-
1
-
-
0034611678
-
Towards a molecular understanding of adaptive thermogenesis
-
Lowell BB, Spiegelman BM 2000 Towards a molecular understanding of adaptive thermogenesis. Nature 404:652-660
-
(2000)
Nature
, vol.404
, pp. 652-660
-
-
Lowell, B.B.1
Spiegelman, B.M.2
-
2
-
-
0031771002
-
Brown adipose tissue. More than an effector of thermogenesis?
-
Cannon B, Houstek J, Nedergaard J 1998 Brown adipose tissue. More than an effector of thermogenesis? Ann NY Acad Sci 856:171-187
-
(1998)
Ann NY Acad Sci
, vol.856
, pp. 171-187
-
-
Cannon, B.1
Houstek, J.2
Nedergaard, J.3
-
3
-
-
0018646453
-
A role for brown adipose tissue in diet-induced thermogenesis
-
Rothwell NJ, Stock MJ 1979 A role for brown adipose tissue in diet-induced thermogenesis. Nature 281:31-35
-
(1979)
Nature
, vol.281
, pp. 31-35
-
-
Rothwell, N.J.1
Stock, M.J.2
-
4
-
-
1842409029
-
Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese
-
Enerback S, Jacobsson A, Simpson EM, Guerra C, Yamashita H, Harper ME, Kozak LP 1997 Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese. Nature 387:90-94
-
(1997)
Nature
, vol.387
, pp. 90-94
-
-
Enerback, S.1
Jacobsson, A.2
Simpson, E.M.3
Guerra, C.4
Yamashita, H.5
Harper, M.E.6
Kozak, L.P.7
-
6
-
-
0024695946
-
Molecular biology of brown adipose tissue
-
Ricquier D 1989 Molecular biology of brown adipose tissue. Proc Nutr Soc 48:183-187
-
(1989)
Proc Nutr Soc
, vol.48
, pp. 183-187
-
-
Ricquier, D.1
-
7
-
-
0029561581
-
Thyroid hormone control of thermogenesis and energy balance
-
Silva JE 1995 Thyroid hormone control of thermogenesis and energy balance. Thyroid 5:481-492
-
(1995)
Thyroid
, vol.5
, pp. 481-492
-
-
Silva, J.E.1
-
8
-
-
0033038403
-
Thyroid hormone and other regulators of uncoupling proteins
-
Reitman ML, He Y, Gong DW 1999 Thyroid hormone and other regulators of uncoupling proteins. Int J Obes Relat Metab Disord 23(Suppl 6):S56-S59
-
(1999)
Int J Obes Relat Metab Disord
, vol.23
, Issue.SUPPL. 6
-
-
Reitman, M.L.1
He, Y.2
Gong, D.W.3
-
9
-
-
0025047553
-
Skeletal muscle metabolism is a major determinant of resting energy expenditure
-
Zurlo F, Larson K, Bogardus C, Ravussin E 1990 Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest 86:1423-1427
-
(1990)
J Clin Invest
, vol.86
, pp. 1423-1427
-
-
Zurlo, F.1
Larson, K.2
Bogardus, C.3
Ravussin, E.4
-
10
-
-
0028196939
-
Whole-body energy metabolism and skeletal muscle biochemical characteristics
-
Zurlo F, Nemeth PM, Choksi RM, Sesodia S, Ravussin E 1994 Whole-body energy metabolism and skeletal muscle biochemical characteristics. Metabolism 43:481-486
-
(1994)
Metabolism
, vol.43
, pp. 481-486
-
-
Zurlo, F.1
Nemeth, P.M.2
Choksi, R.M.3
Sesodia, S.4
Ravussin, E.5
-
11
-
-
0026443844
-
Thermogenic response to epinephrine in the forearm and abdominal subcutaneous adipose tissue
-
Simonsen L, Bulow J, Madsen J, Christensen NJ 1992 Thermogenic response to epinephrine in the forearm and abdominal subcutaneous adipose tissue. Am J Physiol 263:E850-E855
-
(1992)
Am J Physiol
, vol.263
-
-
Simonsen, L.1
Bulow, J.2
Madsen, J.3
Christensen, N.J.4
-
12
-
-
0031019249
-
Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinemia
-
Fleury C, Neverova M, Collins S, Raimbault S, Champigny O, Levi-Meyrueis C, Bouillaud F, Seldin MF, Surwit RS, Ricquier, D, Warden, CH 1997 Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat Genet 15:269-272
-
(1997)
Nat Genet
, vol.15
, pp. 269-272
-
-
Fleury, C.1
Neverova, M.2
Collins, S.3
Raimbault, S.4
Champigny, O.5
Levi-Meyrueis, C.6
Bouillaud, F.7
Seldin, M.F.8
Surwit, R.S.9
Ricquier, D.10
Warden, C.H.11
-
13
-
-
15144356206
-
Cloning and characterization of an uncoupling protein homolog: A potential molecular mediator of human thermogenesis
-
Gimeno RE, Dembski M, Weng X, Deng N, Shyjan AW, Gimeno CJ, Iris F, Ellis SJ, Woolf EA, Tartaglia LA 1997 Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis. Diabetes 46:900-906
-
(1997)
Diabetes
, vol.46
, pp. 900-906
-
-
Gimeno, R.E.1
Dembski, M.2
Weng, X.3
Deng, N.4
Shyjan, A.W.5
Gimeno, C.J.6
Iris, F.7
Ellis, S.J.8
Woolf, E.A.9
Tartaglia, L.A.10
-
14
-
-
0030988140
-
Uncoupling protein-3: A new member of the mitochondrial carrier family with tissue-specific expression
-
Boss O, Samec S, Paoloni-Giacobino A, Rosier C, Dulloo A, Seydoux J, Muzzin P, Giacobino JP 1997 Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett 408:39-42
-
(1997)
FEBS Lett
, vol.408
, pp. 39-42
-
-
Boss, O.1
Samec, S.2
Paoloni-Giacobino, A.3
Rosier, C.4
Dulloo, A.5
Seydoux, J.6
Muzzin, P.7
Giacobino, J.P.8
-
15
-
-
0030869755
-
Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin
-
Gong DW, He Y, Karas M, Reitman M 1997 Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin. J Biol Chem 272:24129-24132
-
(1997)
J Biol Chem
, vol.272
, pp. 24129-24132
-
-
Gong, D.W.1
He, Y.2
Karas, M.3
Reitman, M.4
-
16
-
-
0031560941
-
UCP3: An uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue
-
Vidal-Puig A, Solanes G, Grujic D, Flier JS, Lowell BB 1997 UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue. Biochem Biophys Res Commun 235:79-82
-
(1997)
Biochem Biophys Res Commun
, vol.235
, pp. 79-82
-
-
Vidal-Puig, A.1
Solanes, G.2
Grujic, D.3
Flier, J.S.4
Lowell, B.B.5
-
17
-
-
0034717015
-
Energy metabolism in uncoupling protein 3 gene knockout mice
-
Vidal-Puig AJ, Grujic D, Zhang CY, Hagen T, Boss O, Ido Y, Szczepanik A, Wade J, Mootha V, Cortright R, Muoio DM, Lowell BB 2000 Energy metabolism in uncoupling protein 3 gene knockout mice. J Biol Chem 275:16258-16266
-
(2000)
J Biol Chem
, vol.275
, pp. 16258-16266
-
-
Vidal-Puig, A.J.1
Grujic, D.2
Zhang, C.Y.3
Hagen, T.4
Boss, O.5
Ido, Y.6
Szczepanik, A.7
Wade, J.8
Mootha, V.9
Cortright, R.10
Muoio, D.M.11
Lowell, B.B.12
-
18
-
-
0033667705
-
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
-
Arsenijevic D, Onuma H, Pecqueur C, Raimbault S, Manning BS, Miroux B, Couplan E, Alves-Guerra MC, Goubern M, Surwit R, Bouillaud F, Richard D, Collins S, Ricquier D 2000 Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet 26:435-439
-
(2000)
Nat Genet
, vol.26
, pp. 435-439
-
-
Arsenijevic, D.1
Onuma, H.2
Pecqueur, C.3
Raimbault, S.4
Manning, B.S.5
Miroux, B.6
Couplan, E.7
Alves-Guerra, M.C.8
Goubern, M.9
Surwit, R.10
Bouillaud, F.11
Richard, D.12
Collins, S.13
Ricquier, D.14
-
19
-
-
0035875087
-
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β cell dysfunction, and type 2 diabetes
-
Zhang CY, Baffy G, Perret P, Krauss S, Peroni O, Grujic D, Hagen T, Vidal-Puig AJ, Boss O, Kim YB, Zheng XX, Wheeler MB, Shulman GI, Chan CB, Lowell BB 2001 Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β cell dysfunction, and type 2 diabetes. Cell 105:745-755
-
(2001)
Cell
, vol.105
, pp. 745-755
-
-
Zhang, C.Y.1
Baffy, G.2
Perret, P.3
Krauss, S.4
Peroni, O.5
Grujic, D.6
Hagen, T.7
Vidal-Puig, A.J.8
Boss, O.9
Kim, Y.B.10
Zheng, X.X.11
Wheeler, M.B.12
Shulman, G.I.13
Chan, C.B.14
Lowell, B.B.15
-
20
-
-
0027300035
-
Tissue-specific and beta-adrenergic regulation of the mitochondrial uncoupling protein gene: Control by cis-acting elements in the 5′-flanking region
-
Cassard-Doulcier AM, Gelly C, Fox N, Schrementi J, Raimbault S, Klaus S, Forest C, Bouillaud F, Ricquier D 1993 Tissue-specific and beta-adrenergic regulation of the mitochondrial uncoupling protein gene: control by cis-acting elements in the 5′-flanking region. Mol Endocrinol 7:497-506
-
(1993)
Mol Endocrinol
, vol.7
, pp. 497-506
-
-
Cassard-Doulcier, A.M.1
Gelly, C.2
Fox, N.3
Schrementi, J.4
Raimbault, S.5
Klaus, S.6
Forest, C.7
Bouillaud, F.8
Ricquier, D.9
-
21
-
-
0028153698
-
An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene
-
Kozak UC, Kopecky J, Teisinger J, Enerback S, Boyer B, Kozak LP 1994 An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene. Mol Cell Biol 14:59-67
-
(1994)
Mol Cell Biol
, vol.14
, pp. 59-67
-
-
Kozak, U.C.1
Kopecky, J.2
Teisinger, J.3
Enerback, S.4
Boyer, B.5
Kozak, L.P.6
-
22
-
-
0027938708
-
In vitro interactions between nuclear proteins and uncoupling protein gene promoter reveal several putative transactivating factors including Ets1, retinoid X receptor, thyroid hormone receptor, and a CACCC box-binding protein
-
Cassard-Doulcier AM, Larose M, Matamala JC, Champigny O, Bouillaud F, Ricquier D 1994 In vitro interactions between nuclear proteins and uncoupling protein gene promoter reveal several putative transactivating factors including Ets1, retinoid X receptor, thyroid hormone receptor, and a CACCC box-binding protein. J Biol Chem 269:24335-24342
-
(1994)
J Biol Chem
, vol.269
, pp. 24335-24342
-
-
Cassard-Doulcier, A.M.1
Larose, M.2
Matamala, J.C.3
Champigny, O.4
Bouillaud, F.5
Ricquier, D.6
-
23
-
-
0035847001
-
Peroxisome proliferator-activated receptor α activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell
-
Barbera MJ, Schluter A, Pedraza N, Iglesias R, Villarroya F, Giralt M 2001 Peroxisome proliferator-activated receptor α activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell. J Biol Chem 276:1486-1493
-
(2001)
J Biol Chem
, vol.276
, pp. 1486-1493
-
-
Barbera, M.J.1
Schluter, A.2
Pedraza, N.3
Iglesias, R.4
Villarroya, F.5
Giralt, M.6
-
24
-
-
0029941669
-
Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: Regulation by peroxisome proliferator-activated receptor γ
-
Sears IB, MacGinnitie MA, Kovacs LG, Graves RA 1996 Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: regulation by peroxisome proliferator-activated receptor γ. Mol Cell Biol 16:3410-3419
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3410-3419
-
-
Sears, I.B.1
MacGinnitie, M.A.2
Kovacs, L.G.3
Graves, R.A.4
-
25
-
-
0030582447
-
Induction of uncoupling protein in brown adipose tissue. Synergy between norepinephrine and pioglitazone, an insulin-sensitizing agent
-
Foellmi-Adams LA, Wyse BM, Herron D, Nedergaard J, Kletzien RF 1996 Induction of uncoupling protein in brown adipose tissue. Synergy between norepinephrine and pioglitazone, an insulin-sensitizing agent. Biochem Pharmacol 52:693-701
-
(1996)
Biochem Pharmacol
, vol.52
, pp. 693-701
-
-
Foellmi-Adams, L.A.1
Wyse, B.M.2
Herron, D.3
Nedergaard, J.4
Kletzien, R.F.5
-
26
-
-
10544229796
-
Activation of the nuclear receptor peroxisome proliferator-activated receptor γ promotes brown adipocyte differentiation
-
Tai TA, Jennermann C, Brown KK, Oliver BB, MacGinnitie MA, Wilkison WO, Brown HR, Lehmann JM, Kliewer SA, Morris DC, Graves RA 1996 Activation of the nuclear receptor peroxisome proliferator-activated receptor γ promotes brown adipocyte differentiation. J Biol Chem 271:29909-29914
-
(1996)
J Biol Chem
, vol.271
, pp. 29909-29914
-
-
Tai, T.A.1
Jennermann, C.2
Brown, K.K.3
Oliver, B.B.4
MacGinnitie, M.A.5
Wilkison, W.O.6
Brown, H.R.7
Lehmann, J.M.8
Kliewer, S.A.9
Morris, D.C.10
Graves, R.A.11
-
27
-
-
0033213637
-
PPAR γ is required for placental, cardiac, and adipose tissue development
-
Barak Y, Nelson MC, Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR, Koder A, Evans RM 1999 PPAR γ is required for placental, cardiac, and adipose tissue development. Mol Cell 4:585-595
-
(1999)
Mol Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Jones, Y.Z.4
Ruiz-Lozano, P.5
Chien, K.R.6
Koder, A.7
Evans, R.M.8
-
28
-
-
0033213631
-
PPAR γ is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen ED, Sarraf P, Troy AE, Bradwin G, Moore K, Milstone DS, Spiegelman BM, Mortensen RM 1999 PPAR γ is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell 4:611-617
-
(1999)
Mol Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
Bradwin, G.4
Moore, K.5
Milstone, D.S.6
Spiegelman, B.M.7
Mortensen, R.M.8
-
29
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM 1998 A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92:829-839
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
30
-
-
0033546748
-
Role of the β(3)-adrenergic receptor and/or a putative β(4)-adrenergic receptor on the expression of uncoupling proteins and peroxisome proliferator-activated receptor-γ coactivator-1
-
Boss O, Bachman E, Vidal-Puig A, Zhang CY, Peroni O, Lowell BB 1999 Role of the β(3)-adrenergic receptor and/or a putative β(4)-adrenergic receptor on the expression of uncoupling proteins and peroxisome proliferator-activated receptor-γ coactivator-1. Biochem Biophys Res Commun 261:870-876
-
(1999)
Biochem Biophys Res Commun
, vol.261
, pp. 870-876
-
-
Boss, O.1
Bachman, E.2
Vidal-Puig, A.3
Zhang, C.Y.4
Peroni, O.5
Lowell, B.B.6
-
31
-
-
0343431408
-
Rapid in vivo PGC-1 mRNA upregulation in brown adipose tissue of Wistar rats by a β(3)-adrenergic agonist and lack of effect of leptin
-
Gomez-Ambrosi J, Fruhbeck G, Martinez JA 2001 Rapid in vivo PGC-1 mRNA upregulation in brown adipose tissue of Wistar rats by a β(3)-adrenergic agonist and lack of effect of leptin. Mol Cell Endocrinol 176:85-90
-
(2001)
Mol Cell Endocrinol
, vol.176
, pp. 85-90
-
-
Gomez-Ambrosi, J.1
Fruhbeck, G.2
Martinez, J.A.3
-
32
-
-
0037127204
-
Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β), a novel PGC-1-related transcription coactivator associated with host cell factor
-
Lin J, Puigserver P, Donovan J, Tarr P, Spiegelman BM 2002 Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β), a novel PGC-1-related transcription coactivator associated with host cell factor. J Biol Chem 277:1645-1648
-
(2002)
J Biol Chem
, vol.277
, pp. 1645-1648
-
-
Lin, J.1
Puigserver, P.2
Donovan, J.3
Tarr, P.4
Spiegelman, B.M.5
-
33
-
-
0034533378
-
Genetic studies of brown adipocyte induction
-
Kozak LP 2000 Genetic studies of brown adipocyte induction. J Nutr 130:3132S-3133S
-
(2000)
J Nutr
, vol.130
-
-
Kozak, L.P.1
-
34
-
-
0025346276
-
Thyroid hormone regulation of mitochondrial function. Comments on the mechanism of signal transduction
-
Nelson BD 1990 Thyroid hormone regulation of mitochondrial function. Comments on the mechanism of signal transduction. Biochim Biophys Acta 1018:275-277
-
(1990)
Biochim Biophys Acta
, vol.1018
, pp. 275-277
-
-
Nelson, B.D.1
-
35
-
-
0025313512
-
NRF-1: A trans-activator of nuclear-encoded respiratory genes in animal cells
-
Evans MJ, Scarpulla RC 1990 NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells. Genes Dev 4:1023-1034
-
(1990)
Genes Dev
, vol.4
, pp. 1023-1034
-
-
Evans, M.J.1
Scarpulla, R.C.2
-
36
-
-
0027256435
-
Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promoters
-
Virbasius JV, Virbasius CA, Scarpulla RC 1993 Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promoters. Genes Dev 7:380-392
-
(1993)
Genes Dev
, vol.7
, pp. 380-392
-
-
Virbasius, J.V.1
Virbasius, C.A.2
Scarpulla, R.C.3
-
37
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell BB, Scarpulla RC, Spiegelman BM 1999 Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98:115-124
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
Troy, A.7
Cinti, S.8
Lowell, B.B.9
Scarpulla, R.C.10
Spiegelman, B.M.11
-
38
-
-
0034770191
-
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1
-
Tsukiyama-Kohara K, Poulin F, Kohara M, DeMaria CT, Cheng A, Wu Z, Gingras AC, Katsume A, Elchebly M, Spiegelman BM, Harper ME, Tremblay ML, Sonenberg N 2001 Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1. Nat Med 7:1128-1132
-
(2001)
Nat Med
, vol.7
, pp. 1128-1132
-
-
Tsukiyama-Kohara, K.1
Poulin, F.2
Kohara, M.3
DeMaria, C.T.4
Cheng, A.5
Wu, Z.6
Gingras, A.C.7
Katsume, A.8
Elchebly, M.9
Spiegelman, B.M.10
Harper, M.E.11
Tremblay, M.L.12
Sonenberg, N.13
-
39
-
-
17944377509
-
FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance
-
Cederberg A, Gronning LM, Ahren B, Tasken K, Carlsson P, Enerback S 2001 FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance. Cell 106:563-573
-
(2001)
Cell
, vol.106
, pp. 563-573
-
-
Cederberg, A.1
Gronning, L.M.2
Ahren, B.3
Tasken, K.4
Carlsson, P.5
Enerback, S.6
-
40
-
-
0023491364
-
Anti-cachectin/TNF monoclonal anti-bodies prevent septic shock during lethal bacteraemia
-
Tracey KJ, Fong Y, Hesse DG, Manogue KR, Lee AT, Kuo GC, Lowry SF, Cerami A 1987 Anti-cachectin/TNF monoclonal anti-bodies prevent septic shock during lethal bacteraemia. Nature 330:662-664
-
(1987)
Nature
, vol.330
, pp. 662-664
-
-
Tracey, K.J.1
Fong, Y.2
Hesse, D.G.3
Manogue, K.R.4
Lee, A.T.5
Kuo, G.C.6
Lowry, S.F.7
Cerami, A.8
-
41
-
-
0027420579
-
Tumor necrosis factor: An updated review of its biology
-
Tracey KJ, Cerami A 1993 Tumor necrosis factor: an updated review of its biology. Crit Care Med 21:S415-422
-
(1993)
Crit Care Med
, vol.21
-
-
Tracey, K.J.1
Cerami, A.2
-
43
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ 2000 Signal transduction by the JNK group of MAP kinases. Cell 103:239-252
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
44
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang L, Karin M 2001 Mammalian MAP kinase signalling cascades. Nature 410:37-40
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
45
-
-
18244399631
-
Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARγ coactivator-1
-
Puigserver P, Rhee J, Lin J, Wu Z, Yoon JC, Zhang CY, Krauss S, Mootha VK, Lowell BB, Spiegelman BM 2001 Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARγ coactivator-1. Mol Cell 8:971-982
-
(2001)
Mol Cell
, vol.8
, pp. 971-982
-
-
Puigserver, P.1
Rhee, J.2
Lin, J.3
Wu, Z.4
Yoon, J.C.5
Zhang, C.Y.6
Krauss, S.7
Mootha, V.K.8
Lowell, B.B.9
Spiegelman, B.M.10
-
46
-
-
0033803048
-
Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis
-
Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP 2000 Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest 106:847-856
-
(2000)
J Clin Invest
, vol.106
, pp. 847-856
-
-
Lehman, J.J.1
Barger, P.M.2
Kovacs, A.3
Saffitz, J.E.4
Medeiros, D.M.5
Kelly, D.P.6
-
47
-
-
0030923761
-
A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program
-
Sack MN, Disch DL, Rockman HA, Kelly DP 1997 A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc Natl Acad Sci USA 94:6438-6443
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6438-6443
-
-
Sack, M.N.1
Disch, D.L.2
Rockman, H.A.3
Kelly, D.P.4
-
48
-
-
0033977890
-
The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor α in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
-
Vega RB, Huss JM, Kelly DP 2000 The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor α in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Mol Cell Biol 20:1868-1876
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1868-1876
-
-
Vega, R.B.1
Huss, J.M.2
Kelly, D.P.3
-
49
-
-
0028343190
-
Glucose fatty acid interactions and the regulation of glucose disposal
-
Randle PJ, Priestman DA, Mistry SC, Halsall A 1994 Glucose fatty acid interactions and the regulation of glucose disposal. J Cell Biochem 55(Suppl):1-11
-
(1994)
J Cell Biochem
, vol.55
, Issue.SUPPL.
, pp. 1-11
-
-
Randle, P.J.1
Priestman, D.A.2
Mistry, S.C.3
Halsall, A.4
-
50
-
-
0035957375
-
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
-
Michael LF, Wu Z, Cheatham RB, Puigserver P, Adelmant G, Lehman JJ, Kelly DP and Spiegelman BM 2001 Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proc Natl Acad Sci USA 98:3820-3825
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3820-3825
-
-
Michael, L.F.1
Wu, Z.2
Cheatham, R.B.3
Puigserver, P.4
Adelmant, G.5
Lehman, J.J.6
Kelly, D.P.7
Spiegelman, B.M.8
-
51
-
-
0035855858
-
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
-
Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman BM 2001 Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413:131-138
-
(2001)
Nature
, vol.413
, pp. 131-138
-
-
Yoon, J.C.1
Puigserver, P.2
Chen, G.3
Donovan, J.4
Wu, Z.5
Rhee, J.6
Adelmant, G.7
Stafford, J.8
Kahn, C.R.9
Granner, D.K.10
Newgard, C.B.11
Spiegelman, B.M.12
-
52
-
-
0035855905
-
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
-
Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman BM, Montminy M 2001 CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 413:179-183
-
(2001)
Nature
, vol.413
, pp. 179-183
-
-
Herzig, S.1
Long, F.2
Jhala, U.S.3
Hedrick, S.4
Quinn, R.5
Bauer, A.6
Rudolph, D.7
Schutz, G.8
Yoon, C.9
Puigserver, P.10
Spiegelman, B.M.11
Montminy, M.12
-
53
-
-
0035185021
-
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
-
Nakae J, Kitamura T, Silver DL, Accili D 2001 The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J Clin Invest 108:1359-1367
-
(2001)
J Clin Invest
, vol.108
, pp. 1359-1367
-
-
Nakae, J.1
Kitamura, T.2
Silver, D.L.3
Accili, D.4
-
54
-
-
0035368548
-
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB β)
-
Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EB, Kaestner KH, Bartolomei MS, Shulman GI, Birnbaum MJ 2001 Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB β). Science 292:1728-1731
-
(2001)
Science
, vol.292
, pp. 1728-1731
-
-
Cho, H.1
Mu, J.2
Kim, J.K.3
Thorvaldsen, J.L.4
Chu, Q.5
Crenshaw, E.B.6
Kaestner, K.H.7
Bartolomei, M.S.8
Shulman, G.I.9
Birnbaum, M.J.10
-
55
-
-
0037134493
-
The PGC-1-related protein PERC is a selective coactivator of estrogen receptor α
-
Kressler D, Schreiber SN, Knutti D, Kralli A 2002 The PGC-1-related protein PERC is a selective coactivator of estrogen receptor α. J Biol Chem 277:13918-13925
-
(2002)
J Biol Chem
, vol.277
, pp. 13918-13925
-
-
Kressler, D.1
Schreiber, S.N.2
Knutti, D.3
Kralli, A.4
-
56
-
-
0035016566
-
Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells
-
Andersson U, Scarpulla RC 2001 Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. Mol Cell Biol 21:3738-3749
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3738-3749
-
-
Andersson, U.1
Scarpulla, R.C.2
-
57
-
-
0030986236
-
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
-
Heery DM, Kalkhoven E, Hoare S, Parker MG 1997 A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 387:733-736
-
(1997)
Nature
, vol.387
, pp. 733-736
-
-
Heery, D.M.1
Kalkhoven, E.2
Hoare, S.3
Parker, M.G.4
-
58
-
-
0033513582
-
Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: Discovery of peptide antagonists of estrogen receptors alpha and beta
-
Chang C, Norris JD, Gron H, Paige LA, Hamilton PT, Kenan DJ, Fowlkes D, McDonnell DP 1999 Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta. Mol Cell Biol 19:8226-8239
-
(1999)
Mol Cell Biol
, vol.19
, pp. 8226-8239
-
-
Chang, C.1
Norris, J.D.2
Gron, H.3
Paige, L.A.4
Hamilton, P.T.5
Kenan, D.J.6
Fowlkes, D.7
McDonnell, D.P.8
-
59
-
-
0034717075
-
Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1
-
Tcherepanova I, Puigserver P, Norris JD, Spiegelman BM, McDonnell DP 2000 Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. J Biol Chem 275:16302-16308
-
(2000)
J Biol Chem
, vol.275
, pp. 16302-16308
-
-
Tcherepanova, I.1
Puigserver, P.2
Norris, J.D.3
Spiegelman, B.M.4
McDonnell, D.P.5
-
60
-
-
0037040253
-
PGC-1 functions as a transcriptional coactivator for the retinoid X receptors
-
Delerive P, Wu Y, Burris TP, Chin WW, Suen CS 2001 PGC-1 functions as a transcriptional coactivator for the retinoid X receptors. J Biol Chem 277:3913-3917
-
(2001)
J Biol Chem
, vol.277
, pp. 3913-3917
-
-
Delerive, P.1
Wu, Y.2
Burris, T.P.3
Chin, W.W.4
Suen, C.S.5
-
61
-
-
0034116143
-
A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen
-
Knutti D, Kaul A, Kralli A 2000 A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen. Mol Cell Biol 20:2411-2422
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2411-2422
-
-
Knutti, D.1
Kaul, A.2
Kralli, A.3
-
62
-
-
0028180070
-
mPPAR γ 2: Tissue-specific regulator of an adipocyte enhancer
-
Tontonoz P, Hu E, Graves RA, Budavari AI, Spiegelman BM 1994 mPPAR γ 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev 8:1224-1234
-
(1994)
Genes Dev
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
63
-
-
0033637703
-
Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
-
Shang Y, Hu X, DiRenzo J, Lazar MA, Brown M 2000 Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103:843-852
-
(2000)
Cell
, vol.103
, pp. 843-852
-
-
Shang, Y.1
Hu, X.2
DiRenzo, J.3
Lazar, M.A.4
Brown, M.5
-
64
-
-
0032030770
-
Histone acetylation and transcriptional regulatory mechanisms
-
Struhl K 1998 Histone acetylation and transcriptional regulatory mechanisms. Genes Dev 12:599-606
-
(1998)
Genes Dev
, vol.12
, pp. 599-606
-
-
Struhl, K.1
-
65
-
-
0034650893
-
The coregulator exchange in transcriptional functions of nuclear receptors
-
Glass CK, Rosenfeld MG 2000 The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev 14:121-141
-
(2000)
Genes Dev
, vol.14
, pp. 121-141
-
-
Glass, C.K.1
Rosenfeld, M.G.2
-
67
-
-
0032589689
-
Activation of PPARγ coactivator-1 through transcription factor docking
-
Puigserver P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman BM 1999 Activation of PPARγ coactivator-1 through transcription factor docking. Science 286:1368-1371
-
(1999)
Science
, vol.286
, pp. 1368-1371
-
-
Puigserver, P.1
Adelmant, G.2
Wu, Z.3
Fan, M.4
Xu, J.5
O'Malley, B.6
Spiegelman, B.M.7
-
68
-
-
0031466322
-
Transcription units as RNA processing units
-
Neugebauer KM, Roth MB 1997 Transcription units as RNA processing units. Genes Dev 11:3279-3285
-
(1997)
Genes Dev
, vol.11
, pp. 3279-3285
-
-
Neugebauer, K.M.1
Roth, M.B.2
-
69
-
-
0030670094
-
A CTD function linking transcription to splicing
-
Corden JL, Patturajan M 1997 A CTD function linking transcription to splicing. Trends Biochem Sci 22:413-416
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 413-416
-
-
Corden, J.L.1
Patturajan, M.2
-
70
-
-
0029959435
-
The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins
-
Yuryev A, Patturajan M, Litingtung Y, Joshi RV, Gentile C, Gebara M, Corden JL 1996 The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins. Proc Natl Acad Sci USA 93:6975-6980
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6975-6980
-
-
Yuryev, A.1
Patturajan, M.2
Litingtung, Y.3
Joshi, R.V.4
Gentile, C.5
Gebara, M.6
Corden, J.L.7
-
71
-
-
0033638283
-
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
-
Monsalve M, Wu Z, Adelmant G, Puigserver P, Fan M, Spiegelman BM 2000 Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol Cell 6:307-316
-
(2000)
Mol Cell
, vol.6
, pp. 307-316
-
-
Monsalve, M.1
Wu, Z.2
Adelmant, G.3
Puigserver, P.4
Fan, M.5
Spiegelman, B.M.6
-
72
-
-
0032483380
-
CBP: A signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV
-
Chawla S, Hardingham GE, Quinn DR, Bading H 1998 CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV. Science 281:1505-1509
-
(1998)
Science
, vol.281
, pp. 1505-1509
-
-
Chawla, S.1
Hardingham, G.E.2
Quinn, D.R.3
Bading, H.4
-
73
-
-
0034460313
-
8-Bromocyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein
-
Rowan BG, Garrison N, Weigel NL, O'Malley BW 2000 8-Bromocyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein. Mol Cell Biol 20:8720-8730
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8720-8730
-
-
Rowan, B.G.1
Garrison, N.2
Weigel, N.L.3
O'Malley, B.W.4
-
74
-
-
0035859836
-
Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor
-
Knutti D, Kressler D, Kralli A 2001 Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor. Proc Natl Acad Sci USA 98:9713-9718
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9713-9718
-
-
Knutti, D.1
Kressler, D.2
Kralli, A.3
-
75
-
-
0035977050
-
p38 Mitogen-activated protein kinase activates peroxisome proliferator-activated receptor α. A potential role in the cardia metabolic stress response
-
Barger PM, Browning AC, Garner AN, Kelly DP 2001 p38 Mitogen-activated protein kinase activates peroxisome proliferator-activated receptor α. A potential role in the cardia metabolic stress response. J Biol Chem 276:44495-44501
-
(2001)
J Biol Chem
, vol.276
, pp. 44495-44501
-
-
Barger, P.M.1
Browning, A.C.2
Garner, A.N.3
Kelly, D.P.4
-
76
-
-
0037198679
-
The TRAP220 subunit of the TRAP/mediator is required for PPARγ2-stimulated adipogenesis
-
Ge H, Guermah M, Yuan CX, Ito M, Walberg AE, Spiegelman BM, Roeder RG 2002 The TRAP220 subunit of the TRAP/mediator is required for PPARγ2-stimulated adipogenesis. Nature 417:563-567
-
(2002)
Nature
, vol.417
, pp. 563-567
-
-
Ge, H.1
Guermah, M.2
Yuan, C.X.3
Ito, M.4
Walberg, A.E.5
Spiegelman, B.M.6
Roeder, R.G.7
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