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Volumn 10, Issue , 2010, Pages

Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; CERAMIDE; CHOLINE ACETYLTRANSFERASE; DIETHYLNITROSAMINE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE; SOMATOMEDIN; SOMATOMEDIN B RECEPTOR; TAU PROTEIN;

EID: 77953004836     PISSN: None     EISSN: 14726823     Source Type: Journal    
DOI: 10.1186/1472-6823-10-4     Document Type: Article
Times cited : (52)

References (117)
  • 1
    • 39649092297 scopus 로고    scopus 로고
    • Obesity, metabolic syndrome, and type 2 diabetes: inflammatory basis of glucose metabolic disorders
    • 10.1111/j.1753-4887.2007.tb00354.x, 18240540
    • Pradhan A. Obesity, metabolic syndrome, and type 2 diabetes: inflammatory basis of glucose metabolic disorders. Nutr Rev 2007, 65(12 Pt 2):S152-156. 10.1111/j.1753-4887.2007.tb00354.x, 18240540.
    • (2007) Nutr Rev , vol.65 , Issue.12 PART 2
    • Pradhan, A.1
  • 2
    • 34147151118 scopus 로고    scopus 로고
    • Next steps in Alzheimer's disease research: interaction between epidemiology and basic science
    • 10.2174/156720507780362155, 17430237
    • Launer LJ. Next steps in Alzheimer's disease research: interaction between epidemiology and basic science. Curr Alzheimer Res 2007, 4(2):141-143. 10.2174/156720507780362155, 17430237.
    • (2007) Curr Alzheimer Res , vol.4 , Issue.2 , pp. 141-143
    • Launer, L.J.1
  • 3
    • 44349117318 scopus 로고    scopus 로고
    • Alzheimer's disease: epidemiology, genetics, and beyond
    • 10.1007/s12264-008-0105-7, 18369390
    • Wang XP, Ding HL. Alzheimer's disease: epidemiology, genetics, and beyond. Neurosci Bull 2008, 24(2):105-109. 10.1007/s12264-008-0105-7, 18369390.
    • (2008) Neurosci Bull , vol.24 , Issue.2 , pp. 105-109
    • Wang, X.P.1    Ding, H.L.2
  • 4
    • 67849085394 scopus 로고    scopus 로고
    • Epidemilogical Trends Strongly Suggest Exposures as Etiologic Agents in the Pathogenesis of Sporadic Alzheimer's Disease, Diabetes Mellitus, and Non-Alcoholic Steatohepatitis
    • de la Monte SM, Neusner A, Chu J, Lawton M. Epidemilogical Trends Strongly Suggest Exposures as Etiologic Agents in the Pathogenesis of Sporadic Alzheimer's Disease, Diabetes Mellitus, and Non-Alcoholic Steatohepatitis. J Alzheimers Dis 2009, 17(3):519-529.
    • (2009) J Alzheimers Dis , vol.17 , Issue.3 , pp. 519-529
    • de la Monte, S.M.1    Neusner, A.2    Chu, J.3    Lawton, M.4
  • 5
    • 0014355386 scopus 로고
    • Nitrosamine-induced carcinogenesis. The alklylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate
    • 1187106, 5722690
    • Swann PF, Magee PN. Nitrosamine-induced carcinogenesis. The alklylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate. Biochem J 1968, 110(1):39-47. 1187106, 5722690.
    • (1968) Biochem J , vol.110 , Issue.1 , pp. 39-47
    • Swann, P.F.1    Magee, P.N.2
  • 6
    • 0036273095 scopus 로고    scopus 로고
    • A chemical perspective on the interplay between NO, reactive oxygen species, and reactive nitrogen oxide species
    • 10.1111/j.1749-6632.2002.tb04068.x, 12076975
    • Espey MG, Miranda KM, Thomas DD, Xavier S, Citrin D, Vitek MP, Wink DA. A chemical perspective on the interplay between NO, reactive oxygen species, and reactive nitrogen oxide species. Ann N Y Acad Sci 2002, 962:195-206. 10.1111/j.1749-6632.2002.tb04068.x, 12076975.
    • (2002) Ann N Y Acad Sci , vol.962 , pp. 195-206
    • Espey, M.G.1    Miranda, K.M.2    Thomas, D.D.3    Xavier, S.4    Citrin, D.5    Vitek, M.P.6    Wink, D.A.7
  • 7
    • 33751570625 scopus 로고    scopus 로고
    • Diabetes mellitus and dementia
    • 10.1016/S1262-3636(07)70298-7, 17110895
    • Pasquier F, Boulogne A, Leys D, Fontaine P. Diabetes mellitus and dementia. Diabetes Metab 2006, 32(5 Pt 1):403-414. 10.1016/S1262-3636(07)70298-7, 17110895.
    • (2006) Diabetes Metab , vol.32 , Issue.5 PART 1 , pp. 403-414
    • Pasquier, F.1    Boulogne, A.2    Leys, D.3    Fontaine, P.4
  • 8
    • 23044442730 scopus 로고    scopus 로고
    • The clinical and biological relationship between Type II diabetes mellitus and Alzheimer's disease
    • 10.2174/1567205043480555, 15975085
    • Nicolls MR. The clinical and biological relationship between Type II diabetes mellitus and Alzheimer's disease. Curr Alzheimer Res 2004, 1(1):47-54. 10.2174/1567205043480555, 15975085.
    • (2004) Curr Alzheimer Res , vol.1 , Issue.1 , pp. 47-54
    • Nicolls, M.R.1
  • 9
    • 36249009634 scopus 로고    scopus 로고
    • Pathology of nonalcoholic fatty liver disease
    • 10.1309/RTPM1PY6YGBL2G2R, 17951208
    • Yeh MM, Brunt EM. Pathology of nonalcoholic fatty liver disease. Am J Clin Pathol 2007, 128(5):837-847. 10.1309/RTPM1PY6YGBL2G2R, 17951208.
    • (2007) Am J Clin Pathol , vol.128 , Issue.5 , pp. 837-847
    • Yeh, M.M.1    Brunt, E.M.2
  • 10
    • 34249711303 scopus 로고    scopus 로고
    • Metabolic syndrome and NASH
    • ix, 10.1016/j.cld.2007.02.013, 17544974
    • Marchesini G, Marzocchi R. Metabolic syndrome and NASH. Clin Liver Dis 2007, 11(1):105-117. ix, 10.1016/j.cld.2007.02.013, 17544974.
    • (2007) Clin Liver Dis , vol.11 , Issue.1 , pp. 105-117
    • Marchesini, G.1    Marzocchi, R.2
  • 11
    • 34447633011 scopus 로고    scopus 로고
    • Update on non-alcoholic fatty liver disease in children
    • 10.1016/j.clnu.2007.02.002, 17449148
    • Papandreou D, Rousso I, Mavromichalis I. Update on non-alcoholic fatty liver disease in children. Clin Nutr 2007, 26(4):409-415. 10.1016/j.clnu.2007.02.002, 17449148.
    • (2007) Clin Nutr , vol.26 , Issue.4 , pp. 409-415
    • Papandreou, D.1    Rousso, I.2    Mavromichalis, I.3
  • 12
    • 34249792393 scopus 로고    scopus 로고
    • Role of mitochondria in non-alcoholic fatty liver disease
    • 10.1111/j.1440-1746.2006.04640.x, 17567459
    • Pessayre D. Role of mitochondria in non-alcoholic fatty liver disease. J Gastroenterol Hepatol 2007, 22(Suppl 1):S20-27. 10.1111/j.1440-1746.2006.04640.x, 17567459.
    • (2007) J Gastroenterol Hepatol , vol.22 , Issue.SUPPL. 1
    • Pessayre, D.1
  • 13
    • 39849091969 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and mitochondrial dysfunction
    • 10.3748/wjg.14.193, 2675113, 18186554
    • Wei Y, Rector RS, Thyfault JP, Ibdah JA. Nonalcoholic fatty liver disease and mitochondrial dysfunction. World J Gastroenterol 2008, 14(2):193-199. 10.3748/wjg.14.193, 2675113, 18186554.
    • (2008) World J Gastroenterol , vol.14 , Issue.2 , pp. 193-199
    • Wei, Y.1    Rector, R.S.2    Thyfault, J.P.3    Ibdah, J.A.4
  • 14
    • 0036898999 scopus 로고    scopus 로고
    • Genotoxicity of streptozotocin
    • 10.1016/S1383-5742(02)00044-3, 12464347
    • Bolzan AD, Bianchi MS. Genotoxicity of streptozotocin. Mutat Res 2002, 512(2-3):121-134. 10.1016/S1383-5742(02)00044-3, 12464347.
    • (2002) Mutat Res , vol.512 , Issue.2-3 , pp. 121-134
    • Bolzan, A.D.1    Bianchi, M.S.2
  • 15
    • 0017648112 scopus 로고
    • Studies of streptozotocin-induced insulitis and diabetes
    • 10.1073/pnas.74.6.2485, 432197, 142253
    • Rossini AA, Like AA, Chick WL, Appel MC, Cahill GF. Studies of streptozotocin-induced insulitis and diabetes. Proc Natl Acad Sci USA 1977, 74(6):2485-2489. 10.1073/pnas.74.6.2485, 432197, 142253.
    • (1977) Proc Natl Acad Sci USA , vol.74 , Issue.6 , pp. 2485-2489
    • Rossini, A.A.1    Like, A.A.2    Chick, W.L.3    Appel, M.C.4    Cahill, G.F.5
  • 16
    • 0035691617 scopus 로고    scopus 로고
    • The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas
    • Szkudelski T. The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 2001, 50(6):537-546.
    • (2001) Physiol Res , vol.50 , Issue.6 , pp. 537-546
    • Szkudelski, T.1
  • 17
    • 0016857569 scopus 로고
    • [Studies on the mechanism of the diabetogenic activity of streptozotocin and on the ability of compounds to block the diabetogenic activity of streptozotocin (author's transl)]
    • Doi K. [Studies on the mechanism of the diabetogenic activity of streptozotocin and on the ability of compounds to block the diabetogenic activity of streptozotocin (author's transl)]. Nippon Naibunpi Gakkai Zasshi 1975, 51(3):129-147.
    • (1975) Nippon Naibunpi Gakkai Zasshi , vol.51 , Issue.3 , pp. 129-147
    • Doi, K.1
  • 18
    • 33845655596 scopus 로고    scopus 로고
    • High sensitivity of fatty liver Shionogi (FLS) mice to diethylnitrosamine hepatocarcinogenesis: comparison to C3H and C57 mice
    • 10.1016/j.canlet.2006.02.008, 16569478
    • Iwai S, Murai T, Makino S, Min W, Morimura K, Mori S, Hagihara A, Seki S, Fukushima S. High sensitivity of fatty liver Shionogi (FLS) mice to diethylnitrosamine hepatocarcinogenesis: comparison to C3H and C57 mice. Cancer Lett 2007, 246(1-2):115-121. 10.1016/j.canlet.2006.02.008, 16569478.
    • (2007) Cancer Lett , vol.246 , Issue.1-2 , pp. 115-121
    • Iwai, S.1    Murai, T.2    Makino, S.3    Min, W.4    Morimura, K.5    Mori, S.6    Hagihara, A.7    Seki, S.8    Fukushima, S.9
  • 19
    • 33748755428 scopus 로고    scopus 로고
    • Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease
    • de la Monte SM, Tong M, Lester-Coll N, Plater M, Wands JR. Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease. J Alzheimers Dis 2006, 10(1):89-109.
    • (2006) J Alzheimers Dis , vol.10 , Issue.1 , pp. 89-109
    • de la Monte, S.M.1    Tong, M.2    Lester-Coll, N.3    Plater, M.4    Wands, J.R.5
  • 20
    • 0347654897 scopus 로고    scopus 로고
    • Causes and consequences of disturbances of cerebral glucose metabolism in sporadic Alzheimer disease: therapeutic implications
    • Hoyer S. Causes and consequences of disturbances of cerebral glucose metabolism in sporadic Alzheimer disease: therapeutic implications. Adv Exp Med Biol 2004, 541:135-152.
    • (2004) Adv Exp Med Biol , vol.541 , pp. 135-152
    • Hoyer, S.1
  • 21
    • 0033460182 scopus 로고    scopus 로고
    • Damaged neuronal energy metabolism and behavior are improved by Ginkgo biloba extract (EGb 761)
    • 10.1007/s007020050232, 10651112
    • Hoyer S, Lannert H, Noldner M, Chatterjee SS. Damaged neuronal energy metabolism and behavior are improved by Ginkgo biloba extract (EGb 761). J Neural Transm 1999, 106(11-12):1171-1188. 10.1007/s007020050232, 10651112.
    • (1999) J Neural Transm , vol.106 , Issue.11-12 , pp. 1171-1188
    • Hoyer, S.1    Lannert, H.2    Noldner, M.3    Chatterjee, S.S.4
  • 23
    • 0033561597 scopus 로고    scopus 로고
    • Site-specific DNA methylation and apoptosis: induction by diabetogenic streptozotocin
    • 10.1016/S0006-2952(98)00370-0, 10086321
    • Murata M, Takahashi A, Saito I, Kawanishi S. Site-specific DNA methylation and apoptosis: induction by diabetogenic streptozotocin. Biochem Pharmacol 1999, 57(8):881-887. 10.1016/S0006-2952(98)00370-0, 10086321.
    • (1999) Biochem Pharmacol , vol.57 , Issue.8 , pp. 881-887
    • Murata, M.1    Takahashi, A.2    Saito, I.3    Kawanishi, S.4
  • 24
    • 0023820924 scopus 로고
    • Enhancement by streptozotocin of O2- radical generation by the xanthine oxidase system of pancreatic beta-cells
    • 10.1016/0014-5793(88)80938-4, 2846360
    • Nukatsuka M, Sakurai H, Yoshimura Y, Nishida M, Kawada J. Enhancement by streptozotocin of O2- radical generation by the xanthine oxidase system of pancreatic beta-cells. FEBS Lett 1988, 239(2):295-298. 10.1016/0014-5793(88)80938-4, 2846360.
    • (1988) FEBS Lett , vol.239 , Issue.2 , pp. 295-298
    • Nukatsuka, M.1    Sakurai, H.2    Yoshimura, Y.3    Nishida, M.4    Kawada, J.5
  • 25
    • 0033994409 scopus 로고    scopus 로고
    • Radicals and oxidative stress in diabetes
    • 10.1046/j.1464-5491.2000.00259.x, 10784220
    • West IC. Radicals and oxidative stress in diabetes. Diabet Med 2000, 17(3):171-180. 10.1046/j.1464-5491.2000.00259.x, 10784220.
    • (2000) Diabet Med , vol.17 , Issue.3 , pp. 171-180
    • West, I.C.1
  • 26
    • 0029887466 scopus 로고    scopus 로고
    • DNA damage induced by seven N-nitroso compounds in primary cultures of human and rat kidney cells
    • 10.1016/S0165-1218(96)90038-5, 8637509
    • Robbiano L, Mereto E, Corbu C, Brambilla G. DNA damage induced by seven N-nitroso compounds in primary cultures of human and rat kidney cells. Mutat Res 1996, 368(1):41-47. 10.1016/S0165-1218(96)90038-5, 8637509.
    • (1996) Mutat Res , vol.368 , Issue.1 , pp. 41-47
    • Robbiano, L.1    Mereto, E.2    Corbu, C.3    Brambilla, G.4
  • 28
    • 33746565284 scopus 로고    scopus 로고
    • Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease
    • 10.1038/sj.mp.4001854, 16786033
    • Martins IJ, Hone E, Foster JK, Sunram-Lea SI, Gnjec A, Fuller SJ, Nolan D, Gandy SE, Martins RN. Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease. Mol Psychiatry 2006, 11(8):721-736. 10.1038/sj.mp.4001854, 16786033.
    • (2006) Mol Psychiatry , vol.11 , Issue.8 , pp. 721-736
    • Martins, I.J.1    Hone, E.2    Foster, J.K.3    Sunram-Lea, S.I.4    Gnjec, A.5    Fuller, S.J.6    Nolan, D.7    Gandy, S.E.8    Martins, R.N.9
  • 29
    • 33644591150 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine
    • Rivera EJ, Goldin A, Fulmer N, Tavares R, Wands JR, de la Monte SM. Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine. J Alzheimers Dis 2005, 8(3):247-268.
    • (2005) J Alzheimers Dis , vol.8 , Issue.3 , pp. 247-268
    • Rivera, E.J.1    Goldin, A.2    Fulmer, N.3    Tavares, R.4    Wands, J.R.5    de la Monte, S.M.6
  • 31
    • 34147173277 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment
    • 10.2174/156720507780362137, 17430239
    • Craft S. Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment. Curr Alzheimer Res 2007, 4(2):147-152. 10.2174/156720507780362137, 17430239.
    • (2007) Curr Alzheimer Res , vol.4 , Issue.2 , pp. 147-152
    • Craft, S.1
  • 32
    • 33845468713 scopus 로고    scopus 로고
    • Insulin resistance syndrome and Alzheimer disease: pathophysiologic mechanisms and therapeutic implications
    • 10.1097/01.wad.0000213866.86934.7e, 17132977
    • Craft S. Insulin resistance syndrome and Alzheimer disease: pathophysiologic mechanisms and therapeutic implications. Alzheimer Dis Assoc Disord 2006, 20(4):298-301. 10.1097/01.wad.0000213866.86934.7e, 17132977.
    • (2006) Alzheimer Dis Assoc Disord , vol.20 , Issue.4 , pp. 298-301
    • Craft, S.1
  • 33
    • 28444459843 scopus 로고    scopus 로고
    • Studies of the effects of high fat diets on cognitive function in a rat model
    • 10.1016/j.neurobiolaging.2005.09.003, 16219391
    • Winocur G, Greenwood CE. Studies of the effects of high fat diets on cognitive function in a rat model. Neurobiol Aging 2005, 26(Suppl 1):46-49. 10.1016/j.neurobiolaging.2005.09.003, 16219391.
    • (2005) Neurobiol Aging , vol.26 , Issue.SUPPL. 1 , pp. 46-49
    • Winocur, G.1    Greenwood, C.E.2
  • 34
    • 27744486073 scopus 로고    scopus 로고
    • Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity
    • 10.1037/0735-7044.119.5.1389, 16300445
    • Winocur G, Greenwood CE, Piroli GG, Grillo CA, Reznikov LR, Reagan LP, McEwen BS. Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity. Behav Neurosci 2005, 119(5):1389-1395. 10.1037/0735-7044.119.5.1389, 16300445.
    • (2005) Behav Neurosci , vol.119 , Issue.5 , pp. 1389-1395
    • Winocur, G.1    Greenwood, C.E.2    Piroli, G.G.3    Grillo, C.A.4    Reznikov, L.R.5    Reagan, L.P.6    McEwen, B.S.7
  • 35
    • 1542343843 scopus 로고    scopus 로고
    • Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity
    • 10.1007/s00702-003-0058-y, 14991459
    • Weinstock M, Shoham S. Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity. J Neural Transm 2004, 111(3):347-366. 10.1007/s00702-003-0058-y, 14991459.
    • (2004) J Neural Transm , vol.111 , Issue.3 , pp. 347-366
    • Weinstock, M.1    Shoham, S.2
  • 36
    • 0036715390 scopus 로고    scopus 로고
    • Diabetic neuropathies in brain are induced by deficiency of BDNF
    • 10.1016/S0892-0362(02)00220-9, 12200200
    • Nitta A, Murai R, Suzuki N, Ito H, Nomoto H, Katoh G, Furukawa Y, Furukawa S. Diabetic neuropathies in brain are induced by deficiency of BDNF. Neurotoxicol Teratol 2002, 24(5):695-701. 10.1016/S0892-0362(02)00220-9, 12200200.
    • (2002) Neurotoxicol Teratol , vol.24 , Issue.5 , pp. 695-701
    • Nitta, A.1    Murai, R.2    Suzuki, N.3    Ito, H.4    Nomoto, H.5    Katoh, G.6    Furukawa, Y.7    Furukawa, S.8
  • 37
    • 0031886832 scopus 로고    scopus 로고
    • Brain glutamate dehydrogenase changes in streptozotocin diabetic rats as a function of age
    • Biju MP, Paulose CS. Brain glutamate dehydrogenase changes in streptozotocin diabetic rats as a function of age. Biochem Mol Biol Int 1998, 44(1):1-7.
    • (1998) Biochem Mol Biol Int , vol.44 , Issue.1 , pp. 1-7
    • Biju, M.P.1    Paulose, C.S.2
  • 38
    • 33644585223 scopus 로고    scopus 로고
    • Therapy Insight: type 2 diabetes mellitus and the risk of late-onset Alzheimer's disease
    • 10.1038/ncpneuro0124, 16932542
    • Haan MN. Therapy Insight: type 2 diabetes mellitus and the risk of late-onset Alzheimer's disease. Nat Clin Pract Neurol 2006, 2(3):159-166. 10.1038/ncpneuro0124, 16932542.
    • (2006) Nat Clin Pract Neurol , vol.2 , Issue.3 , pp. 159-166
    • Haan, M.N.1
  • 40
    • 34147102288 scopus 로고    scopus 로고
    • Therapeutic use of agonists of the nuclear receptor PPARgamma in Alzheimer's disease
    • 10.2174/156720507780362092, 17430241
    • Landreth G. Therapeutic use of agonists of the nuclear receptor PPARgamma in Alzheimer's disease. Curr Alzheimer Res 2007, 4(2):159-164. 10.2174/156720507780362092, 17430241.
    • (2007) Curr Alzheimer Res , vol.4 , Issue.2 , pp. 159-164
    • Landreth, G.1
  • 42
    • 33846148284 scopus 로고    scopus 로고
    • Intranasal insulin administration: a method for dissociating central and peripheral effects of insulin
    • 10.1358/dot.2006.42.11.1007675, 17171192
    • Reger MA, Craft S. Intranasal insulin administration: a method for dissociating central and peripheral effects of insulin. Drugs Today (Barc) 2006, 42(11):729-739. 10.1358/dot.2006.42.11.1007675, 17171192.
    • (2006) Drugs Today (Barc) , vol.42 , Issue.11 , pp. 729-739
    • Reger, M.A.1    Craft, S.2
  • 44
    • 33745234766 scopus 로고    scopus 로고
    • Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice
    • 10.1016/j.expneurol.2006.01.018, 16515786
    • Pedersen WA, McMillan PJ, Kulstad JJ, Leverenz JB, Craft S, Haynatzki GR. Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice. Exp Neurol 2006, 199(2):265-273. 10.1016/j.expneurol.2006.01.018, 16515786.
    • (2006) Exp Neurol , vol.199 , Issue.2 , pp. 265-273
    • Pedersen, W.A.1    McMillan, P.J.2    Kulstad, J.J.3    Leverenz, J.B.4    Craft, S.5    Haynatzki, G.R.6
  • 46
    • 52449087540 scopus 로고    scopus 로고
    • Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus
    • Moroz N, Tong M, Longato L, Xu H, de la Monte SM. Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus. J Alzheimers Dis 2008, 15(1):29-44.
    • (2008) J Alzheimers Dis , vol.15 , Issue.1 , pp. 29-44
    • Moroz, N.1    Tong, M.2    Longato, L.3    Xu, H.4    de la Monte, S.M.5
  • 47
    • 0029942905 scopus 로고    scopus 로고
    • The relationship of multiple system atrophy to sporadic olivopontocerebellar atrophy and other forms of idiopathic late-onset cerebellar atrophy
    • Gilman S, Quinn NP. The relationship of multiple system atrophy to sporadic olivopontocerebellar atrophy and other forms of idiopathic late-onset cerebellar atrophy. Neurology 1996, 46(5):1197-1199.
    • (1996) Neurology , vol.46 , Issue.5 , pp. 1197-1199
    • Gilman, S.1    Quinn, N.P.2
  • 48
    • 0030040304 scopus 로고    scopus 로고
    • Spinocerebellar ataxia type 1 with multiple system degeneration and glial cytoplasmic inclusions
    • 10.1002/ana.410390214, 8967756
    • Gilman S, Sima AA, Junck L, Kluin KJ, Koeppe RA, Lohman ME, Little R. Spinocerebellar ataxia type 1 with multiple system degeneration and glial cytoplasmic inclusions. Ann Neurol 1996, 39(2):241-255. 10.1002/ana.410390214, 8967756.
    • (1996) Ann Neurol , vol.39 , Issue.2 , pp. 241-255
    • Gilman, S.1    Sima, A.A.2    Junck, L.3    Kluin, K.J.4    Koeppe, R.A.5    Lohman, M.E.6    Little, R.7
  • 50
    • 0032887585 scopus 로고    scopus 로고
    • Multiple system atrophy: a sporadic synucleinopathy
    • Dickson DW, Lin W, Liu WK, Yen SH. Multiple system atrophy: a sporadic synucleinopathy. Brain Pathol 1999, 9(4):721-732.
    • (1999) Brain Pathol , vol.9 , Issue.4 , pp. 721-732
    • Dickson, D.W.1    Lin, W.2    Liu, W.K.3    Yen, S.H.4
  • 51
    • 26444610170 scopus 로고    scopus 로고
    • Grading of neuropathology in multiple system atrophy: proposal for a novel scale
    • 10.1002/mds.20537, 16092088
    • Jellinger KA, Seppi K, Wenning GK. Grading of neuropathology in multiple system atrophy: proposal for a novel scale. Mov Disord 2005, 20(Suppl 12):S29-36. 10.1002/mds.20537, 16092088.
    • (2005) Mov Disord , vol.20 , Issue.SUPPL. 12
    • Jellinger, K.A.1    Seppi, K.2    Wenning, G.K.3
  • 52
    • 13844314087 scopus 로고    scopus 로고
    • Quantitative MRI measurement of superior cerebellar peduncle in progressive supranuclear palsy
    • Paviour DC, Price SL, Stevens JM, Lees AJ, Fox NC. Quantitative MRI measurement of superior cerebellar peduncle in progressive supranuclear palsy. Neurology 2005, 64(4):675-679.
    • (2005) Neurology , vol.64 , Issue.4 , pp. 675-679
    • Paviour, D.C.1    Price, S.L.2    Stevens, J.M.3    Lees, A.J.4    Fox, N.C.5
  • 53
    • 0020076144 scopus 로고
    • Olivopontocerebellar atrophy. A review of 117 cases
    • 10.1016/0022-510X(82)90011-9, 7057212
    • Berciano J. Olivopontocerebellar atrophy. A review of 117 cases. J Neurol Sci 1982, 53(2):253-272. 10.1016/0022-510X(82)90011-9, 7057212.
    • (1982) J Neurol Sci , vol.53 , Issue.2 , pp. 253-272
    • Berciano, J.1
  • 54
    • 0022363966 scopus 로고
    • [Neuropathological background of spinocerebellar degeneration--with special reference to autonomic nervous system lesions in olivopontocerebellar atrophy, Shy-Drager syndrome and multiple system atrophy]
    • Mizutani T. [Neuropathological background of spinocerebellar degeneration--with special reference to autonomic nervous system lesions in olivopontocerebellar atrophy, Shy-Drager syndrome and multiple system atrophy]. No To Shinkei 1985, 37(7):675-685.
    • (1985) No To Shinkei , vol.37 , Issue.7 , pp. 675-685
    • Mizutani, T.1
  • 56
    • 0020079794 scopus 로고
    • Regular involvement of Clarke's nucleus in sporadic amyotrophic lateral sclerosis
    • Averback P, Crocker P. Regular involvement of Clarke's nucleus in sporadic amyotrophic lateral sclerosis. Arch Neurol 1982, 39(3):155-156.
    • (1982) Arch Neurol , vol.39 , Issue.3 , pp. 155-156
    • Averback, P.1    Crocker, P.2
  • 58
    • 0030907583 scopus 로고    scopus 로고
    • The cerebellum in Alzheimer's disease
    • 10.1159/000106632, 9213064
    • Larner AJ. The cerebellum in Alzheimer's disease. Dement Geriatr Cogn Disord 1997, 8(4):203-209. 10.1159/000106632, 9213064.
    • (1997) Dement Geriatr Cogn Disord , vol.8 , Issue.4 , pp. 203-209
    • Larner, A.J.1
  • 61
    • 0030614372 scopus 로고    scopus 로고
    • Selective degeneration fo Purkinje cells with Lewy body-like inclusions in aged NFHLACZ transgenic mice
    • Tu PH, Robinson KA, de Snoo F, Eyer J, Peterson A, Lee VM, Trojanowski JQ. Selective degeneration fo Purkinje cells with Lewy body-like inclusions in aged NFHLACZ transgenic mice. J Neurosci 1997, 17(3):1064-1074.
    • (1997) J Neurosci , vol.17 , Issue.3 , pp. 1064-1074
    • Tu, P.H.1    Robinson, K.A.2    de Snoo, F.3    Eyer, J.4    Peterson, A.5    Lee, V.M.6    Trojanowski, J.Q.7
  • 64
    • 38049144345 scopus 로고    scopus 로고
    • [Multiple system atrophy and Alzheimer's disease: a case report of a rare association of two neuro-degenerative disorders]
    • Rusina R, Bourdain F, Matej R. [Multiple system atrophy and Alzheimer's disease: a case report of a rare association of two neuro-degenerative disorders]. Rev Neurol (Paris) 2007, 163(12):1239-1241.
    • (2007) Rev Neurol (Paris) , vol.163 , Issue.12 , pp. 1239-1241
    • Rusina, R.1    Bourdain, F.2    Matej, R.3
  • 65
    • 0033821237 scopus 로고    scopus 로고
    • Atypical dementia and spastic paraplegia in a patient with primary lateral sclerosis and numerous necortical beta amyloid plaques: new disorder or Alzheimer's disease variant?
    • 10.1177/089198870001300203, 10912726
    • Engel PA, Grunnet M. Atypical dementia and spastic paraplegia in a patient with primary lateral sclerosis and numerous necortical beta amyloid plaques: new disorder or Alzheimer's disease variant?. J Geriatr Psychiatry Neurol 2000, 13(2):60-64. 10.1177/089198870001300203, 10912726.
    • (2000) J Geriatr Psychiatry Neurol , vol.13 , Issue.2 , pp. 60-64
    • Engel, P.A.1    Grunnet, M.2
  • 66
    • 34447635411 scopus 로고    scopus 로고
    • The role of higher-level cognitive function in gait: executive dysfunction contributes to fall risk in Alzheimer's disease
    • 10.1159/000105126, 17622760
    • Sheridan PL, Hausdorff JM. The role of higher-level cognitive function in gait: executive dysfunction contributes to fall risk in Alzheimer's disease. Dement Geriatr Cogn Disord 2007, 24(2):125-137. 10.1159/000105126, 17622760.
    • (2007) Dement Geriatr Cogn Disord , vol.24 , Issue.2 , pp. 125-137
    • Sheridan, P.L.1    Hausdorff, J.M.2
  • 67
    • 52149119873 scopus 로고    scopus 로고
    • The cerebellum in mild cognitive impairment and Alzheimer's disease - a structural MRI study
    • 10.1016/j.jpsychires.2007.12.002, 18215400
    • Thomann PA, Schlafer C, Seidl U, Santos VD, Essig M, Schroder J. The cerebellum in mild cognitive impairment and Alzheimer's disease - a structural MRI study. J Psychiatr Res 2008, 42(14):1198-1202. 10.1016/j.jpsychires.2007.12.002, 18215400.
    • (2008) J Psychiatr Res , vol.42 , Issue.14 , pp. 1198-1202
    • Thomann, P.A.1    Schlafer, C.2    Seidl, U.3    Santos, V.D.4    Essig, M.5    Schroder, J.6
  • 69
    • 0030922502 scopus 로고    scopus 로고
    • Cerebellar pathology in sporadic and familial Alzheimer's disease including APP 717 (Val-->Ile) mutation cases: a morphometric investigation
    • 10.1016/S0022-510X(97)05399-9, 9171327
    • Fukutani Y, Cairns NJ, Rossor MN, Lantos PL. Cerebellar pathology in sporadic and familial Alzheimer's disease including APP 717 (Val-->Ile) mutation cases: a morphometric investigation. J Neurol Sci 1997, 149(2):177-184. 10.1016/S0022-510X(97)05399-9, 9171327.
    • (1997) J Neurol Sci , vol.149 , Issue.2 , pp. 177-184
    • Fukutani, Y.1    Cairns, N.J.2    Rossor, M.N.3    Lantos, P.L.4
  • 70
    • 0025210629 scopus 로고
    • Ubiquitin immunoelectron microscopy of dystrophic neurites in cerebellar senile plaques of Alzheimer's disease
    • 10.1007/BF00296107, 2158201
    • Dickson DW, Wertkin A, Mattiace LA, Fier E, Kress Y, Davies P, Yen SH. Ubiquitin immunoelectron microscopy of dystrophic neurites in cerebellar senile plaques of Alzheimer's disease. Acta Neuropathol 1990, 79(5):486-493. 10.1007/BF00296107, 2158201.
    • (1990) Acta Neuropathol , vol.79 , Issue.5 , pp. 486-493
    • Dickson, D.W.1    Wertkin, A.2    Mattiace, L.A.3    Fier, E.4    Kress, Y.5    Davies, P.6    Yen, S.H.7
  • 71
    • 67650142070 scopus 로고    scopus 로고
    • Dendritic pathology in Alzheimer's disease
    • 10.1016/j.jns.2009.02.370, 19296966
    • Baloyannis SJ. Dendritic pathology in Alzheimer's disease. J Neurol Sci 2009, 283(1-2):153-157. 10.1016/j.jns.2009.02.370, 19296966.
    • (2009) J Neurol Sci , vol.283 , Issue.1-2 , pp. 153-157
    • Baloyannis, S.J.1
  • 72
    • 0034157614 scopus 로고    scopus 로고
    • Synaptic alterations in the vestibulocerebellar system in Alzheimer's disease--a Golgi and electron microscope study
    • 10.1080/000164800750001026, 11603783
    • Baloyannis SJ, Manolidis SL, Manolidis LS. Synaptic alterations in the vestibulocerebellar system in Alzheimer's disease--a Golgi and electron microscope study. Acta Otolaryngol 2000, 120(2):247-250. 10.1080/000164800750001026, 11603783.
    • (2000) Acta Otolaryngol , vol.120 , Issue.2 , pp. 247-250
    • Baloyannis, S.J.1    Manolidis, S.L.2    Manolidis, L.S.3
  • 73
    • 34249820814 scopus 로고    scopus 로고
    • Pathological alterations of the climbing fibres of the cerebellum in vascular dementia: a Golgi and electron microscope study
    • 10.1016/j.jns.2007.03.003, 17448497
    • Baloyannis SJ. Pathological alterations of the climbing fibres of the cerebellum in vascular dementia: a Golgi and electron microscope study. J Neurol Sci 2007, 257(1-2):56-61. 10.1016/j.jns.2007.03.003, 17448497.
    • (2007) J Neurol Sci , vol.257 , Issue.1-2 , pp. 56-61
    • Baloyannis, S.J.1
  • 74
    • 0017729442 scopus 로고
    • Simultaneous occurrence of diabetes mellitus, diabetes insipidus, and optic atrophy in a brother and sister
    • Carson MJ, Slager UT, Steinberg RM. Simultaneous occurrence of diabetes mellitus, diabetes insipidus, and optic atrophy in a brother and sister. Am J Dis Child 1977, 131(12):1382-1385.
    • (1977) Am J Dis Child , vol.131 , Issue.12 , pp. 1382-1385
    • Carson, M.J.1    Slager, U.T.2    Steinberg, R.M.3
  • 75
    • 50849117830 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor resistance in alcoholic neurodegeneration
    • 10.1111/j.1530-0277.2008.00731.x, 18616667
    • de la Monte SM, Tong M, Cohen AC, Sheedy D, Harper C, Wands JR. Insulin and insulin-like growth factor resistance in alcoholic neurodegeneration. Alcohol Clin Exp Res 2008, 32(9):1630-1644. 10.1111/j.1530-0277.2008.00731.x, 18616667.
    • (2008) Alcohol Clin Exp Res , vol.32 , Issue.9 , pp. 1630-1644
    • de la Monte, S.M.1    Tong, M.2    Cohen, A.C.3    Sheedy, D.4    Harper, C.5    Wands, J.R.6
  • 76
    • 70349581633 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease
    • de la Monte SM. Insulin resistance and Alzheimer's disease. BMB Rep 2009, 42(8):475-481.
    • (2009) BMB Rep , vol.42 , Issue.8 , pp. 475-481
    • de la Monte, S.M.1
  • 77
    • 70449356621 scopus 로고    scopus 로고
    • GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling
    • 10.1093/hmg/ddp430, 19744960
    • Giovannone B, Tsiaras WG, de la Monte S, Klysik J, Lautier C, Karashchuk G, Goldwurm S, Smith RJ. GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling. Hum Mol Genet 2009, 18(23):4629-4639. 10.1093/hmg/ddp430, 19744960.
    • (2009) Hum Mol Genet , vol.18 , Issue.23 , pp. 4629-4639
    • Giovannone, B.1    Tsiaras, W.G.2    de la Monte, S.3    Klysik, J.4    Lautier, C.5    Karashchuk, G.6    Goldwurm, S.7    Smith, R.J.8
  • 78
    • 0034520593 scopus 로고    scopus 로고
    • Neurodegeneration is associated to changes in serum insulin-like growth factors
    • 10.1006/nbdi.2000.0311, 11114263
    • Busiguina S, Fernandez AM, Barrios V, Clark R, Tolbert DL, Berciano J, Torres-Aleman I. Neurodegeneration is associated to changes in serum insulin-like growth factors. Neurobiol Dis 2000, 7(6 Pt B):657-665. 10.1006/nbdi.2000.0311, 11114263.
    • (2000) Neurobiol Dis , vol.7 , Issue.6 PART B , pp. 657-665
    • Busiguina, S.1    Fernandez, A.M.2    Barrios, V.3    Clark, R.4    Tolbert, D.L.5    Berciano, J.6    Torres-Aleman, I.7
  • 79
    • 34548249096 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor resistance with neurodegeneration in an adult chronic ethanol exposure model
    • 10.1111/j.1530-0277.2007.00450.x, 17645580
    • Cohen AC, Tong M, Wands JR, de la Monte SM. Insulin and insulin-like growth factor resistance with neurodegeneration in an adult chronic ethanol exposure model. Alcohol Clin Exp Res 2007, 31(9):1558-1573. 10.1111/j.1530-0277.2007.00450.x, 17645580.
    • (2007) Alcohol Clin Exp Res , vol.31 , Issue.9 , pp. 1558-1573
    • Cohen, A.C.1    Tong, M.2    Wands, J.R.3    de la Monte, S.M.4
  • 80
    • 15244350991 scopus 로고    scopus 로고
    • Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease
    • de la Monte SM, Wands JR. Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease. J Alzheimers Dis 2005, 7(1):45-61.
    • (2005) J Alzheimers Dis , vol.7 , Issue.1 , pp. 45-61
    • de la Monte, S.M.1    Wands, J.R.2
  • 81
    • 68949089312 scopus 로고    scopus 로고
    • Alzheimer's Disease is Type 3 Diabetes: Evidence Reviewed
    • de la Monte SM, Wands JR. Alzheimer's Disease is Type 3 Diabetes: Evidence Reviewed. J Diabetes Science Tech 2008, 2(6):1101-1113.
    • (2008) J Diabetes Science Tech , vol.2 , Issue.6 , pp. 1101-1113
    • de la Monte, S.M.1    Wands, J.R.2
  • 82
    • 0027310868 scopus 로고
    • The distribution of amyloid plaques in the cerebellum and brain stem in Down's syndrome and Alzheimer's disease: a light microscopical analysis
    • 10.1007/BF00230495, 8493862
    • Cole G, Neal JW, Singhrao SK, Jasani B, Newman GR. The distribution of amyloid plaques in the cerebellum and brain stem in Down's syndrome and Alzheimer's disease: a light microscopical analysis. Acta Neuropathol 1993, 85(5):542-552. 10.1007/BF00230495, 8493862.
    • (1993) Acta Neuropathol , vol.85 , Issue.5 , pp. 542-552
    • Cole, G.1    Neal, J.W.2    Singhrao, S.K.3    Jasani, B.4    Newman, G.R.5
  • 83
    • 67649723058 scopus 로고    scopus 로고
    • Mechanisms of ceramide-mediated neurodegeneration
    • Tong M, de la Monte SM. Mechanisms of ceramide-mediated neurodegeneration. J Alzheimers Dis 2009, 16(4):705-714.
    • (2009) J Alzheimers Dis , vol.16 , Issue.4 , pp. 705-714
    • Tong, M.1    de la Monte, S.M.2
  • 84
    • 0025801114 scopus 로고
    • Mechanisms of fat-related modulation of N-nitrosodiethylamine-induced tumors in rats: organ distribution, blood lipids, enzymes and pro-oxidant state
    • 10.1093/carcin/12.4.591, 1672840
    • Hietanen E, Bartsch H, Ahotupa M, Bereziat JC, Bussacchini-Griot V, Cabral JR, Camus AM, Laitinen M, Wild H. Mechanisms of fat-related modulation of N-nitrosodiethylamine-induced tumors in rats: organ distribution, blood lipids, enzymes and pro-oxidant state. Carcinogenesis 1991, 12(4):591-600. 10.1093/carcin/12.4.591, 1672840.
    • (1991) Carcinogenesis , vol.12 , Issue.4 , pp. 591-600
    • Hietanen, E.1    Bartsch, H.2    Ahotupa, M.3    Bereziat, J.C.4    Bussacchini-Griot, V.5    Cabral, J.R.6    Camus, A.M.7    Laitinen, M.8    Wild, H.9
  • 85
    • 1442357755 scopus 로고    scopus 로고
    • Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development of Alzheimer's disease
    • 10.1042/BST0320144, 14748735
    • Alessenko AV, Bugrova AE, Dudnik LB. Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development of Alzheimer's disease. Biochem Soc Trans 2004, 32(Pt 1):144-146. 10.1042/BST0320144, 14748735.
    • (2004) Biochem Soc Trans , vol.32 , Issue.PART 1 , pp. 144-146
    • Alessenko, A.V.1    Bugrova, A.E.2    Dudnik, L.B.3
  • 86
    • 41949140023 scopus 로고    scopus 로고
    • Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
    • 10.1074/jbc.M707386200, 18165233
    • Laviad EL, Albee L, Pankova-Kholmyansky I, Epstein S, Park H, Merrill AH, Futerman AH. Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J Biol Chem 2008, 283(9):5677-5684. 10.1074/jbc.M707386200, 18165233.
    • (2008) J Biol Chem , vol.283 , Issue.9 , pp. 5677-5684
    • Laviad, E.L.1    Albee, L.2    Pankova-Kholmyansky, I.3    Epstein, S.4    Park, H.5    Merrill, A.H.6    Futerman, A.H.7
  • 87
    • 46649108016 scopus 로고    scopus 로고
    • Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1
    • 10.1074/jbc.M709950200, 2376236, 18359942
    • Shah C, Yang G, Lee I, Bielawski J, Hannun YA, Samad F. Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1. J Biol Chem 2008, 283(20):13538-13548. 10.1074/jbc.M709950200, 2376236, 18359942.
    • (2008) J Biol Chem , vol.283 , Issue.20 , pp. 13538-13548
    • Shah, C.1    Yang, G.2    Lee, I.3    Bielawski, J.4    Hannun, Y.A.5    Samad, F.6
  • 88
    • 31644443192 scopus 로고    scopus 로고
    • Ceramides in insulin resistance and lipotoxicity
    • 10.1016/j.plipres.2005.11.002, 16445986
    • Summers SA. Ceramides in insulin resistance and lipotoxicity. Prog Lipid Res 2006, 45(1):42-72. 10.1016/j.plipres.2005.11.002, 16445986.
    • (2006) Prog Lipid Res , vol.45 , Issue.1 , pp. 42-72
    • Summers, S.A.1
  • 89
    • 58149308844 scopus 로고    scopus 로고
    • Altered Lipid Metabolism in Brain Injury and Disorders
    • nihpa41041
    • Adibhatla RM, Hatcher JF. Altered Lipid Metabolism in Brain Injury and Disorders. Subcell Biochem 2008, 48. nihpa41041.
    • (2008) Subcell Biochem , vol.48
    • Adibhatla, R.M.1    Hatcher, J.F.2
  • 90
    • 33947577504 scopus 로고    scopus 로고
    • Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?
    • 10.1007/s11064-007-9297-x, 17342407
    • Katsel P, Li C, Haroutunian V. Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?. Neurochem Res 2007, 32(4-5):845-856. 10.1007/s11064-007-9297-x, 17342407.
    • (2007) Neurochem Res , vol.32 , Issue.4-5 , pp. 845-856
    • Katsel, P.1    Li, C.2    Haroutunian, V.3
  • 91
    • 0034704409 scopus 로고    scopus 로고
    • Lethal forebrain ischemia stimulates sphingomyelin hydrolysis and ceramide generation in the gerbil hippocampus
    • 10.1016/S0304-3940(00)01655-4, 11108988
    • Nakane M, Kubota M, Nakagomi T, Tamura A, Hisaki H, Shimasaki H, Ueta N. Lethal forebrain ischemia stimulates sphingomyelin hydrolysis and ceramide generation in the gerbil hippocampus. Neurosci Lett 2000, 296(2-3):89-92. 10.1016/S0304-3940(00)01655-4, 11108988.
    • (2000) Neurosci Lett , vol.296 , Issue.2-3 , pp. 89-92
    • Nakane, M.1    Kubota, M.2    Nakagomi, T.3    Tamura, A.4    Hisaki, H.5    Shimasaki, H.6    Ueta, N.7
  • 92
    • 0018874008 scopus 로고
    • Evidence for multiple causality in the development of diabetic hypertriglyceridaemia
    • 10.1007/BF00251016, 6998805
    • Weiland D, Mondon CE, Reaven GM. Evidence for multiple causality in the development of diabetic hypertriglyceridaemia. Diabetologia 1980, 18(4):335-340. 10.1007/BF00251016, 6998805.
    • (1980) Diabetologia , vol.18 , Issue.4 , pp. 335-340
    • Weiland, D.1    Mondon, C.E.2    Reaven, G.M.3
  • 93
    • 0019810501 scopus 로고
    • Dose response studies of carcinogenesis in rats by nitrosodiethylamine
    • Lijinsky W, Reuber MD, Riggs CW. Dose response studies of carcinogenesis in rats by nitrosodiethylamine. Cancer Res 1981, 41(12 Pt 1):4997-5003.
    • (1981) Cancer Res , vol.41 , Issue.12 PART 1 , pp. 4997-5003
    • Lijinsky, W.1    Reuber, M.D.2    Riggs, C.W.3
  • 94
    • 0019436453 scopus 로고
    • Induction of carcinogenesis in Fischer rats by methylalkylnitrosamines
    • Lijinsky W, Saavedra JE, Reuber MD. Induction of carcinogenesis in Fischer rats by methylalkylnitrosamines. Cancer Res 1981, 41(4):1288-1292.
    • (1981) Cancer Res , vol.41 , Issue.4 , pp. 1288-1292
    • Lijinsky, W.1    Saavedra, J.E.2    Reuber, M.D.3
  • 95
    • 26044457028 scopus 로고    scopus 로고
    • Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver
    • 10.1016/j.cbi.2005.08.001, 16144695
    • Bansal AK, Bansal M, Soni G, Bhatnagar D. Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver. Chem Biol Interact 2005, 156(2-3):101-111. 10.1016/j.cbi.2005.08.001, 16144695.
    • (2005) Chem Biol Interact , vol.156 , Issue.2-3 , pp. 101-111
    • Bansal, A.K.1    Bansal, M.2    Soni, G.3    Bhatnagar, D.4
  • 96
    • 0014945972 scopus 로고
    • Diethylnitrosamine oncogenesis in RF mice as influenced by variations in cumulative dose
    • 10.1002/ijc.2910050116, 5414737
    • Clapp NK, Craig AW, Toya RE. Diethylnitrosamine oncogenesis in RF mice as influenced by variations in cumulative dose. Int J Cancer 1970, 5(1):119-123. 10.1002/ijc.2910050116, 5414737.
    • (1970) Int J Cancer , vol.5 , Issue.1 , pp. 119-123
    • Clapp, N.K.1    Craig, A.W.2    Toya, R.E.3
  • 97
    • 0029884053 scopus 로고    scopus 로고
    • Age, education, and changes in the Mini-Mental State Exam scores of older women: findings from the Nun Study
    • Butler SM, Ashford JW, Snowdon DA. Age, education, and changes in the Mini-Mental State Exam scores of older women: findings from the Nun Study. J Am Geriatr Soc 1996, 44(6):675-681.
    • (1996) J Am Geriatr Soc , vol.44 , Issue.6 , pp. 675-681
    • Butler, S.M.1    Ashford, J.W.2    Snowdon, D.A.3
  • 98
    • 0030066467 scopus 로고    scopus 로고
    • Linguistic ability in early life and cognitive function and Alzheimer's disease in late life. Findings from the Nun Study
    • 10.1001/jama.275.7.528, 8606473
    • Snowdon DA, Kemper SJ, Mortimer JA, Greiner LH, Wekstein DR, Markesbery WR. Linguistic ability in early life and cognitive function and Alzheimer's disease in late life. Findings from the Nun Study. JAMA 1996, 275(7):528-532. 10.1001/jama.275.7.528, 8606473.
    • (1996) JAMA , vol.275 , Issue.7 , pp. 528-532
    • Snowdon, D.A.1    Kemper, S.J.2    Mortimer, J.A.3    Greiner, L.H.4    Wekstein, D.R.5    Markesbery, W.R.6
  • 100
    • 0028143405 scopus 로고
    • Pancreatic islet hypertrophy in spontaneous maturity onset obese-diabetic CBA/Ca mice
    • 10.1016/0020-711X(94)90099-X, 7851633
    • Figueroa CD, Taberner PV. Pancreatic islet hypertrophy in spontaneous maturity onset obese-diabetic CBA/Ca mice. Int J Biochem 1994, 26(10-11):1299-1303. 10.1016/0020-711X(94)90099-X, 7851633.
    • (1994) Int J Biochem , vol.26 , Issue.10-11 , pp. 1299-1303
    • Figueroa, C.D.1    Taberner, P.V.2
  • 101
    • 0033591017 scopus 로고    scopus 로고
    • Cholinergic markers in elderly patients with early signs of Alzheimer disease
    • 10.1001/jama.281.15.1401, 10217056
    • Davis KL, Mohs RC, Marin D, Purohit DP, Perl DP, Lantz M, Austin G, Haroutunian V. Cholinergic markers in elderly patients with early signs of Alzheimer disease. JAMA 1999, 281(15):1401-1406. 10.1001/jama.281.15.1401, 10217056.
    • (1999) JAMA , vol.281 , Issue.15 , pp. 1401-1406
    • Davis, K.L.1    Mohs, R.C.2    Marin, D.3    Purohit, D.P.4    Perl, D.P.5    Lantz, M.6    Austin, G.7    Haroutunian, V.8
  • 102
    • 0027363742 scopus 로고
    • Role of forebrain cholinergic systems in learning and memory: relevance to the cognitive deficits of aging and Alzheimer's dementia
    • full_text, 8248529
    • Dunnett SB, Fibiger HC. Role of forebrain cholinergic systems in learning and memory: relevance to the cognitive deficits of aging and Alzheimer's dementia. Prog Brain Res 1993, 98:413-420. full_text, 8248529.
    • (1993) Prog Brain Res , vol.98 , pp. 413-420
    • Dunnett, S.B.1    Fibiger, H.C.2
  • 104
    • 65549103889 scopus 로고    scopus 로고
    • Brain insulin-like growth factor and neurotrophin resistance in Parkinson's disease and dementia with Lewy bodies: potential role of manganese neurotoxicity
    • Tong M, Dong M, de la Monte SM. Brain insulin-like growth factor and neurotrophin resistance in Parkinson's disease and dementia with Lewy bodies: potential role of manganese neurotoxicity. J Alzheimers Dis 2009, 16(3):585-599.
    • (2009) J Alzheimers Dis , vol.16 , Issue.3 , pp. 585-599
    • Tong, M.1    Dong, M.2    de la Monte, S.M.3
  • 105
    • 0029950593 scopus 로고    scopus 로고
    • Nitrosamines, alcohol, and gastrointestinal tract cancer: recent epidemiology and experimentation
    • Chhabra SK, Souliotis VL, Kyrtopoulos SA, Anderson LM. Nitrosamines, alcohol, and gastrointestinal tract cancer: recent epidemiology and experimentation. In Vivo 1996, 10(3):265-284.
    • (1996) In Vivo , vol.10 , Issue.3 , pp. 265-284
    • Chhabra, S.K.1    Souliotis, V.L.2    Kyrtopoulos, S.A.3    Anderson, L.M.4
  • 106
    • 34548629011 scopus 로고    scopus 로고
    • DNA damage measured by comet assay and 8-OH-dG formation related to blood chemical analyses in aged rats
    • 10.2131/jts.32.249, 17785942
    • Hashimoto K, Takasaki W, Sato I, Tsuda S. DNA damage measured by comet assay and 8-OH-dG formation related to blood chemical analyses in aged rats. J Toxicol Sci 2007, 32(3):249-259. 10.2131/jts.32.249, 17785942.
    • (2007) J Toxicol Sci , vol.32 , Issue.3 , pp. 249-259
    • Hashimoto, K.1    Takasaki, W.2    Sato, I.3    Tsuda, S.4
  • 107
    • 39349083784 scopus 로고    scopus 로고
    • Haemoglobin adducts as biomarkers of exposure to tobacco-related nitrosamines
    • 10.1080/13547500701470561, 18270868
    • Myers SR, Ali MY. Haemoglobin adducts as biomarkers of exposure to tobacco-related nitrosamines. Biomarkers 2008, 13(2):145-159. 10.1080/13547500701470561, 18270868.
    • (2008) Biomarkers , vol.13 , Issue.2 , pp. 145-159
    • Myers, S.R.1    Ali, M.Y.2
  • 108
    • 84860493578 scopus 로고    scopus 로고
    • Lipid mediators of insulin resistance
    • 10.1111/j.1753-4887.2007.tb00327.x, 17605313
    • Holland WL, Knotts TA, Chavez JA, Wang LP, Hoehn KL, Summers SA. Lipid mediators of insulin resistance. Nutr Rev 2007, 65(6 Pt 2):S39-46. 10.1111/j.1753-4887.2007.tb00327.x, 17605313.
    • (2007) Nutr Rev , vol.65 , Issue.6 PART 2
    • Holland, W.L.1    Knotts, T.A.2    Chavez, J.A.3    Wang, L.P.4    Hoehn, K.L.5    Summers, S.A.6
  • 109
    • 43249083481 scopus 로고    scopus 로고
    • Free fatty acids and skeletal muscle insulin resistance
    • 10.1097/01.mol.0000319118.44995.9a, 18460913
    • Kraegen EW, Cooney GJ. Free fatty acids and skeletal muscle insulin resistance. Curr Opin Lipidol 2008, 19(3):235-241. 10.1097/01.mol.0000319118.44995.9a, 18460913.
    • (2008) Curr Opin Lipidol , vol.19 , Issue.3 , pp. 235-241
    • Kraegen, E.W.1    Cooney, G.J.2
  • 110
    • 38949163057 scopus 로고    scopus 로고
    • Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes
    • 10.1002/glia.20626, 18205190
    • Wang G, Silva J, Dasgupta S, Bieberich E. Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes. Glia 2008, 56(4):449-456. 10.1002/glia.20626, 18205190.
    • (2008) Glia , vol.56 , Issue.4 , pp. 449-456
    • Wang, G.1    Silva, J.2    Dasgupta, S.3    Bieberich, E.4
  • 111
    • 1242338183 scopus 로고    scopus 로고
    • Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease
    • 10.1073/pnas.0305799101, 357053, 14970312
    • Cutler RG, Kelly J, Storie K, Pedersen WA, Tammara A, Hatanpaa K, Troncoso JC, Mattson MP. Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease. Proc Natl Acad Sci USA 2004, 101(7):2070-2075. 10.1073/pnas.0305799101, 357053, 14970312.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.7 , pp. 2070-2075
    • Cutler, R.G.1    Kelly, J.2    Storie, K.3    Pedersen, W.A.4    Tammara, A.5    Hatanpaa, K.6    Troncoso, J.C.7    Mattson, M.P.8
  • 112
    • 0036677303 scopus 로고    scopus 로고
    • Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis
    • 10.1046/j.1471-4159.2002.00997.x, 12358786
    • Han X, D MH, McKeel DW, Kelley J, Morris JC. Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis. J Neurochem 2002, 82(4):809-818. 10.1046/j.1471-4159.2002.00997.x, 12358786.
    • (2002) J Neurochem , vol.82 , Issue.4 , pp. 809-818
    • Han, X.1    D, M.H.2    McKeel, D.W.3    Kelley, J.4    Morris, J.C.5
  • 113
    • 0031054724 scopus 로고    scopus 로고
    • Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease
    • 10.1016/S0165-0173(96)00014-8, 9063586
    • Mattson MP, Barger SW, Furukawa K, Bruce AJ, Wyss-Coray T, Mark RJ, Mucke L. Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease. Brain Res Brain Res Rev 1997, 23(1-2):47-61. 10.1016/S0165-0173(96)00014-8, 9063586.
    • (1997) Brain Res Brain Res Rev , vol.23 , Issue.1-2 , pp. 47-61
    • Mattson, M.P.1    Barger, S.W.2    Furukawa, K.3    Bruce, A.J.4    Wyss-Coray, T.5    Mark, R.J.6    Mucke, L.7
  • 114
    • 0030478489 scopus 로고    scopus 로고
    • Membrane components separate early-onset Alzheimer's disease from senile dementia of the Alzheimer type
    • 10.1017/S1041610296002736, 9116173
    • Gottfries CG, Karlsson I, Svennerholm L. Membrane components separate early-onset Alzheimer's disease from senile dementia of the Alzheimer type. Int Psychogeriatr 1996, 8(3):365-372. 10.1017/S1041610296002736, 9116173.
    • (1996) Int Psychogeriatr , vol.8 , Issue.3 , pp. 365-372
    • Gottfries, C.G.1    Karlsson, I.2    Svennerholm, L.3
  • 116
    • 0017745860 scopus 로고
    • Liposolubility as an aspect of nitrosamine carcinogenicity: quantitative correlations and qualitative observations
    • 10.1016/0009-2797(77)90026-6, 589698
    • Singer GM, Taylor HW, Lijinsky W. Liposolubility as an aspect of nitrosamine carcinogenicity: quantitative correlations and qualitative observations. Chem Biol Interact 1977, 19(2):133-142. 10.1016/0009-2797(77)90026-6, 589698.
    • (1977) Chem Biol Interact , vol.19 , Issue.2 , pp. 133-142
    • Singer, G.M.1    Taylor, H.W.2    Lijinsky, W.3
  • 117
    • 0025078160 scopus 로고
    • N-nitrosamines in the stomach with special reference to in vitro formation, and kinetics after intragastric or intravenous administration in rats
    • Hinuma K, Matsuda J, Tanida N, Hori S, Tamura K, Ohno T, Kano M, Shimoyama T. N-nitrosamines in the stomach with special reference to in vitro formation, and kinetics after intragastric or intravenous administration in rats. Gastroenterol Jpn 1990, 25(4):417-424.
    • (1990) Gastroenterol Jpn , vol.25 , Issue.4 , pp. 417-424
    • Hinuma, K.1    Matsuda, J.2    Tanida, N.3    Hori, S.4    Tamura, K.5    Ohno, T.6    Kano, M.7    Shimoyama, T.8


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