Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

Nature Immunology

Volumn 15, Issue 5, 2014, Pages 423-430

  Mauer, Jan ^a,b,c   Chaurasia, Bhagirath ^a   Goldau, Julia ^a   Vogt, Merly C ^a,b,c   Ruud, Johan ^a,b,c   Nguyen, Khoa D ^d   Theurich, Sebastian ^a,b,c   Hausen, A Christine ^a,b,c   Schmitz, Joel ^a,e   Brönneke, Hella S ^b,c   Estevez, Emma ^f   Allen, Tamara L ^f   Mesaros, Andrea ^g   Partridge, Linda ^g   Febbraio, Mark A ^f   Chawla, Ajay ^d   Wunderlich, F Thomas ^a,b,c   Brüning, Jens C ^a,b,c,e  

^a UNIVERSITY OF COLOGNE   (Germany)

^b MAX PLANCK INSTITUTE FOR NEUROLOGICAL RESEARCH   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^f BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^g MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; CELLS, CULTURED; ENDOTOXEMIA; HUMANS; INSULIN RESISTANCE; INTERLEUKIN-4; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; OBESITY; RECEPTORS, INTERLEUKIN-6; SIGNAL TRANSDUCTION;

EID: 84899124414     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2865     Document Type: Article

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