메뉴 건너뛰기




Volumn 438, Issue 7068, 2005, Pages 612-621

Role of cholesterol and lipid organization in disease

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY; CELL MEMBRANES; DISEASE CONTROL; LIPIDS; METABOLISM;

EID: 28444479505     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04399     Document Type: Review
Times cited : (1075)

References (100)
  • 1
    • 7044241302 scopus 로고    scopus 로고
    • How lipids affect the activities of integral membrane proteins
    • Lee, A. G. How lipids affect the activities of integral membrane proteins. Biochim. Biophys. Acta 1666, 62-87 (2004).
    • (2004) Biochim. Biophys. Acta , vol.1666 , pp. 62-87
    • Lee, A.G.1
  • 4
    • 29144485364 scopus 로고    scopus 로고
    • Lipid segregation and IgE receptor signaling: A decade of progress
    • doi:10.1016/j.bbamcr.2005.06.007
    • Holowka, D. et al. Lipid segregation and IgE receptor signaling: A decade of progress. Biochim. Biophys. Acta doi:10.1016/j.bbamcr.2005.06.007 (2005).
    • (2005) Biochim. Biophys. Acta
    • Holowka, D.1
  • 5
    • 0035906980 scopus 로고    scopus 로고
    • Molecular medicine. The cholesterol quartet
    • Goldstein, J. L. & Brown, M. S. Molecular medicine. The cholesterol quartet. Science 292, 1310-1312 (2001).
    • (2001) Science , vol.292 , pp. 1310-1312
    • Goldstein, J.L.1    Brown, M.S.2
  • 6
    • 0001910351 scopus 로고
    • Über experimentelle cholesterinsteatose und ihre bedeutung für die einiger pathologischer prozesse
    • Anitschkow, N. & Chalatow, S. Über experimentelle cholesterinsteatose und ihre bedeutung für die einiger pathologischer prozesse. Zentralbl. Allg. Pathol. 24, 1-9 (1913).
    • (1913) Zentralbl. Allg. Pathol. , vol.24 , pp. 1-9
    • Anitschkow, N.1    Chalatow, S.2
  • 7
    • 10044283187 scopus 로고    scopus 로고
    • Cholesterol, statins and dementia
    • Wolozin, B. Cholesterol, statins and dementia. Curr. Opin. Lipidol. 15, 667-672 (2004).
    • (2004) Curr. Opin. Lipidol. , vol.15 , pp. 667-672
    • Wolozin, B.1
  • 8
    • 0030949124 scopus 로고    scopus 로고
    • Functional rafts in cell membranes
    • Simons, K. & Ikonen, E. Functional rafts in cell membranes. Nature 387, 569-572 (1997).
    • (1997) Nature , vol.387 , pp. 569-572
    • Simons, K.1    Ikonen, E.2
  • 9
    • 0344585437 scopus 로고    scopus 로고
    • Lipid rafts: Elusive or illusive?
    • Munro, S. Lipid rafts: elusive or illusive? Cell 115, 377-388 (2003).
    • (2003) Cell , vol.115 , pp. 377-388
    • Munro, S.1
  • 11
    • 0031964607 scopus 로고    scopus 로고
    • Cholesterol and sphingolipid enhance the Triton X-100 insolubility of glycosylphosphatidylinositol-anchored proteins by promoting the formation of detergent-insoluble ordered membrane domains
    • Schroeder, R. J., Ahmed, S. N., Zhu, Y., London, E. & Brown, D. A. Cholesterol and sphingolipid enhance the Triton X-100 insolubility of glycosylphosphatidylinositol-anchored proteins by promoting the formation of detergent-insoluble ordered membrane domains. J. Biol. Chem. 273, 1150-1157 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 1150-1157
    • Schroeder, R.J.1    Ahmed, S.N.2    Zhu, Y.3    London, E.4    Brown, D.A.5
  • 12
    • 7444255626 scopus 로고    scopus 로고
    • Membrane targeting of lipid modified signal transduction proteins
    • Resh, M. D. Membrane targeting of lipid modified signal transduction proteins. Subcell. Biochem. 37, 217-232 (2004).
    • (2004) Subcell. Biochem. , vol.37 , pp. 217-232
    • Resh, M.D.1
  • 13
    • 0035980238 scopus 로고    scopus 로고
    • Partitioning of lipidated peptide sequences into liquid-ordered lipid domains in model and biological membranes
    • Wang, T. Y., Leventis, R. & Silvius, J. R. Partitioning of lipidated peptide sequences into liquid-ordered lipid domains in model and biological membranes. Biochemistry 40, 13031-13040 (2001).
    • (2001) Biochemistry , vol.40 , pp. 13031-13040
    • Wang, T.Y.1    Leventis, R.2    Silvius, J.R.3
  • 14
    • 0033525077 scopus 로고    scopus 로고
    • Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated
    • Melkonian, K. A., Ostermeyer, A. G., Chen, J. Z., Roth, M. G. & Brown, D. A. Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated. J. Biol. Chem. 274, 3910-3917 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 3910-3917
    • Melkonian, K.A.1    Ostermeyer, A.G.2    Chen, J.Z.3    Roth, M.G.4    Brown, D.A.5
  • 15
    • 0027892019 scopus 로고
    • Cholesterol and the Golgi apparatus
    • Bretscher, M. S. & Munro, S. Cholesterol and the Golgi apparatus. Science 261, 1280-1281 (1993).
    • (1993) Science , vol.261 , pp. 1280-1281
    • Bretscher, M.S.1    Munro, S.2
  • 16
    • 1642570286 scopus 로고    scopus 로고
    • Modulation of the bilayer thickness of exocytic pathway membranes by membrane proteins rather than cholesterol
    • Mitra, K., Ubarretxena-Belandia, I., Taguchi, T., Warren, G. & Engelman, D. M. Modulation of the bilayer thickness of exocytic pathway membranes by membrane proteins rather than cholesterol. Proc. Natl Acad. Sci. USA 101, 4083-4038 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4083-14038
    • Mitra, K.1    Ubarretxena-Belandia, I.2    Taguchi, T.3    Warren, G.4    Engelman, D.M.5
  • 17
    • 0037562005 scopus 로고    scopus 로고
    • Membrane lipid organization is critical for human neutrophil polarization
    • Pierini, L. M. et al. Membrane lipid organization is critical for human neutrophil polarization. J. Biol. Chem. 278, 10831-10841 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 10831-10841
    • Pierini, L.M.1
  • 18
    • 14744272151 scopus 로고    scopus 로고
    • Intramembrane aspartic acid in SCAP protein governs cholesterol-induced conformational change
    • Feramisco, J. D. et al. Intramembrane aspartic acid in SCAP protein governs cholesterol-induced conformational change. Proc. Natl Acad. Sci. USA 102, 3242-3247 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 3242-3247
    • Feramisco, J.D.1
  • 19
    • 0037016677 scopus 로고    scopus 로고
    • Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle
    • Hao, M. et al. Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle. J. Biol. Chem. 277, 609-617 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 609-617
    • Hao, M.1
  • 20
    • 0036791574 scopus 로고    scopus 로고
    • Intracellular cholesterol transport
    • Maxfield, F. R. & Wustner, D. Intracellular cholesterol transport. J. Clin. Invest. 110, 891-898 (2002).
    • (2002) J. Clin. Invest. , vol.110 , pp. 891-898
    • Maxfield, F.R.1    Wustner, D.2
  • 21
    • 0038461879 scopus 로고    scopus 로고
    • Macrophage cholesterol transport: A critical player in foam cell formation
    • Vainio, S. & Ikonen, E. Macrophage cholesterol transport: a critical player in foam cell formation. Ann. Med. 35, 146-155 (2003).
    • (2003) Ann. Med. , vol.35 , pp. 146-155
    • Vainio, S.1    Ikonen, E.2
  • 23
    • 0038630960 scopus 로고    scopus 로고
    • START domain proteins and the intracellular trafficking of cholesterol in steroidogenic cells
    • Strauss, J. F., Kishida, T., Christenson, L. K., Fujimoto, T. & Hiroi, H. START domain proteins and the intracellular trafficking of cholesterol in steroidogenic cells. Mol. Cell Endocrinol. 202, 59-65 (2003).
    • (2003) Mol. Cell Endocrinol. , vol.202 , pp. 59-65
    • Strauss, J.F.1    Kishida, T.2    Christenson, L.K.3    Fujimoto, T.4    Hiroi, H.5
  • 24
    • 17444368686 scopus 로고    scopus 로고
    • Direct observation of rapid internalization and intracellular transport of sterol by macrophage foam cells
    • Wustner, D., Mondal, M., Tabas, I. & Maxfield, F. R. Direct observation of rapid internalization and intracellular transport of sterol by macrophage foam cells. Traffic 6, 396-412 (2005).
    • (2005) Traffic , vol.6 , pp. 396-412
    • Wustner, D.1    Mondal, M.2    Tabas, I.3    Maxfield, F.R.4
  • 25
    • 11144355005 scopus 로고    scopus 로고
    • Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport
    • Sleat, D. E. et al. Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport. Proc. Natl Acad. Sci. USA 101, 5886-5891 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 5886-5891
    • Sleat, D.E.1
  • 26
    • 0030863352 scopus 로고    scopus 로고
    • Niemann-Pick C1 disease gene: Homology to mediators of cholesterol homeostasis
    • Carstea, E. et al. Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science 277, 228-231 (1997).
    • (1997) Science , vol.277 , pp. 228-231
    • Carstea, E.1
  • 27
    • 0034717894 scopus 로고    scopus 로고
    • Intracellular cholesterol trafficking: Role of the NPC1 protein
    • Blanchette-Mackie, E. Intracellular cholesterol trafficking: role of the NPC1 protein. Biochim Biophys Acta 1486, 171-183 (2000).
    • (2000) Biochim. Biophys. Acta , vol.1486 , pp. 171-183
    • Blanchette-Mackie, E.1
  • 28
    • 4744376060 scopus 로고    scopus 로고
    • Lipid and cholesterol trafficking in NPC
    • Mukherjee, S. & Maxfield, F. R. Lipid and cholesterol trafficking in NPC. Biochim. Biophys. Acta 1685, 28-37 (2004).
    • (2004) Biochim. Biophys. Acta , vol.1685 , pp. 28-37
    • Mukherjee, S.1    Maxfield, F.R.2
  • 29
    • 0030943621 scopus 로고    scopus 로고
    • Acyl-coenzyme A:cholesterol acyltransferase
    • Chang, T. Y., Chang, C. C. & Cheng, D. Acyl-coenzyme A:cholesterol acyltransferase. Annu. Rev. Biochem. 66, 613-638 (1997).
    • (1997) Annu. Rev. Biochem. , vol.66 , pp. 613-638
    • Chang, T.Y.1    Chang, C.C.2    Cheng, D.3
  • 30
    • 1842855257 scopus 로고    scopus 로고
    • Hormone-sensitive lipase - New roles for an old enzyme
    • Yeaman, S. J. Hormone-sensitive lipase - new roles for an old enzyme. Biochem. J. 379, 11-22 (2004).
    • (2004) Biochem. J. , vol.379 , pp. 11-22
    • Yeaman, S.J.1
  • 31
    • 0036790413 scopus 로고    scopus 로고
    • Consequences of cellular cholesterol accumulation: Basic concepts and physiological implications
    • Tabas, I. Consequences of cellular cholesterol accumulation: basic concepts and physiological implications J. Clin. Invest. 110, 905-911 (2002).
    • (2002) J. Clin. Invest. , vol.110 , pp. 905-911
    • Tabas, I.1
  • 32
    • 0038175518 scopus 로고    scopus 로고
    • Cholesterol is superior to 7-ketocholesterol or 7 alpha- hydroxycholesterol as an allosteric activator for acyl-coenzyme A:cholesterol acyltransferase 1
    • Zhang, Y. et al. Cholesterol is superior to 7-ketocholesterol or 7 alpha-hydroxycholesterol as an allosteric activator for acyl-coenzyme A:cholesterol acyltransferase 1. J. Biol. Chem. 278, 11642-11647 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 11642-11647
    • Zhang, Y.1
  • 33
    • 4143069270 scopus 로고    scopus 로고
    • How cholesterol homeostasis is regulated by plasma membrane cholesterol in excess of phospholipids
    • Lange, Y., Ye, J. & Steck, T. L. How cholesterol homeostasis is regulated by plasma membrane cholesterol in excess of phospholipids. Proc. Natl Acad. Sci. USA 101, 11664-11667 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 11664-11667
    • Lange, Y.1    Ye, J.2    Steck, T.L.3
  • 34
    • 0033613147 scopus 로고    scopus 로고
    • A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
    • Brown, M. S. & Goldstein, J. L. A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc. Natl Acad. Sci. USA 96, 11041-11048 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11041-11048
    • Brown, M.S.1    Goldstein, J.L.2
  • 35
    • 0036790522 scopus 로고    scopus 로고
    • Regulation and mechanisms of macrophage cholesterol efflux
    • Tall, A. R., Costet, P. & Wang, N. Regulation and mechanisms of macrophage cholesterol efflux. J. Clin. Invest. 110, 899-904 (2002).
    • (2002) J. Clin. Invest. , vol.110 , pp. 899-904
    • Tall, A.R.1    Costet, P.2    Wang, N.3
  • 36
    • 14644404294 scopus 로고    scopus 로고
    • Function of prokaryotic and eukaryotic ABC proteins in lipid transport
    • Pohl, A., Devaux, P. F.& Herrmann, A. Function of prokaryotic and eukaryotic ABC proteins in lipid transport. Biochim. Biophys. Acta 1733, 29-52 (2005).
    • (2005) Biochim. Biophys. Acta , vol.1733 , pp. 29-52
    • Pohl, A.1    Devaux, P.F.2    Herrmann, A.3
  • 38
    • 0037458568 scopus 로고    scopus 로고
    • Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure
    • Sun, Y. et al. Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure. J. Biol. Chem. 278, 5813-5820 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 5813-5820
    • Sun, Y.1
  • 39
    • 0038448097 scopus 로고    scopus 로고
    • Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux
    • Wang, N. & Tall, A. R. Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux. Arterioscler. Thromb. Vasc. Biol. 23, 1178-1184 (2003).
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 1178-1184
    • Wang, N.1    Tall, A.R.2
  • 40
    • 0342316532 scopus 로고    scopus 로고
    • Oxysterols: Modulators of cholesterol metabolism and other processes
    • Schroepfer, G. Oxysterols: modulators of cholesterol metabolism and other processes. Physiol. Rev. 80, 361-554 (2000).
    • (2000) Physiol. Rev. , vol.80 , pp. 361-554
    • Schroepfer, G.1
  • 41
    • 0142123179 scopus 로고    scopus 로고
    • Retinoic acid receptor-mediated induction of ABCA1 in macrophages
    • Costet, P. et al. Retinoic acid receptor-mediated induction of ABCA1 in macrophages. Mol. Cell Biol. 23, 7756-7766 (2003).
    • (2003) Mol. Cell Biol. , vol.23 , pp. 7756-7766
    • Costet, P.1
  • 42
    • 0035976638 scopus 로고    scopus 로고
    • Nuclear receptors and lipid physiology: Opening the X-files
    • Chawla, A., Repa, J. J., Evans, R. M. & Mangelsdorf, D. J. Nuclear receptors and lipid physiology: opening the X-files. Science 294, 1866-1870 (2001).
    • (2001) Science , vol.294 , pp. 1866-1870
    • Chawla, A.1    Repa, J.J.2    Evans, R.M.3    Mangelsdorf, D.J.4
  • 43
    • 0036321948 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A1 and cholesterol trafficking
    • Oram, J. F. ATP-binding cassette transporter A1 and cholesterol trafficking. Curr. Opin. Lipidol. 13, 373-381 (2002).
    • (2002) Curr. Opin. Lipidol. , vol.13 , pp. 373-381
    • Oram, J.F.1
  • 44
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton, J. D., Goldstein, J. L. & Brown, M. S. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109, 1125-1131 (2002).
    • (2002) J. Clin. Invest. , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 45
    • 23944435868 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid regulation of genes of lipid metabolism
    • Sampath, H. & Ntambi, J. M. Polyunsaturated fatty acid regulation of genes of lipid metabolism. Annu. Rev. Nutr. 25, 317-340 (2005).
    • (2005) Annu. Rev. Nutr. , vol.25 , pp. 317-340
    • Sampath, H.1    Ntambi, J.M.2
  • 46
    • 25444443570 scopus 로고    scopus 로고
    • Principles of lysosomal membrane digestion-stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids
    • Kolter, T. & Sandhoff, K. Principles of lysosomal membrane digestion-stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids. Annu. Rev. Cell Dev. Biol. 21, 81-103 (2004).
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.21 , pp. 81-103
    • Kolter, T.1    Sandhoff, K.2
  • 47
    • 0033145510 scopus 로고    scopus 로고
    • Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport
    • Kobayashi, T. et al. Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport. Nature Cell Biol. 1, 113-118 (1999).
    • (1999) Nature Cell Biol. , vol.1 , pp. 113-118
    • Kobayashi, T.1
  • 49
    • 0037418188 scopus 로고    scopus 로고
    • Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease
    • Friedland, N., Liou, H. L., Lobel, P. & Stock, A. M. Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease. Proc. Natl Acad. Sci. USA 100, 2512-2517 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2512-2517
    • Friedland, N.1    Liou, H.L.2    Lobel, P.3    Stock, A.M.4
  • 50
    • 0037762569 scopus 로고    scopus 로고
    • Endocytic trafficking of glycosphingolipids in sphingolipid storage diseases
    • Pagano, R. E. Endocytic trafficking of glycosphingolipids in sphingolipid storage diseases. Phil. Trans. R. Soc. Lond. B 358, 885-891 (2003).
    • (2003) Phil. Trans. R. Soc. Lond. B , vol.358 , pp. 885-891
    • Pagano, R.E.1
  • 51
    • 2942750350 scopus 로고    scopus 로고
    • ATP-binding cassette (ABC) transporters in human metabolism and diseases
    • Stefkova, J., Poledne, R. & Hubacek, J. A. ATP-binding cassette (ABC) transporters in human metabolism and diseases. Physiol. Res. 53, 235-243 (2004).
    • (2004) Physiol. Res. , vol.53 , pp. 235-243
    • Stefkova, J.1    Poledne, R.2    Hubacek, J.A.3
  • 52
    • 0029299438 scopus 로고
    • The response-to-retention hypothesis of early atherogenesis
    • Williams, K. J. & Tabas, I. The response-to-retention hypothesis of early atherogenesis. Arterioscler. Thromb. Vasc. Biol. 15, 551-561 (1995).
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 551-561
    • Williams, K.J.1    Tabas, I.2
  • 53
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson, G. K. Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 352, 1685-1695 (2005).
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 55
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis. The road ahead
    • Glass, C. K. & Witztum, J. L. Atherosclerosis. The road ahead. Cell 104, 503-516 (2001).
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 56
    • 0020972414 scopus 로고
    • Lipoprotein metabolism in the macrophage: Implications for cholesterol deposition in atherosclerosis
    • Brown, M. S. & Goldstein, J. L. Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annu. Rev. Biochem. 52, 223-261 (1983).
    • (1983) Annu. Rev. Biochem. , vol.52 , pp. 223-261
    • Brown, M.S.1    Goldstein, J.L.2
  • 57
    • 12544258729 scopus 로고    scopus 로고
    • Macropinocytosis is the endocytic pathway that mediates macrophage foam cell formation with native low density lipoprotein
    • Kruth, H. S. et al. Macropinocytosis is the endocytic pathway that mediates macrophage foam cell formation with native low density lipoprotein. J. Biol. Chem. 280, 2352-2360 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 2352-2360
    • Kruth, H.S.1
  • 58
    • 0033527535 scopus 로고    scopus 로고
    • Unique cellular events occurring during the initial interaction of macrophages with matrix-retained or methylated aggregated low density lipoprotein (LDL). Prolonged cell-surface contact during which LDL-cholesteryl ester hydrolysis exceeds LDL protein degradation
    • Buton, X. et al. Unique cellular events occurring during the initial interaction of macrophages with matrix-retained or methylated aggregated low density lipoprotein (LDL). Prolonged cell-surface contact during which LDL-cholesteryl ester hydrolysis exceeds LDL protein degradation. J. Biol. Chem. 274, 32112-32121 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 32112-32121
    • Buton, X.1
  • 59
    • 0035813170 scopus 로고    scopus 로고
    • The uptake and degradation of matrix-bound lipoproteins by macrophages require an intact actin cytoskeleton, Rho family GTPases, and myosin ATPase activity
    • Sakr, S. W. et al. The uptake and degradation of matrix-bound lipoproteins by macrophages require an intact actin cytoskeleton, Rho family GTPases, and myosin ATPase activity. J. Biol. Chem. 276, 37649-37658 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 37649-37658
    • Sakr, S.W.1
  • 61
    • 0019491124 scopus 로고
    • The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions
    • Gerrity, R. G. The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions. Am J. Pathol. 103, 181-190 (1981).
    • (1981) Am J. Pathol. , vol.103 , pp. 181-190
    • Gerrity, R.G.1
  • 62
    • 0032810502 scopus 로고    scopus 로고
    • Nonoxidative modifications of lipoproteins in atherogenesis
    • Tabas, I. Nonoxidative modifications of lipoproteins in atherogenesis. Annu. Rev. Nutr. 19, 123-139 (1999).
    • (1999) Annu. Rev. Nutr. , vol.19 , pp. 123-139
    • Tabas, I.1
  • 63
    • 0030895048 scopus 로고    scopus 로고
    • A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection
    • Suzuki, H. et al. A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature 386, 292-296 (1997).
    • (1997) Nature , vol.386 , pp. 292-296
    • Suzuki, H.1
  • 64
    • 0034833822 scopus 로고    scopus 로고
    • CD36: A class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism
    • Febbraio, M., Hajjar, D. P. & Silverstein, R. L. CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism. J. Clin. Invest. 108, 785-791 (2001).
    • (2001) J. Clin. Invest. , vol.108 , pp. 785-791
    • Febbraio, M.1    Hajjar, D.P.2    Silverstein, R.L.3
  • 65
    • 23644435612 scopus 로고    scopus 로고
    • Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice
    • Moore, K. J. et al. Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice. J. Clin. Invest. 115, 2192-2201 (2005).
    • (2005) J. Clin. Invest. , vol.115 , pp. 2192-2201
    • Moore, K.J.1
  • 66
    • 14244251463 scopus 로고    scopus 로고
    • Oxidation, lipoproteins, and atherosclerosis: Which is wrong, the antioxidants or the theory?
    • Williams, K. J. & Fisher, E. A. Oxidation, lipoproteins, and atherosclerosis: which is wrong, the antioxidants or the theory? Curr. Opin. Clin. Nutr. Metab. Care 8, 139-146 (2005).
    • (2005) Curr. Opin. Clin. Nutr. Metab. Care , vol.8 , pp. 139-146
    • Williams, K.J.1    Fisher, E.A.2
  • 68
    • 23244462754 scopus 로고    scopus 로고
    • A role for the apoptosis inhibitory factor AIM/Spa/Api6 in atherosclerosis development
    • Arai, S. et al. A role for the apoptosis inhibitory factor AIM/Spa/Api6 in atherosclerosis development. Cell Metabolism 1, 201-213 (2005).
    • (2005) Cell Metabolism , vol.1 , pp. 201-213
    • Arai, S.1
  • 69
    • 0027376554 scopus 로고
    • The role of macrophages in atherosclerosis
    • Libby, P. & Clinton, S. K. The role of macrophages in atherosclerosis. Curr. Opin. Lipidol. 4, 355-363 (1993).
    • (1993) Curr. Opin. Lipidol. , vol.4 , pp. 355-363
    • Libby, P.1    Clinton, S.K.2
  • 70
    • 20444481448 scopus 로고    scopus 로고
    • Clinical practice. Chronic stable angina
    • Abrams, J. Clinical practice. Chronic stable angina. N. Engl. J. Med 352, 2524-2533 (2005).
    • (2005) N. Engl. J. Med , vol.352 , pp. 2524-2533
    • Abrams, J.1
  • 71
    • 1842662594 scopus 로고    scopus 로고
    • The vulnerable atherosclerotic plaque: Pathogenesis and therapeutic approach
    • Aikawa, M. & Libby, P. The vulnerable atherosclerotic plaque: pathogenesis and therapeutic approach. Cardiovasc. Pathol. 13, 125-138 (2004).
    • (2004) Cardiovasc. Pathol. , vol.13 , pp. 125-138
    • Aikawa, M.1    Libby, P.2
  • 72
    • 17644398144 scopus 로고    scopus 로고
    • Insights into the molecular mechanisms of plaque rupture and thrombosis
    • Shah, P. K. Insights into the molecular mechanisms of plaque rupture and thrombosis. Indian Heart J. 57, 21-30 (2005).
    • (2005) Indian Heart J. , vol.57 , pp. 21-30
    • Shah, P.K.1
  • 73
    • 4043110643 scopus 로고    scopus 로고
    • Evolving concepts in the triad of atherosclerosis, inflammation and thrombosis
    • Corti, R., Hutter, R., Badimon, J. J. & Fuster, V. Evolving concepts in the triad of atherosclerosis, inflammation and thrombosis. J. Thromb. Thrombolysis 17, 35-44 (2004).
    • (2004) J. Thromb. Thrombolysis , vol.17 , pp. 35-44
    • Corti, R.1    Hutter, R.2    Badimon, J.J.3    Fuster, V.4
  • 74
    • 0036892838 scopus 로고    scopus 로고
    • Vulnerable plaque: The pathology of unstable coronary lesions
    • Virmani, R., Burke, A. P., Kolodgie, F. D. & Farb, A. Vulnerable plaque: the pathology of unstable coronary lesions. J. Interv. Cardiol. 15, 439-446 (2002).
    • (2002) J. Interv. Cardiol. , vol.15 , pp. 439-446
    • Virmani, R.1    Burke, A.P.2    Kolodgie, F.D.3    Farb, A.4
  • 75
    • 0029807088 scopus 로고    scopus 로고
    • Macrophages and atherosclerotic plaque stability
    • Libby, P. et al. Macrophages and atherosclerotic plaque stability. Curr. Opin. Lipidol. 7, 330-335 (1996).
    • (1996) Curr. Opin. Lipidol. , vol.7 , pp. 330-335
    • Libby, P.1
  • 76
    • 0036739920 scopus 로고    scopus 로고
    • Progression of atheroma: A struggle between death and procreation
    • Geng, Y. J. & Libby, P. Progression of atheroma: a struggle between death and procreation. Arterioscler. Thromb. Vasc. Biol. 22, 1370-1380 (2002).
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 1370-1380
    • Geng, Y.J.1    Libby, P.2
  • 77
    • 4344652838 scopus 로고    scopus 로고
    • Apoptosis and plaque destabilization in atherosclerosis: the role of macrophage apoptosis induced by cholesterol
    • Tabas, I. Apoptosis and plaque destabilization in atherosclerosis: the role of macrophage apoptosis induced by cholesterol. Cell Death Differ. 11 (Suppl. 1), S12-S16 (2004).
    • (2004) Cell Death Differ. , vol.11 , Issue.1 SUPPL.
    • Tabas, I.1
  • 79
    • 27644537437 scopus 로고    scopus 로고
    • Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis. The importance of lesion stage and phagocytic efficiency
    • Tabas, I. Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis. The importance of lesion stage and phagocytic efficiency. Arterioscler. Thromb. Vasc. Biol. 25, 2255-2264 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 2255-2264
    • Tabas, I.1
  • 80
    • 0031662304 scopus 로고    scopus 로고
    • Apoptosis in the atherosclerotic plaque: Quantitative and qualitative aspects
    • Kockx, M. M. Apoptosis in the atherosclerotic plaque: quantitative and qualitative aspects. Arterioscler. Thromb. Vasc. Biol. 18, 1519-1522 (1998).
    • (1998) Arterioscler. Thromb. Vasc. Biol. , vol.18 , pp. 1519-1522
    • Kockx, M.M.1
  • 82
    • 4344578601 scopus 로고    scopus 로고
    • Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: Implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages
    • Li, Y. et al. Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages. J. Biol. Chem. 279, 37030-37039 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 37030-37039
    • Li, Y.1
  • 83
    • 0042972934 scopus 로고    scopus 로고
    • The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages
    • Feng, B. et al. The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages. Nature Cell Biol. 5, 781-792 (2003).
    • (2003) Nature Cell Biol. , vol.5 , pp. 781-792
    • Feng, B.1
  • 84
    • 0036853914 scopus 로고    scopus 로고
    • Orchestrating the unfolded protein response in health and disease
    • Kaufman, R. J. Orchestrating the unfolded protein response in health and disease. J. Clin. Invest. 110, 1389-1398 (2002).
    • (2002) J. Clin. Invest. , vol.110 , pp. 1389-1398
    • Kaufman, R.J.1
  • 85
    • 0041335569 scopus 로고    scopus 로고
    • Niemann-Pick C heterozygosity confers resistance to lesional necrosis and macrophage apoptosis in murine atherosclerosis
    • Feng, B. et al. Niemann-Pick C heterozygosity confers resistance to lesional necrosis and macrophage apoptosis in murine atherosclerosis. Proc. Natl Acad. Sci. USA 100, 10423-10428 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 10423-10428
    • Feng, B.1
  • 86
    • 17144419252 scopus 로고    scopus 로고
    • Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice
    • Zhou, J., Lhotak, S., Hilditch, B. A. & Austin, R. C. Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice. Circulation 111, 1814-1821 (2005).
    • (2005) Circulation , vol.111 , pp. 1814-1821
    • Zhou, J.1    Lhotak, S.2    Hilditch, B.A.3    Austin, R.C.4
  • 87
    • 20444461628 scopus 로고    scopus 로고
    • Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-α and interleukin-6: Model of NK-κB- And Map kinase-dependent inflammation in advanced atherosclerosis
    • Li, Y. et al. Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-α and interleukin-6: Model of NK-κB- and Map kinase-dependent inflammation in advanced atherosclerosis. J. Biol. Chem. 280, 21763-21772 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 21763-21772
    • Li, Y.1
  • 88
    • 0021137028 scopus 로고
    • Fluorescence probes in metastatic B16 melanoma membranes
    • Schroeder, F. Fluorescence probes in metastatic B16 melanoma membranes. Biochim. Biophys. Acta 776, 299-312 (1984).
    • (1984) Biochim. Biophys. Acta , vol.776 , pp. 299-312
    • Schroeder, F.1
  • 89
    • 3042736080 scopus 로고    scopus 로고
    • Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention
    • Mo, H. & Elson, C. E. Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention. Exp. Biol. Med. 229, 567-585 (2004).
    • (2004) Exp. Biol. Med. , vol.229 , pp. 567-585
    • Mo, H.1    Elson, C.E.2
  • 90
  • 91
    • 10344263931 scopus 로고    scopus 로고
    • Neuronal membrane cholesterol loss enhances amyloid peptide generation
    • Abad-Rodriguez, J. et al. Neuronal membrane cholesterol loss enhances amyloid peptide generation. J. Cell Biol. 167, 953-960 (2004).
    • (2004) J. Cell Biol. , vol.167 , pp. 953-960
    • Abad-Rodriguez, J.1
  • 92
    • 0034707082 scopus 로고    scopus 로고
    • Insolubility of lipids in Triton X-100: Physical origin and relationship to sphingolipid/cholesterol membrane domains (rafts)
    • London, E. & Brown, D. A. Insolubility of lipids in Triton X-100: physical origin and relationship to sphingolipid/cholesterol membrane domains (rafts). Biochim. Biophys. Acta 1508, 182-195 (2000).
    • (2000) Biochim. Biophys. Acta , vol.1508 , pp. 182-195
    • London, E.1    Brown, D.A.2
  • 93
    • 0033065591 scopus 로고    scopus 로고
    • A microscopic interaction model of maximum solubility of cholesterol in lipid bilayers
    • Huang, J. & Feigenson, G. W. A microscopic interaction model of maximum solubility of cholesterol in lipid bilayers. Biophys. J. 76, 2142-2157 (1999).
    • (1999) Biophys. J. , vol.76 , pp. 2142-2157
    • Huang, J.1    Feigenson, G.W.2
  • 94
    • 0037429704 scopus 로고    scopus 로고
    • Condensed complexes of cholesterol and phospholipids
    • McConnell, H. M. & Radhakrishnan, A. Condensed complexes of cholesterol and phospholipids. Biochim. Biophys. Acta 1610, 159-173 (2003).
    • (2003) Biochim. Biophys. Acta , vol.1610 , pp. 159-173
    • McConnell, H.M.1    Radhakrishnan, A.2
  • 95
    • 0032527642 scopus 로고    scopus 로고
    • Structure and origin of ordered lipid domains in biological membranes
    • Brown, D. A. & London, E. Structure and origin of ordered lipid domains in biological membranes. J. Membr. Biol. 164, 103-114 (1998).
    • (1998) J. Membr. Biol. , vol.164 , pp. 103-114
    • Brown, D.A.1    London, E.2
  • 96
    • 0035016931 scopus 로고    scopus 로고
    • Ternary phase diagram of dipalmitoyl-PC/dilauroyl-PC/cholesterol: Nanoscopic domain formation driven by cholesterol
    • Feigenson, G. W. & Buboltz, J. T. Ternary phase diagram of dipalmitoyl-PC/dilauroyl-PC/cholesterol: nanoscopic domain formation driven by cholesterol. Biophys. J. 80, 2775-2788 (2001).
    • (2001) Biophys. J. , vol.80 , pp. 2775-2788
    • Feigenson, G.W.1    Buboltz, J.T.2
  • 97
    • 1642293929 scopus 로고    scopus 로고
    • Ceramide selectively displaces cholesterol from ordered lipid domains (rafts): Implications for lipid raft structure and function
    • Megha & London, E. Ceramide selectively displaces cholesterol from ordered lipid domains (rafts): implications for lipid raft structure and function. J. Biol. Chem. 279, 9997-10004 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 9997-10004
    • Megha1    London, E.2
  • 98
    • 0037216849 scopus 로고    scopus 로고
    • Sphingolipid partitioning into ordered domains in cholesterol-free and cholesterol-containing lipid bilayers
    • Wang, T. Y. & Silvius, J. R. Sphingolipid partitioning into ordered domains in cholesterol-free and cholesterol-containing lipid bilayers. Biophys. J. 84, 367-378 (2003).
    • (2003) Biophys. J. , vol.84 , pp. 367-378
    • Wang, T.Y.1    Silvius, J.R.2
  • 99
    • 8544251324 scopus 로고    scopus 로고
    • Expression and regulation of multiple murine ATP-binding cassette transporter G1 mRNAs/isoforms that stimulate cellular cholesterol efflux to high density lipoprotein
    • Nakamura, K. et al. Expression and regulation of multiple murine ATP-binding cassette transporter G1 mRNAs/isoforms that stimulate cellular cholesterol efflux to high density lipoprotein. J. Biol. Chem. 279, 45980-45989 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 45980-45989
    • Nakamura, K.1
  • 100
    • 3042798281 scopus 로고    scopus 로고
    • ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins
    • Wang, N., Lan, D., Chen, W., Matsuura, F. & Tall, A. R. ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proc. Natl Acad. Sci USA 101, 9774-9779 (2004).
    • (2004) Proc. Natl Acad. Sci USA , vol.101 , pp. 9774-9779
    • Wang, N.1    Lan, D.2    Chen, W.3    Matsuura, F.4    Tall, A.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.