Chronic gestational exposure to ethanol impairs insulin-stimulated survival and mitochondrial function in cerebellar neurons

Cellular and Molecular Life Sciences

Volumn 59, Issue 5, 2002, Pages 882-893

  De La Monte, S M ^a   Wands, J R ^a  

^a RHODE ISLAND HOSPITAL   (United States)

Author keywords

Central nervous system; Fetal alcohol syndrome; Fetal ethanol effects; Insulin; Mitochondria; Neuronal apoptosis; Signal transduction

Indexed keywords

ALCOHOL; BAD GENE; CALCEIN; DIHYDROROSAMINE; FAS ANTIGEN; FAS LIGAND; GENE PRODUCT; INSULIN; PROTEIN GSKBETA; PROTEIN KINASE B; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; CELL MEMBRANE; CELL VIABILITY; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CONTROLLED STUDY; FEMALE; FETAL ALCOHOL SYNDROME; FLUORESCENCE; GENE EXPRESSION; GESTATIONAL AGE; HEMISPHERE; INSULIN RELEASE; MITOCHONDRION; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PHOSPHORYLATION; PRENATAL EXPOSURE; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SURVIVAL;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; DISEASE MODELS, ANIMAL; ETHANOL; FEMALE; FETAL ALCOHOL SYNDROME; FETUS; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASE 3; INSULIN; MITOCHONDRIA; NEURONS; PREGNANCY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, LONG-EVANS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0036282840     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-002-8475-x     Document Type: Article

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