Transient hypoxia causes Alzheimer-type molecular and biochemical abnormalities in cortical neurons: Potential strategies for neuroprotection

Journal of Alzheimer's Disease

Volumn 5, Issue 3, 2003, Pages 209-228

  Chen, Guo Jun ^a   Xu, Julia ^a   Lahousse, Stephanie A ^a   Caggiano, Niki L ^a   De la Monte, Suzanne M ^a,b  

^a BROWN UNIVERSITY   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

Author keywords

Amyloid; DNA damage; In vitro neurodegeneration model; Kinase inhibitors; Microtubule associated proteins; Mitochondria; Neuronal death; Sporadic Alzheimer's disease

Indexed keywords

ACETYLCYSTEINE; AMYLOID BETA PROTEIN; CYCLIN DEPENDENT KINASE 5; CYTOSKELETON PROTEIN; ENZYME INHIBITOR; GAMMA SECRETASE; GLUTATHIONE; GLYCOGEN SYNTHASE KINASE 3BETA; MICROTUBULE ASSOCIATED PROTEIN 5; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHOPROTEIN; PRESENILIN 1; REACTIVE OXYGEN METABOLITE; TAU PROTEIN; UBIQUITIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL VIABILITY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; EMBRYO; ENZYME ACTIVATION; GENE MUTATION; HYPOXIA; IMMUNOREACTIVITY; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT;

EID: 0142042435     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2003-5305     Document Type: Article

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