Effects of adipocyte lipoprotein lipase on de novo lipogenesis and white adipose tissue browning

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1831, Issue 5, 2013, Pages 934-942

  Bartelt, Alexander ^a   Weigelt, Clara ^a   Cherradi, M Lisa ^a   Niemeier, Andreas ^a   Tödter, Klaus ^a   Heeren, Joerg ^a   Scheja, Ludger ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Brown adipose tissue; De novo lipogenesis; Fatty acid; Insulin resistance; Lipoprotein lipase; Obesity

Indexed keywords

ADIPOCYTOKINE; BETA 3 ADRENERGIC RECEPTOR; CARBOHYDRATE; FATTY ACID; INSULIN; LIPOPROTEIN LIPASE; PALMITOLEIC ACID; TRANSCRIPTION FACTOR;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FAT INTAKE; FATTY ACID TRANSPORT; GENE EXPRESSION; GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; LIPID DIET; LIPOGENESIS; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; WHITE ADIPOSE TISSUE;

ADIPOCYTES; ADIPOGENESIS; ADIPOKINES; ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; ADRENERGIC BETA-3 RECEPTOR AGONISTS; ANIMALS; DIET, HIGH-FAT; DIOXOLES; GLUCOSE TOLERANCE TEST; HYPERTRIGLYCERIDEMIA; LIPIDS; LIPOGENESIS; LIPOPROTEIN LIPASE; LIPOPROTEINS; MICE; MICE, KNOCKOUT; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRIGLYCERIDES;

ANIMALIA; MUS;

EID: 84875852161     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2012.11.011     Document Type: Article

References (51)

1. T. Coleman, R.L. Seip, J.M. Gimble, D. Lee, N. Maeda, and C.F. Semenkovich COOH-terminal disruption of lipoprotein lipase in mice is lethal in homozygotes, but heterozygotes have elevated triglycerides and impaired enzyme activity J. Biol. Chem. 270 1995 12518 12525
2. S. Levak-Frank, P.H. Weinstock, T. Hayek, R. Verdery, W. Hofmann, R. Ramakrishnan, W. Sattler, J.L. Breslow, and R. Zechner Induced mutant mice expressing lipoprotein lipase exclusively in muscle have subnormal triglycerides yet reduced high density lipoprotein cholesterol levels in plasma J. Biol. Chem. 272 1997 17182 17190
3. P.H. Weinstock, S. Levak-Frank, L.C. Hudgins, H. Radner, J.M. Friedman, R. Zechner, and J.L. Breslow Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase Proc. Natl. Acad. Sci. U. S. A. 94 1997 10261 10266
4. A.P. Beigneux, B.S. Davies, P. Gin, M.M. Weinstein, E. Farber, X. Qiao, F. Peale, S. Bunting, R.L. Walzem, J.S. Wong, W.S. Blaner, Z.M. Ding, K. Melford, N. Wongsiriroj, X. Shu, F. de Sauvage, R.O. Ryan, L.G. Fong, A. Bensadoun, and S.G. Young Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons Cell Metab. 5 2007 279 291
5. B.S. Davies, A.P. Beigneux, R.H. Barnes II, Y. Tu, P. Gin, M.M. Weinstein, C. Nobumori, R. Nyrén, I. Goldberg, G. Olivecrona, A. Bensadoun, S.G. Young, and L.G. Fong GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries Cell Metab. 12 2010 42 52
6. A.P. Beigneux, R. Franssen, A. Bensadoun, P. Gin, K. Melford, J. Peter, R.L. Walzem, M.M. Weinstein, B.S. Davies, J.A. Kuivenhoven, J.J. Kastelein, L.G. Fong, G.M. Dallinga-Thie, and S.G. Young Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase Arterioscler. Thromb. Vasc. Biol. 29 2009 956 962
7. P.J. Voshol, P.C. Rensen, K.W. van Dijk, J.A. Romijn, and L.M. Havekes Effect of plasma triglyceride metabolism on lipid storage in adipose tissue: studies using genetically engineered mouse models Biochim. Biophys. Acta 1791 2009 479 485
8. I. Duivenvoorden, B. Teusink, P.C. Rensen, J.A. Romijn, L.M. Havekes, and P.J. Voshol Apolipoprotein C3 deficiency results in diet-induced obesity and aggravated insulin resistance in mice Diabetes 54 2005 664 671
9. M.C. Jong, P.J. Voshol, M. Muurling, V.E. Dahlmans, J.A. Romijn, H. Pijl, and L.M. Havekes Protection from obesity and insulin resistance in mice overexpressing human apolipoprotein C1 Diabetes 50 2001 2779 2785
10. G.S. Hotamisligil Inflammation and metabolic disorderss Nature 444 2006 860 867
11. A. Bartelt, and J. Heeren The holy grail of metabolic disease: brown adipose tissue Curr. Opin. Lipidol. 23 2012 190 195
12. A. Bartelt, O.T. Bruns, R. Reimer, H. Hohenberg, H. Ittrich, K. Peldschus, M.G. Kaul, U.I. Tromsdorf, H. Weller, C. Waurisch, A. Eychmüller, P.L. Gordts, F. Rinninger, K. Bruegelmann, B. Freund, P. Nielsen, M. Merkel, and J. Heeren Brown adipose tissue activity controls triglyceride clearance Nat. Med. 17 2011 200 205
13. S. Kajimura, P. Seale, and B.M. Spiegelman Transcriptional control of brown fat development Cell Metab. 11 2010 257 262
14. S. Cinti The adipose organ at a glance Dis. Model. Mech. 5 2012 588 594
15. W. Cao, K.W. Daniel, J. Robidoux, P. Puigserver, A.V. Medvedev, X. Bai, L.M. Floering, B.M. Spiegelman, and S. Collins p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene Mol. Cell. Biol. 24 2004 3057 3067
16. M. Bordicchia, D. Liu, E.Z. Amri, G. Ailhaud, P. Dessì-Fulgheri, C. Zhang, N. Takahashi, R. Sarzani, and S. Collins Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes J. Clin. Invest. 122 2012 1022 1036
17. P. Boström, J. Wu, M.P. Jedrychowski, A. Korde, L. Ye, J.C. Lo, K.A. Rasbach, E.A. Boström, J.H. Choi, J.Z. Long, S. Kajimura, M.C. Zingaretti, B.F. Vind, H. Tu, S. Cinti, K. Højlund, S.P. Gygi, and B.M. Spiegelman A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis Nature 481 2012 463 468
18. D. Richard, and F. Picard Brown fat biology and thermogenesis Front. Biosci. 16 2011 1233 1260
19. E.P. Mottillo, A.E. Bloch, T. Leff, and J.G. Granneman Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply J. Biol. Chem. 287 2012 25038 25048
20. M.A. Christoffolete, C.C. Linardi, L. de Jesus, K.N. Ebina, S.D. Carvalho, M.O. Ribeiro, R. Rabelo, C. Curcio, L. Martins, E.T. Kimura, and A.C. Bianco Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis Diabetes 53 2004 577 584
21. R. Westerberg, J.E. Månsson, V. Golozoubova, I.G. Shabalina, E.C. Backlund, P. Tvrdik, K. Retterstøl, M.R. Capecchi, and A. Jacobsson ELOVL3 is an important component for early onset of lipid recruitment in brown adipose tissue J. Biol. Chem. 281 2006 4958 4968
22. H.C. Freake, H.L. Schwartz, and J.H. Oppenheimer The regulation of lipogenesis by thyroid hormone and its contribution to thermogenesis Endocrinology 125 1989 2868 2874
23. A.C. Bianco, S.D. Carvalho, C.R. Carvalho, R. Rabelo, and A.S. Moriscot Thyroxine 5′-deiodination mediates norepinephrine-induced lipogenesis in dispersed brown adipocytes Endocrinology 139 1998 571 578
24. L. Scheja, B. Heese, and K. Seedorf Beneficial effects of IKKε-deficiency on body weight and insulin sensitivity are lost in high fat diet-induced obesity in mice Biochem. Biophys. Res. Commun. 407 2011 288 294
25. A. Bartelt, P. Orlando, C. Mele, A. Ligresti, K. Toedter, L. Scheja, J. Heeren, and V. Di Marzo Altered endocannabinoid signalling after a high-fat diet in Apoe(-/-) mice: relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance Diabetologia 54 2011 2900 2910
26. J. Folch, M. Lees, and G.H. Sloane Stanley A simple method for the isolation and purification of total lipides from animal tissues J. Biol. Chem. 226 1957 497 509
27. G. Lepage, and C.C. Roy Direct transesterification of all classes of lipids in a one-step reaction J. Lipid Res. 27 1986 114 120
28. M.A. Herman, O.D. Peroni, J. Villoria, M.R. Schön, N.A. Abumrad, M. Blüher, S. Klein, and B.B. Kahn A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism Nature 484 2012 333 338
29. L. Makowski, J.B. Boord, K. Maeda, V.R. Babaev, K.T. Uysal, M.A. Morgan, R.A. Parker, J. Suttles, S. Fazio, G.S. Hotamisligil, and M.F. Linton Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis Nat. Med. 7 2001 699 705
30. M.S. Rolph, T.R. Young, B.O. Shum, C.Z. Gorgun, C. Schmitz-Peiffer, I.A. Ramshaw, G.S. Hotamisligil, and C.R. Mackay Regulation of dendritic cell function and T cell priming by the fatty acid-binding protein AP2 J. Immunol. 177 2006 7794 7801
31. D. Kratky, R. Zimmermann, E.M. Wagner, J.G. Strauss, W. Jin, G.M. Kostner, G. Haemmerle, D.J. Rader, and R. Zechner Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue J. Clin. Invest. 115 2005 161 167
32. M.M. Weinstein, C.N. Goulbourne, B.S. Davies, Y. Tu, R.H. Barnes II, S.M. Watkins, R. Davis, K. Reue, P. Tontonoz, A.P. Beigneux, L.G. Fong, and S.G. Young Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice Arterioscler. Thromb. Vasc. Biol. 32 2012 230 235
33. H. Yamashita, M. Takenoshita, M. Sakurai, R.K. Bruick, W.J. Henzel, W. Shillinglaw, D. Arnot, and K. Uyeda A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver Proc. Natl. Acad. Sci. U. S. A. 98 2001 9116 9121
34. E. Erbay, V.R. Babaev, J.R. Mayers, L. Makowski, K.N. Charles, M.E. Snitow, S. Fazio, M.M. Wiest, S.M. Watkins, M.F. Linton, and G.S. Hotamisligil Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis Nat. Med. 15 2009 1383 1391
35. X. Guo, H. Li, H. Xu, V. Halim, W. Zhang, H. Wang, K.T. Ong, S.L. Woo, R.L. Walzem, D.G. Mashek, H. Dong, F. Lu, L. Wei, Y. Huo, and C. Wu Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice PLoS One 7 2012 e39286
36. H. Xu, G.T. Barnes, Q. Yang, G. Tan, D. Yang, C.J. Chou, J. Sole, A. Nichols, J.S. Ross, L.A. Tartaglia, and H. Chen Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance J. Clin. Invest. 112 2003 1821 1830
37. S.P. Weisberg, D. McCann, M. Desai, M. Rosenbaum, R.L. Leibel, and A.W. Ferrante Jr. Obesity is associated with macrophage accumulation in adipose tissue J. Clin. Invest. 112 2003 1796 1808
38. A.M. Ostlund-Lindqvist, S. Gustafson, P. Lindqvist, J.L. Witztum, and J.A. Little Uptake and degradation of human chylomicrons by macrophages in culture. Role of lipoprotein lipase Arteriosclerosis 3 1983 433 440
39. N.F. Ullrich, J.Q. Purnell, and J.D. Brunzell Adipose tissue fatty acid composition in humans with lipoprotein lipase deficiency J. Investig. Med. 49 2001 273 275
40. N. Yahagi, H. Shimano, A.H. Hasty, M. Amemiya-Kudo, H. Okazaki, Y. Tamura, Y. Iizuka, F. Shionoiri, K. Ohashi, J. Osuga, K. Harada, T. Gotoda, R. Nagai, S. Ishibashi, and N. Yamada A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids J. Biol. Chem. 274 1999 35840 35844
41. Y.S. Moon, M.J. Latasa, M.J. Griffin, and H.S. Sul Suppression of fatty acid synthase promoter by polyunsaturated fatty acids J. Lipid Res. 43 2002 691 698
42. R. Dentin, F. Benhamed, J.P. Pégorier, F. Foufelle, B. Viollet, S. Vaulont, J. Girard, and C. Postic Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation J. Clin. Invest. 115 2005 2843 2854
43. H. Cao, K. Gerhold, J.R. Mayers, M.M. Wiest, S.M. Watkins, and G.S. Hotamisligil Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism Cell 134 2008 933 944
44. Z.H. Yang, H. Miyahara, and A. Hatanaka Chronic administration of palmitoleic acid reduces insulin resistance and hepatic lipid accumulation in KK-Ay Mice with genetic type 2 diabetes Lipids Health Dis. 10 2011 120
45. S.A. Summers Ceramides in insulin resistance and lipotoxicity Prog. Lipid Res. 45 2006 42 72
46. M.B. Fessler, L.L. Rudel, and J.M. Brown Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome Curr. Opin. Lipidol. 20 2009 379 385
47. S.A. van den Berg, B. Guigas, S. Bijland, M. Ouwens, P.J. Voshol, R.R. Frants, L.M. Havekes, J.A. Romijn, and K.W. van Dijk High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity Nutr. Metab. (Lond.) 7 2010 24
48. X. Liu, M. Miyazaki, M.T. Flowers, H. Sampath, M. Zhao, K. Chu, C.M. Paton, D.S. Joo, and J.M. Ntambi Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate Arterioscler. Thromb. Vasc. Biol. 30 2010 31 38
49. S. Virtue, and A. Vidal-Puig Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome - an allostatic perspective Biochim. Biophys. Acta 1801 2010 338 349
50. H. Wang, G. Astarita, M.D. Taussig, K.G. Bharadwaj, N.V. DiPatrizio, K.A. Nave, D. Piomelli, I.J. Goldberg, and R.H. Eckel Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity Cell Metab. 13 2011 105 113
51. A. Vegiopoulos, K. Müller-Decker, D. Strzoda, I. Schmitt, E. Chichelnitskiy, A. Ostertag, M. Berriel Diaz, J. Rozman, M. Hrabe de Angelis, R.M. Nüsing, C.W. Meyer, W. Wahli, M. Klingenspor, and S. Herzig Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes Science 328 2010 1158 1161