Cerebrovascular pathology contributes to the heterogeneity of Alzheimer's disease

Journal of Alzheimer's Disease

Volumn 1, Issue 2, 1998, Pages 119-134

  Etiene, D ^a   Kraft, J ^a   Ganju, N ^a   Gomez Isla, T ^a   Gemelli, B ^a   Hyman, B T ^a   Hedley Whyte, E T ^a   Wands, J R ^a   De la Monte, S M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Alzheimer's disease; Apolipoprotein E; A amyloid; Cerebral infarction; Multi infarct dementia

Indexed keywords

AMYLOID; APOLIPOPROTEIN E;

ALLELE; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BRAIN INFARCTION; CONTROLLED STUDY; GENOTYPE; HUMAN; HUMAN TISSUE; NEUROFIBRILLARY TANGLE; PREVALENCE; PRIORITY JOURNAL; SENILE PLAQUE;

EID: 0032229658     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-1998-1205     Document Type: Article

References (70)

1. About the presence of paired helical filaments in dystrophic neurites participating in palque formation
2. Apolipoprotein E type epsilon4 allele, heritability and age at onset in twins with Alzheimer disease and vascular dementia
3. Apo E allele frequencies in Alzheimer's disease, Lewy body dementia, Alzheimer's disease with cerebrovascular disease and vascular dementia
4. Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: A third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques
5. Apolipoprotein E genotype, Alzheimer's pathologies and related gene expression in the aged population
6. Gene dosage of apolipoprotein E type 4 allele and the risk for Alzheimer's in late onset families
7. Pathological markers associated with normal aging and dementia in the elderly
8. Quantitation of cerebral atrophy in preclinical and end-stage Alzheimer's disease
9. Aberrant GAP-43 gene expression in Alzheimer's disease
10. Correlates of aberrant neurofilament immunoreactivity in neurodegenerative diseases
11. Impaired brain microcirculation may trigger Alzheimer's disease
12. Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity
13. Hippocampal sclerosis: A common pathological feature of dementia in very old (> or = 80 years of age) humans
14. Neuropathologicai assessment of the lesions of significance in vascular dementia
15. Quantitative analysis of senile plaques in Alzheimer disease: Observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome)
16. Confirmation of the epsilon 4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease
17. Computed tomography in the detection of the vascular component in dementia
18. The apolipoprotein E epsilon 4 allele does not influence the clinical expression of the amyloid precursor protein gene codon 693 or 692 mutations
19. Effectiveness of brief infusions with Ginkgo biloba Special Extract EGb 761 in dementia of the vascular and Alzheimer type
20. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hha1
21. Ginkgo biloba special extract EGb 761 - An anti-dementia drug
22. Massive somatodendritic sprouting of cortical neurons in Alzheimer's disease
23. Neuropathological diagnoses in elderly patients in Oslo: Alzheimer's disease, Lewy body disease, vascular lesions
24. Apolipoprotein E alleles and brain vascular pathology in Alzheimer's disease
25. Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia Of the Alzheimer type or multi-infarct dementia
26. Leuko-araiosis and cerebral hypoperfusion compared in elderly normals and Alzheimer's dementia
27. Diagnosis of Aizheimer's disease
28. The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice
29. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group
30. Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: A quantitative study of visual and auditory cortices
31. Serum autoantibodies in patients with Alzheimer's disease and vascular dementia and in nondemented control subjects
32. Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus
33. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
34. The apolipoprotein e4 allele in patients with Alzheimer's disease
35. Neuritic pathology and dementia in Alzheimer's disease
36. The consortium to establish a registry for Alzheimer's disease (CERAD). II. Standardization of the neuropathological assessment of Alzheimer's disease
37. Misery perfusion with preserved vascular reactivity in Alzheimer's disease
38. The effects of additional pathology on the cognitive deficit in Alzheimer disease
39. Apolipoprotein E genotype and Alzheimer's disease
40. Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension
41. Apolipoprotein-E genotype in normal aging, age-associated memory impairment, Alzheiraer's disease and vascular dementia patients
42. Cognitive impairment and cellular/vascular changes in the cerebral white matter
43. Why are stroke patients prone to develop dementia?
44. Differential eXpreSsion of TGF-beta 1, 2 and 3 isotypes in Alzheimer's disease: A comparative immunohistochemical study with cerebral infarction, aged human and mouse control brains
45. Apolipoprotein E in the genetics and epidemiology of Aizheimer's disease
46. Apolipoprotein E-epsilon4 alleles in cerebral amyioid angiopathy and cerebrovascular pathology associated with Alzheimer's disease
47. Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
48. Dendritic sprouting in Alzheimer's presenile dementia
49. Clinicopathologic study of probable Alzheimer disease: Assessment of criteria for excluding cerebrovascular disease
50. Brain infarction and the clinical expression of Alzheimer disease. The Nun Study
51. Apolipoprotein E: High affinity binding to b/A4 amyloid and increased frequency of type 4 allele in familial Alzheimer's disease
52. Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles
53. In vivo vascular damage, leukocyte activation and inflammatory response induced by beta-amyloid
54. Beta-Amyloid-mediated vasoactivity and vascular endothelial damage
55. Cerebral blood flow and oxygen metabolism in senile dementia of Alzheimer's type and vascular dementia with deep white matter changes
56. Alterations of the blood-brain barrier and glial cells in white- matter lesions in cerebrovascular and Alzheimer's disease patients
57. Regressive changes of astroglia in white matter lesions in cerebrovascular disease and Alzheimer's disease patients
58. APOE-epsilon 4 in patients with Alzheimer disease and vascular dementia
59. Amyloid beta-protein induces the cerebrovascular cellular pathology of Alzheimer's disease and related disorders
60. Multicenter clinicopathological correlation in dementia
61. Apolipoprotein E genotypes and serum lipid levels in Alzheimer's disease and multi-infarct dementia
62. Amyloid angiopathy in diffuse Lewy body disease
63. Expression of V642 APP mutant causes cellular apoptosis as Alzheimer train-linked phenotype
64. Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: The Hisayama Study
65. A case of Alzheimer's disease with extensive focal white matter changes
66. Vascular basement membrane pathology and Alzheimer's disease
67. Plasticity and neurotransmitter receptor changes in Alzheimer's disease and experimental cortical infarcts
68. Association of the apolipoprotein E epsilon 4 allele with clinical subtypes of autopsy-confirmed Alzheimer's disease