Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue

EMBO Journal

Volumn 27, Issue 11, 2008, Pages 1537-1548

  Qi, Jingzong ^a   Gong, Jingyi ^a   Zhao, Tongjin ^a   Zhao, Jie ^a   Lam, Penny ^b   Ye, Jing ^a   Li, John Zhong ^b   Wu, Jiawei ^a   Zhou, Hai Meng ^a   Li, Peng ^a  

^a TSINGHUA UNIVERSITY   (China)

^b HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

AMPK; Brown adipose tissue; Cidea; Protein degradation; Ubiquitination

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; AMP ACTIVATED PROTEIN KINASES; AMP-ACTIVATED PROTEIN KINASES; APOPTOSIS REGULATORY PROTEIN; CIDEA PROTEIN, MOUSE; MULTIENZYME COMPLEX; PROTEIN SERINE THREONINE KINASE; PROTEIN SUBUNIT;

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BETA CHAIN; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; ENERGY EXPENDITURE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BLOOD LEVEL; ENZYME DEGRADATION; ENZYME LOCALIZATION; ENZYME REGULATION; ENZYME STABILITY; IN VIVO STUDY; MALE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; UBIQUITINATION; ADIPOCYTE; ANIMAL; CYTOLOGY; DOWN REGULATION; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE MUTANT; MUTATION;

MUS;

ADIPOCYTES; ADIPOSE TISSUE, BROWN; ANIMALS; APOPTOSIS REGULATORY PROTEINS; DOWN-REGULATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME STABILITY; MICE; MICE, KNOCKOUT; MULTIENZYME COMPLEXES; MUTATION; PROTEIN SUBUNITS; PROTEIN-SERINE-THREONINE KINASES; UBIQUITINATION;

EID: 44649099112     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.92     Document Type: Article

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