Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions

Journal of Biological Chemistry

Volumn 284, Issue 3, 2009, Pages 1755-1764

  Gale, Sarah E ^a   Westover, Emily J ^b   Dudley, Nicole ^a   Krishnan, Kathiresan ^b   Merlin, Sean ^a   Scherrer, David E ^a   Han, Xianlin ^a   Zhai, Xiuhong ^c   Brockman, Howard L ^c   Brown, Rhoderick E ^c   Covey, Douglas F ^b   Schaffer, Jean E ^a,b   Schlesinger, Paul ^a   Ory, Daniel S ^a,b  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CHAINS; BI LAYERS; CELLULAR CHOLESTEROLS; CULTURED CELLS; ENANTIOSPECIFIC; EXPANSION BEHAVIORS; HYDROXYMETHYLGLUTARYL; IN-VITRO; MEMBRANE PHOSPHOLIPIDS; OXYSTEROL; OXYSTEROLS; PHOSPHOLIPID MONOLAYERS; PROTEIN INTERACTIONS; SATURATED FATTY ACIDS; SIDE CHAINS; STEROL REGULATORY ELEMENT-BINDING PROTEINS;

ALCOHOLS; BODY FLUIDS; CHOLESTEROL; FATTY ACIDS; LAWS AND LEGISLATION; LEAD; MEMBRANES; PHOSPHOLIPIDS;

CELL MEMBRANES;

25 HYDROXYCHOLESTEROL; OXYSTEROL; PHOSPHOLIPID; SATURATED FATTY ACID;

ANIMAL CELL; ARTICLE; CELL CULTURE; CHOLESTEROL METABOLISM; CHOLESTEROL SIDE CHAIN CLEAVAGE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; ENANTIOMER; ENDOPLASMIC RETICULUM; HOMEOSTASIS; IN VITRO STUDY; LIPID MEMBRANE; LIPID MONOLAYER; MOLECULAR MECHANICS; NONHUMAN; PHOSPHOLIPID BILAYER; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION;

ANIMALS; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; ENDOPLASMIC RETICULUM; FATTY ACIDS; HOMEOSTASIS; HYDROXYCHOLESTEROLS; HYDROXYMETHYLGLUTARYL COA REDUCTASES;

EID: 59449086786     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807210200     Document Type: Article

References (35)

1. Radhakrishnan, A., Sun, L. P., Kwon, H. J., Brown, M. S., and Goldstein, J. L. (2004) Mol. Cell 15, 259-268
2. Adams, C. M., Reitz, J., De Brabander, J. K., Feramisco, J. D., Li, L., Brown, M. S., and Goldstein, J. L. (2004) J. Biol. Chem. 279, 52772-52780
3. Chawla, A., Repa, J. J., Evans, R. M., and Mangelsdorf, D. J. (2001) Science 294, 1866-1870
4. Brown, A. J., Sun, L., Feramisco, J. D., Brown, M. S., and Goldstein, J. L. (2002) Mol. Cell 10, 237-245
5. Radhakrishnan, A., Ikeda, Y., Kwon, H. J., Brown, M. S., and Goldstein, J. L. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 6511- 6518
6. Song, B. L., Javitt, N. B., and DeBose-Boyd, R. A. (2005) Cell Metab. 1, 179-189
7. Lange, Y., Ory, D. S., Ye, J., Lanier, M. H., Hsu, F. F., and Steck, T. L. (2008) J. Biol. Chem. 283, 1445-1455
8. Frolov, A., Zielinski, S. E., Crowley, J. R., Dudley-Rucker, N., Schaffer, J. E., and Ory, D. S. (2003) J. Biol. Chem. 278, 25517-25525
9. Lange, Y. (1994) J. Biol. Chem. 269, 3411-3414
10. Lange, Y., Ye, J., and Steck, T. L. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 11664-11667
11. Massey, J. B., and Pownall, H. J. (2006) Biochemistry 45, 10747-10758
12. Westover, E. J., and Covey, D. F. (2006) Steroids 71, 484-488
13. Hannah, V. C., Ou, J., Luong, A., Goldstein, J. L., and Brown, M. S. (2001) J. Biol. Chem. 276, 4365-4372
14. Worgall, T. S., Johnson, R. A., Seo, T., Gierens, H., and Deckelbaum, R. J. (2002) J. Biol. Chem. 277, 3878-3885
15. Worgall, T. S., Sturley, S. L., Seo, T., Osborne, T. F., and Deckelbaum, R. J. (1998) J. Biol. Chem. 273, 25537-25540
16. Cruz, J. C., Sugii, S., Yu, C., and Chang, T. Y. (2000) J. Biol. Chem. 275, 4013-4021
17. Millard, E., Gale, S., Dudley, N., Zhang, J., Schaffer, J., and Ory, D. (2005) J. Biol. Chem. 280, 28581-28590
18. Smaby, J. M., Momsen, M. M., Brockman, H. L., and Brown, R. E. (1997) Biophys. J. 73, 1492-1505
19. Szoka, F., Jr., and Papahadjopoulos, D. (1978) Proc. Natl. Acad. Sci. U. S.A. 75, 4194-4198
20. Rex, S., and Schwarz, G. (1998) Biochemistry 37, 2336-2345
21. Borradaile, N. M., Han, X., Harp, J. D., Gale, S. E., Ory, D. S., and Schaffer, J. E. (2006) J. Lipid Res. 47, 2726-2737
22. Gale, S. E., Frolov, A., Han, X., Bickel, P. E., Cao, L., Bowcock, A., Schaffer, J. E., and Ory, D. S. (2006) J. Biol. Chem. 281, 11082-11089
23. Westover, E. J., and Covey, D. F. (2004) J. Membr. Biol. 202, 61-72
24. Wang, Y., Rogers, P. M., Su, C., Varga, G., Stayrook, K. R., and Burris, T. P. (2008) J. Biol. Chem. 283, 26332-26339
25. Westover, E. J., Covey, D. F., Brockman, H. L., Brown, R. E., and Pike, L. J. (2003) J. Biol. Chem. 278, 51125-51133
26. Mathai, J. C., Tristram-Nagle, S., Nagle, J. F., and Zeidel, M. L. (2008) J. Gen. Physiol. 131, 69-76
27. Lange, Y., Ye, J., Rigney, M., and Steck, T. L. (1999) J. Lipid Res. 40, 2264-2270
28. Lange, Y., and Steck, T. L. (1997) J. Biol. Chem. 272, 13103-13108
29. Liu, J., Chang, C. C., Westover, E. J., Covey, D. F., and Chang, T. Y. (2005) Biochem. J. 391, 389-397
30. Wang, J., Sun, F., Zhang, D. W., Ma, Y., Xu, F., Belani, J. D., Cohen, J. C., Hobbs, H. H., and Xie, X. S. (2006) J. Biol. Chem. 281, 27894-27904
31. Kauffman, J. M., Westerman, P. W., and Carey, M. C. (2000) J. Lipid Res. 41, 991-1003
32. Lange, Y., Ye, J., Rigney, M., and Steck, T. (2000) J. Biol. Chem. 275, 17468-17475
33. Infante, R. E., Abi-Mosleh, L., Radhakrishnan, A., Dale, J. D., Brown, M. S., and Goldstein, J. L. (2008) J. Biol. Chem. 283, 1052-1063
34. Aittoniemi, J., Rog, T., Niemela, P., Pasenkiewicz-Gierula, M., Karttunen, M., and Vattulainen, I. (2006) J. Phys. Chem. B 110, 25562-25564
35. Phillips, J. E., Geng, Y. J., and Mason, R. P. (2001) Atherosclerosis 159, 125-135