-
1
-
-
84856606017
-
Therapeutic targets of brain insulin resistance in sporadic Alzheimer's disease
-
de la Monte SM (2012) Therapeutic targets of brain insulin resistance in sporadic Alzheimer's disease. Front Biosci E4, 1582-1605.
-
(2012)
Front Biosci
, vol.E4
, pp. 1582-1605
-
-
De La Monte, S.M.1
-
2
-
-
70349744089
-
Insulin resistance and neurodegeneration: Roles of obesity, type 2 diabetes mellitus and non-alcoholic steatohepatitis
-
de la Monte SM, Longato L, Tong M, Wands JR (2009) Insulin resistance and neurodegeneration: Roles of obesity, type 2 diabetes mellitus and non-alcoholic steatohepatitis. Curr Opin Investig Drugs 10, 1049-1060.
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 1049-1060
-
-
De La Monte, S.M.1
Longato, L.2
Tong, M.3
Wands, J.R.4
-
3
-
-
33644591150
-
Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetyl-choline
-
Rivera EJ, Goldin A, Fulmer N, Tavares R, Wands JR, de la Monte SM (2005) Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetyl-choline. J Alzheimers Dis 8, 247-268.
-
(2005)
J Alzheimers Dis
, vol.8
, pp. 247-268
-
-
Rivera, E.J.1
Goldin, A.2
Fulmer, N.3
Tavares, R.4
Wands, J.R.5
De La Monte, S.M.6
-
4
-
-
0033064602
-
Effects of insulin on lipid metabolism of larvae and metamorphosing landlocked sea lamprey, Petromyzon marinus
-
DOI 10.1006/gcen.1999.7265
-
Kao Y, Youson JH, Holmes JA, Al-Mahrouki A, Sheridan MA (1999) Effects of insulin on lipid metabolism of larvae and metamorphosing landlocked sea lamprey, Petromyzon marinus. Gen Comp Endocrinol 114, 405-414. (Pubitemid 29256978)
-
(1999)
General and Comparative Endocrinology
, vol.114
, Issue.3
, pp. 405-414
-
-
Kao, Y.-H.1
Youson, J.H.2
Holmes, J.A.3
Al-Mahrouki, A.4
Sheridan, M.A.5
-
5
-
-
45149106053
-
Sphingolipids, insulin resistance, and metabolic disease: New insights from in vivo manipulation of sphingolipid metabolism
-
DOI 10.1210/er.2007-0025
-
Holland WL, Summers SA (2008) Sphingolipids, insulin resistance, and metabolic disease: New insights from in vivo manipulation of sphingolipid metabolism. Endocr Rev 29, 381-402. (Pubitemid 351831506)
-
(2008)
Endocrine Reviews
, vol.29
, Issue.4
, pp. 381-402
-
-
Holland, W.L.1
Summers, S.A.2
-
6
-
-
67349130083
-
Glycosphingolipids and insulin resistance
-
Langeveld M, Aerts JM (2009) Glycosphingolipids and insulin resistance. Prog Lipid Res 48, 196-250.
-
(2009)
Prog Lipid Res
, vol.48
, pp. 196-250
-
-
Langeveld, M.1
Aerts, J.M.2
-
7
-
-
43249083481
-
Free fatty acids and skeletal muscle insulin resistance
-
DOI 10.1097/01.mol.0000319118.44995.9a, PII 0004143320080600000004
-
Kraegen EW, Cooney GJ (2008) Free fatty acids and skeletal muscle insulin resistance. Curr Opin Lipidol 19, 235-241. (Pubitemid 351653560)
-
(2008)
Current Opinion in Lipidology
, vol.19
, Issue.3
, pp. 235-241
-
-
Kraegen, E.W.1
Cooney, G.J.2
-
9
-
-
1542358155
-
Ceramide synthesis and metabolism as a target for cancer therapy
-
DOI 10.1016/j.canlet.2003.08.034, PII S0304383503006360
-
Reynolds CP, Maurer BJ, Kolesnick RN (2004) Ceramide synthesis and metabolism as a target for cancer therapy. Cancer Lett 206, 169-180. (Pubitemid 38317287)
-
(2004)
Cancer Letters
, vol.206
, Issue.2
, pp. 169-180
-
-
Reynolds, C.P.1
Maurer, B.J.2
Kolesnick, R.N.3
-
10
-
-
31644443192
-
Ceramides in insulin resistance and lipo-toxicity
-
Summers SA (2006) Ceramides in insulin resistance and lipo-toxicity. Prog Lipid Res 45, 42-72.
-
(2006)
Prog Lipid Res
, vol.45
, pp. 42-72
-
-
Summers, S.A.1
-
11
-
-
58149144739
-
Sphingolipids: Players in the pathology of metabolic disease
-
Cowart LA (2009) Sphingolipids: Players in the pathology of metabolic disease. Trends Endocrinol Metab 20, 34-42.
-
(2009)
Trends Endocrinol Metab
, vol.20
, pp. 34-42
-
-
Cowart, L.A.1
-
12
-
-
38549152194
-
Principles of bioactive lipid signalling: Lessons from sphingolipids
-
DOI 10.1038/nrm2329, PII NRM2329
-
Hannun YA, Obeid LM (2008) Principles of bioactive lipid signalling: Lessons from sphingolipids. Nat Rev Mol Cell Biol 9, 139-150. (Pubitemid 351158911)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.2
, pp. 139-150
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
13
-
-
0037401894
-
Intracellular signal transduction pathways activated by ceramide and its metabolites
-
DOI 10.1016/S1043-6618(03)00050-1
-
Ruvolo PP (2003) Intracellular signal transduction pathways activated by ceramide and its metabolites. Pharmacol Res 47, 383-392. (Pubitemid 36379200)
-
(2003)
Pharmacological Research
, vol.47
, Issue.5
, pp. 383-392
-
-
Ruvolo, P.P.1
-
14
-
-
0036479251
-
Ceramide-induced inhibition of Akt is mediated through protein kinase Cζ. Implications for growth arrest
-
DOI 10.1074/jbc.M110541200
-
Bourbon NA, Sandirasegarane L, Kester M (2002) Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: Implications for growth arrest. J Biol Chem 277, 3286-3292. (Pubitemid 34953194)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.5
, pp. 3286-3292
-
-
Bourbon, N.A.1
Sandirasegarane, L.2
Kester, M.3
-
15
-
-
0035133331
-
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
-
DOI 10.1007/s001250051596
-
Hajduch E, Balendran A, Batty IH, Litherland GJ, Blair AS, Downes CP, Hundal HS (2001) Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. Diabetologia 44, 173-183. (Pubitemid 32156201)
-
(2001)
Diabetologia
, vol.44
, Issue.2
, pp. 173-183
-
-
Hajduch, E.1
Balendran, A.2
Batty, I.H.3
Litherland, G.J.4
Blair, A.S.5
Downes, C.P.6
Hundal, H.S.7
-
16
-
-
58149333763
-
Involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion
-
Nogueira TC, Anhe GF, Carvalho CR, Curi R, Bordin S, Carpinelli AR (2008) Involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion. Pancreas 37, 309-315.
-
(2008)
Pancreas
, vol.37
, pp. 309-315
-
-
Nogueira, T.C.1
Anhe, G.F.2
Carvalho, C.R.3
Curi, R.4
Bordin, S.5
Carpinelli, A.R.6
-
17
-
-
0142091454
-
Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism
-
DOI 10.1128/MCB.23.21.7794-7808.2003
-
Powell DJ, Hajduch E, Kular G, Hundal HS (2003) Ceramide disables 3-phosphoinositide binding to the pleck-strin homology domain of protein kinase B (PKB) /Akt by a PKCzeta-dependent mechanism. Mol Cell Biol 23, 7794-7808. (Pubitemid 37271476)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.21
, pp. 7794-7808
-
-
Powell, D.J.1
Hajduch, E.2
Kular, G.3
Hundal, H.S.4
-
18
-
-
0038532298
-
A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
-
DOI 10.1074/jbc.M212307200
-
Chavez JA, Knotts TA, Wang LP, Li G, Dobrowsky RT, Florant GL, Summers SA (2003) A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction bysaturated fatty acids. J Biol Chem278, 10297-10303. (Pubitemid 36800291)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.12
, pp. 10297-10303
-
-
Chavez, J.A.1
Knotts, T.A.2
Wang, L.-P.3
Li, G.4
Dobrowsky, R.T.5
Florant, G.L.6
Summers, S.A.7
-
19
-
-
4344614649
-
Regulation of insulin action by ceramide: Dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B
-
DOI 10.1074/jbc.M406499200
-
Stratford S, Hoehn KL, Liu F, Summers SA (2004) Regulation of insulin action by ceramide: Dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B. J Biol Chem 279, 36608-36615. (Pubitemid 39129005)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.35
, pp. 36608-36615
-
-
Stratford, S.1
Hoehn, K.L.2
Liu, F.3
Summers, S.A.4
-
20
-
-
54049150442
-
Molecular mechanisms and therapeutic targets insteatosis and steatohepatitis
-
Anderson N, Borlak J (2008) Molecular mechanisms and therapeutic targets insteatosis and steatohepatitis. Pharmacol Rev 60, 311-357.
-
(2008)
Pharmacol Rev
, vol.60
, pp. 311-357
-
-
Anderson, N.1
Borlak, J.2
-
21
-
-
35948950834
-
Endoplasmic reticulum stress and liver injury
-
DOI 10.1055/s-2007-991513
-
Kaplowitz N, Than TA, Shinohara M, Ji C (2007) Endoplas-mic reticulum stress and liver injury. Semin Liver Dis 27, 367-377. (Pubitemid 350071837)
-
(2007)
Seminars in Liver Disease
, vol.27
, Issue.4
, pp. 367-377
-
-
Kaplowitz, N.1
Tin, A.T.2
Shinohara, M.3
Ji, C.4
-
22
-
-
56649094325
-
Molecular mechanisms of lipotox-icity in nonalcoholic fatty liver disease
-
Malhi H, Gores GJ (2008) Molecular mechanisms of lipotox-icity in nonalcoholic fatty liver disease. Semin Liver Dis 28, 360-369.
-
(2008)
Semin Liver Dis
, vol.28
, pp. 360-369
-
-
Malhi, H.1
Gores, G.J.2
-
23
-
-
34249302400
-
Endoplasmic reticulum (ER) stress & diabetes
-
Sundar Rajan S, Srinivasan V, Balasubramanyam M, Tatu U (2007) Endoplasmic reticulum (ER) stress & diabetes. Indian J Med Res 125, 411-424. (Pubitemid 46805455)
-
(2007)
Indian Journal of Medical Research
, vol.125
, Issue.3
, pp. 411-424
-
-
Rajan, S.S.1
Srinivasan, V.2
Balasubramanyam, M.3
Tatu, U.4
-
24
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil GS (2010) Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140, 900-917.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
25
-
-
79952708723
-
Endoplasmic reticulum stress in liver disease
-
Malhi H, Kaufman RJ (2011) Endoplasmic reticulum stress in liver disease. J Hepatol 54, 795-809.
-
(2011)
J Hepatol
, vol.54
, pp. 795-809
-
-
Malhi, H.1
Kaufman, R.J.2
-
26
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
DOI 10.1126/science.1103160
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306, 457-461. (Pubitemid 39372439)
-
(2004)
Science
, vol.306
, Issue.5695
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.-H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Gorgun, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
27
-
-
79955103141
-
The contribution of endo-plasmic reticulum stress to liver diseases
-
Dara L, Ji C, Kaplowitz N (2011) The contribution of endo-plasmic reticulum stress to liver diseases. Hepatology 53, 1752-1763.
-
(2011)
Hepatology
, vol.53
, pp. 1752-1763
-
-
Dara, L.1
Ji, C.2
Kaplowitz, N.3
-
28
-
-
0031302684
-
Staging of Alzheimer-related cortical destruction
-
discussion 269-272
-
Braak H, Braak E (1997) Staging of Alzheimer-related cortical destruction. Int Pychogeriatr 9 (Suppl 1) , 257-261; discussion 269-272.
-
(1997)
Int Pychogeriatr
, vol.9
, Issue.SUPPL. 1
, pp. 257-261
-
-
Braak, H.1
Braak, E.2
-
29
-
-
0345059338
-
Comparison of pathological diagnostic cri- teria for Alzheimer disease
-
Nagy Z, Esiri MM, Joachim C, Jobst KA, Morris JH, King EM, Hindley NJ, McDonald B, Litchfield S, Barnetson L, Smith AD (1998) Comparison of pathological diagnostic cri- teria for Alzheimer disease. Alzheimer Dis Assoc Disords 12, 182-189.
-
(1998)
Alzheimer Dis Assoc Disords
, vol.12
, pp. 182-189
-
-
Nagy, Z.1
Esiri, M.M.2
Joachim, C.3
Jobst, K.A.4
Morris, J.H.5
King, E.M.6
Hindley, N.J.7
McDonald, B.8
Litchfield, S.9
Barnetson, L.10
Smith, A.D.11
-
30
-
-
67649687040
-
Hepatic ceramide may mediate brain insulin resistance and neurodegeneration in type 2 diabetes and non-alcoholic steatohepatitis
-
Lyn-Cook LE Jr, Lawton M, Tong M, Silbermann E, Lon-gato L, Jiao P, Mark P, Wands JR, Xu H, de la Monte SM (2009) Hepatic ceramide may mediate brain insulin resistance and neurodegeneration in type 2 diabetes and non-alcoholic steatohepatitis. J Alzheimers Dis 16, 715-729.
-
(2009)
J Alzheimers Dis
, vol.16
, pp. 715-729
-
-
Lyn-Cook, Jr.L.E.1
Lawton, M.2
Tong, M.3
Silbermann, E.4
Lon-Gato, L.5
Jiao, P.6
Mark, P.7
Wands, J.R.8
Xu, H.9
De La Monte, S.M.10
-
31
-
-
52449087540
-
Limited Alzheimer-type neurodegeneration in experimental obesity and Type 2 diabetes mellitus
-
Moroz N, Tong M, Longato L, Xu H, de la Monte SM (2008) Limited Alzheimer-type neurodegeneration in experimental obesity and Type 2 diabetes mellitus. J Alzheimers Dis 15, 29-44.
-
(2008)
J Alzheimers Dis
, vol.15
, pp. 29-44
-
-
Moroz, N.1
Tong, M.2
Longato, L.3
Xu, H.4
De La Monte, S.M.5
-
32
-
-
79960737448
-
Weight loss amelioration of non-alcoholic steatohepatitis linked to shifts in hepatic ceramide expression and serum ceramide levels
-
Promrat K, Longato L, Wands JR, de la Monte SM (2011) Weight loss amelioration of non-alcoholic steatohepatitis linked to shifts in hepatic ceramide expression and serum ceramide levels. Hepatol Res 41, 754-762.
-
(2011)
Hepatol Res
, vol.41
, pp. 754-762
-
-
Promrat, K.1
Longato, L.2
Wands, J.R.3
De La Monte, S.M.4
-
33
-
-
0842266604
-
Oxidative protein folding in eukaryotes: Mechanisms and consequences
-
DOI 10.1083/jcb.200311055
-
Tu BP, Weissman JS (2004) Oxidative protein folding in eukaryotes: Mechanisms and consequences. J Cell Biol 164, 341-346. (Pubitemid 38174761)
-
(2004)
Journal of Cell Biology
, vol.164
, Issue.3
, pp. 341-346
-
-
Tu, B.P.1
Weissman, J.S.2
-
34
-
-
79953152999
-
Herp regulates Hrd1-mediated ubiquity-lation in a ubiquitin-like domain-dependent manner
-
Kny M, Standera S, Hartmann-Petersen R, Kloetzel PM, Seeger M (2011) Herp regulates Hrd1-mediated ubiquity-lation in a ubiquitin-like domain-dependent manner. J Biol Chem 286, 5151-5156.
-
(2011)
J Biol Chem
, vol.286
, pp. 5151-5156
-
-
Kny, M.1
Standera, S.2
Hartmann-Petersen, R.3
Kloetzel, P.M.4
Seeger, M.5
-
35
-
-
0038182518
-
IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2α signaling
-
DOI 10.1074/jbc.M212074200
-
van Huizen R, Martindale JL, Gorospe M, Holbrook NJ (2003) P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling. J Biol Chem 278, 15558-15564. (Pubitemid 36799663)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.18
, pp. 15558-15564
-
-
Van Huizen, R.1
Martindale, J.L.2
Gorospe, M.3
Holbrook, N.J.4
-
36
-
-
0030478489
-
Membrane components separate early-onset Alzheimer's disease from senile dementia of the Alzheimer type
-
DOI 10.1017/S1041610296002736
-
Gottfries CG, Karlsson I, Svennerholm L (1996) Membrane components separate early-onset Alzheimer's disease from senile dementia of the Alzheimer type. Int Psychogeriatr 8, 365-372. (Pubitemid 27067586)
-
(1996)
International Psychogeriatrics
, vol.8
, Issue.3
, pp. 365-372
-
-
Gottfries, C.-G.1
Karlsson, I.2
Svennerholm, L.3
-
37
-
-
74149083982
-
Deregulation of sphingolipid metabolism in Alzheimer's disease
-
He X, Huang Y, Li B, Gong CX, Schuchman EH (2010) Deregulation of sphingolipid metabolism in Alzheimer's disease. Neurobiol Aging 31, 398-408.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 398-408
-
-
He, X.1
Huang, Y.2
Li, B.3
Gong, C.X.4
Schuchman, E.H.5
-
38
-
-
77953268102
-
Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis
-
Haughey NJ, Bandaru VV, Bae M, Mattson MP (2010) Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis. Biochim Biophys Acta 1801, 878-886.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 878-886
-
-
Haughey, N.J.1
Bandaru, V.V.2
Bae, M.3
Mattson, M.P.4
-
39
-
-
77953254984
-
Multi-dimensional mass spectrometry-based shotgun lipidomics and the altered lipids at the mild cognitive impairment stage of Alzheimer's disease
-
Han X (2010) Multi-dimensional mass spectrometry-based shotgun lipidomics and the altered lipids at the mild cognitive impairment stage of Alzheimer's disease. Biochim Biophys Acta 1801, 774-783.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 774-783
-
-
Han, X.1
-
40
-
-
0036677303
-
Substantialsulfatide deficiency and ceramide elevation in very early Alzheimer's disease: Potential role in disease pathogenesis
-
Han X, M Holtzman D, McKeel DW Jr, Kelley J, Morris JC (2002) Substantialsulfatide deficiency and ceramide elevation in very early Alzheimer's disease: Potential role in disease pathogenesis. J Neurochem 82, 809-818.
-
(2002)
J Neurochem
, vol.82
, pp. 809-818
-
-
Han, X.1
Holtzman D, M.2
McKeel, Jr.D.W.3
Kelley, J.4
Morris, J.C.5
-
41
-
-
38349051098
-
Glucosylceramide syn-thase decrease in frontal cortex of Alzheimer brain correlates with abnormal increase in endogenous ceramides: Consequences to morphology and viability on enzyme suppression in cultured primary neurons
-
Marks N, Berg MJ, Saito M (2008) Glucosylceramide syn-thase decrease in frontal cortex of Alzheimer brain correlates with abnormal increase in endogenous ceramides: Consequences to morphology and viability on enzyme suppression in cultured primary neurons. Brain Res 1191, 136-147.
-
(2008)
Brain Res
, vol.1191
, pp. 136-147
-
-
Marks, N.1
Berg, M.J.2
Saito, M.3
-
42
-
-
33947577504
-
Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: A shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?
-
DOI 10.1007/s11064-007-9297-x
-
Katsel P, Li C, Haroutunian V (2007) Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: A shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease? Neurochem Res 32, 845-856. (Pubitemid 46481322)
-
(2007)
Neurochemical Research
, vol.32
, Issue.4-5
, pp. 845-856
-
-
Katsel, P.1
Li, C.2
Haroutunian, V.3
-
43
-
-
79960798079
-
Mass and relative elution time profiling: Two-dimensional analysis of sphingolipids in Alzheimer's disease brains
-
Hejazi L, Wong JW, Cheng D, Proschogo N, Ebrahimi D, Gar-ner B, Don AS (2011) Mass and relative elution time profiling: Two-dimensional analysis of sphingolipids in Alzheimer's disease brains. Biochemical J 438, 165-175.
-
(2011)
Biochemical J
, vol.438
, pp. 165-175
-
-
Hejazi, L.1
Wong, J.W.2
Cheng, D.3
Proschogo, N.4
Ebrahimi, D.5
Gar-Ner, B.6
Don, A.S.7
-
44
-
-
77953279456
-
Role of amyloid beta in lipid homeostasis
-
Grosgen S, Grimm MO, Friess P, Hartmann T (2010) Role of amyloid beta in lipid homeostasis. Biochim Biophys Acta 1801, 966-974.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 966-974
-
-
Grosgen, S.1
Grimm, M.O.2
Friess, P.3
Hartmann, T.4
-
45
-
-
0037036168
-
Confirmation of association between D10S583 and Alzheimer's disease in a case-control sample
-
DOI 10.1016/S0304-3940(02)00243-4, PII S0304394002002434
-
Ait-Ghezala G, Abdullah L, Crescentini R, Crawford F, Town T, Singh S, Richards D, Duara R, Mullan M (2002) Confirma- tionofassociation between D10S583 and Alzheimer's disease in a case-control sample. Neurosci Lett 325, 87-90. (Pubitemid 34614536)
-
(2002)
Neuroscience Letters
, vol.325
, Issue.2
, pp. 87-90
-
-
Ait-Ghezala, G.1
Abdullah, L.2
Crescentini, R.3
Crawford, F.4
Town, T.5
Singh, S.6
Richards, D.7
Duara, R.8
Mullan, M.9
-
46
-
-
33746565284
-
Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease
-
DOI 10.1038/sj.mp.4001854, PII 4001854
-
Martins IJ, Hone E, Foster JK, Sunram-Lea SI, Gnjec A, Fuller SJ, Nolan D, Gandy SE, Martins RN (2006) Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease. Mol Psychiatry 11, 721-736. (Pubitemid 44141805)
-
(2006)
Molecular Psychiatry
, vol.11
, Issue.8
, pp. 721-736
-
-
Martins, I.J.1
Hone, E.2
Foster, J.K.3
Sunram-Lea, S.I.4
Gnjec, A.5
Fuller, S.J.6
Nolan, D.7
Gandy, S.E.8
Martins, R.N.9
-
47
-
-
61649120841
-
ApoE4 disrupts sterol and sphingolipid metabolism in Alzheimer's but not normal brain
-
Bandaru VV, Troncoso J, Wheeler D, Pletnikova O, Wang J, Conant K, Haughey NJ (2009) ApoE4 disrupts sterol and sphingolipid metabolism in Alzheimer's but not normal brain. Neurobiol Aging 30, 591-599.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 591-599
-
-
Bandaru, V.V.1
Troncoso, J.2
Wheeler, D.3
Pletnikova, O.4
Wang, J.5
Conant, K.6
Haughey, N.J.7
-
48
-
-
33645960672
-
Intracerebral streptozotocin model of type 3 diabetes: Relevance to sporadic Alzheimer's disease
-
Lester-Coll N, Rivera EJ, Soscia SJ, Doiron K, Wands JR, de la Monte SM (2006) Intracerebral streptozotocin model of type 3 diabetes: Relevance to sporadic Alzheimer's disease. J Alzheimers Dis 9, 13-33.
-
(2006)
J Alzheimers Dis
, vol.9
, pp. 13-33
-
-
Lester-Coll, N.1
Rivera, E.J.2
Soscia, S.J.3
Doiron, K.4
Wands, J.R.5
De La Monte, S.M.6
-
49
-
-
76249083449
-
Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment
-
de la Monte SM, Tong M, Lawton M, Longato L (2009) Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment. Mol Neurode-gener 4, 54.
-
(2009)
Mol Neurode-gener
, vol.4
, pp. 54
-
-
De La Monte, S.M.1
Tong, M.2
Lawton, M.3
Longato, L.4
-
50
-
-
77953004836
-
Early limited nitrosamine exposures exacerbate high fat diet-mediated type2 diabetes and neurodegeneration
-
Tong M, Longato L, de la Monte SM (2010) Early limited nitrosamine exposures exacerbate high fat diet-mediated type2 diabetes and neurodegeneration. BMC Endocr Disord 10, 4.
-
(2010)
BMC Endocr Disord
, vol.10
, pp. 4
-
-
Tong, M.1
Longato, L.2
De La Monte, S.M.3
-
51
-
-
68949089312
-
Alzheimer's disease is type 3 diabetes: Evidence reviewed
-
de la Monte SM, Wands JR (2008) Alzheimer's disease is type 3 diabetes: Evidence reviewed. J Diabetes Sci Tech 2, 1101-1113.
-
(2008)
J Diabetes Sci Tech
, vol.2
, pp. 1101-1113
-
-
De La Monte, S.M.1
Wands, J.R.2
-
52
-
-
0028170864
-
Desensitization of brain insulin receptor. Effect on glucose/energy and related metabolism
-
Hoyer S, Muller D, Plaschke K (1994) Desensitization of brain insulin receptor effect on glucose/energy and related metabolism. J Neural Transm Suppl 44, 259-268. (Pubitemid 24372903)
-
(1994)
Journal of Neural Transmission, Supplement
, Issue.44
, pp. 259-268
-
-
Hoyer, S.1
Muller, D.2
Plaschke, K.3
-
53
-
-
0033653771
-
Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease causes and consequences: An update
-
Hoyer S (2000) Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease causes and consequences: An update. Exp Gerontol 35, 1363-1372.
-
(2000)
Exp Gerontol
, vol.35
, pp. 1363-1372
-
-
Hoyer, S.1
-
54
-
-
34147173277
-
Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment
-
DOI 10.2174/156720507780362137
-
Craft S (2007) Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment. Curr Alzheimer Res 4, 147-152. (Pubitemid 46557503)
-
(2007)
Current Alzheimer Research
, vol.4
, Issue.2
, pp. 147-152
-
-
Craft, S.1
-
55
-
-
0037147666
-
Phosphorylation of eukaryotic initiation factor-2α (eIF2α) is associated with neuronal degeneration in Alzheimer's disease
-
DOI 10.1097/00001756-200212200-00011
-
Chang RC, Wong AK, Ng HK, Hugon J (2002) Phospho-rylation of eukaryotic initiation factor-2alpha (eIF2alpha) is associated with neuronal degenerationinAlzheimer's disease. Neuroreport 13, 2429-2432. (Pubitemid 36143538)
-
(2002)
NeuroReport
, vol.13
, Issue.18
, pp. 2429-2432
-
-
Chang, R.C.C.1
Wong, A.K.Y.2
Ng, H.-K.3
Hugon, J.4
-
56
-
-
65349093893
-
The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus
-
Hoozemans JJ, van Haastert ES, Nijholt DA, Rozemuller AJ, Eikelenboom P, Scheper W (2009) The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus. Am J Pathol 174, 1241-1251.
-
(2009)
Am J Pathol
, vol.174
, pp. 1241-1251
-
-
Hoozemans, J.J.1
Van Haastert, E.S.2
Nijholt, D.A.3
Rozemuller, A.J.4
Eikelenboom, P.5
Scheper, W.6
-
57
-
-
70349305529
-
PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease
-
Morel M, Couturier J, Lafay-Chebassier C, Paccalin M, Page G (2009) PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease. J Cell Mol Med 13, 1476-1488.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 1476-1488
-
-
Morel, M.1
Couturier, J.2
Lafay-Chebassier, C.3
Paccalin, M.4
Page, G.5
-
59
-
-
34248392684
-
Microglial activation and its implications in the brain diseases
-
DOI 10.2174/092986707780597961
-
Dheen ST, Kaur C, Ling EA (2007) Microglial activation and its implications in the brain diseases. Curr Med Chem 14, 1189-1197. (Pubitemid 46739320)
-
(2007)
Current Medicinal Chemistry
, vol.14
, Issue.11
, pp. 1189-1197
-
-
Dheen, S.T.1
Kaur, C.2
Ling, E.-A.3
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