메뉴 건너뛰기




Volumn 304, Issue 8, 2013, Pages

Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes

Author keywords

CRE; ERK; Inflammation; Promoter activity; TNF

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYTOKINE; ISOPRENALINE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCOUPLING PROTEIN 1;

EID: 84878650010     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00312.2012     Document Type: Article
Times cited : (100)

References (46)
  • 1
    • 33847768085 scopus 로고    scopus 로고
    • Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice
    • Almind K, Manieri M, Sivitz WI, Cinti S, Kahn CR. Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice. Proc Natl Acad Sci USA 104: 2366-2371, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 2366-2371
    • Almind, K.1    Manieri, M.2    Sivitz, W.I.3    Cinti, S.4    Kahn, C.R.5
  • 4
    • 14544298335 scopus 로고    scopus 로고
    • The role of MAPKs in adipocyte differentiation and obesity
    • Bost F, Aouadi M, Caron L, Binetruy B. The role of MAPKs in adipocyte differentiation and obesity. Biochimie 87: 51-56, 2005.
    • (2005) Biochimie , vol.87 , pp. 51-56
    • Bost, F.1    Aouadi, M.2    Caron, L.3    Binetruy, B.4
  • 5
    • 1642293248 scopus 로고    scopus 로고
    • Collins S. p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene
    • Cao W, Daniel KW, Robidoux J, Puigserver P, Medvedev AV, Bai X, Floering LM, Spiegelman BM, Collins S. p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. Mol Cell Biol 24: 3057-3067, 2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 3057-3067
    • Cao, W.1    Daniel, K.W.2    Robidoux, J.3    Puigserver, P.4    Medvedev, A.V.5    Bai, X.6    Floering, L.M.7    Spiegelman, B.M.8
  • 6
    • 17944377509 scopus 로고    scopus 로고
    • FOXC2 is a winged helix gene that counteracts obesity, hyper-triglyceridemia, and diet-induced insulin resistance
    • Cederberg A, Gronning LM, Ahren B, Tasken K, Carlsson P, Ener-back S. FOXC2 is a winged helix gene that counteracts obesity, hyper-triglyceridemia, and diet-induced insulin resistance. Cell 106: 563-573, 2001.
    • (2001) Cell , vol.106 , pp. 563-573
    • Cederberg, A.1    Gronning, L.M.2    Ahren, B.3    Tasken, K.4    Carlsson, P.5    Ener-Back, S.6
  • 9
    • 0027051199 scopus 로고
    • Occurrence of brown adipocytes in rat white adipose tissue: Molecular and morphological characterization
    • Cousin B, Cinti S, Morroni M, Raimbault S, Ricquier D, Penicaud L, Casteilla L. Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization. J. Cell Sci 103: 931-942, 1992.
    • (1992) J. Cell Sci , vol.103 , pp. 931-942
    • Cousin, B.1    Cinti, S.2    Morroni, M.3    Raimbault, S.4    Ricquier, D.5    Penicaud, L.6    Casteilla, L.7
  • 11
    • 58749091645 scopus 로고    scopus 로고
    • UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
    • Feldmann HM, Golozoubova V, Cannon B, Nedergaard J. UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab 9: 203-209, 2009.
    • (2009) Cell Metab , vol.9 , pp. 203-209
    • Feldmann, H.M.1    Golozoubova, V.2    Cannon, B.3    Nedergaard, J.4
  • 12
    • 0031011161 scopus 로고    scopus 로고
    • Appearance of brown adipocytes in white adipose tissue during CL 316,243-induced reversal of obesity and diabetes in Zucker fa/fa rats
    • Ghorbani M, Himms-Hagen J. Appearance of brown adipocytes in white adipose tissue during CL 316,243-induced reversal of obesity and diabetes in Zucker fa/fa rats. Int J Obes Relat Metab Disord 21: 465-475, 1997.
    • (1997) Int J Obes Relat Metab Disord , vol.21 , pp. 465-475
    • Ghorbani, M.1    Himms-Hagen, J.2
  • 13
    • 0032528169 scopus 로고    scopus 로고
    • Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity
    • Guerra C, Koza RA, Yamashita H, Walsh K, Kozak LP. Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. J. Clin Invest 102: 412-420, 1998.
    • (1998) J. Clin Invest , vol.102 , pp. 412-420
    • Guerra, C.1    Koza, R.A.2    Yamashita, H.3    Walsh, K.4    Kozak, L.P.5
  • 14
    • 42449097289 scopus 로고    scopus 로고
    • Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
    • Guilherme A, Virbasius JV, Puri V, Czech MP. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol 9: 367-377, 2008.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 367-377
    • Guilherme, A.1    Virbasius, J.V.2    Puri, V.3    Czech, M.P.4
  • 15
    • 35148882512 scopus 로고    scopus 로고
    • Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages
    • Hirai S, Kim YI, Goto T, Kang MS, Yoshimura M, Obata A, Yu R, Kawada T. Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Sci 81: 1272-1279, 2007.
    • (2007) Life Sci , vol.81 , pp. 1272-1279
    • Hirai, S.1    Kim, Y.I.2    Goto, T.3    Kang, M.S.4    Yoshimura, M.5    Obata, A.6    Yu, R.7    Kawada, T.8
  • 16
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature 444: 860-867, 2006.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 17
    • 80455176995 scopus 로고    scopus 로고
    • Plac8 is an inducer of C/EBPp required for brown fat differentiation, thermoregulation, and control of body weight
    • Jimenez-Preitner M, Berney X, Uldry M, Vitali A, Cinti S, Ledford JG, Thorens B. Plac8 is an inducer of C/EBPp required for brown fat differentiation, thermoregulation, and control of body weight. Cell Metab 14: 658-670, 2011.
    • (2011) Cell Metab , vol.14 , pp. 658-670
    • Jimenez-Preitner, M.1    Berney, X.2    Uldry, M.3    Vitali, A.4    Cinti, S.5    Ledford, J.G.6    Thorens, B.7
  • 18
    • 0028865142 scopus 로고
    • Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity
    • Kopecky J, Clarke G, Enerback S, Spiegelman B, Kozak LP. Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity. J. Clin Invest 96: 2914-2923, 1995.
    • (1995) J. Clin Invest , vol.96 , pp. 2914-2923
    • Kopecky, J.1    Clarke, G.2    Enerback, S.3    Spiegelman, B.4    Kozak, L.P.5
  • 22
    • 58149337340 scopus 로고    scopus 로고
    • Noradrenergic parenchy-mal nerve fiber branching after cold acclimatisation correlates with brown adipocyte density in mouse adipose organ
    • Murano I, Barbatelli G, Giordano A, Cinti S. Noradrenergic parenchy-mal nerve fiber branching after cold acclimatisation correlates with brown adipocyte density in mouse adipose organ. J Anat 214: 171-178, 2009.
    • (2009) J Anat , vol.214 , pp. 171-178
    • Murano, I.1    Barbatelli, G.2    Giordano, A.3    Cinti, S.4
  • 23
    • 77952237285 scopus 로고    scopus 로고
    • Ras signalling regulates differentiation and UCP1 expression in models of brown adipogenesis
    • Murholm M, Dixen K, Hansen JB. Ras signalling regulates differentiation and UCP1 expression in models of brown adipogenesis. Biochim Biophys Ada 1800: 619-627, 2010.
    • (2010) Biochim Biophys Ada , vol.1800 , pp. 619-627
    • Murholm, M.1    Dixen, K.2    Hansen, J.B.3
  • 24
    • 0029887455 scopus 로고    scopus 로고
    • Expression of uncoupling protein in skeletal muscle and white fat of obese mice treated with thermogenic beta 3-adrenergic agonist
    • Nagase I, Yoshida T, Kumamoto K, Umekawa T, Sakane N, Nikami H, Kawada T, Saito M. Expression of uncoupling protein in skeletal muscle and white fat of obese mice treated with thermogenic beta 3-adrenergic agonist. J. Clin Invest 97: 2898-2904, 1996.
    • (1996) J. Clin Invest , vol.97 , pp. 2898-2904
    • Nagase, I.1    Yoshida, T.2    Kumamoto, K.3    Umekawa, T.4    Sakane, N.5    Nikami, H.6    Kawada, T.7    Saito, M.8
  • 26
    • 84878629355 scopus 로고    scopus 로고
    • Avatars of adipose tissue: The saga of transformation of white fat, the villain into brown fat, the protector. Focus on Inflammation induced by RAW macrophages suppresses the UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes
    • (January 30, 2013)
    • Parinandi NL, Magalang UJ. Avatars of adipose tissue: the saga of transformation of white fat, the villain into brown fat, the protector. Focus on Inflammation induced by RAW macrophages suppresses the UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes. Am J Physiol Cell Physiol (January 30, 2013). doi:10.1152/ajpcell.00022.2013.
    • Am J Physiol Cell Physiol
    • Parinandi, N.L.1    Magalang, U.J.2
  • 27
    • 77950226740 scopus 로고    scopus 로고
    • Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes
    • Petrovic N, Walden TB, Shabalina IG, Timmons JA, Cannon B, Nedergaard J. Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. JBiol Chem 285: 7153-7164, 2010.
    • (2010) JBiol Chem , vol.285 , pp. 7153-7164
    • Petrovic, N.1    Walden, T.B.2    Shabalina, I.G.3    Timmons, J.A.4    Cannon, B.5    Nedergaard, J.6
  • 28
    • 0037024335 scopus 로고    scopus 로고
    • Differential role of PPAR gamma in the regulation of UCP-1 and adipogenesis by TNF-alpha in brown adipocytes
    • Porras A, Valladares A, Alvarez AM, Roncero C, Benito M. Differential role of PPAR gamma in the regulation of UCP-1 and adipogenesis by TNF-alpha in brown adipocytes. FEBS Lett 520: 58-62, 2002.
    • (2002) FEBS Lett , vol.520 , pp. 58-62
    • Porras, A.1    Valladares, A.2    Alvarez, A.M.3    Roncero, C.4    Benito, M.5
  • 30
    • 0018646453 scopus 로고
    • A role for brown adipose tissue in diet-induced thermogenesis
    • Rothwell NJ, Stock MJ. A role for brown adipose tissue in diet-induced thermogenesis. Nature 281: 31-35, 1979.
    • (1979) Nature , vol.281 , pp. 31-35
    • Rothwell, N.J.1    Stock, M.J.2
  • 33
    • 80051988435 scopus 로고    scopus 로고
    • An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages
    • Sakamoto T, Yamaguchi Y, Goto T, Takahashi N, Kawada T. An in vitro analysis system using a fluorescence protein reporter for evaluating anti-inflammatory effects in macrophages. Biosci Biotechnol Biochem 75: 1582-1587, 2011.
    • (2011) Biosci Biotechnol Biochem , vol.75 , pp. 1582-1587
    • Sakamoto, T.1    Yamaguchi, Y.2    Goto, T.3    Takahashi, N.4    Kawada, T.5
  • 37
    • 26244448904 scopus 로고    scopus 로고
    • A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: Role of free fatty acids and tumor necrosis factor alpha
    • Suganami T, Nishida J, Ogawa Y. A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler Thromb Vase Biol 25: 2062-2068, 2005.
    • (2005) Arterioscler Thromb Vase Biol , vol.25 , pp. 2062-2068
    • Suganami, T.1    Nishida, J.2    Ogawa, Y.3
  • 39
    • 0035937474 scopus 로고    scopus 로고
    • TNF-alpha inhibits UCP-1 expression in brown adipocytes via ERKs. Opposite effect of p38MAPK
    • Valladares A, Roncero C, Benito M, Porras A. TNF-alpha inhibits UCP-1 expression in brown adipocytes via ERKs. Opposite effect of p38MAPK. FEBS Lett 493: 6-11, 2001.
    • (2001) FEBS Lett , vol.493 , pp. 6-11
    • Valladares, A.1    Roncero, C.2    Benito, M.3    Porras, A.4
  • 43
    • 0141961773 scopus 로고    scopus 로고
    • Decreased energy levels can cause and sustain obesity
    • Wlodek D, Gonzales M. Decreased energy levels can cause and sustain obesity. J. Theor Biol 225: 33-44, 2003.
    • (2003) J. Theor Biol , vol.225 , pp. 33-44
    • Wlodek, D.1    Gonzales, M.2
  • 46
    • 0032230359 scopus 로고    scopus 로고
    • Dominant negative regulation by c-Jun of transcription of the uncoupling protein-1 gene through a proximal cAMP-regulatory element: A mechanism for repressing basal and norepinephrine-induced expression of the gene before brown adipocyte differentiation
    • Yubero P, Barbera MJ, Alvarez R, Vifias O, Mampel T, Iglesias R, Villarroya F, Giralt M. Dominant negative regulation by c-Jun of transcription of the uncoupling protein-1 gene through a proximal cAMP-regulatory element: a mechanism for repressing basal and norepinephrine-induced expression of the gene before brown adipocyte differentiation. Mol Endocrinol 12: 1023-1037, 1998.
    • (1998) Mol Endocrinol , vol.12 , pp. 1023-1037
    • Yubero, P.1    Barbera, M.J.2    Alvarez, R.3    Vifias, O.4    Mampel, T.5    Iglesias, R.6    Villarroya, F.7    Giralt, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.