Presenilin regulates insulin signaling via a γ-secretase-independent mechanism

Journal of Biological Chemistry

Volumn 286, Issue 28, 2011, Pages 25309-25316

  Maesako, Masato ^a   Uemura, Kengo ^a   Kuzuya, Akira ^a   Sasaki, Kazuki ^a   Asada, Megumi ^a   Watanabe, Kiwamu ^a   Ando, Koichi ^a   Kubota, Masakazu ^a   Kihara, Takeshi ^a   Kinoshita, Ayae ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEINS; CATENIN SIGNALING; CELL SURFACE RECEPTORS; DOWN-REGULATION; EXPRESSION LEVELS; INSULIN RECEPTORS; INSULIN SIGNALING; INTRACELLULAR CA; PRESENILINS; SECRETASE COMPLEX; SECRETASES; TRANS-MEMBRANE PROTEINS;

CELL MEMBRANES; PROTEINS; SIGNALING;

INSULIN;

BETA CATENIN; CALCIUM ION; GAMMA SECRETASE; INSULIN; INSULIN RECEPTOR; PROTEIN KINASE B; WNT PROTEIN;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FIBROBLAST; GENE; INSULIN SIGNALING; MOUSE; NONHUMAN; PRESENILIN GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BETA CATENIN; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; GENE EXPRESSION REGULATION; INSULIN; MICE; MICE, KNOCKOUT; PRESENILINS; RECEPTOR, INSULIN; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 79960119114     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.248922     Document Type: Article

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