7-Ketocholesterol and 5,6-secosterol induce human endothelial cell dysfunction by differential mechanisms

Steroids

Volumn 99, Issue PB, 2015, Pages 204-211

  Luchetti, Francesca ^a   Canonico, Barbara ^a   Cesarini, Erica ^a   Betti, Michele ^a   Galluzzi, Luca ^a   Galli, Laura ^a   Tippins, John ^b   Zerbinati, Chiara ^c   Papa, Stefano ^a   Iuliano, Luigi ^c  

^a UNIVERSITY OF URBINO   (Italy)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

5,6 Secosterol; 7 Ketocholesterol; Apoptosis; Endothelial dysfunction; HUVEC; Oxysterols

Indexed keywords

5,6 SECOSTEROL; 7 OXOCHOLESTEROL; PROTEIN KINASE C; PROTEIN P53; STEROL DERIVATIVE; UNCLASSIFIED DRUG; 5,6-SECOSTEROL; 7-KETOCHOLESTEROL; CARDIOLIPIN; CHOLESTEROL DERIVATIVE; LIPOCORTIN 5; PROPIDIUM IODIDE; STEROL;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LYSOSOME; MITOCHONDRION; UPREGULATION; VASCULAR RING; VASODILATATION; ANIMAL; AORTA; CYTOLOGY; DRUG EFFECTS; IN VITRO STUDY; INTRACELLULAR MEMBRANE; LIPID METABOLISM; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; STAINING; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; ANNEXIN A5; AORTA; APOPTOSIS; CARDIOLIPINS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IN VITRO TECHNIQUES; INTRACELLULAR MEMBRANES; KETOCHOLESTEROLS; LIPID METABOLISM; LYSOSOMES; MITOCHONDRIA; OXIDATION-REDUCTION; PROPIDIUM; RATS; SIGNAL TRANSDUCTION; STAINING AND LABELING; STEROLS; VASODILATION;

EID: 84937391210     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2015.02.008     Document Type: Article

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