A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Nature

Volumn 481, Issue 7382, 2012, Pages 463-468

  Boström, Pontus ^a   Wu, Jun ^a   Jedrychowski, Mark P ^a   Korde, Anisha ^a   Ye, Li ^a   Lo, James C ^a   Rasbach, Kyle A ^a   Boström, Elisabeth Almer ^b   Choi, Jang Hyun ^a   Long, Jonathan Z ^a   Kajimura, Shingo ^c   Zingaretti, Maria Cristina ^d   Vind, Birgitte F ^e   Tu, Hua ^f   Cinti, Saverio ^d   Højlund, Kurt ^e   Gygi, Steven P ^a   Spiegelman, Bruce M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^e ODENSE UNIVERSITY HOSPITAL   (Denmark)

^f LakePharma Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HORMONE; IRISIN; MEMBRANE PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN FNDC 5; UNCLASSIFIED DRUG;

BLOOD; ENERGY EFFICIENCY; FAT; GENE EXPRESSION; GLUCOSE; HOMEOSTASIS; HORMONE; METABOLISM; MUSCLE; OBESITY; PROTEIN; RODENT;

ARTICLE; BROWN ADIPOSE TISSUE; DOWNSTREAM PROCESSING; ENERGY EXPENDITURE; FOOD INTAKE; GLUCOSE HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; MUSCLE CELL; MUSCLE EXCITATION; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; THERMOGENESIS; WHITE ADIPOSE TISSUE;

ADIPOCYTES; ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; ANIMALS; CELL RESPIRATION; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; ENERGY METABOLISM; EXERCISE; GENE EXPRESSION REGULATION; HORMONES; HUMANS; INSULIN RESISTANCE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ION CHANNELS; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MITOCHONDRIAL PROTEINS; MODELS, ANIMAL; MUSCLE CELLS; OBESITY; PHYSICAL CONDITIONING, ANIMAL; PLASMA; SUBCUTANEOUS FAT; THERMOGENESIS; TRANS-ACTIVATORS;

MAMMALIA; MUS;

EID: 84862776702     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10777     Document Type: Article

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