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Volumn 110, Issue 7, 2002, Pages 899-904

Regulation and mechanisms of macrophage cholesterol efflux

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; CHOLESTEROL; CYCLIC AMP; HIGH DENSITY LIPOPROTEIN; MESSENGER RNA; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; TRANSCRIPTION FACTOR LXR; TRANSCRIPTION FACTOR RXR; UNCLASSIFIED DRUG;

EID: 0036790522     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI0216391     Document Type: Review
Times cited : (195)

References (49)
  • 1
    • 0031761005 scopus 로고    scopus 로고
    • The response-to-retention hypothesis of atherogenesis reinforced
    • Williams, K.J., and Tabas, I. 1998. The response-to-retention hypothesis of atherogenesis reinforced. Curr. Opin. Lipidol. 9:471-474.
    • (1998) Curr. Opin. Lipidol. , vol.9 , pp. 471-474
    • Williams, K.J.1    Tabas, I.2
  • 2
    • 0019728872 scopus 로고
    • The effects of subfractions of high density lipoprotein on cholesterol efflux from cultured fibroblasts. Regulation of low density lipoprotein receptor activity
    • Oram, J.F., Albers, J.J., Cheung, M.C., and Bierman, E.L. 1981. The effects of subfractions of high density lipoprotein on cholesterol efflux from cultured fibroblasts. Regulation of low density lipoprotein receptor activity. J. Biol. Chem. 256:8348-8356.
    • (1981) J. Biol. Chem. , vol.256 , pp. 8348-8356
    • Oram, J.F.1    Albers, J.J.2    Cheung, M.C.3    Bierman, E.L.4
  • 3
    • 0025728398 scopus 로고
    • Interaction of free apolipoproteins with macrophages. Formation of high density lipoprotein-like lipoproteins and reduction of cellular cholesterol
    • Hara, H., and Yokoyama, S. 1991. Interaction of free apolipoproteins with macrophages. Formation of high density lipoprotein-like lipoproteins and reduction of cellular cholesterol. J. Biol. Chem. 266:3080-3086.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3080-3086
    • Hara, H.1    Yokoyama, S.2
  • 4
    • 0025902231 scopus 로고
    • Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI
    • Rubin, E.M., Krauss, R.M., Spangler, E.A., Verstuyft, J.G., and Clift, S.M. 1991. Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI. Nature. 353:265-267.
    • (1991) Nature , vol.353 , pp. 265-267
    • Rubin, E.M.1    Krauss, R.M.2    Spangler, E.A.3    Verstuyft, J.G.4    Clift, S.M.5
  • 5
    • 0028025262 scopus 로고
    • Human apolipoprotein A·I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse
    • Plump, A.S., Scott, C.J., and Breslow, J.L. 1994. Human apolipoprotein A·I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse. Proc. Natl. Acad. Sci. USA. 91:9607-9611.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9607-9611
    • Plump, A.S.1    Scott, C.J.2    Breslow, J.L.3
  • 6
    • 0029082507 scopus 로고
    • Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier disease
    • Francis, G.A., Knopp, R.H., and Oram, J.F. 1995. Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier disease. J. Clin. Invest. 96:78-87.
    • (1995) J. Clin. Invest. , vol.96 , pp. 78-87
    • Francis, G.A.1    Knopp, R.H.2    Oram, J.F.3
  • 7
    • 0035095882 scopus 로고    scopus 로고
    • Localization of human ATP-binding cassette transporter 1(ABC1) in normal and atherosclerotic tissues
    • Lawn, R.M., Wade, D.P., Couse, T.L., and Wilcox, J.N. 2001. Localization of human ATP-binding cassette transporter 1(ABC1) in normal and atherosclerotic tissues. Arterioscler. Thromb. Vasc. Biol. 21:378-385.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 378-385
    • Lawn, R.M.1    Wade, D.P.2    Couse, T.L.3    Wilcox, J.N.4
  • 8
    • 0033515841 scopus 로고    scopus 로고
    • Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): Evidence for sterol-dependent regulation in macrophages
    • Langmann, T., et al. 1999. Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages. Biochem. Biophys. Res. Commun. 257:29-33.
    • (1999) Biochem. Biophys. Res. Commun. , vol.257 , pp. 29-33
    • Langmann, T.1
  • 9
    • 0035914330 scopus 로고    scopus 로고
    • 27-Hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells
    • Fu, X., et al. 2001. 27-Hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J. Biol. Chem. 276:38378-38387.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38378-38387
    • Fu, X.1
  • 10
    • 0036736781 scopus 로고    scopus 로고
    • Do oxysterols control cholesterol homeostasis?
    • doi: 10.1172/JCI200216388
    • Björkhem, I. 2002. Do oxysterols control cholesterol homeostasis? J. Clin. Invest. 110:725-730. doi: 10.1172/JCI200216388.
    • (2002) J. Clin. Invest. , vol.110 , pp. 725-730
    • Björkhem, I.1
  • 11
    • 0035966125 scopus 로고    scopus 로고
    • Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate
    • Gan, X., et al. 2001. Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate. J. Biol. Chem. 276:48702-48708.
    • (2001) J. Biol. Chem. , vol.276 , pp. 48702-48708
    • Gan, X.1
  • 12
    • 0036289296 scopus 로고    scopus 로고
    • Cyclic AMP-specific phosphodiesterase 4 inhibitors promote ABCA1 expression and cholesterol efflux
    • Lin, G., and Bornfeldt, K.E. 2002. Cyclic AMP-specific phosphodiesterase 4 inhibitors promote ABCA1 expression and cholesterol efflux. Biochem. Biophys. Res. Commun. 290:663-669.
    • (2002) Biochem. Biophys. Res. Commun. , vol.290 , pp. 663-669
    • Lin, G.1    Bornfeldt, K.E.2
  • 13
    • 0034080596 scopus 로고    scopus 로고
    • Interferon-gamma induces downregulation of Tangier disease gene (ATP-binding-cassette transporter 1) in macrophage-derived foam cells
    • Panousis, C.G., and Zuckerman, S.H. 2000. Interferon-gamma induces downregulation of Tangier disease gene (ATP-binding-cassette transporter 1) in macrophage-derived foam cells. Arterioscler. Thromb. Vasc. Biol. 20:1565-1571.
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 1565-1571
    • Panousis, C.G.1    Zuckerman, S.H.2
  • 14
    • 17744376173 scopus 로고    scopus 로고
    • A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
    • Chawla, A., et al. 2001. A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol. Cell. 7:161-171.
    • (2001) Mol. Cell , vol.7 , pp. 161-171
    • Chawla, A.1
  • 15
    • 0036205326 scopus 로고    scopus 로고
    • Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux
    • Akiyama, T.E., et al. 2002. Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux. Mol. Cell. Biol. 22:2607-2619.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2607-2619
    • Akiyama, T.E.1
  • 16
    • 0035957006 scopus 로고    scopus 로고
    • Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor
    • Claudel, T., et al. 2001. Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor. Proc. Natl. Acad. Sci. USA. 98:2610-2615.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2610-2615
    • Claudel, T.1
  • 17
    • 0035942162 scopus 로고    scopus 로고
    • A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport
    • Oliver, W.R., Jr., et al. 2001. A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport. Proc. Natl. Acad. Sci. USA. 98:5306-5311.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5306-5311
    • Oliver W.R., Jr.1
  • 18
    • 0035932990 scopus 로고    scopus 로고
    • Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR
    • Ou, J., et al. 2001. Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR. Proc. Natl. Acad. Sci. USA. 98:6027-6032.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6027-6032
    • Ou, J.1
  • 19
    • 0037085289 scopus 로고    scopus 로고
    • Unsaturated fatty acids inhibit cholesterol efflux from macrophages by increasing degradation of ATP-binding cassette transporter A1
    • Wang, Y., and Oram, J.F. 2002. Unsaturated fatty acids inhibit cholesterol efflux from macrophages by increasing degradation of ATP-binding cassette transporter A1. J. Biol. Chem. 277:5692-5697.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5692-5697
    • Wang, Y.1    Oram, J.F.2
  • 20
    • 0037151002 scopus 로고    scopus 로고
    • Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation
    • Arakawa, R., and Yokoyama, S. 2002. Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation. J. Biol. Chem. 277:22426-22429.
    • (2002) J. Biol. Chem. , vol.277 , pp. 22426-22429
    • Arakawa, R.1    Yokoyama, S.2
  • 21
    • 0032945240 scopus 로고    scopus 로고
    • Cell cholesterol efflux: Integration of old and new observations provides new insights
    • Rothblat, G.H., et al. 1999. Cell cholesterol efflux: integration of old and new observations provides new insights. J. Lipid Res. 40:781-796.
    • (1999) J. Lipid Res. , vol.40 , pp. 781-796
    • Rothblat, G.H.1
  • 22
    • 0030046797 scopus 로고    scopus 로고
    • Identification of scavenger receptor SR-BI as a high density lipoprotein receptor
    • Acton, S., et al. 1996. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science. 271:518-520.
    • (1996) Science , vol.271 , pp. 518-520
    • Acton, S.1
  • 23
    • 0030868610 scopus 로고    scopus 로고
    • Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux
    • Ji, Y., et al. 1997. Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux. J. Biol. Chem. 272:20982-20985.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20982-20985
    • Ji, Y.1
  • 24
    • 0034730747 scopus 로고    scopus 로고
    • Scavenger receptor class B, type I-mediated [3H]cholesterol efflux to high and low density lipoproreins is dependent on lipoprotein binding to the receptor
    • Gu, X., Kozarsky, K., and Krieger, M. 2000. Scavenger receptor class B, type I-mediated [3H]cholesterol efflux to high and low density lipoproreins is dependent on lipoprotein binding to the receptor. J. Biol. Chem. 275:29993-30001.
    • (2000) J. Biol. Chem. , vol.275 , pp. 29993-30001
    • Gu, X.1    Kozarsky, K.2    Krieger, M.3
  • 25
    • 0034693064 scopus 로고    scopus 로고
    • Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1
    • Wang, N., Silver, D.L., Costet, P., and Tall, A.R. 2000. Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1. J. Biol. Chem. 275:33053-33058.
    • (2000) J. Biol. Chem. , vol.275 , pp. 33053-33058
    • Wang, N.1    Silver, D.L.2    Costet, P.3    Tall, A.R.4
  • 26
    • 0023663531 scopus 로고
    • Mechanisms and consequences of cellular cholesterol exchange and transfer
    • Phillips, M.C., Johnson, W.J., and Rothblat, G.H. 1987. Mechanisms and consequences of cellular cholesterol exchange and transfer. Biochim. Biophys. Acta. 906:223-276.
    • (1987) Biochim. Biophys. Acta , vol.906 , pp. 223-276
    • Phillips, M.C.1    Johnson, W.J.2    Rothblat, G.H.3
  • 27
    • 0034647918 scopus 로고    scopus 로고
    • Binding of high density lipoprotein (HDL) and discoidal reconstituted HDL to the HDL receptor scavenger receptor class B type I. Effect of lipid association and APOA-I mutations on receptor binding
    • Liadaki, K.N., et al. 2000. Binding of high density lipoprotein (HDL) and discoidal reconstituted HDL to the HDL receptor scavenger receptor class B type I. Effect of lipid association and APOA-I mutations on receptor binding. J. Biol. Chem. 275:21262-21271.
    • (2000) J. Biol. Chem. , vol.275 , pp. 21262-21271
    • Liadaki, K.N.1
  • 28
    • 0035968199 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein
    • Wang, N., Silver, D.L., Thiele, C., and Tall, A.R. 2001. ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein. J. Biol. Chem. 276:23742-23747.
    • (2001) J. Biol. Chem. , vol.276 , pp. 23742-23747
    • Wang, N.1    Silver, D.L.2    Thiele, C.3    Tall, A.R.4
  • 30
    • 0035968213 scopus 로고    scopus 로고
    • Membrane topology of the ATP binding cassette transporter ABCR and its relationship to ABC1 and related ABCA transporters: Identification of N-linked glycosylation sites
    • Bungert, S., Molday, L.L., and Molday, R.S. 2001. Membrane topology of the ATP binding cassette transporter ABCR and its relationship to ABC1 and related ABCA transporters: identification of N-linked glycosylation sites. J. Biol. Chem. 276:23539-23546.
    • (2001) J. Biol. Chem. , vol.276 , pp. 23539-23546
    • Bungert, S.1    Molday, L.L.2    Molday, R.S.3
  • 31
    • 0034816722 scopus 로고    scopus 로고
    • Apolipoprotein specificity for lipid efflux by the human ABCA1 transporter
    • Remaley, A.T., et al. 2001. Apolipoprotein specificity for lipid efflux by the human ABCA1 transporter. Biochem. Biophys. Res. Commun. 280:818-823.
    • (2001) Biochem. Biophys. Res. Commun. , vol.280 , pp. 818-823
    • Remaley, A.T.1
  • 32
    • 0034602387 scopus 로고    scopus 로고
    • ABCA1 is the cAMP-inducible apolipoprorein receptor that mediates cholesterol secretion from macrophages
    • Oram, J.F., Lawn, R.M., Garvin, M.R., and Wade, D.P. 2000. ABCA1 is the cAMP-inducible apolipoprorein receptor that mediates cholesterol secretion from macrophages. J. Biol. Chem. 275:34508-34511.
    • (2000) J. Biol. Chem. , vol.275 , pp. 34508-34511
    • Oram, J.F.1    Lawn, R.M.2    Garvin, M.R.3    Wade, D.P.4
  • 33
    • 0037031835 scopus 로고    scopus 로고
    • Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I
    • Fitzgerald, M.L., et al. 2002. Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I. J. Biol. Chem. 277:33178-33187.
    • (2002) J. Biol. Chem. , vol.277 , pp. 33178-33187
    • Fitzgerald, M.L.1
  • 34
    • 0035971064 scopus 로고    scopus 로고
    • Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter
    • Chambenoit, O., et al. 2001. Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter. J. Biol. Chem. 276:9955-9960.
    • (2001) J. Biol. Chem. , vol.276 , pp. 9955-9960
    • Chambenoit, O.1
  • 35
    • 0035920220 scopus 로고    scopus 로고
    • Cellular localization and trafficking of the human ABCA1 transporter
    • Neufeld, E.B., et al. 2001. Cellular localization and trafficking of the human ABCA1 transporter. J. Biol. Chem. 276:27584-27590.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27584-27590
    • Neufeld, E.B.1
  • 36
    • 0033613166 scopus 로고    scopus 로고
    • Cholesterol efflux to apolipoprorein A1 involves endocytosis and resecretion in a calcium-dependent pathway
    • Takahashi, Y., and Smith, J.D. 1999. Cholesterol efflux to apolipoprorein A1 involves endocytosis and resecretion in a calcium-dependent pathway. Proc. Natl. Acad. Sci. USA. 96:11358-11363.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11358-11363
    • Takahashi, Y.1    Smith, J.D.2
  • 37
    • 0035941367 scopus 로고    scopus 로고
    • Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes
    • Chen, W., et al. 2001. Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes. J. Biol. Chem. 276:43564-43569.
    • (2001) J. Biol. Chem. , vol.276 , pp. 43564-43569
    • Chen, W.1
  • 38
    • 0035976969 scopus 로고    scopus 로고
    • Acid sphingomyelinase-deficient macrophages have defective cholesterol trafficking and efflux
    • Leventhal, A.R., Chen, W., Tall, A.R., and Tabas, I. 2001. Acid sphingomyelinase-deficient macrophages have defective cholesterol trafficking and efflux. J. Biol. Chem. 276:44976-44983.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44976-44983
    • Leventhal, A.R.1    Chen, W.2    Tall, A.R.3    Tabas, I.4
  • 39
    • 0036120566 scopus 로고    scopus 로고
    • Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages
    • Aiello, R.J., et al. 2002. Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages. Artorioscler. Thromb. Vasc. Biol. 22:630-637.
    • (2002) Artorioscler. Thromb. Vasc. Biol. , vol.22 , pp. 630-637
    • Aiello, R.J.1
  • 40
    • 18344364090 scopus 로고    scopus 로고
    • Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues
    • van Eck, M., et al. 2002. Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues. Proc. Natl. Acad. Sci. USA. 99:6298-6303.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6298-6303
    • Van Eck, M.1
  • 41
    • 0035947686 scopus 로고    scopus 로고
    • Regulation and activity of the human ABCA1 gene in transgenic mice
    • Cavelier, L.B., et al. 2001. Regulation and activity of the human ABCA1 gene in transgenic mice. J. Biol. Chem. 276:18046-18051.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18046-18051
    • Cavelier, L.B.1
  • 42
    • 0037039438 scopus 로고    scopus 로고
    • The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice
    • Joyce, C.W., et al. 2002. The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice. Proc. Natl. Acad. Sci. USA. 99:407-412.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 407-412
    • Joyce, C.W.1
  • 43
    • 0036301461 scopus 로고    scopus 로고
    • Increased ABCA1 activity protects against atherosclerosis
    • doi:10.1172/JCI200215748
    • Singaraja, R.R., et al. 2002. Increased ABCA1 activity protects against atherosclerosis. J. Clin. Invest. 110:35-42. doi:10.1172/JCI200215748.
    • (2002) J. Clin. Invest. , vol.110 , pp. 35-42
    • Singaraja, R.R.1
  • 44
    • 0037188553 scopus 로고    scopus 로고
    • Synthetic LXR ligand inhibits the development of atherosclerosis in mice
    • Joseph, S.B., et al. 2002. Synthetic LXR ligand inhibits the development of atherosclerosis in mice. Proc. Natl. Acad. Sci. USA. 99:7604-7609.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 7604-7609
    • Joseph, S.B.1
  • 45
    • 0018953911 scopus 로고
    • Coronary heart disease prevalence and other clinical features in familial high-density lipoprotein deficiency (Tangier disease)
    • Schaefer, E.J., Zech, L.A., Schwartz, D.E., and Brewer, H.B., Jr. 1980. Coronary heart disease prevalence and other clinical features in familial high-density lipoprotein deficiency (Tangier disease). Ann. Intern. Med. 93:261-266.
    • (1980) Ann. Intern. Med. , vol.93 , pp. 261-266
    • Schaefer, E.J.1    Zech, L.A.2    Schwartz, D.E.3    Brewer H.B., Jr.4
  • 46
    • 0037022001 scopus 로고    scopus 로고
    • Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: An observational study
    • van Dam, M.J., et al. 2002. Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study. Lancet 359:37-42.
    • (2002) Lancet , vol.359 , pp. 37-42
    • Van Dam, M.J.1
  • 47
    • 0028883354 scopus 로고
    • Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice
    • Bellosta, S., et al. 1995. Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice. J. Clin. Invest. 96:2170-2179.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2170-2179
    • Bellosta, S.1
  • 48
    • 0034669025 scopus 로고    scopus 로고
    • Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
    • Repa, J.J., et al 2000. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev. 14:2819-2830.
    • (2000) Genes Dev. , vol.14 , pp. 2819-2830
    • Repa, J.J.1
  • 49
    • 0035805621 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space
    • Fitzgerald, M.L., et al. 2001. ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space. J. Biol. Chem. 276:15137-15145.
    • (2001) J. Biol. Chem. , vol.276 , pp. 15137-15145
    • Fitzgerald, M.L.1


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