Pharmacological and genetic manipulation of p53 in brown fat at adult but not embryonic stages regulates thermogenesis and body weight in male mice

Endocrinology

Volumn 157, Issue 7, 2016, Pages 2735-2749

  Al Massadi, Omar ^a,b   Porteiro, Begoña ^a,b   Kuhlow, Doreen ^c   Köhler, Markus ^c   Gonzalez Rellan, María J ^a,b   Garcia Lavandeira, Montserrat ^a   Díaz Rodríguez, Esther ^a   Quiñones, Mar ^a,b   Senra, Ana ^a   Alvarez, Clara V ^a   López, Miguel ^a,b   Diéguez, Carlos ^a,b   Schulz, Tim J ^c,d   Nogueiras, Rubén ^a,b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Instituto de Salud Carlos III   (Spain)

^c GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^d GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR; BETA ADRENORECEPTOR 3; CONTUSUGENE LADENOVEC; CRE RECOMBINASE; DOXORUBICIN; FAT DROPLET; FIBROBLAST GROWTH FACTOR 21; OSTEOGENIC PROTEIN 1; PRDM16 PROTEIN; PROTEIN; PROTEIN P53; PROTEIN RET; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; VIRUS VECTOR;

ADRENERGIC SYSTEM; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DIET INDUCED OBESITY; EMBRYO; ENERGY EXPENDITURE; FAT MASS; FETUS DEVELOPMENT; FOOD INTAKE; GAIN OF FUNCTION MUTATION; GENE OVEREXPRESSION; GENETIC MANIPULATION; GROWTH HORMONE SECRETING CELL; IMMUNOHISTOCHEMISTRY; INDIRECT CALORIMETRY; LOCOMOTION; LOSS OF FUNCTION MUTATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY QUOTIENT; SKELETAL MUSCLE; THERMOGENESIS; THERMOGRAPHY; UPREGULATION; WEIGHT GAIN; WESTERN BLOTTING; WILD TYPE; AGONISTS; ANIMAL; BODY COMPOSITION; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; OBESITY; RAT;

ADIPOSE TISSUE, BROWN; ANIMALS; BODY COMPOSITION; BODY WEIGHT; CELL LINE; DOXORUBICIN; MALE; MICE; MICE, KNOCKOUT; OBESITY; RATS; SOMATOTROPHS; THERMOGENESIS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84977139404     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2016-1209     Document Type: Article

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