Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice

Nature Medicine

Volumn 22, Issue 3, 2016, Pages 312-318

  Min, So Yun ^a   Kady, Jamie ^a   Nam, Minwoo ^a   Rojas Rodriguez, Raziel ^a   Berkenwald, Aaron ^a   Kim, Jong Hun ^a   Noh, Hye Lim ^a   Kim, Jason K ^a   Cooper, Marcus P ^a   Fitzgibbons, Timothy ^a   Brehm, Michael A ^a   Corvera, Silvia ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ADIPONECTIN; ANGIOGENIC FACTOR; BETA1 INTEGRIN; CD24 ANTIGEN; FAT DROPLET; FATTY ACID BINDING PROTEIN 4; GLUCOSE TRANSPORTER 4; LEPTIN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; SERINE PROTEINASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 423; APOPTOSIS REGULATORY PROTEIN; CIDEA PROTEIN, HUMAN; DNA BINDING PROTEIN; ENKEPHALIN; GLUCOSE BLOOD LEVEL; IL33 PROTEIN, HUMAN; INTERLEUKIN 33; IODIDE PEROXIDASE; IODOTHYRONINE DEIODINASE TYPE II; ION CHANNEL; MESSENGER RNA; MITOCHONDRIAL PROTEIN; OAZ PROTEIN, HUMAN; PCSK1 PROTEIN, HUMAN; PROENKEPHALIN; PROPROTEIN CONVERTASE 1; PROTEIN PRECURSOR; UCP1 PROTEIN, HUMAN; UCP1 PROTEIN, MOUSE;

ADIPOCYTE; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEIGE ADIPOCYTE; BRITE ADIPOCYTE; CAPILLARY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL RESPIRATION; CONTROLLED STUDY; ENZYME ACTIVATION; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HOMEOSTASIS; HUMAN; HUMAN CELL; IMPLANTATION; IN VITRO STUDY; INTERSCAPULAR BROWN ADIPOSE TISSUE; LIPID DIET; METABOLIC DISORDER; MOUSE; NOD SCID GAMMA MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SECRETION; STEM CELL; WHITE ADIPOSE TISSUE; ADULT; AGED; ANIMAL; BROWN ADIPOCYTE; CELL TRANSPLANTATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; MALE; METABOLISM; MIDDLE AGED; OXYGEN CONSUMPTION; POLYMERASE CHAIN REACTION; TRANSPLANTATION; WHITE ADIPOCYTE;

ADIPOCYTES; ADIPOCYTES, BROWN; ADIPOCYTES, WHITE; ADULT; AGED; ANIMALS; ANTIGENS, CD29; APOPTOSIS REGULATORY PROTEINS; BLOOD GLUCOSE; CAPILLARIES; CELL TRANSPLANTATION; DIET, HIGH-FAT; DNA-BINDING PROTEINS; ENKEPHALINS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HOMEOSTASIS; HUMANS; INTERLEUKIN-33; IODIDE PEROXIDASE; ION CHANNELS; MALE; MICE; MIDDLE AGED; MITOCHONDRIAL PROTEINS; NEOVASCULARIZATION, PHYSIOLOGIC; OBESITY; OXYGEN CONSUMPTION; POLYMERASE CHAIN REACTION; PROPROTEIN CONVERTASE 1; PROTEIN PRECURSORS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RNA, MESSENGER; UNCOUPLING PROTEIN 1;

EID: 84955587698     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4031     Document Type: Article

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