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Volumn 199, Issue , 2016, Pages 144-160

Cholesterol oxidation products and their biological importance

Author keywords

Biological membranes; Biophysical properties; Cholesterol; Oxidation; Oxidative stress; Oxysterols; Reactive oxygen species

Indexed keywords

CHOLESTEROL; DETERGENT; OXYSTEROL; LIPID BILAYER;

EID: 84959894259     PISSN: 00093084     EISSN: 18732941     Source Type: Journal    
DOI: 10.1016/j.chemphyslip.2016.03.001     Document Type: Article
Times cited : (145)

References (279)
  • 3
    • 33646227665 scopus 로고    scopus 로고
    • Detergent solubilization of phosphatidylcholine bilayers in the fluid state: influence of the acyl chain structure
    • Ahyayauch, H., Larijani, B., Alonso, A., Goni, F.M., Detergent solubilization of phosphatidylcholine bilayers in the fluid state: influence of the acyl chain structure. Biochim. Et Biophys. Acta-Biomembr. 1758 (2006), 190–196.
    • (2006) Biochim. Et Biophys. Acta-Biomembr. , vol.1758 , pp. 190-196
    • Ahyayauch, H.1    Larijani, B.2    Alonso, A.3    Goni, F.M.4
  • 9
  • 10
    • 40149102522 scopus 로고    scopus 로고
    • Interaction of 7-ketocholesterol with two major components of the inner leaflet of the plasma membrane: phosphatidylethanolamine and phosphatidylserine
    • Bach, D., Epand, R.F., Epand, R.M., Wachtel, E., Interaction of 7-ketocholesterol with two major components of the inner leaflet of the plasma membrane: phosphatidylethanolamine and phosphatidylserine. Biochemistry 47 (2008), 3004–3012.
    • (2008) Biochemistry , vol.47 , pp. 3004-3012
    • Bach, D.1    Epand, R.F.2    Epand, R.M.3    Wachtel, E.4
  • 11
    • 69849098845 scopus 로고    scopus 로고
    • The oxidized form of cholesterol 3 beta-hydroxy-5-oxo-5,6-secocholestan-6-al induces structural and thermotropic changes in phospholipid membranes
    • Bach, D., Epand, R.F., Epand, R.M., Miller, I.R., Wachtel, E., The oxidized form of cholesterol 3 beta-hydroxy-5-oxo-5,6-secocholestan-6-al induces structural and thermotropic changes in phospholipid membranes. Chem. Phys. Lipids 161 (2009), 95–102.
    • (2009) Chem. Phys. Lipids , vol.161 , pp. 95-102
    • Bach, D.1    Epand, R.F.2    Epand, R.M.3    Miller, I.R.4    Wachtel, E.5
  • 12
    • 80053217739 scopus 로고    scopus 로고
    • The oxysterol 3 beta-hydroxy-5-oxo-5,6-secocholestan-6-al changes the phase behavior and structure of phosphatidylethanolamine-phosphatidylcholine mixtures
    • Bach, D., Epand, R.F., Epand, R.M., Miller, I.R., Wachtel, E., The oxysterol 3 beta-hydroxy-5-oxo-5,6-secocholestan-6-al changes the phase behavior and structure of phosphatidylethanolamine-phosphatidylcholine mixtures. Chem. Phys. Lipids 164 (2011), 672–679.
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 672-679
    • Bach, D.1    Epand, R.F.2    Epand, R.M.3    Miller, I.R.4    Wachtel, E.5
  • 13
    • 84921417231 scopus 로고    scopus 로고
    • Modulation of the kinetics of 3 beta-hydroxy-5-oxo-5,6-secocholestan-6-al/phosphatidylethanolamine Schiff base formation by cholesterol and cholesterol crystallization
    • Bach, D., Wachtel, E., Miller, I.R., Modulation of the kinetics of 3 beta-hydroxy-5-oxo-5,6-secocholestan-6-al/phosphatidylethanolamine Schiff base formation by cholesterol and cholesterol crystallization. Chem. Phys. Lipids 186 (2015), 45–50.
    • (2015) Chem. Phys. Lipids , vol.186 , pp. 45-50
    • Bach, D.1    Wachtel, E.2    Miller, I.R.3
  • 14
    • 14744278787 scopus 로고    scopus 로고
    • Sterol structure determines the separation of phases and the curvature of the liquid-ordered phase in model membranes
    • Bacia, K., Schwille, P., Kurzchalia, T., Sterol structure determines the separation of phases and the curvature of the liquid-ordered phase in model membranes. Proc. Natl. Acad. Sci. U. S. A. 102 (2005), 3272–3277.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 3272-3277
    • Bacia, K.1    Schwille, P.2    Kurzchalia, T.3
  • 15
    • 24144500631 scopus 로고    scopus 로고
    • Sterol structure determines miscibility versus melting transitions in lipid vesicles
    • Beattie, M.E., Veatch, S.L., Stottrup, B.L., Keller, S.L., Sterol structure determines miscibility versus melting transitions in lipid vesicles. Biophys. J. 89 (2005), 1760–1768.
    • (2005) Biophys. J. , vol.89 , pp. 1760-1768
    • Beattie, M.E.1    Veatch, S.L.2    Stottrup, B.L.3    Keller, S.L.4
  • 17
    • 58149202333 scopus 로고    scopus 로고
    • Detailed molecular dynamics simulations of model biological membranes containing cholesterol
    • Berkowitz, M.L., Detailed molecular dynamics simulations of model biological membranes containing cholesterol. Biochim. Et Biophys. Acta-Biomembr. 1788 (2009), 86–96.
    • (2009) Biochim. Et Biophys. Acta-Biomembr. , vol.1788 , pp. 86-96
    • Berkowitz, M.L.1
  • 18
    • 4344631831 scopus 로고    scopus 로고
    • Involvement of a calcium-dependent dephosphorylation of BAD associated with the localization of Trpc-1 within lipid rafts in 7-ketocholesterol-induced THP-1 cell apoptosis
    • Berthier, A., Lemaire-Ewing, S., Prunet, C., Monier, S., Athias, A., Bessede, G., de Barros, J.P.P., Laubriet, A., Gambert, P., Lizard, G., Neel, D., Involvement of a calcium-dependent dephosphorylation of BAD associated with the localization of Trpc-1 within lipid rafts in 7-ketocholesterol-induced THP-1 cell apoptosis. Cell Death Differ. 11 (2004), 897–905.
    • (2004) Cell Death Differ. , vol.11 , pp. 897-905
    • Berthier, A.1    Lemaire-Ewing, S.2    Prunet, C.3    Monier, S.4    Athias, A.5    Bessede, G.6    de Barros, J.P.P.7    Laubriet, A.8    Gambert, P.9    Lizard, G.10    Neel, D.11
  • 19
  • 20
    • 33947706821 scopus 로고    scopus 로고
    • Rediscovery of cerebrosterol
    • Björkhem, I., Rediscovery of cerebrosterol. Lipids 42 (2007), 5–14.
    • (2007) Lipids , vol.42 , pp. 5-14
    • Björkhem, I.1
  • 22
    • 0035076216 scopus 로고    scopus 로고
    • Genes involved in initial steps of bile acid synthesis
    • Bjorkhem, I., Eggertsen, G., Genes involved in initial steps of bile acid synthesis. Curr. Opin. Lipidol. 12 (2001), 97–103.
    • (2001) Curr. Opin. Lipidol. , vol.12 , pp. 97-103
    • Bjorkhem, I.1    Eggertsen, G.2
  • 23
    • 0031848338 scopus 로고    scopus 로고
    • Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation
    • Bjorkhem, I., Lutjohann, D., Diczfalusy, U., Stahle, L., Ahlborg, G., Wahren, J., Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. J. Lipid Res. 39 (1998), 1594–1600.
    • (1998) J. Lipid Res. , vol.39 , pp. 1594-1600
    • Bjorkhem, I.1    Lutjohann, D.2    Diczfalusy, U.3    Stahle, L.4    Ahlborg, G.5    Wahren, J.6
  • 25
    • 84885120728 scopus 로고    scopus 로고
    • Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease
    • Bjorkhem, I., Lovgren-Sandblom, A., Leoni, V., Meaney, S., Brodin, L., Salveson, L., Winge, K., Palhagen, S., Svenningsson, P., Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease. Neurosci. Lett. 555 (2013), 102–105.
    • (2013) Neurosci. Lett. , vol.555 , pp. 102-105
    • Bjorkhem, I.1    Lovgren-Sandblom, A.2    Leoni, V.3    Meaney, S.4    Brodin, L.5    Salveson, L.6    Winge, K.7    Palhagen, S.8    Svenningsson, P.9
  • 26
    • 0036736781 scopus 로고    scopus 로고
    • Do oxysterols control cholesterol homeostasis?
    • Bjorkhem, I., Do oxysterols control cholesterol homeostasis?. J. Clin. Invest. 110 (2002), 725–730.
    • (2002) J. Clin. Invest. , vol.110 , pp. 725-730
    • Bjorkhem, I.1
  • 27
    • 33751096969 scopus 로고    scopus 로고
    • Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain
    • Bjorkhem, I., Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain. J. Intern. Med. 260 (2006), 493–508.
    • (2006) J. Intern. Med. , vol.260 , pp. 493-508
    • Bjorkhem, I.1
  • 30
    • 0022343965 scopus 로고
    • 25-Hydroxycholesterol-induced elevations in ca-45 uptake—permeability changes in P815-cells
    • Boissonneault, G.A., Heiniger, H.J., 25-Hydroxycholesterol-induced elevations in ca-45 uptake—permeability changes in P815-cells. J. Cell. Physiol. 125 (1985), 471–475.
    • (1985) J. Cell. Physiol. , vol.125 , pp. 471-475
    • Boissonneault, G.A.1    Heiniger, H.J.2
  • 31
    • 33646451063 scopus 로고    scopus 로고
    • Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization
    • Bosco, D.A., Fowler, D.M., Zhang, Q., Nieva, J., Powers, E.T., Wentworth, P. Jr., Lerner, R.A., Kelly, J.W., Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization. Nat. Chem. Biol. 2 (2006), 249–253.
    • (2006) Nat. Chem. Biol. , vol.2 , pp. 249-253
    • Bosco, D.A.1    Fowler, D.M.2    Zhang, Q.3    Nieva, J.4    Powers, E.T.5    Wentworth, P.6    Lerner, R.A.7    Kelly, J.W.8
  • 32
    • 53549117711 scopus 로고    scopus 로고
    • Cholesterol photosensitised oxidation of beef meat under standard and modified atmosphere at retail conditions
    • Boselli, E., Rodriguez-Estrada, M.T., Fedrizzi, G., Caboni, M.F., Cholesterol photosensitised oxidation of beef meat under standard and modified atmosphere at retail conditions. Meat Sci. 81 (2009), 224–229.
    • (2009) Meat Sci. , vol.81 , pp. 224-229
    • Boselli, E.1    Rodriguez-Estrada, M.T.2    Fedrizzi, G.3    Caboni, M.F.4
  • 34
    • 0024988421 scopus 로고
    • Simultaneous quantification of several cholesterol autoxidation and monohydroxylation products by isotope-dilution mass-spectrometry
    • Breuer, O., Bjorkhem, I., Simultaneous quantification of several cholesterol autoxidation and monohydroxylation products by isotope-dilution mass-spectrometry. Steroids 55 (1990), 185–192.
    • (1990) Steroids , vol.55 , pp. 185-192
    • Breuer, O.1    Bjorkhem, I.2
  • 35
    • 0028982224 scopus 로고
    • Use of an O-18(2) inhalation technique and mass isotopomer distribution analysis to study oxygenation of cholesterol in rat—evidence for in-vivo formation of 7-oxocholesterol, 7-beta-hydroxycholesterol, 24-hydroxycholesterol, and 24-hydroxycholesterol
    • Breuer, O., Bjorkhem, I., Use of an O-18(2) inhalation technique and mass isotopomer distribution analysis to study oxygenation of cholesterol in rat—evidence for in-vivo formation of 7-oxocholesterol, 7-beta-hydroxycholesterol, 24-hydroxycholesterol, and 24-hydroxycholesterol. J. Biol. Chem. 270 (1995), 20278–20284.
    • (1995) J. Biol. Chem. , vol.270 , pp. 20278-20284
    • Breuer, O.1    Bjorkhem, I.2
  • 36
    • 0028971227 scopus 로고
    • Identification and quantitation of cholest-5-ene-3-beta,4-beta-diol in rat-liver and human plasma
    • Breuer, O., Identification and quantitation of cholest-5-ene-3-beta,4-beta-diol in rat-liver and human plasma. J. Lipid Res. 36 (1995), 2275–2281.
    • (1995) J. Lipid Res. , vol.36 , pp. 2275-2281
    • Breuer, O.1
  • 37
    • 0032890337 scopus 로고    scopus 로고
    • Oxysterols and atherosclerosis
    • Brown, A.J., Jessup, W., Oxysterols and atherosclerosis. Atherosclerosis 142 (1999), 1–28.
    • (1999) Atherosclerosis , vol.142 , pp. 1-28
    • Brown, A.J.1    Jessup, W.2
  • 38
    • 67349268463 scopus 로고    scopus 로고
    • Oxysterols: sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis
    • Brown, A.J., Jessup, W., Oxysterols: sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis. Mol. Aspects Med. 30 (2009), 111–122.
    • (2009) Mol. Aspects Med. , vol.30 , pp. 111-122
    • Brown, A.J.1    Jessup, W.2
  • 39
    • 0031558768 scopus 로고    scopus 로고
    • Structure of detergent-resistant membrane domains: does phase separation occur in biological membranes?
    • Brown, D.A., London, E., Structure of detergent-resistant membrane domains: does phase separation occur in biological membranes?. Biochem. Biophys. Res. Commun. 240 (1997), 1–7.
    • (1997) Biochem. Biophys. Res. Commun. , vol.240 , pp. 1-7
    • Brown, D.A.1    London, E.2
  • 40
    • 0029872744 scopus 로고    scopus 로고
    • Free and esterified oxysterol: formation during copper-oxidation of low density lipoprotein and uptake by macrophages
    • Brown, A.J., Dean, R.T., Jessup, W., Free and esterified oxysterol: formation during copper-oxidation of low density lipoprotein and uptake by macrophages. J. Lipid Res. 37 (1996), 320–335.
    • (1996) J. Lipid Res. , vol.37 , pp. 320-335
    • Brown, A.J.1    Dean, R.T.2    Jessup, W.3
  • 41
    • 0030820068 scopus 로고    scopus 로고
    • 7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque
    • Brown, A.J., Leong, S.L., Dean, R.T., Jessup, W., 7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque. J. Lipid Res. 38 (1997), 1730–1745.
    • (1997) J. Lipid Res. , vol.38 , pp. 1730-1745
    • Brown, A.J.1    Leong, S.L.2    Dean, R.T.3    Jessup, W.4
  • 42
    • 0033995604 scopus 로고    scopus 로고
    • Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells: accumulation of oxidized esters in lysosomes
    • Brown, A.J., Mander, E.L., Gelissen, I.C., Kritharides, L., Dean, R.T., Jessup, W., Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells: accumulation of oxidized esters in lysosomes. J. Lipid Res. 41 (2000), 226–236.
    • (2000) J. Lipid Res. , vol.41 , pp. 226-236
    • Brown, A.J.1    Mander, E.L.2    Gelissen, I.C.3    Kritharides, L.4    Dean, R.T.5    Jessup, W.6
  • 43
    • 0034623160 scopus 로고    scopus 로고
    • Sterol 27-hydroxylase acts on 7-Ketocholesterol in human atherosclerotic lesions and macrophages in culture
    • Brown, A.J., Watts, G.F., Burnett, J.R., Dean, R.T., Jessup, W., Sterol 27-hydroxylase acts on 7-Ketocholesterol in human atherosclerotic lesions and macrophages in culture. J. Biol. Chem. 275 (2000), 27627–27633.
    • (2000) J. Biol. Chem. , vol.275 , pp. 27627-27633
    • Brown, A.J.1    Watts, G.F.2    Burnett, J.R.3    Dean, R.T.4    Jessup, W.5
  • 47
    • 0036774743 scopus 로고    scopus 로고
    • Good COP, Bad COP: an unsolved murder. Are dietary cholesterol oxidation products guilty of atherogenicity?
    • Carpenter, K.L.H., Good COP, Bad COP: an unsolved murder. Are dietary cholesterol oxidation products guilty of atherogenicity?. Br. J. Nutr. 88 (2002), 335–338.
    • (2002) Br. J. Nutr. , vol.88 , pp. 335-338
    • Carpenter, K.L.H.1
  • 48
    • 84920284167 scopus 로고    scopus 로고
    • Oxysterols regulate encephalitogenic CD4(+) T cell trafficking during central nervous system autoimmunity
    • Chalmin, F., Rochemont, V., Lippens, C., Clottu, A., Sailer, A.W., Merkler, D., Hugues, S., Pot, C., Oxysterols regulate encephalitogenic CD4(+) T cell trafficking during central nervous system autoimmunity. J. Autoimmun. 56 (2015), 45–55.
    • (2015) J. Autoimmun. , vol.56 , pp. 45-55
    • Chalmin, F.1    Rochemont, V.2    Lippens, C.3    Clottu, A.4    Sailer, A.W.5    Merkler, D.6    Hugues, S.7    Pot, C.8
  • 49
    • 0035796796 scopus 로고    scopus 로고
    • The interactions of amphotericin B with various sterols in relation to its possible use in anticancer therapy
    • Charbonneau, C., Fournier, I., Dufresne, S., Barwicz, J., Tancrede, P., The interactions of amphotericin B with various sterols in relation to its possible use in anticancer therapy. Biophys. Chem. 91 (2001), 125–133.
    • (2001) Biophys. Chem. , vol.91 , pp. 125-133
    • Charbonneau, C.1    Fournier, I.2    Dufresne, S.3    Barwicz, J.4    Tancrede, P.5
  • 50
    • 84933516714 scopus 로고    scopus 로고
    • Is 25-hydroxycholesterol the interplay of statins and inflammation?
    • Chen, J.H., Peng, D.Q., Is 25-hydroxycholesterol the interplay of statins and inflammation?. Int. J. Cardiol. 184 (2015), 255–256.
    • (2015) Int. J. Cardiol. , vol.184 , pp. 255-256
    • Chen, J.H.1    Peng, D.Q.2
  • 51
    • 0036237015 scopus 로고    scopus 로고
    • 25-Hydroxycholesterol is produced by testicular macrophages during the early postnatal period and influences differentiation of leydig cells in vitro
    • Chen, J.J., Lukyanenko, Y., Hutson, J.C., 25-Hydroxycholesterol is produced by testicular macrophages during the early postnatal period and influences differentiation of leydig cells in vitro. Biol. Reprod. 66 (2002), 1336–1341.
    • (2002) Biol. Reprod. , vol.66 , pp. 1336-1341
    • Chen, J.J.1    Lukyanenko, Y.2    Hutson, J.C.3
  • 52
    • 33845587711 scopus 로고    scopus 로고
    • Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice
    • Chen, W., Chen, G., Head, D.L., Mangelsdorf, D.J., Russell, D.W., Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. Cell Metab. 5 (2007), 73–79.
    • (2007) Cell Metab. , vol.5 , pp. 73-79
    • Chen, W.1    Chen, G.2    Head, D.L.3    Mangelsdorf, D.J.4    Russell, D.W.5
  • 53
    • 1242269851 scopus 로고    scopus 로고
    • Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms
    • Chiang, J.Y.L., Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms. J. Hepatol. 40 (2004), 539–551.
    • (2004) J. Hepatol. , vol.40 , pp. 539-551
    • Chiang, J.Y.L.1
  • 54
    • 0034659148 scopus 로고    scopus 로고
    • The oxidative modification hypothesis of atherogenesis: an overview
    • Chisolm, G.M., Steinberg, D., The oxidative modification hypothesis of atherogenesis: an overview. Free Radic. Biol. Med. 28 (2000), 1815–1826.
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 1815-1826
    • Chisolm, G.M.1    Steinberg, D.2
  • 55
    • 84930902202 scopus 로고    scopus 로고
    • Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol
    • Civra, A., Cagno, V., Donalisio, M., Biasi, F., Leonarduzzi, G., Poli, G., Lembo, D., Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol. Sci. Rep., 4, 2014, 7487.
    • (2014) Sci. Rep. , vol.4 , pp. 7487
    • Civra, A.1    Cagno, V.2    Donalisio, M.3    Biasi, F.4    Leonarduzzi, G.5    Poli, G.6    Lembo, D.7
  • 56
    • 0033953170 scopus 로고    scopus 로고
    • GSH extrusion and the mitochondrial pathway of apoptotic signalling
    • Coppola, S., Ghibelli, L., GSH extrusion and the mitochondrial pathway of apoptotic signalling. Biochem. Soc. Trans. 28 (2000), 56–61.
    • (2000) Biochem. Soc. Trans. , vol.28 , pp. 56-61
    • Coppola, S.1    Ghibelli, L.2
  • 57
    • 80855133525 scopus 로고    scopus 로고
    • Cell membranes: the lipid perspective
    • Coskun, U., Simons, K., Cell membranes: the lipid perspective. Structure 19 (2011), 1543–1548.
    • (2011) Structure , vol.19 , pp. 1543-1548
    • Coskun, U.1    Simons, K.2
  • 59
    • 84922393584 scopus 로고    scopus 로고
    • 25-Hydroxycholesterols in innate and adaptive immunity
    • Cyster, J.G., Dang, E.V., Reboldi, A., Yi, T., 25-Hydroxycholesterols in innate and adaptive immunity. Nat. Rev. Immunol. 14 (2014), 731–743.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 731-743
    • Cyster, J.G.1    Dang, E.V.2    Reboldi, A.3    Yi, T.4
  • 60
    • 77956494238 scopus 로고    scopus 로고
    • The oxysterol 27-hydroxycholesterol increases beta-amyloid and oxidative stress in retinal pigment epithelial cells
    • Dasari, B., Prasanthi, J.R.P., Marwarha, G., Singh, B.B., Ghribi, O., The oxysterol 27-hydroxycholesterol increases beta-amyloid and oxidative stress in retinal pigment epithelial cells. BMC Ophthalmol., 10, 2010.
    • (2010) BMC Ophthalmol. , vol.10
    • Dasari, B.1    Prasanthi, J.R.P.2    Marwarha, G.3    Singh, B.B.4    Ghribi, O.5
  • 62
    • 0028816863 scopus 로고
    • Determination of cholesterol oxidation-products in human plasma by isotope-dilution mass-spectrometry
    • Dzeletovic, S., Breuer, O., Lund, E., Diczfalusy, U., Determination of cholesterol oxidation-products in human plasma by isotope-dilution mass-spectrometry. Anal. Biochem. 225 (1995), 73–80.
    • (1995) Anal. Biochem. , vol.225 , pp. 73-80
    • Dzeletovic, S.1    Breuer, O.2    Lund, E.3    Diczfalusy, U.4
  • 63
    • 10044271037 scopus 로고    scopus 로고
    • SREBP transcription factors: master regulators of lipid homeostasis
    • Eberlé, D., Hegarty, B., Bossard, P., Ferré, P., Foufelle, F., SREBP transcription factors: master regulators of lipid homeostasis. Biochimie 86 (2004), 839–848.
    • (2004) Biochimie , vol.86 , pp. 839-848
    • Eberlé, D.1    Hegarty, B.2    Bossard, P.3    Ferré, P.4    Foufelle, F.5
  • 64
    • 0037959071 scopus 로고    scopus 로고
    • The state of lipid rafts: from model membranes to cells
    • Edidin, M., The state of lipid rafts: from model membranes to cells. Annu. Rev. Biophys. Biomol. Struct. 32 (2003), 257–283.
    • (2003) Annu. Rev. Biophys. Biomol. Struct. , vol.32 , pp. 257-283
    • Edidin, M.1
  • 65
    • 0021753947 scopus 로고
    • Influence of oxygenated sterol compounds on phase-transitions in model membranes—a study by differential scanning calorimetry
    • Egli, U.H., Streuli, R.A., Dubler, E., Influence of oxygenated sterol compounds on phase-transitions in model membranes—a study by differential scanning calorimetry. Biochemistry 23 (1984), 148–152.
    • (1984) Biochemistry , vol.23 , pp. 148-152
    • Egli, U.H.1    Streuli, R.A.2    Dubler, E.3
  • 66
    • 0023260891 scopus 로고
    • Modulation of the phase-transition behavior of phosphatidylethanolamine by cholesterol and oxysterols
    • Epand, R.M., Bottega, R., Modulation of the phase-transition behavior of phosphatidylethanolamine by cholesterol and oxysterols. Biochemistry 26 (1987), 1820–1825.
    • (1987) Biochemistry , vol.26 , pp. 1820-1825
    • Epand, R.M.1    Bottega, R.2
  • 67
    • 33744512299 scopus 로고    scopus 로고
    • Cholesterol and the interaction of proteins with membrane domains
    • Epand, R.M., Cholesterol and the interaction of proteins with membrane domains. Prog. Lipid Res. 45 (2006), 279–294.
    • (2006) Prog. Lipid Res. , vol.45 , pp. 279-294
    • Epand, R.M.1
  • 68
    • 84859847698 scopus 로고    scopus 로고
    • 27-Hydroxycholesterol, does it exist?: On the nomenclature and stereochemistry of 26-hydroxylated sterols
    • Fakheri, R.J., Javitt, N.B., 27-Hydroxycholesterol, does it exist?: On the nomenclature and stereochemistry of 26-hydroxylated sterols. Steroids 77 (2012), 575–577.
    • (2012) Steroids , vol.77 , pp. 575-577
    • Fakheri, R.J.1    Javitt, N.B.2
  • 70
  • 74
    • 0032841514 scopus 로고    scopus 로고
    • Oxysterol efflux from macrophage foam cells: the essential role of acceptor phospholipid
    • Gelissen, I.C., Rye, K.A., Brown, A.J., Dean, R.T., Jessup, W., Oxysterol efflux from macrophage foam cells: the essential role of acceptor phospholipid. J. Lipid Res. 40 (1999), 1636–1646.
    • (1999) J. Lipid Res. , vol.40 , pp. 1636-1646
    • Gelissen, I.C.1    Rye, K.A.2    Brown, A.J.3    Dean, R.T.4    Jessup, W.5
  • 75
    • 53149118574 scopus 로고    scopus 로고
    • Sterol regulators of cholesterol homeostasis and beyond: the oxysterol hypothesis revisited and revised
    • Gill, S., Chow, R., Brown, A.J., Sterol regulators of cholesterol homeostasis and beyond: the oxysterol hypothesis revisited and revised. Prog. Lipid Res. 47 (2008), 391–404.
    • (2008) Prog. Lipid Res. , vol.47 , pp. 391-404
    • Gill, S.1    Chow, R.2    Brown, A.J.3
  • 76
    • 0009627006 scopus 로고
    • Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
    • Goldstein, J.L., Ho, Y.K., Basu, S.K., Brown, M.S., Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proc. Natl. Acad. Sci. 76 (1979), 333–337.
    • (1979) Proc. Natl. Acad. Sci. , vol.76 , pp. 333-337
    • Goldstein, J.L.1    Ho, Y.K.2    Basu, S.K.3    Brown, M.S.4
  • 77
    • 30344473341 scopus 로고    scopus 로고
    • Protein sensors for membrane sterols
    • Goldstein, J.L., DeBose-Boyd, R.A., Brown, M.S., Protein sensors for membrane sterols. Cell 124 (2006), 35–46.
    • (2006) Cell , vol.124 , pp. 35-46
    • Goldstein, J.L.1    DeBose-Boyd, R.A.2    Brown, M.S.3
  • 78
    • 84946097423 scopus 로고    scopus 로고
    • Mitochondrial function and regulation of macrophage sterol metabolism and inflammatory responses
    • Graham, A., Allen, A.-M., Mitochondrial function and regulation of macrophage sterol metabolism and inflammatory responses. World Journal of Cardiology 7 (2015), 277–286.
    • (2015) World Journal of Cardiology , vol.7 , pp. 277-286
    • Graham, A.1    Allen, A.-M.2
  • 79
    • 84884306056 scopus 로고    scopus 로고
    • Methods for oxysterol analysis: past, present and future
    • Griffiths, W.J., Crick, P.J., Wang, Y.Q., Methods for oxysterol analysis: past, present and future. Biochem. Pharmacol. 86 (2013), 3–14.
    • (2013) Biochem. Pharmacol. , vol.86 , pp. 3-14
    • Griffiths, W.J.1    Crick, P.J.2    Wang, Y.Q.3
  • 80
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov, S.I., Greten, F.R., Karin, M., Immunity, inflammation, and cancer. Cell 140 (2010), 883–899.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 82
    • 84915768177 scopus 로고    scopus 로고
    • The comparison of zymosterol vs cholesterol membrane properties—the effect of zymosterol on lipid monolayers
    • Hac-Wydro, K., Wydro, P., Flasinski, M., The comparison of zymosterol vs cholesterol membrane properties—the effect of zymosterol on lipid monolayers. Colloids and Surfaces B-Biointerfaces 123 (2014), 524–532.
    • (2014) Colloids and Surfaces B-Biointerfaces , vol.123 , pp. 524-532
    • Hac-Wydro, K.1    Wydro, P.2    Flasinski, M.3
  • 85
    • 0025359909 scopus 로고
    • Estimation of 26-hydroxycholesterol in serum by high-performance liquid-chromatography and its measurement in patients with atherosclerosis
    • Harikkhan, R., Holmes, R.P., Estimation of 26-hydroxycholesterol in serum by high-performance liquid-chromatography and its measurement in patients with atherosclerosis. J. Steroid Biochem. Mol. Biol. 36 (1990), 351–355.
    • (1990) J. Steroid Biochem. Mol. Biol. , vol.36 , pp. 351-355
    • Harikkhan, R.1    Holmes, R.P.2
  • 87
    • 0021344807 scopus 로고
    • 25-Hydroxysterols increase the permeability of liposomes to CA-2+ and other cations
    • Holmes, R.P., Yoss, N.L., 25-Hydroxysterols increase the permeability of liposomes to CA-2+ and other cations. Biochim. Biophys. Acta 770 (1984), 15–21.
    • (1984) Biochim. Biophys. Acta , vol.770 , pp. 15-21
    • Holmes, R.P.1    Yoss, N.L.2
  • 88
    • 0030060474 scopus 로고    scopus 로고
    • Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages
    • Hulten, L.M., Lindmark, H., Diczfalusy, U., Bjorkhem, I., Ottosson, M., Liu, Y., Bondjers, G., Wiklund, O., Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages. J. Clin. Invest. 97 (1996), 461–468.
    • (1996) J. Clin. Invest. , vol.97 , pp. 461-468
    • Hulten, L.M.1    Lindmark, H.2    Diczfalusy, U.3    Bjorkhem, I.4    Ottosson, M.5    Liu, Y.6    Bondjers, G.7    Wiklund, O.8
  • 89
    • 47149103256 scopus 로고    scopus 로고
    • Cellular sterol trafficking and metabolism: spotlight on structure
    • Ikonen, E., Jansen, M., Cellular sterol trafficking and metabolism: spotlight on structure. Curr. Opin. Cell Biol. 20 (2008), 371–377.
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 371-377
    • Ikonen, E.1    Jansen, M.2
  • 90
    • 38549141572 scopus 로고    scopus 로고
    • Cellular cholesterol trafficking and compartmentalization
    • Ikonen, E., Cellular cholesterol trafficking and compartmentalization. Nat. Rev. Mol. Cell Biol. 9 (2008), 125–138.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 125-138
    • Ikonen, E.1
  • 91
  • 92
    • 84925011456 scopus 로고    scopus 로고
    • 7-Ketocholesterol increases retinal microglial migration, activation, and angiogenicity: a potential pathogenic mechanism underlying age-related macular degeneration
    • Indaram, M., Ma, W.X., Zhao, L., Fariss, R.N., Rodriguez, I.R., Wong, W.T., 7-Ketocholesterol increases retinal microglial migration, activation, and angiogenicity: a potential pathogenic mechanism underlying age-related macular degeneration. Sci. Rep., 5, 2015.
    • (2015) Sci. Rep. , vol.5
    • Indaram, M.1    Ma, W.X.2    Zhao, L.3    Fariss, R.N.4    Rodriguez, I.R.5    Wong, W.T.6
  • 93
    • 38149069055 scopus 로고    scopus 로고
    • Purified NPC1 protein—I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein
    • Infante, R.E., Abi-Mosleh, L., Radhakrishnan, A., Dale, J.D., Brown, M.S., Goldstein, J.L., Purified NPC1 protein—I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein. J. Biol. Chem. 283 (2008), 1052–1063.
    • (2008) J. Biol. Chem. , vol.283 , pp. 1052-1063
    • Infante, R.E.1    Abi-Mosleh, L.2    Radhakrishnan, A.3    Dale, J.D.4    Brown, M.S.5    Goldstein, J.L.6
  • 95
    • 0019841103 scopus 로고
    • 26-Hydroxycholesterol—identification and quantitation in human-serum
    • Javitt, N.B., Kok, E., Burstein, S., Cohen, B., Kutscher, J., 26-Hydroxycholesterol—identification and quantitation in human-serum. J. Biol. Chem. 256 (1981), 2644–2646.
    • (1981) J. Biol. Chem. , vol.256 , pp. 2644-2646
    • Javitt, N.B.1    Kok, E.2    Burstein, S.3    Cohen, B.4    Kutscher, J.5
  • 96
    • 37649021073 scopus 로고    scopus 로고
    • Oxysterols: novel biologic roles for the 21st century
    • Javitt, N.B., Oxysterols: novel biologic roles for the 21st century. Steroids 73 (2008), 149–157.
    • (2008) Steroids , vol.73 , pp. 149-157
    • Javitt, N.B.1
  • 97
    • 84948110783 scopus 로고    scopus 로고
    • Breast cancer and (25R)-26-hydroxycholesterol
    • Javitt, N.B., Breast cancer and (25R)-26-hydroxycholesterol. Steroids 104 (2015), 61–64.
    • (2015) Steroids , vol.104 , pp. 61-64
    • Javitt, N.B.1
  • 98
    • 16844367090 scopus 로고    scopus 로고
    • Perspective—novel routes for metabolism of 7-ketocholesterol
    • Jessup, W., Brown, A.J., Perspective—novel routes for metabolism of 7-ketocholesterol. Rejuvenation Res. 8 (2005), 9–12.
    • (2005) Rejuvenation Res. , vol.8 , pp. 9-12
    • Jessup, W.1    Brown, A.J.2
  • 101
    • 0037324340 scopus 로고    scopus 로고
    • Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
    • Joseph, S.B., Castrillo, A., Laffitte, B.A., Mangelsdorf, D.J., Tontonoz, P., Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat. Med. 9 (2003), 213–219.
    • (2003) Nat. Med. , vol.9 , pp. 213-219
    • Joseph, S.B.1    Castrillo, A.2    Laffitte, B.A.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 102
    • 84863984081 scopus 로고    scopus 로고
    • Biophysics of lipid bilayers containing oxidatively modified phospholipids: insights from fluorescence and EPR experiments and from MD simulations
    • Jurkiewicz, P., Olżyńska, A., Cwiklik, L., Conte, E., Jungwirth, P., Megli, F.M., Hof, M., Biophysics of lipid bilayers containing oxidatively modified phospholipids: insights from fluorescence and EPR experiments and from MD simulations. Biochimica et Biophysica Acta (BBA) Biomembranes 1818 (2012), 2388–2402.
    • (2012) Biochimica et Biophysica Acta (BBA) Biomembranes , vol.1818 , pp. 2388-2402
    • Jurkiewicz, P.1    Olżyńska, A.2    Cwiklik, L.3    Conte, E.4    Jungwirth, P.5    Megli, F.M.6    Hof, M.7
  • 104
    • 84867571439 scopus 로고    scopus 로고
    • Effect of ring-substituted oxysterols on the phase behavior of dipalmitoylphosphatidylcholine membranes
    • Kamal, M.A., Raghunathan, V.A., Effect of ring-substituted oxysterols on the phase behavior of dipalmitoylphosphatidylcholine membranes. European Biophysics Journal with Biophysics Letters 41 (2012), 891–900.
    • (2012) European Biophysics Journal with Biophysics Letters , vol.41 , pp. 891-900
    • Kamal, M.A.1    Raghunathan, V.A.2
  • 105
    • 0026597885 scopus 로고
    • Rates of spontaneous exchange of synthetic radiolabeled sterols between lipid vesicles
    • Kan, C.C., Yan, J.S., Bittman, R., Rates of spontaneous exchange of synthetic radiolabeled sterols between lipid vesicles. Biochemistry 31 (1992), 1866–1874.
    • (1992) Biochemistry , vol.31 , pp. 1866-1874
    • Kan, C.C.1    Yan, J.S.2    Bittman, R.3
  • 106
    • 84926433475 scopus 로고    scopus 로고
    • Oxidation of cholesterol does not alter significantly its uptake into high-Density lipoprotein particles
    • Karilainen, T., Timr, Š., Vattulainen, I., Jungwirth, P., Oxidation of cholesterol does not alter significantly its uptake into high-Density lipoprotein particles. J. Phys. Chem. B 119 (2015), 4594–4600.
    • (2015) J. Phys. Chem. B , vol.119 , pp. 4594-4600
    • Karilainen, T.1    Timr, Š.2    Vattulainen, I.3    Jungwirth, P.4
  • 107
    • 4143090902 scopus 로고    scopus 로고
    • Cholesterol-induced modulated phase in phospholipid membranes
    • Karmakar, S., Raghunathan, V.A., Cholesterol-induced modulated phase in phospholipid membranes. Phys. Rev. Lett., 91, 2003.
    • (2003) Phys. Rev. Lett. , vol.91
    • Karmakar, S.1    Raghunathan, V.A.2
  • 108
    • 27944461106 scopus 로고    scopus 로고
    • Structure of phospholipid-cholesterol membranes: an x-ray diffraction study
    • Karmakar, S., Raghunathan, V.A., Structure of phospholipid-cholesterol membranes: an x-ray diffraction study. Phys. Rev. E, 71, 2005.
    • (2005) Phys. Rev. E , vol.71
    • Karmakar, S.1    Raghunathan, V.A.2
  • 109
    • 0033934567 scopus 로고    scopus 로고
    • Fluorocholesterols, in contrast to hydroxycholesterols, exhibit interfacial properties similar to cholesterol
    • Kauffman, J.M., Westerman, P.W., Carey, M.C., Fluorocholesterols, in contrast to hydroxycholesterols, exhibit interfacial properties similar to cholesterol. J. Lipid Res. 41 (2000), 991–1003.
    • (2000) J. Lipid Res. , vol.41 , pp. 991-1003
    • Kauffman, J.M.1    Westerman, P.W.2    Carey, M.C.3
  • 110
    • 1242319550 scopus 로고    scopus 로고
    • Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome
    • Keller, R.K., Arnold, T.P., Fliesler, S.J., Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome. J. Lipid Res. 45 (2004), 347–355.
    • (2004) J. Lipid Res. , vol.45 , pp. 347-355
    • Keller, R.K.1    Arnold, T.P.2    Fliesler, S.J.3
  • 111
    • 84874586270 scopus 로고    scopus 로고
    • How cholesterol tilt modulates the mechanical properties of saturated and unsaturated lipid membranes
    • Khelashvili, G., Harries, D., How cholesterol tilt modulates the mechanical properties of saturated and unsaturated lipid membranes. J. Phys. Chem. B 117 (2013), 2411–2421.
    • (2013) J. Phys. Chem. B , vol.117 , pp. 2411-2421
    • Khelashvili, G.1    Harries, D.2
  • 112
    • 84876416350 scopus 로고    scopus 로고
    • How sterol tilt regulates properties and organization of lipid membranes and membrane insertions
    • Khelashvili, G., Harries, D., How sterol tilt regulates properties and organization of lipid membranes and membrane insertions. Chem. Phys. Lipids 169 (2013), 113–123.
    • (2013) Chem. Phys. Lipids , vol.169 , pp. 113-123
    • Khelashvili, G.1    Harries, D.2
  • 113
    • 47749155975 scopus 로고    scopus 로고
    • Effects of amyloid beta-peptides on the lysis tension of lipid bilayer vesicles containing oxysterols
    • Kim, D.H., Frangos, J.A., Effects of amyloid beta-peptides on the lysis tension of lipid bilayer vesicles containing oxysterols. Biophys. J. 95 (2008), 620–628.
    • (2008) Biophys. J. , vol.95 , pp. 620-628
    • Kim, D.H.1    Frangos, J.A.2
  • 114
    • 84919934705 scopus 로고    scopus 로고
    • 27-Hydroxycholesterol up-regulates CD14 and predisposes monocytic cells to superproduction of CCL2 in response to lipopolysaccharide
    • Kim, S.-M., Kim, B.-Y., Eo, S.-K., Kim, C.-D., Kim, K., 27-Hydroxycholesterol up-regulates CD14 and predisposes monocytic cells to superproduction of CCL2 in response to lipopolysaccharide. Biochimica Et Biophysica Acta-Molecular Basis of Disease 1852 (2015), 442–450.
    • (2015) Biochimica Et Biophysica Acta-Molecular Basis of Disease , vol.1852 , pp. 442-450
    • Kim, S.-M.1    Kim, B.-Y.2    Eo, S.-K.3    Kim, C.-D.4    Kim, K.5
  • 116
    • 84918520609 scopus 로고    scopus 로고
    • The structural role of cholesterol in cell membranes: from condensed bilayers to lipid rafts
    • Krause, M.R., Regen, S.L., The structural role of cholesterol in cell membranes: from condensed bilayers to lipid rafts. Acc. Chem. Res. 47 (2014), 3512–3521.
    • (2014) Acc. Chem. Res. , vol.47 , pp. 3512-3521
    • Krause, M.R.1    Regen, S.L.2
  • 118
    • 84988983673 scopus 로고    scopus 로고
    • Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue
    • Kreilaus, F., Spiro, A.S., McLean, C.A., Garner, B., Jenner, A.M., Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue. Neuropathol. Appl. Neurobiol., 2015, 12286, 10.1111/nan.12286.
    • (2015) Neuropathol. Appl. Neurobiol. , pp. 12286
    • Kreilaus, F.1    Spiro, A.S.2    McLean, C.A.3    Garner, B.4    Jenner, A.M.5
  • 119
    • 34547923782 scopus 로고    scopus 로고
    • Influence of cholesterol on the bilayer properties of monounsaturated phosphatidylcholine unilamellar vesicles
    • Kučerka, N., Pencer, J., Nieh, M.-P., Katsaras, J., Influence of cholesterol on the bilayer properties of monounsaturated phosphatidylcholine unilamellar vesicles. Eur. Phys. J. E 23 (2007), 247–254.
    • (2007) Eur. Phys. J. E , vol.23 , pp. 247-254
    • Kučerka, N.1    Pencer, J.2    Nieh, M.-P.3    Katsaras, J.4
  • 125
    • 0036534286 scopus 로고    scopus 로고
    • The sterol-sensing domain: multiple families, a unique role?
    • Kuwabara, P.E., Labouesse, M., The sterol-sensing domain: multiple families, a unique role?. Trends Genet. 18 (2002), 193–201.
    • (2002) Trends Genet. , vol.18 , pp. 193-201
    • Kuwabara, P.E.1    Labouesse, M.2
  • 126
    • 44949133956 scopus 로고    scopus 로고
    • Cholesterol homeostasis and the escape tendency (activity) of plasma membrane cholesterol
    • Lange, Y., Steck, T.L., Cholesterol homeostasis and the escape tendency (activity) of plasma membrane cholesterol. Prog. Lipid Res. 47 (2008), 319–332.
    • (2008) Prog. Lipid Res. , vol.47 , pp. 319-332
    • Lange, Y.1    Steck, T.L.2
  • 127
    • 0028999147 scopus 로고
    • Movement of 25-hydroxycholesterol from the plasma-membrane to the rough endoplasmic-reticulum in cultured hepatoma-cells
    • Lange, Y., Ye, J., Strebel, F., Movement of 25-hydroxycholesterol from the plasma-membrane to the rough endoplasmic-reticulum in cultured hepatoma-cells. J. Lipid Res. 36 (1995), 1092–1097.
    • (1995) J. Lipid Res. , vol.36 , pp. 1092-1097
    • Lange, Y.1    Ye, J.2    Strebel, F.3
  • 128
    • 0033384957 scopus 로고    scopus 로고
    • Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol
    • Lange, Y., Ye, J., Rigney, M., Steck, T.L., Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol. J. Lipid Res. 40 (1999), 2264–2270.
    • (1999) J. Lipid Res. , vol.40 , pp. 2264-2270
    • Lange, Y.1    Ye, J.2    Rigney, M.3    Steck, T.L.4
  • 129
    • 4143069270 scopus 로고    scopus 로고
    • How cholesterol homeostasis is regulated by plasma membrane cholesterol in excess of phospholipids
    • Lange, Y., Ye, J., Steck, T.L., How cholesterol homeostasis is regulated by plasma membrane cholesterol in excess of phospholipids. Proc. Natl. Acad. Sci. U.S.A. 101 (2004), 11664–11667.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 11664-11667
    • Lange, Y.1    Ye, J.2    Steck, T.L.3
  • 130
    • 84899097056 scopus 로고    scopus 로고
    • Atherosclerosis and Alzheimer – diseases with a common cause? Inflammation, oxysterols, vasculature
    • Lathe, R., Sapronova, A., Kotelevtsev, Y., Atherosclerosis and Alzheimer – diseases with a common cause? Inflammation, oxysterols, vasculature. BMC Geriatrics, 14, 2014, 36, 10.1186/1471-2318-14-36.
    • (2014) BMC Geriatrics , vol.14 , pp. 36
    • Lathe, R.1    Sapronova, A.2    Kotelevtsev, Y.3
  • 131
    • 84919787556 scopus 로고    scopus 로고
    • The interaction between metabolism, cancer and cardiovascular disease, connected by 27-hydroxycholesterol
    • Lee, W.-R., Ishikawa, T., Umetani, M., The interaction between metabolism, cancer and cardiovascular disease, connected by 27-hydroxycholesterol. Clinical Lipidology 9 (2014), 617–624.
    • (2014) Clinical Lipidology , vol.9 , pp. 617-624
    • Lee, W.-R.1    Ishikawa, T.2    Umetani, M.3
  • 132
    • 0024295212 scopus 로고
    • Effect of 7β-hydroxycholesterol on growth and membrane composition of Mycoplasma capricolum
    • Lelong, I., Luu, B., Mersel, M., Rottem, S., Effect of 7β-hydroxycholesterol on growth and membrane composition of Mycoplasma capricolum. FEBS Lett. 232 (1988), 354–358.
    • (1988) FEBS Lett. , vol.232 , pp. 354-358
    • Lelong, I.1    Luu, B.2    Mersel, M.3    Rottem, S.4
  • 133
    • 0032421830 scopus 로고    scopus 로고
    • Different patterns of IL-1β secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7α-, 7β-hydroxycholesterol, or 7-Ketocholesterol
    • Lemaire, S., Lizard, G., Monier, S., Miguet, C., Gueldry, S., Volot, F., Gambert, P., Néel, D., Different patterns of IL-1β secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7α-, 7β-hydroxycholesterol, or 7-Ketocholesterol. FEBS Lett. 440 (1998), 434–439.
    • (1998) FEBS Lett. , vol.440 , pp. 434-439
    • Lemaire, S.1    Lizard, G.2    Monier, S.3    Miguet, C.4    Gueldry, S.5    Volot, F.6    Gambert, P.7    Néel, D.8
  • 134
    • 65349111246 scopus 로고    scopus 로고
    • 7β-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent
    • Lemaire-Ewing, S., Berthier, A., Royer, M.C., Logette, E., Corcos, L., Bouchot, A., Monier, S., Prunet, C., Raveneau, M., Rébé, C., Desrumaux, C., Lizard, G., Néel, D., 7β-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent. Cell Biol. Toxicol. 25 (2009), 127–139.
    • (2009) Cell Biol. Toxicol. , vol.25 , pp. 127-139
    • Lemaire-Ewing, S.1    Berthier, A.2    Royer, M.C.3    Logette, E.4    Corcos, L.5    Bouchot, A.6    Monier, S.7    Prunet, C.8    Raveneau, M.9    Rébé, C.10    Desrumaux, C.11    Lizard, G.12    Néel, D.13
  • 135
    • 0036903407 scopus 로고    scopus 로고
    • Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review)
    • Leonarduzzi, G., Sottero, B., Poli, G., Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review). J. Nutr. Biochem. 13 (2002), 700–710.
    • (2002) J. Nutr. Biochem. , vol.13 , pp. 700-710
    • Leonarduzzi, G.1    Sottero, B.2    Poli, G.3
  • 136
    • 1642422735 scopus 로고    scopus 로고
    • Trojan horse-like behavior of a biologically representative mixture of oxysterols
    • Leonarduzzi, G., Biasi, F., Chiarpotto, E., Poli, G., Trojan horse-like behavior of a biologically representative mixture of oxysterols. Mol. Aspects Med. 25 (2004), 155–167.
    • (2004) Mol. Aspects Med. , vol.25 , pp. 155-167
    • Leonarduzzi, G.1    Biasi, F.2    Chiarpotto, E.3    Poli, G.4
  • 138
    • 80051472136 scopus 로고    scopus 로고
    • Oxysterols as biomarkers in neurodegenerative diseases
    • Leoni, V., Caccia, C., Oxysterols as biomarkers in neurodegenerative diseases. Chem. Phys. Lipids 164 (2011), 515–524.
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 515-524
    • Leoni, V.1    Caccia, C.2
  • 142
    • 0345413250 scopus 로고    scopus 로고
    • Sterol structure and sphingomyelin acyl chain length modulate lateral packing elasticity and detergent solubility in model membranes
    • Li, X.M., Momsen, M.M., Brockman, H.L., Brown, R.E., Sterol structure and sphingomyelin acyl chain length modulate lateral packing elasticity and detergent solubility in model membranes. Biophys. J. 85 (2003), 3788–3801.
    • (2003) Biophys. J. , vol.85 , pp. 3788-3801
    • Li, X.M.1    Momsen, M.M.2    Brockman, H.L.3    Brown, R.E.4
  • 143
    • 33644634175 scopus 로고    scopus 로고
    • Foam cell death induced by 7 beta-hydroxycholesterol is mediated by labile iron-driven oxidative injury: mechanisms underlying induction of ferritin in human atheroma
    • Li, W., Hellsten, A., Xu, L.H., Zhuang, D.M., Jansson, K., Brunk, U.T., Yuan, X.M., Foam cell death induced by 7 beta-hydroxycholesterol is mediated by labile iron-driven oxidative injury: mechanisms underlying induction of ferritin in human atheroma. Free Radic. Biol. Med. 39 (2005), 864–875.
    • (2005) Free Radic. Biol. Med. , vol.39 , pp. 864-875
    • Li, W.1    Hellsten, A.2    Xu, L.H.3    Zhuang, D.M.4    Jansson, K.5    Brunk, U.T.6    Yuan, X.M.7
  • 144
    • 22744437388 scopus 로고    scopus 로고
    • Detergent-resistant membranes should not be identified with membrane rafts
    • Lichtenberg, D., Goni, F.M., Heerklotz, H., Detergent-resistant membranes should not be identified with membrane rafts. Trends Biochem. Sci. 30 (2005), 430–436.
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 430-436
    • Lichtenberg, D.1    Goni, F.M.2    Heerklotz, H.3
  • 148
    • 0034022635 scopus 로고    scopus 로고
    • Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-Ketocholesterol-induced apoptosis
    • Lizard, G., Miguet, C., Besséde, G., Monier, S., Gueldry, S., Neel, D., Gambert, P., Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-Ketocholesterol-induced apoptosis. Free Radic. Biol. Med. 28 (2000), 743–753.
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 743-753
    • Lizard, G.1    Miguet, C.2    Besséde, G.3    Monier, S.4    Gueldry, S.5    Neel, D.6    Gambert, P.7
  • 151
    • 80051469291 scopus 로고    scopus 로고
    • Oxysterols and calcium signal transduction
    • Mackrill, J.J., Oxysterols and calcium signal transduction. Chem. Phys. Lipids 164 (2011), 488–495.
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 488-495
    • Mackrill, J.J.1
  • 153
    • 77954215798 scopus 로고    scopus 로고
    • The effect of variations in phospholipid and sterol structure on the nature of lipid-sterol interactions in lipid bilayer model membranes
    • Mannock, D.A., Lewis, R.N.A.H., McMullen, T.P.W., McElhaney, R.N., The effect of variations in phospholipid and sterol structure on the nature of lipid-sterol interactions in lipid bilayer model membranes. Chem. Phys. Lipids 163 (2010), 403–448.
    • (2010) Chem. Phys. Lipids , vol.163 , pp. 403-448
    • Mannock, D.A.1    Lewis, R.N.A.H.2    McMullen, T.P.W.3    McElhaney, R.N.4
  • 156
    • 84941313899 scopus 로고    scopus 로고
    • Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap?
    • Marwarha, G., Ghribi, O., Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap?. Exp. Gerontol. 68 (2015), 13–18.
    • (2015) Exp. Gerontol. , vol.68 , pp. 13-18
    • Marwarha, G.1    Ghribi, O.2
  • 157
    • 23044515913 scopus 로고    scopus 로고
    • The polar nature of 7-Ketocholesterol determines its location within membrane domains and the kinetics of membrane micro solubilization by apolipoprotein A-I
    • Massey, J.B., Pownall, H.J., The polar nature of 7-Ketocholesterol determines its location within membrane domains and the kinetics of membrane micro solubilization by apolipoprotein A-I. Biochemistry 44 (2005), 10423–10433.
    • (2005) Biochemistry , vol.44 , pp. 10423-10433
    • Massey, J.B.1    Pownall, H.J.2
  • 158
    • 27444434358 scopus 로고    scopus 로고
    • Role of oxysterol structure on the microdomain-induced microsolubilization of phospholipid membranes by apolipoprotein A-I
    • Massey, J.B., Pownall, H.J., Role of oxysterol structure on the microdomain-induced microsolubilization of phospholipid membranes by apolipoprotein A-I. Biochemistry 44 (2005), 14376–14384.
    • (2005) Biochemistry , vol.44 , pp. 14376-14384
    • Massey, J.B.1    Pownall, H.J.2
  • 159
    • 33748249320 scopus 로고    scopus 로고
    • Structures of biologically active oxysterols determine their differential effects on phospholipid membranes
    • Massey, J.B., Pownall, H.J., Structures of biologically active oxysterols determine their differential effects on phospholipid membranes. Biochemistry 45 (2006), 10747–10758.
    • (2006) Biochemistry , vol.45 , pp. 10747-10758
    • Massey, J.B.1    Pownall, H.J.2
  • 160
    • 33646864114 scopus 로고    scopus 로고
    • Membrane and protein interactions of oxysterols
    • Massey, J.B., Membrane and protein interactions of oxysterols. Curr. Opin. Lipidol. 17 (2006), 296–301.
    • (2006) Curr. Opin. Lipidol. , vol.17 , pp. 296-301
    • Massey, J.B.1
  • 161
    • 28444479505 scopus 로고    scopus 로고
    • Role of cholesterol and lipid organization in disease
    • Maxfield, F.R., Tabas, I., Role of cholesterol and lipid organization in disease. Nature 438 (2005), 612–621.
    • (2005) Nature , vol.438 , pp. 612-621
    • Maxfield, F.R.1    Tabas, I.2
  • 162
    • 0036916491 scopus 로고    scopus 로고
    • On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: critical importance of the position of the oxygen function
    • Meaney, S., Bodin, K., Diczfalusy, U., Bjorkhem, I., On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: critical importance of the position of the oxygen function. J. Lipid Res. 43 (2002), 2130–2135.
    • (2002) J. Lipid Res. , vol.43 , pp. 2130-2135
    • Meaney, S.1    Bodin, K.2    Diczfalusy, U.3    Bjorkhem, I.4
  • 163
    • 79960253885 scopus 로고    scopus 로고
    • Function of MRP1/ABCC1 is not dependent on cholesterol or cholesterol-stabilized lipid rafts
    • Meszaros, P., Klappe, K., Hummel, I., Hoekstra, D., Kok, J.W., Function of MRP1/ABCC1 is not dependent on cholesterol or cholesterol-stabilized lipid rafts. Biochem. J 437 (2011), 483–491.
    • (2011) Biochem. J , vol.437 , pp. 483-491
    • Meszaros, P.1    Klappe, K.2    Hummel, I.3    Hoekstra, D.4    Kok, J.W.5
  • 164
    • 26244436216 scopus 로고    scopus 로고
    • Dietary oxysterols induce in vivo toxicity of coronary endothelial and smooth muscle cells
    • Meynier, A., Andre, A., Lherminier, J., Grandgirard, A., Demaison, L., Dietary oxysterols induce in vivo toxicity of coronary endothelial and smooth muscle cells. Eur. J. Nutr. 44 (2005), 393–405.
    • (2005) Eur. J. Nutr. , vol.44 , pp. 393-405
    • Meynier, A.1    Andre, A.2    Lherminier, J.3    Grandgirard, A.4    Demaison, L.5
  • 165
    • 84878358772 scopus 로고    scopus 로고
    • Expression of Egr1 and p53 in human carotid plaques and apoptosis induced by 7-oxysterol or p53
    • Miah, S., Zadeh, S.N.M., Yuan, X.-M., Li, W., Expression of Egr1 and p53 in human carotid plaques and apoptosis induced by 7-oxysterol or p53. Exp. Toxicol. Pathol. 65 (2013), 677–682.
    • (2013) Exp. Toxicol. Pathol. , vol.65 , pp. 677-682
    • Miah, S.1    Zadeh, S.N.M.2    Yuan, X.-M.3    Li, W.4
  • 166
    • 0034746291 scopus 로고    scopus 로고
    • Ceramide generation occurring during 7 beta-hydroxycholesterol- and 7-Ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death
    • Miguet, C., Monier, S., Bettaieb, A., Athias, A., Bessede, G., Laubriet, A., Lemaire, S., Neel, D., Gambert, P., Lizard, G., Ceramide generation occurring during 7 beta-hydroxycholesterol- and 7-Ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. Cell Death Differ. 8 (2001), 83–99.
    • (2001) Cell Death Differ. , vol.8 , pp. 83-99
    • Miguet, C.1    Monier, S.2    Bettaieb, A.3    Athias, A.4    Bessede, G.5    Laubriet, A.6    Lemaire, S.7    Neel, D.8    Gambert, P.9    Lizard, G.10
  • 167
    • 77954217091 scopus 로고    scopus 로고
    • Interaction of two oxysterols, 7-Ketocholesterol and 25-hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes
    • Mintzer, E., Charles, G., Gordon, S., Interaction of two oxysterols, 7-Ketocholesterol and 25-hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes. Chem. Phys. Lipids 163 (2010), 586–593.
    • (2010) Chem. Phys. Lipids , vol.163 , pp. 586-593
    • Mintzer, E.1    Charles, G.2    Gordon, S.3
  • 168
    • 69349083785 scopus 로고    scopus 로고
    • Oxysterol-Induced rearrangement of the liquid-Ordered phase: a possible link to alzheimer's disease?
    • Mitomo, H., Chen, W.-H., Regen, S.L., Oxysterol-Induced rearrangement of the liquid-Ordered phase: a possible link to alzheimer's disease?. J. Amer. Chem. Soc. 131 (2009), 12354–12357.
    • (2009) J. Amer. Chem. Soc. , vol.131 , pp. 12354-12357
    • Mitomo, H.1    Chen, W.-H.2    Regen, S.L.3
  • 169
    • 0030904025 scopus 로고    scopus 로고
    • Plasma levels of lipid and cholesterol oxidation products and cytokines in diabetes mellitus and cigarette smoking: effects of vitamin E treatment
    • Mol, M., deRijke, Y.B., Demacker, P.N.M., Stalenhoef, A.F.H., Plasma levels of lipid and cholesterol oxidation products and cytokines in diabetes mellitus and cigarette smoking: effects of vitamin E treatment. Atherosclerosis 129 (1997), 169–176.
    • (1997) Atherosclerosis , vol.129 , pp. 169-176
    • Mol, M.1    deRijke, Y.B.2    Demacker, P.N.M.3    Stalenhoef, A.F.H.4
  • 171
    • 0019420840 scopus 로고
    • Biosynthesis of 24,25-epoxycholesterol from squalene 2,3-22,23-dioxide
    • Nelson, J.A., Steckbeck, S.R., Spencer, T.A., Biosynthesis of 24,25-epoxycholesterol from squalene 2,3-22,23-dioxide. J. Biol. Chem. 256 (1981), 1067–1068.
    • (1981) J. Biol. Chem. , vol.256 , pp. 1067-1068
    • Nelson, J.A.1    Steckbeck, S.R.2    Spencer, T.A.3
  • 174
    • 0031662217 scopus 로고    scopus 로고
    • Oxidation of lipids in low density lipoprotein particles
    • Noguchi, N., Numano, R., Kaneda, H., Niki, E., Oxidation of lipids in low density lipoprotein particles. Free Radic. Res. 29 (1998), 43–52.
    • (1998) Free Radic. Res. , vol.29 , pp. 43-52
    • Noguchi, N.1    Numano, R.2    Kaneda, H.3    Niki, E.4
  • 177
    • 0036090607 scopus 로고    scopus 로고
    • Characteristics of 7’-hydroxycholesterol-induced cell death in a human monocytic blood cell line, U937, and a human hepatoma cell line, HepG2
    • O'Callaghan, Y.C., Woods, J.A., O'Brien, N.M., Characteristics of 7’-hydroxycholesterol-induced cell death in a human monocytic blood cell line, U937, and a human hepatoma cell line, HepG2. Toxicol. In Vitro 16 (2002), 245–251.
    • (2002) Toxicol. In Vitro , vol.16 , pp. 245-251
    • O'Callaghan, Y.C.1    Woods, J.A.2    O'Brien, N.M.3
  • 179
    • 67349262029 scopus 로고    scopus 로고
    • Interactions of oxysterols with membranes and proteins
    • Olkkonen, V.M., Hynynen, R., Interactions of oxysterols with membranes and proteins. Mol. Aspects Med. 30 (2009), 123–133.
    • (2009) Mol. Aspects Med. , vol.30 , pp. 123-133
    • Olkkonen, V.M.1    Hynynen, R.2
  • 180
    • 11144233997 scopus 로고    scopus 로고
    • Oxysterols and oxysterol binding proteins: role in lipid metabolism and atherosclerosis
    • Olkkonen, V.M., Lehto, M., Oxysterols and oxysterol binding proteins: role in lipid metabolism and atherosclerosis. Ann. Med. 36 (2004), 562–572.
    • (2004) Ann. Med. , vol.36 , pp. 562-572
    • Olkkonen, V.M.1    Lehto, M.2
  • 181
    • 85016356885 scopus 로고    scopus 로고
    • Oxysterols and their cellular effectors
    • Olkkonen, V.M., Beaslas, O., Nissila, E., Oxysterols and their cellular effectors. Biomolecules 2 (2012), 76–103.
    • (2012) Biomolecules , vol.2 , pp. 76-103
    • Olkkonen, V.M.1    Beaslas, O.2    Nissila, E.3
  • 182
    • 84866325411 scopus 로고    scopus 로고
    • Macrophage oxysterols and their binding proteins: roles in atherosclerosis
    • Olkkonen, V.M., Macrophage oxysterols and their binding proteins: roles in atherosclerosis. Curr. Opin. Lipidol. 23 (2012), 462–470.
    • (2012) Curr. Opin. Lipidol. , vol.23 , pp. 462-470
    • Olkkonen, V.M.1
  • 183
    • 67949098831 scopus 로고    scopus 로고
    • Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation
    • Olsen, B.N., Schlesinger, P.H., Baker, N.A., Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation. J. Amer. Chem. Soc. 131 (2009), 4854–4865.
    • (2009) J. Amer. Chem. Soc. , vol.131 , pp. 4854-4865
    • Olsen, B.N.1    Schlesinger, P.H.2    Baker, N.A.3
  • 184
    • 79951839943 scopus 로고    scopus 로고
    • 25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranes
    • Olsen, B.N., Schlesinger, P.H., Ory, D.S., Baker, N.A., 25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranes. Biophys. J. 100 (2011), 948–956.
    • (2011) Biophys. J. , vol.100 , pp. 948-956
    • Olsen, B.N.1    Schlesinger, P.H.2    Ory, D.S.3    Baker, N.A.4
  • 189
    • 0034780429 scopus 로고    scopus 로고
    • Mechanisms of oxysterol-induced apoptosis
    • Panini, S.R., Sinensky, M.S., Mechanisms of oxysterol-induced apoptosis. Curr. Opin. Lipidol. 12 (2001), 529–533.
    • (2001) Curr. Opin. Lipidol. , vol.12 , pp. 529-533
    • Panini, S.R.1    Sinensky, M.S.2
  • 190
    • 84864220156 scopus 로고    scopus 로고
    • Flip-Flop of steroids in phospholipid bilayers: effects of the chemical structure on transbilayer diffusion
    • Parisio, G., Sperotto, M.M., Ferrarini, A., Flip-Flop of steroids in phospholipid bilayers: effects of the chemical structure on transbilayer diffusion. J. Amer. Chem. Soc. 134 (2012), 12198–12208.
    • (2012) J. Amer. Chem. Soc. , vol.134 , pp. 12198-12208
    • Parisio, G.1    Sperotto, M.M.2    Ferrarini, A.3
  • 191
    • 84947042506 scopus 로고    scopus 로고
    • Cholesterol—a putative endogenous contributor towards Parkinson's disease
    • Paul, R., Choudhury, A., Borah, A., Cholesterol—a putative endogenous contributor towards Parkinson's disease. Neurochem. Int. 90 (2015), 125–133.
    • (2015) Neurochem. Int. , vol.90 , pp. 125-133
    • Paul, R.1    Choudhury, A.2    Borah, A.3
  • 192
    • 70450183660 scopus 로고    scopus 로고
    • Inhibiting lateral domain formation in lipid bilayers: simulations of alternative steroid headgroup chemistries
    • Perlmutter, J.D., Sachs, J.N., Inhibiting lateral domain formation in lipid bilayers: simulations of alternative steroid headgroup chemistries. J. Amer. Chem. Soc., 131, 2009, 16362.
    • (2009) J. Amer. Chem. Soc. , vol.131 , pp. 16362
    • Perlmutter, J.D.1    Sachs, J.N.2
  • 193
    • 33744728346 scopus 로고    scopus 로고
    • Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein
    • Perry, R.J., Ridgway, N.D., Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein. Mol. Biol. Cell 17 (2006), 2604–2616.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 2604-2616
    • Perry, R.J.1    Ridgway, N.D.2
  • 195
    • 0034751268 scopus 로고    scopus 로고
    • 7-Ketocholesterol forms crystalline domains in model membranes and murine aortic smooth muscle cells
    • Phillips, J.E., Geng, Y.J., Mason, R.P., 7-Ketocholesterol forms crystalline domains in model membranes and murine aortic smooth muscle cells. Atherosclerosis 159 (2001), 125–135.
    • (2001) Atherosclerosis , vol.159 , pp. 125-135
    • Phillips, J.E.1    Geng, Y.J.2    Mason, R.P.3
  • 196
    • 67349248123 scopus 로고    scopus 로고
    • Cholesterol oxidation products in the vascular remodeling due to atherosclerosis
    • Poli, G., Sottero, B., Gargiulo, S., Leonarduzzi, G., Cholesterol oxidation products in the vascular remodeling due to atherosclerosis. Mol. Aspects Med. 30 (2009), 180–189.
    • (2009) Mol. Aspects Med. , vol.30 , pp. 180-189
    • Poli, G.1    Sottero, B.2    Gargiulo, S.3    Leonarduzzi, G.4
  • 198
    • 2942707855 scopus 로고    scopus 로고
    • Formation of biologically active oxysterols during ozonolysis of cholesterol present in lung surfactant
    • Pulfer, M.K., Murphy, R.C., Formation of biologically active oxysterols during ozonolysis of cholesterol present in lung surfactant. J. Biol. Chem. 279 (2004), 26331–26338.
    • (2004) J. Biol. Chem. , vol.279 , pp. 26331-26338
    • Pulfer, M.K.1    Murphy, R.C.2
  • 199
    • 84910019812 scopus 로고    scopus 로고
    • Cholesterol, sphingolipids, and glycolipids: what do we know about their role in raft-like membranes?
    • Róg, T., Vattulainen, I., Cholesterol, sphingolipids, and glycolipids: what do we know about their role in raft-like membranes?. Chem. Phys. Lipids 184 (2014), 82–104.
    • (2014) Chem. Phys. Lipids , vol.184 , pp. 82-104
    • Róg, T.1    Vattulainen, I.2
  • 200
    • 34249848111 scopus 로고    scopus 로고
    • Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig
    • Radhakrishnan, A., Ikeda, Y., Kwon, H.J., Brown, M.S., Goldstein, J.L., Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig. Proc. Natl. Acad. Sci. U.S.A. 104 (2007), 6511–6518.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 6511-6518
    • Radhakrishnan, A.1    Ikeda, Y.2    Kwon, H.J.3    Brown, M.S.4    Goldstein, J.L.5
  • 201
    • 56749183934 scopus 로고    scopus 로고
    • Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells
    • Rantham Prabhakara, J.P., Feist, G., Thomasson, S., Thompson, A., Schommer, E., Ghribi, O., Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells. J. Neurochem. 107 (2008), 1722–1729.
    • (2008) J. Neurochem. , vol.107 , pp. 1722-1729
    • Rantham Prabhakara, J.P.1    Feist, G.2    Thomasson, S.3    Thompson, A.4    Schommer, E.5    Ghribi, O.6
  • 203
    • 77956800486 scopus 로고    scopus 로고
    • Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration
    • Rodriguez, I.R., Larrayoz, I.M., Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration. J. Lipid Res. 51 (2010), 2847–2862.
    • (2010) J. Lipid Res. , vol.51 , pp. 2847-2862
    • Rodriguez, I.R.1    Larrayoz, I.M.2
  • 204
    • 34247893965 scopus 로고    scopus 로고
    • What happens if cholesterol is made smoother: importance of methyl substituents in cholesterol ring structure on phosphatidylcholine-sterol interaction
    • Rog, T., Pasenkiewicz-Gierula, M., Vattulainen, I., Karttunen, M., What happens if cholesterol is made smoother: importance of methyl substituents in cholesterol ring structure on phosphatidylcholine-sterol interaction. Biophys. J. 92 (2007), 3346–3357.
    • (2007) Biophys. J. , vol.92 , pp. 3346-3357
    • Rog, T.1    Pasenkiewicz-Gierula, M.2    Vattulainen, I.3    Karttunen, M.4
  • 205
    • 39849097393 scopus 로고    scopus 로고
    • Replacing the cholesterol hydroxyl group with the ketone group facilitates sterol flip-flop and promotes membrane fluidity
    • Rog, T., Stimson, L.M., Pasenkiewicz-Gierula, M., Vattulainen, I., Karttunen, M., Replacing the cholesterol hydroxyl group with the ketone group facilitates sterol flip-flop and promotes membrane fluidity. J. Phys. Chem. B 112 (2008), 1946–1952.
    • (2008) J. Phys. Chem. B , vol.112 , pp. 1946-1952
    • Rog, T.1    Stimson, L.M.2    Pasenkiewicz-Gierula, M.3    Vattulainen, I.4    Karttunen, M.5
  • 206
    • 54849403535 scopus 로고    scopus 로고
    • Comparison of cholesterol and its direct precursors along the biosynthetic pathway: effects of cholesterol, desmosterol and 7-dehydrocholesterol on saturated and unsaturated lipid bilayers
    • Rog, T., Vattulainen, I., Jansen, M., Ikonen, E., Karttunen, M., Comparison of cholesterol and its direct precursors along the biosynthetic pathway: effects of cholesterol, desmosterol and 7-dehydrocholesterol on saturated and unsaturated lipid bilayers. J. Chem. Phys., 129, 2008.
    • (2008) J. Chem. Phys. , vol.129
    • Rog, T.1    Vattulainen, I.2    Jansen, M.3    Ikonen, E.4    Karttunen, M.5
  • 208
  • 209
    • 0022762174 scopus 로고
    • The influence of oxygenated sterol compounds on dipalmitoylphosphatidylcholine bilayer structure and packing
    • Rooney, M., Tamuralis, W., Lis, L.J., Yachnin, S., Kucuk, O., Kauffman, J.W., The influence of oxygenated sterol compounds on dipalmitoylphosphatidylcholine bilayer structure and packing. Chem. Phys. Lipids 41 (1986), 81–92.
    • (1986) Chem. Phys. Lipids , vol.41 , pp. 81-92
    • Rooney, M.1    Tamuralis, W.2    Lis, L.J.3    Yachnin, S.4    Kucuk, O.5    Kauffman, J.W.6
  • 210
    • 0036145210 scopus 로고    scopus 로고
    • Oxysterol-induced activation of macrophage NADPH-oxidase enhances cell-mediated oxidation of LDL in the atherosclerotic apolipoprotein E deficient mouse: inhibitory role for vitamin E
    • Rosenblat, M., Aviram, M., Oxysterol-induced activation of macrophage NADPH-oxidase enhances cell-mediated oxidation of LDL in the atherosclerotic apolipoprotein E deficient mouse: inhibitory role for vitamin E. Atherosclerosis 160 (2002), 69–80.
    • (2002) Atherosclerosis , vol.160 , pp. 69-80
    • Rosenblat, M.1    Aviram, M.2
  • 211
    • 39049183720 scopus 로고    scopus 로고
    • Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7 beta-hydroxycholesterol and 7 beta-hydroxysitosterol
    • Roussi, S., Gosse, F., Aoude-Werner, D., Zhang, X., Geoffroy, P., Miesch, M., Marchioni, E., Raul, F., Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7 beta-hydroxycholesterol and 7 beta-hydroxysitosterol. Int. J. Oncol. 29 (2006), 1549–1554.
    • (2006) Int. J. Oncol. , vol.29 , pp. 1549-1554
    • Roussi, S.1    Gosse, F.2    Aoude-Werner, D.3    Zhang, X.4    Geoffroy, P.5    Miesch, M.6    Marchioni, E.7    Raul, F.8
  • 212
    • 33845733075 scopus 로고    scopus 로고
    • Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7 beta-hydroxysitosterol and 7 beta-hydroxycholesterol triggered apoptosis in human colon cancer cells
    • Roussi, S., Gosse, F., Aoude-Werner, D., Zhang, X., Marchioni, E., Geoffroy, P., Miesch, M., Raul, F., Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7 beta-hydroxysitosterol and 7 beta-hydroxycholesterol triggered apoptosis in human colon cancer cells. Apoptosis 12 (2007), 87–96.
    • (2007) Apoptosis , vol.12 , pp. 87-96
    • Roussi, S.1    Gosse, F.2    Aoude-Werner, D.3    Zhang, X.4    Marchioni, E.5    Geoffroy, P.6    Miesch, M.7    Raul, F.8
  • 214
    • 34548127856 scopus 로고    scopus 로고
    • Cholesterol is more susceptible to oxidation than linoleates in cultured cells under oxidative stress induced by selenium deficiency and free radicals
    • Saito, Y., Yoshida, Y., Niki, E., Cholesterol is more susceptible to oxidation than linoleates in cultured cells under oxidative stress induced by selenium deficiency and free radicals. FEBS Lett. 581 (2007), 4349–4354.
    • (2007) FEBS Lett. , vol.581 , pp. 4349-4354
    • Saito, Y.1    Yoshida, Y.2    Niki, E.3
  • 215
    • 43049090105 scopus 로고    scopus 로고
    • Fatty acid contents evolution and cholesterol oxides formation in Brazilian sardines (Sardinella brasiliensis) as a result of frozen storage followed by grilling
    • Saldanha, T., Benassi, M.T., Bragagnolo, N., Fatty acid contents evolution and cholesterol oxides formation in Brazilian sardines (Sardinella brasiliensis) as a result of frozen storage followed by grilling. LWT Food Sci. Technol. 41 (2008), 1301–1309.
    • (2008) LWT Food Sci. Technol. , vol.41 , pp. 1301-1309
    • Saldanha, T.1    Benassi, M.T.2    Bragagnolo, N.3
  • 218
    • 0342316532 scopus 로고    scopus 로고
    • Oxysterols: modulators of cholesterol metabolism and other processes
    • Schroepfer, G.J., Oxysterols: modulators of cholesterol metabolism and other processes. Physiol. Rev. 80 (2000), 361–554.
    • (2000) Physiol. Rev. , vol.80 , pp. 361-554
    • Schroepfer, G.J.1
  • 223
    • 77958057683 scopus 로고    scopus 로고
    • Macrophages, oxysterols and atherosclerosis
    • Shibata, N., Glass, C.K., Macrophages, oxysterols and atherosclerosis. Circ. J. 74 (2010), 2045–2051.
    • (2010) Circ. J. , vol.74 , pp. 2045-2051
    • Shibata, N.1    Glass, C.K.2
  • 224
    • 0026522024 scopus 로고
    • Modulation of the interbilayer hydration pressure by the addition of dipoles at the hydrocarbon water interface
    • Simon, S.A., McIntosh, T.J., Magid, A.D., Needham, D., Modulation of the interbilayer hydration pressure by the addition of dipoles at the hydrocarbon water interface. Biophys. J. 61 (1992), 786–799.
    • (1992) Biophys. J. , vol.61 , pp. 786-799
    • Simon, S.A.1    McIntosh, T.J.2    Magid, A.D.3    Needham, D.4
  • 225
    • 0034529050 scopus 로고    scopus 로고
    • Cell biology—How cells handle cholesterol
    • Simons, K., Ikonen, E., Cell biology—How cells handle cholesterol. Science 290 (2000), 1721–1726.
    • (2000) Science , vol.290 , pp. 1721-1726
    • Simons, K.1    Ikonen, E.2
  • 227
    • 0028100636 scopus 로고
    • Cholesterols interfacial interactions with sphingomyelins and phosphatidylcholines—hydrocarbon chain structure determines the magnitude of condensation
    • Smaby, J.M., Brockman, H.L., Brown, R.E., Cholesterols interfacial interactions with sphingomyelins and phosphatidylcholines—hydrocarbon chain structure determines the magnitude of condensation. Biochemistry 33 (1994), 9135–9142.
    • (1994) Biochemistry , vol.33 , pp. 9135-9142
    • Smaby, J.M.1    Brockman, H.L.2    Brown, R.E.3
  • 228
    • 0034881633 scopus 로고    scopus 로고
    • Effects of oxygenated sterol on phospholipid bilayer properties: a molecular dynamics simulation
    • Smondyrev, A.M., Berkowitz, M.L., Effects of oxygenated sterol on phospholipid bilayer properties: a molecular dynamics simulation. Chem. Phys. Lipids 112 (2001), 31–39.
    • (2001) Chem. Phys. Lipids , vol.112 , pp. 31-39
    • Smondyrev, A.M.1    Berkowitz, M.L.2
  • 229
    • 21444455252 scopus 로고    scopus 로고
    • Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins—activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress
    • Soccio, R.E., Adams, R.M., Maxwell, K.N., Breslow, J.L., Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins—activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress. J. Biol. Chem. 280 (2005), 19410–19418.
    • (2005) J. Biol. Chem. , vol.280 , pp. 19410-19418
    • Soccio, R.E.1    Adams, R.M.2    Maxwell, K.N.3    Breslow, J.L.4
  • 230
    • 65649083410 scopus 로고    scopus 로고
    • Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry
    • Sottero, B., Gamba, P., Gargiulo, S., Leonarduzzi, G., Poli, G., Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry. Curr. Med. Chem. 16 (2009), 685–705.
    • (2009) Curr. Med. Chem. , vol.16 , pp. 685-705
    • Sottero, B.1    Gamba, P.2    Gargiulo, S.3    Leonarduzzi, G.4    Poli, G.5
  • 231
    • 84939580455 scopus 로고    scopus 로고
    • Postprandial dysmetabolism and oxidative stress in type 2 diabetes: pathogenetic mechanisms and therapeutic strategies
    • Sottero, B., Gargiulo, S., Russo, I., Barale, C., Poli, G., Cavalot, F., Postprandial dysmetabolism and oxidative stress in type 2 diabetes: pathogenetic mechanisms and therapeutic strategies. Med. Res. Rev. 35 (2015), 968–1031.
    • (2015) Med. Res. Rev. , vol.35 , pp. 968-1031
    • Sottero, B.1    Gargiulo, S.2    Russo, I.3    Barale, C.4    Poli, G.5    Cavalot, F.6
  • 232
    • 84883181808 scopus 로고    scopus 로고
    • Sterols and oxysterols in immune cell function
    • Spann, N.J., Glass, C.K., Sterols and oxysterols in immune cell function. Nat. Immunol. 14 (2013), 893–900.
    • (2013) Nat. Immunol. , vol.14 , pp. 893-900
    • Spann, N.J.1    Glass, C.K.2
  • 233
    • 0142105845 scopus 로고    scopus 로고
    • Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum
    • Staprans, I., Pan, X.M., Rapp, J.H., Feingold, K.R., Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum. J. Lipid Res. 44 (2003), 705–715.
    • (2003) J. Lipid Res. , vol.44 , pp. 705-715
    • Staprans, I.1    Pan, X.M.2    Rapp, J.H.3    Feingold, K.R.4
  • 234
    • 28444472110 scopus 로고    scopus 로고
    • The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis
    • Staprans, I., Pan, X.M., Rapp, J.H., Feingold, K.R., The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis. Molecular Nutrition & Food Research 49 (2005), 1075–1082.
    • (2005) Molecular Nutrition & Food Research , vol.49 , pp. 1075-1082
    • Staprans, I.1    Pan, X.M.2    Rapp, J.H.3    Feingold, K.R.4
  • 235
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • Stocker, R., Keaney, J.F., Role of oxidative modifications in atherosclerosis. Physiol. Rev. 84 (2004), 1381–1478.
    • (2004) Physiol. Rev. , vol.84 , pp. 1381-1478
    • Stocker, R.1    Keaney, J.F.2
  • 236
    • 33646147145 scopus 로고    scopus 로고
    • Phase behavior of lipid monolayers containing DPPC and cholesterol analogs
    • Stottrup, B.L., Keller, S.L., Phase behavior of lipid monolayers containing DPPC and cholesterol analogs. Biophys. J. 90 (2006), 3176–3183.
    • (2006) Biophys. J. , vol.90 , pp. 3176-3183
    • Stottrup, B.L.1    Keller, S.L.2
  • 237
    • 84907472506 scopus 로고    scopus 로고
    • Comparison of cholesterol and 25-Hydroxycholesterol in phase-Separated langmuir monolayers at the air-Water interface
    • Stottrup, B.L., Hernandez-Balderrama, L.H., Kunz, J.C., Nguyen, A.H., Sonquist, B.J., Comparison of cholesterol and 25-Hydroxycholesterol in phase-Separated langmuir monolayers at the air-Water interface. J. Phys. Chem. B 118 (2014), 11231–11237.
    • (2014) J. Phys. Chem. B , vol.118 , pp. 11231-11237
    • Stottrup, B.L.1    Hernandez-Balderrama, L.H.2    Kunz, J.C.3    Nguyen, A.H.4    Sonquist, B.J.5
  • 238
    • 0001253053 scopus 로고
    • Oxygen permeability of phosphatidylcholine cholesterol membranes
    • Subczynski, W.K., Hyde, J.S., Kusumi, A., Oxygen permeability of phosphatidylcholine cholesterol membranes. Proc. Natl. Acad. Sci. U.S.A. 86 (1989), 4474–4478.
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 4474-4478
    • Subczynski, W.K.1    Hyde, J.S.2    Kusumi, A.3
  • 239
    • 0028341889 scopus 로고
    • Hydrophobic barriers of lipid bilayer-membranes formed by reduction of water penetration by alkyl chain unsaturation and cholesterol
    • Subczynski, W.K., Wisniewska, A., Yin, J.J., Hyde, J.S., Kusumi, A., Hydrophobic barriers of lipid bilayer-membranes formed by reduction of water penetration by alkyl chain unsaturation and cholesterol. Biochemistry 33 (1994), 7670–7681.
    • (1994) Biochemistry , vol.33 , pp. 7670-7681
    • Subczynski, W.K.1    Wisniewska, A.2    Yin, J.J.3    Hyde, J.S.4    Kusumi, A.5
  • 240
    • 34249861927 scopus 로고    scopus 로고
    • Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: insig renders sorting signal in Scap inaccessible to COPII proteins
    • Sun, L.-P., Seemann, J., Goldstein, J.L., Brown, M.S., Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: insig renders sorting signal in Scap inaccessible to COPII proteins. Proc. Natl. Acad. Sci. U.S.A. 104 (2007), 6519–6526.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 6519-6526
    • Sun, L.-P.1    Seemann, J.2    Goldstein, J.L.3    Brown, M.S.4
  • 241
    • 0036790522 scopus 로고    scopus 로고
    • Regulation and mechanisms of macrophage cholesterol efflux
    • Tall, A.R., Costet, P., Wang, N., Regulation and mechanisms of macrophage cholesterol efflux. J. Clin. Invest. 110 (2002), 899–904.
    • (2002) J. Clin. Invest. , vol.110 , pp. 899-904
    • Tall, A.R.1    Costet, P.2    Wang, N.3
  • 242
    • 84941662537 scopus 로고    scopus 로고
    • Reduced condensing and ordering effects by 7-Ketocholesterol and 5 beta,6 beta-Epoxycholesterol on DPPC monolayers
    • Telesford, D.-M., Verreault, D., Reick-Mitrisin, V., Allen, H.C., Reduced condensing and ordering effects by 7-Ketocholesterol and 5 beta,6 beta-Epoxycholesterol on DPPC monolayers. Langmuir 31 (2015), 9859–9869.
    • (2015) Langmuir , vol.31 , pp. 9859-9869
    • Telesford, D.-M.1    Verreault, D.2    Reick-Mitrisin, V.3    Allen, H.C.4
  • 243
    • 34248186478 scopus 로고    scopus 로고
    • 24S-hydroxycholesterol in relation to disease manifestations of acute experimental autoimmune encephalomyelitis
    • Teunissen, C.E., Floris, S., Sonke, M., Dijkstra, C.D., De Vries, H.E., Lutjohann, D., 24S-hydroxycholesterol in relation to disease manifestations of acute experimental autoimmune encephalomyelitis. J. Neurosci. Res. 85 (2007), 1499–1505.
    • (2007) J. Neurosci. Res. , vol.85 , pp. 1499-1505
    • Teunissen, C.E.1    Floris, S.2    Sonke, M.3    Dijkstra, C.D.4    De Vries, H.E.5    Lutjohann, D.6
  • 244
    • 0023044208 scopus 로고
    • Membrane properties of oxysterols. Interfacial orientation: influence on membrane permeability and redistribution between membranes
    • Theunissen, J.J.H., Jackson, R.L., Kempen, H.J.M., Demel, R.A., Membrane properties of oxysterols. Interfacial orientation: influence on membrane permeability and redistribution between membranes. Biochimica et Biophysica Acta (BBA) Biomembranes 860 (1986), 66–74.
    • (1986) Biochimica et Biophysica Acta (BBA) Biomembranes , vol.860 , pp. 66-74
    • Theunissen, J.J.H.1    Jackson, R.L.2    Kempen, H.J.M.3    Demel, R.A.4
  • 245
    • 84876368682 scopus 로고    scopus 로고
    • Cytotoxic effects of secosterols and their derivatives on several cultured cells
    • Tomono, S., Yasue, Y., Miyoshi, N., Ohshima, H., Cytotoxic effects of secosterols and their derivatives on several cultured cells. Biosci., Biotechnol., Biochem. 77 (2013), 651–653.
    • (2013) Biosci., Biotechnol., Biochem. , vol.77 , pp. 651-653
    • Tomono, S.1    Yasue, Y.2    Miyoshi, N.3    Ohshima, H.4
  • 246
    • 0037503924 scopus 로고    scopus 로고
    • Liver X receptor signaling pathways in cardiovascular disease
    • Tontonoz, P., Mangelsdorf, D.J., Liver X receptor signaling pathways in cardiovascular disease. Mol. Endocrinol. 17 (2003), 985–993.
    • (2003) Mol. Endocrinol. , vol.17 , pp. 985-993
    • Tontonoz, P.1    Mangelsdorf, D.J.2
  • 248
    • 84904043004 scopus 로고    scopus 로고
    • The cholesterol metabolite 27-Hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha
    • Umetani, M., Ghosh, P., Ishikawa, T., Umetani, J., Ahmed, M., Mineo, C., Shaul, P.W., The cholesterol metabolite 27-Hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha. Cell Metab. 20 (2014), 172–182.
    • (2014) Cell Metab. , vol.20 , pp. 172-182
    • Umetani, M.1    Ghosh, P.2    Ishikawa, T.3    Umetani, J.4    Ahmed, M.5    Mineo, C.6    Shaul, P.W.7
  • 249
    • 67349159434 scopus 로고    scopus 로고
    • Cytotoxic effects of oxysterols associated with human diseases: induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis
    • Vejux, A., Lizard, G., Cytotoxic effects of oxysterols associated with human diseases: induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis. Mol. Aspects Med. 30 (2009), 153–170.
    • (2009) Mol. Aspects Med. , vol.30 , pp. 153-170
    • Vejux, A.1    Lizard, G.2
  • 250
    • 0030001320 scopus 로고    scopus 로고
    • Physical effects of biologically formed cholesterol oxidation products on lipid membranes investigated with fluorescence depolarization spectroscopy and electron spin resonance
    • Verhagen, J.C.D., terBraake, P., Teunissen, J., vanGinkel, G., Sevanian, A., Physical effects of biologically formed cholesterol oxidation products on lipid membranes investigated with fluorescence depolarization spectroscopy and electron spin resonance. J. Lipid Res. 37 (1996), 1488–1502.
    • (1996) J. Lipid Res. , vol.37 , pp. 1488-1502
    • Verhagen, J.C.D.1    terBraake, P.2    Teunissen, J.3    vanGinkel, G.4    Sevanian, A.5
  • 251
    • 0020634542 scopus 로고
    • Chain-length dependent modification of lipid organization by low-levels of 25-hydroxycholesterol and 25-hydroxycholecalciferol—a laser raman-study
    • Verma, S.P., Philippot, J.R., Wallach, D.F.H., Chain-length dependent modification of lipid organization by low-levels of 25-hydroxycholesterol and 25-hydroxycholecalciferol—a laser raman-study. Biochemistry 22 (1983), 4587–4591.
    • (1983) Biochemistry , vol.22 , pp. 4587-4591
    • Verma, S.P.1    Philippot, J.R.2    Wallach, D.F.H.3
  • 253
    • 0035807762 scopus 로고    scopus 로고
    • Spontaneous intermembrane transfer of various cholesterol-derived hydroperoxide species: kinetic studies with model membranes and cells
    • Vila, A., Korytowski, W., Girotti, A.W., Spontaneous intermembrane transfer of various cholesterol-derived hydroperoxide species: kinetic studies with model membranes and cells. Biochemistry 40 (2001), 14715–14726.
    • (2001) Biochemistry , vol.40 , pp. 14715-14726
    • Vila, A.1    Korytowski, W.2    Girotti, A.W.3
  • 254
    • 4744363666 scopus 로고    scopus 로고
    • Sterol carrier protein-2-facilitated intermembrane transfer of cholesterol- and phospholipid-derived hydroperoxides
    • Vila, A., Levchenko, V.V., Korytowski, W., Girotti, A.W., Sterol carrier protein-2-facilitated intermembrane transfer of cholesterol- and phospholipid-derived hydroperoxides. Biochemistry 43 (2004), 12592–12605.
    • (2004) Biochemistry , vol.43 , pp. 12592-12605
    • Vila, A.1    Levchenko, V.V.2    Korytowski, W.3    Girotti, A.W.4
  • 255
    • 0021114836 scopus 로고
    • Steroid-lipid interactions in sonicated dipalmitoyl phosphatidyl choline vesicles: a steady-state and time-resolved fluorescence anisotropy study with all trans-1,6-diphenyl-1,3,5-hexatriene as probe
    • Vincent, M., Gallay, J., Steroid-lipid interactions in sonicated dipalmitoyl phosphatidyl choline vesicles: a steady-state and time-resolved fluorescence anisotropy study with all trans-1,6-diphenyl-1,3,5-hexatriene as probe. Biochem. Biophys. Res. Commun. 113 (1983), 799–810.
    • (1983) Biochem. Biophys. Res. Commun. , vol.113 , pp. 799-810
    • Vincent, M.1    Gallay, J.2
  • 256
    • 0025128695 scopus 로고
    • Phase-equilibria of cholesterol dipalmitoylphosphatidylcholine mixtures—h-2 nuclear magnetic-resonance and differential scanning calorimetry
    • Vist, M.R., Davis, J.H., Phase-equilibria of cholesterol dipalmitoylphosphatidylcholine mixtures—h-2 nuclear magnetic-resonance and differential scanning calorimetry. Biochemistry 29 (1990), 451–464.
    • (1990) Biochemistry , vol.29 , pp. 451-464
    • Vist, M.R.1    Davis, J.H.2
  • 258
    • 31544433931 scopus 로고    scopus 로고
    • A product of ozonolysis of cholesterol alters the biophysical properties of phosphatidylethanolamine membranes
    • Wachtel, E., Bach, D., Epand, R.F., Tishbee, A., Epand, R.M., A product of ozonolysis of cholesterol alters the biophysical properties of phosphatidylethanolamine membranes. Biochemistry 45 (2006), 1345–1351.
    • (2006) Biochemistry , vol.45 , pp. 1345-1351
    • Wachtel, E.1    Bach, D.2    Epand, R.F.3    Tishbee, A.4    Epand, R.M.5
  • 259
    • 57349121076 scopus 로고    scopus 로고
    • 7-Oxysterols modulate glucocorticoid activity in adipocytes through competition for 11β-hydroxysteroid dehydrogenase type
    • Wamil, M., Andrew, R., Chapman, K.E., Street, J., Morton, N.M., Seckl, J.R., 7-Oxysterols modulate glucocorticoid activity in adipocytes through competition for 11β-hydroxysteroid dehydrogenase type. Endocrinology 149 (2008), 5909–5918.
    • (2008) Endocrinology , vol.149 , pp. 5909-5918
    • Wamil, M.1    Andrew, R.2    Chapman, K.E.3    Street, J.4    Morton, N.M.5    Seckl, J.R.6
  • 260
    • 0942290630 scopus 로고    scopus 로고
    • Relationship between sterol/steroid structure and participation in ordered lipid domains (lipid rafts): Implications for lipid raft structure and function
    • Wang, J.W., Megha, London, E., Relationship between sterol/steroid structure and participation in ordered lipid domains (lipid rafts): Implications for lipid raft structure and function. Biochemistry 43 (2004), 1010–1018.
    • (2004) Biochemistry , vol.43 , pp. 1010-1018
    • Wang, J.W.1    Megha2    London, E.3
  • 261
    • 14644391519 scopus 로고    scopus 로고
    • OSBP is a cholesterol-regrulated scaffolding protein in control of ERK1/2 activation
    • Wang, P.Y., Weng, F., Anderson, R.G.W., OSBP is a cholesterol-regrulated scaffolding protein in control of ERK1/2 activation. Science 307 (2005), 1472–1476.
    • (2005) Science , vol.307 , pp. 1472-1476
    • Wang, P.Y.1    Weng, F.2    Anderson, R.G.W.3
  • 263
    • 0344198165 scopus 로고    scopus 로고
    • Steroid structural requirements for stabilizing or disrupting lipid domains
    • Wenz, J.J., Barrantes, F.J., Steroid structural requirements for stabilizing or disrupting lipid domains. Biochemistry 42 (2003), 14267–14276.
    • (2003) Biochemistry , vol.42 , pp. 14267-14276
    • Wenz, J.J.1    Barrantes, F.J.2
  • 264
    • 84938912883 scopus 로고    scopus 로고
    • Molecular properties of steroids involved in their effects on the biophysical state of membranes
    • Wenz, J.J., Molecular properties of steroids involved in their effects on the biophysical state of membranes. Biochimica Et Biophysica Acta-Biomembranes 1848 (2015), 2448–2459.
    • (2015) Biochimica Et Biophysica Acta-Biomembranes , vol.1848 , pp. 2448-2459
    • Wenz, J.J.1
  • 265
    • 0032769495 scopus 로고    scopus 로고
    • The role of oxysterols in cholesterol homeostasis
    • Wolf, G., The role of oxysterols in cholesterol homeostasis. Nutr. Rev. 57 (1999), 196–198.
    • (1999) Nutr. Rev. , vol.57 , pp. 196-198
    • Wolf, G.1
  • 266
    • 0028827485 scopus 로고
    • Phospholipid surface-density determines the partitioning and permeability of acetic-acid in dmpc-cholesterol bilayers
    • Xiang, T.X., Anderson, B.D., Phospholipid surface-density determines the partitioning and permeability of acetic-acid in dmpc-cholesterol bilayers. J. Membr. Biol. 148 (1995), 157–167.
    • (1995) J. Membr. Biol. , vol.148 , pp. 157-167
    • Xiang, T.X.1    Anderson, B.D.2
  • 267
    • 0032489637 scopus 로고    scopus 로고
    • Phase structures of binary lipid bilayers as revealed by permeability of small molecules
    • Xiang, T.X., Anderson, B.D., Phase structures of binary lipid bilayers as revealed by permeability of small molecules. Biochimica Et Biophysica Acta-Biomembranes 1370 (1998), 64–76.
    • (1998) Biochimica Et Biophysica Acta-Biomembranes , vol.1370 , pp. 64-76
    • Xiang, T.X.1    Anderson, B.D.2
  • 268
    • 84930908151 scopus 로고    scopus 로고
    • Identification of cholesterol 25-Hydroxylase as a novel host restriction factor and a part of the primary innate immune responses against hepatitis C virus infection
    • Xiang, Y., Tang, J.J., Tao, W.Y., Cao, X.Z., Song, B.L., Zhong, J., Identification of cholesterol 25-Hydroxylase as a novel host restriction factor and a part of the primary innate immune responses against hepatitis C virus infection. J. Virol. 89 (2015), 6805–6816.
    • (2015) J. Virol. , vol.89 , pp. 6805-6816
    • Xiang, Y.1    Tang, J.J.2    Tao, W.Y.3    Cao, X.Z.4    Song, B.L.5    Zhong, J.6
  • 269
    • 0034620610 scopus 로고    scopus 로고
    • The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation
    • Xu, X.L., London, E., The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation. Biochemistry 39 (2000), 843–849.
    • (2000) Biochemistry , vol.39 , pp. 843-849
    • Xu, X.L.1    London, E.2
  • 270
    • 34548456890 scopus 로고    scopus 로고
    • 22R-Hydroxycholesterol induces differentiation of human NT2 precursor (Ntera2/D1 teratocarcinoma) cells
    • Yao, Z.X., Han, Z., Xu, J., Greeson, J., Lecanu, L., Papadopoulos, V., 22R-Hydroxycholesterol induces differentiation of human NT2 precursor (Ntera2/D1 teratocarcinoma) cells. Neuroscience 148 (2007), 441–453.
    • (2007) Neuroscience , vol.148 , pp. 441-453
    • Yao, Z.X.1    Han, Z.2    Xu, J.3    Greeson, J.4    Lecanu, L.5    Papadopoulos, V.6
  • 272
    • 33644651160 scopus 로고    scopus 로고
    • Liver X receptors as integrators of metabolic and inflammatory signaling
    • Zelcer, N., Tontonoz, P., Liver X receptors as integrators of metabolic and inflammatory signaling. J. Clin. Invest. 116 (2006), 607–614.
    • (2006) J. Clin. Invest. , vol.116 , pp. 607-614
    • Zelcer, N.1    Tontonoz, P.2
  • 273
    • 0038175518 scopus 로고    scopus 로고
    • Cholesterol is superior to 7-Ketocholesterol or 7 alpha-hydroxycholesterol as an allosteric activator for acyl-coenzyme A: cholesterol acyltransferase 1
    • Zhang, Y., Yu, C.J., Liu, J., Spencer, T.A., Chang, C.C.Y., Chang, T.Y., Cholesterol is superior to 7-Ketocholesterol or 7 alpha-hydroxycholesterol as an allosteric activator for acyl-coenzyme A: cholesterol acyltransferase 1. J. Biol. Chem. 278 (2003), 11642–11647.
    • (2003) J. Biol. Chem. , vol.278 , pp. 11642-11647
    • Zhang, Y.1    Yu, C.J.2    Liu, J.3    Spencer, T.A.4    Chang, C.C.Y.5    Chang, T.Y.6
  • 274
    • 84884314618 scopus 로고    scopus 로고
    • Oxysterols in cancer cell proliferation and death
    • de Weille, J., Fabre, C., Bakalara, N., Oxysterols in cancer cell proliferation and death. Biochem. Pharmacol. 86 (2013), 154–160.
    • (2013) Biochem. Pharmacol. , vol.86 , pp. 154-160
    • de Weille, J.1    Fabre, C.2    Bakalara, N.3
  • 275
    • 0024382391 scopus 로고
    • Transfer of cholesterol and oxysterol derivatives by the nonspecific lipid transfer protein (sterol carrier protein 2): a study on its mode of action
    • van Amerongen, A., Demel, R.A., Westerman, J., Wirtz, K.W.A., Transfer of cholesterol and oxysterol derivatives by the nonspecific lipid transfer protein (sterol carrier protein 2): a study on its mode of action. Biochimica et Biophysica Acta (BBA) − Lipids and Lipid Metabolism 1004 (1989), 36–43.
    • (1989) Biochimica et Biophysica Acta (BBA) − Lipids and Lipid Metabolism , vol.1004 , pp. 36-43
    • van Amerongen, A.1    Demel, R.A.2    Westerman, J.3    Wirtz, K.W.A.4
  • 277
    • 0032872780 scopus 로고    scopus 로고
    • The macrophage in atherosclerosis: modulation of cell function by sterols
    • van Reyk, D.M., Jessup, W., The macrophage in atherosclerosis: modulation of cell function by sterols. J. Leukoc. Biol. 66 (1999), 557–561.
    • (1999) J. Leukoc. Biol. , vol.66 , pp. 557-561
    • van Reyk, D.M.1    Jessup, W.2
  • 278
    • 33846084357 scopus 로고    scopus 로고
    • Oxysterols in biological systems: sources, metabolism and pathophysiological relevance
    • van Reyk, D.M., Brown, A.J., Hult'en, L.M., Dean, R.T., Jessup, W., Oxysterols in biological systems: sources, metabolism and pathophysiological relevance. Redox Rep. 11 (2006), 255–262.
    • (2006) Redox Rep. , vol.11 , pp. 255-262
    • van Reyk, D.M.1    Brown, A.J.2    Hult'en, L.M.3    Dean, R.T.4    Jessup, W.5
  • 279
    • 0035492820 scopus 로고    scopus 로고
    • Identification and quantification of cholesterol oxidation products in canned tuna
    • Zunin, P., Boggia, R., Evangelisti, F., Identification and quantification of cholesterol oxidation products in canned tuna. J. Am. Oil Chem. Soc. 78 (2001), 1037–1040.
    • (2001) J. Am. Oil Chem. Soc. , vol.78 , pp. 1037-1040
    • Zunin, P.1    Boggia, R.2    Evangelisti, F.3


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