma-inducible protein 10 (IP-10/CXCL10) in human adipocytes
-
Herder C, Hauner H, Kempf K, Kolb H, Skurk T. Constitutive and regulated expression and secretion of interferon-gamma-inducible protein 10 (IP-10/CXCL10) in human adipocytes. Int J Obes. 2006;31(3):403-410.
-
(2006)
Int J Obes
, vol.31
, Issue.3
, pp. 403-410
-
-
Herder, C.1
Hauner, H.2
Kempf, K.3
Kolb, H.4
Skurk, T.5
-
178
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest. 2006;116(11):3015-3025.
-
(2006)
J Clin Invest
, vol.116
, Issue.11
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
179
-
-
0038143617
-
Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids
-
Lee JY, Plakidas A, Lee WH, Heikkinen A, Chanmugam P, Bray G, Hwang DH. Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. J Lipid Res. 2002;44(3):479-486.
-
(2002)
J Lipid Res
, vol.44
, Issue.3
, pp. 479-486
-
-
Lee, J.Y.1
Plakidas, A.2
Lee, W.H.3
Heikkinen, A.4
Chanmugam, P.5
Bray, G.6
Hwang, D.H.7
-
180
-
-
84916898719
-
Discovery of a class of endogenous mammalian lipids with antidiabetic and anti-inflammatory effects
-
Yore MM, Syed I, Moraes-Vieira PM, Zhang T, Herman MA, Homan EA, Patel RT, Lee J, Chen S, Peroni OD, Dhaneshwar AS, Hammarstedt A, Smith U, McGraw TE, Saghatelian A, Kahn BB. Discovery of a class of endogenous mammalian lipids with antidiabetic and anti-inflammatory effects. Cell. 2014;159(2): 318-332.
-
(2014)
Cell
, vol.159
, Issue.2
, pp. 318-332
-
-
Yore, M.M.1
Syed, I.2
Moraes-Vieira, P.M.3
Zhang, T.4
Herman, M.A.5
Homan, E.A.6
Patel, R.T.7
Lee, J.8
Chen, S.9
Peroni, O.D.10
Dhaneshwar, A.S.11
Hammarstedt, A.12
Smith, U.13
McGraw, T.E.14
Saghatelian, A.15
Kahn, B.B.16
-
181
-
-
51549107903
-
Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism
-
Cao H, Gerhold K, Mayers JR, Wiest MM, Watkins SM, Hotamisligil GS. Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism. Cell. 2008;134(6): 933-944.
-
(2008)
Cell
, vol.134
, Issue.6
, pp. 933-944
-
-
Cao, H.1
Gerhold, K.2
Mayers, J.R.3
Wiest, M.M.4
Watkins, S.M.5
Hotamisligil, G.S.6
-
182
-
-
84983523949
-
Docosahexaenoic acid-derived fatty acid esters of hydroxy fatty acids (FAHFAs) with anti-inflammatory properties
-
Kuda O, Brezinova M, Rombaldova M, Slavikova B, Posta M, Beier P, Janovska P, Veleba J, Kopecky J, Jr, Kudova E, Pelikanova T, Kopecky J. Docosahexaenoic acid-derived fatty acid esters of hydroxy fatty acids (FAHFAs) with anti-inflammatory properties. Diabetes. 2016;65(9):2580-2590.
-
(2016)
Diabetes
, vol.65
, Issue.9
, pp. 2580-2590
-
-
Kuda, O.1
Brezinova, M.2
Rombaldova, M.3
Slavikova, B.4
Posta, M.5
Beier, P.6
Janovska, P.7
Veleba, J.8
Kopecky, J.9
Kudova, E.10
Pelikanova, T.11
Kopecky, J.12
-
183
-
-
84873407575
-
Is there something special about palmitoleate?
-
Hodson L, Karpe F. Is there something special about palmitoleate? Curr Opin Clin Nutr Metab Care. 2013;16(2):225-231.
-
(2013)
Curr Opin Clin Nutr Metab Care
, vol.16
, Issue.2
, pp. 225-231
-
-
Hodson, L.1
Karpe, F.2
-
184
-
-
84875852161
-
Effects of adipocyte lipoprotein lipase on de novo lipogenesis and white adipose tissue browning
-
Bartelt A, Weigelt C, CherradiML, Niemeier A, Tö dter K, Heeren J, Scheja L. Effects of adipocyte lipoprotein lipase on de novo lipogenesis and white adipose tissue browning. Biochim Biophys Acta. 2013;1831:934-942.
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 934-942
-
-
Bartelt, A.1
Weigelt, C.2
Cherradi, M.L.3
Niemeier, A.4
Tödter, K.5
Heeren, J.6
Scheja, L.7
-
185
-
-
77956165390
-
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulinsensitizing effects
-
Oh DY, Talukdar S, Bae EJ, Imamura T, Morinaga H, Fan W, Li P, Lu WJ, Watkins SM, Olefsky JM. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulinsensitizing effects. Cell. 2010;142(5):687-698.
-
(2010)
Cell
, vol.142
, Issue.5
, pp. 687-698
-
-
Oh, D.Y.1
Talukdar, S.2
Bae, E.J.3
Imamura, T.4
Morinaga, H.5
Fan, W.6
Li, P.7
Lu, W.J.8
Watkins, S.M.9
Olefsky, J.M.10
-
186
-
-
84900554165
-
Brown andwhite adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice
-
Rosell M, Kaforou M, Frontini A, Okolo A, Chan Y-W, Nikolopoulou E, Millership S, Fenech ME, MacIntyre D, Turner JO, Moore JD, Blackburn E, Gullick WJ, Cinti S, Montana G, ParkerMG, ChristianM.Brown andwhite adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice. Am J Physiol Endocrinol Metab. 2014;306(8):E945-E964.
-
(2014)
Am J Physiol Endocrinol Metab
, vol.306
, Issue.8
, pp. E945-E964
-
-
Rosell, M.1
Kaforou, M.2
Frontini, A.3
Okolo, A.4
Chan, Y.-W.5
Nikolopoulou, E.6
Millership, S.7
Fenech, M.E.8
MacIntyre, D.9
Turner, J.O.10
Moore, J.D.11
Blackburn, E.12
Gullick, W.J.13
Cinti, S.14
Montana, G.15
Parker, M.G.16
Christian, M.17
-
187
-
-
84961956876
-
Relevance of lipid metabolism for brown fat visualization and quantification
-
Schilperoort M, Hoeke G, Kooijman S, Rensen PCN. Relevance of lipid metabolism for brown fat visualization and quantification. Curr Opin Lipidol. 2016;27(3):242-248.
-
(2016)
Curr Opin Lipidol
, vol.27
, Issue.3
, pp. 242-248
-
-
Schilperoort, M.1
Hoeke, G.2
Kooijman, S.3
Rensen, P.C.N.4
-
188
-
-
84875858745
-
White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma
-
Frontini A, Vitali A, Perugini J, Murano I, Romiti C, Ricquier D, Guerrieri M, Cinti S. White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma. Biochim Biophys Acta. 2013;1831:950-959.
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 950-959
-
-
Frontini, A.1
Vitali, A.2
Perugini, J.3
Murano, I.4
Romiti, C.5
Ricquier, D.6
Guerrieri, M.7
Cinti, S.8
-
189
-
-
84961290714
-
Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis
-
Sidossis L, Kajimura S. Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis. J Clin Invest. 2015;125(2):478-486.
-
(2015)
J Clin Invest
, vol.125
, Issue.2
, pp. 478-486
-
-
Sidossis, L.1
Kajimura, S.2
-
190
-
-
84940611205
-
A worm of one's own: how helminths modulate host adipose tissue function and metabolism
-
Guigas B, Molofsky AB. A worm of one's own: how helminths modulate host adipose tissue function and metabolism. Trends Parasitol. 2015;31(9):435-441.
-
(2015)
Trends Parasitol
, vol.31
, Issue.9
, pp. 435-441
-
-
Guigas, B.1
Molofsky, A.B.2
-
191
-
-
84872166765
-
Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis
-
Odegaard JI, Chawla A. Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis. Science. 2013; 339(6116):172-177.
-
(2013)
Science
, vol.339
, Issue.6116
, pp. 172-177
-
-
Odegaard, J.I.1
Chawla, A.2
-
192
-
-
0018646453
-
A role for brown adipose tissue in dietinduced thermogenesis
-
Rothwell NJ, Stock MJ. A role for brown adipose tissue in dietinduced thermogenesis. Nature. 1979;281(5726):31-35.
-
(1979)
Nature
, vol.281
, Issue.5726
, pp. 31-35
-
-
Rothwell, N.J.1
Stock, M.J.2
-
193
-
-
84960369640
-
Convertible visceral fat as a therapeutic target to curb obesity
-
Giordano A, Frontini A, Cinti S. Convertible visceral fat as a therapeutic target to curb obesity. Nat Rev Drug Discov. 2016; 15(6):405-424.
-
(2016)
Nat Rev Drug Discov
, vol.15
, Issue.6
, pp. 405-424
-
-
Giordano, A.1
Frontini, A.2
Cinti, S.3
-
194
-
-
79958244231
-
PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
-
Varga T, Czimmerer Z, Nagy L. PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation. Biochim Biophys Acta. 2011;1812: 1007-1022.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 1007-1022
-
-
Varga, T.1
Czimmerer, Z.2
Nagy, L.3
-
195
-
-
0023190209
-
The effects of various carbohydrates on sympathetic activity in heart and interscapular brown adipose tissue of the rat
-
Walgren MC, Young JB, Kaufman LN, Landsberg L. The effects of various carbohydrates on sympathetic activity in heart and interscapular brown adipose tissue of the rat. Metabolism. 1987; 36(6):585-594.
-
(1987)
Metabolism
, vol.36
, Issue.6
, pp. 585-594
-
-
Walgren, M.C.1
Young, J.B.2
Kaufman, L.N.3
Landsberg, L.4
|