Si-RNA inhibition of brain insulin or insulin-like growth factor receptors causes developmental cerebellar abnormalities: Relevance to fetal alcohol spectrum disorder

Molecular Brain

Volumn 4, Issue 1, 2011, Pages

  De La Monte, Suzanne M ^a,b,c,d   Tong, Ming ^b,c   Bowling, Nathaniel ^c   Moskal, Peter ^c  

^a RHODE ISLAND HOSPITAL   (United States)

^b Liver Research Center Brown University Medical School   (United States)

^c BROWN UNIVERSITY   (United States)

^d BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CHOLINE ACETYLTRANSFERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INSULIN; INSULIN RECEPTOR; NEUROTROPHIN; NEUROTROPHIN 3; NEUROTROPHIN RECEPTOR; PHOSPHO TAU PROTEIN; PROTEIN; SMALL INTERFERING RNA; SOMATOMEDIN B RECEPTOR; SOMATOMEDIN C RECEPTOR; TAU PROTEIN; UNCLASSIFIED DRUG; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; SOMATOMEDIN B; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DEVELOPMENT; BRAIN FUNCTION; BRAIN LEVEL; BRAIN MALFORMATION; CEREBELLUM DISEASE; CEREBELLUM HYPOFOLIATION; CEREBELLUM HYPOPLASIA; CEREBELLUM HYPOTROPHY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FETAL ALCOHOL SYNDROME; GENE EXPRESSION; HISTOPATHOLOGY; HORMONE INHIBITION; MOTOR PERFORMANCE; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROTAROD TEST; ANIMAL; BRAIN; CEREBELLUM; CONGENITAL MALFORMATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; LONG EVANS RAT; METABOLISM; MOTOR ACTIVITY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY;

RATTUS;

ANIMALS; BRAIN; CEREBELLUM; CHOLINE O-ACETYLTRANSFERASE; FEMALE; FETAL ALCOHOL SYNDROME; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (PHOSPHORYLATING); INJECTIONS, INTRAVENTRICULAR; INSULIN; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; MOTOR ACTIVITY; NERVE GROWTH FACTORS; PREGNANCY; RATS; RATS, LONG-EVANS; RECEPTOR, IGF TYPE 1; RECEPTOR, IGF TYPE 2; RECEPTOR, INSULIN; RECEPTORS, NERVE GROWTH FACTOR; RNA, SMALL INTERFERING; TAU PROTEINS;

EID: 79953088080     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/1756-6606-4-13     Document Type: Article

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