Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes

Diabetologia

Volumn 55, Issue 9, 2012, Pages 2456-2468

  Lee, Y S ^a   Park, M S ^a   Choung, J S ^a   Kim, S S ^a   Oh, H H ^a   Choi, C S ^a   Ha, S Y ^a   Kang, Y ^b   Kim, Y ^c   Jun, H S ^a  

^a Gachon University College of Medicine   (South Korea)

^b Ajou University School of Medicine   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Adipose tissue; Adipose tissue macrophage; Anti inflammatory; Cytokine; Glucagon like peptide 1; Inflammatory signalling; Insulin resistance; Lipogenic genes; M1; M2 macrophage

Indexed keywords

ADENOVIRUS VECTOR; CD11B ANTIGEN; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHROPOMETRIC PARAMETERS; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BODY FAT MASS; CELL INFILTRATION; CELL SIZE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETES MELLITUS; ENZYME ACTIVATION; GENE; GENE EXPRESSION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPOGENIC GENE; M1 MACROPHAGE SPECIFIC GENE; M2 MACROPHAGE SPECIFIC GENE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS RECOMBINANT;

ADIPOSE TISSUE; ANIMALS; ANTI-INFLAMMATORY AGENTS; BODY FAT DISTRIBUTION; GENE EXPRESSION REGULATION; GLUCAGON-LIKE PEPTIDE 1; INFLAMMATION; INSULIN RESISTANCE; MACROPHAGES; MICE; MICE, OBESE; NF-KAPPA B; OBESITY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, GLUCAGON;

EID: 84866055251     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2592-3     Document Type: Article

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