Cholesterol under oxidative stress - How lipid membranes sense oxidation as cholesterol is being replaced by oxysterols

Free Radical Biology and Medicine

Volumn 84, Issue , 2015, Pages 30-41

  Kulig, Waldemar ^a   Olzyńska, Agnieszka ^b   Jurkiewicz, Piotr ^b   Kantola, Anu M ^c   Komulainen, Sanna ^c   Manna, Moutusi ^a   Pourmousa, Mohsen ^a   Vazdar, Mario ^a,d   Cwiklik, Lukasz ^b,e   Rog, Tomasz ^a   Khelashvili, George ^f   Harries, Daniel ^g   Telkki, Ville Veikko ^c   Hof, Martin ^b   Vattulainen, Ilpo ^a,h   Jungwirth, Pavel ^a,e  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b J HEYROVSKÝ INSTITUTE OF PHYSICAL CHEMISTRY   (Czech Republic)

^c UNIVERSITY OF OULU   (Finland)

^d RUDER BO KOVI INSTITUTE   (Croatia)

^e INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

^g HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^h UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

DPH anisotropy; Laurdan fluorescence; Liposomes; Molecular dynamics simulations; NMR measurements; Oxysterols; Phospholipid bilayers; Tilt modulus

Indexed keywords

2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; 24 HYDROXYCHOLESTEROL; 25 CHOLESTENOIC ACID; 25 HYDROXYCHOLESTEROL; 26 HYDROXYCHOLESTEROL; 3BETA,5ALPHA,6BETA TRIHYDROXYCHOLESTANE; 4BETA HYDROXYCHOLESTEROL; 7 OXOCHOLESTEROL; 7ALPHA HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; CHOLESTEROL; FREE RADICAL; OXYSTEROL; STEROL; UNCLASSIFIED DRUG; 1-PALMITOYL-2-OLEOYLPHOSPHATIDYLCHOLINE; CHOLESTEROL DERIVATIVE; LIPID BILAYER; PHOSPHATIDYLCHOLINE;

ARTICLE; BILAYER MEMBRANE; BIOCHEMISTRY; CELL FUNCTION; CHEMICAL STRUCTURE; ENZYMATIC DEGRADATION; FLUORESCENCE SPECTROSCOPY; HUMAN; LIGHT SCATTERING; LIPID BILAYER; LIPID MEMBRANE; LIPID OXIDATION; LIPID VESICLE; MEMBRANE PERMEABILITY; MEMBRANE STRUCTURE; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXIDATIVE STRESS; PHOSPHOLIPID BILAYER; PHOSPHOLIPID MEMBRANE; PHYSICAL PARAMETERS; PRIORITY JOURNAL; REACTION ANALYSIS; SIGNAL TRANSDUCTION; STEADY STATE; STRUCTURE ANALYSIS; CELL MEMBRANE; CHEMISTRY; FLUORESCENCE POLARIZATION;

CELL MEMBRANE; FLUORESCENCE POLARIZATION; HYDROXYCHOLESTEROLS; LIPID BILAYERS; MOLECULAR DYNAMICS SIMULATION; OXIDATIVE STRESS; PHOSPHATIDYLCHOLINES;

EID: 84928530055     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.03.006     Document Type: Article

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