Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

Nature Medicine

Volumn 18, Issue 9, 2012, Pages 1407-1412

  Talukdar, Saswata ^a,b   Oh, Da Young ^a   Bandyopadhyay, Gautam ^a   Li, Dongmei ^b   Xu, Jianfeng ^a   McNelis, Joanne ^a   Lu, Min ^a   Li, Pingping ^a   Yan, Qingyun ^b   Zhu, Yimin ^b   Ofrecio, Jachelle ^a   Lin, Michael ^a   Brenner, Martin B ^b   Olefsky, Jerrold M ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTASE; PANCREATIC ELASTASE;

ADIPOSE TISSUE CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GLUCOSE TOLERANCE; IMMUNOCOMPETENT CELL; INFLAMMATION; INSULIN RESISTANCE; INSULIN RESPONSE; INSULIN SENSITIVITY; LIPID DIET; LIVER CELL; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; WHITE ADIPOSE TISSUE; ANIMAL; BODY WEIGHT; DENSITOMETRY; DRUG EFFECT; FLOW CYTOMETRY; IMMUNOLOGY; OBESITY; REAL TIME POLYMERASE CHAIN REACTION; SECRETION (PROCESS); WESTERN BLOTTING;

MUS;

ANIMALS; BLOTTING, WESTERN; BODY WEIGHT; DENSITOMETRY; DIET, HIGH-FAT; FLOW CYTOMETRY; HEPATOCYTES; INFLAMMATION; INSULIN RESISTANCE; MICE; NEUTROPHILS; OBESITY; PANCREATIC ELASTASE; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84868671526     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2885     Document Type: Article

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