Formation of biologically active oxysterols during ozonolysis of cholesterol present in lung surfactant

Journal of Biological Chemistry

Volumn 279, Issue 25, 2004, Pages 26331-26338

  Pulfer, Melissa K ^a   Murphy, Robert C ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHOLESTEROL; MASS SPECTROMETRY; PULMONARY DISEASES; SURFACE ACTIVE AGENTS; TOXICITY;

CHEMICAL REACTIVITY; EPITHELIAL CELLS; OXYSTEROLS;

OZONIZATION;

3BETA HYDROXY 5 OXO 5,6 SECOCHOLESTAN 6 AL; 5 HYDROPEROXY BETA HOMO 6 OXA CHOLESTAN 3BETA,7ALPHA DIOL; CHOLESTAN 6 OXO 3BETA,5ALPHA DIOL; CHOLESTANETRIOL; CHOLESTEROL; CHOLESTEROL 5BETA,6BETA OXIDE; ISOPRENOID; LIPID; LUNG SURFACTANT; OXYSTEROL; OZONE; UNCLASSIFIED DRUG;

AMBIENT AIR; ARTICLE; BIOSYNTHESIS; BRONCHUS MUCOSA; CELL CULTURE; CHEMICAL REACTION; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; LUNG TOXICITY; MASS SPECTROMETRY; OZONOLYSIS; PRIORITY JOURNAL; RADIATION MONITORING; REACTION ANALYSIS; STEROL SYNTHESIS;

ANIMALS; BRONCHI; CELL SURVIVAL; CELLS, CULTURED; CHOLESTEROL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LIPID METABOLISM; LUNG; MODELS, CHEMICAL; OZONE; PULMONARY SURFACTANTS; RATS; STEROLS; TIME FACTORS;

BRONCHUS; HOMO;

EID: 2942707855     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403581200     Document Type: Article

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