Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide

Biochemical Journal

Volumn 410, Issue 2, 2008, Pages 369-379

  Hajduch, Eric ^a,b   Turban, Sophie ^c   Le Liepvre, Xavier ^a,b   Le Lay, Soazig ^a,b   Lipina, Christopher ^c   Dimopoulos, Nikolaos ^c   Dugail, Isabelle ^a,b   Hundal, Harinder S ^c  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Caveolin enriched microdomain; Ceramide; Insulin receptor substrate (IRS); Phosphatase and tensin homologue detected on chromosome 10 (PTEN); Protein kinase B (PKB) directed insulin signalling; Protein kinase C (PKC )

Indexed keywords

AMIDES; ANTIBIOTICS; ENZYME ACTIVITY; HORMONES;

CAVEOLIN-ENRICHED MICRODOMAIN; CERAMIDE; INSULIN RECEPTOR SUBSTRATE (IRS);

SIGNAL TRANSDUCTION;

CAVEOLIN; CAVEOLIN 1; CERAMIDE; CHOLESTEROL; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN KINASE C ZETA; INSULIN; PROTEIN KINASE C;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CAVEOLA; CELL FUNCTION; CELL MEMBRANE; CHOLESTEROL METABOLISM; CHROMOSOME 10; CONTROLLED STUDY; CYTOPATHOLOGY; EMBRYO; HUMAN; HUMAN CELL; INHIBITION KINETICS; MALE; MEMBRANE STRUCTURE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ANIMAL; CELL STRAIN 3T3; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; SKELETAL MUSCLE;

MUS;

3T3 CELLS; ADIPOCYTES; ANIMALS; CAVEOLIN 1; CERAMIDES; CHOLESTEROL; ENZYME ACTIVATION; HUMANS; INSULIN; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 40449097575     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070936     Document Type: Article

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