-
1
-
-
0025093189
-
Ethanol inhibits liver regeneration in rats without reducing transcripts of key protooncogenes
-
Diehl, A.M.; Thorgeirsson, S.S.; Steer, C.J. Ethanol inhibits liver regeneration in rats without reducing transcripts of key protooncogenes. Gastroenterology 1990, 99, 1105-1112.
-
(1990)
Gastroenterology
, vol.99
, pp. 1105-1112
-
-
Diehl, A.M.1
Thorgeirsson, S.S.2
Steer, C.J.3
-
2
-
-
0020048371
-
Inhibition of liver regeneration by chronic alcohol administration
-
Duguay, L.; Coutu, D.; Hetu, C.; Joly, J.G. Inhibition of liver regeneration by chronic alcohol administration. Gut 1982, 23, 8-13.
-
(1982)
Gut
, vol.23
, pp. 8-13
-
-
Duguay, L.1
Coutu, D.2
Hetu, C.3
Joly, J.G.4
-
3
-
-
0018398044
-
Inhibition of hepatic regeneration in rats by acute and chronic ethanol intoxication
-
Wands, J.R.; Carter, E.A.; Bucher, N.L.; Isselbacher, K.J. Inhibition of hepatic regeneration in rats by acute and chronic ethanol intoxication. Gastroenterology 1979, 77, 528-531.
-
(1979)
Gastroenterology
, vol.77
, pp. 528-531
-
-
Wands, J.R.1
Carter, E.A.2
Bucher, N.L.3
Isselbacher, K.J.4
-
4
-
-
0018847678
-
Effect of acute and chronic ethanol intoxication on hepatic regeneration
-
Wands, J.R.; Carter, E.A.; Bucher, N.L.; Isselbacher, K.J. Effect of acute and chronic ethanol intoxication on hepatic regeneration. Adv. Exp. Med. Biol. 1980, 132, 663-670.
-
(1980)
Adv. Exp. Med. Biol
, vol.132
, pp. 663-670
-
-
Wands, J.R.1
Carter, E.A.2
Bucher, N.L.3
Isselbacher, K.J.4
-
5
-
-
0032407769
-
Ethanol inhibition of insulin signaling in hepatocellular carcinoma cells
-
Banerjee, K.; Mohr, L.; Wands, J.R.; de la Monte, S.M. Ethanol inhibition of insulin signaling in hepatocellular carcinoma cells. Alcohol Clin. Exp. Res. 1998, 22, 2093-2101.
-
(1998)
Alcohol Clin. Exp. Res
, vol.22
, pp. 2093-2101
-
-
Banerjee, K.1
Mohr, L.2
Wands, J.R.3
de la Monte, S.M.4
-
6
-
-
0021864881
-
Ethanol inhibits hormone stimulated hepatocyte DNA synthesis
-
Carter, E.A.; Wands, J.R. Ethanol inhibits hormone stimulated hepatocyte DNA synthesis. Biochem. Biophys. Res. Commun. 1985, 128, 767-774.
-
(1985)
Biochem. Biophys. Res. Commun
, vol.128
, pp. 767-774
-
-
Carter, E.A.1
Wands, J.R.2
-
7
-
-
0029077617
-
Phosphatidylcholine hydrolysis and DNA synthesis in cultured retinal capillary pericytes
-
Li, W.; Liu, X.; Yanoff, M. Phosphatidylcholine hydrolysis and DNA synthesis in cultured retinal capillary pericytes. Microvasc. Res. 1995, 49, 350-363.
-
(1995)
Microvasc. Res
, vol.49
, pp. 350-363
-
-
Li, W.1
Liu, X.2
Yanoff, M.3
-
8
-
-
0031762799
-
Ethanol inhibits hepatocyte proliferation in insulin receptor substrate 1 transgenic mice
-
Mohr, L.; Tanaka, S.; Wands, J.R. Ethanol inhibits hepatocyte proliferation in insulin receptor substrate 1 transgenic mice. Gastroenterology 1998, 115, 1558-1565.
-
(1998)
Gastroenterology
, vol.115
, pp. 1558-1565
-
-
Mohr, L.1
Tanaka, S.2
Wands, J.R.3
-
9
-
-
0028672544
-
Influence of ethanol on insulin receptor substrate-1-mediated signal transduction during rat liver regeneration
-
Sasaki, Y.; Hayashi, N.; Ito, T.; Fusamoto, H.; Kamada, T.; Wands, J.R. Influence of ethanol on insulin receptor substrate-1-mediated signal transduction during rat liver regeneration. Alcohol Alcoholism 1994, 1, 99-106.
-
(1994)
Alcohol Alcoholism
, vol.1
, pp. 99-106
-
-
Sasaki, Y.1
Hayashi, N.2
Ito, T.3
Fusamoto, H.4
Kamada, T.5
Wands, J.R.6
-
10
-
-
0028004937
-
Ethanol impairs insulin receptor substrate-1 mediated signal transduction during rat liver regeneration
-
Sasaki, Y.; Wands, J.R. Ethanol impairs insulin receptor substrate-1 mediated signal transduction during rat liver regeneration. Biochem. Biophys. Res. Commun. 1994, 199, 403-409.
-
(1994)
Biochem. Biophys. Res. Commun
, vol.199
, pp. 403-409
-
-
Sasaki, Y.1
Wands, J.R.2
-
11
-
-
48549100951
-
Insulin resistance in experimental alcohol-induced liver disease
-
de la Monte, S.M.; Yeon, J.E.; Tong, M.; Longato, L.; Chaudhry, R.; Pang, M.Y.; Duan, K.; Wands, J.R. Insulin resistance in experimental alcohol-induced liver disease. J. Gastroenterol. Hepatol. 2008, 23, e477-86.
-
(2008)
J. Gastroenterol. Hepatol
, vol.23
-
-
de la Monte, S.M.1
Yeon, J.E.2
Tong, M.3
Longato, L.4
Chaudhry, R.5
Pang, M.Y.6
Duan, K.7
Wands, J.R.8
-
12
-
-
67349255861
-
PPARdelta agonist attenuates alcohol-induced hepatic insulin resistance and improves liver injury and repair
-
Pang, M.; de la Monte, S.M.; Longato, L.; Tong, M.; He, J.; Chaudhry, R.; Duan, K.; Ouh, J.; Wands, J.R. PPARdelta agonist attenuates alcohol-induced hepatic insulin resistance and improves liver injury and repair. J. Hepatol. 2009, 50, 1192-1201.
-
(2009)
J. Hepatol
, vol.50
, pp. 1192-1201
-
-
Pang, M.1
de la Monte, S.M.2
Longato, L.3
Tong, M.4
He, J.5
Chaudhry, R.6
Duan, K.7
Ouh, J.8
Wands, J.R.9
-
13
-
-
0031881598
-
The neuropathology of alcohol-specific brain damage, or does alcohol damage the brain?
-
Harper, C. The neuropathology of alcohol-specific brain damage, or does alcohol damage the brain? J. Neuropathol. Exp. Neurol. 1998, 57, 101-110.
-
(1998)
J. Neuropathol. Exp. Neurol
, vol.57
, pp. 101-110
-
-
Harper, C.1
-
14
-
-
0141681163
-
Neuropathological alterations in alcoholic brains. Studies arising from the New South Wales Tissue Resource Centre
-
Harper, C.; Dixon, G.; Sheedy, D.; Garrick, T. Neuropathological alterations in alcoholic brains. Studies arising from the New South Wales Tissue Resource Centre. Prog. Neuropsychopharmacol. Biol. Psychiat. 2003, 27, 951-961.
-
(2003)
Prog. Neuropsychopharmacol. Biol. Psychiat
, vol.27
, pp. 951-961
-
-
Harper, C.1
Dixon, G.2
Sheedy, D.3
Garrick, T.4
-
15
-
-
0023809286
-
Disproportionate atrophy of cerebral white matter in chronic alcoholics
-
de la Monte, S.M. Disproportionate atrophy of cerebral white matter in chronic alcoholics. Arch. Neurol. 1988, 45, 990-992.
-
(1988)
Arch. Neurol
, vol.45
, pp. 990-992
-
-
de la Monte, S.M.1
-
16
-
-
34548249096
-
Insulin and insulin-like growth factor resistance with neurodegeneration in an adult chronic ethanol exposure model
-
Cohen, A.C.; Tong, M.; Wands, J.R.; de la Monte, S.M. Insulin and insulin-like growth factor resistance with neurodegeneration in an adult chronic ethanol exposure model. Alcohol Clin. Exp. Res. 2007, 31, 1558-1573.
-
(2007)
Alcohol Clin. Exp. Res
, vol.31
, pp. 1558-1573
-
-
Cohen, A.C.1
Tong, M.2
Wands, J.R.3
de la Monte, S.M.4
-
17
-
-
15244350991
-
Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: Relevance to Alzheimer's disease
-
de la Monte, S.M.; Wands, J.R. Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease. J. Alzheimers Dis. 2005, 7, 45-61.
-
(2005)
J. Alzheimers Dis
, vol.7
, pp. 45-61
-
-
de la Monte, S.M.1
Wands, J.R.2
-
18
-
-
29244462334
-
Insulin signaling and the regulation of glucose transport
-
Chang, L.; Chiang, S.H.; Saltiel, A.R. Insulin signaling and the regulation of glucose transport. Mol. Med. 2004, 10, 65-71.
-
(2004)
Mol. Med
, vol.10
, pp. 65-71
-
-
Chang, L.1
Chiang, S.H.2
Saltiel, A.R.3
-
19
-
-
0034513781
-
Insulin receptor substrate (IRS) transduction system: Distinct and overlapping signaling potential
-
Giovannone, B.; Scaldaferri, M.L.; Federici, M.; Porzio, O.; Lauro, D.; Fusco, A.; Sbraccia, P.; Borboni, P.; Lauro, R.; Sesti, G. Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential. Diabetes Metab. Res. Rev. 2000, 16, 434-441.
-
(2000)
Diabetes Metab. Res. Rev
, vol.16
, pp. 434-441
-
-
Giovannone, B.1
Scaldaferri, M.L.2
Federici, M.3
Porzio, O.4
Lauro, D.5
Fusco, A.6
Sbraccia, P.7
Borboni, P.8
Lauro, R.9
Sesti, G.10
-
20
-
-
0022384870
-
Insulin receptors in the mammalian central nervous system: Binding characteristics and subunit structure
-
Gammeltoft, S.; Fehlmann, M.; Van, O.E. Insulin receptors in the mammalian central nervous system: binding characteristics and subunit structure. Biochimie 1985, 67, 1147-1153.
-
(1985)
Biochimie
, vol.67
, pp. 1147-1153
-
-
Gammeltoft, S.1
Fehlmann, M.2
Van, O.E.3
-
21
-
-
0022510796
-
Autoradiographic localization of insulin receptors in rat brain: Prominence in olfactory and limbic areas
-
Hill, J.M.; Lesniak, M.A.; Pert, C.B.; Roth, J. Autoradiographic localization of insulin receptors in rat brain: prominence in olfactory and limbic areas. Neuroscience 1986, 17, 1127-1138.
-
(1986)
Neuroscience
, vol.17
, pp. 1127-1138
-
-
Hill, J.M.1
Lesniak, M.A.2
Pert, C.B.3
Roth, J.4
-
22
-
-
33846234628
-
Large-scale generation of highly enriched neural stem-cell-derived oligodendroglial cultures: Maturation-dependent differences in insulin-like growth factor-mediated signal transduction
-
Broughton, S.K.; Chen, H.; Riddle, A.; Kuhn, S.E.; Nagalla, S.; Roberts, C.T., Jr.; Back, S.A. Large-scale generation of highly enriched neural stem-cell-derived oligodendroglial cultures: maturation-dependent differences in insulin-like growth factor-mediated signal transduction. J. Neurochem. 2007, 100, 628-638.
-
(2007)
J. Neurochem
, vol.100
, pp. 628-638
-
-
Broughton, S.K.1
Chen, H.2
Riddle, A.3
Kuhn, S.E.4
Nagalla, S.5
Roberts Jr., C.T.6
Back, S.A.7
-
23
-
-
54349085910
-
IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination
-
Freude, S.; Leeser, U.; Muller, M.; Hettich, M.M.; Udelhoven, M.; Schilbach, K.; Tobe, K.; Kadowaki, T.; Kohler, C.; Schroder, H.; Krone, W.; Bruning, J.C.; Schubert, M. IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination. J. Neurochem. 2008, 107, 907-917.
-
(2008)
J. Neurochem
, vol.107
, pp. 907-917
-
-
Freude, S.1
Leeser, U.2
Muller, M.3
Hettich, M.M.4
Udelhoven, M.5
Schilbach, K.6
Tobe, K.7
Kadowaki, T.8
Kohler, C.9
Schroder, H.10
Krone, W.11
Bruning, J.C.12
Schubert, M.13
-
24
-
-
57349130542
-
Expanding the mind: Insulin-like growth factor I and brain development
-
Joseph D'Ercole, A.; Ye, P. Expanding the mind: insulin-like growth factor I and brain development. Endocrinology 2008, 149, 5958-5962.
-
(2008)
Endocrinology
, vol.149
, pp. 5958-5962
-
-
Joseph D'Ercole, A.1
Ye, P.2
-
25
-
-
0043127453
-
Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation
-
Schubert, M.; Brazil, D.P.; Burks, D.J.; Kushner, J.A.; Ye, J.; Flint, C.L.; Farhang-Fallah, J.; Dikkes, P.; Warot, X.M.; Rio, C.; Corfas, G.; White, M.F. Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation. J. Neurosci. 2003, 23, 7084-7092.
-
(2003)
J. Neurosci
, vol.23
, pp. 7084-7092
-
-
Schubert, M.1
Brazil, D.P.2
Burks, D.J.3
Kushner, J.A.4
Ye, J.5
Flint, C.L.6
Farhang-Fallah, J.7
Dikkes, P.8
Warot, X.M.9
Rio, C.10
Corfas, G.11
White, M.F.12
-
26
-
-
45949088803
-
Insulin-like growth factor system regulates oligodendroglial cell behavior: Therapeutic potential in CNS
-
Chesik, D.; de Keyser, J.; Wilczak, N. Insulin-like growth factor system regulates oligodendroglial cell behavior: therapeutic potential in CNS. J. Mol. Neurosci. 2008, 35, 81-90.
-
(2008)
J. Mol. Neurosci
, vol.35
, pp. 81-90
-
-
Chesik, D.1
de Keyser, J.2
Wilczak, N.3
-
27
-
-
47549085152
-
Invivo insulin deficiency as a potential etiology for demyelinating disease
-
Gong, X.; Xie, Z.; Zuo, H. Invivo insulin deficiency as a potential etiology for demyelinating disease. Med. Hypotheses 2008, 71, 399-403.
-
(2008)
Med. Hypotheses
, vol.71
, pp. 399-403
-
-
Gong, X.1
Xie, Z.2
Zuo, H.3
-
28
-
-
33947544451
-
IGF-1 stimulates de novo fatty acid biosynthesis by Schwann cells during myelination
-
Liang, G.; Cline, G.W.; Macica, C.M. IGF-1 stimulates de novo fatty acid biosynthesis by Schwann cells during myelination. Glia 2007, 55, 632-641.
-
(2007)
Glia
, vol.55
, pp. 632-641
-
-
Liang, G.1
Cline, G.W.2
Macica, C.M.3
-
29
-
-
33947232272
-
Insulin-like growth factor-I ameliorates demyelination induced by tumor necrosis factor-alpha in transgenic mice
-
Ye, P.; Kollias, G.; D'Ercole, A.J. Insulin-like growth factor-I ameliorates demyelination induced by tumor necrosis factor-alpha in transgenic mice. J. Neurosci. Res. 2007, 85, 712-722.
-
(2007)
J. Neurosci. Res
, vol.85
, pp. 712-722
-
-
Ye, P.1
Kollias, G.2
D'Ercole, A.J.3
-
30
-
-
0009513068
-
Ethanol and IRS-1 protein in the liver and brain
-
Lund, Sweden
-
Wands, J.R.; Mohr, L.; Banerjee, K.; Ganju, N.; Tanaka, S.; de la Monte, S.M. Ethanol and IRS-1 protein in the liver and brain. In Proceedings on Signal Transduction and Alcohol, Lund, Sweden, 2001.
-
(2001)
Proceedings on Signal Transduction and Alcohol
-
-
Wands, J.R.1
Mohr, L.2
Banerjee, K.3
Ganju, N.4
Tanaka, S.5
de la Monte, S.M.6
-
31
-
-
0041822087
-
Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver
-
Yeon, J.E.; Califano, S.; Xu, J.; Wands, J.R.; De La Monte, S.M. Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver. Hepatology 2003, 38, 703-714.
-
(2003)
Hepatology
, vol.38
, pp. 703-714
-
-
Yeon, J.E.1
Califano, S.2
Xu, J.3
Wands, J.R.4
De La Monte, S.M.5
-
32
-
-
40149085591
-
Cytokine and chemokine expression associated with steatohepatitis and hepatocyte proliferation in rats fed ethanol via total enteral nutrition
-
Ronis, M.J.; Butura, A.; Korourian, S.; Shankar, K.; Simpson, P.; Badeaux, J.; Albano, E.; Ingelman-Sundberg, M.; Badger, T.M. Cytokine and chemokine expression associated with steatohepatitis and hepatocyte proliferation in rats fed ethanol via total enteral nutrition. Exp. Biol. Med. (Maywood) 2008, 233, 344-355.
-
(2008)
Exp. Biol. Med. (Maywood)
, vol.233
, pp. 344-355
-
-
Ronis, M.J.1
Butura, A.2
Korourian, S.3
Shankar, K.4
Simpson, P.5
Badeaux, J.6
Albano, E.7
Ingelman-Sundberg, M.8
Badger, T.M.9
-
33
-
-
0036282840
-
Chronic gestational exposure to ethanol impairs insulin-stimulated survival and mitochondrial function in cerebellar neurons
-
de la Monte, S.M.; Wands, J.R. Chronic gestational exposure to ethanol impairs insulin-stimulated survival and mitochondrial function in cerebellar neurons. CMLS, Cell Mol. Life Sci. 2002, 59, 882-893.
-
(2002)
CMLS, Cell Mol. Life Sci
, vol.59
, pp. 882-893
-
-
de la Monte, S.M.1
Wands, J.R.2
-
34
-
-
20944441349
-
Ethanol inhibits insulin expression and actions in the developing brain
-
de la Monte, S.M.; Xu, X.J.; Wands, J.R. Ethanol inhibits insulin expression and actions in the developing brain. Cell Mol. Life Sci. 2005, 62, 1131-1145.
-
(2005)
Cell Mol. Life Sci
, vol.62
, pp. 1131-1145
-
-
de la Monte, S.M.1
Xu, X.J.2
Wands, J.R.3
-
35
-
-
50849117830
-
Insulin and insulin-like growth factor resistance in alcoholic neurodegeneration
-
de la Monte, S.M.; Tong, M.; Cohen, A.C.; Sheedy, D.; Harper, C.; Wands, J.R. Insulin and insulin-like growth factor resistance in alcoholic neurodegeneration. Alcohol Clin. Exp. Res. 2008, 32, 1630-1644.
-
(2008)
Alcohol Clin. Exp. Res
, vol.32
, pp. 1630-1644
-
-
de la Monte, S.M.1
Tong, M.2
Cohen, A.C.3
Sheedy, D.4
Harper, C.5
Wands, J.R.6
-
36
-
-
33748478598
-
Chronic gestational exposure to ethanol causes insulin and IGF resistance and impairs acetylcholine homeostasis in the brain
-
Soscia, S.J.; Tong, M.; Xu, X.J.; Cohen, A.C.; Chu, J.; Wands, J.R.; de la Monte, S.M. Chronic gestational exposure to ethanol causes insulin and IGF resistance and impairs acetylcholine homeostasis in the brain. Cell Mol. Life Sci. 2006, 63, 2039-2056.
-
(2006)
Cell Mol. Life Sci
, vol.63
, pp. 2039-2056
-
-
Soscia, S.J.1
Tong, M.2
Xu, X.J.3
Cohen, A.C.4
Chu, J.5
Wands, J.R.6
de la Monte, S.M.7
-
37
-
-
34447330765
-
Alcohol-induced disruption of endocrine signaling
-
Ronis, M.J.; Wands, J.R.; Badger, T.M.; de la Monte, S.M.; Lang, C.H.; Calissendorff, J. Alcohol-induced disruption of endocrine signaling. Alcohol Clin. Exp. Res. 2007, 31, 1269-1285.
-
(2007)
Alcohol Clin. Exp. Res
, vol.31
, pp. 1269-1285
-
-
Ronis, M.J.1
Wands, J.R.2
Badger, T.M.3
de la Monte, S.M.4
Lang, C.H.5
Calissendorff, J.6
-
38
-
-
0041430945
-
Prevention of ethanol-induced liver injury in rats by an agonist of peroxisome proliferator-activated receptor-gamma, pioglitazone
-
Enomoto, N.; Takei, Y.; Hirose, M.; Konno, A.; Shibuya, T.; Matsuyama, S.; Suzuki, S.; Kitamura, K.I.; Sato, N. Prevention of ethanol-induced liver injury in rats by an agonist of peroxisome proliferator-activated receptor-gamma, pioglitazone. J. Pharmacol. Exp. Ther. 2003, 306, 846-854.
-
(2003)
J. Pharmacol. Exp. Ther
, vol.306
, pp. 846-854
-
-
Enomoto, N.1
Takei, Y.2
Hirose, M.3
Konno, A.4
Shibuya, T.5
Matsuyama, S.6
Suzuki, S.7
Kitamura, K.I.8
Sato, N.9
-
39
-
-
0344211825
-
Ethanol feeding induces insulin resistance with enhanced PI 3-kinase activation
-
Onishi, Y.; Honda, M.; Ogihara, T.; Sakoda, H.; Anai, M.; Fujishiro, M.; Ono, H.; Shojima, N.; Fukushima, Y.; Inukai, K.; Katagiri, H.; Kikuchi, M.; Oka, Y.; Asano, T. Ethanol feeding induces insulin resistance with enhanced PI 3-kinase activation. Biochem. Biophys. Res. Commun. 2003, 303, 788-794.
-
(2003)
Biochem. Biophys. Res. Commun
, vol.303
, pp. 788-794
-
-
Onishi, Y.1
Honda, M.2
Ogihara, T.3
Sakoda, H.4
Anai, M.5
Fujishiro, M.6
Ono, H.7
Shojima, N.8
Fukushima, Y.9
Inukai, K.10
Katagiri, H.11
Kikuchi, M.12
Oka, Y.13
Asano, T.14
-
40
-
-
0025940396
-
Impairment of hepatic insulin receptors during chronic ethanol administration
-
Patel, B.C.; D'Arville, C.; Iwahashi, M.; Simon, F.R. Impairment of hepatic insulin receptors during chronic ethanol administration. Am. J. Physiol. 1991, 261, G199-205.
-
(1991)
Am. J. Physiol
, vol.261
-
-
Patel, B.C.1
D'Arville, C.2
Iwahashi, M.3
Simon, F.R.4
-
41
-
-
21844448117
-
Increased incidence of hepatic insulin-sensitizing substance (HISS)-dependent insulin resistance in female rats prenatally exposed to ethanol
-
Sadri, P.; Legare, D.J.; Takayama, S.; Lautt, W.W. Increased incidence of hepatic insulin-sensitizing substance (HISS)-dependent insulin resistance in female rats prenatally exposed to ethanol. Can. J. Physiol. Pharmacol. 2005, 83, 383-387.
-
(2005)
Can. J. Physiol. Pharmacol
, vol.83
, pp. 383-387
-
-
Sadri, P.1
Legare, D.J.2
Takayama, S.3
Lautt, W.W.4
-
42
-
-
10744221756
-
Pioglitazone prevents alcohol-induced fatty liver in rats through up-regulation of c-Met
-
Tomita, K.; Azuma, T.; Kitamura, N.; Nishida, J.; Tamiya, G.; Oka, A.; Inokuchi, S.; Nishimura, T.; Suematsu, M.; Ishii, H. Pioglitazone prevents alcohol-induced fatty liver in rats through up-regulation of c-Met. Gastroenterology 2004, 126, 873-885.
-
(2004)
Gastroenterology
, vol.126
, pp. 873-885
-
-
Tomita, K.1
Azuma, T.2
Kitamura, N.3
Nishida, J.4
Tamiya, G.5
Oka, A.6
Inokuchi, S.7
Nishimura, T.8
Suematsu, M.9
Ishii, H.10
-
43
-
-
33646351086
-
Adult rats prenatally exposed to ethanol have increased gluconeogenesis and impaired insulin response of hepatic gluconeogenic genes
-
Yao, X.H.; Chen, L.; Nyomba, B.L. Adult rats prenatally exposed to ethanol have increased gluconeogenesis and impaired insulin response of hepatic gluconeogenic genes. J. Appl. Physiol. 2006, 100, 642-648.
-
(2006)
J. Appl. Physiol
, vol.100
, pp. 642-648
-
-
Yao, X.H.1
Chen, L.2
Nyomba, B.L.3
-
44
-
-
20544447208
-
The influence of phosphatidylinositol 3-kinase/Akt pathway on the ischemic injury during rat liver graft preservation
-
Li, X.L.; Man, K.; Ng, K.T.; Sun, C.K.; Lo, C.M.; Fan, S.T. The influence of phosphatidylinositol 3-kinase/Akt pathway on the ischemic injury during rat liver graft preservation. Am. J. Transplant. 2005, 5, 1264-1275.
-
(2005)
Am. J. Transplant
, vol.5
, pp. 1264-1275
-
-
Li, X.L.1
Man, K.2
Ng, K.T.3
Sun, C.K.4
Lo, C.M.5
Fan, S.T.6
-
45
-
-
27744459507
-
Mechanisms of disease: PI3K/AKT signaling in gastrointestinal cancers
-
Michl, P.; Downward, J. Mechanisms of disease: PI3K/AKT signaling in gastrointestinal cancers. Z. Gastroenterol. 2005, 43, 1133-1139.
-
(2005)
Z. Gastroenterol
, vol.43
, pp. 1133-1139
-
-
Michl, P.1
Downward, J.2
-
46
-
-
0033950358
-
The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis
-
Roberts, R.A.; James, N.H.; Cosulich, S.C. The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis. Hepatology 2000, 31, 420-427.
-
(2000)
Hepatology
, vol.31
, pp. 420-427
-
-
Roberts, R.A.1
James, N.H.2
Cosulich, S.C.3
-
47
-
-
21744449745
-
Phosphatidylinositol 3-kinase-dependent signaling modulates taurochenodeoxycholic acid-induced liver injury and cholestasis in perfused rat livers
-
Rust, C.; Bauchmuller, K.; Fickert, P.; Fuchsbichler, A.; Beuers, U. Phosphatidylinositol 3-kinase-dependent signaling modulates taurochenodeoxycholic acid-induced liver injury and cholestasis in perfused rat livers. Am. J. Physiol. Gastrointest. Liver Physiol. 2005, 289, G88-94.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.289
-
-
Rust, C.1
Bauchmuller, K.2
Fickert, P.3
Fuchsbichler, A.4
Beuers, U.5
-
48
-
-
10644268512
-
IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes
-
Valverde, A.M.; Fabregat, I.; Burks, D.J.; White, M.F.; Benito, M. IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes. Hepatology 2004, 40, 1285-1294.
-
(2004)
Hepatology
, vol.40
, pp. 1285-1294
-
-
Valverde, A.M.1
Fabregat, I.2
Burks, D.J.3
White, M.F.4
Benito, M.5
-
49
-
-
0345059393
-
Binge ethanol exposure increases liver injury in obese rats
-
Carmiel-Haggai, M.; Cederbaum, A.I.; Nieto, N. Binge ethanol exposure increases liver injury in obese rats. Gastroenterology 2003, 125, 1818-1833.
-
(2003)
Gastroenterology
, vol.125
, pp. 1818-1833
-
-
Carmiel-Haggai, M.1
Cederbaum, A.I.2
Nieto, N.3
-
50
-
-
33750283354
-
Ethanol-induced apoptosis in polarized hepatic cells possibly through regulation of the Fas pathway
-
McVicker, B.L.; Tuma, D.J.; Kubik, J.L.; Tuma, P.L.; Casey, C.A. Ethanol-induced apoptosis in polarized hepatic cells possibly through regulation of the Fas pathway. Alcohol Clin. Exp. Res. 2006, 30, 1906-1915.
-
(2006)
Alcohol Clin. Exp. Res
, vol.30
, pp. 1906-1915
-
-
McVicker, B.L.1
Tuma, D.J.2
Kubik, J.L.3
Tuma, P.L.4
Casey, C.A.5
-
51
-
-
0034128363
-
Partial rescue of ethanol-induced neuronal apoptosis by growth factor activation of phosphoinositol-3-kinase
-
de la Monte, S.M.; Ganju, N.; Banerjee, K.; Brown, N.V.; Luong, T.; Wands, J.R. Partial rescue of ethanol-induced neuronal apoptosis by growth factor activation of phosphoinositol-3-kinase. Alcohol Clin. Exp. Res. 2000, 24, 716-726.
-
(2000)
Alcohol Clin. Exp. Res
, vol.24
, pp. 716-726
-
-
de la Monte, S.M.1
Ganju, N.2
Banerjee, K.3
Brown, N.V.4
Luong, T.5
Wands, J.R.6
-
52
-
-
0035197347
-
Ethanol impairs insulin-stimulated mitochondrial function in cerebellar granule neurons
-
de la Monte, S.M.; Neely, T.R.; Cannon, J.; Wands, J.R. Ethanol impairs insulin-stimulated mitochondrial function in cerebellar granule neurons. Cell Mol. Life Sci. 2001, 58, 1950-1960.
-
(2001)
Cell Mol. Life Sci
, vol.58
, pp. 1950-1960
-
-
de la Monte, S.M.1
Neely, T.R.2
Cannon, J.3
Wands, J.R.4
-
53
-
-
0034947425
-
Inhibition of insulin-like growth factor-I signaling by ethanol in neuronal cells
-
Hallak, H.; Seiler, A.E.; Green, J.S.; Henderson, A.; Ross, B.N.; Rubin, R. Inhibition of insulin-like growth factor-I signaling by ethanol in neuronal cells. Alcohol Clin. Exp. Res. 2001, 25, 1058-1064.
-
(2001)
Alcohol Clin. Exp. Res
, vol.25
, pp. 1058-1064
-
-
Hallak, H.1
Seiler, A.E.2
Green, J.S.3
Henderson, A.4
Ross, B.N.5
Rubin, R.6
-
54
-
-
0031812482
-
Ethanol induces apoptosis in cerebellar granule neurons by inhibiting insulin-like growth factor 1 signaling
-
Zhang, F.X.; Rubin, R.; Rooney, T.A. Ethanol induces apoptosis in cerebellar granule neurons by inhibiting insulin-like growth factor 1 signaling. J. Neurochem. 1998, 71, 196-204.
-
(1998)
J. Neurochem
, vol.71
, pp. 196-204
-
-
Zhang, F.X.1
Rubin, R.2
Rooney, T.A.3
-
55
-
-
68249128077
-
Acetaldehyde-Mediated neuronal apoptosis and mitochondrial dysfunction: Relevance to fetal alcohol syndrome
-
Submitted
-
Spaissman, A.; Tong, M.; de la Monte, S.M. Acetaldehyde-Mediated neuronal apoptosis and mitochondrial dysfunction: relevance to fetal alcohol syndrome. J. Neurochem. 2009, (Submitted).
-
(2009)
J. Neurochem
-
-
Spaissman, A.1
Tong, M.2
de la Monte, S.M.3
-
56
-
-
0034972410
-
In utero ethanol exposure causes mitochondrial dysfunction, which can result in apoptotic cell death in fetal brain: A potential role for 4-hydroxynonenal
-
Ramachandran, V.; Perez, A.; Chen, J.; Senthil, D.; Schenker, S.; Henderson, G.I. In utero ethanol exposure causes mitochondrial dysfunction, which can result in apoptotic cell death in fetal brain: a potential role for 4-hydroxynonenal. Alcohol Clin. Exp. Res. 2001, 25, 862-871.
-
(2001)
Alcohol Clin. Exp. Res
, vol.25
, pp. 862-871
-
-
Ramachandran, V.1
Perez, A.2
Chen, J.3
Senthil, D.4
Schenker, S.5
Henderson, G.I.6
-
57
-
-
0034635370
-
Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome
-
Ikonomidou, C.; Bittigau, P.; Ishimaru, M.J.; Wozniak, D.F.; Koch, C.; Genz, K.; Price, M.T.; Stefovska, V.; Horster, F.; Tenkova, T.; Dikranian, K.; Olney, J.W. Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome. Science 2000, 287, 1056-1060.
-
(2000)
Science
, vol.287
, pp. 1056-1060
-
-
Ikonomidou, C.1
Bittigau, P.2
Ishimaru, M.J.3
Wozniak, D.F.4
Koch, C.5
Genz, K.6
Price, M.T.7
Stefovska, V.8
Horster, F.9
Tenkova, T.10
Dikranian, K.11
Olney, J.W.12
-
58
-
-
0034971103
-
Mitochondrial DNA damage and impaired mitochondrial function contribute to apoptosis of insulin-stimulated ethanol-exposed neuronal cells
-
de la Monte, S.M.; Wands, J.R. Mitochondrial DNA damage and impaired mitochondrial function contribute to apoptosis of insulin-stimulated ethanol-exposed neuronal cells. Alcohol Clin. Exp. Res. 2001, 25, 898-906.
-
(2001)
Alcohol Clin. Exp. Res
, vol.25
, pp. 898-906
-
-
de la Monte, S.M.1
Wands, J.R.2
-
59
-
-
0038711749
-
Ethanol impairs insulin-stimulated neuronal survival in the developing brain: Role of PTEN phosphatase
-
Xu, J.; Yeon, J.E.; Chang, H.; Tison, G.; Chen, G.J.; Wands, J.; de la Monte, S. Ethanol impairs insulin-stimulated neuronal survival in the developing brain: role of PTEN phosphatase. J. Biol. Chem. 2003, 278, 26929-26937.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 26929-26937
-
-
Xu, J.1
Yeon, J.E.2
Chang, H.3
Tison, G.4
Chen, G.J.5
Wands, J.6
de la Monte, S.7
-
60
-
-
0022631862
-
Alterations induced by chronic ethanol treatment on lipid composition of microsomes, mitochondria and myelin from neonatal chick liver and brain
-
Marco, C.; Ceacero, F.; Gonzalez-Pacanowska, D.; Garcia-Peregrin, E.; Segovia, J.L. Alterations induced by chronic ethanol treatment on lipid composition of microsomes, mitochondria and myelin from neonatal chick liver and brain. Biochem. Int. 1986, 12, 51-60.
-
(1986)
Biochem. Int
, vol.12
, pp. 51-60
-
-
Marco, C.1
Ceacero, F.2
Gonzalez-Pacanowska, D.3
Garcia-Peregrin, E.4
Segovia, J.L.5
-
61
-
-
0036934974
-
Interaction of phosphatidylinositolglycan(-peptides) with plasma membrane lipid rafts triggers insulin-mimetic signaling in rat adipocytes
-
Muller, G.; Jung, C.; Frick, W.; Bandlow, W.; Kramer, W. Interaction of phosphatidylinositolglycan(-peptides) with plasma membrane lipid rafts triggers insulin-mimetic signaling in rat adipocytes. Arch. Biochem. Biophys. 2002, 408, 7-16.
-
(2002)
Arch. Biochem. Biophys
, vol.408
, pp. 7-16
-
-
Muller, G.1
Jung, C.2
Frick, W.3
Bandlow, W.4
Kramer, W.5
-
62
-
-
33746340885
-
Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: Relationship to histological improvement
-
Lutchman, G.; Promrat, K.; Kleiner, D.E.; Heller, T.; Ghany, M.G.; Yanovski, J.A.; Liang, T.J.; Hoofnagle, J.H. Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: relationship to histological improvement. Clin. Gastroenterol. Hepatol. 2006, 4, 1048-1052.
-
(2006)
Clin. Gastroenterol. Hepatol
, vol.4
, pp. 1048-1052
-
-
Lutchman, G.1
Promrat, K.2
Kleiner, D.E.3
Heller, T.4
Ghany, M.G.5
Yanovski, J.A.6
Liang, T.J.7
Hoofnagle, J.H.8
-
63
-
-
1442355447
-
A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis
-
Promrat, K.; Lutchman, G.; Uwaifo, G.I.; Freedman, R.J.; Soza, A.; Heller, T.; Doo, E.; Ghany, M.; Premkumar, A.; Park, Y.; Liang, T.J.; Yanovski, J.A.; Kleiner, D.E.; Hoofnagle, J.H. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology 2004, 39, 188-196.
-
(2004)
Hepatology
, vol.39
, pp. 188-196
-
-
Promrat, K.1
Lutchman, G.2
Uwaifo, G.I.3
Freedman, R.J.4
Soza, A.5
Heller, T.6
Doo, E.7
Ghany, M.8
Premkumar, A.9
Park, Y.10
Liang, T.J.11
Yanovski, J.A.12
Kleiner, D.E.13
Hoofnagle, J.H.14
-
64
-
-
62749172933
-
Insulin resistance and steatosis in humans
-
Capeau, J. Insulin resistance and steatosis in humans. Diabetes Metab. 2008, 34, 649-657.
-
(2008)
Diabetes Metab
, vol.34
, pp. 649-657
-
-
Capeau, J.1
-
65
-
-
29744456063
-
Insulin resistance in the Zucker diabetic fatty rat: A metabolic characterisation of obese and lean phenotypes
-
Leonard, B.L.; Watson, R.N.; Loomes, K.M.; Phillips, A.R.; Cooper, G.J. Insulin resistance in the Zucker diabetic fatty rat: a metabolic characterisation of obese and lean phenotypes. Acta Diabetol. 2005, 42, 162-170.
-
(2005)
Acta Diabetol
, vol.42
, pp. 162-170
-
-
Leonard, B.L.1
Watson, R.N.2
Loomes, K.M.3
Phillips, A.R.4
Cooper, G.J.5
-
66
-
-
43249083481
-
Free fatty acids and skeletal muscle insulin resistance
-
Kraegen, E.W.; Cooney, G.J. Free fatty acids and skeletal muscle insulin resistance. Curr. Opin. Lipidol. 2008, 19, 235-241.
-
(2008)
Curr. Opin. Lipidol
, vol.19
, pp. 235-241
-
-
Kraegen, E.W.1
Cooney, G.J.2
-
67
-
-
0033064602
-
Effects of insulin on lipid metabolism of larvae and metamorphosing landlocked sea lamprey, Petromyzon marinus
-
Kao, Y.; Youson, J.H.; Holmes, J.A.; Al-Mahrouki, A.; Sheridan, M.A. Effects of insulin on lipid metabolism of larvae and metamorphosing landlocked sea lamprey, Petromyzon marinus. Gen. Comp. Endocrinol. 1999, 114, 405-414.
-
(1999)
Gen. Comp. Endocrinol
, vol.114
, pp. 405-414
-
-
Kao, Y.1
Youson, J.H.2
Holmes, J.A.3
Al-Mahrouki, A.4
Sheridan, M.A.5
-
68
-
-
45149106053
-
Sphingolipids, insulin resistance, and metabolic disease: New insights from in vivo manipulation of sphingolipid metabolism
-
Holland, W.L.; Summers, S.A. Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism. Endocr. Rev. 2008, 29, 381-402.
-
(2008)
Endocr. Rev
, vol.29
, pp. 381-402
-
-
Holland, W.L.1
Summers, S.A.2
-
69
-
-
67349130083
-
Glycosphingolipids and insulin resistance
-
Langeveld, M.; Aerts, J.M. Glycosphingolipids and insulin resistance. Prog. Lipid. Res. 2009, 48, 196-205.
-
(2009)
Prog. Lipid. Res
, vol.48
, pp. 196-205
-
-
Langeveld, M.1
Aerts, J.M.2
-
70
-
-
31644443192
-
Ceramides in insulin resistance and lipotoxicity
-
Summers, S.A. Ceramides in insulin resistance and lipotoxicity. Prog. Lipid. Res. 2006, 45, 42-72.
-
(2006)
Prog. Lipid. Res
, vol.45
, pp. 42-72
-
-
Summers, S.A.1
-
71
-
-
44749091972
-
Ceramide: A contributor to insulin resistance or an innocent bystander?
-
Boden, G. Ceramide: a contributor to insulin resistance or an innocent bystander? Diabetologia 2008, 51, 1095-1096.
-
(2008)
Diabetologia
, vol.51
, pp. 1095-1096
-
-
Boden, G.1
-
73
-
-
33847332202
-
Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance
-
Holland, W.L.; Brozinick, J.T.; Wang, L.P.; Hawkins, E.D.; Sargent, K.M.; Liu, Y.; Narra, K.; Hoehn, K.L.; Knotts, T.A.; Siesky, A.; Nelson, D.H.; Karathanasis, S.K.; Fontenot, G.K.; Birnbaum, M.J.; Summers, S.A. Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance. Cell Metab. 2007, 5, 167-179.
-
(2007)
Cell Metab
, vol.5
, pp. 167-179
-
-
Holland, W.L.1
Brozinick, J.T.2
Wang, L.P.3
Hawkins, E.D.4
Sargent, K.M.5
Liu, Y.6
Narra, K.7
Hoehn, K.L.8
Knotts, T.A.9
Siesky, A.10
Nelson, D.H.11
Karathanasis, S.K.12
Fontenot, G.K.13
Birnbaum, M.J.14
Summers, S.A.15
-
74
-
-
84860493578
-
Lipid mediators of insulin resistance
-
Holland, W.L.; Knotts, T.A.; Chavez, J.A.; Wang, L.P.; Hoehn, K.L.; Summers, S.A. Lipid mediators of insulin resistance. Nutr. Rev. 2007, 65, S39-46.
-
(2007)
Nutr. Rev
, vol.65
-
-
Holland, W.L.1
Knotts, T.A.2
Chavez, J.A.3
Wang, L.P.4
Hoehn, K.L.5
Summers, S.A.6
-
75
-
-
54049150442
-
Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis
-
Anderson, N.; Borlak, J. Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis. Pharmacol. Rev. 2008, 60, 311-357.
-
(2008)
Pharmacol. Rev
, vol.60
, pp. 311-357
-
-
Anderson, N.1
Borlak, J.2
-
76
-
-
35948950834
-
Endoplasmic reticulum stress and liver injury
-
Kaplowitz, N.; Than, T.A.; Shinohara, M.; Ji, C. Endoplasmic reticulum stress and liver injury. Semin. Liver Dis. 2007, 27, 367-377.
-
(2007)
Semin. Liver Dis
, vol.27
, pp. 367-377
-
-
Kaplowitz, N.1
Than, T.A.2
Shinohara, M.3
Ji, C.4
-
77
-
-
56649094325
-
Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease
-
Malhi, H.; Gores, G.J. Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease. Semin. Liver Dis. 2008, 28, 360-369.
-
(2008)
Semin. Liver Dis
, vol.28
, pp. 360-369
-
-
Malhi, H.1
Gores, G.J.2
-
78
-
-
34249302400
-
Endoplasmic reticulum (ER) stress & diabetes
-
Sundar Rajan, S.; Srinivasan, V.; Balasubramanyam, M.; Tatu, U. Endoplasmic reticulum (ER) stress & diabetes. Indian J. Med. Res. 2007, 125, 411-424.
-
(2007)
Indian J. Med. Res
, vol.125
, pp. 411-424
-
-
Sundar Rajan, S.1
Srinivasan, V.2
Balasubramanyam, M.3
Tatu, U.4
-
79
-
-
0036479251
-
Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: Implications for growth arrest
-
Bourbon, N.A.; Sandirasegarane, L.; Kester, M. Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: implications for growth arrest. J. Biol. Chem. 2002, 277, 3286-3292.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 3286-3292
-
-
Bourbon, N.A.1
Sandirasegarane, L.2
Kester, M.3
-
80
-
-
0035133331
-
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
-
Hajduch, E.; Balendran, A.; Batty, I.H.; Litherland, G.J.; Blair, A.S.; Downes, C.P.; Hundal, H.S. Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. Diabetologia 2001, 44, 173-183.
-
(2001)
Diabetologia
, vol.44
, pp. 173-183
-
-
Hajduch, E.1
Balendran, A.2
Batty, I.H.3
Litherland, G.J.4
Blair, A.S.5
Downes, C.P.6
Hundal, H.S.7
-
81
-
-
58149333763
-
Involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion
-
Nogueira, T.C.; Anhe, G.F.; Carvalho, C.R.; Curi, R.; Bordin, S.; Carpinelli, A.R. Involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion. Pancreas 2008, 37, 309-315.
-
(2008)
Pancreas
, vol.37
, pp. 309-315
-
-
Nogueira, T.C.1
Anhe, G.F.2
Carvalho, C.R.3
Curi, R.4
Bordin, S.5
Carpinelli, A.R.6
-
82
-
-
0142091454
-
Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism
-
Powell, D.J.; Hajduch, E.; Kular, G.; Hundal, H.S. Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism. Mol. Cell Biol. 2003, 23, 7794-7808.
-
(2003)
Mol. Cell Biol
, vol.23
, pp. 7794-7808
-
-
Powell, D.J.1
Hajduch, E.2
Kular, G.3
Hundal, H.S.4
-
83
-
-
61849185113
-
Intramuscular lipid metabolism, insulin action, and obesity
-
Consitt, L.A.; Bell, J.A.; Houmard, J.A. Intramuscular lipid metabolism, insulin action, and obesity. IUBMB Life 2009, 61, 47-55.
-
(2009)
IUBMB Life
, vol.61
, pp. 47-55
-
-
Consitt, L.A.1
Bell, J.A.2
Houmard, J.A.3
-
84
-
-
38949210754
-
Effect of gender on lipid-induced insulin resistance in obese subjects
-
Vistisen, B.; Hellgren, L.I.; Vadset, T.; Scheede-Bergdahl, C.; Helge, J.W.; Dela, F.; Stallknecht, B. Effect of gender on lipid-induced insulin resistance in obese subjects. Eur. J. Endocrinol. 2008, 158, 61-68.
-
(2008)
Eur. J. Endocrinol
, vol.158
, pp. 61-68
-
-
Vistisen, B.1
Hellgren, L.I.2
Vadset, T.3
Scheede-Bergdahl, C.4
Helge, J.W.5
Dela, F.6
Stallknecht, B.7
-
85
-
-
33847308760
-
The path to insulin resistance: Paved with ceramides?
-
Zierath, J.R. The path to insulin resistance: paved with ceramides? Cell Metab. 2007, 5, 161-163.
-
(2007)
Cell Metab
, vol.5
, pp. 161-163
-
-
Zierath, J.R.1
-
86
-
-
58149308844
-
Altered lipid metabolism in brain injury and disorders
-
Adibhatla, R.M.; Hatcher, J.F. Altered lipid metabolism in brain injury and disorders. Subcell Biochem. 2008, 49, 241-268.
-
(2008)
Subcell Biochem
, vol.49
, pp. 241-268
-
-
Adibhatla, R.M.1
Hatcher, J.F.2
-
87
-
-
39549095800
-
Remyelination in experimental models of toxin-induced demyelination
-
Blakemore, W.F.; Franklin, R.J. Remyelination in experimental models of toxin-induced demyelination. Curr. Top Microbiol. Immunol. 2008, 318, 193-212.
-
(2008)
Curr. Top Microbiol. Immunol
, vol.318
, pp. 193-212
-
-
Blakemore, W.F.1
Franklin, R.J.2
-
88
-
-
58149101571
-
Effect of hypoxic-ischemic injury on serine palmitoyltransferase activity in the developing rat brain
-
Daigo, M.; Arai, Y.; Oshida, K.; Kitamura, Y.; Hayashi, M.; Shimizu, T.; Yamashiro, Y. Effect of hypoxic-ischemic injury on serine palmitoyltransferase activity in the developing rat brain. Pathobiology 2008, 75, 330-334.
-
(2008)
Pathobiology
, vol.75
, pp. 330-334
-
-
Daigo, M.1
Arai, Y.2
Oshida, K.3
Kitamura, Y.4
Hayashi, M.5
Shimizu, T.6
Yamashiro, Y.7
-
89
-
-
3042599022
-
Inhibition of sphingomyelinase activity helps to prevent neuron death caused by ischemic stress
-
Soeda, S.; Tsuji, Y.; Ochiai, T.; Mishima, K.; Iwasaki, K.; Fujiwara, M.; Yokomatsu, T.; Murano, T.; Shibuya, S.; Shimeno, H. Inhibition of sphingomyelinase activity helps to prevent neuron death caused by ischemic stress. Neurochem. Int. 2004, 45, 619-626.
-
(2004)
Neurochem. Int
, vol.45
, pp. 619-626
-
-
Soeda, S.1
Tsuji, Y.2
Ochiai, T.3
Mishima, K.4
Iwasaki, K.5
Fujiwara, M.6
Yokomatsu, T.7
Murano, T.8
Shibuya, S.9
Shimeno, H.10
-
90
-
-
27744577642
-
Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1
-
Soriano, J.M.; Gonzalez, L.; Catala, A.I. Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1. Prog. Lipid. Res. 2005, 44, 345-356.
-
(2005)
Prog. Lipid. Res
, vol.44
, pp. 345-356
-
-
Soriano, J.M.1
Gonzalez, L.2
Catala, A.I.3
-
91
-
-
0346729968
-
Ceramide content is increased in skeletal muscle from obese insulin-resistant humans
-
Adams, J.M., II; Pratipanawatr, T.; Berria, R.; Wang, E.; DeFronzo, R.A.; Sullards, M.C.; Mandarino, L.J. Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. Diabetes 2004, 53, 25-31.
-
(2004)
Diabetes
, vol.53
, pp. 25-31
-
-
Adams II, J.M.1
Pratipanawatr, T.2
Berria, R.3
Wang, E.4
DeFronzo, R.A.5
Sullards, M.C.6
Mandarino, L.J.7
-
92
-
-
34248205140
-
Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity
-
Aerts, J.M.; Ottenhoff, R.; Powlson, A.S.; Grefhorst, A.; van Eijk, M.; Dubbelhuis, P.F.; Aten, J.; Kuipers, F.; Serlie, M.J.; Wennekes, T.; Sethi, J.K.; O'Rahilly, S.; Overkleeft, H.S. Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity. Diabetes 2007, 56, 1341-1349.
-
(2007)
Diabetes
, vol.56
, pp. 1341-1349
-
-
Aerts, J.M.1
Ottenhoff, R.2
Powlson, A.S.3
Grefhorst, A.4
van Eijk, M.5
Dubbelhuis, P.F.6
Aten, J.7
Kuipers, F.8
Serlie, M.J.9
Wennekes, T.10
Sethi, J.K.11
O'Rahilly, S.12
Overkleeft, H.S.13
-
93
-
-
33847026801
-
Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells
-
JeBailey, L.; Wanono, O.; Niu, W.; Roessler, J.; Rudich, A.; Klip, A. Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells. Diabetes 2007, 56, 394-403.
-
(2007)
Diabetes
, vol.56
, pp. 394-403
-
-
JeBailey, L.1
Wanono, O.2
Niu, W.3
Roessler, J.4
Rudich, A.5
Klip, A.6
-
94
-
-
0033588253
-
Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate
-
Schmitz-Peiffer, C.; Craig, D.L.; Biden, T.J. Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate. J. Biol. Chem. 1999, 274, 24202-24210.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 24202-24210
-
-
Schmitz-Peiffer, C.1
Craig, D.L.2
Biden, T.J.3
-
95
-
-
0035513703
-
Ceramide mediates insulin resistance by tumor necrosis factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state
-
Teruel, T.; Hernandez, R.; Lorenzo, M. Ceramide mediates insulin resistance by tumor necrosis factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state. Diabetes 2001, 50, 2563-25671.
-
(2001)
Diabetes
, vol.50
, pp. 2563-25671
-
-
Teruel, T.1
Hernandez, R.2
Lorenzo, M.3
-
96
-
-
67649723058
-
Mechanisms of ceramide-mediated neurodegeneration
-
Tong, M.; de la Monte, S.M. Mechanisms of ceramide-mediated neurodegeneration. J. Alzheimers Dis. 2009, 16, 705-714.
-
(2009)
J. Alzheimers Dis
, vol.16
, pp. 705-714
-
-
Tong, M.1
de la Monte, S.M.2
-
97
-
-
26644468852
-
The neuropsychological profile of alcohol-related dementia suggests cortical and subcortical pathology
-
Schmidt, K.S.; Gallo, J.L.; Ferri, C.; Giovannetti, T.; Sestito, N.; Libon, D.J.; Schmidt, P.S. The neuropsychological profile of alcohol-related dementia suggests cortical and subcortical pathology. Dement. Geriatr. Cogn. Disord 2005, 20, 286-291.
-
(2005)
Dement. Geriatr. Cogn. Disord
, vol.20
, pp. 286-291
-
-
Schmidt, K.S.1
Gallo, J.L.2
Ferri, C.3
Giovannetti, T.4
Sestito, N.5
Libon, D.J.6
Schmidt, P.S.7
-
98
-
-
61449257436
-
The Korsakoff syndrome: Clinical aspects, psychology and treatment
-
Kopelman, M.D.; Thomson, A.D.; Guerrini, I.; Marshall, E.J. The Korsakoff syndrome: clinical aspects, psychology and treatment. Alcohol Alcoholism 2009, 44, 148-154.
-
(2009)
Alcohol Alcoholism
, vol.44
, pp. 148-154
-
-
Kopelman, M.D.1
Thomson, A.D.2
Guerrini, I.3
Marshall, E.J.4
-
99
-
-
33748038468
-
Depression, anxiety, and nonalcoholic steatohepatitis
-
Elwing, J.E.; Lustman, P.J.; Wang, H.L.; Clouse, R.E. Depression, anxiety, and nonalcoholic steatohepatitis. Psychosom. Med. 2006, 68, 563-569.
-
(2006)
Psychosom. Med
, vol.68
, pp. 563-569
-
-
Elwing, J.E.1
Lustman, P.J.2
Wang, H.L.3
Clouse, R.E.4
-
100
-
-
38049153269
-
Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1beta and tumor necrosis factor-alpha
-
Loftis, J.M.; Huckans, M.; Ruimy, S.; Hinrichs, D.J.; Hauser, P. Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1beta and tumor necrosis factor-alpha. Neurosci. Lett. 2008, 430, 264-268.
-
(2008)
Neurosci. Lett
, vol.430
, pp. 264-268
-
-
Loftis, J.M.1
Huckans, M.2
Ruimy, S.3
Hinrichs, D.J.4
Hauser, P.5
-
101
-
-
38649108842
-
Cognitive dysfunction in chronic hepatitis C: A review
-
Perry, W.; Hilsabeck, R.C.; Hassanein, T.I. Cognitive dysfunction in chronic hepatitis C: a review. Dig. Dis. Sci. 2008, 53, 307-321.
-
(2008)
Dig. Dis. Sci
, vol.53
, pp. 307-321
-
-
Perry, W.1
Hilsabeck, R.C.2
Hassanein, T.I.3
-
102
-
-
34447320467
-
Neuropsychological function in Greek patients with chronic hepatitis C
-
Karaivazoglou, K.; Assimakopoulos, K.; Thomopoulos, K.; Theocharis, G.; Messinis, L.; Sakellaropoulos, G.; Labropoulou-Karatza, C. Neuropsychological function in Greek patients with chronic hepatitis C. Liver Int. 2007, 27, 798-805.
-
(2007)
Liver Int
, vol.27
, pp. 798-805
-
-
Karaivazoglou, K.1
Assimakopoulos, K.2
Thomopoulos, K.3
Theocharis, G.4
Messinis, L.5
Sakellaropoulos, G.6
Labropoulou-Karatza, C.7
-
103
-
-
33750492618
-
-
Psychiatric behavioral aspects of comanagement of hepatitis C virus and HIV
-
Weiss, J.J.; Gorman, J.M. Psychiatric behavioral aspects of comanagement of hepatitis C virus and HIV. Curr. HIV/AIDS Rep. 2006, 3, 176-181.
-
(2006)
HIV/AIDS Rep
, vol.3
, pp. 176-181
-
-
Weiss, J.J.1
Gorman, J.M.2
-
104
-
-
33748755428
-
Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease
-
de la Monte, S.M.; Tong, M.; Lester-Coll, N.; Plater, M., Jr.; Wands, J.R. Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease. J. Alzheimers Dis. 2006, 10, 89-109.
-
(2006)
J. Alzheimers Dis
, vol.10
, pp. 89-109
-
-
de la Monte, S.M.1
Tong, M.2
Lester-Coll, N.3
Plater Jr., M.4
Wands, J.R.5
-
105
-
-
33645960672
-
Intracerebral streptozotocin model of type 3 diabetes: Relevance to sporadic Alzheimer's disease
-
Lester-Coll, N.; Rivera, E.J.; Soscia, S.J.; Doiron, K.; Wands, J.R.; de la Monte, S.M. Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease. J. Alzheimers Dis. 2006, 9, 13-33.
-
(2006)
J. Alzheimers Dis
, vol.9
, pp. 13-33
-
-
Lester-Coll, N.1
Rivera, E.J.2
Soscia, S.J.3
Doiron, K.4
Wands, J.R.5
de la Monte, S.M.6
-
106
-
-
68249109031
-
Nitrosamine-mediated type 2 diabetes mellitus, hepatic steatosis, and alzheimer-type neurodegeneration: Potential role of environmental exposures in our insulin resistance diseases pandemic
-
In Press
-
Tong, M.; Lawton, M.; Neusner, A.; Longato, L.; Wands, J.R.; de la Monte, S.M. Nitrosamine-mediated type 2 diabetes mellitus, hepatic steatosis, and alzheimer-type neurodegeneration: Potential role of environmental exposures in our insulin resistance diseases pandemic. J. Alzheimers Dis. 2009, (In Press).
-
(2009)
J. Alzheimers Dis
-
-
Tong, M.1
Lawton, M.2
Neusner, A.3
Longato, L.4
Wands, J.R.5
de la Monte, S.M.6
-
107
-
-
68249100361
-
Hepatic ceramide mediates brain insulin resistance and neurodegeneration in obesity with type 2 diabetes mellitus and Non-alcoholoic steatohepatitis
-
Submitted
-
Lyn-Cook, L.E.; Lawton, M.; Tong, M.; Silbermann, E.; Longato, L.; Jiao, P.; Mark, P.; Wands, J.R.; Xu, H.; de la Monte, S.M. Hepatic ceramide mediates brain insulin resistance and neurodegeneration in obesity with type 2 diabetes mellitus and Non-alcoholoic steatohepatitis. J. Alzheimers Dis. 2008, (Submitted).
-
(2008)
J. Alzheimers Dis
-
-
Lyn-Cook, L.E.1
Lawton, M.2
Tong, M.3
Silbermann, E.4
Longato, L.5
Jiao, P.6
Mark, P.7
Wands, J.R.8
Xu, H.9
de la Monte, S.M.10
-
108
-
-
52449087540
-
-
Moroz, N.; Tong, M.; Longato, L.; Xu, H.; de la Monte, S.M. Limited Alzheimer-type neurodegeneration in experimental obesity and Type 2 diabetes mellitus. J. Alzheimers Dis. 2008, 15, 29-44.
-
Moroz, N.; Tong, M.; Longato, L.; Xu, H.; de la Monte, S.M. Limited Alzheimer-type neurodegeneration in experimental obesity and Type 2 diabetes mellitus. J. Alzheimers Dis. 2008, 15, 29-44.
-
-
-
-
109
-
-
68249130630
-
Nitrosamine exposure exacerbates high fat diet-mediated neurodegeneration
-
BMC Cell Biol
-
Tong, M.; Longato, L.; de la Monte, S.M. Nitrosamine exposure exacerbates high fat diet-mediated neurodegeneration. BMC Cell Biol. 2009, (Under Review).
-
(2009)
Under Review
-
-
Tong, M.1
Longato, L.2
de la Monte, S.M.3
-
110
-
-
68249127000
-
Nitrosamine Exposure Causes Insulin Resistance Diseases: Relevance to Type 2 Diabetes Mellitus, Non-Alcoholic Steatohepatitis, and Alzheimer's Disease
-
Jun 19, Epub ahead of print
-
Tong, M.; Neusner, A.; Longato, L.; Lawton, M.; Wands, J.R.; de la Monte, S.M. Nitrosamine Exposure Causes Insulin Resistance Diseases: Relevance to Type 2 Diabetes Mellitus, Non-Alcoholic Steatohepatitis, and Alzheimer's Disease. J. Alzheimers Dis. 2009, Jun 19, (Epub ahead of print).
-
(2009)
J. Alzheimers Dis
-
-
Tong, M.1
Neusner, A.2
Longato, L.3
Lawton, M.4
Wands, J.R.5
de la Monte, S.M.6
-
111
-
-
68249127000
-
Nitosamine exposure causes insulin resistance diseases: Relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer disease
-
In Press
-
Tong, M.; Neusner, A.; Longato, L.; Lawton, M.; Wands, J.R.; de la Monte, S.M. Nitosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer disease. J. Alzheimers Dis. 2009, (In Press).
-
(2009)
J. Alzheimers Dis
-
-
Tong, M.1
Neusner, A.2
Longato, L.3
Lawton, M.4
Wands, J.R.5
de la Monte, S.M.6
-
112
-
-
34250004321
-
Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells
-
Arboleda, G.; Huang, T.J.; Waters, C.; Verkhratsky, A.; Fernyhough, P.; Gibson, R.M. Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells. Eur. J. Neurosci. 2007, 25, 3030-3038.
-
(2007)
Eur. J. Neurosci
, vol.25
, pp. 3030-3038
-
-
Arboleda, G.1
Huang, T.J.2
Waters, C.3
Verkhratsky, A.4
Fernyhough, P.5
Gibson, R.M.6
-
113
-
-
0033575310
-
Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid
-
Chalfant, C.E.; Kishikawa, K.; Mumby, M.C.; Kamibayashi, C.; Bielawska, A.; Hannun, Y.A. Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid. J. Biol. Chem. 1999, 274, 20313-20317.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 20313-20317
-
-
Chalfant, C.E.1
Kishikawa, K.2
Mumby, M.C.3
Kamibayashi, C.4
Bielawska, A.5
Hannun, Y.A.6
-
114
-
-
0000993166
-
Sphingomyelinases in cell regulation
-
Liu, B.; Obeid, L.M.; Hannun, Y.A. Sphingomyelinases in cell regulation. Semin. Cell Dev. Biol. 1997, 8, 311-322.
-
(1997)
Semin. Cell Dev. Biol
, vol.8
, pp. 311-322
-
-
Liu, B.1
Obeid, L.M.2
Hannun, Y.A.3
-
115
-
-
50049121874
-
Regulation and functions of sphingosine kinases in the brain
-
Bryan, L.; Kordula, T.; Spiegel, S.; Milstien, S. Regulation and functions of sphingosine kinases in the brain. Biochim. Biophys. Acta 2008, 1781, 459-466.
-
(2008)
Biochim. Biophys. Acta
, vol.1781
, pp. 459-466
-
-
Bryan, L.1
Kordula, T.2
Spiegel, S.3
Milstien, S.4
-
116
-
-
35048824758
-
Sphingolipid signaling pathways as potential therapeutic targets in gliomas
-
Van Brocklyn, J.R. Sphingolipid signaling pathways as potential therapeutic targets in gliomas. Mini. Rev. Med. Chem. 2007, 7, 984-990.
-
(2007)
Mini. Rev. Med. Chem
, vol.7
, pp. 984-990
-
-
Van Brocklyn, J.R.1
|