Deficiency in adipocyte chemokine receptor CXCR4 exacerbates obesity and compromises thermoregulatory responses of brown adipose tissue in a mouse model of diet-induced obesity

FASEB Journal

Volumn 28, Issue 10, 2014, Pages 4534-4550

  Yao, Longbiao ^a   Heuser Baker, Janet ^a   Herlea Pana, Oana ^a   Zhang, Nan ^a   Szweda, Luke I ^a   Griffin, Timothy M ^a   Barlic Dicen, Jana ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

Adaptive thermogenesis; Chemotactic cytokine system

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; INSULIN; RNA; UNCOUPLING PROTEIN 1; CXCR4 PROTEIN, MOUSE; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BROWN ADIPOSE TISSUE; CALORIMETRY; COLD TOLERANCE; CONTROLLED STUDY; DIETARY INTAKE; DISEASE EXACERBATION; ENERGY EXPENDITURE; ERYTHROCYTE COUNT; EXON; FEEDING; FOOD INTAKE; GENE EXPRESSION; GENOTYPE; GLUCOSE TOLERANCE TEST; IMMUNE DEFICIENCY; IMMUNOPHENOTYPING; INFLAMMATORY CELL; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; KNOCKOUT MOUSE; LEUKOCYTE COUNT; LIPID DIET; LYMPHOCYTE COUNT; METABOLIC RATE; MITOCHONDRIAL GENE; MOUSE; MOUSE MODEL; NEUTROPHIL COUNT; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA ANALYSIS; THERMOREGULATION; THROMBOCYTE COUNT; WHITE ADIPOSE TISSUE; WILD TYPE; ANIMAL; C57BL MOUSE; CYTOLOGY; GENETICS; LEUKOCYTE; METABOLISM; PHYSIOLOGY; THERMOGENESIS;

ADIPOCYTES; ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; ANIMALS; DIET, HIGH-FAT; ION CHANNELS; LEUKOCYTES; MICE; MICE, INBRED C57BL; MITOCHONDRIAL PROTEINS; OBESITY; RECEPTORS, CXCR4; THERMOGENESIS;

EID: 84907702213     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-249797     Document Type: Article

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