메뉴 건너뛰기




Volumn 24, Issue 2-3, 2006, Pages 167-176

Contribution of inflammatory processes to Alzheimer's disease: Molecular mechanisms

Author keywords

Alzheimer's disease; BACE; Inflammation; NSAIDs; PPAR

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ACETYLSALICYLIC ACID; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CELL NUCLEUS RECEPTOR; CHEMOKINE; CYTOKINE; FLURBIPROFEN; IBUPROFEN; INDOMETACIN; LIGAND; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ANTAGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; PROSTAGLANDIN J2; ROSIGLITAZONE; SULINDAC SULFIDE; TROGLITAZONE;

EID: 33644516288     PISSN: 07365748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2005.11.014     Document Type: Conference Paper
Times cited : (373)

References (122)
  • 1
    • 0037475148 scopus 로고    scopus 로고
    • In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene) malononitrile
    • E.D. Agdeppa, V. Kepe, A. Petri, N. Satyamurthy, J. Liu, S.C. Huang, G.W. Small, G.M. Cole, and J.R. Barrio In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl) (methyl)amino]-2-naphthyl]ethylidene)malononitrile Neuroscience 117 2003 723 730
    • (2003) Neuroscience , vol.117 , pp. 723-730
    • Agdeppa, E.D.1    Kepe, V.2    Petri, A.3    Satyamurthy, N.4    Liu, J.5    Huang, S.C.6    Small, G.W.7    Cole, G.M.8    Barrio, J.R.9
  • 2
    • 0031031312 scopus 로고    scopus 로고
    • Inflammation and Alzheimer's disease: Mechanisms and therapeutic strategies
    • P.S. Aisen Inflammation and Alzheimer's disease: mechanisms and therapeutic strategies Gerontology 43 1997 143 149
    • (1997) Gerontology , vol.43 , pp. 143-149
    • Aisen, P.S.1
  • 3
    • 0037638809 scopus 로고    scopus 로고
    • Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: A randomized controlled trial
    • Alzheimer's Disease Cooperative Study L.J.
    • P.S. Aisen, K.A. Schafer, M. Grundman, E. Pfeiffer, M. Sano, K.L. Davis, M.R. Farlow, S. Jin, R.G. Thomas, L.J. Thal Alzheimer's Disease Cooperative Study Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial JAMA 289 2003 2819 2826
    • (2003) JAMA , vol.289 , pp. 2819-2826
    • Aisen, P.S.1    Schafer, K.A.2    Grundman, M.3    Pfeiffer, E.4    Sano, M.5    Davis, K.L.6    Farlow, M.R.7    Jin, S.8    Thomas, R.G.9    Thal10
  • 5
    • 0034081386 scopus 로고    scopus 로고
    • Lower counts of astroglia and activated microglia in patients with Alzheimer's Disease with regular use of non-steroidal anti-inflammatory drugs
    • I. Alafuzoff, M. Overmyer, S. Helisalmi, and H. Soininen Lower counts of astroglia and activated microglia in patients with Alzheimer's Disease with regular use of non-steroidal anti-inflammatory drugs J. Alzheimers Dis. 2 2000 37 46
    • (2000) J. Alzheimers Dis. , vol.2 , pp. 37-46
    • Alafuzoff, I.1    Overmyer, M.2    Helisalmi, S.3    Soininen, H.4
  • 7
    • 0033029151 scopus 로고    scopus 로고
    • TGF-β(1), regulation of alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: MRNA stabilization
    • F.M. Amara, A. Junaid, R.R. Clough, and B. Liang TGF-β(1), regulation of alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: mRNA stabilization Brain Res. Mol. Brain Re. 71 1999 42 49
    • (1999) Brain Res. Mol. Brain Re. , vol.71 , pp. 42-49
    • Amara, F.M.1    Junaid, A.2    Clough, R.R.3    Liang, B.4
  • 8
    • 0035831189 scopus 로고    scopus 로고
    • β-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology
    • J. Apelt, and R. Schliebs β-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology Brain Res. 894 2001 21 30
    • (2001) Brain Res. , vol.894 , pp. 21-30
    • Apelt, J.1    Schliebs, R.2
  • 9
    • 0037200076 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs stimulate secretion of non-amyloidogenic precursor protein
    • Y. Avramovich, T. Amit, and M.B. Youdim Non-steroidal anti-inflammatory drugs stimulate secretion of non-amyloidogenic precursor protein J. Biol. Chem. 277 2002 31273 31466
    • (2002) J. Biol. Chem. , vol.277 , pp. 31273-31466
    • Avramovich, Y.1    Amit, T.2    Youdim, M.B.3
  • 13
    • 0030610645 scopus 로고    scopus 로고
    • Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein e
    • S.W. Barger, and A.D. Harmon Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E Nature 388 1997 878 881
    • (1997) Nature , vol.388 , pp. 878-881
    • Barger, S.W.1    Harmon, A.D.2
  • 14
    • 8744228195 scopus 로고    scopus 로고
    • Reduced β-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice
    • V. Beglopoulos, X. Sun, C.A. Saura, C.A. Lemere, R.D. Kim, and J. Shen Reduced β-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice J. Biol. Chem. 279 2004 46907 46914
    • (2004) J. Biol. Chem. , vol.279 , pp. 46907-46914
    • Beglopoulos, V.1    Sun, X.2    Saura, C.A.3    Lemere, C.A.4    Kim, R.D.5    Shen, J.6
  • 15
    • 7244242262 scopus 로고    scopus 로고
    • Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein
    • A. Bellucci, A.J. Westwood, E. Ingram, F. Casamenti, M. Goedert, and M.G. Spillantini Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein Am. J. Pathol. 165 2004 1643 1652
    • (2004) Am. J. Pathol. , vol.165 , pp. 1643-1652
    • Bellucci, A.1    Westwood, A.J.2    Ingram, E.3    Casamenti, F.4    Goedert, M.5    Spillantini, M.G.6
  • 18
    • 1842728419 scopus 로고    scopus 로고
    • Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease β-secretase (BACE-1)
    • I. Blasko, R. Beer, M. Bigl, J. Apelt, G. Franz, D. Rudzki, G. Ransmayr, A. Kampfl, and R. Schliebs Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease β-secretase (BACE-1) J. Neural Transm. 111 2004 523 536
    • (2004) J. Neural Transm. , vol.111 , pp. 523-536
    • Blasko, I.1    Beer, R.2    Bigl, M.3    Apelt, J.4    Franz, G.5    Rudzki, D.6    Ransmayr, G.7    Kampfl, A.8    Schliebs, R.9
  • 19
    • 0036326074 scopus 로고    scopus 로고
    • Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease
    • T. Breidert, J. Callebert, M.T. Heneka, G. Landreth, J.M. Launay, and E.C. Hirsch Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease J. Neurochem. 82 2002 615 624
    • (2002) J. Neurochem. , vol.82 , pp. 615-624
    • Breidert, T.1    Callebert, J.2    Heneka, M.T.3    Landreth, G.4    Launay, J.M.5    Hirsch, E.C.6
  • 20
    • 0035936009 scopus 로고    scopus 로고
    • Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease?
    • J.C. Breitner, and P.P. Zandi Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease? N. Engl. J. Med. 345 2001 1567 1568
    • (2001) N. Engl. J. Med. , vol.345 , pp. 1567-1568
    • Breitner, J.C.1    Zandi, P.P.2
  • 21
    • 0042412157 scopus 로고    scopus 로고
    • Polymorphism in the peroxisome proliferator-activated receptor-α gene influences the risk for Alzheimer's disease
    • S. Brune, H. Kolsch, U. Ptok, M. Majores, A. Schulz, R. Schlosser, M.L. Rao, W. Maier, and R. Heun Polymorphism in the peroxisome proliferator-activated receptor-α gene influences the risk for Alzheimer's disease J. Neural Transm. 110 2003 1041 1050
    • (2003) J. Neural Transm. , vol.110 , pp. 1041-1050
    • Brune, S.1    Kolsch, H.2    Ptok, U.3    Majores, M.4    Schulz, A.5    Schlosser, R.6    Rao, M.L.7    Maier, W.8    Heun, R.9
  • 22
    • 18844378852 scopus 로고    scopus 로고
    • Presenilin function and γ-secretase activity
    • A.L. Brunkan, and A.M. Goate Presenilin function and γ-secretase activity J. Neurochem. 3 2005 769 792
    • (2005) J. Neurochem. , vol.3 , pp. 769-792
    • Brunkan, A.L.1    Goate, A.M.2
  • 24
    • 10044225937 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ induces a clearance mechanism for the amyloid-β peptide
    • I.E. Camacho, L. Serneels, K. Spittaels, P. Merchiers, D. Dominguez, and B. De Strooper Peroxisome proliferator-activated receptor-γ induces a clearance mechanism for the amyloid-β peptide J. Neurosci. 24 2004 10908 10917
    • (2004) J. Neurosci. , vol.24 , pp. 10908-10917
    • Camacho, I.E.1    Serneels, L.2    Spittaels, K.3    Merchiers, P.4    Dominguez, D.5    De Strooper, B.6
  • 25
    • 0034651101 scopus 로고    scopus 로고
    • Inflammatory mechanisms in Alzheimer's disease: Inhibition of β-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARγ agonists
    • C.K. Combs, D.E. Johnson, J.C. Karlo, S.B. Cannady, and G.E. Landreth Inflammatory mechanisms in Alzheimer's disease: inhibition of β-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARγ agonists J. Neurosci. 20 2000 558 567
    • (2000) J. Neurosci. , vol.20 , pp. 558-567
    • Combs, C.K.1    Johnson, D.E.2    Karlo, J.C.3    Cannady, S.B.4    Landreth, G.E.5
  • 26
    • 0035866060 scopus 로고    scopus 로고
    • β-Amyloid stimulation of microglia and monocytes results in TNFα-dependent expression of inducible nitric oxide synthase and neuronal apoptosis
    • C.K. Combs, J.C. Karlo, S.C. Kao, and G.E. Landreth β-Amyloid stimulation of microglia and monocytes results in TNFα-dependent expression of inducible nitric oxide synthase and neuronal apoptosis J. Neurosci. 21 2001 1179 1188
    • (2001) J. Neurosci. , vol.21 , pp. 1179-1188
    • Combs, C.K.1    Karlo, J.C.2    Kao, S.C.3    Landreth, G.E.4
  • 27
    • 0037087324 scopus 로고    scopus 로고
    • Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors
    • R. Cunard, M. Ricote, D. DiCampli, D.C. Archer, D.A. Kahn, C.K. Glass, and C.J. Kelly Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors J. Immunol. 168 2002 2795 2802
    • (2002) J. Immunol. , vol.168 , pp. 2795-2802
    • Cunard, R.1    Ricote, M.2    Dicampli, D.3    Archer, D.C.4    Kahn, D.A.5    Glass, C.K.6    Kelly, C.J.7
  • 29
    • 2542431100 scopus 로고    scopus 로고
    • The microglial phagocytic role with specific plaque types in the Alzheimer disease brain
    • M.R. D'Andrea, G.M. Cole, and M.D. Ard The microglial phagocytic role with specific plaque types in the Alzheimer disease brain Neurobiol. Aging 25 2004 675 683
    • (2004) Neurobiol. Aging , vol.25 , pp. 675-683
    • D'Andrea, M.R.1    Cole, G.M.2    Ard, M.D.3
  • 30
    • 0036779687 scopus 로고    scopus 로고
    • Emerging roles of PPARs in inflammation and immunity
    • R.A. Daynes, and D.C. Jones Emerging roles of PPARs in inflammation and immunity Nat. Rev. Immunol. 2 2002 748 759
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 748-759
    • Daynes, R.A.1    Jones, D.C.2
  • 32
    • 0037205154 scopus 로고    scopus 로고
    • Amyloid precursor protein gene disruption attenuates degeneration of substantia nigra compacta neurons following axotomy
    • L.A. DeGiorgio, Y. Shimizu, H.S. Chun, Y.S. Kim, S. Sugama, J.H. Son, T.H. Joh, and B.T. Volpe Amyloid precursor protein gene disruption attenuates degeneration of substantia nigra compacta neurons following axotomy Brain Res. 938 2002 38 44
    • (2002) Brain Res. , vol.938 , pp. 38-44
    • Degiorgio, L.A.1    Shimizu, Y.2    Chun, H.S.3    Kim, Y.S.4    Sugama, S.5    Son, J.H.6    Joh, T.H.7    Volpe, B.T.8
  • 33
    • 0347087323 scopus 로고    scopus 로고
    • Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation
    • T. Dehmer, M.T. Heneka, M. Sastre, J. Dichgans, and J.B. Schulz Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation J. Neurochem. 88 2004 494 501
    • (2004) J. Neurochem. , vol.88 , pp. 494-501
    • Dehmer, T.1    Heneka, M.T.2    Sastre, M.3    Dichgans, J.4    Schulz, J.B.5
  • 34
    • 0036499074 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis
    • A. Diab, C. Deng, J.D. Smith, R.Z. Hussain, B. Phanavanh, A.E. Lovett-Racke, P.D. Drew, and M.K. Racke Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis J. Immunol. 168 2002 2508 2515
    • (2002) J. Immunol. , vol.168 , pp. 2508-2515
    • Diab, A.1    Deng, C.2    Smith, J.D.3    Hussain, R.Z.4    Phanavanh, B.5    Lovett-Racke, A.E.6    Drew, P.D.7    Racke, M.K.8
  • 35
    • 0027354484 scopus 로고
    • Microglia and cytokines in neurological disease, with special reference to AIDs and Alzheimer's disease
    • D.W. Dickson, S.C. Lee, L.A. Mattiace, S.H. Yen, and C. Brosnan Microglia and cytokines in neurological disease, with special reference to AIDs and Alzheimer's disease Glia 7 1993 75 83
    • (1993) Glia , vol.7 , pp. 75-83
    • Dickson, D.W.1    Lee, S.C.2    Mattiace, L.A.3    Yen, S.H.4    Brosnan, C.5
  • 37
    • 0038375640 scopus 로고    scopus 로고
    • Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: Systematic review and meta-analysis of observational studies
    • M. Etminan, S. Gill, and A. Samii Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies BMJ 327 2003 128
    • (2003) BMJ , vol.327 , pp. 128
    • Etminan, M.1    Gill, S.2    Samii, A.3
  • 39
    • 22244458574 scopus 로고    scopus 로고
    • Neuroscience. Brain under surveillance: The microglia patrol
    • L. Fetler, and S. Amigorena Neuroscience. Brain under surveillance: the microglia patrol Science 309 2005 392 393
    • (2005) Science , vol.309 , pp. 392-393
    • Fetler, L.1    Amigorena, S.2
  • 41
    • 24644435506 scopus 로고    scopus 로고
    • Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears β-amyloid in a mouse model of Alzheimer disease
    • D. Frenkel, R. Maron, D.S. Burt, and H.L. Weiner Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears β-amyloid in a mouse model of Alzheimer disease J. Clin. Invest. 115 2005 2423 2433
    • (2005) J. Clin. Invest. , vol.115 , pp. 2423-2433
    • Frenkel, D.1    Maron, R.2    Burt, D.S.3    Weiner, H.L.4
  • 44
    • 0029847076 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells
    • J.M. Gimble, C.E. Robinson, X. Wu, K.A. Kelly, B.R. Rodriguez, S.A. Kliewer, J.M. Lehmann, and D.C. Morris Peroxisome proliferator-activated receptor-γ activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells Mol. Pharmacol. 50 1996 1087 1094
    • (1996) Mol. Pharmacol. , vol.50 , pp. 1087-1094
    • Gimble, J.M.1    Robinson, C.E.2    Wu, X.3    Kelly, K.A.4    Rodriguez, B.R.5    Kliewer, S.A.6    Lehmann, J.M.7    Morris, D.C.8
  • 45
    • 0031983986 scopus 로고    scopus 로고
    • Glial-neuronal interactions in Alzheimer's disease: The potential role of a 'cytokine cycle' in disease progression
    • W.S. Griffin, J.G. Sheng, and M.C. Royston Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression Brain Pathol. 8 1998 65 72
    • (1998) Brain Pathol. , vol.8 , pp. 65-72
    • Griffin, W.S.1    Sheng, J.G.2    Royston, M.C.3
  • 46
    • 0037101616 scopus 로고    scopus 로고
    • Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis
    • J.T. Guo, J. Yu, D. Grass, F.C. de Beer, and M.S. Kindy Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis J. Neurosci. 22 2002 5900 5909
    • (2002) J. Neurosci. , vol.22 , pp. 5900-5909
    • Guo, J.T.1    Yu, J.2    Grass, D.3    De Beer, F.C.4    Kindy, M.S.5
  • 48
    • 0034674567 scopus 로고    scopus 로고
    • Degradation of the peroxisome proliferator-activated receptorγ is linked to ligand-dependent activation
    • S. Hauser, G. Adelmant, P. Sarraf, H.M. Wright, E. Mueller, and B.M. Spiegelman Degradation of the peroxisome proliferator-activated receptorγ is linked to ligand-dependent activation J. Biol. Chem. 275 2000 18527 18533
    • (2000) J. Biol. Chem. , vol.275 , pp. 18527-18533
    • Hauser, S.1    Adelmant, G.2    Sarraf, P.3    Wright, H.M.4    Mueller, E.5    Spiegelman, B.M.6
  • 50
    • 27644595378 scopus 로고    scopus 로고
    • Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice
    • M.T. Heneka, M. Sastre, L. Dumitrescu-Ozimek, I. Dewachter, J. Walter, T. Klockgether, and F. Van Leuven Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice J. Neuroinflamm. 2 2005 22 33
    • (2005) J. Neuroinflamm. , vol.2 , pp. 22-33
    • Heneka, M.T.1    Sastre, M.2    Dumitrescu-Ozimek, L.3    Dewachter, I.4    Walter, J.5    Klockgether, T.6    Van Leuven, F.7
  • 54
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
    • C. Jiang, A.T. Ting, and B. Seed PPAR-γ agonists inhibit production of monocyte inflammatory cytokines Nature 391 1998 82 86
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 55
    • 0028990941 scopus 로고
    • APOE*4-associated Alzheimer's disease risk is modified by α 1-antichymotrypsin polymorphism
    • M.I. Kamboh, D.K. Sanghera, R.E. Ferrell, and S.T. DeKosky APOE*4-associated Alzheimer's disease risk is modified by α 1-antichymotrypsin polymorphism Nat. Genet. 10 1995 486 488
    • (1995) Nat. Genet. , vol.10 , pp. 486-488
    • Kamboh, M.I.1    Sanghera, D.K.2    Ferrell, R.E.3    Dekosky, S.T.4
  • 58
    • 33644519800 scopus 로고    scopus 로고
    • Anti-inflammatory and antiproliferative actions of peroxisome proliferator-activated receptor-γ (PPARγ) agonists on T-lymphocytes in multiple sclerosis patients and healthy controls
    • L. Klotz, S. Schmidt, M. Schmidt, M. Sastre, T. Klockgether, and M.T. Heneka Anti-inflammatory and antiproliferative actions of peroxisome proliferator-activated receptor-γ (PPARγ) agonists on T-lymphocytes in multiple sclerosis patients and healthy controls Mediators Inflamm. 13 2004 61
    • (2004) Mediators Inflamm. , vol.13 , pp. 61
    • Klotz, L.1    Schmidt, S.2    Schmidt, M.3    Sastre, M.4    Klockgether, T.5    Heneka, M.T.6
  • 59
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • G.W. Kreutzberg Microglia: a sensor for pathological events in the CNS Trends Neurosci. 19 1996 312 318
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 60
    • 9244238647 scopus 로고    scopus 로고
    • Transcription suppression of peroxisome proliferator-activated receptor-γ2 gene expression by tumor necrosis factor-α via an inhibition of CCAAT/ enhancer-binding protein delta during the early stage of adipocyte differentiation
    • M. Kudo, A. Sugawara, A. Uruno, K. Takeuchi, and S. Ito Transcription suppression of peroxisome proliferator-activated receptor-γ2 gene expression by tumor necrosis factor-α via an inhibition of CCAAT/ enhancer-binding protein delta during the early stage of adipocyte differentiation Endocrinology 145 2004 4948 4956
    • (2004) Endocrinology , vol.145 , pp. 4948-4956
    • Kudo, M.1    Sugawara, A.2    Uruno, A.3    Takeuchi, K.4    Ito, S.5
  • 62
    • 0035693506 scopus 로고    scopus 로고
    • Anti-inflammatory actions of peroxisome proliferator-activated receptor-γ agonists in Alzheimer's disease
    • G.E. Landreth, and M.T. Heneka Anti-inflammatory actions of peroxisome proliferator-activated receptor-γ agonists in Alzheimer's disease Neurobiol. Aging 22 2001 937 944
    • (2001) Neurobiol. Aging , vol.22 , pp. 937-944
    • Landreth, G.E.1    Heneka, M.T.2
  • 63
    • 0031013395 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs
    • J.M. Lehmann, J.M. Lenhard, B.B. Oliver, G.M. Ringold, and S.A. Kliewer Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs J. Biol. Chem. 272 1997 3406 3410
    • (1997) J. Biol. Chem. , vol.272 , pp. 3406-3410
    • Lehmann, J.M.1    Lenhard, J.M.2    Oliver, B.B.3    Ringold, G.M.4    Kliewer, S.A.5
  • 64
    • 10044223533 scopus 로고    scopus 로고
    • PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis
    • A.C. Li, and C.K. Glass PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis J. Lipid Res. 45 2004 2161 2173
    • (2004) J. Lipid Res. , vol.45 , pp. 2161-2173
    • Li, A.C.1    Glass, C.K.2
  • 65
    • 0033864582 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptorγ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
    • A.C. Li, K.K. Brown, M.J. Silvestre, T.M. Willson, W. Palinski, and C.K. Glass Peroxisome proliferator-activated receptorγ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice J. Clin. Invest. 106 2000 523 531
    • (2000) J. Clin. Invest. , vol.106 , pp. 523-531
    • Li, A.C.1    Brown, K.K.2    Silvestre, M.J.3    Willson, T.M.4    Palinski, W.5    Glass, C.K.6
  • 68
    • 0037215645 scopus 로고    scopus 로고
    • Role of Microglia in inflammation-mediated neurodegenerative diseases: Mechanisms and strategies for therapeutic intervention
    • B. Liu, and J.-S. Hong Role of Microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention JPET 304 2003 1 7
    • (2003) JPET , vol.304 , pp. 1-7
    • Liu, B.1    Hong, J.-S.2
  • 70
    • 0029835410 scopus 로고    scopus 로고
    • Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24Shydroxycholesterol from the brain into the circulation
    • D. Lütjohann, O. Breuer, G. Ahlborg, I. Nennesmo, A. Siden, U. Dicfalusy, and I. Björkhem Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24Shydroxycholesterol from the brain into the circulation Proc. Natl. Acad. Sci. U.S.A. 93 1996 9799 9804
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 9799-9804
    • Lütjohann, D.1    Breuer, O.2    Ahlborg, G.3    Nennesmo, I.4    Siden, A.5    Dicfalusy, U.6    Björkhem, I.7
  • 72
    • 0031900411 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging
    • I.R. Mackenzie, and D.G. Munoz Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging Neurology 50 1998 986 990
    • (1998) Neurology , vol.50 , pp. 986-990
    • MacKenzie, I.R.1    Munoz, D.G.2
  • 74
    • 0035835451 scopus 로고    scopus 로고
    • Association between polymorphism in regulatory region of gene encoding TNFα and risk of Alzheimer disease and vascular dementia: A case-control study
    • S.M. McCusker, M.D. Curran, K.B. Dynan, C.D. McCullagh, D.D. Urquhart, D. Middleton, C.C. Patterson, S.P. Mcllroy, and A.P. Passmore Association between polymorphism in regulatory region of gene encoding TNFα and risk of Alzheimer disease and vascular dementia: a case-control study Lancet 357 2001 436 439
    • (2001) Lancet , vol.357 , pp. 436-439
    • McCusker, S.M.1    Curran, M.D.2    Dynan, K.B.3    McCullagh, C.D.4    Urquhart, D.D.5    Middleton, D.6    Patterson, C.C.7    McLlroy, S.P.8    Passmore, A.P.9
  • 76
    • 0029811901 scopus 로고    scopus 로고
    • Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
    • P.L. McGeer, M. Schulzer, and E.G. McGeer Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies Neurology 47 1996 425 432
    • (1996) Neurology , vol.47 , pp. 425-432
    • McGeer, P.L.1    Schulzer, M.2    McGeer, E.G.3
  • 77
    • 0345118108 scopus 로고    scopus 로고
    • Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS
    • S. Moreno, S. Farioli-Vecchioli, and M.P. Ceru Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS Neuroscience 123 2004 131 145
    • (2004) Neuroscience , vol.123 , pp. 131-145
    • Moreno, S.1    Farioli-Vecchioli, S.2    Ceru, M.P.3
  • 78
    • 19344361883 scopus 로고    scopus 로고
    • Ibuprofen suppresses interleukin-1β induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate β-amyloid (Aβ) pathology in Alzheimer's models
    • T. Morihara, B. Teter, F. Yang, G.P. Lim, S. Boudinot, F.D. Boudinot, S.A. Frautschy, and G.M. Cole Ibuprofen suppresses interleukin-1β induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate β-amyloid (Aβ) pathology in Alzheimer's models Neuropsychopharmacology 30 2005 1111 1120
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1111-1120
    • Morihara, T.1    Teter, B.2    Yang, F.3    Lim, G.P.4    Boudinot, S.5    Boudinot, F.D.6    Frautschy, S.A.7    Cole, G.M.8
  • 79
    • 0037427384 scopus 로고    scopus 로고
    • Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains
    • R.G. Nagele, M.R. D'Andrea, H. Lee, V. Venkataraman, and H.Y. Wang Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains Brain Res. 971 2003 197 209
    • (2003) Brain Res. , vol.971 , pp. 197-209
    • Nagele, R.G.1    D'Andrea, M.R.2    Lee, H.3    Venkataraman, V.4    Wang, H.Y.5
  • 81
    • 0035341427 scopus 로고    scopus 로고
    • Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma
    • M. Niino, K. Iwabuchi, S. Kikuchi, M. Ato, T. Morohashi, A. Ogata, K. Tashiro, and K. Onoe Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma J. Neuroimmunol. 116 2001 40 48
    • (2001) J. Neuroimmunol. , vol.116 , pp. 40-48
    • Niino, M.1    Iwabuchi, K.2    Kikuchi, S.3    Ato, M.4    Morohashi, T.5    Ogata, A.6    Tashiro, K.7    Onoe, K.8
  • 83
    • 0030483709 scopus 로고    scopus 로고
    • Neurochemical studies of Alzheimer's disease
    • A.M. Palmer Neurochemical studies of Alzheimer's disease Neurodegeneration 5 1996 381 391
    • (1996) Neurodegeneration , vol.5 , pp. 381-391
    • Palmer, A.M.1
  • 84
    • 0032914896 scopus 로고    scopus 로고
    • Genetic variation of the inflammatory cytokine IL-6 delays the initial onset, and reduces the risk for sporadic Alzheimer's disease
    • A. Papassotiropoulos, M. Bagli, F. Jessen, T.A. Bayer, W. Maier, M.L. Rao, and R.A. Heun Genetic variation of the inflammatory cytokine IL-6 delays the initial onset, and reduces the risk for sporadic Alzheimer's disease Ann. Neurol. 45 1999 666 668
    • (1999) Ann. Neurol. , vol.45 , pp. 666-668
    • Papassotiropoulos, A.1    Bagli, M.2    Jessen, F.3    Bayer, T.A.4    Maier, W.5    Rao, M.L.6    Heun, R.A.7
  • 85
    • 0025095717 scopus 로고
    • Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease
    • L.S. Perlmutter, E. Barron, and H.C. Chui Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease Neurosci. Lett. 119 1990 32 36
    • (1990) Neurosci. Lett. , vol.119 , pp. 32-36
    • Perlmutter, L.S.1    Barron, E.2    Chui, H.C.3
  • 88
    • 1842367306 scopus 로고    scopus 로고
    • Degradation of amyloid β-protein by a metalloprotease secreted by microglia and other neural and non-neural cells
    • W.Q. Qiu, Z. Ye, D. Kholodenko, P. Seubert, and D.J. Selkoe Degradation of amyloid β-protein by a metalloprotease secreted by microglia and other neural and non-neural cells J. Biol. Chem. 272 1997 6641 6646
    • (1997) J. Biol. Chem. , vol.272 , pp. 6641-6646
    • Qiu, W.Q.1    Ye, Z.2    Kholodenko, D.3    Seubert, P.4    Selkoe, D.J.5
  • 91
    • 0032737858 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor(PPARγ) as a regulator of monocyte/macrophage function
    • M. Ricote, J.T. Huang, J.S. Welch, and C.K. Glass The peroxisome proliferator-activated receptor(PPARγ) as a regulator of monocyte/macrophage function J. Leukoc. Biol. 66 1999 733 739
    • (1999) J. Leukoc. Biol. , vol.66 , pp. 733-739
    • Ricote, M.1    Huang, J.T.2    Welch, J.S.3    Glass, C.K.4
  • 93
    • 0033525735 scopus 로고    scopus 로고
    • Translation of the Alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5′-unstranslated region sequences
    • J.T. Rogers, L.M. Leiter, J. McPhee, C.M. Cahill, S.S. Zhan, and H. Potter Translation of the Alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5′-unstranslated region sequences J. Biol. Chem. 274 1999 6231 6421
    • (1999) J. Biol. Chem. , vol.274 , pp. 6231-6421
    • Rogers, J.T.1    Leiter, L.M.2    McPhee, J.3    Cahill, C.M.4    Zhan, S.S.5    Potter, H.6
  • 94
    • 13244264935 scopus 로고    scopus 로고
    • Alzheimer's disease β-secretase BACE1 is not a neuron-specific enzyme
    • S. Rossner, C. Lange-Dohna, U. Zeitschel, and J.R. Perez-Polo Alzheimer's disease β-secretase BACE1 is not a neuron-specific enzyme J. Neurochem. 92 2005 226 324
    • (2005) J. Neurochem. , vol.92 , pp. 226-324
    • Rossner, S.1    Lange-Dohna, C.2    Zeitschel, U.3    Perez-Polo, J.R.4
  • 95
    • 0242609178 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and peroxisome proliferator- activated receptor-γ agonists modulate immunostimulated processing of amyloid precursor protein through regulation of β-secretase
    • M. Sastre, I. Dewachter, G.E. Landreth, T.M. Willson, T. Klockgether, F. van Leuven, and M.T. Heneka Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-γ agonists modulate immunostimulated processing of amyloid precursor protein through regulation of β-secretase J. Neurosci. 23 2003 9796 9804
    • (2003) J. Neurosci. , vol.23 , pp. 9796-9804
    • Sastre, M.1    Dewachter, I.2    Landreth, G.E.3    Willson, T.M.4    Klockgether, T.5    Van Leuven, F.6    Heneka, M.T.7
  • 97
    • 25144444278 scopus 로고    scopus 로고
    • Influence of peroxisome proliferator-activated receptor gamma gene polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients
    • S. Sauder, H. Kolsch, D. Lutjohann, A. Schulz, K. von Bergmann, W. Maier, and R. Heun Influence of peroxisome proliferator-activated receptor gamma gene polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients J. Neural Transm. 112 2005 1381 1389
    • (2005) J. Neural Transm. , vol.112 , pp. 1381-1389
    • Sauder, S.1    Kolsch, H.2    Lutjohann, D.3    Schulz, A.4    Von Bergmann, K.5    Maier, W.6    Heun, R.7
  • 98
    • 0347987853 scopus 로고    scopus 로고
    • Folding proteins in fatal ways
    • D.J. Selkoe Folding proteins in fatal ways Nature 426 2003 900 904
    • (2003) Nature , vol.426 , pp. 900-904
    • Selkoe, D.J.1
  • 99
    • 13444293174 scopus 로고    scopus 로고
    • Defining molecular targets to prevent Alzheimer disease
    • D.J. Selkoe Defining molecular targets to prevent Alzheimer disease Arch Neurol. 62 2005 192 195
    • (2005) Arch Neurol. , vol.62 , pp. 192-195
    • Selkoe, D.J.1
  • 100
    • 0035704245 scopus 로고    scopus 로고
    • Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease
    • L.M. Sly, R.F. Krzesicki, J.R. Brashler, A.E. Buhl, D.D. McKinley, D.B. Carter, and J.E. Chin Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease Brain Res. Bull. 56 2001 581 588
    • (2001) Brain Res. Bull. , vol.56 , pp. 581-588
    • Sly, L.M.1    Krzesicki, R.F.2    Brashler, J.R.3    Buhl, A.E.4    McKinley, D.D.5    Carter, D.B.6    Chin, J.E.7
  • 101
    • 0030897133 scopus 로고    scopus 로고
    • Risk of Alzheimer's disease and duration of NSAID use
    • W.F. Stewart, C. Kawas, M. Corrada, and E.J. Metter Risk of Alzheimer's disease and duration of NSAID use Neurology 48 1997 626 632
    • (1997) Neurology , vol.48 , pp. 626-632
    • Stewart, W.F.1    Kawas, C.2    Corrada, M.3    Metter, E.J.4
  • 102
    • 9644275598 scopus 로고    scopus 로고
    • Modulation of nuclear factor-κ B activity by indomethacin influences Aβ levels but not Aβ precursor protein metabolism in a model of Alzheimer's disease
    • S. Sung, H. Yang, K. Uryu, E.B. Lee, L. Zhao, D. Shineman, J.Q. Trojanowski, V.M. Lee, and D. Pratico Modulation of nuclear factor-κ B activity by indomethacin influences Aβ levels but not Aβ precursor protein metabolism in a model of Alzheimer's disease Am. J. Pathol. 165 2004 2197 2206
    • (2004) Am. J. Pathol. , vol.165 , pp. 2197-2206
    • Sung, S.1    Yang, H.2    Uryu, K.3    Lee, E.B.4    Zhao, L.5    Shineman, D.6    Trojanowski, J.Q.7    Lee, V.M.8    Pratico, D.9
  • 106
    • 0033579382 scopus 로고    scopus 로고
    • Microglial activation resulting from CD40-CD40L interaction after β-amyloid
    • J. Tan, T. Town, and D. Paris Microglial activation resulting from CD40-CD40L interaction after β-amyloid Science 286 1999 2352 2355
    • (1999) Science , vol.286 , pp. 2352-2355
    • Tan, J.1    Town, T.2    Paris, D.3
  • 107
    • 0033060675 scopus 로고    scopus 로고
    • Down regulation of peroxisome proliferator-activated receptorgamma expression by inflammatory cytokines and its reversal by thiazolidinediones
    • T. Tanaka, H. Itoh, K. Doi, Y. Fukunaga, K. Hosoda, M. Shintani, J. Yamashita, T.H. Chun, M. Inoue, and K. Masatsugu Down regulation of peroxisome proliferator-activated receptorgamma expression by inflammatory cytokines and its reversal by thiazolidinediones Diabetologia 42 1999 702 710
    • (1999) Diabetologia , vol.42 , pp. 702-710
    • Tanaka, T.1    Itoh, H.2    Doi, K.3    Fukunaga, Y.4    Hosoda, K.5    Shintani, M.6    Yamashita, J.7    Chun, T.H.8    Inoue, M.9    Masatsugu, K.10
  • 108
    • 0035968743 scopus 로고    scopus 로고
    • Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-beta aggregation
    • T. Thomas, T.G. Nadackal, and K. Thomas Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-beta aggregation Neuroreport 12 2001 3263 3267
    • (2001) Neuroreport , vol.12 , pp. 3263-3267
    • Thomas, T.1    Nadackal, T.G.2    Thomas, K.3
  • 109
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
    • P. Tontonoz, E. Hu, and B.M. Spiegelman Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor Cell 79 1994 1147 1156
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 110
    • 0026541591 scopus 로고
    • The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene
    • J.D. Tugwood, I. Issemann, R.G. Anderson, K.R. Bundell, W.L. McPheat, and S. Green The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene EMBO J. 11 1992 433 439
    • (1992) EMBO J. , vol.11 , pp. 433-439
    • Tugwood, J.D.1    Issemann, I.2    Anderson, R.G.3    Bundell, K.R.4    McPheat, W.L.5    Green, S.6
  • 111
    • 5344277556 scopus 로고    scopus 로고
    • Deciphering the molecular basis of memory failure in Alzheimer's disease
    • D.M. Walsh, and D.J. Selkoe Deciphering the molecular basis of memory failure in Alzheimer's disease Neuron 44 2004 181 193
    • (2004) Neuron , vol.44 , pp. 181-193
    • Walsh, D.M.1    Selkoe, D.J.2
  • 112
    • 0035477333 scopus 로고    scopus 로고
    • The cell biology of Alzheimer's disease: Uncovering the secrets of secretases
    • J. Walter, C. Kaether, H. Steiner, and C. Haass The cell biology of Alzheimer's disease: uncovering the secrets of secretases Curr. Opin. Neurobiol. 11 2001 585 590
    • (2001) Curr. Opin. Neurobiol. , vol.11 , pp. 585-590
    • Walter, J.1    Kaether, C.2    Steiner, H.3    Haass, C.4
  • 114
    • 0042904882 scopus 로고    scopus 로고
    • Aß42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein and ErbB-4 receptor and signaling through the APP intracellular domain
    • S. Weggen, J.L. Eriksen, S.A. Sagi, C.U. Pietrzik, T.E. Golde, and E.H. Koo Aß42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein and ErbB-4 receptor and signaling through the APP intracellular domain J. Biol. Chem. 278 2003 30748 30754
    • (2003) J. Biol. Chem. , vol.278 , pp. 30748-30754
    • Weggen, S.1    Eriksen, J.L.2    Sagi, S.A.3    Pietrzik, C.U.4    Golde, T.E.5    Koo, E.H.6
  • 115
    • 0037180823 scopus 로고    scopus 로고
    • Inflammation and therapeutic vaccination in CNS diseases
    • H.L. Weiner, and D.J. Selkoe Inflammation and therapeutic vaccination in CNS diseases Nature 420 2002 879 884
    • (2002) Nature , vol.420 , pp. 879-884
    • Weiner, H.L.1    Selkoe, D.J.2
  • 116
    • 0019410162 scopus 로고
    • Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis
    • P.J. Whitehouse, D.L. Price, A.W. Clark, J.T. Coyle, and M.R. DeLong Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis Ann. Neurol. 10 1981 122 126
    • (1981) Ann. Neurol. , vol.10 , pp. 122-126
    • Whitehouse, P.J.1    Price, D.L.2    Clark, A.W.3    Coyle, J.T.4    Delong, M.R.5
  • 117
  • 121
    • 0030972203 scopus 로고    scopus 로고
    • TNF α-mediated inhibition and reversal of adipocyte differentiation is accompanied by suppressed expression of PPARγ without effects on Pref-1 expression
    • H. Xing, J.P. Northrop, J.R. Grove, K.E. Kilpatric, J-L. Su, and G.M. Ringold TNF α-mediated inhibition and reversal of adipocyte differentiation is accompanied by suppressed expression of PPARγ without effects on Pref-1 expression Endocrinology 138 1997 2776 2783
    • (1997) Endocrinology , vol.138 , pp. 2776-2783
    • Xing, H.1    Northrop, J.P.2    Grove, J.R.3    Kilpatric, K.E.4    Su, J.-L.5    Ringold, G.M.6
  • 122
    • 0041921071 scopus 로고    scopus 로고
    • Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease
    • Q. Yan, J. Zhang, H. Liu, S. Babu-Khan, R. Vassar, A.L. Biere, M. Citron, and G. Landreth Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease J. Neurosci. 23 2003 7504 7509
    • (2003) J. Neurosci. , vol.23 , pp. 7504-7509
    • Yan, Q.1    Zhang, J.2    Liu, H.3    Babu-Khan, S.4    Vassar, R.5    Biere, A.L.6    Citron, M.7    Landreth, G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.