-
1
-
-
79960481458
-
The preparation of insulin
-
Best, C.H. and Scott, D.A., The preparation of insulin. J Biol Chem 1923; 57: 709-23.
-
(1923)
J Biol Chem
, vol.57
, pp. 709-723
-
-
Best, C.H.1
Scott, D.A.2
-
2
-
-
84860895192
-
Insulin's discovery: new insights on its ninetieth birthday
-
Roth, J., Qureshi, S., Whitford, I., Vranic, M., Kahn, C.R., Fantus, I.G., and Dirks, J.H., Insulin's discovery: new insights on its ninetieth birthday. Diabetes Metab Res Rev 2012; 28(4): 293-304.
-
(2012)
Diabetes Metab Res Rev
, vol.28
, Issue.4
, pp. 293-304
-
-
Roth, J.1
Qureshi, S.2
Whitford, I.3
Vranic, M.4
Kahn, C.R.5
Fantus, I.G.6
Dirks, J.H.7
-
3
-
-
84864183984
-
Observations with insulin on department of soldiers' civil re-establishment diabetics
-
Gilchrist, J.A., Best, C.H., and Banting, F.G., Observations with insulin on department of soldiers' civil re-establishment diabetics. Can Med Assoc J 1923; 13(8): 565-72.
-
(1923)
Can Med Assoc J
, vol.13
, Issue.8
, pp. 565-572
-
-
Gilchrist, J.A.1
Best, C.H.2
Banting, F.G.3
-
5
-
-
0027490682
-
Clinical pharmacology of human insulin
-
Heinemann, L. and Richter, B., Clinical pharmacology of human insulin. Diabetes Care 1993; 16 Suppl 3: 90-100.
-
(1993)
Diabetes Care
, vol.16
, Issue.3
, pp. 90-100
-
-
Heinemann, L.1
Richter, B.2
-
6
-
-
37349114891
-
Process and purification for manufacture of a modified insulin intended for oral delivery
-
Dave, N., Hazra, P., Khedkar, A., Manjunath, H.S., Iyer, H., and Suryanarayanan, S., Process and purification for manufacture of a modified insulin intended for oral delivery. J Chromatogr A 2008; 1177(2): 282-6.
-
(2008)
J Chromatogr A
, vol.1177
, Issue.2
, pp. 282-286
-
-
Dave, N.1
Hazra, P.2
Khedkar, A.3
Manjunath, H.S.4
Iyer, H.5
Suryanarayanan, S.6
-
7
-
-
68349110805
-
Obesity, inflammation, and insulin resistance-a mini-review
-
Zeyda, M. and Stulnig, T.M., Obesity, inflammation, and insulin resistance-a mini-review. Gerontology 2009; 55(4): 379-86.
-
(2009)
Gerontology
, vol.55
, Issue.4
, pp. 379-386
-
-
Zeyda, M.1
Stulnig, T.M.2
-
8
-
-
62749172933
-
Insulin resistance and steatosis in humans
-
Capeau, J., Insulin resistance and steatosis in humans. Diabetes Metab 2008; 34(6 Pt 2): 649-57.
-
(2008)
Diabetes Metab
, vol.34
, Issue.2-6
, pp. 649-657
-
-
Capeau, J.1
-
9
-
-
77955427566
-
IGF-IEc expression, regulation and biological function in different tissues
-
Dai, Z., Wu, F., Yeung, E.W., and Li, Y., IGF-IEc expression, regulation and biological function in different tissues. Growth Horm IGF Res 2010; 20(4): 275-81.
-
(2010)
Growth Horm IGF Res
, vol.20
, Issue.4
, pp. 275-281
-
-
Dai, Z.1
Wu, F.2
Yeung, E.W.3
Li, Y.4
-
10
-
-
77149130495
-
Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration
-
Matheny, R.W., Jr., Nindl, B.C., and Adamo, M.L., Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration. Endocrinology 2010; 151(3): 865-75.
-
(2010)
Endocrinology
, vol.151
, Issue.3
, pp. 865-875
-
-
Matheny, R.W.Jr.1
Nindl, B.C.2
Adamo, M.L.3
-
11
-
-
84861977131
-
Insulin-like growth factors in the gastrointestinal tract and liver
-
Kuemmerle, J.F., Insulin-like growth factors in the gastrointestinal tract and liver. Endocrinol Metab Clin North Am 2012; 41(2): 409-23, vii.
-
(2012)
Endocrinol Metab Clin North Am
, vol.41
, Issue.2
-
-
Kuemmerle, J.F.1
-
12
-
-
15244350991
-
Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease
-
de la Monte, S.M. andWands, J.R., Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease. J Alzheimer's Dis 2005; 7(1): 45-61.
-
(2005)
J Alzheimer's Dis
, vol.7
, Issue.1
, pp. 45-61
-
-
de la Monte, S.M.1
Wands, J.R.2
-
13
-
-
57349130542
-
Expanding the mind: insulin-like growth factor I and brain development
-
D'Ercole, A.J. and Ye, P., Expanding the mind: insulin-like growth factor I and brain development. Endocrinology 2008; 149(12): 5958-62.
-
(2008)
Endocrinology
, vol.149
, Issue.12
, pp. 5958-5962
-
-
D'Ercole, A.J.1
Ye, P.2
-
14
-
-
67149139990
-
Schilbach, K., and Schubert, M., The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of Alzheimer's disease: from model organisms to human disease
-
Freude, S., Schilbach, K., and Schubert, M., The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of Alzheimer's disease: from model organisms to human disease. Curr Alzheimer Res 2009; 6(3): 213-23.
-
(2009)
Curr Alzheimer Res
, vol.6
, Issue.3
, pp. 213-223
-
-
Freude, S.1
-
15
-
-
33846962851
-
Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination
-
Zeger, M., Popken, G., Zhang, J., Xuan, S., Lu, Q.R., Schwab, M.H., Nave, K.A., Rowitch, D., D'Ercole, A.J., and Ye, P., Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination. Glia 2007; 55(4): 400-11.
-
(2007)
Glia
, vol.55
, Issue.4
, pp. 400-411
-
-
Zeger, M.1
Popken, G.2
Zhang, J.3
Xuan, S.4
Lu, Q.R.5
Schwab, M.H.6
Nave, K.A.7
Rowitch, D.8
D'Ercole, A.J.9
Ye, P.10
-
16
-
-
68249128179
-
The liver-brain axis of alcoholmediated neurodegeneration: role of toxic lipids
-
de la Monte, S.M., Longato, L., Tong, M., DeNucci, S., and Wands, J.R., The liver-brain axis of alcoholmediated neurodegeneration: role of toxic lipids. Int J Environ Res Public Health 2009; 6(7): 2055-75.
-
(2009)
Int J Environ Res Public Health
, vol.6
, Issue.7
, pp. 2055-2075
-
-
de la Monte, S.M.1
Longato, L.2
Tong, M.3
DeNucci, S.4
Wands, J.R.5
-
17
-
-
70349744089
-
Insulin resistance and neurodegeneration: roles of obesity, type 2 diabetes mellitus and nonalcoholic steatohepatitis
-
de la Monte, S.M., Longato, L., Tong, M., andWands, J.R., Insulin resistance and neurodegeneration: roles of obesity, type 2 diabetes mellitus and nonalcoholic steatohepatitis. Curr Opin Investig Drugs 2009; 10(10): 1049-60.
-
(2009)
Curr Opin Investig Drugs
, vol.10
, Issue.10
, pp. 1049-1060
-
-
de la Monte, S.M.1
Longato, L.2
Tong, M.3
Wands, J.R.4
-
18
-
-
77649195357
-
Molecular evolution and functional characterization of Drosophila insulin-like peptides
-
Gronke, S., Clarke, D.F., Broughton, S., Andrews, T.D., and Partridge, L., Molecular evolution and functional characterization of Drosophila insulin-like peptides. PLoS Genet 2010; 6(2): e1000857.
-
(2010)
PLoS Genet
, vol.6
, Issue.2
, pp. 1000857
-
-
Gronke, S.1
Clarke, D.F.2
Broughton, S.3
Andrews, T.D.4
Partridge, L.5
-
19
-
-
42449134942
-
Cross talk between the insulin and Wnt signaling pathways: evidence from intestinal endocrine L cells
-
Yi, F., Sun, J., Lim, G.E., Fantus, I.G., Brubaker, P.L., and Jin, T., Cross talk between the insulin and Wnt signaling pathways: evidence from intestinal endocrine L cells. Endocrinology 2008; 149(5): 2341-51.
-
(2008)
Endocrinology
, vol.149
, Issue.5
, pp. 2341-2351
-
-
Yi, F.1
Sun, J.2
Lim, G.E.3
Fantus, I.G.4
Brubaker, P.L.5
Jin, T.6
-
20
-
-
77953233022
-
Cross-regulation of signaling pathways: an example of nuclear hormone receptors and the canonical Wnt pathway
-
Beildeck, M.E., Gelmann, E.P., and Byers, S.W., Cross-regulation of signaling pathways: an example of nuclear hormone receptors and the canonical Wnt pathway. Experimental cell research 2010; 316(11): 1763-72.
-
(2010)
Experimental cell research
, vol.316
, Issue.11
, pp. 1763-1772
-
-
Beildeck, M.E.1
Gelmann, E.P.2
Byers, S.W.3
-
21
-
-
0348134529
-
Alzheimer's disease linking neurodegeneration with neurodevelopment
-
Grilli, M., Ferrari Toninelli, G., Uberti, D., Spano, P., and Memo, M., Alzheimer's disease linking neurodegeneration with neurodevelopment. Funct Neurol 2003; 18(3): 145-8.
-
(2003)
Funct Neurol
, vol.18
, Issue.3
, pp. 145-148
-
-
Grilli, M.1
Ferrari Toninelli, G.2
Uberti, D.3
Spano, P.4
Memo, M.5
-
22
-
-
3142512452
-
Potential role of presenilinregulated signaling pathways in sporadic neurodegeneration
-
Koo, E.H. and Kopan, R., Potential role of presenilinregulated signaling pathways in sporadic neurodegeneration. Nat Med 2004; 10 Suppl: S26-33.
-
(2004)
Nat Med
, vol.10
, pp. 26-33
-
-
Koo, E.H.1
Kopan, R.2
-
23
-
-
0034084768
-
Roles of Wnt proteins in neural development and maintenance
-
Patapoutian, A. and Reichardt, L.F., Roles of Wnt proteins in neural development and maintenance. Current opinion in neurobiology 2000; 10(3): 392-9.
-
(2000)
Current opinion in neurobiology
, vol.10
, Issue.3
, pp. 392-399
-
-
Patapoutian, A.1
Reichardt, L.F.2
-
24
-
-
0033950382
-
Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1
-
Galceran, J., Miyashita-Lin, E.M., Devaney, E., Rubenstein, J.L., and Grosschedl, R., Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development 2000; 127(3): 469-82.
-
(2000)
Development
, vol.127
, Issue.3
, pp. 469-482
-
-
Galceran, J.1
Miyashita-Lin, E.M.2
Devaney, E.3
Rubenstein, J.L.4
Grosschedl, R.5
-
25
-
-
0031591946
-
Wnt signalling required for expansion of neural crest and CNS progenitors
-
Ikeya, M., Lee, S.M., Johnson, J.E., McMahon, A.P., and Takada, S., Wnt signalling required for expansion of neural crest and CNS progenitors. Nature 1997; 389(6654): 966-70.
-
(1997)
Nature
, vol.389
, Issue.6654
, pp. 966-970
-
-
Ikeya, M.1
Lee, S.M.2
Johnson, J.E.3
McMahon, A.P.4
Takada, S.5
-
26
-
-
23444456469
-
Maintenance of Wnt-3 expression in Purkinje cells of the mouse cerebellum depends on interactions with granule cells
-
Salinas, P.C., Fletcher, C., Copeland, N.G., Jenkins, N.A., and Nusse, R., Maintenance of Wnt-3 expression in Purkinje cells of the mouse cerebellum depends on interactions with granule cells. Development 1994; 120(5): 1277-86.
-
(1994)
Development
, vol.120
, Issue.5
, pp. 1277-1286
-
-
Salinas, P.C.1
Fletcher, C.2
Copeland, N.G.3
Jenkins, N.A.4
Nusse, R.5
-
27
-
-
77954210220
-
An updated overview on Wnt signaling pathways: a prelude for more
-
Rao, T.P. and Kuhl, M., An updated overview on Wnt signaling pathways: a prelude for more. Circulation research 2010; 106(12): 1798-806.
-
(2010)
Circulation research
, vol.106
, Issue.12
, pp. 1798-1806
-
-
Rao, T.P.1
Kuhl, M.2
-
28
-
-
79957597367
-
Structural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1)
-
Tanneberger, K., Pfister, A.S., Kriz, V., Bryja, V., Schambony, A., and Behrens, J., Structural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1). The Journal of biological chemistry 2011; 286(22): 19204-14.
-
(2011)
The Journal of biological chemistry
, vol.286
, Issue.22
, pp. 19204-14
-
-
Tanneberger, K.1
Pfister, A.S.2
Kriz, V.3
Bryja, V.4
Schambony, A.5
Behrens, J.6
-
29
-
-
79957597124
-
Deconstructing the sscatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling
-
Roberts, D.M., Pronobis, M.I., Poulton, J.S., Waldmann, J.D., Stephenson, E.M., Hanna, S., and Peifer, M., Deconstructing the sscatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling. Molecular biology of the cell 2011; 22(11): 1845-63.
-
(2011)
Molecular biology of the cell
, vol.22
, Issue.11
, pp. 1845-1863
-
-
Roberts, D.M.1
Pronobis, M.I.2
Poulton, J.S.3
Waldmann, J.D.4
Stephenson, E.M.5
Hanna, S.6
Peifer, M.7
-
30
-
-
67650230896
-
Wnt/betacatenin signaling: components, mechanisms, and diseases
-
MacDonald, B.T., Tamai, K., and He, X., Wnt/betacatenin signaling: components, mechanisms, and diseases. Developmental cell 2009; 17(1): 9-26.
-
(2009)
Developmental cell
, vol.17
, Issue.1
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
31
-
-
78650722531
-
Aspartyl-(asparaginyl) betahydroxylase, hypoxia-inducible factor-alpha and Notch cross-talk in regulating neuronal motility
-
Lawton, M., Tong, M., Gundogan, F., Wands, J.R., and de la Monte, S.M., Aspartyl-(asparaginyl) betahydroxylase, hypoxia-inducible factor-alpha and Notch cross-talk in regulating neuronal motility. Oxidative medicine and cellular longevity 2010; 3(5): 347-56.
-
(2010)
Oxidative medicine and cellular longevity
, vol.3
, Issue.5
, pp. 347-356
-
-
Lawton, M.1
Tong, M.2
Gundogan, F.3
Wands, J.R.4
de la Monte, S.M.5
-
32
-
-
41149159084
-
Insulin resistance and hyperinsulinemia: is hyperinsulinemia the cart or the horse?
-
Shanik, M.H., Xu,Y., Skrha, J., Dankner, R., Zick,Y., and Roth, J., Insulin resistance and hyperinsulinemia: is hyperinsulinemia the cart or the horse? Diabetes care 2008; 31 Suppl 2: S262-8.
-
(2008)
Diabetes care
, vol.31
, Issue.2
, pp. 262-268
-
-
Shanik, M.H.1
Xu, Y.2
Skrha, J.3
Dankner, R.4
Zick, Y.5
Roth, J.6
-
33
-
-
68149091969
-
Basal-state hyperinsulinemia in healthy normoglycemic adults is predictive of type 2 diabetes over a 24-year follow-up: a preliminary report
-
Dankner, R., Chetrit, A., Shanik, M.H., Raz, I., and Roth, J., Basal-state hyperinsulinemia in healthy normoglycemic adults is predictive of type 2 diabetes over a 24-year follow-up: a preliminary report. Diabetes care 2009; 32(8): 1464-6.
-
(2009)
Diabetes care
, vol.32
, Issue.8
, pp. 1464-1466
-
-
Dankner, R.1
Chetrit, A.2
Shanik, M.H.3
Raz, I.4
Roth, J.5
-
34
-
-
79952819314
-
Hyperinsulinemia is a predictor of new cardiovascular events in Colombian patients with a first myocardial infarction
-
Garcia, R.G., Rincon, M.Y., Arenas, W.D., Silva, S.Y., Reyes, L.M., Ruiz, S.L., Ramirez, F., Camacho, P.A., Luengas, C., Saaibi, J.F., Balestrini, S., Morillo, C., and Lopez-Jaramillo, P., Hyperinsulinemia is a predictor of new cardiovascular events in Colombian patients with a first myocardial infarction. Int J Cardiol 2011; 148(1): 85-90.
-
(2011)
Int J Cardiol
, vol.148
, Issue.1
, pp. 85-90
-
-
Garcia, R.G.1
Rincon, M.Y.2
Arenas, W.D.3
Silva, S.Y.4
Reyes, L.M.5
Ruiz, S.L.6
Ramirez, F.7
Camacho, P.A.8
Luengas, C.9
Saaibi, J.F.10
Balestrini, S.11
Morillo, C.12
Lopez-Jaramillo, P.13
-
35
-
-
67649772141
-
The adverse prognostic significance of the metabolic syndrome with and without hypertension in patients who underwent complete coronary revascularization
-
Kasai, T., Miyauchi, K., Kajimoto, K., Kubota, N., Dohi, T., Kurata, T., Amano, A., and Daida, H., The adverse prognostic significance of the metabolic syndrome with and without hypertension in patients who underwent complete coronary revascularization. J Hypertens 2009; 27(5): 1017-24.
-
(2009)
J Hypertens
, vol.27
, Issue.5
, pp. 1017-1024
-
-
Kasai, T.1
Miyauchi, K.2
Kajimoto, K.3
Kubota, N.4
Dohi, T.5
Kurata, T.6
Amano, A.7
Daida, H.8
-
36
-
-
72749108254
-
Metabolic syndrome and postmenopausal breast cancer in the ORDET cohort: a nested case-control study
-
Agnoli, C., Berrino, F., Abagnato, C.A., Muti, P., Panico, S., Crosignani, P., and Krogh, V., Metabolic syndrome and postmenopausal breast cancer in the ORDET cohort: a nested case-control study. Nutr Metab Cardiovasc Dis 2010; 20(1): 41-8.
-
(2010)
Nutr Metab Cardiovasc Dis
, vol.20
, Issue.1
, pp. 41-48
-
-
Agnoli, C.1
Berrino, F.2
Abagnato, C.A.3
Muti, P.4
Panico, S.5
Crosignani, P.6
Krogh, V.7
-
37
-
-
85027950107
-
Metabolic diseases and cancer risk
-
Faulds, M.H. and Dahlman-Wright, K., Metabolic diseases and cancer risk. Curr Opin Oncol 2012; 24(1): 58-61.
-
(2012)
Curr Opin Oncol
, vol.24
, Issue.1
, pp. 58-61
-
-
Faulds, M.H.1
Dahlman-Wright, K.2
-
38
-
-
84856220772
-
A retrospective review of the metabolic syndrome in women diagnosed with breast cancer and correlation with estrogen receptor
-
Colonna, S.V., Douglas Case, L., and Lawrence, J.A., A retrospective review of the metabolic syndrome in women diagnosed with breast cancer and correlation with estrogen receptor. Breast Cancer Res Treat 2012; 131(1): 325-31.
-
(2012)
Breast Cancer Res Treat
, vol.131
, Issue.1
, pp. 325-331
-
-
Colonna, S.V.1
Douglas Case, L.2
Lawrence, J.A.3
-
39
-
-
67849085394
-
Epidemiological Trends Strongly Suggest Exposures as Etiologic Agents in the Pathogenesis of Sporadic Alzheimer's Disease, Diabetes Mellitus, and Non-Alcoholic Steatohepatitis
-
de la Monte, S.M., Neusner, A., Chu, J., and Lawton, M., Epidemiological Trends Strongly Suggest Exposures as Etiologic Agents in the Pathogenesis of Sporadic Alzheimer's Disease, Diabetes Mellitus, and Non-Alcoholic Steatohepatitis. J Alzheimer's Dis 2009.
-
(2009)
J Alzheimer's Dis
-
-
de la Monte, S.M.1
Neusner, A.2
Chu, J.3
Lawton, M.4
-
40
-
-
0002342654
-
Definitions and diagnostic criteria
-
Third ed. Clinical diagnosis and management of Alzheimer's disease. ed. S.Gauthier , London: Informa UK Limited
-
Cummings, J.L., Definitions and diagnostic criteria. Third ed. Clinical diagnosis and management of Alzheimer's disease. ed. S.Gauthier 2007, London: Informa UK Limited.
-
(2007)
-
-
Cummings, J.L.1
-
41
-
-
77951683939
-
Biomarkers in Alzheimer's disease: past, present and future
-
Gustaw-Rothenberg, K., Lerner, A., Bonda, D.J., Lee, H.G., Zhu, X., Perry, G., and Smith, M.A., Biomarkers in Alzheimer's disease: past, present and future. Biomark Med 2010; 4(1): 15-26.
-
(2010)
Biomark Med
, vol.4
, Issue.1
, pp. 15-26
-
-
Gustaw-Rothenberg, K.1
Lerner, A.2
Bonda, D.J.3
Lee, H.G.4
Zhu, X.5
Perry, G.6
Smith, M.A.7
-
42
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal longterm potentiation in vivo
-
Walsh, D.M., Klyubin, I., Fadeeva, J.V., Cullen, W.K., Anwyl, R., Wolfe, M.S., Rowan, M.J., and Selkoe, D.J., Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal longterm potentiation in vivo. Nature 2002; 416(6880): 535-9.
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
43
-
-
15444339756
-
Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease
-
Frolich, L., Blum-Degen, D., Bernstein, H.G., Engelsberger, S., Humrich, J., Laufer, S., Muschner, D., Thalheimer, A., Turk, A., Hoyer, S., Zochling, R., Boissl, K.W., Jellinger, K., and Riederer, P., Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease. J Neural Transm 1998; 105(4-5): 423-38.
-
(1998)
J Neural Transm
, vol.105
, Issue.4-5
, pp. 423-438
-
-
Frolich, L.1
Blum-Degen, D.2
Bernstein, H.G.3
Engelsberger, S.4
Humrich, J.5
Laufer, S.6
Muschner, D.7
Thalheimer, A.8
Turk, A.9
Hoyer, S.10
Zochling, R.11
Boissl, K.W.12
Jellinger, K.13
Riederer, P.14
-
44
-
-
1842785179
-
Glucose metabolism and insulin receptor signal transduction in Alzheimer's disease
-
Hoyer, S., Glucose metabolism and insulin receptor signal transduction in Alzheimer's disease. Eur J Pharmacol 2004; 490(1-3): 115-25.
-
(2004)
Eur J Pharmacol
, vol.490
, Issue.1-3
, pp. 115-125
-
-
Hoyer, S.1
-
45
-
-
33644591150
-
Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine
-
Rivera, E.J., Goldin, A., Fulmer, N., Tavares, R., Wands, J.R., and de la Monte, S.M., Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine. J Alzheimer's Dis 2005; 8(3): 247-68.
-
(2005)
J Alzheimer's Dis
, vol.8
, Issue.3
, pp. 247-268
-
-
Rivera, E.J.1
Goldin, A.2
Fulmer, N.3
Tavares, R.4
Wands, J.R.5
de la Monte, S.M.6
-
46
-
-
15244351255
-
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes?
-
Steen, E., Terry, B.M., Rivera, E.J., Cannon, J.L., Neely, T.R., Tavares, R., Xu, X.J., Wands, J.R., and de la Monte, S.M., Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes? J Alzheimer's Dis 2005; 7(1): 63-80.
-
(2005)
J Alzheimer's Dis
, vol.7
, Issue.1
, pp. 63-80
-
-
Steen, E.1
Terry, B.M.2
Rivera, E.J.3
Cannon, J.L.4
Neely, T.R.5
Tavares, R.6
Xu, X.J.7
Wands, J.R.8
de la Monte, S.M.9
-
47
-
-
84856606017
-
Therapeutic targets of brain insulin resistance in sporadic Alzheimer's disease
-
de la Monte, S.M., Therapeutic targets of brain insulin resistance in sporadic Alzheimer's disease. Frontiers in bioscience: a journal and virtual library 2012; E4: 1582-605.
-
(2012)
Frontiers in bioscience: a journal and virtual library
, vol.4
, pp. 1582-1605
-
-
de la Monte, S.M.1
-
48
-
-
84862892661
-
Dysfunctional pro-ceramide, ER stress, and insulin/IGF signaling networks with progression of Alzheimer's disease
-
de la Monte, S.M., Re, E., Longato, L., and Tong, M., Dysfunctional pro-ceramide, ER stress, and insulin/IGF signaling networks with progression of Alzheimer's disease. J Alzheimer's Dis 2012; 30(0): S217-29.
-
(2012)
J Alzheimer's Dis
, vol.30
, pp. S217-S229
-
-
de la Monte, S.M.1
Re, E.2
Longato, L.3
Tong, M.4
-
49
-
-
51649088252
-
Correlating cerebral hypometabolism with future memory decline in subsequent converters to amnestic pre-mild cognitive impairment
-
Caselli, R.J., Chen, K., Lee,W., Alexander, G.E., and Reiman, E.M., Correlating cerebral hypometabolism with future memory decline in subsequent converters to amnestic pre-mild cognitive impairment. Arch Neurol 2008; 65(9): 1231-6.
-
(2008)
Arch Neurol
, vol.65
, Issue.9
, pp. 1231-1236
-
-
Caselli, R.J.1
Chen, K.2
Lee, W.3
Alexander, G.E.4
Reiman, E.M.5
-
50
-
-
57649187117
-
Brain glucose hypometabolism and oxidative stress in preclinical Alzheimer's disease
-
Mosconi, L., Pupi, A., and De Leon, M.J., Brain glucose hypometabolism and oxidative stress in preclinical Alzheimer's disease. Ann N Y Acad Sci 2008; 1147: 180-95.
-
(2008)
Ann N Y Acad Sci
, vol.1147
, pp. 180-195
-
-
Mosconi, L.1
Pupi, A.2
De Leon, M.J.3
-
51
-
-
77950878145
-
Hypometabolism in Alzheimer-affected brain regions in cognitively healthy Latino individuals carrying the apolipoprotein E epsilon4 allele
-
Langbaum, J.B., Chen, K., Caselli, R.J., Lee, W., Reschke, C., Bandy, D., Alexander, G.E., Burns, C.M., Kaszniak, A.W., Reeder, S.A., Corneveaux, J.J., Allen, A.N., Pruzin, J., Huentelman, M.J., Fleisher, A.S., and Reiman, E.M., Hypometabolism in Alzheimer-affected brain regions in cognitively healthy Latino individuals carrying the apolipoprotein E epsilon4 allele. Arch Neurol 2010; 67(4): 462-8.
-
(2010)
Arch Neurol
, vol.67
, Issue.4
, pp. 462-468
-
-
Langbaum, J.B.1
Chen, K.2
Caselli, R.J.3
Lee, W.4
Reschke, C.5
Bandy, D.6
Alexander, G.E.7
Burns, C.M.8
Kaszniak, A.W.9
Reeder, S.A.10
Corneveaux, J.J.11
Allen, A.N.12
Pruzin, J.13
Huentelman, M.J.14
Fleisher, A.S.15
Reiman, E.M.16
-
52
-
-
0024545260
-
Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type
-
Hoyer, S. and Nitsch, R., Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type. J Neural Transm 1989; 75(3): 227-32.
-
(1989)
J Neural Transm
, vol.75
, Issue.3
, pp. 227-232
-
-
Hoyer, S.1
Nitsch, R.2
-
53
-
-
0025856239
-
Predominant abnormality in cerebral glucose utilization in late-onset dementia of the Alzheimer type: a crosssectional comparison against advanced late-onset and incipient early-onset cases
-
Hoyer, S., Nitsch, R., and Oesterreich, K., Predominant abnormality in cerebral glucose utilization in late-onset dementia of the Alzheimer type: a crosssectional comparison against advanced late-onset and incipient early-onset cases. J Neural Transm Park Dis Dement Sect 1991; 3(1): 1-14.
-
(1991)
J Neural Transm Park Dis Dement Sect
, vol.3
, Issue.1
, pp. 1-14
-
-
Hoyer, S.1
Nitsch, R.2
Oesterreich, K.3
-
54
-
-
84859718265
-
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
-
Talbot, K., Wang, H.Y., Kazi, H., Han, L.Y., Bakshi, K.P., Stucky, A., Fuino, R.L., Kawaguchi, K.R., Samoyedny, A.J., Wilson, R.S., Arvanitakis, Z., Schneider, J.A., Wolf, B.A., Bennett, D.A., Trojanowski, J.Q., and Arnold, S.E., Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. J Clin Invest 2012; 122(4): 1316-38.
-
(2012)
J Clin Invest
, vol.122
, Issue.4
, pp. 1316-1338
-
-
Talbot, K.1
Wang, H.Y.2
Kazi, H.3
Han, L.Y.4
Bakshi, K.P.5
Stucky, A.6
Fuino, R.L.7
Kawaguchi, K.R.8
Samoyedny, A.J.9
Wilson, R.S.10
Arvanitakis, Z.11
Schneider, J.A.12
Wolf, B.A.13
Bennett, D.A.14
Trojanowski, J.Q.15
Arnold, S.E.16
-
55
-
-
33645960672
-
Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease
-
Lester-Coll, N., Rivera, E.J., Soscia, S.J., Doiron, K., Wands, J.R., and de la Monte, S.M., Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease. J Alzheimer's Dis 2006; 9(1): 13-33.
-
(2006)
J Alzheimer's Dis
, vol.9
, Issue.1
, pp. 13-33
-
-
Lester-Coll, N.1
Rivera, E.J.2
Soscia, S.J.3
Doiron, K.4
Wands, J.R.5
de la Monte, S.M.6
-
56
-
-
1542343843
-
Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity
-
Weinstock, M. and Shoham, S., Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity. J Neural Transm 2004; 111(3): 347-66.
-
(2004)
J Neural Transm
, vol.111
, Issue.3
, pp. 347-366
-
-
Weinstock, M.1
Shoham, S.2
-
57
-
-
0036898999
-
Genotoxicity of streptozotocin
-
Bolzan, A.D. and Bianchi, M.S., Genotoxicity of streptozotocin. Mutat Res 2002; 512(2-3): 121-34.
-
(2002)
Mutat Res
, vol.512
, Issue.2-3
, pp. 121-134
-
-
Bolzan, A.D.1
Bianchi, M.S.2
-
58
-
-
0037355040
-
The effect of low versus high dose of streptozotocin in cynomolgus monkeys (Macaca fascilularis)
-
Koulmanda, M., Qipo, A., Chebrolu, S., O'Neil, J., Auchincloss, H., and Smith, R.N., The effect of low versus high dose of streptozotocin in cynomolgus monkeys (Macaca fascilularis). Am J Transplant 2003; 3(3): 267-72.
-
(2003)
Am J Transplant
, vol.3
, Issue.3
, pp. 267-272
-
-
Koulmanda, M.1
Qipo, A.2
Chebrolu, S.3
O'Neil, J.4
Auchincloss, H.5
Smith, R.N.6
-
59
-
-
79953088080
-
si-RNA inhibition of brain insulin or insulin-like growth factor receptors causes developmental cerebellar abnormalities: relevance to fetal alcohol spectrum disorder
-
de la Monte, S.M., Tong, M., Bowling, N., and Moskal, P., si-RNA inhibition of brain insulin or insulin-like growth factor receptors causes developmental cerebellar abnormalities: relevance to fetal alcohol spectrum disorder. Molecular brain 2011; 4: 13.
-
(2011)
Molecular brain
, vol.4
, pp. 13
-
-
de la Monte, S.M.1
Tong, M.2
Bowling, N.3
Moskal, P.4
-
60
-
-
84862748768
-
Neuroprotective and neurotrophic actions of glucagonlike peptide-1: an emerging opportunity to treat neurodegenerative and cerebrovascular disorders
-
Salcedo, I., Tweedie, D., Li,Y., and Greig, N.H., Neuroprotective and neurotrophic actions of glucagonlike peptide-1: an emerging opportunity to treat neurodegenerative and cerebrovascular disorders. Br J Pharmacol 2012; 166(5): 1586-99.
-
(2012)
Br J Pharmacol
, vol.166
, Issue.5
, pp. 1586-1599
-
-
Salcedo, I.1
Tweedie, D.2
Li, Y.3
Greig, N.H.4
-
61
-
-
78751702337
-
IGF-I and the aging mammalian brain
-
Piriz, J., Muller, A., Trejo, J.L., and Torres-Aleman, I., IGF-I and the aging mammalian brain. Exp Gerontol 2011; 46(2-3): 96-9.
-
(2011)
Exp Gerontol
, vol.46
, Issue.2-3
, pp. 96-99
-
-
Piriz, J.1
Muller, A.2
Trejo, J.L.3
Torres-Aleman, I.4
-
62
-
-
79957877029
-
The impact of dietary energy intake on cognitive aging
-
Mattson, M.P., The impact of dietary energy intake on cognitive aging. Front Aging Neurosci 2010; 2: 5.
-
(2010)
Front Aging Neurosci
, vol.2
, pp. 5
-
-
Mattson, M.P.1
-
63
-
-
12144290448
-
Role for neuronal insulin resistance in neurodegenerative diseases
-
Schubert, M., Gautam, D., Surjo, D., Ueki, K., Baudler, S., Schubert, D., Kondo, T., Alber, J., Galldiks, N.,Kustermann, E., Arndt, S., Jacobs, A.H., Krone, W., Kahn, C.R., and Bruning, J.C., Role for neuronal insulin resistance in neurodegenerative diseases. Proc Natl Acad Sci U S A 2004; 101(9): 3100-5.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.9
, pp. 3100-3105
-
-
Schubert, M.1
Gautam, D.2
Surjo, D.3
Ueki, K.4
Baudler, S.5
Schubert, D.6
Kondo, T.7
Alber, J.8
Galldiks N.Kustermann, E.9
Arndt, S.10
Jacobs, A.H.11
Krone, W.12
Kahn, C.R.13
Bruning, J.C.14
-
64
-
-
67349143998
-
Classification and basic pathology of Alzheimer disease
-
Duyckaerts, C., Delatour, B., and Potier, M.C., Classification and basic pathology of Alzheimer disease. Acta Neuropathol 2009; 118(1): 5-36.
-
(2009)
Acta Neuropathol
, vol.118
, Issue.1
, pp. 5-36
-
-
Duyckaerts, C.1
Delatour, B.2
Potier, M.C.3
-
65
-
-
0035232145
-
Presenilin function: connections to Alzheimer's disease and signal transduction
-
Fraser, P.E., Yu, G., Levesque, L., Nishimura, M., Yang, D.S., Mount, H.T., Westaway, D., and St George-Hyslop, P.H., Presenilin function: connections to Alzheimer's disease and signal transduction. Biochem Soc Symp 2001(67): 89-100.
-
(2001)
Biochem Soc Symp
, vol.67
, pp. 89-100
-
-
Fraser, P.E.1
Yu, G.2
Levesque, L.3
Nishimura, M.4
Yang, D.S.5
Mount, H.T.6
Westaway, D.7
St George-Hyslop, P.H.8
-
66
-
-
76949087724
-
Neuroimmunomodulation in the pathogenesis of Alzheimer's disease
-
Morales, I., Farias, G., and Maccioni, R.B., Neuroimmunomodulation in the pathogenesis of Alzheimer's disease. Neuroimmunomodulation 2010; 17(3): 202-4.
-
(2010)
Neuroimmunomodulation
, vol.17
, Issue.3
, pp. 202-204
-
-
Morales, I.1
Farias, G.2
Maccioni, R.B.3
-
67
-
-
67349142329
-
Mechanisms of tau-induced neurodegeneration
-
Iqbal, K., Liu, F., Gong, C.X., Alonso Adel, C., and Grundke-Iqbal, I., Mechanisms of tau-induced neurodegeneration. Acta Neuropathol 2009; 118(1): 53-69.
-
(2009)
Acta Neuropathol
, vol.118
, Issue.1
, pp. 53-69
-
-
Iqbal, K.1
Liu, F.2
Gong, C.X.3
Alonso Adel, C.4
Grundke-Iqbal, I.5
-
68
-
-
0242664588
-
Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418
-
Bhat, R., Xue, Y., Berg, S., Hellberg, S., Ormo, M., Nilsson, Y., Radesater, A.C., Jerning, E., Markgren, P.O., Borgegard, T., Nylof, M., Gimenez-Cassina, A., Hernandez, F., Lucas, J.J., Diaz-Nido, J., andAvila, J., Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J Biol Chem 2003; 278(46): 45937-45.
-
(2003)
J Biol Chem
, vol.278
, Issue.46
, pp. 45937-45
-
-
Bhat, R.1
Xue, Y.2
Berg, S.3
Hellberg, S.4
Ormo, M.5
Nilsson, Y.6
Radesater, A.C.7
Jerning, E.8
Markgren, P.O.9
Borgegard, T.10
Nylof, M.11
Gimenez-Cassina, A.12
Hernandez, F.13
Lucas, J.J.14
Diaz-Nido, J.15
Avila, J.16
-
69
-
-
77957010408
-
Drug development for tauopathy and Alzheimer's disease
-
Takashima, A., [Drug development for tauopathy and Alzheimer's disease]. Nihon Shinkei Seishin Yakurigaku Zasshi 2010; 30(4): 177-80.
-
(2010)
Nihon Shinkei Seishin Yakurigaku Zasshi
, vol.30
, Issue.4
, pp. 177-180
-
-
Takashima, A.1
-
70
-
-
33845954777
-
It may take inflammation, phosphorylation and ubiquitination to 'tangle' in Alzheimer's disease
-
Arnaud, L., Robakis, N.K., and Figueiredo-Pereira, M.E., It may take inflammation, phosphorylation and ubiquitination to 'tangle' in Alzheimer's disease. Neurodegener Dis 2006; 3(6): 313-9.
-
(2006)
Neurodegener Dis
, vol.3
, Issue.6
, pp. 313-319
-
-
Arnaud, L.1
Robakis, N.K.2
Figueiredo-Pereira, M.E.3
-
71
-
-
42349089604
-
The ubiquitin-proteasome system in Alzheimer's disease
-
Oddo, S., The ubiquitin-proteasome system in Alzheimer's disease. J Cell Mol Med 2008; 12(2): 363-73.
-
(2008)
J Cell Mol Med
, vol.12
, Issue.2
, pp. 363-373
-
-
Oddo, S.1
-
72
-
-
0345276565
-
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
-
Mandelkow, E.M., Stamer, K., Vogel, R., Thies, E., and Mandelkow, E., Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol Aging 2003; 24(8): 1079-85.
-
(2003)
Neurobiol Aging
, vol.24
, Issue.8
, pp. 1079-1085
-
-
Mandelkow, E.M.1
Stamer, K.2
Vogel, R.3
Thies, E.4
Mandelkow, E.5
-
73
-
-
0036282840
-
Chronic gestational exposure to ethanol impairs insulin-stimulated survival and mitochondrial function in cerebellar neurons
-
de la Monte, S.M. and Wands, J.R., Chronic gestational exposure to ethanol impairs insulin-stimulated survival and mitochondrial function in cerebellar neurons. CMLS, Cell Mol Life Sci 2002; 59: 882-893.
-
(2002)
CMLS, Cell Mol Life Sci
, vol.59
, pp. 882-893
-
-
de la Monte, S.M.1
Wands, J.R.2
-
74
-
-
79960555700
-
Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis
-
Bosco, D., Fava, A., Plastino, M., Montalcini, T., and Pujia, A., Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis. J Cell Mol Med 2011; 15(9): 1807-21.
-
(2011)
J Cell Mol Med
, vol.15
, Issue.9
, pp. 1807-1821
-
-
Bosco, D.1
Fava, A.2
Plastino, M.3
Montalcini, T.4
Pujia, A.5
-
75
-
-
0346731030
-
Neuronal thread protein regulation and interaction with microtubule-associated proteins in SHSy5y neuronal cells
-
de la Monte, S.M., Chen, G.J., Rivera, E., andWands, J.R., Neuronal thread protein regulation and interaction with microtubule-associated proteins in SHSy5y neuronal cells. Cell Mol Life Sci 2003; 60(12): 2679-91.
-
(2003)
Cell Mol Life Sci.
, vol.60
, Issue.12
, pp. 2679-2691
-
-
de la Monte, S.M.1
Chen, G.J.2
Rivera, E.3
Wands, J.R.4
-
76
-
-
0037383322
-
GSK-3: tricks of the trade for a multi-tasking kinase
-
Doble, B.W. and Woodgett, J.R., GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci 2003; 116(Pt 7): 1175-86.
-
(2003)
J Cell Sci.
, vol.116
, Issue.7
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
77
-
-
79952900458
-
Mechanisms of AD neurodegeneration may be independent of Abeta and its derivatives
-
Robakis, N.K., Mechanisms of AD neurodegeneration may be independent of Abeta and its derivatives. Neurobiol Aging 2011; 32(3): 372-9.
-
(2011)
Neurobiol Aging
, vol.32
, Issue.3
, pp. 372-379
-
-
Robakis, N.K.1
-
78
-
-
84863300949
-
Early-onset familial Alzheimer's disease (EOFAD)
-
Wu, L., Rosa-Neto, P., Hsiung, G.Y., Sadovnick, A.D., Masellis, M., Black, S.E., Jia, J., and Gauthier, S., Early-onset familial Alzheimer's disease (EOFAD). Can J Neurol Sci 2012; 39(4): 436-45.
-
(2012)
Can J Neurol Sci
, vol.39
, Issue.4
, pp. 436-445
-
-
Wu, L.1
Rosa-Neto, P.2
Hsiung, G.Y.3
Sadovnick, A.D.4
Masellis, M.5
Black, S.E.6
Jia, J.7
Gauthier, S.8
-
79
-
-
0038038865
-
Insulin increases CSF Abeta42 levels in normal older adults
-
Watson, G.S., Peskind, E.R., Asthana, S., Purganan, K.,Wait, C., Chapman, D., Schwartz, M.W., Plymate, S., and Craft, S., Insulin increases CSF Abeta42 levels in normal older adults. Neurology 2003; 60(12): 1899-903.
-
(2003)
Neurology
, vol.60
, Issue.12
, pp. 1899-1903
-
-
Watson, G.S.1
Peskind, E.R.2
Asthana, S.3
Purganan K.Wait, C.4
Chapman, D.5
Schwartz, M.W.6
Plymate, S.7
Craft, S.8
-
80
-
-
0036591657
-
Does insulin dysfunction play a role in Alzheimer's disease?
-
Gasparini, L., Netzer,W.J., Greengard, P., and Xu, H., Does insulin dysfunction play a role in Alzheimer's disease? Trends Pharmacol Sci 2002; 23(6): 288-93.
-
(2002)
Trends Pharmacol Sci.
, vol.23
, Issue.6
, pp. 288-293
-
-
Gasparini, L.1
Netzer, W.J.2
Greengard, P.3
Xu, H.4
-
81
-
-
84896709996
-
Mechanisms of brain aging regulation by insulin: implications for neurodegeneration in late-onset Alzheimer's disease
-
Schuh, A.F., Rieder, C.M., Rizzi, L., Chaves, M., and Roriz-Cruz, M., Mechanisms of brain aging regulation by insulin: implications for neurodegeneration in late-onset Alzheimer's disease. ISRN Neurol 2011; 2011: 306905.
-
(2011)
ISRN Neurol
, vol.2011
, pp. 306905
-
-
Schuh, A.F.1
Rieder, C.M.2
Rizzi, L.3
Chaves, M.4
Roriz-Cruz, M.5
-
82
-
-
30444447214
-
The role of insulin, insulin growth factor, and insulin-degrading enzyme in brain aging and Alzheimer's disease
-
Messier, C. and Teutenberg, K., The role of insulin, insulin growth factor, and insulin-degrading enzyme in brain aging and Alzheimer's disease. Neural Plast 2005; 12(4): 311-28.
-
(2005)
Neural Plast
, vol.12
, Issue.4
, pp. 311-328
-
-
Messier, C.1
Teutenberg, K.2
-
83
-
-
18744438248
-
Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor
-
Xie, L., Helmerhorst, E., Taddei, K., Plewright, B., Van Bronswijk, W., and Martins, R., Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor. J Neurosci 2002; 22(10): RC221.
-
(2002)
J Neurosci.
, vol.22
, Issue.10
, pp. RC221
-
-
Xie, L.1
Helmerhorst, E.2
Taddei, K.3
Plewright, B.4
Van Bronswijk, W.5
Martins, R.6
-
84
-
-
0034518163
-
Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway
-
Zheng, W.H., Kar, S., Dore, S., and Quirion, R., Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway. J Neural Transm Suppl 2000(60): 261-72.
-
(2000)
J Neural Transm Suppl
, vol.60
, pp. 261-272
-
-
Zheng, W.H.1
Kar, S.2
Dore, S.3
Quirion, R.4
-
85
-
-
0042839610
-
Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells
-
Tsukamoto, E., Hashimoto, Y., Kanekura, K., Niikura, T., Aiso, S., and Nishimoto, I., Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells. J Neurosci Res 2003; 73(5): 627-36.
-
(2003)
J Neurosci Res
, vol.73
, Issue.5
, pp. 627-636
-
-
Tsukamoto, E.1
Hashimoto, Y.2
Kanekura, K.3
Niikura, T.4
Aiso, S.5
Nishimoto, I.6
-
86
-
-
0032902974
-
Oxidative alterations in Alzheimer's disease
-
Markesbery, W.R. and Carney, J.M., Oxidative alterations in Alzheimer's disease. Brain Pathol 1999; 9(1): 133-46.
-
(1999)
Brain Pathol
, vol.9
, Issue.1
, pp. 133-146
-
-
Markesbery, W.R.1
Carney, J.M.2
-
87
-
-
67649678412
-
Oxidative stress in diabetes and Alzheimer's disease
-
Reddy, V.P., Zhu, X., Perry, G., and Smith, M.A., Oxidative stress in diabetes and Alzheimer's disease. Journal of Alzheimer's disease: JAD 2009; 16(4): 763-74.
-
(2009)
Journal of Alzheimer's disease: JAD
, vol.16
, Issue.4
, pp. 763-774
-
-
Reddy, V.P.1
Zhu, X.2
Perry, G.3
Smith, M.A.4
-
88
-
-
79952113682
-
Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation
-
Greilberger, J., Fuchs, D., Leblhuber, F., Greilberger, M., Wintersteiger, R., and Tafeit, E., Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation. Clinical laboratory 2010; 56(9-10): 441-8.
-
(2010)
Clinical laboratory
, vol.56
, Issue.9-10
, pp. 441-448
-
-
Greilberger, J.1
Fuchs, D.2
Leblhuber, F.3
Greilberger, M.4
Wintersteiger, R.5
Tafeit, E.6
-
89
-
-
45249120152
-
Enhanced oxidative stress is an early event during development of Alzheimer-like pathologies in presenilin conditional knock-out mice
-
Gu, F., Zhu, M., Shi, J., Hu, Y., and Zhao, Z., Enhanced oxidative stress is an early event during development of Alzheimer-like pathologies in presenilin conditional knock-out mice. Neuroscience letters 2008; 440(1): 44-8.
-
(2008)
Neuroscience letters
, vol.440
, Issue.1
, pp. 44-48
-
-
Gu, F.1
Zhu, M.2
Shi, J.3
Hu, Y.4
Zhao, Z.5
-
90
-
-
67049134478
-
Oxidative stress in Alzheimer disease
-
Gella, A. and Durany, N., Oxidative stress in Alzheimer disease. Cell adhesion & migration 2009; 3(1): 88-93.
-
(2009)
Cell adhesion & migration
, vol.3
, Issue.1
, pp. 88-93
-
-
Gella, A.1
Durany, N.2
-
91
-
-
79952785518
-
Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease
-
Rahmadi, A., Steiner, N., and Munch, G., Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease. Clinical chemistry and laboratory medicine: CCLM / FESCC 2011; 49(3): 385-91.
-
(2011)
Clinical chemistry and laboratory medicine: CCLM / FESCC
, vol.49
, Issue.3
, pp. 385-391
-
-
Rahmadi, A.1
Steiner, N.2
Munch, G.3
-
92
-
-
77956989586
-
Advanced glycation end products as biomarkers and gerontotoxins- A basis to explore methylglyoxal-lowering agents for Alzheimer's disease?
-
Krautwald, M. and Munch, G., Advanced glycation end products as biomarkers and gerontotoxins- A basis to explore methylglyoxal-lowering agents for Alzheimer's disease? Experimental gerontology 2010; 45(10): 744-51.
-
(2010)
Experimental gerontology
, vol.45
, Issue.10
, pp. 744-751
-
-
Krautwald, M.1
Munch, G.2
-
93
-
-
35948950834
-
Endoplasmic reticulum stress and liver injury
-
Kaplowitz, N., Than, T.A., Shinohara, M., and Ji, C., Endoplasmic reticulum stress and liver injury. Semin Liver Dis 2007; 27(4): 367-77.
-
(2007)
Semin Liver Dis
, vol.27
, Issue.4
, pp. 367-377
-
-
Kaplowitz, N.1
Than, T.A.2
Shinohara, M.3
Ji, C.4
-
94
-
-
56649094325
-
Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease
-
Malhi, H. and Gores, G.J., Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease. Semin Liver Dis 2008; 28(4): 360-9.
-
(2008)
Semin Liver Dis
, vol.28
, Issue.4
, pp. 360-369
-
-
Malhi, H.1
Gores, G.J.2
-
95
-
-
34249302400
-
Endoplasmic reticulum (ER) stress & diabetes
-
Sundar-Rajan, S., Srinivasan, V., Balasubramanyam, M., and Tatu, U., Endoplasmic reticulum (ER) stress & diabetes. Indian J Med Res 2007; 125(3): 411-24.
-
(2007)
Indian J Med Res
, vol.125
, Issue.3
, pp. 411-424
-
-
Sundar-Rajan, S.1
Srinivasan, V.2
Balasubramanyam, M.3
Tatu, U.4
-
96
-
-
68949161708
-
Mechanisms of nitrosamine-mediated neurodegeneration: potential relevance to sporadic Alzheimer's disease
-
de la Monte, S.M. and Tong, M., Mechanisms of nitrosamine-mediated neurodegeneration: potential relevance to sporadic Alzheimer's disease. J Alzheimer's Dis 2009; 17(4): 817-25.
-
(2009)
J Alzheimer's Dis
, vol.17
, Issue.4
, pp. 817-825
-
-
de la Monte, S.M.1
Tong, M.2
-
97
-
-
33747615232
-
Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum
-
Kaplowitz, N. and Ji, C., Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum. J Gastroenterol Hepatol 2006; 21 Suppl 3: S7-9.
-
(2006)
J Gastroenterol Hepatol
, vol.21
, Issue.3
, pp. 7-9
-
-
Kaplowitz, N.1
Ji, C.2
-
98
-
-
0347654897
-
Causes and consequences of disturbances of cerebral glucose metabolism in sporadic Alzheimer disease: therapeutic implications
-
Hoyer, S., Causes and consequences of disturbances of cerebral glucose metabolism in sporadic Alzheimer disease: therapeutic implications. Adv Exp Med Biol 2004; 541: 135-52.
-
(2004)
Adv Exp Med Biol
, vol.541
, pp. 135-152
-
-
Hoyer, S.1
-
99
-
-
34247324303
-
Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein
-
Grunblatt, E., Salkovic-Petrisic, M., Osmanovic, J., Riederer, P., and Hoyer, S., Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein. J Neurochem 2007; 101(3): 757-70.
-
(2007)
J Neurochem
, vol.101
, Issue.3
, pp. 757-770
-
-
Grunblatt, E.1
Salkovic-Petrisic, M.2
Osmanovic, J.3
Riederer, P.4
Hoyer, S.5
-
100
-
-
0142042435
-
Transient hypoxia causes Alzheimer-type molecular and biochemical abnormalities in cortical neurons: potential strategies for neuroprotection
-
Chen, G.J., Xu, J., Lahousse, S.A., Caggiano, N.L., and de la Monte, S.M., Transient hypoxia causes Alzheimer-type molecular and biochemical abnormalities in cortical neurons: potential strategies for neuroprotection. J Alzheimer's Dis 2003; 5(3): 209-28.
-
(2003)
J Alzheimer's Dis
, vol.5
, Issue.3
, pp. 209-228
-
-
Chen, G.J.1
Xu, J.2
Lahousse, S.A.3
Caggiano, N.L.4
de la Monte, S.M.5
-
101
-
-
33748755428
-
Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease
-
de la Monte, S.M., Tong, M., Lester-Coll, N., Plater, M., Jr., and Wands, J.R., Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease. J Alzheimer's Dis 2006; 10(1): 89-109.
-
(2006)
J Alzheimer's Dis
, vol.10
, Issue.1
, pp. 89-109
-
-
de la Monte, S.M.1
Tong, M.2
Lester-Coll, N.3
Plater, M.Jr.4
Wands, J.R.5
-
103
-
-
0032229658
-
Cerebrovascular pathology contributes to the heterogeneity of Alzheimer's disease
-
Etiene, D., Kraft, J., Ganju, N., Gomez-Isla, T., Gemelli, B., Hyman, B.T., Hedley-Whyte, E.T., Wands, J.R., and De La Monte, S.M., Cerebrovascular pathology contributes to the heterogeneity of Alzheimer's disease. J Alzheimer's Dis 1998; 1(2): 119-34.
-
(1998)
J Alzheimer's Dis
, vol.1
, Issue.2
, pp. 119-134
-
-
Etiene, D.1
Kraft, J.2
Ganju, N.3
Gomez-Isla, T.4
Gemelli, B.5
Hyman, B.T.6
Hedley-Whyte, E.T.7
Wands, J.R.8
De La Monte, S.M.9
-
104
-
-
33845462866
-
Brain aging in very old men with type 2 diabetes: the Honolulu-Asia Aging Study
-
Korf, E.S., White, L.R., Scheltens, P., and Launer, L.J., Brain aging in very old men with type 2 diabetes: the Honolulu-Asia Aging Study. Diabetes care 2006; 29(10): 2268-74.
-
(2006)
Diabetes care
, vol.29
, Issue.10
, pp. 2268-2274
-
-
Korf, E.S.1
White, L.R.2
Scheltens, P.3
Launer, L.J.4
-
105
-
-
2642513115
-
Hypothesis: obesity and the insulin resistance syndrome play a major role in end-stage renal failure attributed to hypertension and labelled 'hypertensive nephrosclerosis'
-
Kincaid-Smith, P., Hypothesis: obesity and the insulin resistance syndrome play a major role in end-stage renal failure attributed to hypertension and labelled 'hypertensive nephrosclerosis'. J Hypertens 2004; 22(6): 1051-5.
-
(2004)
J Hypertens
, vol.22
, Issue.6
, pp. 1051-1055
-
-
Kincaid-Smith, P.1
-
106
-
-
21644472959
-
Insulin resistance contributes to obesity-related proteinuria
-
Matsumoto, H., Nakao, T., Okada, T., Nagaoka, Y., Iwasawa, H., Tomaru, R., and Wada, T., Insulin resistance contributes to obesity-related proteinuria. Intern Med 2005; 44(6): 548-53.
-
(2005)
Intern Med
, vol.44
, Issue.6
, pp. 548-553
-
-
Matsumoto, H.1
Nakao, T.2
Okada, T.3
Nagaoka, Y.4
Iwasawa, H.5
Tomaru, R.6
Wada, T.7
-
107
-
-
43549110513
-
Role of imaging techniques in the diagnosis of dementia
-
O'Brien, J.T., Role of imaging techniques in the diagnosis of dementia. Br J Radiol 2007; 80 Spec No 2: S71-7.
-
(2007)
Br J Radiol
, vol.80
, Issue.2
, pp. 71-77
-
-
O'Brien, J.T.1
-
108
-
-
80052373489
-
A visual [18F]FDG-PET rating scale for the differential diagnosis of frontotemporal lobar degeneration
-
Poljansky, S., Ibach, B., Hirschberger, B., Manner, P., Klunemann, H., Hajak, G., and Marienhagen, J., A visual [18F]FDG-PET rating scale for the differential diagnosis of frontotemporal lobar degeneration. Eur Arch Psychiatry Clin Neurosci 2011; 261(6): 433-46.
-
(2011)
Eur Arch Psychiatry Clin Neurosci.
, vol.261
, Issue.6
, pp. 433-446
-
-
Poljansky, S.1
Ibach, B.2
Hirschberger, B.3
Manner, P.4
Klunemann, H.5
Hajak, G.6
Marienhagen, J.7
-
109
-
-
77958554594
-
Typical cerebral metabolic patterns in neurodegenerative brain diseases
-
Teune, L.K., Bartels, A.L., de Jong, B.M.,Willemsen, A.T., Eshuis, S.A., de Vries, J.J., van Oostrom, J.C., and Leenders, K.L., Typical cerebral metabolic patterns in neurodegenerative brain diseases. Mov Disord 2010; 25(14): 2395-404.
-
(2010)
Mov Disord
, vol.25
, Issue.14
, pp. 2395-2404
-
-
Teune, L.K.1
Bartels, A.L.2
de Jong, B.M.3
Willemsen, A.T.4
Eshuis, S.A.5
de Vries, J.J.6
van Oostrom, J.C.7
Leenders, K.L.8
-
110
-
-
79957947433
-
Removing protein aggregates: the role of proteolysis in neurodegeneration
-
Nijholt, D.A., De Kimpe, L., Elfrink, H.L., Hoozemans, J.J., and Scheper,W., Removing protein aggregates: the role of proteolysis in neurodegeneration. Curr Med Chem 2011; 18(16): 2459-76.
-
(2011)
Curr Med Chem
, vol.18
, Issue.16
, pp. 2459-2476
-
-
Nijholt, D.A.1
De Kimpe, L.2
Elfrink, H.L.3
Hoozemans, J.J.4
Scheper, W.5
-
111
-
-
34247098374
-
Accumulation of misfolded protein through nitrosative stress linked to neurodegenerative disorders
-
Uehara, T., Accumulation of misfolded protein through nitrosative stress linked to neurodegenerative disorders. Antioxid Redox Signal 2007; 9(5): 597-601.
-
(2007)
Antioxid Redox Signal
, vol.9
, Issue.5
, pp. 597-601
-
-
Uehara, T.1
-
112
-
-
33750057386
-
Ubiquitin proteasome system as a pharmacological target in neurodegeneration
-
Hol, E.M., Fischer, D.F., Ovaa, H., and Scheper, W., Ubiquitin proteasome system as a pharmacological target in neurodegeneration. Expert Rev Neurother 2006; 6(9): 1337-47.
-
(2006)
Expert Rev Neurother
, vol.6
, Issue.9
, pp. 1337-1347
-
-
Hol, E.M.1
Fischer, D.F.2
Ovaa, H.3
Scheper, W.4
-
113
-
-
4444370179
-
How does parkin ligate ubiquitin to Parkinson's disease?
-
Kahle, P.J. and Haass, C., How does parkin ligate ubiquitin to Parkinson's disease? EMBO Rep 2004; 5(7): 681-5.
-
(2004)
EMBO Rep
, vol.5
, Issue.7
, pp. 681-685
-
-
Kahle, P.J.1
Haass, C.2
-
114
-
-
33646176558
-
ER stress and UPR in familial amyotrophic lateral sclerosis
-
Turner, B.J. and Atkin, J.D., ER stress and UPR in familial amyotrophic lateral sclerosis. Curr Mol Med 2006; 6(1): 79-86.
-
(2006)
Curr Mol Med
, vol.6
, Issue.1
, pp. 79-86
-
-
Turner, B.J.1
Atkin, J.D.2
-
115
-
-
82455175237
-
Effects of unilateral nigrostriatal dopamine depletion on peripheral glucose tolerance and insulin signaling in middle aged rats
-
Morris, J.K., Seim, N.B., Bomhoff, G.L., Geiger, P.C., and Stanford, J.A., Effects of unilateral nigrostriatal dopamine depletion on peripheral glucose tolerance and insulin signaling in middle aged rats. Neurosci Lett 2011; 504(3): 219-22.
-
(2011)
Neurosci Lett
, vol.504
, Issue.3
, pp. 219-222
-
-
Morris, J.K.1
Seim, N.B.2
Bomhoff, G.L.3
Geiger, P.C.4
Stanford, J.A.5
-
116
-
-
65549103889
-
Brain insulin-like growth factor and neurotrophin resistance in Parkinson's disease and dementia with Lewy bodies: potential role of manganese neurotoxicity
-
Tong, M., Dong, M., and de la Monte, S.M., Brain insulin-like growth factor and neurotrophin resistance in Parkinson's disease and dementia with Lewy bodies: potential role of manganese neurotoxicity. J Alzheimer's Dis 2009; 16(3): 585-99.
-
(2009)
J Alzheimer's Dis
, vol.16
, Issue.3
, pp. 585-599
-
-
Tong, M.1
Dong, M.2
de la Monte, S.M.3
-
117
-
-
79951754336
-
Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus: a missing link to therapeutic potential
-
Sato, N., Takeda, S., Uchio-Yamada, K., Ueda, H., Fujisawa, T., Rakugi, H., and Morishita, R., Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus: a missing link to therapeutic potential. Curr Aging Sci 2011; 4(2): 118-27.
-
(2011)
Curr Aging Sci.
, vol.4
, Issue.2
, pp. 118-127
-
-
Sato, N.1
Takeda, S.2
Uchio-Yamada, K.3
Ueda, H.4
Fujisawa, T.5
Rakugi, H.6
Morishita, R.7
-
118
-
-
82755179516
-
Igf-I signaling and effects on longevity
-
discussion 246-9
-
Holzenberger, M., Igf-I signaling and effects on longevity. Nestle Nutr Workshop Ser Pediatr Program 2011; 68: 237-45; discussion 246-9.
-
(2011)
Nestle Nutr Workshop Ser Pediatr Program
, vol.68
, pp. 237-45
-
-
Holzenberger, M.1
-
119
-
-
84861234650
-
Manipulation of in vivo iron levels can alter resistance to oxidative stress without affecting ageing in the nematode C elegans
-
Valentini, S., Cabreiro, F., Ackerman, D., Alam, M.M., Kunze, M.B., Kay, C.W., and Gems, D., Manipulation of in vivo iron levels can alter resistance to oxidative stress without affecting ageing in the nematode C. elegans. Mech Ageing Dev 2012; 133(5): 282-90.
-
(2012)
Mech Ageing Dev
, vol.133
, Issue.5
, pp. 282-290
-
-
Valentini, S.1
Cabreiro, F.2
Ackerman, D.3
Alam, M.M.4
Kunze, M.B.5
Kay, C.W.6
Gems, D.7
-
120
-
-
84896733263
-
Neuronal overexpression of insulin receptor substrate 2 leads to increased fat mass, insulin resistance, and glucose intolerance during aging
-
Zemva, J., Udelhoven, M., Moll, L., Freude, S., Stohr, O., Bronneke, H.S., Drake, R.B., Krone, W., and Schubert, M., Neuronal overexpression of insulin receptor substrate 2 leads to increased fat mass, insulin resistance, and glucose intolerance during aging. Age (Dordr) 2012.
-
(2012)
Age (Dordr)
-
-
Zemva, J.1
Udelhoven, M.2
Moll, L.3
Freude, S.4
Stohr, O.5
Bronneke, H.S.6
Drake, R.B.7
Krone, W.8
Schubert, M.9
-
121
-
-
79959881826
-
Hepatoprotection and neuroprotection induced by low doses of IGF-II in aging rats
-
Castilla-Cortazar, I., Garcia-Fernandez, M., Delgado, G., Puche, J.E., Sierra, I., Barhoum, R., and Gonzalez-Baron, S., Hepatoprotection and neuroprotection induced by low doses of IGF-II in aging rats. J Transl Med 2011; 9: 103.
-
(2011)
J Transl Med
, vol.9
, pp. 103
-
-
Castilla-Cortazar, I.1
Garcia-Fernandez, M.2
Delgado, G.3
Puche, J.E.4
Sierra, I.5
Barhoum, R.6
Gonzalez-Baron, S.7
-
122
-
-
79251638798
-
Metabolic impact of adult-onset, isolated, growth hormone deficiency (AOiGHD) due to destruction of pituitary somatotropes
-
Luque, R.M., Lin, Q., Cordoba-Chacon, J., Subbaiah, P.V., Buch, T., Waisman, A., Vankelecom, H., and Kineman, R.D., Metabolic impact of adult-onset, isolated, growth hormone deficiency (AOiGHD) due to destruction of pituitary somatotropes. PLoS One 2011; 6(1): e15767.
-
(2011)
PLoS One
, vol.6
, Issue.1
, pp. 15767
-
-
Luque, R.M.1
Lin, Q.2
Cordoba-Chacon, J.3
Subbaiah, P.V.4
Buch, T.5
Waisman, A.6
Vankelecom, H.7
Kineman, R.D.8
-
123
-
-
84879700411
-
Methylglyoxal, cognitive function and cerebral atrophy in older people
-
Srikanth, V., Westcott, B., Forbes, J., Phan, T.G., Beare, R., Venn, A., Pearson, S., Greenaway, T., Parameswaran, V., and Munch, G., Methylglyoxal, cognitive function and cerebral atrophy in older people. J Gerontol A Biol Sci Med Sci 2012.
-
(2012)
J Gerontol A Biol Sci Med.
-
-
Srikanth, V.1
Westcott, B.2
Forbes, J.3
Phan, T.G.4
Beare, R.5
Venn, A.6
Pearson, S.7
Greenaway, T.8
Parameswaran, V.9
Munch, G.10
-
124
-
-
84864921644
-
Insulin resistance in the brain: an old-age or newage problem?
-
Williamson, R., McNeilly, A., and Sutherland, C., Insulin resistance in the brain: an old-age or newage problem? Biochem Pharmacol 2012; 84(6): 737-45.
-
(2012)
Biochem Pharmacol
, vol.84
, Issue.6
, pp. 737-745
-
-
Williamson, R.1
McNeilly, A.2
Sutherland, C.3
-
125
-
-
84874021086
-
Interferon-gamma -inducible inflammation: contribution to aging and aging-associated psychiatric disorders
-
Oxenkrug, G., Interferon-gamma -inducible inflammation: contribution to aging and aging-associated psychiatric disorders. Aging Dis 2011; 2(6): 474-86.
-
(2011)
Aging Dis
, vol.2
, Issue.6
, pp. 474-486
-
-
Oxenkrug, G.1
-
126
-
-
79959248656
-
Age-associated development of inflammation inWistar rats: effects of caloric restriction
-
Horrillo, D., Sierra, J., Arribas, C., Garcia-San Frutos, M., Carrascosa, J.M., Lauzurica, N., Fernandez-Agullo, T., and Ros, M., Age-associated development of inflammation inWistar rats: effects of caloric restriction. Arch Physiol Biochem 2011; 117(3): 140-50.
-
(2011)
Arch Physiol Biochem
, vol.117
, Issue.3
, pp. 140-150
-
-
Horrillo, D.1
Sierra, J.2
Arribas, C.3
Garcia-San Frutos, M.4
Carrascosa, J.M.5
Lauzurica, N.6
Fernandez-Agullo, T.7
Ros, M.8
-
127
-
-
84863431784
-
Inflammatory cause of metabolic syndrome via brain stress and NF-kappaB
-
Cai, D. and Liu, T., Inflammatory cause of metabolic syndrome via brain stress and NF-kappaB. Aging (Albany NY) 2012; 4(2): 98-115.
-
(2012)
Aging (Albany NY)
, vol.4
, Issue.2
, pp. 98-115
-
-
Cai, D.1
Liu, T.2
-
128
-
-
0027461963
-
Poliomyelitis and the post-polio syndrome: exercise capacities and adaptation-current research, future directions, and widespread applicability
-
Birk, T.J., Poliomyelitis and the post-polio syndrome: exercise capacities and adaptation-current research, future directions, and widespread applicability. Med Sci Sports Exerc 1993; 25(4): 466-72.
-
(1993)
Med Sci. Sports Exerc
, vol.25
, Issue.4
, pp. 466-472
-
-
Birk, T.J.1
-
129
-
-
0023498414
-
Neurological manifestations of the post-polio syndrome
-
Jubelt, B. and Cashman, N.R., Neurological manifestations of the post-polio syndrome. Crit Rev Neurobiol 1987; 3(3): 199-220.
-
(1987)
Crit Rev Neurobiol
, vol.3
, Issue.3
, pp. 199-220
-
-
Jubelt, B.1
Cashman, N.R.2
-
130
-
-
1842607229
-
Adaptive and maladaptive motor axonal sprouting in aging and motoneuron disease
-
Gordon, T., Hegedus, J., and Tam, S.L., Adaptive and maladaptive motor axonal sprouting in aging and motoneuron disease. Neurol Res 2004; 26(2): 174-85.
-
(2004)
Neurol Res
, vol.26
, Issue.2
, pp. 174-185
-
-
Gordon, T.1
Hegedus, J.2
Tam, S.L.3
-
131
-
-
0029050269
-
Pathogenetic mechanisms of postpolio syndrome: morphological, electrophysiological, virological, and immunological correlations
-
Dalakas, M.C., Pathogenetic mechanisms of postpolio syndrome: morphological, electrophysiological, virological, and immunological correlations. Ann N Y Acad Sci 1995; 753: 167-85.
-
(1995)
Ann N Y Acad Sci.
, vol.753
, pp. 167-185
-
-
Dalakas, M.C.1
-
132
-
-
79955551252
-
Obesity, diabetes mellitus, and liver fibrosis
-
Chiang, D.J., Pritchard, M.T., and Nagy, L.E., Obesity, diabetes mellitus, and liver fibrosis. American journal of physiology. Gastrointestinal and liver physiology 2011; 300(5): G697-702.
-
(2011)
American journal of physiology. Gastrointestinal and liver physiology
, vol.300
, Issue.5
, pp. 697-702
-
-
Chiang, D.J.1
Pritchard, M.T.2
Nagy, L.E.3
-
133
-
-
79960029926
-
Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
-
Vernon, G., Baranova, A., and Younossi, Z.M., Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment Pharmacol Ther 2011; 34(3): 274-85.
-
(2011)
Aliment Pharmacol Ther
, vol.34
, Issue.3
, pp. 274-285
-
-
Vernon, G.1
Baranova, A.2
Younossi, Z.M.3
-
134
-
-
67649687040
-
Hepatic ceramide may mediate brain insulin resistance and neurodegeneration in type 2 diabetes and non-alcoholic steatohepatitis
-
Lyn-Cook, L.E., Jr., Lawton, M., Tong, M., Silbermann, E., Longato, L., Jiao, P., Mark, P.,Wands, J.R., Xu, H., and de la Monte, S.M., Hepatic ceramide may mediate brain insulin resistance and neurodegeneration in type 2 diabetes and non-alcoholic steatohepatitis. J Alzheimer's Dis 2009; 16(4): 715-29.
-
(2009)
J Alzheimer's Dis
, vol.16
, Issue.4
, pp. 715-729
-
-
Lyn-Cook, L.E.1
Lawton, M.2
Tong, M.3
Silbermann, E.4
Longato, L.5
Jiao, P.6
Mark P.Wands, J.R.7
Xu, H.8
de la Monte, S.M.9
-
135
-
-
68949089312
-
Alzheimer's disease is type 3 diabetes: evidence reviewed
-
de la Monte, S.M. and Wands, J.R., Alzheimer's disease is type 3 diabetes: evidence reviewed. J Diabetes Sci Tech 2008; 2(6): 1101-113.
-
(2008)
J Diabetes Sci. Tech
, vol.2
, Issue.6
, pp. 1101-1113
-
-
de la Monte, S.M.1
Wands, J.R.2
-
136
-
-
43249083481
-
Free fatty acids and skeletal muscle insulin resistance
-
Kraegen, E.W. and Cooney, G.J., Free fatty acids and skeletal muscle insulin resistance. Curr Opin Lipidol 2008; 19(3): 235-41.
-
(2008)
Curr Opin Lipidol
, vol.19
, Issue.3
, pp. 235-241
-
-
Kraegen, E.W.1
Cooney, G.J.2
-
137
-
-
34247110809
-
Relation of diabetes to mild cognitive impairment
-
Luchsinger, J.A., Reitz, C., Patel, B., Tang, M.X., Manly, J.J., and Mayeux, R., Relation of diabetes to mild cognitive impairment. Arch Neurol 2007; 64(4): 570-5.
-
(2007)
Arch Neurol
, vol.64
, Issue.4
, pp. 570-575
-
-
Luchsinger, J.A.1
Reitz, C.2
Patel, B.3
Tang, M.X.4
Manly, J.J.5
Mayeux, R.6
-
138
-
-
34147173277
-
Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment
-
Craft, S., Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment. Curr Alzheimer Res 2007; 4(2): 147-52.
-
(2007)
Curr Alzheimer Res
, vol.4
, Issue.2
, pp. 147-152
-
-
Craft, S.1
-
139
-
-
70249093603
-
Boeka, A.G., Austin, H.M., Gunstad, J., and Harmon, C.M., Evidence of executive dysfunction in extremely obese adolescents: a pilot study
-
Lokken, K.L., Boeka, A.G., Austin, H.M., Gunstad, J., and Harmon, C.M., Evidence of executive dysfunction in extremely obese adolescents: a pilot study. Surgery for obesity and related diseases: official journal of the American Society for Bariatric Surgery 2009; 5(5): 547-52.
-
(2009)
Surgery for obesity and related diseases: official journal of the American Society for Bariatric Surgery
, vol.5
, Issue.5
, pp. 547-552
-
-
Lokken, K.L.1
-
140
-
-
37849185832
-
Elevated body mass index is associated with executive dysfunction in otherwise healthy adults
-
Gunstad, J., Paul, R.H., Cohen, R.A., Tate, D.F., Spitznagel, M.B., and Gordon, E., Elevated body mass index is associated with executive dysfunction in otherwise healthy adults. Comprehensive psychiatry 2007; 48(1): 57-61.
-
(2007)
Comprehensive psychiatry
, vol.48
, Issue.1
, pp. 57-61
-
-
Gunstad, J.1
Paul, R.H.2
Cohen, R.A.3
Tate, D.F.4
Spitznagel, M.B.5
Gordon, E.6
-
141
-
-
34147119059
-
Metabolic syndrome and cognitive decline
-
Yaffe, K., Metabolic syndrome and cognitive decline. Curr Alzheimer Res 2007; 4(2): 123-6.
-
(2007)
Curr Alzheimer Res
, vol.4
, Issue.2
, pp. 123-126
-
-
Yaffe, K.1
-
142
-
-
28444459843
-
Studies of the effects of high fat diets on cognitive function in a rat model
-
Winocur, G. and Greenwood, C.E., Studies of the effects of high fat diets on cognitive function in a rat model. Neurobiol Aging 2005; 26 Suppl 1: 46-9.
-
(2005)
Neurobiol Aging
, vol.26
, Issue.1
, pp. 46-49
-
-
Winocur, G.1
Greenwood, C.E.2
-
143
-
-
52449087540
-
Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus
-
Moroz, N., Tong, M., Longato, L., Xu, H., and de la Monte, S.M., Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus. J Alzheimer's Dis 2008; 15(1): 29-44.
-
(2008)
J Alzheimer's Dis
, vol.15
, Issue.1
, pp. 29-44
-
-
Moroz, N.1
Tong, M.2
Longato, L.3
Xu, H.4
de la Monte, S.M.5
-
144
-
-
78650827898
-
Aerobic exercise improves cognition for older adults with glucose intolerance, a risk factor for Alzheimer's disease
-
Baker, L.D., Frank, L.L., Foster-Schubert, K., Green, P.S., Wilkinson, C.W., McTiernan, A., Cholerton, B.A., Plymate, S.R., Fishel, M.A., Watson, G.S., Duncan, G.E., Mehta, P.D., and Craft, S., Aerobic exercise improves cognition for older adults with glucose intolerance, a risk factor for Alzheimer's disease. J Alzheimer's Dis 2010; 22(2): 569-79.
-
(2010)
J Alzheimer's Dis
, vol.22
, Issue.2
, pp. 569-579
-
-
Baker, L.D.1
Frank, L.L.2
Foster-Schubert, K.3
Green, P.S.4
Wilkinson, C.W.5
McTiernan, A.6
Cholerton, B.A.7
Plymate, S.R.8
Fishel, M.A.9
Watson, G.S.10
Duncan, G.E.11
Mehta, P.D.12
Craft, S.13
-
145
-
-
74949118967
-
Effects of aerobic exercise on mild cognitive impairment: a controlled trial
-
Baker, L.D., Frank, L.L., Foster-Schubert, K., Green, P.S.,Wilkinson, C.W., McTiernan, A., Plymate, S.R., Fishel, M.A.,Watson, G.S., Cholerton, B.A., Duncan, G.E., Mehta, P.D., and Craft, S., Effects of aerobic exercise on mild cognitive impairment: a controlled trial. Arch Neurol 2010; 67(1): 71-9.
-
(2010)
Arch Neurol
, vol.67
, Issue.1
, pp. 71-79
-
-
Baker, L.D.1
Frank, L.L.2
Foster-Schubert, K.3
Green P.S.Wilkinson, C.W.4
McTiernan, A.5
Plymate, S.R.6
Fishel M.A.Watson, G.S.7
Cholerton, B.A.8
Duncan, G.E.9
Mehta, P.D.10
Craft, S.11
-
146
-
-
0034971168
-
The effect of weightloss dieting on cognitive performance and psychological well-being in overweight women
-
Bryan, J. and Tiggemann, M., The effect of weightloss dieting on cognitive performance and psychological well-being in overweight women. Appetite 2001; 36(2): 147-56.
-
(2001)
Appetite
, vol.36
, Issue.2
, pp. 147-156
-
-
Bryan, J.1
Tiggemann, M.2
-
147
-
-
78650809747
-
Mediterranean diet, inflammatory and metabolic biomarkers, and risk of Alzheimer's disease
-
Gu, Y., Luchsinger, J.A., Stern, Y., and Scarmeas, N., Mediterranean diet, inflammatory and metabolic biomarkers, and risk of Alzheimer's disease. J Alzheimer's Dis 2010; 22(2): 483-92.
-
(2010)
J Alzheimer's Dis
, vol.22
, Issue.2
, pp. 483-492
-
-
Gu, Y.1
Luchsinger, J.A.2
Stern, Y.3
Scarmeas, N.4
-
148
-
-
33751570625
-
Diabetes mellitus and dementia
-
Pasquier, F., Boulogne, A., Leys, D., and Fontaine, P., Diabetes mellitus and dementia. Diabetes Metab 2006; 32(5 Pt 1): 403-14.
-
(2006)
Diabetes Metab
, vol.32
, Issue.5 PART. 1
, pp. 403-414
-
-
Pasquier, F.1
Boulogne, A.2
Leys, D.3
Fontaine, P.4
-
149
-
-
33746565284
-
Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease
-
Martins, I.J., Hone, E., Foster, J.K., Sunram-Lea, S.I., Gnjec, A., Fuller, S.J., Nolan, D., Gandy, S.E., and Martins, R.N., Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease. Mol Psychiatry 2006; 11(8): 721-36.
-
(2006)
Mol Psychiatry
, vol.11
, Issue.8
, pp. 721-736
-
-
Martins, I.J.1
Hone, E.2
Foster, J.K.3
Sunram-Lea, S.I.4
Gnjec, A.5
Fuller, S.J.6
Nolan, D.7
Gandy, S.E.8
Martins, R.N.9
-
150
-
-
34548711907
-
Type 2 diabetes and risk of cognitive impairment and dementia
-
Whitmer, R.A., Type 2 diabetes and risk of cognitive impairment and dementia. Curr Neurol Neurosci Rep 2007; 7(5): 373-80.
-
(2007)
Curr Neurol Neurosci Rep
, vol.7
, Issue.5
, pp. 373-380
-
-
Whitmer, R.A.1
-
151
-
-
67749108405
-
Human cerebral neuropathology of type 2 diabetes mellitus
-
Nelson, P.T., Smith, C.D., Abner, E.A., Schmitt, F.A., Scheff, S.W., Davis, G.J., Keller, J.N., Jicha, G.A., Davis, D., Wang-Xia, W., Hartman, A., Katz, D.G., and Markesbery, W.R., Human cerebral neuropathology of type 2 diabetes mellitus. Biochim Biophys Acta 2008.
-
(2008)
Biochim Biophys Acta
-
-
Nelson, P.T.1
Smith, C.D.2
Abner, E.A.3
Schmitt, F.A.4
Scheff, S.W.5
Davis, G.J.6
Keller, J.N.7
Jicha, G.A.8
Davis, D.9
Wang-Xia, W.10
Hartman, A.11
Katz, D.G.12
Markesbery, W.R.13
-
152
-
-
0842309993
-
Increased risk of type 2 diabetes in Alzheimer disease
-
Janson, J., Laedtke, T., Parisi, J.E., O'Brien, P., Petersen, R.C., and Butler, P.C., Increased risk of type 2 diabetes in Alzheimer disease. Diabetes 2004; 53(2): 474-81.
-
(2004)
Diabetes
, vol.53
, Issue.2
, pp. 474-481
-
-
Janson, J.1
Laedtke, T.2
Parisi, J.E.3
O'Brien, P.4
Petersen, R.C.5
Butler, P.C.6
-
153
-
-
77953004836
-
Early limited nitrosamine exposures exacerbate high fat diet-mediated type2 diabetes and neurodegeneration
-
Tong, M., Longato, L., and de la Monte, S.M., Early limited nitrosamine exposures exacerbate high fat diet-mediated type2 diabetes and neurodegeneration. BMC Endocr Disord 2010; 10(1): 4.
-
(2010)
BMC Endocr Disord
, vol.10
, Issue.1
, pp. 4
-
-
Tong, M.1
Longato, L.2
de la Monte, S.M.3
-
154
-
-
34147132771
-
Body mass index in midlife and risk of Alzheimer disease and vascular dementia
-
Whitmer, R.A., Gunderson, E.P., Quesenberry, C.P., Jr., Zhou, J., andYaffe, K., Body mass index in midlife and risk of Alzheimer disease and vascular dementia. Curr Alzheimer Res 2007; 4(2): 103-9.
-
(2007)
Curr Alzheimer Res
, vol.4
, Issue.2
, pp. 103-109
-
-
Whitmer, R.A.1
Gunderson, E.P.2
Quesenberry, C.P.3
Zhou, J.4
Yaffe, K.5
-
155
-
-
38649108842
-
Cognitive dysfunction in chronic hepatitis C: a review
-
Perry,W., Hilsabeck, R.C., and Hassanein, T.I., Cognitive dysfunction in chronic hepatitis C: a review. Dig Dis Sci 2008; 53(2): 307-21.
-
(2008)
Dig Dis Sci.
, vol.53
, Issue.2
, pp. 307-321
-
-
Perry, W.1
Hilsabeck, R.C.2
Hassanein, T.I.3
-
156
-
-
33750492618
-
Psychiatric behavioral aspects of comanagement of hepatitis C virus and HIV
-
Weiss, J.J. and Gorman, J.M., Psychiatric behavioral aspects of comanagement of hepatitis C virus and HIV. Curr HIV/AIDS Rep 2006; 3(4): 176-81.
-
(2006)
Curr HIV/AIDS Rep
, vol.3
, Issue.4
, pp. 176-181
-
-
Weiss, J.J.1
Gorman, J.M.2
-
157
-
-
68249127000
-
Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's disease
-
Tong, M., Neusner, A., Longato, L., Lawton, M., Wands, J.R., and de la Monte, S.M., Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's disease. J Alzheimer's Dis 2009.
-
(2009)
J Alzheimer's Dis
-
-
Tong, M.1
Neusner, A.2
Longato, L.3
Lawton, M.4
Wands, J.R.5
de la Monte, S.M.6
-
158
-
-
0033064602
-
Effects of insulin on lipid metabolism of larvae and metamorphosing landlocked sea lamprey, Petromyzon marinus
-
Kao, Y., Youson, J.H., Holmes, J.A., Al-Mahrouki, A., and Sheridan, M.A., Effects of insulin on lipid metabolism of larvae and metamorphosing landlocked sea lamprey, Petromyzon marinus. Gen Comp Endocrinol 1999; 114(3): 405-14.
-
(1999)
Gen Comp Endocrinol
, vol.114
, Issue.3
, pp. 405-414
-
-
Kao, Y.1
Youson, J.H.2
Holmes, J.A.3
Al-Mahrouki, A.4
Sheridan, M.A.5
-
159
-
-
45149106053
-
Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism
-
Holland, W.L. and Summers, S.A., Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism. Endocr Rev 2008; 29(4): 381-402.
-
(2008)
Endocr Rev
, vol.29
, Issue.4
, pp. 381-402
-
-
Holland, W.L.1
Summers, S.A.2
-
160
-
-
67349130083
-
Glycosphingolipids and insulin resistance
-
Langeveld, M. and Aerts, J.M., Glycosphingolipids and insulin resistance. Prog Lipid Res 2009; 48(3-4): 196-205.
-
(2009)
Prog Lipid Res
, vol.48
, Issue.3-4
, pp. 196-205
-
-
Langeveld, M.1
Aerts, J.M.2
-
161
-
-
33748038468
-
Depression, anxiety, and nonalcoholic steatohepatitis
-
Elwing, J.E., Lustman, P.J., Wang, H.L., and Clouse, R.E., Depression, anxiety, and nonalcoholic steatohepatitis. Psychosom Med 2006; 68(4): 563-9.
-
(2006)
Psychosom Med
, vol.68
, Issue.4
, pp. 563-569
-
-
Elwing, J.E.1
Lustman, P.J.2
Wang, H.L.3
Clouse, R.E.4
-
162
-
-
85018942203
-
Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy
-
Felipo, V., Urios, A., Montesinos, E., Molina, I., Garcia-Torres, M.L., Civera, M., Del Olmo, J.A., Ortega, J., Martinez-Valls, J., Serra, M.A., Cassinello, N., Wassel, A., Jorda, E., and Montoliu, C., Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy. Metabolic brain disease 2011.
-
(2011)
Metabolic brain disease
-
-
Felipo, V.1
Urios, A.2
Montesinos, E.3
Molina, I.4
Garcia-Torres, M.L.5
Civera, M.6
Del Olmo, J.A.7
Ortega, J.8
Martinez-Valls, J.9
Serra, M.A.10
Cassinello, N.11
Wassel, A.12
Jorda, E.13
Montoliu, C.14
-
163
-
-
26644468852
-
The neuropsychological profile of alcohol-related dementia suggests cortical and subcortical pathology
-
Schmidt, K.S., Gallo, J.L., Ferri, C., Giovannetti, T., Sestito, N., Libon, D.J., and Schmidt, P.S., The neuropsychological profile of alcohol-related dementia suggests cortical and subcortical pathology. Dement Geriatr Cogn Disord 2005; 20(5): 286-91.
-
(2005)
Dement Geriatr Cogn Disord
, vol.20
, Issue.5
, pp. 286-291
-
-
Schmidt, K.S.1
Gallo, J.L.2
Ferri, C.3
Giovannetti, T.4
Sestito, N.5
Libon, D.J.6
Schmidt, P.S.7
-
164
-
-
61449257436
-
The Korsakoff syndrome: clinical aspects, psychology and treatment
-
Kopelman, M.D., Thomson, A.D., Guerrini, I., and Marshall, E.J., The Korsakoff syndrome: clinical aspects, psychology and treatment. Alcohol Alcohol 2009; 44(2): 148-54.
-
(2009)
Alcohol Alcohol
, vol.44
, Issue.2
, pp. 148-154
-
-
Kopelman, M.D.1
Thomson, A.D.2
Guerrini, I.3
Marshall, E.J.4
-
165
-
-
84862999971
-
Triangulated mal-signaling in Alzheimer's Disease: Roles of neurotoxic ceramides, ER stress, and insulin resistance reviewed
-
de la Monte, S.M., Triangulated mal-signaling in Alzheimer's Disease: Roles of neurotoxic ceramides, ER stress, and insulin resistance reviewed. J Alzheimer's Dis 2012; 30: S231-S249.
-
(2012)
J Alzheimer's Dis
, vol.30
, pp. 231-249
-
-
de la Monte, S.M.1
-
166
-
-
76249083449
-
Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment
-
de la Monte, S.M., Tong, M., Lawton, M., and Longato, L., Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment. Mol Neurodegener 2009; 4: 54.
-
(2009)
Mol Neurodegener
, vol.4
, pp. 54
-
-
de la Monte, S.M.1
Tong, M.2
Lawton, M.3
Longato, L.4
-
167
-
-
77957259099
-
Ceramidemediated insulin resistance and impairment of cognitive-motor functions
-
de la Monte, S.M., Tong, M., Nguyen, V., Setshedi, M., Longato, L., and Wands, J.R., Ceramidemediated insulin resistance and impairment of cognitive-motor functions. Journal of Alzheimer's disease: JAD 2010; 21(3): 967-84.
-
(2010)
Journal of Alzheimer's disease: JAD
, vol.21
, Issue.3
, pp. 967-984
-
-
de la Monte, S.M.1
Tong, M.2
Nguyen, V.3
Setshedi, M.4
Longato, L.5
Wands, J.R.6
-
168
-
-
67649723058
-
Mechanisms of ceramide-mediated neurodegeneration
-
Tong, M. and de la Monte, S.M., Mechanisms of ceramide-mediated neurodegeneration. J Alzheimer's Dis 2009; 16(4): 705-14.
-
(2009)
J Alzheimer's Dis
, vol.16
, Issue.4
, pp. 705-714
-
-
Tong, M.1
de la Monte, S.M.2
-
169
-
-
1442357755
-
Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development of Alzheimer's disease
-
Alessenko, A.V., Bugrova, A.E., and Dudnik, L.B., Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development of Alzheimer's disease. Biochem Soc Trans 2004; 32(Pt 1): 144-6.
-
(2004)
Biochem Soc Trans
, vol.32
, Issue.1
, pp. 144-146
-
-
Alessenko, A.V.1
Bugrova, A.E.2
Dudnik, L.B.3
-
170
-
-
58149308844
-
Altered lipid metabolism in brain injury and disorders
-
Adibhatla, R.M. and Hatcher, J.F., Altered lipid metabolism in brain injury and disorders. Subcell Biochem 2008; 49: 241-68.
-
(2008)
Subcell Biochem
, vol.49
, pp. 241-268
-
-
Adibhatla, R.M.1
Hatcher, J.F.2
-
171
-
-
79955562491
-
Metabolic syndrome: definitions and controversies
-
Kassi, E., Pervanidou, P., Kaltsas, G., and Chrousos, G., Metabolic syndrome: definitions and controversies. BMC Med 2011; 9: 48.
-
(2011)
BMC Med
, vol.9
, pp. 48
-
-
Kassi, E.1
Pervanidou, P.2
Kaltsas, G.3
Chrousos, G.4
-
172
-
-
80054896120
-
Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study
-
Tan, Z.S., Beiser, A.S., Fox, C.S., Au, R., Himali, J.J., Debette, S., Decarli, C., Vasan, R.S., Wolf, P.A., and Seshadri, S., Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study. Diabetes Care 2011; 34(8): 1766-70.
-
(2011)
Diabetes Care
, vol.34
, Issue.8
, pp. 1766-1770
-
-
Tan, Z.S.1
Beiser, A.S.2
Fox, C.S.3
Au, R.4
Himali, J.J.5
Debette, S.6
Decarli, C.7
Vasan, R.S.8
Wolf, P.A.9
Seshadri, S.10
-
173
-
-
77955286117
-
Visceral fat is associated with lower brain volume in healthy middle-aged adults
-
Debette, S., Beiser, A., Hoffmann, U., Decarli, C., O'Donnell, C.J., Massaro, J.M., Au, R., Himali, J.J., Wolf, P.A., Fox, C.S., and Seshadri, S., Visceral fat is associated with lower brain volume in healthy middle-aged adults. Ann Neurol 2010; 68(2): 136-44.
-
(2010)
Ann Neurol
, vol.68
, Issue.2
, pp. 136-144
-
-
Debette, S.1
Beiser, A.2
Hoffmann, U.3
Decarli, C.4
O'Donnell, C.J.5
Massaro, J.M.6
Au, R.7
Himali, J.J.8
Wolf, P.A.9
Fox, C.S.10
Seshadri, S.11
-
174
-
-
77951245182
-
Metabolic syndrome is associated with learning and recall impairment in middle age
-
Hassenstab, J.J., Sweat, V., Bruehl, H., and Convit, A., Metabolic syndrome is associated with learning and recall impairment in middle age. Dement Geriatr Cogn Disord 2010; 29(4): 356-62.
-
(2010)
Dement Geriatr Cogn Disord
, vol.29
, Issue.4
, pp. 356-362
-
-
Hassenstab, J.J.1
Sweat, V.2
Bruehl, H.3
Convit, A.4
-
175
-
-
77955011739
-
Is insulin resistant brain state a central feature of the metabolic-cognitive syndrome?
-
Frisardi,V., Solfrizzi,V., Capurso, C., Imbimbo, B.P., Vendemiale, G., Seripa, D., Pilotto, A., and Panza, F., Is insulin resistant brain state a central feature of the metabolic-cognitive syndrome? J Alzheimer's Dis 2010; 21(1): 57-63.
-
(2010)
J Alzheimer's Dis
, vol.21
, Issue.1
, pp. 57-63
-
-
Frisardi, V.1
Solfrizzi, V.2
Capurso, C.3
Imbimbo, B.P.4
Vendemiale, G.5
Seripa, D.6
Pilotto, A.7
Panza, F.8
-
176
-
-
84865519631
-
Impact of metabolic syndrome on cognition and brain: a selected reviewof the literature
-
Yates, K.F., Sweat, V., Yau, P.L., Turchiano, M.M., and Convit, A., Impact of metabolic syndrome on cognition and brain: a selected reviewof the literature. Arterioscler Thromb Vasc Biol 2012; 32(9): 2060-7.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, Issue.9
, pp. 2060-2067
-
-
Yates, K.F.1
Sweat, V.2
Yau, P.L.3
Turchiano, M.M.4
Convit, A.5
-
177
-
-
84856046189
-
Insulin is differentially related to cognitive decline and atrophy in Alzheimer's disease and aging
-
Burns, J.M., Honea, R.A., Vidoni, E.D., Hutfles, L.J., Brooks, W.M., and Swerdlow, R.H., Insulin is differentially related to cognitive decline and atrophy in Alzheimer's disease and aging. Biochim Biophys Acta 2012; 1822(3): 333-9.
-
(2012)
Biochim Biophys Acta
, vol.1822
, Issue.3
, pp. 333-339
-
-
Burns, J.M.1
Honea, R.A.2
Vidoni, E.D.3
Hutfles, L.J.4
Brooks, W.M.5
Swerdlow, R.H.6
-
178
-
-
77953835533
-
Intersection between metabolic dysfunction, high fat diet consumption, and brain aging
-
Uranga, R.M., Bruce-Keller, A.J., Morrison, C.D., Fernandez-Kim, S.O., Ebenezer, P.J., Zhang, L., Dasuri, K., and Keller, J.N., Intersection between metabolic dysfunction, high fat diet consumption, and brain aging. J Neurochem 2010; 114(2): 344-61.
-
(2010)
J Neurochem
, vol.114
, Issue.2
, pp. 344-361
-
-
Uranga, R.M.1
Bruce-Keller, A.J.2
Morrison, C.D.3
Fernandez-Kim, S.O.4
Ebenezer, P.J.5
Zhang, L.6
Dasuri, K.7
Keller, J.N.8
-
179
-
-
77954559472
-
Type 2 diabetes, related conditions, in relation and dementia: an opportunity for prevention?
-
Luchsinger, J.A., Type 2 diabetes, related conditions, in relation and dementia: an opportunity for prevention? J Alzheimer's Dis 2010; 20(3): 723-36.
-
(2010)
J Alzheimer's Dis
, vol.20
, Issue.3
, pp. 723-736
-
-
Luchsinger, J.A.1
-
180
-
-
38749152419
-
Evolving trends in nonalcoholic fatty liver disease
-
Delgado, J.S., Evolving trends in nonalcoholic fatty liver disease. Eur J Intern Med 2008; 19(2): 75-82.
-
(2008)
Eur J Intern Med
, vol.19
, Issue.2
, pp. 75-82
-
-
Delgado, J.S.1
-
181
-
-
34147151118
-
Next steps in Alzheimer's disease research: interaction between epidemiology and basic science
-
Launer, L.J., Next steps in Alzheimer's disease research: interaction between epidemiology and basic science. Curr Alzheimer Res 2007; 4(2): 141-3.
-
(2007)
Curr Alzheimer Res
, vol.4
, Issue.2
, pp. 141-143
-
-
Launer, L.J.1
-
182
-
-
34547683485
-
Evaluation and management of obesity-related nonalcoholic fatty liver disease
-
Nugent, C. and Younossi, Z.M., Evaluation and management of obesity-related nonalcoholic fatty liver disease. Nat Clin Pract Gastroenterol Hepatol 2007; 4(8): 432-41.
-
(2007)
Nat Clin Pract Gastroenterol Hepatol
, vol.4
, Issue.8
, pp. 432-441
-
-
Nugent, C.1
Younossi, Z.M.2
-
183
-
-
39649092297
-
Obesity, metabolic syndrome, and type 2 diabetes: inflammatory basis of glucose metabolic disorders
-
Pradhan, A., Obesity, metabolic syndrome, and type 2 diabetes: inflammatory basis of glucose metabolic disorders. Nutr Rev 2007; 65(12 Pt 2): S152-6.
-
(2007)
Nutr Rev
, vol.65
, Issue.12 PART. 2
, pp. S152-S156
-
-
Pradhan, A.1
-
184
-
-
39849099669
-
Non-alcoholic fatty liver disease and the metabolic syndrome: an update
-
Rector, R.S., Thyfault, J.P., Wei, Y., and Ibdah, J.A., Non-alcoholic fatty liver disease and the metabolic syndrome: an update. World J Gastroenterol 2008; 14(2): 185-92.
-
(2008)
World J Gastroenterol
, vol.14
, Issue.2
, pp. 185-192
-
-
Rector, R.S.1
Thyfault, J.P.2
Wei, Y.3
Ibdah, J.A.4
-
185
-
-
0014355386
-
Nitrosamine-induced carcinogenesis
-
Swann, P.F. and Magee, P.N., Nitrosamine-induced carcinogenesis. The alklylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate. Biochem J 1968; 110(1): 39-47.
-
(1968)
The alklylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate. Biochem J
, vol.110
, Issue.1
, pp. 39-47
-
-
Swann, P.F.1
Magee, P.N.2
-
186
-
-
0036273095
-
A chemical perspective on the interplay between NO, reactive oxygen species, and reactive nitrogen oxide species
-
Espey, M.G., Miranda, K.M., Thomas, D.D., Xavier, S., Citrin, D., Vitek, M.P., andWink, D.A., A chemical perspective on the interplay between NO, reactive oxygen species, and reactive nitrogen oxide species. Ann N Y Acad Sci 2002; 962: 195-206.
-
(2002)
Ann N Y Acad Sci.
, vol.962
, pp. 195-206
-
-
Espey, M.G.1
Miranda, K.M.2
Thomas, D.D.3
Xavier, S.4
Citrin, D.5
Vitek, M.P.6
Wink, D.A.7
-
188
-
-
23044442730
-
The clinical and biological relationship between Type II diabetes mellitus and Alzheimer's disease
-
Nicolls, M.R., The clinical and biological relationship between Type II diabetes mellitus and Alzheimer's disease. Curr Alzheimer Res 2004; 1(1): 47-54.
-
(2004)
Curr Alzheimer Res
, vol.1
, Issue.1
, pp. 47-54
-
-
Nicolls, M.R.1
-
189
-
-
34447633011
-
Update on non-alcoholic fatty liver disease in children
-
Papandreou, D., Rousso, I., and Mavromichalis, I., Update on non-alcoholic fatty liver disease in children. Clin Nutr 2007; 26(4): 409-15.
-
(2007)
Clin Nutr.
, vol.26
, Issue.4
, pp. 409-415
-
-
Papandreou, D.1
Rousso, I.2
Mavromichalis, I.3
-
190
-
-
34249792393
-
Role of mitochondria in non-alcoholic fatty liver disease
-
Pessayre, D., Role of mitochondria in non-alcoholic fatty liver disease. J Gastroenterol Hepatol 2007; 22 Suppl 1: S20-7.
-
(2007)
J Gastroenterol Hepatol
, vol.22
, Issue.1
, pp. 20-27
-
-
Pessayre, D.1
-
191
-
-
39849091969
-
-
Wei, Y., Rector, R.S., Thyfault, J.P., and Ibdah, J.A., Nonalcoholic fatty liver disease and mitochondrial dysfunction.World J Gastroenterol 2008; 14(2): 193-9.
-
(2008)
Nonalcoholic fatty liver disease and mitochondrial dysfunction.World J Gastroenterol
, vol.14
, Issue.2
, pp. 193-199
-
-
Wei, Y.1
Rector, R.S.2
Thyfault, J.P.3
Ibdah, J.A.4
-
192
-
-
36249009634
-
Pathology of nonalcoholic fatty liver disease
-
Yeh, M.M. and Brunt, E.M., Pathology of nonalcoholic fatty liver disease. Am J Clin Pathol 2007; 128(5): 837-47.
-
(2007)
Am J Clin Pathol
, vol.128
, Issue.5
, pp. 837-847
-
-
Yeh, M.M.1
Brunt, E.M.2
-
193
-
-
0016857569
-
Studies on the mechanism of the diabetogenic activity of streptozotocin and on the ability of compounds to block the diabetogenic activity of streptozotocin (author's transl)
-
Doi, K., [Studies on the mechanism of the diabetogenic activity of streptozotocin and on the ability of compounds to block the diabetogenic activity of streptozotocin (author's transl)]. Nippon Naibunpi Gakkai Zasshi 1975; 51(3): 129-47.
-
(1975)
Nippon Naibunpi Gakkai Zasshi
, vol.51
, Issue.3
, pp. 129-147
-
-
Doi, K.1
-
194
-
-
0035691617
-
The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas
-
Szkudelski, T., The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 2001; 50(6): 537-46.
-
(2001)
Physiol Res
, vol.50
, Issue.6
, pp. 537-546
-
-
Szkudelski, T.1
-
195
-
-
0033460182
-
Damaged neuronal energy metabolism and behavior are improved by Ginkgo biloba extract (EGb 761)
-
Hoyer, S., Lannert, H., Noldner, M., and Chatterjee, S.S., Damaged neuronal energy metabolism and behavior are improved by Ginkgo biloba extract (EGb 761). J Neural Transm 1999; 106(11-12): 1171-88.
-
(1999)
J Neural Transm
, vol.106
, Issue.11-12
, pp. 1171-1188
-
-
Hoyer, S.1
Lannert, H.2
Noldner, M.3
Chatterjee, S.S.4
-
196
-
-
33845655596
-
High sensitivity of fatty liver Shionogi (FLS) mice to diethylnitrosamine hepatocarcinogenesis: comparison to C3H and C57 mice
-
Iwai, S., Murai, T., Makino, S., Min, W., Morimura, K., Mori, S., Hagihara, A., Seki, S., and Fukushima, S., High sensitivity of fatty liver Shionogi (FLS) mice to diethylnitrosamine hepatocarcinogenesis: comparison to C3H and C57 mice. Cancer Lett 2007; 246(1-2): 115-21.
-
(2007)
Cancer Lett
, vol.246
, Issue.1-2
, pp. 115-121
-
-
Iwai, S.1
Murai, T.2
Makino, S.3
Min, W.4
Morimura, K.5
Mori, S.6
Hagihara, A.7
Seki, S.8
Fukushima, S.9
-
197
-
-
0017648112
-
Studies of streptozotocininduced insulitis and diabetes
-
Rossini, A.A., Like, A.A., Chick, W.L., Appel, M.C., and Cahill, G.F., Jr., Studies of streptozotocininduced insulitis and diabetes. Proc Natl Acad Sci U S A 1977; 74(6): 2485-9.
-
(1977)
Proc Natl Acad Sci. U S A
, vol.74
, Issue.6
, pp. 2485-2489
-
-
Rossini, A.A.1
Like, A.A.2
Chick, W.L.3
Appel, M.C.4
Cahill, G.F.5
-
198
-
-
0033561597
-
Site-specificDNAmethylation and apoptosis: induction by diabetogenic streptozotocin
-
Murata, M., Takahashi, A., Saito, I., and Kawanishi, S., Site-specificDNAmethylation and apoptosis: induction by diabetogenic streptozotocin. Biochem Pharmacol 1999; 57(8): 881-7.
-
(1999)
Biochem Pharmacol
, vol.57
, Issue.8
, pp. 881-887
-
-
Murata, M.1
Takahashi, A.2
Saito, I.3
Kawanishi, S.4
-
199
-
-
0023820924
-
Enhancement by streptozotocin of O2-radical generation by the xanthine oxidase system of pancreatic beta-cells
-
Nukatsuka, M., Sakurai, H., Yoshimura, Y., Nishida, M., and Kawada, J., Enhancement by streptozotocin of O2-radical generation by the xanthine oxidase system of pancreatic beta-cells. FEBS Lett 1988; 239(2): 295-8.
-
(1988)
FEBS Lett
, vol.239
, Issue.2
, pp. 295-298
-
-
Nukatsuka, M.1
Sakurai, H.2
Yoshimura, Y.3
Nishida, M.4
Kawada, J.5
-
200
-
-
0033994409
-
Radicals and oxidative stress in diabetes
-
West, I.C., Radicals and oxidative stress in diabetes. Diabet Med 2000; 17(3): 171-80.
-
(2000)
Diabet Med
, vol.17
, Issue.3
, pp. 171-180
-
-
West, I.C.1
-
201
-
-
78649337928
-
Metabolic changes in rat brain following intracerebroventricular injections of streptozotocin: a model of sporadic Alzheimer's disease
-
Labak, M., Foniok, T., Kirk, D., Rushforth, D., Tomanek, B., Jasinski, A., and Grieb, P., Metabolic changes in rat brain following intracerebroventricular injections of streptozotocin: a model of sporadic Alzheimer's disease. Acta Neurochir Suppl 2010; 106: 177-81.
-
(2010)
Acta Neurochir Suppl
, vol.106
, pp. 177-181
-
-
Labak, M.1
Foniok, T.2
Kirk, D.3
Rushforth, D.4
Tomanek, B.5
Jasinski, A.6
Grieb, P.7
-
202
-
-
79960555502
-
Metabolic factors in the development of hepatic steatosis and altered mitochondrial gene expression in vivo
-
Wang, S., Kamat, A., Pergola, P., Swamy, A., Tio, F., and Cusi, K., Metabolic factors in the development of hepatic steatosis and altered mitochondrial gene expression in vivo. Metabolism 2011; 60(8): 1090-9.
-
(2011)
Metabolism
, vol.60
, Issue.8
, pp. 1090-1099
-
-
Wang, S.1
Kamat, A.2
Pergola, P.3
Swamy, A.4
Tio, F.5
Cusi, K.6
-
203
-
-
0028170864
-
Desensitization of brain insulin receptor Effect on glucose/ energy and related metabolism
-
Hoyer, S., Muller, D., and Plaschke, K., Desensitization of brain insulin receptor. Effect on glucose/ energy and related metabolism. JNeural Transm Suppl 1994; 44: 259-68.
-
(1994)
JNeural Transm Suppl
, vol.44
, pp. 259-268
-
-
Hoyer, S.1
Muller, D.2
Plaschke, K.3
-
204
-
-
0031797937
-
Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats
-
Lannert, H. and Hoyer, S., Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats. Behav Neurosci 1998; 112(5): 1199-208.
-
(1998)
Behav Neurosci
, vol.112
, Issue.5
, pp. 1199-1208
-
-
Lannert, H.1
Hoyer, S.2
-
205
-
-
77953785058
-
Comparison of single high-dose streptozotocin with partial pancreatectomy combined with low-dose streptozotocin for diabetes induction in rhesus monkeys
-
Jin, X., Zeng, L., He, S., Chen, Y., Tian, B., Mai, G., Yang, G., Wei, L., Zhang, Y., Li, H., Wang, L., Qiao, C., Cheng, J., and Lu, Y., Comparison of single high-dose streptozotocin with partial pancreatectomy combined with low-dose streptozotocin for diabetes induction in rhesus monkeys. Exp Biol Med (Maywood) 2010; 235(7): 877-85.
-
(2010)
Exp Biol Med (Maywood)
, vol.235
, Issue.7
, pp. 877-885
-
-
Jin, X.1
Zeng, L.2
He, S.3
Chen, Y.4
Tian, B.5
Mai, G.6
Yang, G.7
Wei, L.8
Zhang, Y.9
Li, H.10
Wang, L.11
Qiao, C.12
Cheng, J.13
Lu, Y.14
-
206
-
-
0029887466
-
DNA damage induced by seven N-nitroso compounds in primary cultures of human and rat kidney cells
-
Robbiano, L., Mereto, E., Corbu, C., and Brambilla, G., DNA damage induced by seven N-nitroso compounds in primary cultures of human and rat kidney cells. Mutat Res 1996; 368(1): 41-7.
-
(1996)
Mutat Res
, vol.368
, Issue.1
, pp. 41-47
-
-
Robbiano, L.1
Mereto, E.2
Corbu, C.3
Brambilla, G.4
-
207
-
-
77049104064
-
Cigarette smoking is a risk factor for Alzheimer's Disease: an analysis controlling for tobacco industry affiliation
-
Cataldo, J.K., Prochaska, J.J., and Glantz, S.A., Cigarette smoking is a risk factor for Alzheimer's Disease: an analysis controlling for tobacco industry affiliation. J Alzheimer's Dis 2010; 19(2): 465-80.
-
(2010)
J Alzheimer's Dis
, vol.19
, Issue.2
, pp. 465-480
-
-
Cataldo, J.K.1
Prochaska, J.J.2
Glantz, S.A.3
-
208
-
-
77953388335
-
Genetics of Alzheimer disease in the pre-and post-GWAS era
-
Ertekin-Taner, N., Genetics of Alzheimer disease in the pre-and post-GWAS era. Alzheimers Res Ther 2010; 2(1): 3.
-
(2010)
Alzheimers Res Ther
, vol.2
, Issue.1
, pp. 3
-
-
Ertekin-Taner, N.1
-
209
-
-
84855819016
-
The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE
-
Guerreiro, R.J., Gustafson, D.R., and Hardy, J., The genetic architecture of Alzheimer's disease: beyond APP, PSENs and. Neurobiol Aging 2012; 33(3): 437-56.
-
(2012)
Neurobiol Aging
, vol.33
, Issue.3
, pp. 437-456
-
-
Guerreiro, R.J.1
Gustafson, D.R.2
Hardy, J.3
-
210
-
-
78649232442
-
Genetics of Alzheimer disease
-
Bekris, L.M., Yu, C.E., Bird, T.D., and Tsuang, D.W., Genetics of Alzheimer disease. J Geriatr Psychiatry Neurol 2010; 23(4): 213-27.
-
(2010)
J Geriatr Psychiatry Neurol
, vol.23
, Issue.4
, pp. 213-227
-
-
Bekris, L.M.1
Yu, C.E.2
Bird, T.D.3
Tsuang, D.W.4
-
211
-
-
84861123503
-
Applying epigenetics to Alzheimer's disease via the latent early-life associated regulation (LEARn) model
-
Maloney, B., Sambamurti, K., Zawia, N., and Lahiri, D.K., Applying epigenetics to Alzheimer's disease via the latent early-life associated regulation (LEARn) model. Curr Alzheimer Res 2012; 9(5): 589-99.
-
(2012)
Curr Alzheimer Res
, vol.9
, Issue.5
, pp. 589-599
-
-
Maloney, B.1
Sambamurti, K.2
Zawia, N.3
Lahiri, D.K.4
-
212
-
-
75649108560
-
Transgenic mouse models of Alzheimer's disease
-
Elder, G.A., Gama Sosa, M.A., and De Gasperi, R., Transgenic mouse models of Alzheimer's disease. Mt Sinai J Med 2010; 77(1): 69-81.
-
(2010)
Mt Sinai J Med
, vol.77
, Issue.1
, pp. 69-81
-
-
Elder, G.A.1
Gama Sosa, M.A.2
De Gasperi, R.3
-
213
-
-
77950343693
-
Transgenic Mouse Models of Alzheimer's Disease: Behavioral Testing and Considerations, in Methods of behavior analysis in neuroscience
-
J.J.Buccafusco, Editor: Boca Raton (FL)
-
Bryan, K.J., Lee, H., Perry, G., Smith, M.A., and Casadesus, G., Transgenic Mouse Models of Alzheimer's Disease: Behavioral Testing and Considerations, in Methods of behavior analysis in neuroscience. J.J.Buccafusco, Editor 2009: Boca Raton (FL).
-
(2009)
-
-
Bryan, K.J.1
Lee, H.2
Perry, G.3
Smith, M.A.4
Casadesus, G.5
-
214
-
-
80051545194
-
APP transgenic mice: their use and limitations
-
Balducci, C. and Forloni, G., APP transgenic mice: their use and limitations. Neuromolecular Med 2011; 13(2): 117-37.
-
(2011)
Neuromolecular Med
, vol.13
, Issue.2
, pp. 117-137
-
-
Balducci, C.1
Forloni, G.2
-
215
-
-
84862842525
-
Alzheimer's disease and amyloid: culprit or coincidence?
-
Skaper, S.D., Alzheimer's disease and amyloid: culprit or coincidence? Int Rev Neurobiol 2012; 102: 277-316.
-
(2012)
Int Rev Neurobiol
, vol.102
, pp. 277-316
-
-
Skaper, S.D.1
-
216
-
-
0027016043
-
The role of alterations in free radical metabolism in mediating cognitive impairments in Down's syndrome
-
Brugge, K.L., Nichols, S., Delis, D., Saitoh, T., and Truaner, D., The role of alterations in free radical metabolism in mediating cognitive impairments in Down's syndrome. 1992; 62: 190-8.
-
(1992)
EXS
, vol.62
, pp. 190-198
-
-
Brugge, K.L.1
Nichols, S.2
Delis, D.3
Saitoh, T.4
Truaner, D.5
-
217
-
-
0025472547
-
S100 protein and Down syndrome
-
Marks, A. and Allore, R., S100 protein and Down syndrome. Bioessays 1990; 12(8): 381-3.
-
(1990)
Bioessays
, vol.12
, Issue.8
, pp. 381-383
-
-
Marks, A.1
Allore, R.2
-
218
-
-
84859078543
-
Beta-Amyloid carrying the Dutch mutation has diverse effects on calpain-mediated toxicity in hippocampal neurons
-
Nicholson, A.M., Wold, L.A., Walsh, D.M., and Ferreira, A., beta-Amyloid carrying the Dutch mutation has diverse effects on calpain-mediated toxicity in hippocampal neurons. Mol Med 2012; 18: 178-85.
-
(2012)
Mol Med
, vol.18
, pp. 178-185
-
-
Nicholson, A.M.1
Wold, L.A.2
Walsh, D.M.3
Ferreira, A.4
-
219
-
-
78649753680
-
Screening for familial APP mutations in sporadic cerebral amyloid angiopathy
-
Biffi, A., Plourde, A., Shen, Y., Onofrio, R., Smith, E.E., Frosch, M., Prada, C.M., Gusella, J., Greenberg, S.M., and Rosand, J., Screening for familial APP mutations in sporadic cerebral amyloid angiopathy. PLoS One 2010; 5(11): e13949.
-
(2010)
PLoS One
, vol.5
, Issue.11
, pp. e13949
-
-
Biffi, A.1
Plourde, A.2
Shen, Y.3
Onofrio, R.4
Smith, E.E.5
Frosch, M.6
Prada, C.M.7
Gusella, J.8
Greenberg, S.M.9
Rosand, J.10
-
220
-
-
77955452492
-
Hereditary cerebral hemorrhage with amyloidosis associated with the E693K mutation of APP
-
Bugiani, O., Giaccone, G., Rossi, G., Mangieri, M., Capobianco, R., Morbin, M., Mazzoleni, G., Cupidi, C., Marcon, G., Giovagnoli, A., Bizzi, A., Di Fede, G., Puoti, G., Carella, F., Salmaggi, A., Romorini, A., Patruno, G.M., Magoni, M., Padovani, A., and Tagliavini, F., Hereditary cerebral hemorrhage with amyloidosis associated with the E693K mutation of APP. Arch Neurol 2010; 67(8): 987-95.
-
(2010)
Arch Neurol
, vol.67
, Issue.8
, pp. 987-995
-
-
Bugiani, O.1
Giaccone, G.2
Rossi, G.3
Mangieri, M.4
Capobianco, R.5
Morbin, M.6
Mazzoleni, G.7
Cupidi, C.8
Marcon, G.9
Giovagnoli, A.10
Bizzi, A.11
Di Fede, G.12
Puoti, G.13
Carella, F.14
Salmaggi, A.15
Romorini, A.16
Patruno, G.M.17
Magoni, M.18
Padovani, A.19
Tagliavini, F.20
more..
-
221
-
-
79960853499
-
Insights into Alzheimer disease pathogenesis from studies in transgenic animal models
-
Schaeffer, E.L., Figueiro, M., and Gattaz, W.F., Insights into Alzheimer disease pathogenesis from studies in transgenic animal models. Clinics (Sao Paulo) 2011; 66 Suppl 1: 45-54.
-
(2011)
Clinics (Sao Paulo)
, vol.66
, Issue.1
, pp. 45-54
-
-
Schaeffer, E.L.1
Figueiro, M.2
Gattaz, W.F.3
-
222
-
-
44349117318
-
Alzheimer's disease: epidemiology, genetics, and beyond
-
Wang, X.P. and Ding, H.L., Alzheimer's disease: epidemiology, genetics, and beyond. Neurosci Bull 2008; 24(2): 105-9.
-
(2008)
Neurosci Bull
, vol.24
, Issue.2
, pp. 105-109
-
-
Wang, X.P.1
Ding, H.L.2
-
223
-
-
77954976544
-
The pathological cross talk between apolipoprotein E and amyloid-beta peptide in Alzheimer's disease: emerging gene-based therapeutic approaches
-
Iurescia, S., Fioretti, D., Mangialasche, F., and Rinaldi, M., The pathological cross talk between apolipoprotein E and amyloid-beta peptide in Alzheimer's disease: emerging gene-based therapeutic approaches. J Alzheimer's Dis 2010; 21(1): 35-48.
-
(2010)
J Alzheimer's Dis
, vol.21
, Issue.1
, pp. 35-48
-
-
Iurescia, S.1
Fioretti, D.2
Mangialasche, F.3
Rinaldi, M.4
-
224
-
-
84856221835
-
Veerhuis, R., Blankenstein, M.A., and Nielsen, H.M., The effect of amyloid associated proteins on the expression of genes involved in amyloidbeta clearance by adult human astrocytes
-
Mulder, S.D., Veerhuis, R., Blankenstein, M.A., and Nielsen, H.M., The effect of amyloid associated proteins on the expression of genes involved in amyloidbeta clearance by adult human astrocytes. Exp Neurol 2012; 233(1): 373-9.
-
(2012)
Exp Neurol
, vol.233
, Issue.1
, pp. 373-379
-
-
Mulder, S.D.1
-
225
-
-
0042385094
-
Diabetes, Alzheimer's disease and apolipoprotein genotype
-
Messier, C., Diabetes, Alzheimer's disease and apolipoprotein genotype. Exp Gerontol 2003; 38(9): 941-6.
-
(2003)
Exp Gerontol
, vol.38
, Issue.9
, pp. 941-946
-
-
Messier, C.1
-
226
-
-
22544447688
-
APOE, vascular pathology, and the AD brain
-
Yip, A.G., McKee, A.C., Green, R.C., Wells, J., Young, H., Cupples, L.A., and Farrer, L.A., APOE, vascular pathology, and the AD brain. Neurology 2005; 65(2): 259-65.
-
(2005)
Neurology
, vol.65
, Issue.2
, pp. 259-265
-
-
Yip, A.G.1
McKee, A.C.2
Green, R.C.3
Wells, J.4
Young, H.5
Cupples, L.A.6
Farrer, L.A.7
-
227
-
-
78650029989
-
Insulin metabolism and the risk of Alzheimer disease: the Rotterdam Study
-
Schrijvers, E.M., Witteman, J.C., Sijbrands, E.J., Hofman, A., Koudstaal, P.J., and Breteler, M.M., Insulin metabolism and the risk of Alzheimer disease: the Rotterdam Study. Neurology 2010; 75(22): 1982-7.
-
(2010)
Neurology
, vol.75
, Issue.22
, pp. 1982-1987
-
-
Schrijvers, E.M.1
Witteman, J.C.2
Sijbrands, E.J.3
Hofman, A.4
Koudstaal, P.J.5
Breteler, M.M.6
-
228
-
-
77950361951
-
Statin users without an APOE-epsilon4 allele have increased insulin resistance
-
VanFossen, B.T.,Watson, G.S., Baker, L.D., Rhoads, K.W., Cholerton, B.A., Reger, M.A., Plymate, S.R., Schellenberg, G., and Craft, S., Statin users without an APOE-epsilon4 allele have increased insulin resistance. J Alzheimer's Dis 2010; 19(4): 1149-53.
-
(2010)
J Alzheimer's Dis
, vol.19
, Issue.4
, pp. 1149-1153
-
-
VanFossen B.T.Watson, G.S.1
Baker, L.D.2
Rhoads, K.W.3
Cholerton, B.A.4
Reger, M.A.5
Plymate, S.R.6
Schellenberg, G.7
Craft, S.8
-
229
-
-
80755145989
-
Presenilins in synaptic function and disease
-
Ho, A. and Shen, J., Presenilins in synaptic function and disease. Trends Mol Med 2011; 17(11): 617-24.
-
(2011)
Trends Mol Med
, vol.17
, Issue.11
, pp. 617-624
-
-
Ho, A.1
Shen, J.2
-
230
-
-
79960119114
-
Presenilin regulates insulin signaling via a gamma-secretase-independent mechanism
-
Maesako, M., Uemura, K., Kuzuya, A., Sasaki, K., Asada, M., Watanabe, K., Ando, K., Kubota, M., Kihara, T., and Kinoshita, A., Presenilin regulates insulin signaling via a gamma-secretase-independent mechanism. J Biol Chem 2011; 286(28): 25309-16.
-
(2011)
J Biol Chem
, vol.286
, Issue.28
, pp. 25309-16
-
-
Maesako, M.1
Uemura, K.2
Kuzuya, A.3
Sasaki, K.4
Asada, M.5
Watanabe, K.6
Ando, K.7
Kubota, M.8
Kihara, T.9
Kinoshita, A.10
-
231
-
-
84862014676
-
Gain of function by phosphorylation in Presenilin 1-mediated regulation of insulin signaling
-
Maesako, M., Uemura, K., Kuzuya, A., Sasaki, K., Asada, M., Watanabe, K., Ando, K., Kubota, M., Akiyama, H., Takahashi, R., Kihara, T., Shimohama, S., and Kinoshita, A., Gain of function by phosphorylation in Presenilin 1-mediated regulation of insulin signaling. J Neurochem 2012; 121(6): 964-73.
-
(2012)
J Neurochem
, vol.121
, Issue.6
, pp. 964-973
-
-
Maesako, M.1
Uemura, K.2
Kuzuya, A.3
Sasaki, K.4
Asada, M.5
Watanabe, K.6
Ando, K.7
Kubota, M.8
Akiyama, H.9
Takahashi, R.10
Kihara, T.11
Shimohama, S.12
Kinoshita, A.13
-
232
-
-
30644479192
-
Clinical aspects of inflammation in Alzheimer's disease
-
Rosenberg, P.B., Clinical aspects of inflammation in Alzheimer's disease. Int Rev Psychiatry 2005; 17(6): 503-14.
-
(2005)
Int Rev Psychiatry
, vol.17
, Issue.6
, pp. 503-514
-
-
Rosenberg, P.B.1
-
233
-
-
33644516288
-
Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms
-
Sastre, M., Klockgether, T., and Heneka, M.T., Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. Int J Dev Neurosci 2006; 24(2-3): 167-76.
-
(2006)
Int J Dev Neurosci
, vol.24
, Issue.2-3
, pp. 167-176
-
-
Sastre, M.1
Klockgether, T.2
Heneka, M.T.3
-
234
-
-
31644443192
-
Ceramides in insulin resistance and lipotoxicity
-
Summers, S.A., Ceramides in insulin resistance and lipotoxicity. Prog Lipid Res 2006; 45(1): 42-72.
-
(2006)
Prog Lipid Res
, vol.45
, Issue.1
, pp. 42-72
-
-
Summers, S.A.1
-
235
-
-
33947577504
-
Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?
-
Katsel, P., Li, C., and Haroutunian, V., Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease? Neurochemical research 2007; 32(4-5): 845-56.
-
(2007)
Neurochemical research
, vol.32
, Issue.4-5
, pp. 845-856
-
-
Katsel, P.1
Li, C.2
Haroutunian, V.3
-
236
-
-
77957348390
-
Sphingolipids and insulin resistance: the five Ws
-
Summers, S.A., Sphingolipids and insulin resistance: the five Ws. Curr Opin Lipidol 2010; 21(2): 128-35.
-
(2010)
Curr Opin Lipidol
, vol.21
, Issue.2
, pp. 128-135
-
-
Summers, S.A.1
-
237
-
-
38049186666
-
Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes
-
Han, M.S., Park, S.Y., Shinzawa, K., Kim, S., Chung, K.W., Lee, J.H., Kwon, C.H., Lee, K.W., Park, C.K., Chung,W.J., Hwang, J.S., Yan, J.J., Song, D.K., Tsujimoto, Y., and Lee, M.S., Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes. J Lipid Res 2008; 49(1): 84-97.
-
(2008)
J Lipid Res
, vol.49
, Issue.1
, pp. 84-97
-
-
Han, M.S.1
Park, S.Y.2
Shinzawa, K.3
Kim, S.4
Chung, K.W.5
Lee, J.H.6
Kwon, C.H.7
Lee, K.W.8
Park, C.K.9
Chung, W.J.10
Hwang, J.S.11
Yan, J.J.12
Song, D.K.13
Tsujimoto, Y.14
Lee, M.S.15
-
238
-
-
84860493578
-
Lipid mediators of insulin resistance
-
Holland, W.L., Knotts, T.A., Chavez, J.A., Wang, L.P., Hoehn, K.L., and Summers, S.A., Lipid mediators of insulin resistance. Nutr Rev 2007; 65(6 Pt 2): S39-46.
-
(2007)
Nutr Rev
, vol.65
, Issue.6 PART. 2
, pp. S39-46
-
-
Holland, W.L.1
Knotts, T.A.2
Chavez, J.A.3
Wang, L.P.4
Hoehn, K.L.5
Summers, S.A.6
-
239
-
-
79959746261
-
Sphingolipids: agents provocateurs in the pathogenesis of insulin resistance
-
Lipina, C. and Hundal, H.S., Sphingolipids: agents provocateurs in the pathogenesis of insulin resistance. Diabetologia 2011; 54(7): 1596-607.
-
(2011)
Diabetologia
, vol.54
, Issue.7
, pp. 1596-1607
-
-
Lipina, C.1
Hundal, H.S.2
-
240
-
-
77955657267
-
Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing link
-
DeFronzo, R.A., Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009. Diabetologia 2010; 53(7): 1270-87.
-
(2010)
The Claude Bernard Lecture 2009. Diabetologia
, vol.53
, Issue.7
, pp. 1270-1287
-
-
DeFronzo, R.A.1
-
241
-
-
80054870690
-
Obesityassociated insulin resistance in skeletal muscle: role of lipid accumulation and physical inactivity
-
Eckardt, K., Taube, A., and Eckel, J., Obesityassociated insulin resistance in skeletal muscle: role of lipid accumulation and physical inactivity. Rev Endocr Metab Disord 2011; 12(3): 163-72.
-
(2011)
Rev Endocr Metab Disord
, vol.12
, Issue.3
, pp. 163-172
-
-
Eckardt, K.1
Taube, A.2
Eckel, J.3
-
242
-
-
61849185113
-
Intramuscular lipid metabolism, insulin action, and obesity
-
Consitt, L.A., Bell, J.A., and Houmard, J.A., Intramuscular lipid metabolism, insulin action, and obesity. IUBMB Life 2009; 61(1): 47-55.
-
(2009)
IUBMB Life
, vol.61
, Issue.1
, pp. 47-55
-
-
Consitt, L.A.1
Bell, J.A.2
Houmard, J.A.3
-
243
-
-
1542358155
-
Ceramide synthesis and metabolism as a target for cancer therapy
-
Reynolds, C.P., Maurer, B.J., and Kolesnick, R.N., Ceramide synthesis and metabolism as a target for cancer therapy. Cancer Lett 2004; 206(2): 169-80.
-
(2004)
Cancer Lett
, vol.206
, Issue.2
, pp. 169-180
-
-
Reynolds, C.P.1
Maurer, B.J.2
Kolesnick, R.N.3
-
244
-
-
83655165847
-
Lipids and membrane lateral organization
-
Sonnino, S. and Prinetti, A., Lipids and membrane lateral organization. Front Physiol 2010; 1: 153.
-
(2010)
Front Physiol
, vol.1
, pp. 153
-
-
Sonnino, S.1
Prinetti, A.2
-
245
-
-
77951979338
-
Plasma membrane signaling induced by ionizing radiation
-
Corre, I., Niaudet, C., and Paris, F., Plasma membrane signaling induced by ionizing radiation. Mutat Res 2010; 704(1-3): 61-7.
-
(2010)
Mutat Res
, vol.704
, Issue.1-3
, pp. 61-67
-
-
Corre, I.1
Niaudet, C.2
Paris, F.3
-
246
-
-
0035133331
-
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
-
Hajduch, E., Balendran, A., Batty, I.H., Litherland, G.J., Blair, A.S., Downes, C.P., and Hundal, H.S., Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. Diabetologia 2001; 44(2): 173-83.
-
(2001)
Diabetologia
, vol.44
, Issue.2
, pp. 173-183
-
-
Hajduch, E.1
Balendran, A.2
Batty, I.H.3
Litherland, G.J.4
Blair, A.S.5
Downes, C.P.6
Hundal, H.S.7
-
247
-
-
74849118341
-
Lipid rafts as a membrane-organizing principle
-
Lingwood, D. and Simons, K., Lipid rafts as a membrane-organizing principle. Science 2010; 327(5961): 46-50.
-
(2010)
Science
, vol.327
, Issue.5961
, pp. 46-50
-
-
Lingwood, D.1
Simons, K.2
-
248
-
-
33846854374
-
Free fatty acids and insulin resistance
-
Delarue, J. and Magnan, C., Free fatty acids and insulin resistance. Curr Opin Clin Nutr Metab Care 2007; 10(2): 142-8.
-
(2007)
Curr Opin Clin Nutr Metab Care
, vol.10
, Issue.2
, pp. 142-148
-
-
Delarue, J.1
Magnan, C.2
-
249
-
-
0000993166
-
Sphingomyelinases in cell regulation
-
Liu, B., Obeid, L.M., and Hannun, Y.A., Sphingomyelinases in cell regulation. Semin Cell Dev Biol 1997; 8(3): 311-22.
-
(1997)
Semin Cell Dev Biol
, vol.8
, Issue.3
, pp. 311-322
-
-
Liu, B.1
Obeid, L.M.2
Hannun, Y.A.3
-
250
-
-
42649104331
-
The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice
-
Cong, W.N., Tao, R.Y., Tian, J.Y., Liu, G.T., and Ye, F., The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice. Life Sci 2008; 82(19-20): 983-90.
-
(2008)
Life Sci.
, vol.82
, Issue.19-20
, pp. 983-990
-
-
Cong, W.N.1
Tao, R.Y.2
Tian, J.Y.3
Liu, G.T.4
Ye, F.5
-
251
-
-
34547558619
-
Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity
-
Kolak, M., Westerbacka, J., Velagapudi, V.R., Wagsater, D., Yetukuri, L., Makkonen, J., Rissanen, A., Hakkinen, A.M., Lindell, M., Bergholm, R., Hamsten, A., Eriksson, P., Fisher, R.M., Oresic, M., and Yki-Jarvinen, H., Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity. Diabetes 2007; 56(8): 1960-8.
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 1960-1968
-
-
Kolak, M.1
Westerbacka, J.2
Velagapudi, V.R.3
Wagsater, D.4
Yetukuri, L.5
Makkonen, J.6
Rissanen, A.7
Hakkinen, A.M.8
Lindell, M.9
Bergholm, R.10
Hamsten, A.11
Eriksson, P.12
Fisher, R.M.13
Oresic, M.14
Yki-Jarvinen, H.15
-
252
-
-
34250004321
-
Insulinlike growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells
-
Arboleda, G., Huang, T.J., Waters, C., Verkhratsky, A., Fernyhough, P., and Gibson, R.M., Insulinlike growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells. Eur J Neurosci 2007; 25(10): 3030-8.
-
(2007)
Eur J Neurosci.
, vol.25
, Issue.10
, pp. 3030-3038
-
-
Arboleda, G.1
Huang, T.J.2
Waters, C.3
Verkhratsky, A.4
Fernyhough, P.5
Gibson, R.M.6
-
253
-
-
21244442275
-
Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling
-
Chavez, J.A., Holland, W.L., Bar, J., Sandhoff, K., and Summers, S.A., Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling. J Biol Chem 2005; 280(20): 20148-53.
-
(2005)
J Biol Chem
, vol.280
, Issue.20
, pp. 20148-53
-
-
Chavez, J.A.1
Holland, W.L.2
Bar, J.3
Sandhoff, K.4
Summers, S.A.5
-
254
-
-
0033575310
-
Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A Activation is stereospecific and regulated by phosphatidic acid
-
Chalfant, C.E., Kishikawa, K., Mumby, M.C., Kamibayashi, C., Bielawska, A., and Hannun, Y.A., Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid. J Biol Chem 1999; 274(29): 20313-7.
-
(1999)
J Biol Chem
, vol.274
, Issue.29
, pp. 20313-7
-
-
Chalfant, C.E.1
Kishikawa, K.2
Mumby, M.C.3
Kamibayashi, C.4
Bielawska, A.5
Hannun, Y.A.6
-
255
-
-
0036479251
-
Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: implications for growth arrest
-
Bourbon, N.A., Sandirasegarane, L., and Kester, M., Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: implications for growth arrest. J Biol Chem 2002; 277(5): 3286-92.
-
(2002)
J Biol Chem
, vol.277
, Issue.5
, pp. 3286-3292
-
-
Bourbon, N.A.1
Sandirasegarane, L.2
Kester, M.3
-
256
-
-
58149333763
-
Involvement of phosphatidylinositol-3 kinase/ AKT/PKCzeta/ lambda pathway in the effect of palmitate on glucoseinduced insulin secretion
-
Nogueira, T.C., Anhe, G.F., Carvalho, C.R., Curi, R., Bordin, S., and Carpinelli, A.R., Involvement of phosphatidylinositol-3 kinase/ AKT/PKCzeta/ lambda pathway in the effect of palmitate on glucoseinduced insulin secretion. Pancreas 2008; 37(3): 309-15.
-
(2008)
Pancreas
, vol.37
, Issue.3
, pp. 309-315
-
-
Nogueira, T.C.1
Anhe, G.F.2
Carvalho, C.R.3
Curi, R.4
Bordin, S.5
Carpinelli, A.R.6
-
257
-
-
50049121874
-
Regulation and functions of sphingosine kinases in the brain
-
Bryan, L., Kordula, T., Spiegel, S., and Milstien, S., Regulation and functions of sphingosine kinases in the brain. Biochim Biophys Acta 2008; 1781(9): 459-66.
-
(2008)
Biochim Biophys Acta
, vol.1781
, Issue.9
, pp. 459-466
-
-
Bryan, L.1
Kordula, T.2
Spiegel, S.3
Milstien, S.4
-
258
-
-
35048824758
-
Sphingolipid signaling pathways as potential therapeutic targets in gliomas
-
Van Brocklyn, J.R., Sphingolipid signaling pathways as potential therapeutic targets in gliomas. Mini Rev Med Chem 2007; 7(10): 984-90.
-
(2007)
Mini Rev Med Chem
, vol.7
, Issue.10
, pp. 984-990
-
-
Van Brocklyn, J.R.1
-
259
-
-
78049457564
-
Differential regulation of AKT, MAPK and GSK3beta during C2-ceramide-induced neuronal death
-
Arboleda, G., Cardenas, Y., Rodriguez, Y., Morales, L.C., Matheus, L., and Arboleda, H., Differential regulation of AKT, MAPK and GSK3beta during C2-ceramide-induced neuronal death. Neurotoxicology 2010; 31(6): 687-93.
-
(2010)
Neurotoxicology
, vol.31
, Issue.6
, pp. 687-693
-
-
Arboleda, G.1
Cardenas, Y.2
Rodriguez, Y.3
Morales, L.C.4
Matheus, L.5
Arboleda, H.6
-
260
-
-
0037354119
-
Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway
-
Stoica, B.A., Movsesyan, V.A., Lea, P.M.t., and Faden, A.I., Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway. Mol Cell Neurosci 2003; 22(3): 365-82.
-
(2003)
Mol Cell Neurosci
, vol.22
, Issue.3
, pp. 365-382
-
-
Stoica, B.A.1
Movsesyan, V.A.2
Lea, P.M.t.3
Faden, A.I.4
-
261
-
-
40449097575
-
Targeting of PKCzeta and PKB to caveolinenriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide
-
Hajduch, E., Turban, S., Le Liepvre, X., Le Lay, S., Lipina, C., Dimopoulos, N., Dugail, I., and Hundal, H.S., Targeting of PKCzeta and PKB to caveolinenriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide. Biochem J 2008; 410(2): 369-79.
-
(2008)
Biochem J
, vol.410
, Issue.2
, pp. 369-379
-
-
Hajduch, E.1
Turban, S.2
Le Liepvre, X.3
Le Lay, S.4
Lipina, C.5
Dimopoulos, N.6
Dugail, I.7
Hundal, H.S.8
-
262
-
-
84861024264
-
Insulin resistance, ceramide accumulation, and endoplasmic reticulum stress in human chronic alcohol-related liver disease
-
Longato, L., Ripp, K., Setshedi, M., Dostalek, M., Akhlaghi, F., Branda, M., Wands, J.R., and de la Monte, S.M., Insulin resistance, ceramide accumulation, and endoplasmic reticulum stress in human chronic alcohol-related liver disease. Oxid Med Cell Longev 2012; 2012: 479348.
-
(2012)
Oxid Med Cell Longev
, vol.2012
, pp. 479348
-
-
Longato, L.1
Ripp, K.2
Setshedi, M.3
Dostalek, M.4
Akhlaghi, F.5
Branda, M.6
Wands, J.R.7
de la Monte, S.M.8
-
263
-
-
85018959355
-
Insulin resistance, ceramide accumulation, and endoplasmic reticulum stress in experimental chronic alcohol-induced steatohepatitis
-
Ramirez, T., Longato, L., Tong, M., Dostalek, M., Akhalghi, F., Wands, J.R., and de la Monte, S.M., Insulin resistance, ceramide accumulation, and endoplasmic reticulum stress in experimental chronic alcohol-induced steatohepatitis J Gastroenterol Hepatol 2012.
-
(2012)
J Gastroenterol Hepatol
-
-
Ramirez, T.1
Longato, L.2
Tong, M.3
Dostalek, M.4
Akhalghi, F.5
Wands, J.R.6
de la Monte, S.M.7
-
264
-
-
85027940419
-
Lipidomics is providing new insight into the metabolic syndrome and its sequelae
-
Meikle, P.J. and Christopher, M.J., Lipidomics is providing new insight into the metabolic syndrome and its sequelae. Current opinion in lipidology 2011; 22(3): 210-5.
-
(2011)
Current opinion in lipidology
, vol.22
, Issue.3
, pp. 210-215
-
-
Meikle, P.J.1
Christopher, M.J.2
-
265
-
-
84856496197
-
Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease
-
de la Monte, S.M., Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease. Current Alzheimer research 2012; 9: 35-66.
-
(2012)
Current Alzheimer research
, vol.9
, pp. 35-66
-
-
de la Monte, S.M.1
-
266
-
-
77953254984
-
Multi-dimensional mass spectrometry-based shotgun lipidomics and the altered lipids at the mild cognitive impairment stage of Alzheimer's disease
-
Han, X., Multi-dimensional mass spectrometry-based shotgun lipidomics and the altered lipids at the mild cognitive impairment stage of Alzheimer's disease. Biochimica et biophysica acta 2010; 1801(8): 774-83.
-
(2010)
Biochimica et biophysica acta
, vol.1801
, Issue.8
, pp. 774-783
-
-
Han, X.1
-
267
-
-
77956381154
-
Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss
-
Mielke, M.M., Haughey, N.J., Ratnam Bandaru,V.V., Schech, S., Carrick, R., Carlson, M.C., Mori, S., Miller, M.I., Ceritoglu, C., Brown, T., Albert, M., and Lyketsos, C.G., Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss. Alzheimer's & dementia: the journal of the Alzheimer's Association 2010; 6(5): 378-85.
-
(2010)
Alzheimer's & dementia: the journal of the Alzheimer's Association
, vol.6
, Issue.5
, pp. 378-385
-
-
Mielke, M.M.1
Haughey, N.J.2
Ratnam Bandaru, V.V.3
Schech, S.4
Carrick, R.5
Carlson, M.C.6
Mori, S.7
Miller, M.I.8
Ceritoglu, C.9
Brown, T.10
Albert, M.11
Lyketsos, C.G.12
-
268
-
-
81855168404
-
Plasma Sphingomyelins are Associated with Cognitive Progression in Alzheimer's Disease
-
Mielke, M.M., Haughey, N.J., Bandaru, V.V., Weinberg, D.D., Darby, E., Zaidi, N., Pavlik, V., Doody, R.S., and Lyketsos, C.G., Plasma Sphingomyelins are Associated with Cognitive Progression in Alzheimer's Disease. Journal of Alzheimer's disease: JAD 2011; 27(2): 259-69.
-
(2011)
Journal of Alzheimer's disease: JAD
, vol.27
, Issue.2
, pp. 259-269
-
-
Mielke, M.M.1
Haughey, N.J.2
Bandaru, V.V.3
Weinberg, D.D.4
Darby, E.5
Zaidi, N.6
Pavlik, V.7
Doody, R.S.8
Lyketsos, C.G.9
-
269
-
-
33745265189
-
PPARgamma agonists as newtherapeutic agents for the treatment of Alzheimer's disease
-
Landreth, G., PPARgamma agonists as newtherapeutic agents for the treatment of Alzheimer's disease. Exp Neurol 2006; 199(2): 245-8.
-
(2006)
Exp Neurol
, vol.199
, Issue.2
, pp. 245-248
-
-
Landreth, G.1
-
270
-
-
84858859318
-
High fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism
-
Longato, L., Tong, M.,Wands, J.R., and de la Monte, S.M., High fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism. Hepatol Res 2012; 42(4): 412-27.
-
(2012)
Hepatol Res
, vol.42
, Issue.4
, pp. 412-427
-
-
Longato, L.1
Tong M.Wands, J.R.2
de la Monte, S.M.3
-
271
-
-
42649083706
-
Converging roles for sphingolipids and cell stress in the progression of neuro-AIDS
-
Haughey, N.J., Steiner, J., Nath, A., McArthur, J.C., Sacktor, N., Pardo, C., and Bandaru, V.V., Converging roles for sphingolipids and cell stress in the progression of neuro-AIDS. Front Biosci 2008; 13: 5120-30.
-
(2008)
Front Biosci
, vol.13
, pp. 5120-5130
-
-
Haughey, N.J.1
Steiner, J.2
Nath, A.3
McArthur, J.C.4
Sacktor, N.5
Pardo, C.6
Bandaru, V.V.7
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