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Volumn 121, Issue 1, 2011, Pages 96-105

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

Author keywords

[No Author keywords available]

Indexed keywords

5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; GLUCOSE; PRDM16 PROTEIN; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 78650945931     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI44271     Document Type: Article
Times cited : (1022)

References (73)
  • 1
    • 60449094498 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2009 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Lloyd-Jones D, et al. Heart disease and stroke statistics - 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119(3):e21-181.
    • (2009) Circulation , vol.119 , Issue.3
    • Lloyd-Jones, D.1
  • 2
    • 0037036968 scopus 로고    scopus 로고
    • Diet and risk of coronary heart disease and type 2 diabetes
    • DOI 10.1016/S0140-6736(02)09901-4
    • Mann JI. Diet and risk of coronary heart disease and type 2 diabetes. Lancet. 2002;360(9335):783-789. (Pubitemid 35247712)
    • (2002) Lancet , vol.360 , Issue.9335 , pp. 783-789
    • Mann, J.I.1
  • 3
    • 15744387573 scopus 로고    scopus 로고
    • Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men
    • Wang Y, Rimm EB, Stampfer MJ, Willett WC, Hu FB. Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. Am J Clin Nutr. 2005;81(3):555-563.
    • (2005) Am J Clin Nutr , vol.81 , Issue.3 , pp. 555-563
    • Wang, Y.1    Rimm, E.B.2    Stampfer, M.J.3    Willett, W.C.4    Hu, F.B.5
  • 4
    • 34249883032 scopus 로고    scopus 로고
    • Waist circumference and cardiometabolic risk: A consensus statement from Shaping America's Health: Association for Weight Management and Obesity Prevention; NAASO, the Obesity Society; the American Society for Nutrition; and the American Diabetes Association
    • DOI 10.2337/dc07-9921
    • Klein S, et al. Waist circumference and cardiometabolic risk: a consensus statement from shaping America's health: Association for Weight Management and Obesity Prevention; NAASO, the Obesity Society; the American Society for Nutrition; and the American Diabetes Association. Diabetes Care. 2007;30(6):1647-1652. (Pubitemid 46871194)
    • (2007) Diabetes Care , vol.30 , Issue.6 , pp. 1647-1652
    • Klein, S.1    Allison, D.B.2    Heymsfield, S.B.3    Kelley, D.E.4    Leibel, R.L.5    Nonas, C.6    Kahn, R.7
  • 5
    • 34347351228 scopus 로고    scopus 로고
    • Abdominal visceral and subcutaneous adipose tissue compartments: Association with metabolic risk factors in the Framingham Heart Study
    • Fox CS, et al. Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation. 2007;116(1):39-48.
    • (2007) Circulation , vol.116 , Issue.1 , pp. 39-48
    • Fox, C.S.1
  • 6
    • 0029074972 scopus 로고
    • The insulin resistance-dyslipidemic syndrome: Contribution of visceral obesity and therapeutic implications
    • Despres JP, et al. The insulin resistance-dyslipidemic syndrome: contribution of visceral obesity and therapeutic implications. Int J Obes Relat Metab Disord. 1995;19 Suppl 1:S76-S86.
    • (1995) Int J Obes Relat Metab Disord , vol.19 , Issue.SUPPL. 1
    • Despres, J.P.1
  • 7
    • 0029856151 scopus 로고    scopus 로고
    • Separate associations between visceral and subcutaneous adipose tissue distribution, insulin and glucose levels in obese women
    • Ross R, Fortier L, Hudson R. Separate associations between visceral and subcutaneous adipose tissue distribution, insulin and glucose levels in obese women. Diabetes Care. 1996;19(12):1404-1411.
    • (1996) Diabetes Care , vol.19 , Issue.12 , pp. 1404-1411
    • Ross, R.1    Fortier, L.2    Hudson, R.3
  • 8
    • 0032477331 scopus 로고    scopus 로고
    • Abdominal adiposity and coronary heart disease in women
    • Rexrode KM, et al. Abdominal adiposity and coronary heart disease in women. JAMA. 1998;280(21):1843-1848.
    • (1998) JAMA , vol.280 , Issue.21 , pp. 1843-1848
    • Rexrode, K.M.1
  • 10
    • 20244380781 scopus 로고    scopus 로고
    • Low subcutaneous thigh fat is a risk factor for unfavourable glucose and lipid levels, independently of high abdominal fat. The Health ABC Study
    • Snijder MB, et al. Low subcutaneous thigh fat is a risk factor for unfavourable glucose and lipid levels, independently of high abdominal fat. The Health ABC Study. Diabetologia. 2005;48(2):301-308.
    • (2005) Diabetologia , vol.48 , Issue.2 , pp. 301-308
    • Snijder, M.B.1
  • 11
    • 0036072223 scopus 로고    scopus 로고
    • Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients
    • Miyazaki Y, et al. Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab. 2002;87(6):2784-2791.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.6 , pp. 2784-2791
    • Miyazaki, Y.1
  • 12
    • 34848872799 scopus 로고    scopus 로고
    • Obesity-associated improvements in metabolic profile through expansion of adipose tissue
    • Kim JY, et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest. 2007;117(9):2621-2637.
    • (2007) J Clin Invest , vol.117 , Issue.9 , pp. 2621-2637
    • Kim, J.Y.1
  • 13
    • 2942526828 scopus 로고    scopus 로고
    • Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease
    • Klein S, et al. Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. N Engl J Med. 2004;350(25):2549-2557.
    • (2004) N Engl J Med , vol.350 , Issue.25 , pp. 2549-2557
    • Klein, S.1
  • 14
    • 0037382301 scopus 로고    scopus 로고
    • Peripheral adiposity exhibits an independent dominant antiatherogenic effect in elderly women
    • Tanko LB, Bagger YZ, Alexandersen P, Larsen PJ, Christiansen C. Peripheral adiposity exhibits an independent dominant antiatherogenic effect in elderly women. Circulation. 2003;107(12):1626-1631.
    • (2003) Circulation , vol.107 , Issue.12 , pp. 1626-1631
    • Tanko, L.B.1    Bagger, Y.Z.2    Alexandersen, P.3    Larsen, P.J.4    Christiansen, C.5
  • 15
    • 41849094743 scopus 로고    scopus 로고
    • Studies of regional adipose transplantation reveal a unique and beneficial interaction between subcutaneous adipose tissue and the intra-abdominal compartment
    • Hocking SL, Chisholm DJ, James DE. Studies of regional adipose transplantation reveal a unique and beneficial interaction between subcutaneous adipose tissue and the intra-abdominal compartment. Diabetologia. 2008;51(5):900-902.
    • (2008) Diabetologia , vol.51 , Issue.5 , pp. 900-902
    • Hocking, S.L.1    Chisholm, D.J.2    James, D.E.3
  • 16
    • 42649144463 scopus 로고    scopus 로고
    • Beneficial effects of subcutaneous fat transplantation on metabolism
    • Tran TT, Yamamoto Y, Gesta S, Kahn CR. Beneficial effects of subcutaneous fat transplantation on metabolism. Cell Metab. 2008;7(5):410-420.
    • (2008) Cell Metab , vol.7 , Issue.5 , pp. 410-420
    • Tran, T.T.1    Yamamoto, Y.2    Gesta, S.3    Kahn, C.R.4
  • 17
    • 33646271627 scopus 로고    scopus 로고
    • Evidence for a role of developmental genes in the origin of obesity and body fat distribution
    • Gesta S, et al. Evidence for a role of developmental genes in the origin of obesity and body fat distribution. Proc Natl Acad Sci U S A. 2006;103(17):6676-6681.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.17 , pp. 6676-6681
    • Gesta, S.1
  • 18
    • 65649111494 scopus 로고    scopus 로고
    • The origins of brown adipose tissue
    • Enerback S. The origins of brown adipose tissue. N Engl J Med. 2009;360(19):2021-2023.
    • (2009) N Engl J Med , vol.360 , Issue.19 , pp. 2021-2023
    • Enerback, S.1
  • 19
    • 77950226740 scopus 로고    scopus 로고
    • Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes
    • Petrovic N, Walden TB, Shabalina IG, Timmons JA, Cannon B, Nedergaard J. Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J Biol Chem. 2010;285(10):7153-7164.
    • (2010) J Biol Chem , vol.285 , Issue.10 , pp. 7153-7164
    • Petrovic, N.1    Walden, T.B.2    Shabalina, I.G.3    Timmons, J.A.4    Cannon, B.5    Nedergaard, J.6
  • 20
    • 77953010087 scopus 로고    scopus 로고
    • Beige Can Be Slimming
    • Ishibashi J, Seale P. Beige Can Be Slimming. Science. 2010;328(5982):1113-1114.
    • (2010) Science , vol.328 , Issue.5982 , pp. 1113-1114
    • Ishibashi, J.1    Seale, P.2
  • 21
    • 0027051199 scopus 로고
    • Occurrence of brown adipocytes in rat white adipose tissue: Molecular and morphological characterization
    • Cousin B, et al. Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization. J Cell Sci. 1992;103(pt 4):931-942.
    • (1992) J Cell Sci , vol.103 , Issue.PART 4 , pp. 931-942
    • Cousin, B.1
  • 22
    • 0031011161 scopus 로고    scopus 로고
    • Appearance of brown adipocytes in white adipose tissue during CL 316,243-induced reversal of obesity and diabetes in Zucker fa/fa rats
    • Ghorbani M, Himms-Hagen J. Appearance of brown adipocytes in white adipose tissue during CL 316,243-induced reversal of obesity and diabetes in Zucker fa/fa rats. Int J Obes Relat Metab Disord. 1997;21(6):465-475. (Pubitemid 27236965)
    • (1997) International Journal of Obesity , vol.21 , Issue.6 , pp. 465-475
    • Ghorbani, M.1    Himms-Hagen, J.2
  • 23
    • 0032528169 scopus 로고    scopus 로고
    • Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity
    • Guerra C, Koza RA, Yamashita H, Walsh K, Kozak LP. Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. J Clin Invest. 1998;102(2):412-420.
    • (1998) J Clin Invest , vol.102 , Issue.2 , pp. 412-420
    • Guerra, C.1    Koza, R.A.2    Yamashita, H.3    Walsh, K.4    Kozak, L.P.5
  • 26
    • 24344476219 scopus 로고    scopus 로고
    • Transcriptional synergy and the regulation of Ucp1 during brown adipocyte induction in white fat depots
    • Xue B, Coulter A, Rim JS, Koza RA, Kozak LP. Transcriptional synergy and the regulation of Ucp1 during brown adipocyte induction in white fat depots. Mol Cell Biol. 2005;25(18):8311-8322.
    • (2005) Mol Cell Biol , vol.25 , Issue.18 , pp. 8311-8322
    • Xue, B.1    Coulter, A.2    Rim, J.S.3    Koza, R.A.4    Kozak, L.P.5
  • 27
    • 77952623888 scopus 로고    scopus 로고
    • The emergence of cold-induced brown adipocytes in mouse white fat depots is predominantly determined by white to brown adipocyte transdifferentiation
    • Barbatelli G, et al. The emergence of cold-induced brown adipocytes in mouse white fat depots is predominantly determined by white to brown adipocyte transdifferentiation. Am J Physiol Endocrinol Metab. 2010;298(6):E1244-E1253.
    • (2010) Am J Physiol Endocrinol Metab , vol.298 , Issue.6
    • Barbatelli, G.1
  • 28
    • 0031025546 scopus 로고    scopus 로고
    • Strain-specific response to beta 3-adrenergic receptor agonist treatment of diet-induced obesity in mice
    • Collins S, Daniel KW, Petro AE, Surwit RS. Strain-specific response to beta 3-adrenergic receptor agonist treatment of diet-induced obesity in mice. Endocrinology. 1997;138(1):405-413.
    • (1997) Endocrinology , vol.138 , Issue.1 , pp. 405-413
    • Collins, S.1    Daniel, K.W.2    Petro, A.E.3    Surwit, R.S.4
  • 29
    • 0027268150 scopus 로고
    • Adipose tissues from various anatomical sites are characterized by different patterns of gene expression and regulation
    • Cousin B, Casteilla L, Dani C, Muzzin P, Revelli JP, Penicaud L. Adipose tissues from various anatomical sites are characterized by different patterns of gene expression and regulation. Biochem J. 1993;292(pt 3):873-876.
    • (1993) Biochem J , vol.292 , Issue.PART 3 , pp. 873-876
    • Cousin, B.1    Casteilla, L.2    Dani, C.3    Muzzin, P.4    Revelli, J.P.5    Penicaud, L.6
  • 30
    • 33751199972 scopus 로고    scopus 로고
    • The adipose organ of SV129 mice contains a prevalence of brown adipocytes and shows plasticity after cold exposure
    • Murano I, Zingaretti MC, Cinti S. The adipose organ of SV129 mice contains a prevalence of brown adipocytes and shows plasticity after cold exposure. Adipocytes. 2005;1:121-130.
    • (2005) Adipocytes , vol.1 , pp. 121-130
    • Murano, I.1    Zingaretti, M.C.2    Cinti, S.3
  • 31
    • 50049122271 scopus 로고    scopus 로고
    • PRDM16 controls a brown fat/skeletal muscle switch
    • Seale P, et al. PRDM16 controls a brown fat/skeletal muscle switch. Nature. 2008;454(7207):961-967.
    • (2008) Nature , vol.454 , Issue.7207 , pp. 961-967
    • Seale, P.1
  • 32
    • 0037304599 scopus 로고    scopus 로고
    • Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone
    • Wilson-Fritch L, et al. Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone. Mol Cell Biol. 2003;23(3):1085-1094.
    • (2003) Mol Cell Biol , vol.23 , Issue.3 , pp. 1085-1094
    • Wilson-Fritch, L.1
  • 33
    • 85047689659 scopus 로고    scopus 로고
    • Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone
    • Wilson-Fritch L, et al. Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone. J Clin Invest. 2004;114(9):1281-1289.
    • (2004) J Clin Invest , vol.114 , Issue.9 , pp. 1281-1289
    • Wilson-Fritch, L.1
  • 34
    • 0034085884 scopus 로고    scopus 로고
    • A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice
    • Fukui Y, Masui S, Osada S, Umesono K, Motojima K. A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice. Diabetes. 2000;49(5):759-767.
    • (2000) Diabetes , vol.49 , Issue.5 , pp. 759-767
    • Fukui, Y.1    Masui, S.2    Osada, S.3    Umesono, K.4    Motojima, K.5
  • 35
    • 13844262924 scopus 로고    scopus 로고
    • Corepressors selectively control the transcrip tional activity of PPARgamma in adipocytes
    • Guan HP, Ishizuka T, Chui PC, Lehrke M, Lazar MA. Corepressors selectively control the transcrip tional activity of PPARgamma in adipocytes. Genes Dev. 2005;19(4):453-461.
    • (2005) Genes Dev , vol.19 , Issue.4 , pp. 453-461
    • Guan, H.P.1    Ishizuka, T.2    Chui, P.C.3    Lehrke, M.4    Lazar, M.A.5
  • 37
    • 68849107400 scopus 로고    scopus 로고
    • C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists
    • Vernochet C, et al. C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists. Mol Cell Biol. 2009;29(17):4714-4728.
    • (2009) Mol Cell Biol , vol.29 , Issue.17 , pp. 4714-4728
    • Vernochet, C.1
  • 38
    • 17944377509 scopus 로고    scopus 로고
    • FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance
    • Cederberg A, Gronning LM, Ahren B, Tasken K, Carlsson P, Enerback S. FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance. Cell. 2001;106(5):563-573.
    • (2001) Cell , vol.106 , Issue.5 , pp. 563-573
    • Cederberg, A.1    Gronning, L.M.2    Ahren, B.3    Tasken, K.4    Carlsson, P.5    Enerback, S.6
  • 39
    • 0037151047 scopus 로고    scopus 로고
    • Mechanisms of FOXC2- and FOXD1-mediated regulation of the RI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by protein kinase B alpha and cAMP
    • Dahle MK, et al. Mechanisms of FOXC2- and FOXD1-mediated regulation of the RI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by protein kinase B alpha and cAMP. J Biol Chem. 2002;277(25):22902-22908.
    • (2002) J Biol Chem , vol.277 , Issue.25 , pp. 22902-22908
    • Dahle, M.K.1
  • 40
    • 77952970098 scopus 로고    scopus 로고
    • Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes
    • Vegiopoulos A, et al. Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes. Science. 2010; 328(5982):1158-1161.
    • (2010) Science , vol.328 , Issue.5982 , pp. 1158-1161
    • Vegiopoulos, A.1
  • 42
    • 12144287013 scopus 로고    scopus 로고
    • Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation
    • Hansen JB, et al. Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation. Proc Natl Acad Sci U S A. 2004;101(12):4112-4117.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.12 , pp. 4112-4117
    • Hansen, J.B.1
  • 43
    • 33645064540 scopus 로고    scopus 로고
    • Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha
    • Scime A, et al. Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha. Cell Metab. 2005;2(5):283-295.
    • (2005) Cell Metab , vol.2 , Issue.5 , pp. 283-295
    • Scime, A.1
  • 44
    • 0034770191 scopus 로고    scopus 로고
    • Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1
    • Tsukiyama-Kohara K, et al. Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1. Nat Med. 2001;7(10):1128-1132.
    • (2001) Nat Med , vol.7 , Issue.10 , pp. 1128-1132
    • Tsukiyama-Kohara, K.1
  • 45
    • 41149117092 scopus 로고    scopus 로고
    • Liver X receptor alpha is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype
    • Wang H, et al. Liver X receptor alpha is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype. Mol Cell Biol. 2008;28(7):2187-2200.
    • (2008) Mol Cell Biol , vol.28 , Issue.7 , pp. 2187-2200
    • Wang, H.1
  • 46
    • 31044432605 scopus 로고    scopus 로고
    • Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes
    • Powelka AM, et al. Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. J Clin Invest. 2006;116(1):125-136.
    • (2006) J Clin Invest , vol.116 , Issue.1 , pp. 125-136
    • Powelka, A.M.1
  • 47
    • 73649094118 scopus 로고    scopus 로고
    • Deletion of tumor necrosis factor-alpha-receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis
    • Romanatto T, et al. Deletion of tumor necrosis factor-alpha-receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis. J Biol Chem. 2009;284(52):36213-36222.
    • (2009) J Biol Chem , vol.284 , Issue.52 , pp. 36213-36222
    • Romanatto, T.1
  • 48
    • 70449448312 scopus 로고    scopus 로고
    • Autophagy regulates adipose mass and differentiation in mice
    • Singh R, et al. Autophagy regulates adipose mass and differentiation in mice. J Clin Invest. 2009;119(11):3329-3339.
    • (2009) J Clin Invest , vol.119 , Issue.11 , pp. 3329-3339
    • Singh, R.1
  • 49
    • 69449097633 scopus 로고    scopus 로고
    • The protein kinase IKKepsilon regulates energy balance in obese mice
    • Chiang SH, et al. The protein kinase IKKepsilon regulates energy balance in obese mice. Cell. 2009;138(5):961-975.
    • (2009) Cell , vol.138 , Issue.5 , pp. 961-975
    • Chiang, S.H.1
  • 50
    • 2942532305 scopus 로고    scopus 로고
    • Nuclear receptor corepressor RIP140 regulates fat accumulation
    • Leonardsson G, et al. Nuclear receptor corepressor RIP140 regulates fat accumulation. Proc Natl Acad Sci U S A. 2004;101(22):8437-8442.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.22 , pp. 8437-8442
    • Leonardsson, G.1
  • 51
    • 63049083171 scopus 로고    scopus 로고
    • Twist-1 is a PPARdelta-inducible, negative-feedback regulator of PGC-1alpha in brown fat metabolism
    • Pan D, Fujimoto M, Lopes A, Wang YX. Twist-1 is a PPARdelta-inducible, negative-feedback regulator of PGC-1alpha in brown fat metabolism. Cell. 2009;137(1):73-86.
    • (2009) Cell , vol.137 , Issue.1 , pp. 73-86
    • Pan, D.1    Fujimoto, M.2    Lopes, A.3    Wang, Y.X.4
  • 52
    • 51449123610 scopus 로고    scopus 로고
    • Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice
    • Toh SY, et al. Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice. PLoS One. 2008;3(8):e2890.
    • (2008) PLoS One , vol.3 , Issue.8
    • Toh, S.Y.1
  • 53
    • 34347326271 scopus 로고    scopus 로고
    • Transcriptional control of brown fat determination by PRDM16
    • Seale P, et al. Transcriptional control of brown fat determination by PRDM16. Cell Metab. 2007;6(1):38-54.
    • (2007) Cell Metab , vol.6 , Issue.1 , pp. 38-54
    • Seale, P.1
  • 54
    • 44149113548 scopus 로고    scopus 로고
    • Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex
    • Kajimura S, et al. Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes Dev. 2008;22(10):1397-1409.
    • (2008) Genes Dev , vol.22 , Issue.10 , pp. 1397-1409
    • Kajimura, S.1
  • 55
    • 69349088117 scopus 로고    scopus 로고
    • Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex
    • Kajimura S, et al. Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex. Nature. 2009;460(7259):1154-1158.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1154-1158
    • Kajimura, S.1
  • 56
    • 77950344582 scopus 로고    scopus 로고
    • The engineering of brown fat
    • Christian M, Parker MG. The engineering of brown fat. J Mol Cell Biol. 2010;2(1):23-25.
    • (2010) J Mol Cell Biol , vol.2 , Issue.1 , pp. 23-25
    • Christian, M.1    Parker, M.G.2
  • 57
    • 0035905758 scopus 로고    scopus 로고
    • The hormone resistin links obesity to diabetes
    • Steppan CM, et al. The hormone resistin links obesity to diabetes. Nature. 2001;409(6818):307-312.
    • (2001) Nature , vol.409 , Issue.6818 , pp. 307-312
    • Steppan, C.M.1
  • 58
    • 77449101244 scopus 로고    scopus 로고
    • A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes
    • Butler AA, Kozak LP. A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes. Diabetes. 2010;59(2):323-329.
    • (2010) Diabetes , vol.59 , Issue.2 , pp. 323-329
    • Butler, A.A.1    Kozak, L.P.2
  • 59
    • 0022831821 scopus 로고
    • Determinants of 24-hour energy expenditure in man. Methods and results using a respiratory chamber
    • Ravussin E, Lillioja S, Anderson TE, Christin L, Bogardus C. Determinants of 24-hour energy expenditure in man. Methods and results using a respiratory chamber. J Clin Invest. 1986;78(6):1568-1578.
    • (1986) J Clin Invest , vol.78 , Issue.6 , pp. 1568-1578
    • Ravussin, E.1    Lillioja, S.2    Anderson, T.E.3    Christin, L.4    Bogardus, C.5
  • 61
    • 58149337340 scopus 로고    scopus 로고
    • Noradrenergic parenchymal nerve fiber branching after cold acclimatisation correlates with brown adipocyte density in mouse adipose organ
    • Murano I, Barbatelli G, Giordano A, Cinti S. Noradrenergic parenchymal nerve fiber branching after cold acclimatisation correlates with brown adipocyte density in mouse adipose organ. J Anat. 2009;214(1):171-178.
    • (2009) J Anat , vol.214 , Issue.1 , pp. 171-178
    • Murano, I.1    Barbatelli, G.2    Giordano, A.3    Cinti, S.4
  • 62
    • 0020062871 scopus 로고
    • Initiation, duration and dissipation of diet-induced changes in sympathetic nervous system activity in the rat
    • Rappaport EB, Young JB, Landsberg L. Initiation, duration and dissipation of diet-induced changes in sympathetic nervous system activity in the rat. Metabolism. 1982;31(2):143-146. (Pubitemid 12222529)
    • (1982) Metabolism: Clinical and Experimental , vol.31 , Issue.2 , pp. 143-146
    • Rappaport, E.B.1    Young, J.B.2    Landsberg, L.3
  • 63
    • 0019483909 scopus 로고
    • Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man
    • Rowe JW, Young JB, Minaker KL, Stevens AL, Pallotta J, Landsberg L. Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man. Diabetes. 1981;30(3):219-225.
    • (1981) Diabetes , vol.30 , Issue.3 , pp. 219-225
    • Rowe, J.W.1    Young, J.B.2    Minaker, K.L.3    Stevens, A.L.4    Pallotta, J.5    Landsberg, L.6
  • 64
    • 0020529027 scopus 로고
    • Effect of dietary fat on sympathetic nervous system activity in the rat
    • Schwartz JH, Young JB, Landsberg L. Effect of dietary fat on sympathetic nervous system activity in the rat. J Clin Invest. 1983;72(1):361-370. (Pubitemid 13025877)
    • (1983) Journal of Clinical Investigation , vol.72 , Issue.1 , pp. 361-370
    • Schwartz, J.H.1    Young, J.B.2    Landsberg, L.3
  • 65
    • 0020051648 scopus 로고
    • Effect of diet and cold exposure on norepinephrine turnover in brown adipose tissue of the rat
    • Young JB, Saville E, Rothwell NJ, Stock MJ, Landsberg L. Effect of diet and cold exposure on norepinephrine turnover in brown adipose tissue of the rat. J Clin Invest. 1982;69(5):1061-1071.
    • (1982) J Clin Invest , vol.69 , Issue.5 , pp. 1061-1071
    • Young, J.B.1    Saville, E.2    Rothwell, N.J.3    Stock, M.J.4    Landsberg, L.5
  • 66
    • 64349105205 scopus 로고    scopus 로고
    • Identification and importance of brown adipose tissue in adult humans
    • Cypess AM, et al. Identification and importance of brown adipose tissue in adult humans. N Engl J Med. 2009;360(15):1509-1517.
    • (2009) N Engl J Med , vol.360 , Issue.15 , pp. 1509-1517
    • Cypess, A.M.1
  • 67
    • 67650242165 scopus 로고    scopus 로고
    • High incidence of metabolically active brown adipose tissue in healthy adult humans: Effects of cold exposure and adiposity
    • Saito M, et al. High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes. 2009;58(7):1526-1531.
    • (2009) Diabetes , vol.58 , Issue.7 , pp. 1526-1531
    • Saito, M.1
  • 68
    • 64349095231 scopus 로고    scopus 로고
    • Cold-activated brown adipose tissue in healthy men
    • van Marken Lichtenbelt WD, et al. Cold-activated brown adipose tissue in healthy men. N Engl J Med. 2009;360(15):1500-1508.
    • (2009) N Engl J Med , vol.360 , Issue.15 , pp. 1500-1508
    • Van Marken Lichtenbelt, W.D.1
  • 69
    • 64349123664 scopus 로고    scopus 로고
    • Functional brown adipose tissue in healthy adults
    • Virtanen KA, et al. Functional brown adipose tissue in healthy adults. N Engl J Med. 2009;360(15):1518-1525.
    • (2009) N Engl J Med , vol.360 , Issue.15 , pp. 1518-1525
    • Virtanen, K.A.1
  • 70
    • 67651166870 scopus 로고    scopus 로고
    • The importance of brown adipose tissue
    • Timmons JA, Pedersen BK. The importance of brown adipose tissue. N Engl J Med. 2009;361(4):415-416.
    • (2009) N Engl J Med , vol.361 , Issue.4 , pp. 415-416
    • Timmons, J.A.1    Pedersen, B.K.2
  • 71
    • 78651166782 scopus 로고
    • Metabolism of isolated fat cells. I. Effects of hormones on glucose metabolism and lipolysis
    • Rodbell M. Metabolism of isolated fat cells. I. Effects of hormones on glucose metabolism and lipolysis. J Biol Chem. 1964;239:375-380.
    • (1964) J Biol Chem , vol.239 , pp. 375-380
    • Rodbell, M.1
  • 72
    • 0035823625 scopus 로고    scopus 로고
    • Distinct transcriptional profiles of adipogenesis in vivo and in vitro
    • Soukas A, Socci ND, Saatkamp BD, Novelli S, Friedman JM. Distinct transcriptional profiles of adipogenesis in vivo and in vitro. J Biol Chem. 2001;276(36):34167-34174.
    • (2001) J Biol Chem , vol.276 , Issue.36 , pp. 34167-34174
    • Soukas, A.1    Socci, N.D.2    Saatkamp, B.D.3    Novelli, S.4    Friedman, J.M.5
  • 73
    • 19444367043 scopus 로고    scopus 로고
    • Regional-dependent increase of sympathetic innervation in rat white adipose tissue during prolonged fasting
    • Giordano A, et al. Regional-dependent increase of sympathetic innervation in rat white adipose tissue during prolonged fasting. J Histochem Cytochem. 2005;53(6):679-687.
    • (2005) J Histochem Cytochem , vol.53 , Issue.6 , pp. 679-687
    • Giordano, A.1


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